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REVIEW
Olga Reitblat, Eitan Livny, Irit Bahar
Corneal disease is among the leading reversible causes of blindness worldwide. Corneal transplantation is a successful and curative treatment for most of these cases. However, in certain indications it is not amendable for standard corneal transplantation, the only available option to restore functional vision is keratoprosthesis (KPro) implantation. KPros may also offer an alternative to the global shortage of donor corneas, limiting the access to transplantations. However, current KPros face many challenges, including surgical complexity that requires skilled surgeons and vast resources as well as unique surgical and post-operative complications...
May 2024: Harefuah
#2
JOURNAL ARTICLE
C Brockmeier, M B Borgstrøm, K Madsen, A Pinborg, N L Freiesleben, A Zedeler, M R Petersen, M L Grøndahl, P F Svendsen
STUDY QUESTION: Is there an association between the length of in vitro culture, mode of ART and the initial endogenous hCG rise, in cycles with a foetal heartbeat after single embryo transfer (ET) and implantation? SUMMARY ANSWER: Both the length of in vitro culture and the mode of ART have an impact on the initial endogenous rise in hCG in singleton pregnancies. WHAT IS KNOWN ALREADY: Different factors have been identified to alter the kinetics of hCG in pregnancies...
May 11, 2024: Human Reproduction
#3
JOURNAL ARTICLE
Huidi Shucheng, Xinyu Zhou, Dan Du, Jiaqi Li, Chenyang Yu, Xian Jiang
INTRODUCTION: The aim of this study was to assess the efficacy and safety of 15% azelaic acid (AzA) gel in treating acne-induced post-inflammatory erythema (PIE) and post-inflammatory hyperpigmentation (PIH). The effects of 15% AzA gel on acne, skin barrier function, and quality of life were also evaluated. METHODS: A total of 72 patients with mild to moderate acne were enrolled in a randomized, double-blind, placebo-controlled trial. Patients were divided into two groups: patients in the AzA group applied 15% AzA gel twice daily for 12 weeks, and those in the placebo group applied AzA-free gel...
May 11, 2024: Dermatology and Therapy
#4
REVIEW
Andrew J Hayes, Ioanna F Nixon, Dirk C Strauss, Beatrice M Seddon, Anant Desai, Charlotte Benson, Ian R Judson, Adam Dangoor
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location, means that developing evidence-based guidelines is complicated by the limitations of the data available. This makes it more important that STS are managed by expert multidisciplinary teams, to ensure consistent and optimal treatment, recruitment to clinical trials, and the ongoing accumulation of further data and knowledge. The development of appropriate guidance, by an experienced panel referring to the evidence available, is therefore a useful foundation on which to build progress in the field...
May 11, 2024: British Journal of Cancer
#5
JOURNAL ARTICLE
Mohamed Helmy, Yujun Liao, Zehao Zhao, Zhiqi Li, Kangmin He, Bin Xu
BACKGROUND: In bypass surgery for moyamoya disease (MMD), the superficial temporal artery's (STA) pressure needs to surpass that of the cortical M4 recipient of the middle cerebral artery (MCA), boosting cerebral blood flow into the MCA and enhancing cerebral circulation. This study investigates the STA-MCA arterial pressure parameters and gradients during bypass surgery, aiming to deepen our understanding of hemodynamic shifts pre- and post-operation. METHODS: DSA imaging data were prospectively collected from patients diagnosed with bilateral MMD who underwent STA-MCA bypass surgery between 2022 and 2023 and stratified according to the Suzuki stage...
May 12, 2024: Chinese Neurosurgical Journal
#6
JOURNAL ARTICLE
Christina L Schweitzer, Ivneet Garcha, Sam M Wiseman
BACKGROUND: This is the first study of Canadian thyroid and parathyroid surgery legal decisions, and the first study of surgical malpractice using the Canadian Legal Information Institute (CanLII) database. The objective was to identify quality improvement opportunities in surgical practice, to increase patient safety and satisfaction. METHODS: Legal decisions relating to thyroid and parathyroid surgery in the CanLII database were screened. Cases were included if a surgeon was listed as applicant or respondent; they related to pre-, intra-, or post-operative management of thyroid or parathyroid disease; and malpractice was alleged...
