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https://www.readbyqxmd.com/read/28820778/src-kinase-inhibition-attenuates-morphine-tolerance-without-affecting-reinforcement-or-psychomotor-stimulation
#1
Fiona A Bull, Daniel T Baptista-Hon, Claire Sneddon, Lisa Wright, Wendy Walwyn, Tim G Hales
BACKGROUND: Prolonged opioid administration leads to tolerance characterized by reduced analgesic potency. Pain management is additionally compromised by the hedonic effects of opioids, the cause of their misuse. The multifunctional protein β-arrestin2 regulates the hedonic effects of morphine and participates in tolerance. These actions might reflect µ opioid receptor up-regulation through reduced endocytosis. β-Arrestin2 also recruits kinases to µ receptors. We explored the role of Src kinase in morphine analgesic tolerance, locomotor stimulation, and reinforcement in C57BL/6 mice...
August 18, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28820459/spices-in-a-product-affect-emotions-a-study-with-an-extruded-snack-product-%C3%A2
#2
Brandon Bell, Koushik Adhikari, Edgar Chambers, Sajid Alavi, Silvia King, Mark Haub
Food commonly is associated with emotion. The study was designed to determine if a spice blend (cinnamon, ginger, nutmeg, and cloves) high in antioxidants can evoke changes in consumer emotions. This was an exploratory study to determine the effects of these four spices on emotions. Three extruded, dry snack products containing 0, 4, or a 5% spice blend were tested. One day of hedonic and just-about-right evaluations (n = 100), followed by three days of emotion testing were conducted. A human clinical trial (n = 10), using the control and the 4% samples, measured total antioxidant capacity and blood glucose levels...
August 18, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28818429/exposure-shapes-the-perception-of-affective-touch
#3
Uta Sailer, Rochelle Ackerley
Touch is a common occurrence in our lives, where affective and inter-personal aspects of touch are important for our well-being. We investigated whether touch exposure affects hedonic and discriminative aspects of tactile perception. The perceived pleasantness and intensity of gentle forearm stroking, over different velocities, was assessed in individuals reporting to seldom receive inter-personal touch, and in controls who received touch often. The groups did not differ in their stroking intensity judgements, nor in tactile discrimination sensitivity; however, individuals with low touch exposure evaluated the pleasantness of touch differently...
August 9, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28814527/effects-of-nicotine-on-homeostatic-and-hedonic-components-of-food-intake
#4
REVIEW
Andrea Stojakovic, Enma P Espinosa, Osman T Farhad, Kabirullah Lutfy
Chronic tobacco use leads to nicotine addiction that is characterized by exaggerated urges to use the drug despite the accompanying negative health and socioeconomic burdens. Interestingly, nicotine users are found to be leaner than the general population. Review of the existing literature revealed that nicotine affects energy homeostasis and food consumption via altering the activity of neurons containing orexigenic and anorexigenic peptides in the brain. Hypothalamus is one of the critical brain areas that regulates energy balance via the action of these neuropeptides...
October 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28806614/altered-interaction-with-environmental-reinforcers-in-major-depressive-disorder-relationship-to-anhedonia
#5
Joanna E Szczepanik, Maura L Furey, Allison C Nugent, Ioline D Henter, Carlos A Zarate, Carl W Lejuez
Anhedonia-defined as loss of interest or pleasure-is one of two core symptoms of major depressive disorder (MDD). Anhedonia may involve decreased enjoyment of potentially rewarding activities and decreased motivation to engage in such activities. Increased engagement with reinforcers-activities with the potential to be positive experiences-is a frequent target of cognitive-behavioral therapies. Nevertheless, how environmental reinforcers are perceived, and how decisions to approach or avoid them are made by individuals with MDD, is largely unknown...
August 3, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28804473/confirmatory-factor-analysis-of-the-french-version-of-the-anticipatory-and-consummatory-interpersonal-pleasure-scale
#6
Joséphine Chaix, Philippe Golay, Caroline Fankhauser, Alexandra Nguyen, Diane C Gooding, Jérôme Favrod
The Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS), a measure specifically designed to assess hedonic capacity for social and interpersonal pleasure, was used to evaluate the presence of social anhedonia in patients as well as the general population. The first goal of this study was to validate the structure of the French version of the ACIPS. The second objective was to verify whether a one, two or three factor solution is most appropriate for the ACIPS scale. The French version of the ACIPS was tested on 263 French-speaking pre-graduate students or professional volunteers...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28803023/consumer-acceptance-of-dairy-products-with-a-saturated-fatty-acid-reduced-monounsaturated-fatty-acid-enriched-content
#7
Oonagh Markey, Kallis Souroullas, Colette C Fagan, Kirsty E Kliem, Dafni Vasilopoulou, Kim G Jackson, David J Humphries, Alistair S Grandison, David I Givens, Julie A Lovegrove, Lisa Methven
Agriculture-based reformulation initiatives, including oleic acid-rich lipid supplementation of the dairy cow diet, provide a novel means for reducing intake of saturated fatty acids (SFA) at a population level. In a blinded manner, this study evaluated the consumer acceptance of SFA-reduced, monounsaturated fatty acid-enriched (modified) milk, Cheddar cheese, and butter when compared with control and commercially available comparative samples. The effect of providing nutritional information about the modified cheese was also evaluated...
