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https://www.readbyqxmd.com/read/28508838/randomized-controlled-phase-iii-study-comparing-hepatic-arterial-infusion-with-systemic-chemotherapy-after-curative-resection-for-liver-metastasis-of-colorectal-carcinoma-jfmc-29-0003
#1
Mitsuo Kusano, Michitaka Honda, Koji Okabayashi, Koho Akimaru, Syuichi Kino, Yasushige Tsuji, Masashi Watanabe, Satoshi Suzuki, Takaki Yoshikawa, Junichi Sakamoto, Koji Oba, Shigetoyo Saji
BACKGROUND: The feasibility and efficacy of adjuvant hepatic arterial infusion (HAI) in preventing the development of liver metastases in patients with advanced colon carcinoma have not been validated. The aim of this randomized controlled study was to compare the feasibility of HAI and the protective effect against liver metastasis after curative resection to those of systemic chemotherapy. METHODS: Between July 2000 and June 2003, 91 patients were enrolled. Patients were randomly assigned to receive 5-fluorouracil (5-FU) via continuous venous infusion (CVI) or intra-hepatic arterial weekly high-dose 5-FU (WHF)...
January 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28503700/venous-ultrasonography-findings-and-clinical-correlations-in-104-thai-patients-with-chronic-venous-insufficiency-of-the-legs
#2
Burapa Kanchanabat, Waigoon Stapanavatr
INTRODUCTION: The pattern of venous reflux in Thai patients with chronic venous insufficiency (CVI) was studied in correlation with clinical manifestations. METHODS: Ultrasonography findings and clinical data were prospectively collected and retrospectively reviewed. RESULTS: CVI was found in 104 legs of 79 patients (mean age 59.8 ± 12.5 years; C4: 24.1%, C5: 8.9%; C6: 67.1%). Among 104 legs, 6.7% had history of deep vein thrombosis (DVT)...
May 15, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28490703/-construction-of-a-psychological-aging-scale-for-healthy-people
#3
Fei Lin, Yao Long, Ni Zeng, Lei Wu, Helang Huang
To construct a psychological aging scale, and to provide a tool and indexes for scientific evaluation on aging.
 Methods: The age-related psychological items were collected through literature screening and expert interview. The importance, feasibilityand the degree of authority for the psychological index system were graded by two rounds of Delphi method. Using analytic hierarchy process, the weight of dimensions and items were determined. The analysis for internal consistency reliability, correlation and exploratory factor was performed to evaluate the reliability and validity of the scales...
April 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28479317/biological-variation-of-platelet-parameters-determined-by-the-sysmex-xn-hematology-analyzer
#4
Sabrina Buoro, Michela Seghezzi, Barbara Manenti, Aurelio Pacioni, Anna Carobene, Ferruccio Ceriotti, Cosimo Ottomano, Giuseppe Lippi
BACKGROUND: This study was aimed to define the short- and medium-term biological variation (BV) estimates, the index of individuality and the reference change value (RCV) of platelet count, platelet distribution width, mean platelet volume, platelet larger cell ratio, plateletcrit and immature platelet fraction. METHODS: The study population consisted of 43 health subjects, who participated to the assessment of medium-term (21 subjects; blood sampling once a week for 5 consecutive weeks) and short-term (22 subjects; blood sampling once a day for 5 consecutive days) BV study, using Sysmex XN-module...