April 16, 2024: American Journal of Surgery
#7
JOURNAL ARTICLE
Patrycja Prokop, Marcin Bartoszewicz, Agnieszka Gardyszewska, Maciej Kosieradzki, Piotr Fiedor
Immunodeficiency predisposes to severe manifestations of human papillomavirus (HPV) infection, including extensive, recalcitrant anogenital lesions and their progression towards carcinomas. This holds for primary and acquired immunodeficiencies, and post-transplant immunosuppressive therapy. About 50% to 90% of patients receiving chronic immunosuppression after allogenic transplantation develop HPV-associated lesions within 4 to 5 years, comprising 10% to 15% of patients presenting with (pre)cancerous HPV-dependent anogenital lesions...
May 10, 2024: Transplantation Proceedings
#8
JOURNAL ARTICLE
Nidhisha Sadhwani, Santanu Kumar Bora, S Deepa, Varidh Katiyar, Amol Raheja, Ajay Garg, Vaishali Suri, Nikhil Tandon, Mehar Chand Sharma, Rajesh Khadgawat, Ashish Suri
OBJECTIVES: Endonasal endoscopic transsphenoidal surgery (TSS) and resection of pituitary adenomas is considered to be the gold standard treatment for Cushing's Disease (CD). Even with various recent advances in management, disease persistence and recurrences are common in these patients. The remission rate in the global population after surgery has been reported to vary widely from 64 to 93%. This study aims to determine various clinical, biochemical, radiological and histological factors that correlate with persistence and recurrence in patients with CD...
May 9, 2024: World Neurosurgery
#9
JOURNAL ARTICLE
Bartosz M Maciąg, Bartłomiej Wilk, Mateusz Nawrocki, Marcin Łapiński, Maciej Świercz, Krystian Żarnovsky, Olga Adamska, Artur Stolarczyk
BACKGROUND: Anterior knee pain (AKP) is one of the reasons for dissatisfaction after total knee replacement (TKR). It may result from patellofemoral joint dysfunction, caused by improper rotation of implant components. The aim of this study was to analyze patella positioning in patients after standard measured resection TKR and TKR with a use of a dynamic tensioner, and to assess the frequency of AKP, range of motion (ROM), and patient-reported outcome measures 6 weeks and 3 months postoperatively...
May 10, 2024: Knee
#10
JOURNAL ARTICLE
Erik Agustín Márquez-Gutiérrez, Luis Tamez-Pedroza, Ernesto Demian Morales-Naya, Mario Vélez-Palafox, Gerardo Cuartero-Castro, Noé Zacaula-Juárez, Roberto Sánchez-Sánchez, Maykel González-Torres
BACKGROUND: Ultrasound-assisted liposuction (UAL) has become popular because of its favorable outcomes in fat emulsification, blood loss reduction, and skin tightening. This study aimed to compare the effects of two UAL devices on the abdomen by assessing postsurgery skin biomechanical properties. METHODS: This single-blind, prospective study (2020-2022) involved 13 liposuction procedures performed on patients without chronic diseases. Each patient's abdomen was divided vertically from the xiphoid to the perineum...
April 25, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
#11
JOURNAL ARTICLE
Payton Kathryn Grande, David Hill, Jenessa McElfresh, Ram Velamuri, Xiangxia Liu
Biodegradable Temporizing Matrix (BTM) is a synthetic dermal template recently developed to reconstruct complex wounds. Current literature describes BTM outcomes in the presence of infection and other comorbidities but are limited by small sample sizes. The purpose of this systemic review and meta-analysis was to determine current breadth and success of BTM use for complex wound closure. Databases were searched to identify previously published studies describing BTM use in human wounds. Studies were excluded if conducted in vitro, using non-human animals, or for procedures irrelevant to wound care...
