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Si-Cong Zhang, Shui-Hong Zhou, De-Sheng Shang, Yang-Yang Bao, Ling-Xiang Ruan, Ting-Ting Wu
The aim of the present study was to assess the role of diffusion-weighted magnetic resonance imaging (DWI) and apparent diffusion coefficient (ADC) values in hypopharyngeal carcinoma. A total of 40 hypopharyngeal carcinoma tissues and 15 benign lesion tissues were retrospectively analyzed. DWI, and T1- and T2-weighted magnetic resonance imaging (MRI) was performed. The sensitivity, specificity and accuracy of conventional MRI were 97.5, 66.7, and 89.1%, respectively. The mean ADC value [diffusion sensitive factor (b)=1,000× sec/mm2 ) for hypopharyngeal carcinomas was (1...
April 2018: Oncology Letters
Liangping Ni, Ying Liu
The present study aimed to assess early-stage nasopharyngeal carcinoma (NPC) with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) at 3.0 T. A total of 44 patients newly diagnosed with NPC were included in the present study. All patients underwent MR examination at 3.0 T using DCE-MRI and DWI. The volume transfer constant ( Ktrans ), flux rate constant between extravascular extracellular space and plasma ( Kep ), the volume of extravascular extracellular space per unit volume of tissue ( Ve ) and the apparent diffusion coefficient (ADC) of tumours were investigated...
April 2018: Oncology Letters
Tina D Kristensen, Rene C W Mandl, Jens R M Jepsen, Egill Rostrup, Louise B Glenthøj, Merete Nordentoft, Birte Y Glenthøj, Bjørn H Ebdrup
OBJECTIVE: Neuroplasticity is a well-described phenomenon, but effects of non-pharmacological interventions on white matter (WM) are unclear. Here we review associations between active non-pharmacological interventions and WM organization in healthy subjects and in psychiatric patients. METHOD: A systematic review of non-psychiatric and psychiatric studies in MEDLINE and EMBASE databases. We included longitudinal, controlled studies in human participants aged 18-60 years published in peer-reviewed journals between 2000 and 2017...
March 14, 2018: Neuroscience and Biobehavioral Reviews
Joanna Gariani, Olwen Westerland, Sarah Natas, Hema Verma, Gary Cook, Vicky Goh
OBJECTIVES: To undertake a systematic review to determine the diagnostic performance of whole body MRI (WBMRI) including diffusion weighted sequences (DWI) compared to whole body computed tomography (WBCT) or18 F-fluorodeoxyglucose positron emission tomography/CT (18 F-FDG PET/CT) in patients with myeloma. METHODS: Two researchers searched the primary literature independently for WBMRI studies of myeloma. Data were extracted focusing on the diagnostic ability of WBMRI versus WBCT and18 F-FDG PET/CT...
April 2018: Critical Reviews in Oncology/hematology
J D Santoro, N D Forkert, Q-Z Yang, S Pavitt, S J MacEachern, M E Moseley, K W Yeom
BACKGROUND AND PURPOSE: Tension-type and migraine-type headaches are the most common chronic paroxysmal disorders of childhood. The goal of this study was to compare regional cerebral volumes and diffusion in tension-type and migraine-type headaches against published controls. MATERIALS AND METHODS: Patients evaluated for tension-type or migraine-type headache without aura from May 2014 to July 2016 in a single center were retrospectively reviewed. Thirty-two patients with tension-type headache and 23 with migraine-type headache at an average of 4 months after diagnosis were enrolled...
March 15, 2018: AJNR. American Journal of Neuroradiology
Shotaro Kanao, Masako Kataoka, Mami Iima, Debra Masako Ikeda, Masakazu Toi, Kaori Togashi
OBJECTIVES: Benign and malignant inflammatory breast lesions demonstrate similar findings on both T2 weighted imaging (T2WI) and dynamic contrast enhanced (DCE) images. We hypothesized that benign inflammatory lesions might be differentiated form malignancies using a combination of apparent diffusion coefficient (ADC) values derived from diffusion weighted images (DWI) and T2WI. MATERIALS AND METHODS: We retrospectively reviewed 162 patients undergoing breast MRI (T2WI, DWI and DCE images) between 2008 and 2015 who had breast lesions with high T2WI signal intensity (High T2 SI) including 14 benign inflammatory lesions, 69 benign non-inflammatory lesions, 16 malignant inflammatory lesions and 63 malignant non-inflammatory lesions...
March 12, 2018: Magnetic Resonance Imaging
Dae-Hyun Kim, Deok-Soo Lee, Hyun-Wook Nah, Jae-Kwan Cha
BACKGROUND: A significant proportion of patients with mild ischemic stroke become disabled despite receiving intravenous thrombolytic therapy. The purpose of this study was to assess the clinical and radiological factors associated with unfavorable outcomes in patients with minor ischemic stroke that received intravenous recombinant tissue plasminogen activator (rt-PA) therapy. METHODS: We identified anterior circulation stroke patients with initial National Institutes of Health Stroke Scale (NIHSS) scores ≤5 who received intravenous thrombolysis within 4...
