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Mitsutoshi Miyasaka, Daisuke Tsurumaru, Yusuke Nishimuta, Yoshiki Asayama, Satoshi Kawanami, Eiji Oki, Minako Hirahashi, Hiroshi Honda
OBJECTIVE: To investigate the feasibility of diagnosing the invasion depth of early colorectal cancer (CRC) by quantitatively evaluating the basal indentation (BI)-i.e., the intestinal lateral deformity-in CT colonography (CTC). MATERIALS AND METHODS: 34 early CRCs (13 Tis CRCs and 21 T1 CRCs) in 32 patients who underwent a preoperative CTC were retrospectively examined. Two radiologists calculated the depth of the BI on a computed tomographic air-contrast enema (CT enema) image, the depth of the BI due to the geometric function (BI-G) on a cross-sectional multiplanar reconstruction (CS-MPR) image, and the ratio of the BI to the BI-G (i...
October 7, 2016: Japanese Journal of Radiology
Teruaki Iwano, Koichi Nagata, Atsushi Mima, Takashi Egawa, Hideyo Yamashita, Hiroshi Saito
No abstract text is available yet for this article.
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
A Racca, E Biscaldi, V Remorgida, U Leone Roberti Maggiore, V G Vellone, P L Venturini, S Ferrero
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
(no author information available yet)
No abstract text is available yet for this article.
October 2016: Endoscopy
Hidenori Kanazawa, Kenichi Utano, Shigeyoshi Kijima, Takahiro Sasaki, Yasuyuki Miyakura, Hisanaga Horie, Alan Kawarai Lefor, Hideharu Sugimoto
INTRODUCTION: An accurate assessment of the depth of tumor invasion in patients with colon cancer is an important part of the preoperative evaluation. Whether computed tomographic colonography (CTC) or optical colonoscopy (OC) is better to accurately determine tumor location and invasion depth has not been definitively determined. The aim of this study was to determine the diagnostic accuracy of tumor localization and tumor invasion depth of colon cancer by preoperative OC alone or combined with CTC...
September 21, 2016: Asian Journal of Endoscopic Surgery
Elizabeth Sheena John, Ann M John, David R Hansberry, Prashant J Thomas, Prateek Agarwal, Christopher Deitch, Sita Chokhavatia
PURPOSE: Patients screened for colorectal cancer (CRC) frequently turn to the Internet to improve their understanding of tests used for detection, including colonoscopy, flexible sigmoidoscopy, fecal occult blood test (FOBT), and CT colonography. It was of interest to determine the quality and readability levels of online health information. METHODS: The screening tools were googled, and the top 20 results of each test were analyzed for readability, accessibility, usability, and reliability...
September 20, 2016: International Journal of Colorectal Disease
Nicola Flor, Simone Soldi, Edoardo Zanchetta, Sara Sbaraini, Filippo Pesapane
Different scenarios embrace computed tomography imaging and diverticula, including asymptomatic (diverticulosis) and symptomatic patients (acute diverticulitis, follow-up of acute diverticulitis, chronic diverticulitis). If the role of computed tomography is validated and widely supported by evidence in case of acute diverticulitis, this is not the case of patients in their follow-up for acute diverticulitis or with symptoms related to diverticula, but without acute inflammation. In these settings, computed tomography colonography is gaining consensus as the preferred radiologic test...
October 2016: Journal of Clinical Gastroenterology
Bernardette Bonello, Alex Ghanouni, Harriet L Bowyer, Eilidh MacRae, Wendy Atkin, Stephen P Halloran, Jane Wardle, Christian von Wagner
BACKGROUND: To assess public preferences for colorectal cancer (CRC) surveillance tests for intermediate-risk adenomas, using a hypothetical scenario. METHODS: Adults aged 45-54 years without CRC were identified from three General Practices in England (two in Cumbria, one in London). A postal survey was carried out during a separate study on preferences for different first-line CRC screening modalities (non- or full-laxative computed tomographic colonography, flexible sigmoidoscopy, or colonoscopy)...
