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https://www.readbyqxmd.com/read/28076561/visual-outcomes-after-deep-anterior-lamellar-keratoplasty-using-donor-corneas-without-removal-of-descemet-membrane-and-endothelium
#1
Tatiana Moura Bastos Prazeres, Rodrigo Muller, Tatiana Rayes, Flavio Eduardo Hirai, Luciene Barbosa de Sousa
Purpose: The optical quality of the interface after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique has been shown to be excellent, leading to results comparable to penetrating keratoplasty. However, there is little in the literature with respect to the controversy surrounding the preparation of the donor cornea. The purpose of this study was to evaluate visual acuity (VA) in patients with keratoconus who underwent DALK without removal of the donor graft endothelium...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28073689/corneo-scleral-contact-lens-in-a-piggyback-system-for-keratoconus-a-case-report
#2
Esteban Porcar, Juan Carlos Montalt, Enrique España-Gregori, Cristina Peris-Martínez
PURPOSE: We describe a case of fitting a corneo-scleral contact lens with a multi-aspheric geometry design (MAGD CScL) on top of a daily silicone hydrogel lens (piggyback system) for keratoconus management. METHODS: A 48-year-old man using soft toric contact lenses required an improvement in the unsatisfactory quality of his vision. He presented with bilateral asymmetric keratoconus with high myopia in the right eye (RE) and severe myopia in the left eye (LE). In addition, he had low vision in his LE because of a maculopathy...
January 7, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28067859/a-wirelessly-powered-smart-contact-lens-with-reconfigurable-wide-range-and-tunable-sensitivity-sensor-readout-circuitry
#3
Jin-Chern Chiou, Shun-Hsi Hsu, Yu-Chieh Huang, Guan-Ting Yeh, Wei-Ting Liou, Cheng-Kai Kuei
This study presented a wireless smart contact lens system that was composed of a reconfigurable capacitive sensor interface circuitry and wirelessly powered radio-frequency identification (RFID) addressable system for sensor control and data communication. In order to improve compliance and reduce user discomfort, a capacitive sensor was embedded on a soft contact lens of 200 μm thickness using commercially available bio-compatible lens material and a standard manufacturing process. The results indicated that the reconfigurable sensor interface achieved sensitivity and baseline tuning up to 120 pF while consuming only 110 μW power...
January 7, 2017: Sensors
https://www.readbyqxmd.com/read/28061510/bacterial-coaggregation-among-the-most-commonly-isolated-bacteria-from-contact-lens-cases
#4
Ananya Datta, Fiona Stapleton, Mark D P Willcox
Purpose: To examine the coaggregation and cohesion between the commonly isolated bacteria from contact lens cases. Methods: Four or five strains each of commonly isolated bacteria from contact lens cases, Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Serratia marcescens, were grown, washed, mixed in equal proportions, and allowed to coaggregate for 24 hours. Lactose (0.06 M), sucrose (0.06 M), and pronase (2 mg/mL; 2 hours, 37°C) were used to inhibit coaggregation...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28060146/combined-effect-of-ocular-and-multifocal-contact-lens-induced-aberrations-on-visual-performance-center-distance-versus-center-near-design
#5
Daniela Lopes-Ferreira, Paulo Fernandes, António Queirós, José M González-Meijome
PURPOSE: To evaluate the combined effects of inherent ocular aberrations and induced aberrations with a multifocal soft contact lens (MFCL) after 15 days of lens wear in presbyopic participants and their influence on visual performance at distance and near under high and low contrast conditions. METHODS: Forty presbyopic participants (mean age, 48.7±3.4) presenting a mean addition of 1.53±0.58 D were fitted with Biofinity Multifocal (CooperVision) and included in the study...
January 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28060062/pilot-study-of-corneal-sensitivity-and-its-association-in-keratoconus
#6
Preeji S Mandathara, Fiona J Stapleton, Jim Kokkinakis, Mark D P Willcox
PURPOSE: To evaluate corneal sensitivity and its association with other clinical parameters in keratoconus. METHODS: Twenty-four subjects with keratoconus aged between 18 and 65 years were recruited in this cross-sectional study. Ocular symptoms, corneal topography, tear variables such as tear osmolarity, volume and lower tear meniscus height, ocular surface staining, central sensitivity threshold (CST), and corneal subepithelial nerve mapping were obtained. Association between central CST and other clinical variables was examined using the Spearman correlation coefficient...
