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https://www.readbyqxmd.com/read/29340725/decision-making-in-management-of-the-complex-trauma-patient-changing-the-mindset-of-the-non-trauma-surgeon
#1
Linda Sonesson, Kenneth Boffard, Lars Lundberg, Martin Rydmark, Klas Karlgren
BACKGROUND: European surgeons are frequently subspecialized and trained primarily in elective surgical techniques. As trauma leaders, they may occasionally have to deal with complex polytrauma, advanced management techniques, differing priorities, and the need for multidisciplinary care. There is a lack of expertise, experience, and a low trauma volume, as well as a lack of research, with limited support as to the decision-making and teaching challenges present. We studied what experienced trauma experts describe as the challenges that are specific to the advanced surgical decision-making required, whether civilian, humanitarian, or military...
January 16, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29339927/factors-affecting-the-cultural-competence-of-visiting-nurses-for-rural-multicultural-family-support-in-south-korea
#2
Min Hyun Suk, Won-Oak Oh, YeoJin Im
Background: With the recent growth of multicultural families in the Korean society, the importance of the role of qualified visiting nurses in the delivery of culturally sensitive health care has grown dramatically. As the primary health care provider for multicultural families enrolled in public community-based health care centers, the cultural competence of visiting nurses is an essential qualification for the provision of quality health care for multicultural families, especially in rural areas...
2018: BMC Nursing
https://www.readbyqxmd.com/read/29339746/zika-virus-in-salivary-glands-of-five-different-species-of-wild-caught-mosquitoes-from-mexico
#3
Darwin Elizondo-Quiroga, Aarón Medina-Sánchez, Jorge M Sánchez-González, Kristen Allison Eckert, Erendira Villalobos-Sánchez, Antonio Rigoberto Navarro-Zúñiga, Gustavo Sánchez-Tejeda, Fabián Correa-Morales, Cassandra González-Acosta, Carlos F Arias, Susana López, Rosa María Del Ángel, Victoria Pando-Robles, Armando E Elizondo-Quiroga
Zika virus (ZIKV) is a mosquito-borne pathogen, and Aedes aegypti has been identified as the main vector of the disease. Other mosquito species in the Aedes and Culex genera have been suggested to have the potential for being competent vectors based on experimental exposition of mosquitoes to an infectious blood meal containing ZIKV. Here, we report the isolation in cell culture of ZIKV obtained from different body parts of wild-caught female mosquitoes (Ae. aegypti, Ae. vexans, Cx. quinquefasciatus, Cx. coronator, and Cx...
January 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29339425/secondary-metabolism-and-interspecific-competition-affect-accumulation-of-spontaneous-mutants-in-the-gacs-gaca-regulatory-system-in-pseudomonas-protegens
#4
Qing Yan, Lucas D Lopes, Brenda T Shaffer, Teresa A Kidarsa, Oliver Vining, Benjamin Philmus, Chunxu Song, Virginia O Stockwell, Jos M Raaijmakers, Kerry L McPhail, Fernando D Andreote, Jeff H Chang, Joyce E Loper
Secondary metabolites are synthesized by many microorganisms and provide a fitness benefit in the presence of competitors and predators. Secondary metabolism also can be costly, as it shunts energy and intermediates from primary metabolism. In Pseudomonas spp., secondary metabolism is controlled by the GacS-GacA global regulatory system. Intriguingly, spontaneous mutations in gacS or gacA (Gac- mutants) are commonly observed in laboratory cultures. Here we investigated the role of secondary metabolism in the accumulation of Gac- mutants in Pseudomonas protegens strain Pf-5...
January 16, 2018: MBio
https://www.readbyqxmd.com/read/29338663/cultural-competency-in-dementia-care-an-african-american-case-study
#5
Jennie Leeder Clark, Sarah Phoenix, Ann Choryan Bilbrey, Terese McManis, Kristel Anne Escal, Rohini Arulanantham, Tiana Sisay, Rita Ghatak
Age is the greatest risk factor for Alzheimer's disease, the most common cause of dementia. The older population in the United States is growing, and within this demographic ethnic and racial diversity is also on the rise. This article introduces Stanford Health Care's Memory Support Program (MSP) as a model for culturally competent dementia care that spans inpatient and outpatient settings. The case study of an African American patient and family dealing with an Alzheimer's disease diagnosis and comorbid conditions is presented and explored to illustrate the MSP model...
