keyword
MENU ▼
Read by QxMD icon Read
search

Lymphatics

keyword
https://www.readbyqxmd.com/read/28549402/indications-for-medical-compression-stockings-in-venous-and-lymphatic-disorders-an-evidence-based-consensus-statement
#1
Eberhard Rabe, Hugo Partsch, Juerg Hafner, Christopher Lattimer, Giovanni Mosti, Martino Neumann, Tomasz Urbanek, Monika Huebner, Sylvain Gaillard, Patrick Carpentier
Objective Medical compression stockings are a standard, non-invasive treatment option for all venous and lymphatic diseases. The aim of this consensus document is to provide up-to-date recommendations and evidence grading on the indications for treatment, based on evidence accumulated during the past decade, under the auspices of the International Compression Club. Methods A systematic literature review was conducted and, using PRISMA guidelines, 51 relevant publications were selected for an evidence-based analysis of an initial 2407 unrefined results...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28549384/rapidly-growing-cystic-hygroma-in-an-adult-patient
#2
Talha Dogruyol, Halil Tozum, Tahir Sevval Eren
Cystic hygroma is a benign tumor of lymphatic tissue. It usually develops before the second year of life and is rarely seen in adults. A 26-year-old woman was referred to our clinic with a swelling in the left supraclavicular region, which had appeared 5 months earlier and grown rapidly. Ultrasonography, computed tomography, and magnetic resonance imaging showed a 7-cm cystic lesion in the neighborhood of the carotid artery and jugular vein medially and the supraclavicular region inferiorly The lesion was dissected completely from the surrounding tissue...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28549104/near-infrared-image-guided-lymphatic-mapping-in-minimally-invasive-oesophagectomy-of-distal-oesophageal-cancer
#3
Olli Helminen, Johanna Mrena, Eero Sihvo
OBJECTIVES: We aimed to assess the potential of near-infrared (NIR) imaging during minimally invasive oesophagectomy in patients with distal oesophageal cancer for detection of nodal metastases inside and outside the standard en bloc surgical field. METHODS: We enrolled 6 patients diagnosed with distal oesophageal cancer for intraoperative lymphatic mapping with NIR imaging. Indocyanine green dye was injected endoscopically in 8 corners of the primary tumour at the start of the operation...
May 26, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28549035/expression-of-ki-67-and-estrogen-receptor-beta-in-primary-cutaneous-melanoma-as-a-potential-indicator-of-regional-lymph-node-positivity
#4
Dalma Udovicic-Gagula, Amina Ahmovic, Nurija Bilalovic, Mirsad Doric
In the early stages of cutaneous malignant melanoma (MM), it is extremely difficult to predict adequately the risk from hematogenic and lymphatic metastasis. We investigate whether the immunohistochemical expression of Ki-67 and estrogen receptor beta (ERβ) in cells of MM could predict the status of regional lymph nodes. A total of 55 tissue samples of primary cutaneous melanomas with known status of regional lymph nodes were retrospectively evaluated for Ki-67 and ERβ expression by quantitative immunohistochemistry and then correlated with the status of regional lymph nodes and relevant clinicopathologic parameters...
May 25, 2017: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/28547076/purinergic-signaling-during-intestinal-inflammation
#5
REVIEW
Maria Serena Longhi, Alan Moss, Zhenghui Gordon Jiang, Simon C Robson
Inflammatory bowel disease (IBD) is a devastating disease that is associated with excessive inflammation in the intestinal tract in genetically susceptible individuals and potentially triggered by microbial dysbiosis. This illness markedly predisposes patients to thrombophilia and chronic debility as well as bowel, lymphatic, and liver cancers. Development of new therapies is needed to re-establish long-term immune tolerance in IBD patients without increasing the risk of opportunistic infections and cancer...