March 15, 2018: BMC Neurology
Katsuyuki Taguchi, Toshihide Itoh, Matthew K Fuld, Eric Fournie, Okkyun Lee, Kyo Noguchi
OBJECTIVES: A novel imaging technique ("X-map") has been developed to identify acute ischemic lesions for stroke patients using non-contrast-enhanced dual-energy computed tomography (NE-DE-CT). Using the 3-material decomposition technique, the original X-map ("X-map 1.0") eliminates fat and bone from the images, suppresses the gray matter (GM)-white matter (WM) tissue contrast, and makes signals of edema induced by severe ischemia easier to detect. The aim of this study was to address the following 2 problems with the X-map 1...
March 14, 2018: Investigative Radiology
Farah Averill, Thomas G Brown, Robyn D Robertson, Angeline Tchomgang, Djamal Berbiche, Louise Nadeau, Marie Claude Ouimet
OBJECTIVES: In a pilot randomised controlled trial of contingency management (CM) and transdermal alcohol monitoring (TAM) with driving while impaired by alcohol (DWI) offenders, perceptions regarding the acceptability of a TAM device, recruitment issues, and the impact of CM and TAM on alcohol use over a six-week period were evaluated. The results aimed to inform the design of future trials and programs involving CM and TAM for DWI remediation. METHODS: TAM devices were affixed to 37 voluntary, community-recruited male DWI offenders with problem alcohol use...
March 15, 2018: Traffic Injury Prevention
Evgeny J Chumin, Joaquín Goñi, Meredith E Halcomb, Timothy C Durazzo, Mario Džemidžić, Karmen K Yoder
BACKGROUND: Diffusion weighted imaging (DWI) has been widely used to investigate the integrity of white matter (WM; indexed by fractional anisotropy, FA) in alcohol dependence and cigarette smoking. These disorders are highly comorbid, yet cigarette use has often not been adequately controlled in neuroimaging studies of alcohol dependent populations. In addition, information on white matter deficits in currently drinking, nontreatment-seeking (NTS) individuals with alcohol dependence is limited...
March 15, 2018: Alcoholism, Clinical and Experimental Research
E V Aleksandrova, A I Batalov, E L Pogosbekyan, N E Zakharova, L M Fadeeva, A D Kravchuk, I N Pronin, A A Potapov
The study purpose was to develop a technique for intravital visualization of the brainstem reticular formation fibers in healthy volunteers using magnetic resonance imaging (MRI). MATERIAL AND METHODS: The study included 21 subjects (13 males and 8 females) aged 21 to 62 years. The study was performed on a magnetic resonance imaging scanner with a magnetic field strength of 3 T in T1, T2, T2-FLAIR, DWI, and SWI modes. A CSD-HARDI algorithm was used to identify thin intersecting fibers of the reticular formatio...
2018: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Yi Deng, Biran Yang, Yan Peng, Zhiqiang Liu, Jinwen Luo, Guoxin Du
OBJECTIVE: The purpose of the study was to examine differences in kidney intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) parameters in early-stage diabetic patients versus healthy controls. MATERIALS AND METHODS: Nineteen type 2 diabetic patients (group A) with a urinary albumin-to-creatinine ratio (ACR) < 30 mg/g and an estimated glomerular filtration rate (eGFR) of 80-120 mL/(min 1.73 m2 ) and twelve healthy volunteers (group B) were recruited...
March 14, 2018: Abdominal Radiology
Valeria Molinelli, Maria Gloria Angeretti, Ejona Duka, Nicola Tarallo, Elena Bracchi, Raffaele Novario, Carlo Fugazzola
PURPOSE: To evaluate whether the addition of gadolinium-enhanced MRI and diffusion-weighted imaging (DWI) improves T2 sequence performance for the diagnosis of local recurrence (LR) from rectal cancer and to assess which approach is better at formulating this diagnosis among readers with different experience. METHODS: Forty-three patients with suspected LR underwent pelvic MRI with T2 weighted (T2) sequences, gadolinium fat-suppressed T1 weighted sequences (post-contrast T1), and DWI sequences...
March 14, 2018: Abdominal Radiology
Muhammad I Alvi, Fatima Mubarak, Kumail Khandwala, Muhammad D Barakzai, Aisha Memon
Epidermoid cyst of the presacral space is a rare congenital lesion of ectodermal origin. Presacral epidermoid cysts have been previously reported in women, however are extremely rare in males. We report a case of presacral epidermoid cyst in a 55-year-old male who presented to our emergency department with acute urinary retention and history of chronic constipation. A non-contrast computed tomography scan was performed with suspicion of urolithiasis, which revealed a well circumscribed low attenuation presacral mass...