May 11, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
#12
JOURNAL ARTICLE
Alexandra R Stewart, Stephen W Olson, Brent L Lechner, Maura A Watson, Christina M Yuan, Robert Nee
PURPOSE: To evaluate the impact of surgical intervention on long-term renal outcomes for adult patients with congenital ureteropelvic junction obstruction (UPJO). METHODS: We queried service members diagnosed with UPJO from the United States Military Health System electronic health records from 2005 to 2020. We assessed demographic, laboratory, radiology, surgical intervention, and outcome data. We evaluated the impact of surgical intervention on renal function based on the estimated glomerular filtration rate (eGFR), hypertension (HTN, defined as any prescription for blood pressure [BP] medication and/or average of two BP readings ≥ 130/80 mmHg more than 2 weeks apart), and changes in renal excretory function on radionuclide scans...
May 11, 2024: International Urology and Nephrology
#13
JOURNAL ARTICLE
Kenji Matsumoto, Hiroharu Shinozaki, Satoshi Shinozaki, Seigo Yukisawa, Masaru Kimata, Toshiaki Terauchi, Naohiro Sata
BACKGROUND AND OBJECTIVES: Median arcuate ligament syndrome is caused by compression and stenosis of the celiac artery. Incision of the median arcuate ligament improves persistent abdominal symptoms. The study aimed at evaluating the outcomes in patients who underwent median arcuate ligament syndrome decompression using a self-report questionnaire. METHODS: This single-center retrospective study included patients with median arcuate ligament syndrome who underwent decompression surgery between April 2021 and February 2023...
May 11, 2024: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
#14
REVIEW
Samah Morsi, Marisabel Linares Bolsegui, Hassan Kobeissi, Sherief Ghozy, David F Kallmes, Scott R Kelley, Kellie L Mathis, Eric J Dozois, Conor G Loftus, Emily C Bendel, Vincent Vidal, Scott M Thompson
BACKGROUND: Internal hemorrhoids (IH) is a common medical condition that can result in morbidity secondary to bleeding and discomfort. Treatment for IH has traditionally consisted of dietary and conservative medical management, focal treatments including banding and sclerotherapy or hemorrhoidectomy. Recently, rectal artery embolization (RAE) has been studied as a potential treatment for bleeding predominant IH. We performed a common design and data element analysis of studies that report on RAE...
May 11, 2024: CVIR Endovascular
#15
JOURNAL ARTICLE
Carlos Abril-Pérez, Miguel Mansilla-Polo, Begoña Escutia-Muñoz, Onofre Sanmartín, Joan R Garcés, Manuel A Rodríguez-Prieto, Verónica Ruiz-Salas, Esther de Eusebio-Murillo, Román Miñano-Medrano, Beatriz González-Sixto, Juan L Artola-Igarza, Alberto Alfaro-Rubio, Pedro Redondo, Yolanda Delgado-Jiménez, Julia M Sánchez-Schmidt, Irati Allende-Markixana, María L Alonso-Pacheco, Beatriz García-Bracamonte, Pablo de la Cueva-Dobao, Raquel Navarro-Tejedor, Cristina Ciudad-Blanco, Lucía Carnero-González, Hugo Vázquez-Veiga, Natividad Cano-Martínez, Carlos Serra-Guillén, Eva Vilarrasa, Pedro Sánchez-Sambucety, José L López-Estebaranz, Ángeles Flórez-Menéndez, Antonio Martorell-Calatayud, Pilar Gil, Victoriano Morales-Gordillo, Agustí Toll, Izascun Ocerin-Guerra, Matías Mayor-Arenal, Ricardo Suárez-Fernández, Laura Sainz-Gaspar, Miguel A Descalzo, Ignacio Garcia-Doval, Rafael Botella-Estrada
BACKGROUND: Immunosuppressed (IS) patients, particularly solid organ transplant recipients and those on immunosuppressive therapy, face a higher incidence and recurrence of nonmelanoma skin cancers (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Mohs micrographic surgery (MMS) is the preferred treatment for high-risk NMSC due to its high cure rate and margin examination capabilities. However, IS patients may experience more complications, such as surgical site infections, and a greater risk of recurrence, making their outcomes a subject of interest...