May 26, 2017: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/28546804/synchronous-uterine-adenocarcinoma-and-leiomyosarcoma-a-case-study
#6
Kamila Dudzik, Agnieszka Krzysteczko, Leon Kolny, Agnieszka Bąk, Ewelina Stawicka-Ociepka, Krzysztof Nowosielski
Synchronous gynecological cancers are rarely described. Those cases account for approximately up to 6% of female genital tract malignancies. The presence of synchronous endometrial adenocarcinoma and gynecological tract neoplasia is rare - the most commonly described is synchronous adenocarcinoma and endometrial ovarian cancer (accounting for 15-20% of ovarian neoplasia and 5% of endometrial cancers). Concomitant uterine carcinosarcoma and ovarian cancer, or endometrial adenocarcinoma are extremely rare. Up till now, only 3 cases of synchronous adenocarcinoma and leiomyosarcoma were described...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28546704/feasibility-of-axillary-reverse-mapping-and-clinicopathological-features-predicting-arm-node-metastasis-in-breast-cancer-a-pilot-study
#7
K Shiva Kumar, G N Hemanth, Poonam K Panjwani, Suraj Manjunath, Rakesh S Ramesh, Rajaram Burrah, Pritilata Rout, D Ramu, Elvis Peter Joseph, Ravi Chandran, C Prasad, Vipin Goel, Supari Divya
The axillary reverse mapping (ARM) technique has been described as an attempt to map and preserve the upper extremity lymphatic drainage during axillary lymph node dissection (ALND) and/or SLNB. This technique is based on the hypothesis that the lymphatic pathway from the upper extremity is not involved by metastasis from primary breast cancer. The ARM node/s however, has been found, in various studies, to be involved with metastatic foci in patients with extensive axillary lymph node metastases. Therefore, the oncological safety of this procedure has not yet been determined...
June 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28546526/molecular-signature-for-lymphatic-invasion-associated-with-survival-of-epithelial-ovarian-cancer
#8
E Sun Paik, Hyun Jin Choi, Tae-Joong Kim, Jeong-Won Lee, Byoung-Gie Kim, Duk-Soo Bae, Chel Hun Choi
Purpose: We aimed to develop molecular classifier that can predict lymphatic invasion and their clinical significance in epithelial ovarian cancer (EOC) patients. Materials and Methods: We analyzed gene expression (mRNA, methylated DNA) in data from The Cancer Genome Atlas. To identify molecular signatures for lymphatic invasion, we found differentially expressed genes. The performance of classifier was validated by receiver operating characteristics analysis, logistic regression, linear discriminant analysis (LDA), and support vector machine (SVM)...
May 22, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28545716/connective-tissue-growth-factor-regulates-fibrosis-associated-renal-lymphangiogenesis
#9
Hiroshi Kinashi, Lucas L Falke, Tri Q Nguyen, Niels Bovenschen, Jan Aten, Andrew Leask, Yasuhiko Ito, Roel Goldschmeding
Lymphangiogenesis is correlated with the degree of renal interstitial fibrosis. Pro-fibrotic transforming growth factor β induces VEGF-C production, the main driver of lymphangiogenesis. Connective tissue growth factor (CTGF) is an important determinant of fibrotic tissue remodeling, but its possible involvement in lymphangiogenesis has not been explored. We found prominent lymphangiogenesis during tubulointerstitial fibrosis to be associated with increased expression of CTGF and VEGF-C in human obstructed nephropathy as well as in diabetic kidney disease...
May 23, 2017: Kidney International
https://www.readbyqxmd.com/read/28545354/solid-lipid-nanoparticles-approach-for-lymphatic-targeting-through-intraduodenal-delivery-of-quetiapine-fumarate
#10
Mohd Yasir, Praveen Kumar Gaur, Dinesh Puri, Preeti Shekar, S Sadish Kumar
BACKGROUND: Lymphatic route is one of the prominent route for improving the poor bioavailability of the drugs which undergoes extensive hepatic first pass metabolism. Nanocarriers (solid lipid nanoparticles) offers a new drug delivery system that could hold great promise for attaining the bioavailability enhancement along with controlled and site specific drug delivery. OBJECTIVE: The aim of the present research work was to prepare and optimized the Quetiapine fumarate (an antipsychotic drug) loaded solid lipid nanoparticles for lymphatic targeting through intraduodenal administration Method: Thirteen quetiapine fumarate loaded solid lipid nanoparticle formulations were developed using different lipids by Microemulsion technique and optimized by box behnken design...