2016: BMC Gastroenterology
Chelsie K Sievers, Luli S Zou, Perry J Pickhardt, Kristina A Matkowskyj, Dawn M Albrecht, Linda Clipson, Jeffery W Bacher, B Dustin Pooler, Fouad J Moawad, Brooks D Cash, Mark Reichelderfer, Tien N Vo, Michael A Newton, Bret R Larget, Richard B Halberg
OBJECTIVE AND DESIGN: The goal of the study was to determine whether the mutational profile of early colorectal polyps correlated with growth behaviour. The growth of small polyps (6-9 mm) that were first identified during routine screening of patients was monitored over time by interval imaging with CT colonography. Mutations in these lesions with known growth rates were identified by targeted next-generation sequencing. The timing of mutational events was estimated using computer modelling and statistical inference considering several parameters including allele frequency and fitness...
September 8, 2016: Gut
Kenichi Utano, Koichi Nagata, Tetsuro Honda, Toru Mitsushima, Takaaki Yasuda, Takashi Kato, Shoichi Horita, Michio Asano, Noritaka Oda, Kenichiro Majima, Yasutaka Kawamura, Michiaki Hirayama, Naoki Watanabe, Hidenori Kanazawa, Alan Kawarai Lefor, Hideharu Sugimoto
Purpose To evaluate the diagnostic accuracy and patient acceptance of reduced-laxative computed tomographic (CT) colonography without computer-aided detection (CAD) for the detection of colorectal polypoid and non-polypoid neoplasms in a population with a positive recent fecal immunochemical test (FIT). Materials and Methods Institutional review board approval and written informed consent were obtained. This multicenter prospective trial enrolled patients who had positive FIT results. Reduced-laxative CT colonography and colonoscopy were performed on the same day...
August 31, 2016: Radiology
Perry J Pickhardt, B Dustin Pooler, Ifeanyi Mbah, Jennifer M Weiss, David H Kim
Purpose To determine the rate and types of polyps detected at repeat computed tomographic (CT) colonography screening after initial negative findings at CT colonography screening. Materials and Methods Among 5640 negative CT colonography screenings (no polyps ≥ 6 mm) performed before 2010 at one medical center, 1429 (25.3%; mean age, 61.4 years; 736 women, 693 men) patients have returned for repeat CT colonography screening (mean interval, 5.7 years ± 0.9; range, 4.5-10.7 years). Positive rates and histologic findings of initial and repeat screening were compared in this HIPAA-compliant, institutional review board-approved study...
August 22, 2016: Radiology
Lapo Sali, Daniele Regge
CT colonography (CTC) is a minimally invasive radiological investigation of the colon. Robust evidence indicates that CTC is safe, well tolerated and highly accurate for the detection of colorectal cancer (CRC) and large polyps, which are the targets of screening. Randomised controlled trials were carried out in Europe to evaluate CTC as primary test for population screening of CRC in comparison with faecal immunochemical test (FIT), sigmoidoscopy and colonoscopy. Main outcomes were participation rate and detection rate...
August 19, 2016: British Journal of Radiology
Gerritt M Lagemann, Patrick W Aldred, Amir A Borhani, Anish Ghodadra, Vikas Agarwal
OBJECTIVE: Planning imaging performed during CT-guided procedures may occasionally contain important incidental findings. The purpose of this study was to identify and characterize by clinical relevance the extraspinal findings detected on planning imaging for CT-guided lumbar transforaminal epidural steroid injections (TFESIs). MATERIALS AND METHODS: Four radiologists retrospectively evaluated the planning scout views and CT studies for 488 consecutive CT-guided lumbar TFESIs performed in 400 patients over a 1-year period...
August 17, 2016: AJR. American Journal of Roentgenology
B Dustin Pooler, David H Kim, Perry J Pickhardt
OBJECTIVE: The purpose of this study was to analyze the incidence and outcomes of unsuspected indeterminate but likely unimportant extracolonic findings (CT Colonography Reporting and Data System [C-RADS] category E3) at screening CT colonography (CTC). MATERIALS AND METHODS: Over 99 months (April 2004 through June 2012), 7952 consecutive adults without symptoms of colorectal cancer (4277 women, 3675 men; mean age ± SD, 56.7 ± 7.3 years) underwent first-time screening CTC...
