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https://www.readbyqxmd.com/read/28526046/balloon-versus-stenting-in-severe-ischaemia-of-the-leg-3-basil-3-study-protocol-for-a-randomised-controlled-trial
#1
Benjamin D Hunt, Matthew A Popplewell, Huw Davies, Lewis Meecham, Hugh Jarrett, Gareth Bate, Margaret Grant, Smitaa Patel, Catherine Hewitt, Lazaros Andronis, Jonathan J Deeks, Andrew Bradbury
BACKGROUND: Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial disease. The superficial femoral and popliteal arteries are the most commonly diseased vessels in such patients and are being increasingly treated using endovascular revascularisation techniques. However, it is currently unknown whether drug-eluting stents and drug-coated balloons confer additional clinical benefits over more established techniques using plain balloons and bare metal stents, or whether they represent a cost-effective use of NHS resources...
May 19, 2017: Trials
https://www.readbyqxmd.com/read/28523046/healthy-lifestyle-behavior-of-employees-in-small-and-medium-sized-enterprises-in-aydin-turkey
#2
Safiye Ozvurmaz, Aliye Mandiracioglu
OBJECTIVE: To determine healthy lifestyle behavior and affecting risk factors in workers at small and medium-sized enterprises from four different sectors in Aydin, Turkey. METHODS: This cross-sectional study was conducted at four different small and medium-sized enterprises in Aydin, Turkey and 264 employees participated in the study. A questionnaire was used for data collection. It consisted of questions about socio-demographic features (age, gender, marital status, education, perceived income, occupation and having children), health status, and medical history, medication use, having occupational accidents and occupational health and safety...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28511703/mindfulness-based-stress-reduction-for-people-with-multiple-sclerosis-a-feasibility-randomised-controlled-trial
#3
Robert Simpson, Frances S Mair, Stewart W Mercer
BACKGROUND: Multiple sclerosis (MS) is a stressful condition. Mental health comorbidity is common. Stress can increase the risk of depression, reduce quality of life (QOL), and possibly exacerbate disease activity in MS. Mindfulness-Based Stress Reduction (MBSR) may help, but has been little studied in MS, particularly among more disabled individuals. METHODS: The objective of this study was to test the feasibility and likely effectiveness of a standard MBSR course for people with MS...
May 16, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28510996/tramadol-with-or-without-paracetamol-acetaminophen-for-cancer-pain
#4
REVIEW
Philip J Wiffen, Sheena Derry, R Andrew Moore
BACKGROUND: Tramadol is an opioid analgesic licensed for use in moderate to severe pain. It is considered as a low risk for abuse, so control regulations are not as stringent as for 'strong' opioids such as morphine. It has a potential role as a step 2 option of the World Health Organization (WHO) analgesic ladder. OBJECTIVES: To assess the benefits and adverse effects of tramadol with or without paracetamol (acetaminophen) for cancer-related pain. SEARCH METHODS: We searched the following databases using a wide range of search terms: the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, and LILACS...
May 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28502846/domains-of-physical-activity-and-brain-volumes-a-population-based-study
#5
Carmen Jochem, Sebastian E Baumeister, Katharina Wittfeld, Michael F Leitzmann, Martin Bahls, Ulf Schminke, Marcello R P Markus, Stephan B Felix, Henry Völzke, Katrin Hegenscheid, Marcus Dörr, Hans Jörgen Grabe
Observational studies and intervention trials suggest that physical activity (PA) is beneficial for human brain morphology, especially in older individuals. Few population-based studies examined whether domain-specific PA is associated with brain volumes. Accordingly, we studied putative associations of PA during leisure time, sports and work with volumes of the hippocampus, the prefrontal cortex, the temporal lobe, gray matter (GM), white matter (WM) and total brain (TBV) after 5.9 years by applying volumetric analysis and voxel-based morphometry (VBM) with SPM 8/VBM 8 to brain magnetic resonance imaging data of 834 participants (447 women) aged 25 to 83 years from the population-based Study of Health in Pomerania...
May 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/28501651/severity-of-traumatic-injuries-predicting-psychological-outcomes-a-surprising-lack-of-empirical-evidence
#6
Adriel Boals, Zina Trost, Evan Rainey, Michael L Foreman, Ann Marie Warren
Despite widespread beliefs that trauma severity is related to levels of posttraumatic stress symptoms (PTSS), the empirical evidence to support such beliefs is lacking. In the current study we examined Injury Severity Score (ISS), a medical measure of event severity for physical injuries, in a sample of 460 patients admitted to a Level 1 Trauma Center. Results revealed no significant relationship between ISS and PTSS, depression, pain, and general physical and mental health at baseline, three months, and six months post-injury...
April 26, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28494024/household-food-security-and-adequacy-of-child-diet-in-the-food-insecure-region-north-in-ghana
#7
Pascal Agbadi, Helga Bjørnøy Urke, Maurice B Mittelmark
BACKGROUND AND OBJECTIVES: Adequate diet is of crucial importance for healthy child development. In food insecure areas of the world, the provision of adequate child diet is threatened in the many households that sometimes experience having no food at all to eat (household food insecurity). In the context of food insecure northern Ghana, this study investigated the relationship between level of household food security and achievement of recommended child diet as measured by WHO Infant and Young Child Feeding Indicators...