May 25, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/28544329/dissolving-microneedle-arrays-for-transdermal-delivery-of-amphiphilic-vaccines
#11
Myunggi An, Haipeng Liu
Amphiphilic vaccine based on lipid-polymer conjugates is a new type of vaccine capable of self-delivering to the immune system. When injected subcutaneously, amphiphilic vaccines efficiently target antigen presenting cells in the lymph nodes (LNs) via a unique albumin-mediated transport and uptake mechanism and induce potent humoral and cellular immune responses. However, whether this new type of vaccine can be administrated via a safe, convenient microneedle-based transdermal approach remains unstudied. For such skin barrier-disruption systems, a simple application of microneedle arrays (MNs) is desired to disrupt the stratum corneum, and for rapid and pain-free self-administration of vaccines into the skin, the anatomic place permeates with an intricate mesh of lymphatic vessels draining to LNs...
May 19, 2017: Small
https://www.readbyqxmd.com/read/28544031/ubiquitin-specific-protease-8-is-a-novel-prognostic-marker-in-early-stage-lung-adenocarcinoma
#12
Yunjung Kim, Aya Shiba-Ishii, Tomoki Nakagawa, Ryan Edbert Husni, Shingo Sakashita, Tomoyo Takeuchi, Masayuki Noguchi
Alterations of epidermal growth factor receptor (EGFR) expression frequently occur in early-stage lung adenocarcinoma. Ubiquitin-specific protease 8 (USP8) has been reported to stabilize EGFR protein at the plasma membrane through the recycling pathway. Here, we examined the correlation between USP8 expression and the expression or mutation status of EGFR, as well as the clinicopathological features of lung adenocarcinoma and patient outcome. Expression of EGFR and USP8 in surgically resected specimens of lung adenocarcinoma (82 cases) was examined by immunohistochemistry...
May 19, 2017: Pathology International
https://www.readbyqxmd.com/read/28543945/indirect-computed-tomography-lymphangiography-with-aqueous-contrast-for-evaluation-of-sentinel-lymph-nodes-in-dogs-with-tumors-of-the-head
#13
Janet A Grimes, Scott A Secrest, Nicole C Northrup, Corey F Saba, Chad W Schmiedt
Sentinel lymph node evaluation is widely used in human medicine to evaluate the first lymph node(s) to which a tumor drains. Sentinel lymph node biopsy allows avoidance of extensive lymphadenectomies in cases where the sentinel lymph node is negative for metastasis, thereby reducing patient morbidity. It has been shown that regional lymph nodes are not always the sentinel lymph node, thus identification and sampling of sentinel lymph nodes allows for more accurate staging, which is critical for treatment and prognostication in dogs with cancer...
May 21, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28543394/bullous-morphoea-a-retrospective-study
#14
M Venturi, A L Pinna, L Pilloni, L Atzori, C Ferreli, F Rongioletti
Bullous morphoea is a rare variant of localized scleroderma whose pathogenesis has been widely discussed. We retrospectively reviewed the records of all histopathologically confirmed cases of morphoea followed from 2005 to 2015 at the Dermatology Clinic and Pathology Institute of the University of Cagliari, Sardinia, Italy. Among 137 patients with morphoea, 2 cases of the bullous variant were identified, which were successfully treated with methotrexate. Thus, the bullous form comprised 1.4% of all cases of morphoea, which is much lower than the 7...
May 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28543381/ileocecal-vascularized-lymph-node-transfer-for-the-treatment-of-extremity-lymphedema-a-case-report
#15
Pedro Ciudad, Oscar J Manrique, Mouchammed Agko, En-Wei Liu, Wei-Ling Chang, Matthew Sze-Wei Yeo, Tony Chieh-Ting Huang, Ram M Chilgar, Hung-Chi Chen
Vascularized lymph node (VLN) transfer has been of high interest in the past decade for the treatment of lymphedema, since it has been shown to be effective in reducing limb volumes, decreasing infectious episodes and improving quality of life. Multiple donor sites have been described in the quest for the optimal one. Herein, we describe a novel lymph node flap option based on the ileocolic artery and vein. The ileocecal vascularized lymph node (IC-VLN) flap was used in the management of a 33-year-old male patient with lower extremity lymphedema secondary to left inguinal trauma...