May 4, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28472140/validation-of-a-diabetes-numeracy-test-in-arabic
#5
Hussah Alghodaier, Hoda Jradi, Najwa Samantha Mohammad, Amen Bawazir
BACKGROUND: The prevalence of diabetes Mellitus in Saudi Arabia is 24%, ranking it among the top ten Worldwide. Diabetes education focuses on self-management and relies on numeracy skills. Poor numeracy may go unrecognized and it is important to have an assessment tool in Arabic to measure such a skill in diabetes care. OBJECTIVES: To validate a 15-item Diabetes Numeracy Test (DNT-15) in the Arabic Language as a tool to assess the numeracy skills of patients with diabetes and to test its properties among Saudi patients with diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28470942/influence-of-scanning-area-on-choroidal-vascularity-index-measurement-using-optical-coherence-tomography
#6
Rupesh Agrawal, Xin Wei, Abhilash Goud, Kiran Kumar Vupparaboina, Soumya Jana, Jay Chhablani
PURPOSE: Recently, choroidal vascularity index (CVI) is proposed as a novel tool to evaluate the choroidal vasculature. In this study, we investigate the impact of scanning area on CVI measurement using spectral-domain optical coherence tomography (SD-OCT). METHODS: Spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging mode was performed in 30 eyes from 15 normal subjects. Three scanning areas were compared: dingle foveal scan; central macular scans [scan passing through central 1000 microns circle on Early Treatment Diabetic Retinopathy Study (ETDRS) grid, inner circle]; and total macular cube scans...
May 4, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28461863/validation-of-medical-tourism-service-quality-questionnaire-mtsqq-for-iranian-hospitals
#7
Mohammad Qolipour, Amin Torabipour, Farzad Faraji Khiavi, Amal Saki Malehi
INTRODUCTION: Assessing service quality is one of the basic requirements to develop the medical tourism industry. There is no valid and reliable tool to measure service quality of medical tourism. This study aimed to determine the reliability and validity of a Persian version of medical tourism service quality questionnaire for Iranian hospitals. METHODS: To validate the medical tourism service quality questionnaire (MTSQQ), a cross-sectional study was conducted on 250 Iraqi patients referred to hospitals in Ahvaz (Iran) from 2015...
March 2017: Electronic Physician
https://www.readbyqxmd.com/read/28449360/biologic-variability-of-cardiac-troponin-i-in-healthy-dogs-and-dogs-with-different-stages-of-myxomatous-mitral-valve-disease-using-standard-and-high-sensitivity-immunoassays
#8
Randolph L Winter, Ashley B Saunders, Sonya G Gordon, Matthew W Miller, Geoffrey T Fosgate, Jan S Suchodolski, Jörg M Steiner
BACKGROUND: Biologic variability (BV) is one aspect of interpreting changes in biomarker concentrations known to be clinically important in people with cardiac disease, but it has not been adequately addressed in dogs so far. OBJECTIVES: The purpose of the study was to determine BV of cardiac troponin I (cTnI) in healthy dogs and dogs with 3 stages of myxomatous mitral valve disease (MMVD). METHODS: Healthy dogs and dogs with 3 stages of MMVD were prospectively assigned to groups based on comprehensive clinical evaluation using current guidelines...
April 27, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28446217/proximal-methylation-features-associated-with-nonrandom-changes-in-gene-body-methylation
#9
Colette L Picard, Mary Gehring
BACKGROUND: Gene body methylation at CG dinucleotides is a widely conserved feature of methylated genomes but remains poorly understood. The Arabidopsis thaliana strain Cvi has depleted gene body methylation relative to the reference strain Col. Here, we leverage this natural epigenetic difference to investigate gene body methylation stability. RESULTS: Recombinant inbred lines derived from Col and Cvi were used to examine the transmission of distinct gene body methylation states...
April 26, 2017: Genome Biology
https://www.readbyqxmd.com/read/28428356/biological-variation-estimates-obtained-from-91-healthy-study-participants-for-9-enzymes-in-serum
#10
Anna Carobene, Thomas Røraas, Una Ørvim Sølvik, Marit Sverresdotter Sylte, Sverre Sandberg, Elena Guerra, Irene Marino, Niels Jonker, Gerhard Barla, William A Bartlett, Pilar Fernandez-Calle, Jorge Díaz-Garzón, Francesca Tosato, Mario Plebani, Abdurrahman Coŝkun, Mustafa Serteser, Ibrahim Unsal, Ferruccio Ceriotti
BACKGROUND: We sought to develop estimates of biological variation (BV) for 9 enzymes in blood serum as part of the European Biological Variation Study. METHODS: Ninety-one healthy study participants (38 male and 53 female, 21-69 years old) were phlebotomized in each of 10 consecutive weeks at 6 European laboratories. The same preanalytical sample-handling protocol was followed at each center before transport to San Raffaele Hospital, Milan, Italy, for analysis...
