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https://www.readbyqxmd.com/read/28683406/crimes-against-the-elderly-in-italy-2007-2014
#1
Claudio Terranova, Greta Bevilacqua, Margherita Zen, Massimo Montisci
Crimes against the elderly have physical, psychological, and economic consequences. Approaches for mitigating them must be based on comprehensive knowledge of the phenomenon. This study analyses crimes against the elderly in Italy during the period 2007-2014 from an epidemiological viewpoint. Data on violent and non-violent crimes derived from the Italian Institute of Statistics were analysed in relation to trends, gender and age by linear regression, T-test, and calculation of the odds ratio with a 95% confidence interval...
June 27, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28646652/influenza-a-virus-cap-snatches-host-rnas-based-on-their-abundance-early-after-infection
#2
Dorota Sikora, Lynda Rocheleau, Earl G Brown, Martin Pelchat
The influenza A virus RNA polymerase cleaves the 5' ends of host RNAs and uses these RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5' host-derived ends of the eight viral mRNAs of influenza A/Puerto Rico/8/1934 (H1N1) virus in infected A549 cells, and compared the population to those of A/Hong Kong/1/1968 (H3N2) and A/WSN/1933 (H1N1). In the three strains, the viral RNAs target different populations of host RNAs. Host RNAs are cap-snatched based on their abundance, and we found that RNAs encoding proteins involved in metabolism are overrepresented in the cap-snatched populations...
June 21, 2017: Virology
https://www.readbyqxmd.com/read/28566349/lateralisation-helps-sailfish-snatch-sardines
#3
C Ruth Archer
No abstract text is available yet for this article.
June 1, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28538310/enhancing-digital-video-analysis-of-bar-kinematics-in-weightlifting-a-case-study
#4
Torstein E Dæhlin, Tron Krosshaug, Loren Z F Chiu
Dæhlin, TE, Krosshaug, T, and Chiu, LZF. Enhancing digital video analysis of bar kinematics in weightlifting: a case study. J Strength Cond Res 31(6): 1592-1600, 2017-Weightlifting technique can be objectively assessed from two-dimensional video recordings. Despite its importance, participants' bar trajectories in research involving the snatch or clean exercises are often not reported, potentially due to the time required to digitize video. The purpose of this investigation was to evaluate the use of a light-emitting diode (LED)-based marker, digital video, and open-source software to automatically track the bar end during weightlifting exercises...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28538307/can-cold-water-immersion-enhance-recovery-in-elite-olympic-weightlifters-an-individualized-perspective
#5
Jan Schimpchen, Maximilian Wagner, Alexander Ferrauti, Michael Kellmann, Mark Pfeiffer, Tim Meyer
We investigated whether cold water immersion (CWI) after intensive training sessions can enhance recovery in elite Olympic weightlifters, taking into account each athlete's individual response pattern. The entire German male Olympic weightlifting national team participated in the study (n = 7), ensuring collection of data from elite athletes only. Using a randomized cross-over design, the athletes went through 2 high-intensity training microcycles consisting of 5 training sessions that were either followed by a CWI or passive recovery...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28527860/biochemical-principles-and-inhibitors-to-interfere-with-viral-capping-pathways
#6
REVIEW
Etienne Decroly, Bruno Canard
Messenger RNAs are decorated by a cap structure, which is essential for their translation into proteins. Many viruses have developed strategies in order to cap their mRNAs. The cap is either synthetized by a subset of viral or cellular enzymes, or stolen from capped cellular mRNAs by viral endonucleases ('cap-snatching'). Reverse genetic studies provide evidence that inhibition of viral enzymes belonging to the capping pathway leads to inhibition of virus replication. The replication defect results from reduced protein synthesis as well as from detection of incompletely capped RNAs by cellular innate immunity sensors...
May 18, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28505175/structural-insights-into-reptarenavirus-cap-snatching-machinery
#7
Maria Rosenthal, Nadja Gogrefe, Dominik Vogel, Juan Reguera, Bianka Rauschenberger, Stephen Cusack, Stephan Günther, Sophia Reindl
Cap-snatching was first discovered in influenza virus. Structures of the involved domains of the influenza virus polymerase, namely the endonuclease in the PA subunit and the cap-binding domain in the PB2 subunit, have been solved. Cap-snatching endonucleases have also been demonstrated at the very N-terminus of the L proteins of mammarena-, orthobunya-, and hantaviruses. However, a cap-binding domain has not been identified in an arena- or bunyavirus L protein so far. We solved the structure of the 326 C-terminal residues of the L protein of California Academy of Sciences virus (CASV), a reptarenavirus, by X-ray crystallography...