2017: PloS One
https://www.readbyqxmd.com/read/28490558/health-status-and-needs-of-cancer-survivors-attending-the-sydney-survivorship-centre-clinics-and-programmes-a-protocol-for-longitudinal-evaluation-of-the-centre-s-services
#8
Janette L Vardy, Cindy Tan, Jane D Turner, Haryana Dhillon
INTRODUCTION: The care of cancer survivors after primary adjuvant treatment is recognised as a distinct phase of the cancer journey. Recent research highlights the importance of lifestyle factors in treating symptoms, potentially decreasing risk of a cancer recurrence and modifying the risk of developing other chronic illnesses that are increased in the cancer population. Survivorship services aim to deliver care that addresses these issues. The overall aims are to determine the health status of cancer survivors and to evaluate the services offered by the Sydney Survivorship Centre (SSC)...
May 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28489920/a-national-study-of-the-molecular-epidemiology-of-hiv-1-in-australia-2005-2012
#9
Alison Castley, Shailendra Sawleshwarkar, Rick Varma, Belinda Herring, Kiran Thapa, Dominic Dwyer, Doris Chibo, Nam Nguyen, Karen Hawke, Rodney Ratcliff, Roger Garsia, Anthony Kelleher, David Nolan
INTRODUCTION: Rates of new HIV-1 diagnoses are increasing in Australia, with evidence of an increasing proportion of non-B HIV-1 subtypes reflecting a growing impact of migration and travel. The present study aims to define HIV-1 subtype diversity patterns and investigate possible HIV-1 transmission networks within Australia. METHODS: The Australian Molecular Epidemiology Network (AMEN) HIV collaborating sites in Western Australia, South Australia, Victoria, Queensland and western Sydney (New South Wales), provided baseline HIV-1 partial pol sequence, age and gender information for 4,873 patients who had genotypes performed during 2005-2012...
2017: PloS One
https://www.readbyqxmd.com/read/28483402/doxycycline-for-outpatient-treated-acute-exacerbations-of-copd-a-randomised-double-blind-placebo-controlled-trial
#10
Patricia van Velzen, Gerben Ter Riet, Paul Bresser, Jeroen J Baars, Bob T J van den Berg, Jan W K van den Berg, Paul Brinkman, Jennece W F Dagelet, Johannes M A Daniels, Dewi R G L Groeneveld-Tjiong, René E Jonkers, Coen van Kan, Frans H Krouwels, Karin Pool, Arjan Rudolphus, Peter J Sterk, Jan M Prins
BACKGROUND: Antibiotics do not reduce mortality or short-term treatment non-response in patients receiving treatment for acute exacerbations of COPD in an outpatient setting. However, the long-term effects of antibiotics are unknown. The aim of this study was to investigate if the antibiotic doxycycline added to the oral corticosteroid prednisolone prolongs time to next exacerbation in patients with COPD receiving treatment for an exacerbation in the outpatient setting. METHODS: In this randomised double-blind placebo-controlled trial, we recruited a cohort of patients with COPD from outpatient clinics of nine teaching hospitals and three primary care centres in the Netherlands...
May 5, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28482830/comparing-national-infectious-disease-surveillance-systems-china-and-the-netherlands
#11
Willemijn L Vlieg, Ewout B Fanoy, Liselotte van Asten, Xiaobo Liu, Jun Yang, Eva Pilot, Paul Bijkerk, Wim van der Hoek, Thomas Krafft, Marianne A van der Sande, Qi-Yong Liu
BACKGROUND: Risk assessment and early warning (RAEW) are essential components of any infectious disease surveillance system. In light of the International Health Regulations (IHR)(2005), this study compares the organisation of RAEW in China and the Netherlands. The respective approaches towards surveillance of arboviral disease and unexplained pneumonia were analysed to gain a better understanding of the RAEW mode of operation. This study may be used to explore options for further strengthening of global collaboration and timely detection and surveillance of infectious disease outbreaks...
May 8, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28481909/the-thyroid-cancer-policy-model-a-mathematical-simulation-model-of-papillary-thyroid-carcinoma-in-the-u-s-population
#12
Carrie Lubitz, Ayman Ali, Tiannan Zhan, Curtis Heberle, Craig White, Yasuhiro Ito, Akira Miyauchi, G Scott Gazelle, Chung Yin Kong, Chin Hur
BACKGROUND: Thyroid cancer affects over ½ million people in the U.S. and the incidence of thyroid cancer has increased worldwide at a rate higher than any other cancer, while survival has remained largely unchanged. The aim of this research was to develop, calibrate and verify a mathematical disease model to simulate the natural history of papillary thyroid cancer, which will serve as a platform to assess the effectiveness of clinical and cancer control interventions. METHODS: Herein, we modeled the natural pre-clinical course of both benign and malignant thyroid nodules with biologically relevant health states from normal to detected nodule...
