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https://www.readbyqxmd.com/read/28688564/utility-of-intraoperative-and-postoperative-radiographs-in-pediatric-cochlear-implant-surgery
#1
Samantha Anne, Jose Miguel Juarez, Amber Shaffer, David Eleff, Dennis Kitsko, Sarah Sydlowski, Erika Woodson, David Chi
OBJECTIVE: Routine plain film radiographs are often obtained to confirm proper placement of electrode after pediatric cochlear implant surgery. Objective is to evaluate necessity of routine radiographs in pediatric cochlear implant cases. STUDY DESIGN: Retrospective review. SETTING: Two tertiary care academic centers. SUBJECTS AND METHODS: Review of all children that underwent cochlear implantation from January 2003 thru June 2015...
August 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28683262/untangling-the-neural-circuits-for-sexual-behavior
#2
Jonathan Woodson, Addison Niemeyer, Joseph Bergan
In this issue, Ishii and colleagues identify an anatomically and genetically defined circuit by which a single compound, exocrine gland-secreted peptide-1 (ESP1), enhances reproductive behavior in female mice.
July 5, 2017: Neuron
https://www.readbyqxmd.com/read/28681961/technical-tips-during-implantation-of-selective-upper-airway-stimulation
#3
Clemens Heiser, Erica Thaler, Ryan J Soose, B Tucker Woodson, Maurits Boon
OBJECTIVE: Selective upper airway stimulation is now well-established in the United States and in several European countries, with more than 1,000 patients implanted since U.S. Food and Drug Administration approval in April 2014. The authors herein, all head and neck surgeons, account for approximately one of every five implants completed to date. Several of the authors also provide comprehensive longitudinal care of their patients as dual-specialty sleep medicine physicians. STUDY DESIGN: Multi-center, retrospective clinical analysis...
July 6, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28632384/finite-field-method-for-nonlinear-optical-property-prediction-using-rational-function-approximants
#4
Anand H G Patel, Ahmed A K Mohammed, Peter A Limacher, Paul W Ayers
The finite field (FF) method is a quick, easy-to-implement tool for the prediction of nonlinear optical properties. Here, we present and explore a novel variant of the FF method, which uses a rational function to fit a molecule's energy with respect to an electric field. Similarly to previous FF methods, factors crucial for the method's accuracy were tuned. These factors include the number of terms in the function, the distribution of fields used to construct the approximation, and the initial field in the approximation...
July 6, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28632078/-less-than-a-vapor-positioning-black-lesbian-women-in-history-teacher-education
#5
Ashley N Woodson
In this article, I discuss the possibilities and implications of centering Black lesbian identities and relationships in history teacher education through a case study with one straight Black woman preservice history teacher named Danitra. Danitra's understanding and navigation of historical research on Black lesbians are discussed in relation to core themes of lesbian historiography and emancipatory historiography. Though the literature on this group is limited, I argue that critical considerations of Black lesbians' interests and experiences help educators to conceive of and teach about history, citizenship, justice, and sexuality in more liberatory ways...
September 22, 2016: Journal of Lesbian Studies
https://www.readbyqxmd.com/read/28596260/evaluating-the-nccn-clinical-criteria-for-recommending-brca1-and-brca2-genetic-testing-in-patients-with-breast-cancer
#6
Caiqian Cropper, Ashley Woodson, Banu Arun, Carlos Barcenas, Jennifer Litton, Sarah Noblin, Diane Liu, Minjeong Park, Molly Daniels
Background: Mutations in the BRCA1 and BRCA2 genes predispose individuals to a significantly elevated risk for breast and ovarian cancers. Identification of these individuals allows for proper screening, management, and testing of at-risk relatives. NCCN has established clinical criteria for recommending BRCA1/2 testing. Patients and Methods: A retrospective chart review of 1,123 patients with breast cancer was performed to evaluate the positive predictive values (PPVs) of 14 individual criteria for predicting BRCA1/2 mutations...
June 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28595273/acupuncture-therapy-in-a-group-setting-for-chronic-pain
#7
Benjamin Kligler, Arya Nielsen, Corinne Kohrrer, Tracy Schmid, Eve Waltermaurer, Elidania Perez, Woodson Merrell
Objective.:  This project was designed to test the feasibility and effectiveness of acupuncture therapy given in a group setting for chronic pain. Design.:  Nonrandomized, repeated measures quasi-experimental trial. Setting.:  Care was delivered in a primary care clinic waiting area after clinic hours. Subjects.:  Included were primary care patients (≥18 years old) with chronic pain of the neck, back, shoulder, or osteoarthritis of any site of at least three months' duration...
June 8, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28578544/effects-of-minimal-versus-intensive-intervention-to-enhance-motivational-interviewing-in-hiv-care
#8
Mary Catherine Beach, M Barton Laws, Gary Rose, Debra Roter, Yoojin Lee, Geetanjali Chander, Tanita Woodson, Richard D Moore, William Rogers, Ira B Wilson
We conducted a randomized trial comparing the effect of two different levels of motivational interviewing training on clinician communication behaviors and patient experiences. We enrolled 12 HIV clinicians who attended a one-day MI workshop focusing on behavior change counseling skills. We then randomized clinicians to receive (or not) 3-5 rounds of personalized feedback from the MI trainer. We compared outcomes before and after the interventions and between the intervention groups. We tested time-by-study arm interactions to determine if one group improved more than the other...
