keyword
MENU ▼
Read by QxMD icon Read
search

Culturally effective

keyword
https://www.readbyqxmd.com/read/29908449/embracing-diversity-and-transcultural-society-through-community-health-practicum-among-college-nursing-students
#1
Luna Chang, Shu-Chuan Chen, Shu-Ling Hung
Based on 2015 annual report of foreign spouse populations were above 507,266 people in Taiwan. Most of them (68%) came from Mainland China, 29% from south-east Asia. 92% of foreign spouses were female (2015). Therefore, a challenge arises for nursing students to provide care to clients with multiple cultural variations in Taiwan. The study objectives were to explore the related factors of cultural care competence and estimate the effects of a short-term reinforced cultural course. The study used a quasi-experimental design...
May 19, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29908408/the-interplay-between-light-plant-growth-regulators-and-elicitors-on-growth-and-secondary-metabolism-in-cell-cultures-of-fagonia-indica
#2
Tariq Khan, Bilal Haider Abbasi, Mubarak Ali Khan
Manipulation in the light regimes combined with the effects of plant growth regulators (PGRs) and elicitors through plant cell culture technology is a promising strategy for enhancing the yield of medicinally important secondary metabolites. In this study, the effects of interplay between PGRs, elicitors and light regimes on cell cultures of F. indica have been investigated. The results showed that callus cultures resulted in maximum biomass formation (13.2 g/L) when incubated on solid MS (Murashige and Skoog) medium containing 1...
June 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29908281/ltbp2-knockdown-and-oxidative-stress-affect-glaucoma-features-including-tgf%C3%AE-pathways-ecm-genes-expression-and-apoptosis-in-trabecular-meshwork-cells
#3
Fatemeh Suri, Shahin Yazdani, Elahe Elahi
Glaucoma is the leading cause of irreversible blindness worldwide. Although the etiology of glaucoma is incompletely understood, it is known that the extracellular matrix (ECM) of the trabecular meshwork, oxidative stress, TGFβ signaling pathways, and apoptosis are important components of glaucoma pathogenesis. These components appear to be interrelated, but knowledge on their interactions remains incomplete. Relevant to this gap in knowledge, LTBP2, glaucoma causing gene, may also be related to the mentioned components of glaucoma pathogenesis because of its putative roles in TGFβ signaling and ECM functions...
June 13, 2018: Gene
https://www.readbyqxmd.com/read/29908269/the-effect-of-zataria-multiflora-boiss-essential-oil-on-the-growth-and-citrinin-production-of-penicillium-citrinum-in-culture-media-and-cheese
#4
Fateme Akrami Mohajeri, Ali Misaghi, Hamidreza Gheisari, Afshin Akhondzadeh Basti, Assieh Amiri, Sayyed Razi Ghalebi, Zahra Derakhshan, Roohollah Dehghani Tafti
The effect of Zataria multiflora Boiss Essential oil (EO) on the growth, spore production, and citrinin production of Penicellium citrinum PTCC 5304 in the culture media as well as Iranian ultra-filtered white cheese in brine was investigated. Radial growth and spore production on the potato dextrose agar (PDA) were effectively inhibited by EO in a dose-dependent manner. At 200 ppm, the radial growth and sporulation declined by 92% and 100%, respectively. The growth was completely prevented at 400 ppm of EO on PDA and the minimum fungicidal concentration (MFC) of the oil was estimated at 400 ppm...
June 13, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29908228/identification-of-an-early-stage-biofilm-inhibitor-from-veillonella-tobetsuensis
#5
Izumi Mashima, Hiroshi Miyakawa, Frank A Scannapieco, Futoshi Nakazawa
Oral biofilm, the cause of dental caries and periodontal diseases, consists of multiple bacterial species. Streptococcus spp. and Veillonella spp. have been reported as to be initial and early colonizers of oral biofilms. Our previous studies showed that Veillonella tobetsuensis may play an important role on the development of S. gordonii biofilms without coaggregation involving extracellular biomolecules. In this study, the effect of a cyclic dipeptide autoinducer from culture supernatants from V. tobetsuensis at late-exponential growth phase on S...
