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https://www.readbyqxmd.com/read/28933236/evaluating-the-contribution-of-lower-extremity-kinetics-to-whole-body-power-output-during-the-power-snatch
#1
Sangwoo Lee, Kyle D DeRosia, Landon M Lamie
This study evaluated the contribution of lower extremity (hip, knee and ankle) net joint torques (NJT) to whole body power (WBP) output during the power snatch (PS). Ten experienced weightlifters (five males and five females) performed five trials of the PS with 60% of one repetition maximum. Lower extremity NJT and WBP were extracted through a three-dimensional motion analyses and used for data analyses. Pearson correlation coefficients were obtained to observe the relationship between lower extremity NJT and WBP...
September 21, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28928453/molecular-characterization-of-emaraviruses-associated-with-pigeonpea-sterility-mosaic-disease
#2
Surender Kumar, B L Subbarao, Vipin Hallan
Sterility Mosaic Disease (SMD) of pigeonpea (Cajanus cajan (L.) Millspaugh) is a complex disease due to various factors including the presence of a mixed infection. Comparison of dsRNA profile and small RNA (sRNA) deep sequencing analysis of samples from three locations revealed the presence of Pigeonpea sterility mosaic virus-I and II (PPSMV-I and II) from Chevella and only PPSMV-II from Bengaluru and Coimbatore. PPSMV-I genome consisted of four while PPSMV-II encompassed six RNAs. The two viruses have modest sequence homology between their corresponding RNA 1-4 encoding RdRp, glycoprotein precursor, nucleocapsid and movement proteins and the corresponding orthologs of other emaraviruses...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28845095/school-aged-children-s-experiences-7-and-13-months-following-a-sibling-s-death
#3
Dorothy Brooten, JoAnne M Youngblut
This study described 6-year to 12-year-old children's responses 7 and 13 months after siblings' NICU/PICU/ED death. Using semi-structured interviews, at 7 months, children were asked about events around their sibling's death. At both 7 and 13 months, children were asked about their thoughts and feelings about the deceased, concerns or fears, and life changes since the death. Thirty one children (58% female), recruited from four South Florida hospitals and Florida obituaries, participated. Children's mean age was 8...
April 2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/28839261/structural-basis-for-therapeutic-inhibition-of-influenza-a-polymerase-pb2-subunit
#4
Xiaolei Ma, Lili Xie, Charles Wartchow, Robert Warne, Yongjin Xu, Alexey Rivkin, David Tully, Steven Shia, Kyoko Uehara, Dianna M Baldwin, Gladys Muiru, Weidong Zhong, Isabel Zaror, Dirksen E Bussiere, Vincent H J Leonard
Influenza virus uses a unique mechanism to initiate viral transcription named cap-snatching. The PB2 subunit of the viral heterotrimeric RNA polymerase binds the cap structure of cellular pre-mRNA to promote its cleavage by the PA subunit. The resulting 11-13 capped oligomer is used by the PB1 polymerase subunit to initiate transcription of viral proteins. VX-787 is an inhibitor of the influenza A virus pre-mRNA cap-binding protein PB2. This clinical stage compound was shown to bind the minimal cap-binding domain of PB2 to inhibit the cap-snatching machinery...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28812510/make-jeremy-hunt-read-ns
#5
Penny Mannings
Jeremy Hunt should be put in a darkened room with a supply of Nursing Standard and - over a 12-hour shift with a snatched toilet break/cup of coffee - forced to read from cover to cover.
August 16, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28683406/crimes-against-the-elderly-in-italy-2007-2014
#6
Claudio Terranova, Greta Bevilacqua, Margherita Zen, Massimo Montisci
Crimes against the elderly have physical, psychological, and economic consequences. Approaches for mitigating them must be based on comprehensive knowledge of the phenomenon. This study analyses crimes against the elderly in Italy during the period 2007-2014 from an epidemiological viewpoint. Data on violent and non-violent crimes derived from the Italian Institute of Statistics were analysed in relation to trends, gender and age by linear regression, T-test, and calculation of the odds ratio with a 95% confidence interval...
June 27, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28646652/influenza-a-virus-cap-snatches-host-rnas-based-on-their-abundance-early-after-infection
#7
Dorota Sikora, Lynda Rocheleau, Earl G Brown, Martin Pelchat
The influenza A virus RNA polymerase cleaves the 5' ends of host RNAs and uses these RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5' host-derived ends of the eight viral mRNAs of influenza A/Puerto Rico/8/1934 (H1N1) virus in infected A549 cells, and compared the population to those of A/Hong Kong/1/1968 (H3N2) and A/WSN/1933 (H1N1). In the three strains, the viral RNAs target different populations of host RNAs. Host RNAs are cap-snatched based on their abundance, and we found that RNAs encoding proteins involved in metabolism are overrepresented in the cap-snatched populations...
