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https://www.readbyqxmd.com/read/27911113/a-tribute-to-professor-steven-l-wechsler-1948-2016-the-man-and-the-scientist
#1
Anthony B Nesburn, Lbachir BenMohamed
Professor Steven L. Wechsler, a world-renowned eye researcher and virologist, passed away unexpectedly on June 12, 2016 at the age of 68. Many scientists came to know Professor Wechsler as a gifted researcher in the field of ocular Herpes Simplex Virus (HSV-1) latency, reactivation, and pathogenesis. Professor Wechsler published over 150 peer-reviewed scientific papers during his career, pushing forward the frontiers of his field eye research. His colleagues would say, 'Steve literally wrote the book on herpes latency and reactivation...
December 2, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27906999/identification-geochemical-characterisation-and-significance-of-bitumen-among-the-grave-goods-of-the-7th-century-mound-1-ship-burial-at-sutton-hoo-suffolk-uk
#2
Pauline Burger, Rebecca J Stacey, Stephen A Bowden, Marei Hacke, John Parnell
The 7th century ship-burial at Sutton Hoo is famous for the spectacular treasure discovered when it was first excavated in 1939. The finds include gold and garnet jewellery, silverware, coins and ceremonial armour of broad geographical provenance which make a vital contribution to understanding the political landscape of early medieval Northern Europe. Fragments of black organic material found scattered within the burial were originally identified as 'Stockholm Tar' and linked to waterproofing and maintenance of the ship...
2016: PloS One
https://www.readbyqxmd.com/read/27899635/interpro-in-2017-beyond-protein-family-and-domain-annotations
#3
Robert D Finn, Teresa K Attwood, Patricia C Babbitt, Alex Bateman, Peer Bork, Alan J Bridge, Hsin-Yu Chang, Zsuzsanna Dosztányi, Sara El-Gebali, Matthew Fraser, Julian Gough, David Haft, Gemma L Holliday, Hongzhan Huang, Xiaosong Huang, Ivica Letunic, Rodrigo Lopez, Shennan Lu, Aron Marchler-Bauer, Huaiyu Mi, Jaina Mistry, Darren A Natale, Marco Necci, Gift Nuka, Christine A Orengo, Youngmi Park, Sebastien Pesseat, Damiano Piovesan, Simon C Potter, Neil D Rawlings, Nicole Redaschi, Lorna Richardson, Catherine Rivoire, Amaia Sangrador-Vegas, Christian Sigrist, Ian Sillitoe, Ben Smithers, Silvano Squizzato, Granger Sutton, Narmada Thanki, Paul D Thomas, Silvio C E Tosatto, Cathy H Wu, Ioannis Xenarios, Lai-Su Yeh, Siew-Yit Young, Alex L Mitchell
InterPro (http://www.ebi.ac.uk/interpro/) is a freely available database used to classify protein sequences into families and to predict the presence of important domains and sites. InterProScan is the underlying software that allows both protein and nucleic acid sequences to be searched against InterPro's predictive models, which are provided by its member databases. Here, we report recent developments with InterPro and its associated software, including the addition of two new databases (SFLD and CDD), and the functionality to include residue-level annotation and prediction of intrinsic disorder...
November 29, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27894162/partitioning-the-effects-of-mating-and-nuptial-feeding-on-the-microbiome-in-gift-giving-insects
#4
Chad C Smith, Robert B Srygley, Emma I Dietrich, Ulrich G Mueller
Mating is a ubiquitous social interaction with the potential to influence the microbiome by facilitating transmission, modifying host physiology, and in species where males donate nuptial gifts to females, altering diet. We manipulated mating and nuptial gift consumption in two insects that differ in nuptial gift size, the Mormon cricket Anabrus simplex and the decorated cricket Gryllodes sigillatus, with the expectation that larger gifts are more likely to affect the gut microbiome. Surprisingly, mating, but not nuptial gift consumption, affected the structure of bacterial communities in the gut, and only in Mormon crickets...
November 28, 2016: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/27893593/trends-in-selected-measures-of-racial-and-ethnic-disparities-in-gonorrhea-and-syphilis-in-the-united-states-1981-2013
#5
Harrell W Chesson, Chirag G Patel, Thomas L Gift, Sevgi O Aral
BACKGROUND: The purpose of this study was to examine selected measures of racial and ethnic disparities in the reported incidence of syphilis and gonorrhea from 1981 to 2013 in the United States. METHODS: For each year, from 1981 to 2013, we calculated values for 5 disparity measures (Gini coefficient, 2 versions of the index of disparity, population attributable proportion, and the black-to-white rate ratio) for 5 racial/ethnic categories (non-Hispanic white, non-Hispanic black, Hispanic, American Indian/Alaska Native, and Asian/Pacific Islander)...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27893315/presidential-address-2016-re-membering-the-gifts-of-professional
#6
Bill Gaventa
No abstract text is available yet for this article.