April 20, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28420098/development-and-validation-of-a-questionnaire-to-assess-knowledge-threat-and-coping-appraisal-and-intention-to-practice-healthy-behaviors-related-to-non-communicable-diseases-in-the-thai-population
#11
Kanittha Chamroonsawasdi, Suthat Chottanapund, Pravich Tunyasitthisundhorn, Nawaphan Phokaewsuksa, Tassanee Ruksujarit, Pawarat Phasuksathaporn
Non-communicable diseases (NCDs) are important issues in Thailand and health sectors are now focusing on modifiable risks that include cognitive, affective and behavioral factors. This study aimed to develop and validate a questionnaire to assess knowledge about NCDs, threat appraisal, coping appraisal and intention to practice based on protection motivation theory. Content validity was determined by the mean of the item content validity index (I-CVI) from five experts. The questionnaire was pilot tested for difficulty of knowledge items and reliability test using the Kuder-Richardson (KR)-20 and Cronbach's alpha coefficient among 30 Thai adult subjects in the health office for two sub-districts...
April 14, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28403286/nursing-care-protocol-for-patients-with-a-ventricular-assist-device
#12
Regimar Carla Machado, Purificación Gironés, Andressa Rodrigues de Souza, Rita Simone Lopes Moreira, Camila Bomfim von Jakitsch, João Nelson Rodrigues Branco
OBJECTIVE: to develop and validate a nursing care protocol for patients with a ventricular assist device (VAD). METHOD: descriptive study, with a quantitative approach, for an instrument's methodological validation. Three stages were conducted: development of the instrument; protocol content validation according to the Delphi technique, and agreement among experts and the scientific literature. RESULTS: based on the content validation, a care protocol for patients with a VAD was created and assessed by Spanish experts...
April 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28403285/spanish-version-of-the-scale-of-attitudes-toward-alcohol-alcoholism-and-alcoholics-content-validation
#13
Erika Gisseth León Ramírez, Divane de Vargas, Luz Patrícia Diaz Heredia, Alejandra Sepúlveda Corzo
ABSTACT Objective: to describe the process of translation and cultural adaptation of the scale of attitudes towards alcohol, alcoholism and alcoholics into the Spanish language. METHODS: this was a methodological study, which followed the international guidelines for translation and adaptation of measurement scales. RESULTS: During the process of translation and cultural adaptation of scale of attitudes towards alcohol, alcoholism and alcoholics to the Spanish language, the items were adjusted based on semantic, idiomatic and conceptual equivalence of the expressions contained in the scale of attitudes towards alcohol, alcoholism and alcoholics...
April 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28396193/changing-medicare-utilization-of-minimally-invasive-procedures-for-the-treatment-of-chronic-venous-insufficiency
#14
Anand M Prabhakar, Alexander S Misono, Rahul A Sheth, Andrew B Rosenkrantz, Jennifer Hemingway, Danny R Hughes, Richard Duszak
PURPOSE: To examine changes in the utilization of procedures related to treatment of chronic venous insufficiency (CVI) in the Medicare population. MATERIALS AND METHODS: Service-specific claims data for phlebectomy, sclerotherapy, and radiofrequency (RF) and laser ablation were identified by using Medicare Physician Supplier Procedure Summary master files from 2005 through 2014. Longitudinal national utilization rates were calculated by using annual Medicare enrollment data from 2005 through 2013...
April 7, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28395706/accumulation-of-content-validation-evidence-for-the-critical-thinking-self-assessment-scale
#15
Girija Gopinathan Nair, Laurie-Ann M Hellsten, Lynnette Leeseberg Stamler
BACKGROUND/PURPOSE: Critical thinking skills (CTS) are essential for nurses; assessing students' acquisition of these skills is a mandate of nursing curricula. This study aimed to develop a self-assessment instrument of critical thinking skills (Critical Thinking Self-Assessment Scale [CTSAS]) for students' self-monitoring. METHODS: An initial pool of 196 items across 6 core cognitive skills and 16 subskills were generated using the American Philosophical Association definition of CTS...