January 10, 2018: Curēus
Chuanjie Wu, Chuanhui Li, Wenbo Zhao, Nanchang Xie, Feng Yan, Yajun Lian, Li Zhou, Xiaoya Xu, Yong Liang, Lu Wang, Ming Ren, Sijie Li, Xuan Cheng, Lu Zhang, Qingfeng Ma, Haiqing Song, Ran Meng, Xunming Ji
OBJECTIVES: To investigate whether the plasma level of trimethylamine N -oxide (TMAO), a proatherosclerotic intestinal microbiota metabolite, can be a predictor of ischemic brain injury secondary to carotid artery stenting (CAS). METHODS: In this multicenter, prospective cohort study, we enrolled patients with severe carotid artery stenosis (>70%) who were prepared for CAS. Plasma TMAO level was measured within 3 days before CAS, and MRI was performed 1 to 3 days after CAS...
March 14, 2018: Neurology
Yossa Dwi Hartono, You Xu, Andrey Karshikoff, Lennart Nilsson, Alessandra Villa
The protonation states for nucleic acid bases are difficult to assess experimentally. In the context of triplex DNA, the protonation state of cytidine in the third strand is particularly important, because it needs to be protonated in order to form Hoogsteen hydrogen bonds. A sugar modification, locked nucleic acid (LNA), is widely used in triplex forming oligonucleotides to target sites in the human genome. In this study, the parameters for LNA are developed in line with the CHARMM nucleic acid force field and validated towards the available structural experimental data...
March 14, 2018: Journal of Chemical Information and Modeling
Pei-An Hu, Zheng-Rong Zhou
PURPOSES: Kaposiform hemangioendothelioma (KHE) is a unique locally aggressive vascular tumor with poor prognosis. The aim of this study is to assess the clinical and imaging features of KHE, and to compare the differences between solitary and diffusive infiltrative subtype further. METHODS: The clinical and radiological findings of a cohort of 25 cases with histologically proven KHE, between June 2011 and June 2016, were reviewed retrospectively. Seven solitary and 18 diffusive infiltrative subtypes KHE were included...
March 14, 2018: British Journal of Radiology
Thomas K F Foo, Evangelos Laskaris, Mark Vermilyea, Minfeng Xu, Paul Thompson, Gene Conte, Christopher Van Epps, Christopher Immer, Seung-Kyun Lee, Ek T Tan, Dominic Graziani, Jean-Baptise Mathieu, Christopher J Hardy, John F Schenck, Eric Fiveland, Wolfgang Stautner, Justin Ricci, Joseph Piel, Keith Park, Yihe Hua, Ye Bai, Alex Kagan, David Stanley, Paul T Weavers, Erin Gray, Yunhong Shu, Matthew A Frick, Norbert G Campeau, Joshua Trzasko, John Huston, Matt A Bernstein
PURPOSE: To build and evaluate a small-footprint, lightweight, high-performance 3T MRI scanner for advanced brain imaging with image quality that is equal to or better than conventional whole-body clinical 3T MRI scanners, while achieving substantial reductions in installation costs. METHODS: A conduction-cooled magnet was developed that uses less than 12 liters of liquid helium in a gas-charged sealed system, and standard NbTi wire, and weighs approximately 2000 kg...
March 13, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
S C Thust, S Heiland, A Falini, H R Jäger, A D Waldman, P C Sundgren, C Godi, V K Katsaros, A Ramos, N Bargallo, M W Vernooij, T Yousry, M Bendszus, M Smits
OBJECTIVES: At a European Society of Neuroradiology (ESNR) Annual Meeting 2015 workshop, commonalities in practice, current controversies and technical hurdles in glioma MRI were discussed. We aimed to formulate guidance on MRI of glioma and determine its feasibility, by seeking information on glioma imaging practices from the European Neuroradiology community. METHODS: Invitations to a structured survey were emailed to ESNR members (n=1,662) and associates (n=6,400), European national radiologists' societies and distributed via social media...
March 13, 2018: European Radiology
Qiang Zeng, Feina Shi, Jianmin Zhang, Chenhan Ling, Fei Dong, Biao Jiang
Purpose: To present a new modified tri-exponential model for diffusion-weighted imaging (DWI) to detect the strictly diffusion-limited compartment, and to compare it with the conventional bi- and tri-exponential models. Methods: Multi- b -value diffusion-weighted imaging (DWI) with 17 b -values up to 8,000 s/mm2 were performed on six volunteers. The corrected Akaike information criterions (AICc) and squared predicted errors (SPE) were calculated to compare these three models. Results: The mean f 0 values were ranging 11...
2018: Frontiers in Neuroscience
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