May 24, 2017: Microsurgery
https://www.readbyqxmd.com/read/28543059/natural-pathology-of-the-captive-chimpanzee-pan-troglodytes-a-35-year-review
#16
REVIEW
Shyamesh Kumar, Hannah Laurence, Michael A Owston, R Mark Sharp, Priscilla Williams, Robert E Lanford, Gene B Hubbard, Edward J Dick
We present the spontaneous pathological lesions identified as a result of necropsy or biopsy for 245 chimpanzees (Pan troglodytes) over a 35-year period. A review of the pathology database was performed for all diagnoses on chimpanzees from 1980 to 2014. All morphologic diagnoses, associated system, organ, etiology, and demographic information were reviewed and analyzed. Cardiomyopathy was the most frequent lesion observed followed by hemosiderosis, hyperplasia, nematodiasis, edema, and hemorrhage. The most frequently affected systems were the gastrointestinal, cardiovascular, urogenital, respiratory, and lymphatic/hematopoietic systems...
May 23, 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/28543027/the-vascularized-groin-lymph-node-flap-vgln-anatomical-study-and-flap-planning-using-multi-detector-ct-scanner-the-golden-triangle-for-flap-harvesting
#17
Assaf A Zeltzer, Alexander Anzarut, Delphine Braeckmans, Katrin Seidenstuecker, Benoit Hendrickx, Eddy Van Hedent, Moustapha Hamdi
INTRODUCTION: A growing number of surgeons perform lymph node transfers for the treatment of lymphedema. When harvesting a vascularized lymph node groin flap (VGLNF) one of the major concerns is the potential risk of iatrogenic lymphedema of the donor-site. This article helps understanding of the lymph node distribution of the groin in order to minimize this risk. MATERIALS AND METHODS: Fifty consecutive patients undergoing abdominal mapping by multi-detector CT scanner were included and 100 groins analyzed...
May 25, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28542274/detecting-infection-hotspots-modeling-the-surveillance-challenge-for-elimination-of-lymphatic-filariasis
#18
Julie R Harris, Ryan E Wiegand
BACKGROUND: During the past 20 years, enormous efforts have been expended globally to eliminate lymphatic filariasis (LF) through mass drug administration (MDA). However, small endemic foci (microfoci) of LF may threaten the presumed inevitable decline of infections after MDA cessation. We conducted microsimulation modeling to assess the ability of different types of surveillance to identify microfoci in these settings. METHODS: Five or ten microfoci of radius 1, 2, or 3 km with infection marker prevalence (intensity) of 3, 6, or 10 times background prevalence were placed in spatial simulations, run in R Version 3...
May 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28542223/measuring-changes-in-transmission-of-neglected-tropical-diseases-malaria-and-enteric-pathogens-from-quantitative-antibody-levels
#19
Benjamin F Arnold, Mark J van der Laan, Alan E Hubbard, Cathy Steel, Joseph Kubofcik, Katy L Hamlin, Delynn M Moss, Thomas B Nutman, Jeffrey W Priest, Patrick J Lammie
BACKGROUND: Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. Analysis methods have predominantly maintained a single disease focus, yet integrated surveillance platforms would benefit from methodologies that work across diverse pathogens included in multiplex assays...
May 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28541637/prognostic-factors-and-treatment-outcomes-in-surgically-staged-non-invasive-uterine-clear-cell-carcinoma-a-turkish-gynecologic-oncology-group-study
#20
Mustafa Erkan Sarı, Mehmet Mutlu Meydanlı, Osman Türkmen, Günsü Kimyon Cömert, Ahmet Taner Turan, Alper Karalök, Hanifi Şahin, Ali Haberal, Eda Kocaman, Özgür Akbayır, Baki Erdem, Ceyhun Numanoğlu, Kemal Güngördük, Muzaffer Sancı, Mehmet Gökçü, Nejat Özgül, Mehmet Coşkun Salman, Gökhan Boyraz, Kunter Yüce, Tayfun Güngör, Salih Taşkın, Duygun Altın, Uğur Fırat Ortaç, Hülya Aydın Ayık, Tayup Şimşek, Macit Arvas, Ali Ayhan
OBJECTIVE: To assess the prognosis of surgically-staged non-invasive uterine clear cell carcinoma (UCCC), and to determine the role of adjuvant therapy. METHODS: A multicenter, retrospective department database review was performed to identify patients with UCCC who underwent surgical treatment between 1997 and 2016 at 8 Gynecologic Oncology Centers. Demographic, clinicopathological, and survival data were collected. RESULTS: A total of 232 women with UCCC were identified...
July 2017: Journal of Gynecologic Oncology
keyword
keyword
14986
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"