February 2017: Cornea
https://www.readbyqxmd.com/read/28059368/measurement-of-thickness-and-profile-of-a-transparent-material-using-fluorescent-stereo-microscopy
#7
Zhenxing Hu, Tingge Xu, Huiyang Luo, Rong Z Gan, Hongbing Lu
Full-field thickness measurement for a thin transparent film is of interest for biological, medical, electronic, and packaging materials. It is a challenging task when the film is curvy, delicate and its thickness varies with location. We report herein a method to measure the thickness of a transparent (flat or curved) material and its topography using a stereo fluorescent profilometry technique. In this technique, two different types of fluorescent particles are deposited to both sides of the transparent film...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28059302/replication-of-thermoplastic-polymer-spherical-lens-array-using-microforged-molding-technique
#8
Dan Xie, Xuefeng Chang, Xiayun Shu, Jian Wang, Lifang Mei, Shanming Luo
In this paper, we propose a replication method of thermoplastic polymer spherical lens array using a novel microforged mold. The Si<sub>3</sub>N<sub>4</sub> ceramic balls, with 3.5 mm diameter, 10 nm surface roughness and 84 nm deviation from spherical profile, were utilized as indentor to generate aluminum alloy lens array mold. Upon the optimization of technical parameters, such as heating and de-molding temperature, indentation force and holding time, a high quality spherical lens array mold was obtained...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28059290/self-calibration-single-lens-3d-video-extensometer-for-high-accuracy-and-real-time-strain-measurement
#9
Xinxing Shao, Mohammed Mokhtar Eisa, Zhenning Chen, Shuai Dong, Xiaoyuan He
The accuracy of strain measurement using a common optical extensometer with two-dimensional (2D) digital image correlation (DIC) is not sufficient for experimental applications due to the effect of out-of-plane motion. Although three-dimensional (3D) DIC can measure all three components of displacement without introducing in-plane displacement errors, 3D-DIC requires the stringent synchronization between two digital cameras and requires complicated system calibration of binocular stereovision, which makes the measurement rather inconvenient...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28057440/new-web-based-algorithm-to-improve-rigid-gas-permeable-contact-lens-fitting-in-keratoconus
#10
Sara Ortiz-Toquero, Guadalupe Rodriguez, Victoria de Juan, Raul Martin
PURPOSE: To calculate and validate a new web-based algorithm for selecting the back optic zone radius (BOZR) of spherical gas permeable (GP) lens in keratoconus eyes. METHODS: A retrospective calculation (n=35; multiple regression analysis) and a posterior prospective validation (new sample of 50 keratoconus eyes) of a new algorithm to select the BOZR of spherical KAKC design GP lenses (Conoptica) in keratoconus were conducted. BOZR calculated with the new algorithm, manufacturer guidelines and APEX software were compared with the BOZR that was finally prescribed...
January 2, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28053528/bottom-up-fabrication-of-zwitterionic-polymer-brushes-on-intraocular-lens-for-improved-biocompatibility
#11
Yuemei Han, Xu Xu, Junmei Tang, Chenghui Shen, Quankui Lin, Hao Chen
Intraocular lens (IOL) is an efficient implantable device commonly used for treating cataracts. However, bioadhesion of bacteria or residual lens epithelial cells on the IOL surface after surgery causes postoperative complications, such as endophthalmitis or posterior capsular opacification, and leads to loss of sight again. In the present study, zwitterionic polymer brushes were fabricated on the IOL surface via bottom-up grafting procedure. The attenuated total reflection-Fourier transform infrared and contact angle measurements indicated successful surface modification, as well as excellent hydrophilicity...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28053527/fabrication-of-nonfouling-bactericidal-and-bacteria-corpse-release-multifunctional-surface-through-surface-initiated-raft-polymerization
#12
Bailiang Wang, Zi Ye, Yihong Tang, Yuemei Han, Quankui Lin, Huihua Liu, Hao Chen, Kaihui Nan
Infections after surgery or endophthalmitis are potentially blinding complications caused by bacterial adhesion and subsequent biofilm formation on the intraocular lens. Neither single-function anti-adhesion surface nor contacting killing surface can exhibit ideal antibacterial function. In this work, a novel (2-(dimethylamino)-ethyl methacrylate-co-2-methacryloyloxyethyl phosphorylcholine) (p (DMAEMA-co-MPC)) brush was synthesized by "grafting from" method through reversible-addition fragmentation chain transfer polymerization...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28033160/substance-p-in-flush-tears-and-schirmer-strips-of-healthy-participants
#13
Maria Markoulli, Moneisha Gokhale, Jingjing You
PURPOSE: To determine the repeatability of the flush tear collection technique and the Schirmer strip for Substance P tear analysis. METHODS: The tears of 10 healthy non-contact-lens wearers were collected via Schirmer strip and microcapillary following instillation of either 20 μL (F-20) or 60 μL (F-60) of saline. Each technique was conducted on two occasions and in a randomized order. Total protein content (TPC) and Substance P concentrations were determined...
December 29, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28030882/ocular-response-to-environmental-variations-in-contact-lens-wearers
#14
Alberto López-de la Rosa, Vicente Martín-Montañez, Alberto López-Miguel, Itziar Fernández, Margarita Calonge, José M González-Méijome, María J González-García
PURPOSE: To assess the influence of different indoor environments simulated in an environmental chamber on soft contact lens (CL) wearers. METHODS: Fifty-four CL wearers were grouped based on their symptoms while wearing their CLs. Subjects were fitted with two different CL types, conventional hydrogel (Omafilcon A) and silicone hydrogel (comfilcon A), and exposed to two controlled indoor environmental conditions, standard [50% relative humidity (RH), 23°C, 930 mb of atmospheric pressure] and adverse (in-flight air cabin environment: 5% RH, localised air flow, 23°C, 750 mb atmospheric pressure), for 90 min in an environmental chamber, making a total of four visits...