June 3, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28562608/correction-active-zone-proteins-are-transported-via-distinct-mechanisms-regulated-by-par-1-kinase
#9
Kara R Barber, Julia Tanquary, Keegan Bush, Amanda Shaw, Michael Woodson, Karthikeyan Tangavelou, Michael Sherman, Yogesh P Wairkar
[This corrects the article DOI: 10.1371/journal.pgen.1006621.].
May 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28522763/aortic-arch-compliance-and-idiopathic-unilateral-vocal-fold-paralysis
#10
Reza Behkam, Kara E Roberts, Andrew J Bierhals, M Eileen Jacobs, Julia D Edgar, Randal C Paniello, Gayle Woodson, Jonathan P Vande Geest, Julie M Barkmeier-Kraemer
Unilateral vocal fold paralysis (UVP) occurs related to recurrent laryngeal nerve (RLN) impairment associated with impaired swallowing, voice production, and breathing functions. The majority of UVP cases occur subsequent to surgical intervention with approximately 12-42% having no known cause for the disease (i.e., idiopathic). Approximately 2/3 of those with UVP exhibit left-sided injury with the average onset at 50 years of age or older in those diagnosed as idiopathic. Given the association between the RLN and the subclavian and aortic arch vessels, we hypothesized that changes in vascular tissues would result in increased aortic compliance in idiopathic left-sided UVP patients compared to those without UVP...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28469298/where-are-we-with-bladder-preservation-for-muscle-invasive-bladder-cancer-in-2017
#11
REVIEW
Woodson Wade Smelser, Marcus A Austenfeld, Jeffrey Maxwell Holzbeierlein, Eugene Kang Lee
INTRODUCTION: In 2017, neoadjuvant, cisplatin-based chemotherapy followed by radical cystectomy (RC) is considered the gold standard therapy for muscle-invasive bladder based on randomized controlled trials. Across all tumor stages, this approach has been associated with the highest rates of disease-specific survival. However, RC is one of the most challenging procedures performed by urologic surgeons and carries with it significant risks of complications, hospital readmission, and even a small risk of mortality, in addition to lifestyle changes that can have long-term effects on well-being...
April 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28442428/rapamycin-modulation-of-p70-s6-kinase-signaling-inhibits-rift-valley-fever-virus-pathogenesis
#12
Todd M Bell, Virginia Espina, Svetlana Senina, Caitlin Woodson, Ashwini Brahms, Brian Carey, Shih-Chao Lin, Lindsay Lundberg, Chelsea Pinkham, Alan Baer, Claudius Mueller, Elizabeth A Chlipala, Faye Sharman, Cynthia de la Fuente, Lance Liotta, Kylene Kehn-Hall
Despite over 60 years of research on antiviral drugs, very few are FDA approved to treat acute viral infections. Rift Valley fever virus (RVFV), an arthropod borne virus that causes hemorrhagic fever in severe cases, currently lacks effective treatments. Existing as obligate intracellular parasites, viruses have evolved to manipulate host cell signaling pathways to meet their replication needs. Specifically, translation modulation is often necessary for viruses to establish infection in their host. Here we demonstrated phosphorylation of p70 S6 kinase, S6 ribosomal protein, and eIF4G following RVFV infection in vitro through western blot analysis and in a mouse model of infection through reverse phase protein microarrays (RPPA)...
July 2017: Antiviral Research
https://www.readbyqxmd.com/read/28425611/a-simple-assessment-tool-for-evaluation-of-cadaveric-temporal-bone-dissection
#13
Sarah E Mowry, Erika Woodson, Samuel Gubbels, Matt Carfrae, Marlan R Hansen
EDUCATIONAL OBJECTIVE: Objective metrics in skilled-based educational courses allow trainees and instructors to assess performance and monitor progress. The objective is to validate a concise, easy-to-use instrument for assessment of resident skill during a timed cadaveric temporal-bone (CTB) dissection. STUDY DESIGN: Retrospective analysis. METHODS: An instrument was developed to assess resident performance on a yearly timed microdissection of CTB...
April 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28389592/cutting-edge-selective-oral-rock2-inhibitor-reduces-clinical-scores-in-patients-with-psoriasis-vulgaris-and-normalizes-skin-pathology-via-concurrent-regulation-of-il-17-and-il-10
#14
Alexandra Zanin-Zhorov, Jonathan M Weiss, Alissa Trzeciak, Wei Chen, Jingya Zhang, Melanie S Nyuydzefe, Carmen Arencibia, Seetharam Polimera, Olivier Schueller, Judilyn Fuentes-Duculan, Kathleen M Bonifacio, Norma Kunjravia, Inna Cueto, Jennifer Soung, Roy M Fleischmann, Alan Kivitz, Mark Lebwohl, Margarita Nunez, Johnnie Woodson, Shondra L Smith, Robert F West, Mark Berger, James G Krueger, John L Ryan, Samuel D Waksal
Targeted inhibition of Rho-associated kinase (ROCK)2 downregulates the proinflammatory T cell response while increasing the regulatory arm of the immune response in animals models of autoimmunity and Th17-skewing human cell culture in vitro. In this study, we report that oral administration of a selective ROCK2 inhibitor, KD025, reduces psoriasis area and severity index scores by 50% from baseline in 46% of patients with psoriasis vulgaris, and it decreases epidermal thickness as well as T cell infiltration in the skin...