December 26, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/29337662/studies-of-transgenic-mosquitoes-in-disease-endemic-countries-preparation-of-containment-facilities
#6
M Megan Quinlan, James Mutuku Mutunga, Abdoulaye Diabaté, Moussa Namountougou, Mamadou B Coulibaly, Lakamy Sylla, Jonathan Kayondo, Victor Balyesima, Lorna Clark, Mark Q Benedict, Peter Raymond
Novel approaches to area-wide control of vector species offer promise as additional tools in the fight against vectored diseases. Evaluation of transgenic insect strains aimed at field population control in disease-endemic countries may involve international partnerships and should be done in a stepwise approach, starting with studies in containment facilities. The preparations of both new-build and renovated facilities are described, including working with local and national regulations regarding land use, construction, and biosafety requirements, as well as international guidance to fill any gaps in regulation...
January 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29336921/legal-and-policy-issues-for-lgbt-patients-with-cancer-or-at-elevated-risk-of-cancer
#7
REVIEW
Sean R Cahill
OBJECTIVE: To understand the major legal and policy issues for lesbian, gay, bisexual and transgender (LGBT) cancer patients. DATA SOURCES: LGBT health policy research. CONCLUSION: Major policy issues include discrimination, lack of cultural competency and clinically appropriate care, insurance coverage, family recognition, and sexual orientation and gender identity data collection. IMPLICATIONS FOR NURSING PRACTICE: Nurses play a major role in providing affirming and competent care to LGBT cancer patients...
January 11, 2018: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/29336483/glucose-metabolism-during-in-vitro-maturation-of-mouse-oocytes-an-study-using-rna-interference
#8
Hong-Li Xie, Shuai Zhu, Jie Zhang, Jing Wen, Hong-Jie Yuan, Liu-Zhu Pan, Ming-Jiu Luo, Jing-He Tan
In previous studies on glucose metabolism during in vitro maturation, intact cumulus-oocyte complexes (COCs) were treated with enzyme inhibitors/activators. Because inhibitors/activators may have non-specificity and/or toxicity, and culture of COCs cannot differentiate whether glucose metabolism of cumulus cells (CCs) or that of the oocyte supports oocyte maturation, results from the previous studies must be verified by silencing genes in either CCs or cumulus-denuded oocytes (DOs). In this study, RNAi was adopted to specify the effects of glucose metabolism in CCs or DOs on oocyte maturation...
January 16, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29335809/healthcare-and-social-services-providers-who-serve-sexual-and-gender-minorities-in-a-u-s-mexico-border-city
#9
Oralia Loza, Carlos R Alvarez, David Peralta-Torres
Sexual and gender minorities, including lesbian, gay, bisexual, transgender, and queer (LGBTQ) individuals, experience barriers to healthcare as a result of stigma, discrimination, and poor cultural competence by healthcare and social services providers (HCSSP). The purpose of the study is to increase access to care and services for the LGBTQ community in a U.S.-Mexico border city by identifying LGBTQ-friendly HCSSP. A survey, developed based on concerns voiced in a predominantly Hispanic LGBTQ community, was administered to HCSSP and used to create a referral list, "The Purple Pages of El Paso" (PPoEP)...
January 15, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29335090/improving-the-efficacy-of-healthcare-services-for-aboriginal-australians
#10
Kylie Gwynne, Thomas Jeffries, Michelle Lincoln
Objective The aim of the present systematic review was to examine the enablers for effective health service delivery for Aboriginal Australians.Methods This systematic review was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Papers were included if they had data related to health services for Australian Aboriginal people and were published between 2000 and 2015. The 21 papers that met the inclusion criteria were assessed using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies...