December 2016: Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/27891235/interaction-and-medical-inducement-between-pharmaceutical-representatives-and-physicians-a-meta-synthesis
#7
REVIEW
Shahrzad Salmasi, Long Chiau Ming, Tahir Mehmood Khan
BACKGROUND: It has been proven that the interaction between pharmaceutical representatives and physicians can directly influence the latter's prescribing behaviour. This meta-synthesis aims to explore the available studies regarding the nature of the interaction that takes place between pharmaceutical representatives and physicians. It highlights the different aspects of that interaction by investigating the reasons why these meetings happen in the first place, their benefits and drawbacks and their impact on patients' health and, ultimately, the health of the public...
2016: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/27889381/do-developmental-milestones-at-4-8-12-and-24-months-predict-iq-at-5-6-years-old-results-of-the-eden-mother-child-cohort
#8
Hugo Peyre, Marie-Laure Charkaluk, Anne Forhan, Barbara Heude, Franck Ramus
RATIONALE: The present study aims: (i) to determine how well developmental milestones at 4, 8, 12 and 24 months may predict IQ at 5-6 years old, (ii) to identify cognitive domains during the first two years that best predict later IQ and (iii) to determine whether children with IQ in the normal range at 5-6 years old may differ from disabled (IQ < 70) and gifted children (IQ > 130) with regard to their early cognitive development. METHOD: The main developmental milestones were collected through self-administered questionnaires rated by parents at 4, 8, 12 and 24 months and through parental questionnaires administered by a trained interviewer and questionnaires completed following a medical examination at 12 months...
November 15, 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27883316/to-accept-or-refuse-patient-s-gift-in-money-and-how-case-report-with-review
#9
Vesna Kos
This report describes a (rare) situation when a patient's first gift to a young doctor was in money. This happened in very specific circumstances - in a refugee camp during the War in Croatia. The data are taken from a large study on gifts, conducted on a representative sample of Croatian general practitioners (GPs), N = 265, from 2358 in total. Pro and contra factors are discussed, considering tradition and customs, but also a lack of knowledge of young doctors in handling gifts in general. The intention of this report is primarily educative, with review of (scarce) literature, and recommendations, where the generally accepted rules might have exceptions...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27882649/impact-of-male-condition-on-his-spermatophore-and-consequences-for-female-reproductive-performance-in-the-glanville-fritillary-butterfly
#10
Anne Duplouy, Luisa Woestmann, Juan Gallego-Zamorano, Marjo Saastamoinen
In butterflies, male reproductive success is highly related to the quality and the size of the spermatophore transferred to the female. The spermatophore is a capsule produced by the male during copulation, which in many species contains sperm in addition to a nuptial gift, and which is digested by the female after copulation. The nuptial gift may contribute to egg production and offspring quality, and in some cases also to female body maintenance. The production of the spermatophore, however, represents a cost for the male and, in polyandrous species, ejaculates are sometimes allocated adaptively across matings...
November 24, 2016: Insect Science
https://www.readbyqxmd.com/read/27873139/when-marcel-mauss-s-essai-sur-le-don-becomes-the-gift-variations-on-the-theme-of-solidarity
#11
Simone Bateman
Since the early 1970s, Marcel Mauss's Essai sur le Don (1923), translated into English as The Gift in 1954, has been a standard reference in the social science and bioethical literature on the use of human body parts and substances for medical and research purposes. At that time, three social scientists-political scientist Richard Titmuss in the United Kingdom and sociologist Renée C. Fox working with historian Judith Swazey in the United States-had the idea of using this concept to highlight the fundamental structure of the biomedical practices they were studying, respectively, blood donation, and hemodialysis and organ transplantation...
November 21, 2016: Theoretical Medicine and Bioethics
https://www.readbyqxmd.com/read/27864411/commentary-increasing-uptake-of-hiv-testing-gifts-are-good-but-more-is-needed
#12
Nathan Ford, Edward J Mills
No abstract text is available yet for this article.
November 17, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27863914/cultural-aspects-and-mythologies-surrounding-menstruation-and-abnormal-uterine-bleeding
#13
REVIEW
Delfin A Tan, Rohana Haththotuwa, Ian S Fraser
The objective of this chapter is to present an overview of how menstruation, a normal bodily function, was and is perceived in various ethnic groups and cultures in the world, from ancient mythology, historical, or traditional practices to contemporary belief systems. Mythical tales about menstruation abound in the legends and prehistory of ancient cultures. These tales characterize menstrual blood variously as sacred, a gift from the gods, or a punishment for sin, but it is almost always magical and powerful...