May 15, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28351995/sirt6-deficiency-results-in-progression-of-glomerular-injury-in-the-kidney
#15
Wen Huang, Hua Liu, Shuang Zhu, Michael Woodson, Rong Liu, Ronald G Tilton, Jordan D Miller, Wenbo Zhang
Aging is associated with an increased incidence and prevalence of renal glomerular diseases. Sirtuin (Sirt) 6, a nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase, has been shown to protect against multiple age-associated phenotypes; however it is unknown whether Sirt6 has a direct pathophysiologic role in the kidney. In the present study, we demonstrate that Sirt6 is expressed in the kidney and aging Sirt6-deficient mice exhibit renal hypertrophy with glomerular enlargement. Sirt6 deletion induces podocyte injury, including decreases in slit diaphragm proteins, foot process effacement, and cellular loss, resulting in proteinuria...
March 28, 2017: Aging
https://www.readbyqxmd.com/read/28348599/a-rare-case-of-stroke-secondary-to-iron-deficiency-anemia-in-a-young-female-patient
#16
Kavitha Gopalratnam, Kevin Andrew Woodson, Jigarkumar Rangunwala, Kanaga Sena, Manisha Gupta
Ischemic strokes occur when there is a sudden obstruction of an artery supplying blood flow to an area of the brain, leading to a focal neurological deficit. Strokes can be thrombotic or embolic in etiology and are associated with underlying conditions such as hypertension and atherosclerosis. Possible etiologies of strokes include cardioembolic disease, hematologic disorders, connective tissue disorders, and substance abuse or can be cryptogenic. Most stroke cases are seen in patients over 65 years of age...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28290933/leveraging-the-partnership-for-patients-initiative-to-improve-patient-safety-and-quality-within-the-military-health-system
#17
Heidi B King, Kimberly Kesling, Carmen Birk, Theodore Walker, Heather Taylor, Michael Datena, Brittany Burgess, Lyndsay Bower
INTRODUCTION: Partnership for Patients (PfP) was a national initiative sponsored by the Department of Health and Human Services, Centers for Medicare and Medicaid Services, to reduce preventable hospital acquired conditions (HACs) by 40% and readmissions (within 30 days) by 20%, by the end of 2013 (as compared to the baseline of CY2010). Along with partners across the nation, the Assistant Secretary of Defense for Health Affairs, Dr. Jonathan Woodson, pledged to support PfP in June 2011...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28222093/active-zone-proteins-are-transported-via-distinct-mechanisms-regulated-by-par-1-kinase
#18
Kara R Barber, Julia Tanquary, Keegan Bush, Amanda Shaw, Michael Woodson, Michael Sherman, Yogesh P Wairkar
Disruption of synapses underlies a plethora of neurodevelopmental and neurodegenerative disease. Presynaptic specialization called the active zone plays a critical role in the communication with postsynaptic neuron. While the role of many proteins at the active zones in synaptic communication is relatively well studied, very little is known about how these proteins are transported to the synapses. For example, are there distinct mechanisms for the transport of active zone components or are they all transported in the same transport vesicle? Is active zone protein transport regulated? In this report we show that overexpression of Par-1/MARK kinase, a protein whose misregulation has been implicated in Autism spectrum disorders (ASDs) and neurodegenerative disorders, lead to a specific block in the transport of an active zone protein component- Bruchpilot at Drosophila neuromuscular junctions...
February 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28194999/upper-airway-stimulation-for-obstructive-sleep-apnea-patient-reported-outcomes-after-48-months-of-follow-up
#19
M Boyd Gillespie, Ryan J Soose, B Tucker Woodson, Kingman P Strohl, Joachim T Maurer, Nico de Vries, David L Steward, Jonathan Z Baskin, M Safwan Badr, Ho-Sheng Lin, Tapan A Padhya, Sam Mickelson, W McDowell Anderson, Olivier M Vanderveken, Patrick J Strollo
Objective To assess patient-based outcomes of participants in a large cohort study-the STAR trial (Stimulation Therapy for Apnea Reduction)-48 months after implantation with an upper airway stimulation system for moderate to severe obstructive sleep apnea. Study Design A multicenter prospective cohort study. Setting Industry-supported multicenter academic and clinical setting. Subjects Participants (n = 91) at 48 months from a cohort of 126 implanted participants. Methods A total of 126 participants received an implanted upper airway stimulation system in a prospective phase III trial...
April 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28194707/obituary-a-remembrance-of-francis-m-howard-md-1922-2016
#20
Marlene Woodson-Howard
No abstract text is available yet for this article.
May 2017: Clinical Orthopaedics and related Research
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