January 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28028488/bilateral-ectopia-lentis-with-isolated-lens-coloboma-in-marfan-syndrome
#15
Sabin Sahu, Reena Yadav, Sharad Gupta, Lila Raj Puri
A rare case of bilateral ectopia lentis with isolated lens coloboma in Marfan syndrome is reported. A 21-year-old female presented with decreased vision in both eyes. Her unaided visual acuity was 20/200 and 20/400 in the right and left eye, respectively, improving to 20/40 with -4.5 DS/-3.0 DC x 10° correction in the right eye and 20/80 with -10.0 DS/-6.5 Dc x10° correction in the left eye. On slit lamp examination under mydriasis, both eyes revealed ectopia lentis with lens coloboma and stretched zonules...
2016: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28027493/hydrophilic-modification-of-intraocular-lens-via-surface-initiated-reversible-addition-fragmentation-chain-transfer-polymerization-for-reduced-posterior-capsular-opacification
#16
Quankui Lin, Junmei Tang, Yuemei Han, Xu Xu, Xiaojuan Hao, Hao Chen
Phacoemulsification followed with intraocular lens (IOL) implantation is the most effective clinical surgeries in treating cataracts. However, posterior capsular opacification (PCO), a common complication of this surgery, may cause vision decrease after surgery. PCO is mainly caused by the adhesion, proliferation and trans-differentiation of the residual lens epithelial cells (LEC) after surgery. Surface modification of IOL to reduce the LEC adhesion is of great importance in PCO prevention. Herein, surface initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization was utilized to modify the IOL materials for generating a comb-like polyethylene glycol (PEG) brush coating on the surface...
December 21, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28027276/accommodation-and-phoria-in-children-wearing-multifocal-contact-lenses
#17
Celia R Gong, David Troilo, Kathryn Richdale
PURPOSE: To determine the effect of multifocal contact lenses on accommodation and phoria in children. METHODS: This was a prospective, non-dispensing, randomized, crossover, single-visit study. Myopic children with normal accommodation and binocularity and no history of myopia control treatment were enrolled and fitted with CooperVision Biofinity single vision (SV) and multifocal (MF, +2.50D center distance add) contact lenses. Accommodative responses (photorefraction) and phorias (modified Thorington) were measured at four distances (>3 m, 100 cm, 40 cm, 25 cm)...
December 23, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28013522/methods-for-in-vivo-ex-vivo-analysis-of-antimicrobial-peptides-in-bacterial-keratitis-sirna-knockdown-colony-counts-myeloperoxidase-immunostaining-and-rt-pcr-assays
#18
Satya Sree Kolar, Hasna Baidouri, Maria Luisa Mangoni, Alison M McDermott
Antimicrobial peptides (AMPs) are essential components of the innate immune response. They have direct killing ability as well as immunomodulatory functions. Here, we describe techniques to identify specific AMPs involved in the protection against microbial keratitis, a vision threatening infection of the cornea of the eye which is the most serious complication of contact lens wear. Specifically we detail the use of siRNA technology to temporarily knockdown AMP expression at the murine ocular surface in vivo and then describe ex vivo assays to determine the level of bacteria, relative number of neutrophils, and levels of cytokines, chemokines, and AMPs in infected corneas...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28009794/ocular-straylight-with-different-multifocal-contact-lenses
#19
Grzegorz Łabuz, Norberto López-Gil, Thomas J T P van den Berg, Fernando Vargas-Martín
PURPOSE: Multifocal contact lenses have been growing in popularity as a modality to correct presbyopic eyes, although visual side effects such as disability glare have been reported. The objective of this study was to investigate the effect of multifocal contact lenses on disability glare by means of ocular straylight. METHODS: A prospective randomized, comparative study was performed that included 16 subjects free of ocular pathology. Straylight was measured using a commercial straylight meter with the natural and dilated pupil...
December 22, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28007108/comparison-of-the-rate-of-refractive-growth-in-aphakic-eyes-versus-pseudophakic-eyes-in-the-infant-aphakia-treatment-study
#20
Scott R Lambert, George Cotsonis, Lindreth DuBois, M Edward Wilson, David A Plager, Edward G Buckley, Scott K McClatchey
PURPOSE: To compare the rate of refractive growth (RRG) between aphakic eyes and pseudophakic eyes in the Infant Aphakia Treatment Study (IATS). SETTING: Twelve clinical sites across the United States. DESIGN: Randomized clinical trial. METHODS: Patients randomized to unilateral cataract extraction with contact lens correction versus intraocular lens (IOL) implantation in the IATS had their rate of refractive growth (RRG3) calculated based on the change in refraction from the 1-month postoperative examination to age 5 years...
December 2016: Journal of Cataract and Refractive Surgery
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