January 16, 2018: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29334968/barriers-and-facilitators-to-cultural-competence-in-rehabilitation-services-a-scoping-review
#11
Viviane Grandpierre, Victoria Milloy, Lindsey Sikora, Elizabeth Fitzpatrick, Roanne Thomas, Beth Potter
BACKGROUND: There is an important need to evaluate whether rehabilitation services effectively address the needs of minority culture populations with North America's increasingly diverse population. The objective of this paper was therefore to review and assess the state of knowledge of barriers and facilitators to cultural competence in rehabilitation services. METHOD: Our scoping review focused on cultural competence in rehabilitation services. Rehabilitation services included in this review were: audiology, speech-language pathology, physiotherapy, and occupational therapy...
January 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29334763/long-non-coding-rna-linc01619-regulates-mir-27a-foxo1-and-endoplasmic-reticulum-stress-mediated-podocyte-injury-in-diabetic-nephropathy
#12
Xiaoyan Bai, Jian Geng, Xiao Li, Jiao Wan, Jixing Liu, Zhan Mei Zhou, Xiaoting Liu
AIMS: Altered activities of long non-coding RNAs (lncRNAs) have been implicated in the regulation of microRNAs. MicroRNA-27a (miR-27a) upregulation has been shown to induce endoplasmic reticulum stress (ER stress) and podocyte injury in diabetic nephropathy (DN). Herein, we aim to interrogate the mutually regulated network of miR-27a with long intergenic non-coding RNA 1619 (LINC01619) and the target gene. RESULTS: LINC01619 downregulation was found in human DN renal biopsy tissues and contributed to proteinuria and diminished renal function...
January 15, 2018: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29334397/recombinant-phosphatidylserine-binding-nanobodies-for-targeting-of-extracellular-vesicles-to-tumor-cells-a-plug-and-play-approach
#13
Sander A A Kooijmans, Jerney J J M Gitz-Francois, Raymond M Schiffelers, Pieter Vader
Extracellular vesicles (EVs) are increasingly being recognized as candidate drug delivery systems due to their ability to functionally transfer biological cargo between cells. However, manipulation of targeting properties of EVs through engineering of the producer cells can be challenging and time-consuming. As a novel approach to confer tumor targeting properties to isolated EVs, we generated recombinant fusion proteins of nanobodies against the epidermal growth factor receptor (EGFR) fused to phosphatidylserine (PS)-binding domains of lactadherin (C1C2)...
January 15, 2018: Nanoscale
https://www.readbyqxmd.com/read/29333058/acquisition-of-a-socially-learned-tool-use-sequence-in-chimpanzees-implications-for-cumulative-culture
#14
Gillian L Vale, Sarah J Davis, Susan P Lambeth, Steven J Schapiro, Andrew Whiten
Cumulative culture underpins humanity's enormous success as a species. Claims that other animals are incapable of cultural ratcheting are prevalent, but are founded on just a handful of empirical studies. Whether cumulative culture is unique to humans thus remains a controversial and understudied question that has far-reaching implications for our understanding of the evolution of this phenomenon. We investigated whether one of human's two closest living primate relatives, chimpanzees, are capable of a degree of cultural ratcheting by exposing captive populations to a novel juice extraction task...
September 2017: Evolution and Human Behavior: Official Journal of the Human Behavior and Evolution Society
https://www.readbyqxmd.com/read/29331828/a-recovery-time-after-warming-restores-mitochondrial-function-and-improves-developmental-competence-of-vitrified-ovine-oocytes
#15
Sara Succu, Sergio Domenico Gadau, Elisa Serra, Angelo Zinellu, Ciriaco Carru, Cristian Porcu, Salvatore Naitana, Fiammetta Berlinguer, Giovanni Giuseppe Leoni
The aim of the present study was to assess the ability of vitrified/warmed oocyte to recover from vitrification-induced damages after warming. In vitro matured, vitrified/warmed ovine oocytes were assessed for developmental competence, mitochondrial activity and distribution, ATP, ROS and catalase levels during 6 h of in vitro culture using fresh oocytes as control. ATP content in vitrified oocytes was lower than control during 4 h of post warming culture (p < .01). Vitrified oocytes were able to fill this gap only after 6 h of post-warming incubation...