May 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28418734/bunyaviridae-rdrps-structure-motifs-and-rna-synthesis-machinery
#8
Abdennour Amroun, Stéphane Priet, Xavier de Lamballerie, Gilles Quérat
Bunyaviridae family is the largest and most diverse family of RNA viruses. It has more than 350 members divided into five genera: Orthobunyavirus, Phlebovirus, Nairovirus, Hantavirus, and Tospovirus. They are present in the five continents, causing recurrent epidemics, epizootics, and considerable agricultural loss. The genome of bunyaviruses is divided into three segments of negative single-stranded RNA according to their relative size: L (Large), M (Medium) and S (Small) segment. Bunyaviridae RNA-dependent RNA polymerase (RdRp) is encoded by the L segment, and is in charge of the replication and transcription of the viral RNA in the cytoplasm of the infected cell...
April 18, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28394829/electromyographical-comparison-of-muscle-activation-patterns-across-three-commonly-performed-kettlebell-exercises
#9
Brian C Lyons, Jerry J Mayo, W Steve Tucker, Ben Wax, Russell C Hendrix
The purpose of this study was to compare the muscle activation patterns of three different kettlebell (KB) exercises using electromyography (EMG). Fourteen resistance-trained subjects completed a one-arm swing (Swing), one-arm swing style snatch (Snatch), and a one-arm clean (Clean) using a self-selected 8-10 RM load for each exercise. Trial sessions consisted of subjects performing 5 repetitions of each kettlebell exercise. Mean EMG was used to assess the muscle activation of the biceps brachii (BB), anterior deltoid (AD), posterior deltoid (PD), erector spinae (ES), vastus lateralis (VL), biceps femoris (BF), contralateral external oblique (EO), and gluteus maximus (GM) during each lift using surface electrodes...
December 20, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28367368/external-kinetics-of-the-kettlebell-snatch-in-amateur-lifters
#10
James A Ross, Justin W L Keogh, Cameron J Wilson, Christian Lorenzen
BACKGROUND: Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch continuously over prolonged periods of time. Kettlebell sport and weightlifting involve similar exercises, however, their traditional uses suggest they are better suited to training different fitness qualities. This study examined the three-dimensional ground reaction force (GRF) and force applied to the kettlebell over a 6 min kettlebell snatch set in 12 kettlebell-trained males...
2017: PeerJ
https://www.readbyqxmd.com/read/28224857/women-of-the-world-are-saying-this-is-wrong
#11
Genevieve Edwards
As part of the Marie Stopes UK team, I believe that every woman has the right to choose whether and when to have children. But for millions of women worldwide, that right has just been snatched away.
February 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28195976/self-reported-measures-of-strength-and-sport-specific-skills-distinguish-ranking-in-an-international-online-fitness-competition
#12
Paul R Serafini, Yuri Feito, Gerald T Mangine
To determine if self-reported performance measures could distinguish ranking during the 2016 CrossFit Open, data from three thousand male (n=1500; 27.2±8.4 y; 85.2±7.9 kg; 177.0±6.5 cm) and female (n=1500, 28.7±4.9 y; 63.7±5.8 kg; 163.7±6.6 cm) competitors was used for this study. Competitors were split by gender and grouped into quintiles (Q1-Q5) based upon their final ranking. Quintiles were compared for one-repetition maximum (1RM) squat, deadlift, clean and jerk (CJ), snatch, 400-m sprint, 5,000-m run, and benchmark workouts (Fran, Helen, Grace, Filthy-50, and Fight-gone-bad)...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28195975/the-high-bar-and-low-bar-back-squats-a-biomechanical-analysis
#13
Daniel J Glassbrook, Scott R Brown, Eric R Helms, J Scott Duncan, Adam G Storey
No prior study has compared the joint angle and ground reaction force (Fv) differences between the high-bar back-squat (HBBS) and low-bar back-squat (LBBS) above 90% 1RM. Six male powerlifters (height: 179.2 ± 7.8 cm; bodyweight: 87.1 ± 8.0 kg; age: 27.3 ± 4.2 years) of international level, six male Olympic weightlifters (height: 176.7 ± 7.7 cm; bodyweight: 83.1 ± 13 kg; age: 25.3 ± 3.1 years) of national level, and six recreationally trained male athletes (height: 181.9 ± 8.7 cm; bodyweight: 87.9 ± 15...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28154333/structural-and-biochemical-analyses-on-the-rna-dependent-rna-polymerase-of-influenza-virus-for-development-of-novel-anti-influenza-agents
#14
REVIEW
Dai Hatakeyama
 The PA, PB1, and PB2 subunits, components of the RNA-dependent RNA polymerase of influenza A virus, and the nucleoprotein (NP) interact with the genomic RNA of influenza viruses and form ribonucleoproteins. Especially, the PB2 subunit binds to the host RNA cap [7-methylguanosine triphosphate (m(7)GTP)] and supports the endonuclease activity of PA to "snatch" the cap from host pre-mRNAs. In this study, we describe a novel Val/Arg/Gly (VRG) site in the PB2 cap-binding domain, which is necessary for interaction with acetyl-CoA found in eukaryotic histone acetyltransferases (HATs)...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28122973/role-of-the-pb2-627-domain-in-influenza-a-virus-polymerase-function
#15
Benjamin E Nilsson, Aartjan J W Te Velthuis, Ervin Fodor
The RNA genome of influenza A viruses is transcribed and replicated by the viral RNA-dependent RNA polymerase, composed of the subunits PA, PB1, and PB2. High-resolution structural data revealed that the polymerase assembles into a central polymerase core and several auxiliary highly flexible, protruding domains. The auxiliary PB2 cap-binding and the PA endonuclease domains are both involved in cap snatching, but the role of the auxiliary PB2 627 domain, implicated in host range restriction of influenza A viruses, is still poorly understood...