June 13, 2018: Anaerobe
https://www.readbyqxmd.com/read/29908000/serpin-a1-and-the-modulation-of-type-i-collagen-turnover-effect-of-the-c-terminal-peptide-409-418-sa1-iii-in-human-dermal-fibroblasts
#6
Caterina Cipriani, Simona Pascarella, Fosca Errante, Beatrice Menicacci, Lucia Magnelli, Alessandra Mocali, Paolo Rovero, Lisa Giovannelli
The pharmacological modulation of collagen turnover is a strategy potentially useful in different skin conditions. The serine protease inhibitor Serpin A1 and portions of its C-terminal region have been investigated as collagen modulators. To clarify the mechanisms by which the C-terminal 409-418 peptide SA1-III increases extracellular type I collagen levels, to compare its activities range with that of the originator molecule Serpin A1, and to evaluate its efficacy in primary cultures from adult and aged human subjects...
June 16, 2018: Cell Biology International
https://www.readbyqxmd.com/read/29907991/lipopolysaccharide-induced-the-proliferation-of-mouse-lung-fibroblasts-by-suppressing-foxo3a-p27-pathway
#7
Nannan Gu, Shunpeng Xing, Sihan Chen, Yuxi Zhou, Tao Jiang, Yingfu Jiao, Yuan Gao, Weifeng Yu, Zhengyu He, Daxiang Wen
Aberrant aggregation and activation of lung fibroblasts is a key process in pulmonary fibrosis, but the underlying mechanism remains enigmatic. Forkhead Box O3a (FoxO3a) is considered to be an important transcription factor that could regulate both cell cycle and cell viability. To investigate the role of FoxO3a on LPS-induced lung fibroblast proliferation, we transfected FoxO3a-SiRNA or FoxO3a-OE lentivirus into cultured mouse lung fibroblasts to knockdown or overexpress FoxO3a and pretreated mouse lung fibroblasts with gefitinib to enhance FoxO3a activity...
June 16, 2018: Cell Biology International
https://www.readbyqxmd.com/read/29907831/strontium-ranelate-promotes-odonto-osteogenic-differentiation-mineralization-of-dental-papillae-cells-in-vitro-and-mineralized-tissue-formation-of-the-dental-pulp-in-vivo
#8
Alamuddin Bakhit, Nobuyuki Kawashima, Kentaro Hashimoto, Sonoko Noda, Keisuke Nara, Masashi Kuramoto, Kento Tazawa, Takashi Okiji
This study examined the effects and mechanisms of strontium ranelate (SrRn)-a drug used to treat osteoporosis-on the proliferation and differentiation/mineralization of cloned dental pulp-like cells (mouse dental papillae cells; MDPs). It also determined whether topical application of SrRn to exposed dental pulp tissue promotes the formation of mineralized tissue in vivo. The MDPs were cultured with or without SrRn, and cell proliferation, odonto-/osteoblastic gene expression, mineralized nodule formation, and Akt phosphorylation were evaluated...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907830/substance-p-modulates-bone-remodeling-properties-of-murine-osteoblasts-and-osteoclasts
#9
Tanja Niedermair, Stephan Schirner, Raphael Seebröker, Rainer H Straub, Susanne Grässel
Clinical observations suggest neuronal control of bone remodeling. Sensory nerve fibers innervating bone, bone marrow and periosteum signal via neurotransmitters including substance P (SP). In previous studies we observed impaired biomechanical and structural bone parameters in tachykinin (Tac) 1-deficient mice lacking SP. Here, we aim to specify effects of SP on metabolic parameters of bone marrow macrophage (BMM)/osteoclast cultures and osteoblasts isolated from Tac1-deficient and wildtype (WT) mice. We demonstrated endogenous SP production and secretion in WT bone cells...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907804/administration-of-molecular-hydrogen-during-pregnancy-improves-behavioral-abnormalities-of-offspring-in-a-maternal-immune-activation-model
#10
Kenji Imai, Tomomi Kotani, Hiroyuki Tsuda, Tomoko Nakano, Takafumi Ushida, Akira Iwase, Taku Nagai, Shinya Toyokuni, Akio Suzumura, Fumitaka Kikkawa
The aim of the present study was to investigate long-term outcomes of the offspring in a lipopolysaccharide (LPS)-induced maternal immune activation (MIA) model and the effect of maternal molecular hydrogen (H2 ) administration. We have previously demonstrated in the MIA mouse model that maternal administration of H2 attenuates oxidative damage and neuroinflammation, including induced pro-inflammatory cytokines and microglial activation, in the fetal brain. Short-term memory, sociability and social novelty, and sensorimotor gating were evaluated using the Y-maze, three-chamber, and prepulse inhibition (PPI) tests, respectively, at postnatal 3 or 4 weeks...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907803/effect-of-temperature-on-burkholderia-pseudomallei-growth-proteomic-changes-motility-and-resistance-to-stress-environments