December 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/29331637/development-of-a-multi-dimensional-scale-to-measure-trauma-associated-with-child-sexual-abuse-mscsa-and-its-ramifying-impacts-on-children-a-pilot-study
#16
Vandana Choudhary, Sujata Satapathy, Rajesh Sagar
BACKGROUND: With the rising incidence of CSA in India and absence of culturally competent tool to assess the impact of trauma, there is a dire need for development of a comprehensive scale to assess the impact of trauma on children. Thus, the present study aims to develop a multi-dimensional CSA tool for children aged between 7 and 13 years. METHOD: Qualitative research method of FGD/Key Interviews with 4 group participants (Parents, counsellors, mental health and medical professionals) and in-depth interview with children having history of CSA was conducted along with item pooling from existing scales...
January 4, 2018: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29329594/modelling-the-structure-of-a-cerna-theoretical-bipartite-microrna-mrna-interaction-network-regulating-intestinal-epithelial-cellular-pathways-using-r-programming
#17
J M Robinson, W A Henderson
OBJECTIVE: We report a method using functional-molecular databases and network modelling to identify hypothetical mRNA-miRNA interaction networks regulating intestinal epithelial barrier function. The model forms a data-analysis component of our cell culture experiments, which produce RNA expression data from Nanostring Technologies nCounter® system. The epithelial tight-junction (TJ) and actin cytoskeleton interact as molecular components of the intestinal epithelial barrier. Upstream regulation of TJ-cytoskeleton interaction is effected by the Rac/Rock/Rho signaling pathway and other associated pathways which may be activated or suppressed by extracellular signaling from growth factors, hormones, and immune receptors...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29325820/an-assessment-of-shedding-with-the-oral-rabies-virus-vaccine-strain-spbn-gasgas-in-target-and-non-target-species
#18
Ad Vos, Conrad Freuling, Steffen Ortmann, Antje Kretzschmar, Dietmar Mayer, Annette Schliephake, Thomas Müller
A safety requirement for live vaccines is investigating possible shedding in recipients since the presence of replication competent vaccine in secretions could result in direct and indirect horizontal transmission. This is especially relevant for oral rabies vaccine baits that are deliberately distributed into the environment. In the current study, survival of an oral rabies virus vaccine, SPBN GASGAS, was examined in excretions from different target and non-target species; red fox, raccoon dog, small Indian mongoose, raccoon, striped skunk, domestic dog, domestic cat and domestic pig...
January 8, 2018: Vaccine
https://www.readbyqxmd.com/read/29325817/cancer-screening-considerations-and-cancer-screening-uptake-for-lesbian-gay-bisexual-and-transgender-persons
#19
REVIEW
Marc Ceres, Gwendolyn P Quinn, Matthew Loscalzo, David Rice
OBJECTIVES: To describe the current state of cancer screening and uptake for lesbian, gay, bisexual, and transgender (LGBT) persons and to propose cancer screening considerations for LGBT persons. DATA SOURCES: Current and historic published literature on cancer screening and LGBT cancer screening; published national guidelines. CONCLUSION: Despite known cancer risks for members of the LGBT community, cancer screening rates are often low, and there are gaps in screening recommendations for LGBT persons...
January 8, 2018: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/29325816/lgbt-cultural-competence-and-interventions-to-help-oncology-nurses-and-other-health-care-providers
#20
REVIEW
Asa Radix, Shail Maingi
OBJECTIVES: To define and give an overview of the importance of lesbian, gay, bisexual, and transgender (LGBT) cultural competency and offer some initial steps on how to improve the quality of care provided by oncology nurses and other health care professionals. DATA SOURCES: A review of the existing literature on cultural competency. CONCLUSION: LGBT patients experience cancer and several other diseases at higher rates than the rest of the population...
January 8, 2018: Seminars in Oncology Nursing
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