May 11, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#16
JOURNAL ARTICLE
Laia Maynou, Alistair McGuire, Victoria Serra-Sastre
This paper examines the effect of new medical technology (robotic surgery) on efficiency gains and productivity changes for surgical treatment in patients with prostate cancer from the perspective of a public health sector organization. In particular, we consider three interrelated surgical technologies within the English National Health System: robotic, laparoscopic and open radical prostatectomy. Robotic and laparoscopic techniques are minimally invasive procedures with similar clinical benefits. While the clinical benefits in adopting robotic surgery over laparoscopic intervention are unproven, it requires a high initial investment cost and carries high on-going maintenance costs...
May 11, 2024: Health Economics
#17
JOURNAL ARTICLE
Lauren Gyemi, Asher Selznick, Brad Petrisor, Michelle Ghert
PURPOSE: The primary objective of this study was to determine time to full weight-bearing after the use of a calcium-sulfate-calcium phosphate bone substitute (CaSO4/CaPO4) as a bone void filler in the treatment of primary benign bone tumours following intralesional curettage. The secondary objectives were to determine surgical complications and recurrence rates. METHODS: Retrospective review of patients identified from a surgeon-specific orthopaedic oncology database, who underwent curettage of benign bone tumours and subsequent bone void filling with CaSO4/CaPO4...
2024: Journal of Orthopaedic Surgery
#18
JOURNAL ARTICLE
Mary E Phillips, M Denise Robertson, Kate Bennett-Eastley, Lily Rowe, Adam E Frampton, Kathryn H Hart
BACKGROUND AND METHODS: Pancreatico-duodenectomy (PD) carries significant morbidity and mortality, with very few modifiable risk factors. Radiological evidence of sarcopenia is associated with poor outcomes. This retrospective study aimed to analyse the relationship between easy-to-use bedside nutritional assessment techniques and radiological markers of muscle loss to identify those patients most likely to benefit from prehabilitation. RESULTS: Data were available in 184 consecutive patients undergoing PD...
April 25, 2024: Nutrients
#19
JOURNAL ARTICLE
Ionela Mihai, Horatiu Dura, Cosmin Adrian Teodoru, Samuel Bogdan Todor, Cristian Ichim, Nicolae Grigore, Cosmin Ioan Mohor, Alin Mihetiu, George Oprinca, Nicolae Bacalbasa, Denisa Tanasescu, Dan Georgian Bratu, Adrian Boicean, Bogdan Oros, Adrian Hasegan
The use of 3D laparoscopic partial nephrectomy has emerged as a cornerstone in the surgical arsenal for addressing renal tumors, particularly in managing challenging cases characterized by deeply seated tumors embedded within the renal parenchyma. In these intricate scenarios, the utilization of intraoperative ultrasound (IOUS) acquires paramount importance, serving as an indispensable tool for guiding and meticulously monitoring the surgical process in real time. To further explore the efficacy of IOUS-guided techniques, we conducted a retrospective study comparing outcomes in patients who underwent partial nephrectomy with IOUS guidance ( n = 60) between 2020 and 2022 with a cohort from 2018 to 2019 without IOUS guidance ( n = 25)...
April 30, 2024: Diagnostics
#20
JOURNAL ARTICLE
Marius Bogdan Novac, Lidia Boldeanu, Anda Lorena Dijmărescu, Mihail Virgil Boldeanu, Simona Daniela Neamțu, Lucreţiu Radu, Maria Magdalena Manolea, Mircea-Sebastian Șerbănescu, Maria Stoica, Luciana Teodora Rotaru, Constantin-Cristian Văduva
A weakened immune system and more inflammatory cytokines being released are possible effects of the surgical stress that a cesarean section induces. This kind of reaction, in addition to the altered reaction to catecholamines, has the potential to significantly affect the immune system of the mother and the patients' general postoperative course. This prospective study compared the plasma levels of catecholamines and cytokines in healthy pregnant patients having cesarean sections under spinal anesthesia versus general anesthesia...
April 24, 2024: Diagnostics
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