#11
Suporn Paksanont, Kitisak Sintiprungrat, Thatcha Yimthin, Pornpan Pumirat, Sharon J Peacock, Narisara Chantratita
Burkholderia pseudomallei is a flagellated, gram-negative environmental bacterium that causes melioidosis, a severe infectious disease of humans and animals in tropical areas. We hypothesised that B. pseudomallei may undergo phenotypic adaptation in response to an increase in growth temperature. We analysed the growth curves of B. pseudomallei strain 153 cultured in Luria-Bertani broth at five different temperatures (25 °C-42 °C) and compared the proteomes of bacteria cultured at 37 °C and 42 °C...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907556/veterans-perspectives-on-fitbit-use-in-treatment-for-post-traumatic-stress-disorder-an-interview-study
#12
Ada Ng, Madhu Reddy, Alyson K Zalta, Stephen M Schueller
BACKGROUND: The increase in availability of patient data through consumer health wearable devices and mobile phone sensors provides opportunities for mental health treatment beyond traditional self-report measurements. Previous studies have suggested that wearables can be effectively used to benefit the physical health of people with mental health issues, but little research has explored the integration of wearable devices into mental health care. As such, early research is still necessary to address factors that might impact integration including patients' motivations to use wearables and their subsequent data...
June 15, 2018: JMIR Mental Health
https://www.readbyqxmd.com/read/29907529/kinetic-analysis-on-precursors-for-iturin-a-production-from-bacillus-amyloliquefaciens-bpd1
#13
Jiun-Yan Wu, Jen-Hung Liao, Chwen-Jen Shieh, Feng-Chia Hsieh, Yung-Chuan Liu
In this study, the precursor effect for iturin A production was quantitatively analyzed. A strain identified as Bacillus amyloliquefaciens BPD1 (Ba-BPD1) was selected due to its ability to produce iturin A. The enhancement of iturin A production in a submerged culture was tested using various additives, including palmitic acid, oils, and complex amino acids. Among these, complex amino acids triggered the highest yield at 559 mg/L. The respective amino acids that contribute to the structure of iturin A were used as precursors...
June 12, 2018: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/29907377/neurotropin-inhibits-neuronal-activity-through-potentiation-of-sustained-k-v-currents-in-primary-cultured-drg-neurons
#14
Hiroyuki Kawai, Nozomi Asaoka, Takahito Miyake, Kazuki Nagayasu, Takayuki Nakagawa, Hisashi Shirakawa, Shuji Kaneko
Neurotropin (NTP) is a Japanese analgesic agent for treating neuropathic pain; however, its method of action remains unclear. This study examined the effects of NTP on the activity of small dorsal root ganglion (DRG) neurons using whole-cell patch clamp recordings. After 3 days of treatment, NTP decreased current injection-induced firing activity of cultured DRG neurons by raising the current threshold for action potential generation. Additionally, NTP increased the sustained component of voltage-gated potassium (Kv ) channel currents without affecting other K+ currents...
May 31, 2018: Journal of Pharmacological Sciences
https://www.readbyqxmd.com/read/29907324/nonlinear-effects-of-caffeine-on-the-viability-synthesis-and-gene-expression-of-chondrocytes-from-the-offspring-of-rats-treated-during-pregnancy
#15
Amanda Maria Sena Reis, Karina Pessoa Oliveira, Isabela Helena Fagundes de Paula, Alisson Paulo da Silva, Júlia Fahrion Tarragô, Natália de Melo Ocarino, Rogéria Serakides
OBJECTIVE: Evaluate the effects of doses of caffeine administered to pregnant rats on the articular cartilage chondrocytes of their offspring. METHODS: Twenty-four adult Wistar rats were randomly assigned to four groups, with one control group and three groups being treated with caffeine at doses of 25, 50 and 100 mg/kg throughout pregnancy. At birth, three offspring/females were euthanized so that the chondrocytes could be extracted. At 7, 14 and 21 days of culture, the chondrocytes were subjected to the MTT cell viability assay and an evaluation of their alkaline phosphatase activity and collagen synthesis...