September 2017: Virology
https://www.readbyqxmd.com/read/28566349/lateralisation-helps-sailfish-snatch-sardines
#8
C Ruth Archer
No abstract text is available yet for this article.
June 1, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28538310/enhancing-digital-video-analysis-of-bar-kinematics-in-weightlifting-a-case-study
#9
Torstein E Dæhlin, Tron Krosshaug, Loren Z F Chiu
Dæhlin, TE, Krosshaug, T, and Chiu, LZF. Enhancing digital video analysis of bar kinematics in weightlifting: a case study. J Strength Cond Res 31(6): 1592-1600, 2017-Weightlifting technique can be objectively assessed from two-dimensional video recordings. Despite its importance, participants' bar trajectories in research involving the snatch or clean exercises are often not reported, potentially due to the time required to digitize video. The purpose of this investigation was to evaluate the use of a light-emitting diode (LED)-based marker, digital video, and open-source software to automatically track the bar end during weightlifting exercises...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28538307/can-cold-water-immersion-enhance-recovery-in-elite-olympic-weightlifters-an-individualized-perspective
#10
Jan Schimpchen, Maximilian Wagner, Alexander Ferrauti, Michael Kellmann, Mark Pfeiffer, Tim Meyer
We investigated whether cold water immersion (CWI) after intensive training sessions can enhance recovery in elite Olympic weightlifters, taking into account each athlete's individual response pattern. The entire German male Olympic weightlifting national team participated in the study (n = 7), ensuring collection of data from elite athletes only. Using a randomized cross-over design, the athletes went through 2 high-intensity training microcycles consisting of 5 training sessions that were either followed by a CWI or passive recovery...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28527860/biochemical-principles-and-inhibitors-to-interfere-with-viral-capping-pathways
#11
REVIEW
Etienne Decroly, Bruno Canard
Messenger RNAs are decorated by a cap structure, which is essential for their translation into proteins. Many viruses have developed strategies in order to cap their mRNAs. The cap is either synthetized by a subset of viral or cellular enzymes, or stolen from capped cellular mRNAs by viral endonucleases ('cap-snatching'). Reverse genetic studies provide evidence that inhibition of viral enzymes belonging to the capping pathway leads to inhibition of virus replication. The replication defect results from reduced protein synthesis as well as from detection of incompletely capped RNAs by cellular innate immunity sensors...
May 18, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28505175/structural-insights-into-reptarenavirus-cap-snatching-machinery
#12
Maria Rosenthal, Nadja Gogrefe, Dominik Vogel, Juan Reguera, Bianka Rauschenberger, Stephen Cusack, Stephan Günther, Sophia Reindl
Cap-snatching was first discovered in influenza virus. Structures of the involved domains of the influenza virus polymerase, namely the endonuclease in the PA subunit and the cap-binding domain in the PB2 subunit, have been solved. Cap-snatching endonucleases have also been demonstrated at the very N-terminus of the L proteins of mammarena-, orthobunya-, and hantaviruses. However, a cap-binding domain has not been identified in an arena- or bunyavirus L protein so far. We solved the structure of the 326 C-terminal residues of the L protein of California Academy of Sciences virus (CASV), a reptarenavirus, by X-ray crystallography...
May 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28418734/bunyaviridae-rdrps-structure-motifs-and-rna-synthesis-machinery
#13
Abdennour Amroun, Stéphane Priet, Xavier de Lamballerie, Gilles Quérat
Bunyaviridae family is the largest and most diverse family of RNA viruses. It has more than 350 members divided into five genera: Orthobunyavirus, Phlebovirus, Nairovirus, Hantavirus, and Tospovirus. They are present in the five continents, causing recurrent epidemics, epizootics, and considerable agricultural loss. The genome of bunyaviruses is divided into three segments of negative single-stranded RNA according to their relative size: L (Large), M (Medium) and S (Small) segment. Bunyaviridae RNA-dependent RNA polymerase (RdRp) is encoded by the L segment, and is in charge of the replication and transcription of the viral RNA in the cytoplasm of the infected cell...