November 2016: AJR. American Journal of Roentgenology
Elias Nerad, Max J Lahaye, Monique Maas, Patty Nelemans, Frans C H Bakers, Geerard L Beets, Regina G H Beets-Tan
OBJECTIVE: The purpose of this article is to determine the accuracy of CT in the detection of tumor invasion beyond the bowel wall and nodal involvement of colon carcinomas. A literature search was performed to identify studies describing the accuracy of CT in the staging of colon carcinomas. Studies including rectal carcinomas that were inseparable from colon carcinomas were excluded. Publication bias was explored by using a Deeks funnel plot asymmetry test. A hierarchic summary ROC model was used to construct a summary ROC curve and to calculate summary estimates of sensitivity, specificity, and diagnostic odds ratios (ORs)...
November 2016: AJR. American Journal of Roentgenology
Prasanna L Ponugoti, Oscar W Cummings, Douglas K Rex
The prevalence of cancer in small and diminutive polyps is relevant to "resect and discard" and CT colonography reporting recommendations. We evaluated a prospectively collected colonoscopy polyp database to identify polyps <10mm and those with cancer or advanced histology (high-grade dysplasia or villous elements). Of 32,790 colonoscopies, 15,558 colonoscopies detected 42,630 polyps <10mm in size. A total of 4790 lesions were excluded as they were not conventional adenomas or serrated class lesions. There were 23,524 conventional adenomas <10mm of which 22,952 were tubular adenomas...
June 28, 2016: Digestive and Liver Disease
Andrew A Plumb, Claire Nickerson, Katherine Wooldrage, Paul Bassett, Stuart A Taylor, Douglas Altman, Wendy Atkin, Steve Halligan
BACKGROUND AND STUDY AIMS: Terminal digit preference bias for "pleasing" numbers has been described in many areas of medicine. The aim of this study was to determine whether endoscopists, radiologists, and pathologists exhibit such bias when measuring colorectal polyp diameters. METHODS: Colorectal polyp diameters measured at endoscopy, computed tomographic colonography (CTC), and histopathology were collated from a colorectal cancer screening program and two parallel multicenter randomized trials...
October 2016: Endoscopy
Masahiro Oda, Hiroaki Kondo, Takayuki Kitasaka, Kazuhiro Furukawa, Ryoji Miyahara, Yoshiki Hirooka, Hidemi Goto, Nassir Navab, Kensaku Mori
PURPOSE: Polyps found during CT colonography can be removed by colonoscopic polypectomy. A colonoscope navigation system that navigates a physician to polyp positions while performing the colonoscopic polypectomy is required. Colonoscope tracking methods are essential for implementing colonoscope navigation systems. Previous colonoscope tracking methods have failed when the colon deforms during colonoscope insertions. This paper proposes a colonoscope tracking method that is robust against colon deformations...
July 18, 2016: International Journal of Computer Assisted Radiology and Surgery
Lapo Sali, Leonardo Ventura, Mario Mascalchi, Massimo Falchini, Paola Mantellini, Silvia Delsanto, Stefano Milani, Marco Zappa, Grazia Grazzini
The aim of this study was to evaluate the participation and yield of the faecal immunochemical test (FIT) in nonattendees for computed tomography colonography (CTC) or optical colonoscopy (OC) screening, in the setting of a randomized trial. In the SAVE trial, 16087 individuals were randomly assigned and invited to one of four interventions for colorectal cancer screening: (i) biennial FIT for three rounds; (ii) reduced-preparation CTC; (iii) full-preparation CTC; and (iv) OC. Nonattendees of reduced-preparation CTC, full-preparation CTC and OC groups were invited to FIT...
July 15, 2016: European Journal of Cancer Prevention
David H Kim, Kristina A Matkowskyj, Perry J Pickhardt
No abstract text is available yet for this article.
August 2016: Abdominal Radiology
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