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https://www.readbyqxmd.com/read/29165586/extent-of-physician-pharmaceutical-industry-interactions-in-low-and-middle-income-countries-a-systematic-review
#1
Racha Fadlallah, Lina Alkhaled, Hneine Brax, Mayse Nasser, Mhd Hashem Rajabbik, Hala Nass, Lara A Kahale, Elie A Akl
Background: Pharmaceutical companies spend large amounts of money promoting their products to physicians. There is evidence that physicians' interactions with pharmaceutical companies negatively affect their prescribing patterns. The objective of this study was to systematically review the extent of the relationship between physicians and pharmaceutical companies in low- and middle-income countries (LMICs). Methods: Studies assessing the extent of any type of interaction between practicing physicians and pharmaceutical companies were eligible...
November 20, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29164505/network-level-dysconnectivity-in-patients-with-nasopharyngeal-carcinoma-npc-early-post-radiotherapy-longitudinal-resting-state-fmri-study
#2
Yingwei Qiu, Zheng Guo, Lujun Han, Yadi Yang, Jing Li, Shiliang Liu, Xiaofei Lv
In this study, we seek to longitudinally investigate the network-level functional connectivity (FC) alternations and its association with irradiation dose and cognition changes in the early stage post radiotherapy (RT) in nasopharyngeal carcinoma (NPC) patients. We performed independent component analysis (ICA) of resting state blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) from 39 newly diagnosed NPC patients before receiving treatment (baseline), and 3 months post-RT. the default mode network (DMN), salience network (SN), and executive control network (ECN) were extracted with well-validated software (GIFT)...
November 21, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29155891/the-burden-of-gynecomastia-among-men-on-antiretroviral-therapy-in-zomba-malawi
#3
Victor Singano, Alemayehu Amberbir, Daniela Garone, Christopher Kandionamaso, Jack Msonko, Monique van Lettow, Kondwani Kalima, Yamikani Mataka, Gift Kawalazira, Gabriel Mateyu, Aunex Kwekwesa, Alfred Matengeni, Joep J van Oosterhout
BACKGROUND: Many Africans who are on life-saving ART face challenges from a variety of toxicities. After the introduction of a standardized first-line efavirenz-containing ART regimen, reports of gynecomastia appeared in Malawian popular media, however data on the prevalence and risk factors of gynecomastia from Africa are lacking. METHODS: We conducted a cross-sectional study in males ≥18 years registered on ART at the HIV clinic in Zomba Central Hospital. Men who reported to have ever experienced breast or nipple enlargement received a standard questionnaire and underwent physical examination...
2017: PloS One
https://www.readbyqxmd.com/read/29152677/adhd-and-anxiety-clinical-significance-and-treatment-implications
#4
REVIEW
Frederick W Reimherr, Barrie K Marchant, Thomas E Gift, Tammy A Steans
In comparison to the DSM formulation of ADHD, we have proposed that ADHD in adults should be divided into Inattentive and Emotional Dysregulation Presentations. Under both systems, there is potential overlap with generalized anxiety disorder (GAD). We compared data from four distinct populations: ADHD clinical trials, GAD clinical trials, an ADHD clinic, and a forensic clinic. Approximately 25% of patients in each population had comorbid ADHD and anxiety. Comorbid subjects reported more childhood ADHD symptoms and higher scores on ADHD scales and were more likely to fit criteria for ADHD Emotional Dysregulation Presentation or DSM-IV combined type...
November 20, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29149132/lifelong-impression-remembering-one-of-our-own-during-the-holiday-season%C3%A2
#5
Mai-Fung Ho-Law
In life, meeting someone who truly possesses the gift of teaching is a blessing. As an exceptional mentor and role model, this person will inspire us to be the best that we can be and make us want to be better human beings. As oncology nurses, we have the honor of caring for patients who have been devastated by the diagnosis of cancer. Establishing deep connections with some of these patients will enrich and give more meaning to our own lives. 
.
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29148985/subtyping-sub-saharan-esophageal-squamous-cell-carcinoma-by-comprehensive-molecular-analysis
#6
Wenjin Liu, Jeff M Snell, William R Jeck, Katherine A Hoadley, Matthew D Wilkerson, Joel S Parker, Nirali Patel, Yohannie B Mlombe, Gift Mulima, N George Liomba, Lindsey L Wolf, Carol G Shores, Satish Gopal, Norman E Sharpless
No abstract text is available yet for this article.
November 16, 2017: JCI Insight
https://www.readbyqxmd.com/read/29144222/child-language-and-parenting-antecedents-and-externalizing-outcomes-of-emotion-regulation-pathways-across-early-childhood-a-person-centered-approach
#7
Jason José Bendezú, Pamela M Cole, Patricia Z Tan, Laura Marie Armstrong, Elizabeth B Reitz, Rachel M Wolf
Decreases in children's anger reactivity because of the onset of their autonomous use of strategies characterizes the prevailing model of the development of emotion regulation in early childhood (Kopp, 1989). There is, however, limited evidence of the varied pathways that mark this development and their proposed antecedents and consequences. This study used a person-centered approach to identify such pathways, antecedents, and outcomes. A sample of 120 children from economically strained rural and semirural households were observed while waiting to open a gift at ages 24, 36, and 48 months...
November 16, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29136448/the-greatest-gift-how-a-patient-s-death-taught-me-to-be-a-physician
#8
Lawrence I Kaplan
No abstract text is available yet for this article.