2017: PloS One
https://www.readbyqxmd.com/read/28470413/sample-substitution-can-be-an-acceptable-data-collection-strategy-the-case-of-the-belgian-health-interview-survey
#13
Stefaan Demarest, Geert Molenberghs, Johan Van der Heyden, Lydia Gisle, Herman Van Oyen, Sandrine de Waleffe, Guido Van Hal
OBJECTIVES: Substitution of non-participating households is used in the Belgian Health Interview Survey (BHIS) as a method to obtain the predefined net sample size. Yet, possible effects of applying substitution on response rates and health estimates remain uncertain. In this article, the process of substitution with its impact on response rates and health estimates is assessed. METHODS: The response rates (RR)-both at household and individual level-according to the sampling criteria were calculated for each stage of the substitution process, together with the individual accrual rate (AR)...
May 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28464867/a-community-based-cluster-randomised-controlled-trial-to-evaluate-the-effectiveness-of-different-bundles-of-nutrition-specific-interventions-in-improving-mean-length-for-age-z-score-among-children-at-24%C3%A2-months-of-age-in-rural-bangladesh-study-protocol
#14
Sk Masum Billah, Tarana E Ferdous, Mohd Anisul Karim, Michael J Dibley, Shahreen Raihana, Md Moinuddin, Nuzhat Choudhury, Tahmeed Ahmed, D M Emdadul Hoque, Purnima Menon, Shams El Arifeen
BACKGROUND: Prevalence of stunting among under-five children in Bangladesh is 36%, varying with geographic and socio-economic characteristics. Previously, research groups statistically modelled the effect of 10 individual nutrition-specific interventions targeting the critical first 1000 days of life from conception, on lives saved and costs incurred in countries with the highest burden of stunted children. However, primary research on the combined effects of these interventions is limited...
May 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28462787/inspiratory-muscle-training-for-children-and-adolescents-with-neuromuscular-diseases-a-systematic-review
#15
REVIEW
Anri Human, Lieselotte Corten, Jennifer Jelsma, Brenda Morrow
Patients with neuromuscular diseases are at risk of morbidity and mortality due to respiratory compromise caused by respiratory muscle weakness. A systematic review was performed using pre-specified search strategies to determine the safety of inspiratory muscle training (IMT) and whether it has an impact on inspiratory muscle strength and endurance, exercise capacity, pulmonary function, dyspnoea and health-related quality of life. Randomised, quasi-randomised, cross-over and clinical controlled trials were included if they assessed the use of an external IMT device compared to no, sham/placebo, or alternative IMT treatment in children aged 5-18 years with neuromuscular diseases...
March 29, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28458473/screening-methods-clinical-breast-examination-and-mammography-to-detect-breast-cancer-in-women-aged-40-49-years
#16
Navneet Takkar, Suman Kochhar, Priyanka Garg, A K Pandey, Usha Rani Dalal, Uma Handa
OBJECTIVE: The aim of this study is to detect breast cancer rate, nodal status, tumor size, and associated risk factors using clinical breast examination (CBE) and mammography as screening tools in women aged 40-49 years. MATERIALS AND METHODS: A total of 500 women were screened in a time period of 2 years, between the ages of 40-49 years for breast cancer. Screening tools used were CBE and mammography. Clinical history and risk factors related to breast cancer were recorded...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28447363/tobacco-packaging-design-for-reducing-tobacco-use
#17
REVIEW
Ann McNeill, Shannon Gravely, Sara C Hitchman, Linda Bauld, David Hammond, Jamie Hartmann-Boyce
BACKGROUND: Tobacco use is the largest single preventable cause of death and disease worldwide. Standardised tobacco packaging is an intervention intended to reduce the promotional appeal of packs and can be defined as packaging with a uniform colour (and in some cases shape and size) with no logos or branding, apart from health warnings and other government-mandated information, and the brand name in a prescribed uniform font, colour and size. Australia was the first country to implement standardised tobacco packaging between October and December 2012, France implemented standardised tobacco packaging on 1 January 2017 and several other countries are implementing, or intending to implement, standardised tobacco packaging...
April 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28444695/exercise-therapy-for-chronic-fatigue-syndrome
#18
REVIEW
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price
BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem. Treatment may include physical interventions, such as exercise therapy, which was last reviewed in 2004. OBJECTIVES: The objective of this review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control...
April 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28443574/parents-attitudes-and-adherence-to-unintentional-injury-prevention-measures-in-ankara-turkey
#19
Tolga İnce, Songül Yalçın, Kadriye Yurdakök
BACKGROUND: Childhood unintentional injuries are being perceived as a leading public health issue since they are one of the preventable causes of pediatric mortality and morbidity. Whether and how parental factors related to childhood injury are searched insufficiently. So, understanding what parents do to prevent injuries, how well these prevention strategies work, and what encourages these actions is essential to decrease unintentional injury risk and to develop effective injury prevention strategies...
April 6, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28436583/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#20
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
April 24, 2017: Cochrane Database of Systematic Reviews
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