October 26, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27859000/dynamic-testing-and-test-anxiety-amongst-gifted-and-average-ability-children
#14
Bart Vogelaar, Merel Bakker, Julian G Elliott, Wilma C M Resing
BACKGROUND: Dynamic testing has been proposed as a testing approach that is less disadvantageous for children who may be potentially subject to bias when undertaking conventional assessments. For example, those who encounter high levels of test anxiety, or who are unfamiliar with standardized test procedures, may fail to demonstrate their true potential or capabilities. While dynamic testing has proven particularly useful for special groups of children, it has rarely been used with gifted children...
November 17, 2016: British Journal of Educational Psychology
https://www.readbyqxmd.com/read/27856741/universal-screening-increases-the-representation-of-low-income-and-minority-students-in-gifted-education
#15
David Card, Laura Giuliano
Low-income and minority students are substantially underrepresented in gifted education programs. The disparities persist despite efforts by many states and school districts to broaden participation through changes in their eligibility criteria. One explanation for the persistent gap is that standard processes for identifying gifted students, which are based largely on the referrals of parents and teachers, tend to miss qualified students from underrepresented groups. We study this hypothesis using the experiences of a large urban school district following the introduction of a universal screening program for second graders...
November 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27856353/urolithiasis-in-renal-transplant-donors-and-recipients-an-update
#16
REVIEW
Ahmed M Harraz, Ahmed I Kamal, Ahmed A Shokeir
Urolithiasis in the context of renal transplant is a quite rare event that requires keeping a higher index of suspicion and vigilance. Donors with incidentally discovered asymptomatic renal stones "donor gifted lithiasis" are potentially considered for donation should they are not recurrent stone formers and in the absence of active biochemical disorders. Stone clearance from the donors can be done before donation using shock wave lithotripsy and/or flexible ureteroscopy. Ex vivo ureteroscopy at time of transplant is equally feasible and safe...
November 14, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27856120/gifts-and-influence-conflict-of-interest-policies-and-prescribing-of-psychotropic-medications-in-the-united-states
#17
Marissa King, Peter S Bearman
The pharmaceutical industry spends roughly 15 billion dollars annually on detailing - providing gifts, information, samples, trips, honoraria and other inducements - to physicians in order to encourage them to prescribe their drugs. In response, several states in the United States adopted policies that restrict detailing. Some states banned gifts from pharmaceutical companies to doctors, other states simply required physicians to disclose the gifts they receive, while most states allowed unrestricted detailing...
November 9, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27855320/mir-122-promotes-hepatic-antioxidant-defense-of-genetically-improved-farmed-tilapia-gift-oreochromis-niloticus-exposed-to-cadmium-by-directly-targeting-a-metallothionein-gene
#18
Jun Qiang, Yi-Fan Tao, Jie He, Pao Xu, Jin-Wen Bao, Yi-Lan Sun
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate target gene expression by binding to the 3'untranslated region (3'UTR) of the target mRNA. MiRNAs regulate a large variety of genes, including those involved in liver homeostasis and energy metabolism. Down-regulated levels of hepatic miR-122 were found in genetically improved farmed tilapia (GIFT, Oreochromis niloticus) exposed to cadmium (Cd) stress. Here, we report for the first time that reduction of miR-122 post-transcriptionally increased metallothionein (MT) mRNA levels by binding to its 3'UTR, as shown by a 3' UTR luciferase reporter assay...
November 9, 2016: Aquatic Toxicology
https://www.readbyqxmd.com/read/27854261/taking-advantage-of-nature-s-gift-can-endogenous-neural-stem-cells-improve-myelin-regeneration
#19
REVIEW
Rainer Akkermann, Janusz Joachim Jadasz, Kasum Azim, Patrick Küry
Irreversible functional deficits in multiple sclerosis (MS) are directly correlated to axonal damage and loss. Neurodegeneration results from immune-mediated destruction of myelin sheaths and subsequent axonal demyelination. Importantly, oligodendrocytes, the myelinating glial cells of the central nervous system, can be replaced to some extent to generate new myelin sheaths. This endogenous regeneration capacity has so far mainly been attributed to the activation and recruitment of resident oligodendroglial precursor cells...
November 14, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27853299/the-archaeal-7%C3%A2-kda-dna-binding-proteins-extended-characterization-of-an-old-gifted-family
#20
Valentina Kalichuk, Ghislaine Béhar, Axelle Renodon-Cornière, Georgi Danovski, Gonzalo Obal, Jacques Barbet, Barbara Mouratou, Frédéric Pecorari
The "7 kDa DNA-binding" family, also known as the Sul7d family, is composed of chromatin proteins from the Sulfolobales archaeal order. Among them, Sac7d and Sso7d have been the focus of several studies with some characterization of their properties. Here, we studied eleven other proteins alongside Sac7d and Sso7d under the same conditions. The dissociation constants of the purified proteins for binding to double-stranded DNA (dsDNA) were determined in phosphate-buffered saline at 25 °C and were in the range from 11 μM to 22 μM with a preference for G/C rich sequences...
November 17, 2016: Scientific Reports
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