April 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28115197/structural-insights-into-rna-synthesis-by-the-influenza-virus-transcription-replication-machine
#16
REVIEW
Alexander Pflug, Maria Lukarska, Patricia Resa-Infante, Stefan Reich, Stephen Cusack
Influenza virus is a segmented, negative strand RNA virus with each genome segment being packaged in a distinct ribonucleoprotein particle (RNP). The RNP consists of the heterotrimeric viral RNA-dependent RNA polymerase bound to the conserved 5' and 3' ends of the genome segment (the viral promoter) with the rest of the viral RNA (vRNA) being covered by multiple copies of nucleoprotein. This review focusses on the new insights that recent crystal structures have given into the detailed molecular mechanisms by which the polymerase performs both transcription and replication of the vRNA genome...
January 20, 2017: Virus Research
https://www.readbyqxmd.com/read/28112978/calling-texting-and-searching-for-information-while-riding-a-motorcycle-a-study-of-university-students-in-vietnam
#17
Long T Truong, Chris De Gruyter, Hang T T Nguyen
OBJECTIVE: The objective of this study was to investigate the prevalence of calling, texting, and searching for information while riding a motorcycle among university students and the influences of sociodemographic characteristics, social norms, and risk perceptions on these behaviors. METHODS: Students at 2 university campuses in Hanoi and Ho Chi Minh City, the 2 largest cities in Vietnam, were invited to participate in an anonymous online survey. Data collection was conducted during March and May 2016...
August 18, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28030531/does-focus-of-attention-improve-snatch-lift-kinematics
#18
Kyle S Schutts, Will Wu, Anthony Vidal, Jamie Hiegel, James Becker
Recent motor control literature has demonstrated that using verbal instructions to direct a performer's attention externally (i.e. toward the movement outcome) enhances motor skill performance. The purpose of this study was to investigate how an athlete's focus of attention impacts kinematic performance of the snatch. Using a counterbalanced within-participant design, 12 competitively trained athletes (8 male, 4 female) performed 2 instructional blocks of 3 snatch repetitions at 80% of their most recent training 1RM...
December 24, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27994826/crossfit-%C3%A2-instructor-demographics-and-practice-trends
#19
Gregory R Waryasz, Vladimir Suric, Alan H Daniels, Joseph A Gil, Craig P Eberson
CrossFit(®) is an increasingly popular exercise modality that uses high intensity power training. The literature to date regarding CrossFit(®) has focused on its benefits to VO2 Max, body composition and the motivational variables of participants of CrossFit(®). A computerized survey was distributed to CrossFit(®) instructors using Survey Monkey(®) (Palo Alto, CA, USA). One hundred and ninety-three CrossFit(®) instructors responded to the survey. Of these 86.6% (155/179) reported being a certified CrossFit(®) instructor with 26...
November 17, 2016: Orthopedic Reviews
https://www.readbyqxmd.com/read/27820725/training-strategies-to-improve-muscle-power-is-olympic-style-weightlifting-relevant
#20
Christian Helland, Eirik Hole, Erik Iversen, Monica Charlotte Olsson, Olivier Seynnes, Paul Andre Solberg, Gøran Paulsen
INTRODUCTION: This efficacy study investigated the effects of 1) Olympic-style weightlifting (OWL), 2) motorized strength and power training (MSPT), and 3) free weight strength and power training (FSPT) on muscle power. METHODS: Thirty-nine young athletes (20 ± 3 yr; ice hockey, volleyball, and badminton) were randomized into the three training groups. All groups participated in two to three sessions per week for 8 wk. The MSPT and FSPT groups trained using squats (two legs and single leg) with high force and high power, whereas the OWL group trained using clean and snatch exercises...
April 2017: Medicine and Science in Sports and Exercise
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