August 9, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28797701/cross-sectional-and-longitudinal-associations-between-different-exercise-types-and-food-cravings-in-free-living-healthy-young-adults
#8
Clemens Drenowatz, Line H Evensen, Linda Ernstsen, John E Blundell, Gregory A Hand, Robin P Shook, James R Hébert, Stephanie Burgess, Steven N Blair
INTRODUCTION: An increase in energy intake due to alterations in hedonic appetite sensations may, at least in part, contribute to lower-than-expected weight loss in exercise interventions. The aim of this study was to examine cross-sectional and longitudinal associations between habitual exercise participation and food cravings in free-living young adults. METHODS: A total of 417 adults (49% male, 28 ± 4 years) reported frequency and duration of walking, aerobic exercise, resistance exercise and other exercise at baseline and every 3 months over a 12-month period...
August 7, 2017: Appetite
https://www.readbyqxmd.com/read/28782446/hedonic-eating-how-the-pleasure-of-food-affects-our-brains-and-behaviour
#9
Jana Rozehnalova
No abstract text is available yet for this article.
August 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28768906/integration-of-homeostatic-signaling-and-food-reward-processing-in-the-human-brain
#10
Joe J Simon, Anne Wetzel, Maria Hamze Sinno, Mandy Skunde, Martin Bendszus, Hubert Preissl, Paul Enck, Wolfgang Herzog, Hans-Christoph Friederich
BACKGROUND: Food intake is guided by homeostatic needs and by the reward value of food, yet the exact relation between the two remains unclear. The aim of this study was to investigate the influence of different metabolic states and hormonal satiety signaling on responses in neural reward networks. METHODS: Twenty-three healthy participants underwent functional magnetic resonance imaging while performing a task distinguishing between the anticipation and the receipt of either food- or monetary-related reward...
August 3, 2017: JCI Insight
https://www.readbyqxmd.com/read/28768658/detection-of-maltodextrin-and-its-discrimination-from-sucrose-are-independent-of-the-t1r2-t1r3-heterodimer
#11
Kimberly R Smith, Alan Craig Spector
Maltodextrins, such as Maltrin and Polycose, are glucose polymer mixtures of varying chain lengths that are palatable to rodents. Although glucose and other sugars activate the T1R2+T1R3 "sweet" taste receptor, recent evidence from T1R2 or T1R3 knockout (KO) mice suggests that maltodextrins, despite their glucose polymer composition, activate a separate receptor mechanism to generate a taste percept qualitatively distinguishable from that of sweeteners. However, explicit discrimination of maltodextrins from prototypical sweeteners has not yet been psychophysically tested in any murine model...
August 2, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28760349/the-effect-of-sequential-information-on-consumers-willingness-to-pay-for-credence-food-attributes
#12
A Botelho, I Dinis, L Lourenço-Gomes, J Moreira, L Costa Pinto, O Simões
The use of experimental methods to determine consumers' willingness to pay for "quality" food has been gaining importance in scientific research. In most of the empirical literature on this issue the experimental design starts with blind tasting, after which information is introduced. It is assumed that this approach allows consumers to elicit the real value that they attach to each of the features added through specific information. In this paper, the starting hypothesis is that this technique overestimates the weight of the features introduced by information in consumers' willingness to pay when compared to a real market situation, in which consumers are confronted with all the information at once...
July 29, 2017: Appetite
https://www.readbyqxmd.com/read/28756851/guidelines-for-coordinated-radiologist-gynecologist-obstetrician-management-of-patients-requiring-fetal-mri-or-ct
#13
EDITORIAL
J-F Meder, H Ducou le Pointe, B Hédon, A Benachi
No abstract text is available yet for this article.