June 12, 2018: Acta Histochemica
https://www.readbyqxmd.com/read/29907294/new-colorimetric-aptasensor-for-rapid-on-site-detection-of-campylobacter-jejuni-and-campylobacter-coli-in-chicken-carcass-samples
#16
Young-Ji Kim, Hong-Seok Kim, Jung-Whan Chon, Dong-Hyeon Kim, Ji-Yeon Hyeon, Kun-Ho Seo
Campylobacter is the most common cause of infectious intestinal disease, with nearly all cases caused by two species: C. jejuni and C. coli. We recently reported a gold nanoparticle-based two-stage aptasensing platform, which was improved in the present study for the rapid and on-site detection of both C. jejuni and C. coli in food samples. Compared to the previous platform, the improved platform yielded a more obvious colour change from red to purple due to the aggregation of gold nanoparticles, and does not require additional time or a pH optimization step for the aptamers to be adsorbed onto the gold nanoparticles...
October 31, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29907223/an-evidence-based-intraoperative-communication-tool-for-emergency-general-surgery-a-pilot-study
#17
Alexandra B Columbus, Manuel Castillo-Angeles, William R Berry, Adil H Haider, Ali Salim, Joaquim M Havens
BACKGROUND: Emergency general surgery (EGS) is characterized by high rates of morbidity and mortality. Though checklists and associated communication-based huddle strategies have improved outcomes, these tools have never been specifically examined in EGS. We hypothesized that use of an evidence-based communication tool aimed to trigger intraoperative discussion could improve communication in the EGS operating room (OR). MATERIALS AND METHODS: We designed a set of discussion prompts based on modifiable factors identified from previously published studies aimed to encourage all team members to speak up and to centralize awareness of patient disposition and intraoperative transfusion practices...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29907098/ip-3-r-grp75-vdac1-mcu-calcium-regulation-axis-antagonists-protect-podocytes-from-apoptosis-and-decrease-proteinuria-in-an-adriamycin-nephropathy-rat-model
#18
Han Xu, Na Guan, Ya-Li Ren, Qi-Jiao Wei, Ying-Hong Tao, Guo-Sheng Yang, Xiao-Ya Liu, Ding-Fang Bu, Ying Zhang, Sai-Nan Zhu
BACKGROUND: The mechanism of podocyte apoptosis is not fully understood. In addition, the role of the inositol 1,4,5-triphosphate receptor (IP3 R)/glucose-regulated protein 75 (Grp75)/voltage-dependent anion channel 1 (VDAC1)/mitochondrial calcium uniporter (MCU) calcium regulation axis, which is located at sites of endoplasmic reticulum (ER) mitochondria coupling, in the mechanism of podocyte apoptosis is unclear. This study aimed to understand the roles of this axis in podocyte apoptosis and explore potential targets for podocyte protection...
June 15, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29907093/effect-of-administration-of-a-probiotic-preparation-on-gut-microbiota-and-immune-response-in-healthy-women-in-india-an-open-label-single-arm-pilot-study
#19
Ankita Singh, Aditya N Sarangi, Amit Goel, Rajni Srivastava, Rajat Bhargava, Priyanka Gaur, Amita Aggarwal, Rakesh Aggarwal
BACKGROUND: Probiotics have been shown to be useful for the treatment of many disease conditions. These beneficial effects are believed to be mediated by change in the composition of gut microbiota and modulation of the host immune responses. However, the available data on the effect of probiotics on these parameters are quite limited. METHODS: We studied the composition of fecal microbiota, using 16S rRNA sequencing, and host immune responses in peripheral blood (plasma cytokine levels, T cell subsets and in vitro cytokine production after stimulation with anti-CD3/CD28 antibody or lipopolysaccharide) in a group of 14 healthy women at three time-points - before and after administration of a probiotic preparation (a capsule of VSL#3, each containing 112...
June 15, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29906703/modulation-of-serum-albumin-protein-corona-for-exploring-cellular-behaviors-of-fattigation-platform-nanoparticles
#20
Van Hong Nguyen, Nilesh M Meghani, Hardik H Amin, Thao T D Tran, Phuong H L Tran, Chulhun Park, Beom-Jin Lee
Albumin is the most abundant protein in blood, and is the most frequently identified protein in the protein corona of nanoparticles (NPs). Thus, albumin plays an important role in modulating NPs' physicochemical properties and bioavailability. In this study, the effect of bovine serum albumin (BSA) on gelatin-oleic nanoparticles' (GONs) physicochemical properties and cellular uptake were evaluated. Coumarin-6 was used as indicator to track the cellular uptake of GONs. The binding of BSA onto the GON surface increased the size, slightly reduced the negative net charge of the GON, and improved GON stability...
May 28, 2018: Colloids and Surfaces. B, Biointerfaces
keyword
keyword
1495
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"