April 18, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28394829/electromyographical-comparison-of-muscle-activation-patterns-across-three-commonly-performed-kettlebell-exercises
#14
Brian C Lyons, Jerry J Mayo, W Steven Tucker, Ben Wax, Russell C Hendrix
Lyons, BC, Mayo, JJ, Tucker, WS, Wax, B, and Hendrix, RC. Electromyographical comparison of muscle activation patterns across 3 commonly performed kettlebell exercises. J Strength Cond Res 31(9): 2363-2370, 2017-The purpose of this study was to compare the muscle activation patterns of 3 different kettlebell (KB) exercises using electromyography (EMG). Fourteen resistance-trained subjects completed a 1-arm swing (Swing), 1-arm swing style snatch (Snatch), and a 1-arm clean (Clean) using a self-selected 8 to 10 repetition maximum load for each exercise...
September 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28367368/external-kinetics-of-the-kettlebell-snatch-in-amateur-lifters
#15
James A Ross, Justin W L Keogh, Cameron J Wilson, Christian Lorenzen
BACKGROUND: Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch continuously over prolonged periods of time. Kettlebell sport and weightlifting involve similar exercises, however, their traditional uses suggest they are better suited to training different fitness qualities. This study examined the three-dimensional ground reaction force (GRF) and force applied to the kettlebell over a 6 min kettlebell snatch set in 12 kettlebell-trained males...
2017: PeerJ
https://www.readbyqxmd.com/read/28224857/women-of-the-world-are-saying-this-is-wrong
#16
Genevieve Edwards
As part of the Marie Stopes UK team, I believe that every woman has the right to choose whether and when to have children. But for millions of women worldwide, that right has just been snatched away.
February 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28195976/self-reported-measures-of-strength-and-sport-specific-skills-distinguish-ranking-in-an-international-online-fitness-competition
#17
Paul R Serafini, Yuri Feito, Gerald T Mangine
To determine if self-reported performance measures could distinguish ranking during the 2016 CrossFit Open, data from three thousand male (n=1500; 27.2±8.4 y; 85.2±7.9 kg; 177.0±6.5 cm) and female (n=1500, 28.7±4.9 y; 63.7±5.8 kg; 163.7±6.6 cm) competitors was used for this study. Competitors were split by gender and grouped into quintiles (Q1-Q5) based upon their final ranking. Quintiles were compared for one-repetition maximum (1RM) squat, deadlift, clean and jerk (CJ), snatch, 400-m sprint, 5,000-m run, and benchmark workouts (Fran, Helen, Grace, Filthy-50, and Fight-gone-bad)...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28195975/the-high-bar-and-low-bar-back-squats-a-biomechanical-analysis
#18
Daniel J Glassbrook, Scott R Brown, Eric R Helms, J Scott Duncan, Adam G Storey
No prior study has compared the joint angle and ground reaction force (Fv) differences between the high-bar back-squat (HBBS) and low-bar back-squat (LBBS) above 90% 1RM. Six male powerlifters (height: 179.2 ± 7.8 cm; bodyweight: 87.1 ± 8.0 kg; age: 27.3 ± 4.2 years) of international level, six male Olympic weightlifters (height: 176.7 ± 7.7 cm; bodyweight: 83.1 ± 13 kg; age: 25.3 ± 3.1 years) of national level, and six recreationally trained male athletes (height: 181.9 ± 8.7 cm; bodyweight: 87.9 ± 15...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28154333/structural-and-biochemical-analyses-on-the-rna-dependent-rna-polymerase-of-influenza-virus-for-development-of-novel-anti-influenza-agents
#19
REVIEW
Dai Hatakeyama
 The PA, PB1, and PB2 subunits, components of the RNA-dependent RNA polymerase of influenza A virus, and the nucleoprotein (NP) interact with the genomic RNA of influenza viruses and form ribonucleoproteins. Especially, the PB2 subunit binds to the host RNA cap [7-methylguanosine triphosphate (m(7)GTP)] and supports the endonuclease activity of PA to "snatch" the cap from host pre-mRNAs. In this study, we describe a novel Val/Arg/Gly (VRG) site in the PB2 cap-binding domain, which is necessary for interaction with acetyl-CoA found in eukaryotic histone acetyltransferases (HATs)...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28122973/role-of-the-pb2-627-domain-in-influenza-a-virus-polymerase-function
#20
Benjamin E Nilsson, Aartjan J W Te Velthuis, Ervin Fodor
The RNA genome of influenza A viruses is transcribed and replicated by the viral RNA-dependent RNA polymerase, composed of the subunits PA, PB1, and PB2. High-resolution structural data revealed that the polymerase assembles into a central polymerase core and several auxiliary highly flexible, protruding domains. The auxiliary PB2 cap-binding and the PA endonuclease domains are both involved in cap snatching, but the role of the auxiliary PB2 627 domain, implicated in host range restriction of influenza A viruses, is still poorly understood...
April 1, 2017: Journal of Virology
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