April 1, 2017: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28391813/a-pc-based-shutter-glasses-controller-for-visual-stimulation-using-multithreading-in-labwindows-cvi
#16
Ivan Gramatikov, Kurt Simons, David Guyton, Boris Gramatikov
BACKGROUND AND OBJECTIVES: Amblyopia, commonly known as "lazy eye," is poor vision in an eye from prolonged neurologic suppression. It is a major public health problem, afflicting up to 3.6% of children, and will lead to lifelong visual impairment if not identified and treated in early childhood. Traditional treatment methods, such as occluding or penalizing the good eye with eye patches or blurring eye drops, do not always yield satisfactory results. Newer methods have emerged, based on liquid crystal shutter glasses that intermittently occlude the better eye, or alternately occlude the two eyes, thus stimulating vision in the "lazy" eye...
May 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28391615/choroidal-vascular-changes-in-age-related-macular-degeneration
#17
Lilian Hui Li Koh, Rupesh Agrawal, Neha Khandelwal, Labishetty Sai Charan, Jay Chhablani
PURPOSE: To assess the choroidal vascular changes using choroidal vascularity index (CVI) in patients with age-related macular degeneration (AMD) compared to controls. METHODS: Enhanced depth imaging (EDI) optical coherence tomography (OCT) scans of 64 patients with unilateral or bilateral AMD were obtained. Images with a poorly demarcated choroidal-scleral interface (CSI) were excluded from the analysis. Foveal scans of 63 AMD eyes and 35 'normal fellow' eyes were analysed...
April 9, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28382060/cultural-adaptation-and-psychometric-properties-of-the-persian-version-of-self-efficacy-in-chronic-disease-patients
#18
AhmadAli Eslami, Seyde-Sharbanoo Daniali, Karim Mohammadi, Negar Reisi-Dehkordi, Firoozeh Mostafavi-Darani
INTRODUCTION: Self-efficacy is an essential factor for effective self-management in chronic-disease patients. Therefore, the measurement of self-efficacy with a valid and reliable instrument is required. In this study, cultural adaptation and psychometric properties of the Persian version of "Self-Efficacy for Managing Chronic Disease" (SES6G) are illustrated in a sample of Iranian chronic-disease patients. MATERIALS AND METHODS: This was a cross-sectional study in which translation and backward translation was performed by bilingual translators...
January 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28380156/assessment-of-an-intervention-for-the-diffusion-of-evidence-based-nursing-in-a-teaching-hospital
#19
Fernanda Carolina Camargo, Helena Hemiko Iwamoto, Damiana Aparecida Trindade Monteiro, Lourraine Tavares Lorena, Gilberto de Araújo Pereira
Objective: To evaluate an intervention for the diffusion of evidence-based practice among the nurse leaders of a public teaching hospital. Methods: This is a descriptive-quantitative study based on the evaluation of workshops at a teaching hospital in the Triângulo Mineiro region of the state of Minas Gerais, Brazil, in 2016, conducted from the conceptual perspective of "Diffusion of Innovation and Skills for the Use of Evidence-Based Nursing in Care Settings"...
March 30, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28371403/visual-impairment-certification-due-to-diabetic-retinopathy-in-north-and-eastern-devon
#20
Siying Lin, Bhaskar Gupta, Natalee James, Roland H Ling
PURPOSE: To determine certifications of visual impairment (CVIs) due to diabetic retinopathy (DR) in a region that has operated diabetic screening since 1992. METHODS: A retrospective review of all CVIs due to DR was conducted, with mid-year population estimates and a diabetes prevalence model used to determine the annual incidence of certification from 2010 to 2013. For 2013, CVIs due to DR were also compared to all CVIs in the region. RESULTS: The total number of certifications due to DR was 75; 52 were sight impaired (SI) and 23 severely sight impaired (SSI) certifications; 25% of patients had type 1, and 75% had type 2 diabetes mellitus...
April 1, 2017: Acta Ophthalmologica
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