July 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28750893/early-pediatric-formulation-development-with-new-chemical-entities-opportunities-of-e-tongue-besides-human-taste-assessment
#14
Laura Isabell Immohr, Angela Dischinger, Peter Kühl, Heidemarie Kletzl, Stefan Sturm, Andreas Günther, Miriam Pein-Hackelbusch
The palatability of a pediatric drug formulation is one of the key prerequisites for therapeutic success. Liquid formulations are often chosen for pediatric drug products, and they require special attention regarding their taste, as they have direct contact to the taste buds and a relatively long residence time in the oral cavity. For ethical reasons, the role of electronic tongues in the development of oral drug formulations with new chemical entities (NCEs) for pediatric use is growing, however, little is known about the strategies how this instrumental taste assessment can be performed...
July 24, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28749161/self-employment-personal-values-and-varieties-of-happiness-unhappiness
#15
Peter Warr
This study compares personal values and forms of happiness between self-employed workers and those employed in an organization. Values are examined through Schwartz's (1999) established model, and happiness is measured in terms of personal flourishing and both job-specific and general hedonic well-being. In two nationally representative samples, self-employed workers are found to value self-direction and stimulation in their lives to a significantly greater degree than do organizational employees, but not to differ in other types of value...
July 27, 2017: Journal of Occupational Health Psychology
https://www.readbyqxmd.com/read/28748073/consumer-orientated-development-of-hybrid-beef-burger-and-sausage-analogues
#16
Michelle Neville, Amparo Tarrega, Louise Hewson, Tim Foster
Hybrid meat analogues, whereby a proportion of meat has been partially replaced by more sustainable protein sources, have been proposed to provide a means for more sustainable diets in the future. Consumer testing was conducted to determine consumer acceptability of different formulations of Hybrid beef burgers and pork sausages in comparison with both meat and meat-free commercial products. Acceptability data were generated using the 9-point hedonic scale. Check-all-that-apply (CATA) questioning was used to determine the sensory attributes perceived in each product as well as information on the attributes of consumers' ideal products...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28747384/feeding-releases-endogenous-opioids-in-humans
#17
Jetro J Tuulari, Lauri Tuominen, Femke de Boer, Jussi Hirvonen, Semi Helin, Pirjo Nuutila, Lauri Nummenmaa
The endogenous opioid system supports a multitude of functions related to appetitive behaviour and feeding in humans and animals, and it has been proposed to support hedonic aspects of feeding thus contributing to development of obesity. Here we used positron emission tomography (PET) to investigate whether feeding results in hedonia-dependent endogenous opioid release in humans. Ten healthy males were recruited for the study. They were scanned with mu-opioid specific ligand [(11)C]carfentanil three times: following a palatable meal, a non-palatable meal, and after an overnight fast...
July 26, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28740473/bonding-pictures-affective-ratings-are-specifically-associated-to-loneliness-but-not-to-empathy
#18
Heraldo D Silva, Rafaela R Campagnoli, Bruna Eugênia F Mota, Cássia Regina V Araújo, Roberta Sônia R Álvares, Izabela Mocaiber, Vanessa Rocha-Rego, Eliane Volchan, Gabriela G L Souza
Responding to pro-social cues plays an important adaptive role in humans. Our aims were (i) to create a catalog of bonding and matched-control pictures to compare the emotional reports of valence and arousal with the International Affective Picture System (IAPS) pictures; (ii) to verify sex influence on the valence and arousal of bonding and matched-control pictures; (iii) to investigate if empathy and loneliness traits exert a specific influence on emotional reports for the bonding pictures. To provide a finer tool for social interaction studies, the present work defined two new sets of pictures consisting of "interacting dyads" (Bonding: N = 70) and matched controls "non-interacting dyads" (Controls: N = 70)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28737712/an-investigation-of-sensory-specific-satiety-and-food-size-when-children-consume-a-whole-or-diced-vegetable
#19
Jasmine R Goh, Catherine G Russell, Djin G Liem
Children's vegetable consumption is often lower than that needed to promote optimal health and development, and practical approaches for increasing vegetable consumption are needed. Sensory Specific Satiety (SSS) reduces the liking and consumption of a consumed food over the course of an eating occasion and is an important factor in meal termination. The present study aimed to investigate the development of SSS when children ate vegetables of different sizes. The absence of SSS would be an encouraging sign to provide children more vegetables during a meal...
July 24, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28737277/investigation-of-sensory-profiles-and-hedonic-drivers-of-emerging-aquaculture-fish-species
#20
Niki Alexi, Derek V Byrne, Evagelia Nanou, Kriton Grigorakis
BACKGROUND: The aquaculture sector needs to increase the diversity in fish species and their processed products to cover rising consumer demands. Candidates for this diversification have been identified to be meagre, Greater amberjack, pikeperch, and wreckfish. Yet, scientific knowledge on their sensory profiles and consumer hedonic responses is scarce. The aim of the current study was to investigate these aspects, since they are essential for product development and market targeting...
July 24, 2017: Journal of the Science of Food and Agriculture
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