November 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29132284/love-matters-exploring-conceptions-of-love-in-rwanda-and-swaziland-and-relationship-to-hiv-and-intimate-partner-violence
#9
Allison Ruark, Erin Stern, Thandeka Dlamini-Simelane, Marie Fidele Kakuze
Health risks such as intimate partner violence (IPV) and HIV infection often occur within intimate sexual relationships, yet the study of love and intimacy is largely absent from health research on African populations. This study explores how women and men in Rwanda and Swaziland understand and represent love in their intimate sexual partnerships. In Rwanda, 58 in-depth interviews with 15 couples, 12 interviews with activists, and 24 focus group discussions were carried out during formative and evaluative research of the Indashyikirwa programme, which aims to reduce IPV and support healthy couple relationships...
December 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/29127734/population-representation-among-anatomical-donors-and-the-implication-for-medical-student-education
#10
Amanda J Collins, Whitney Smith, Eustathia Lela Giannaris, Elizabeth Orvek, Peter Lazar, Jan K Carney, Anne M Gilroy, Max P Rosen
INTRODUCTION: Dissection provides a unique opportunity to integrate anatomical and clinical education. Commonly, cadavers are randomly assigned to courses, which may result in skewed representation of patient populations. The primary aim of this study was to determine if the anatomical donors studied by students at Medical School (MS) accurately represent the disease burden of the local patient population. MATERIALS AND METHODS: This cross-sectional study compared Medical Center patient claims data and body donation data from the Anatomical Gift Program (AGP)...
November 11, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29126079/self-control-parenting-and-problem-behavior-in-early-childhood-a-multi-method-multi-informant-study
#11
Dionne L van Prooijen, Roos Hutteman, Hanna Mulder, Marcel A G van Aken, Odilia M Laceulle
BACKGROUND: Early childhood self-control and parenting are suggested to play key roles in the development of child problem behavior. The current study aims to 1) replicate earlier work by examining the unique and combined effects of child self-control and parenting on child problem behavior and 2) extend earlier work by including both mother and father reports. METHODS: Data were used from 107 Dutch families: mothers, fathers, and their two-year old child. Child self-control was measured using both father's and mother's reports of effortful control and with an observed behavioral task (i...
November 7, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/29125935/going-viral-in-png-exploring-routes-and-circumstances-of-entry-of-a-rabies-infected-dog-into-papua-new-guinea
#12
Victoria J Brookes, Chris Degeling, Michael P Ward
In this qualitative study implemented in November 2016, we elicited narratives about fictional rabies incursions from key employees (n = 16) of the National Agriculture and Quarantine Inspection Authority in Papua New Guinea (PNG) to explore the potential circumstances and routes of entry of a rabies-infected dog, and direct rabies preparedness. Although PNG is rabies free, proximity to rabies-endemic Indonesia poses a risk of introduction and it is expected that an outbreak in PNG would have devastating human health impacts consistent with other countries with similarly low human development indices and abundant free-roaming dogs...
November 6, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29118725/cognitive-and-neural-correlates-of-mathematical-giftedness-in-adults-and-children-a-review
#13
REVIEW
Timothy Myers, Emma Carey, Dénes Szűcs
Most mathematical cognition research has focused on understanding normal adult function and child development as well as mildly and moderately impaired mathematical skill, often labeled developmental dyscalculia and/or mathematical learning disability. In contrast, much less research is available on cognitive and neural correlates of gifted/excellent mathematical knowledge in adults and children. In order to facilitate further inquiry into this area, here we review 40 available studies, which examine the cognitive and neural basis of gifted mathematics...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29117201/whole-exome-sequencing-in-thrombophilic-pedigrees-to-identify-genetic-risk-factors-for-venous-thromboembolism
#14
Marisa L R Cunha, Joost C M Meijers, Frits R Rosendaal, Astrid van Hylckama Vlieg, Pieter H Reitsma, Saskia Middeldorp
BACKGROUND: Family studies have shown a strong heritability component for venous thromboembolism (VTE), but established genetic risk factors are present in only half of VTE patients. AIM: To identify genetic risk factors in two large families with unexplained hereditary VTE. METHODS: We performed whole exome sequencing in 10 affected relatives of two unrelated families with an unexplained tendency for VTE. We prioritized variants shared by all affected relatives from both families, and evaluated these in the remaining affected and unaffected individuals...
2017: PloS One
https://www.readbyqxmd.com/read/29114197/low-levels-of-vitamin-d-an-emerging-risk-for-cardiovascular-diseases-a-review
#15
REVIEW
Farrukh Majeed
Sunlight is regarded among greatest gifts that are presented in abundance to the human beings from the God. Sunlight is also a rich source of Vitamin D (Vit D) that prevents us from numerous ailments such as autoimmune disorders, various types of cancer, and the above all cardiovascular diseases (CVD). Evident from recent research that Vit D deficiency may be the cause for hypertension, cardiac autonomic imbalance, vascular endothelial dysfunction, metabolic syndrome, and even diabetes. Concurrently, many studies present research outcomes that are contradictory to earlier results and also raised a concern not for general public but also among their treating physicians...
November 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29112689/hiv-prevalence-and-behavioral-and-psychosocial-factors-among-transgender-women-and-cisgender-men-who-have-sex-with-men-in-8-african-countries-a-cross-sectional-analysis
#16
Tonia Poteat, Benjamin Ackerman, Daouda Diouf, Nuha Ceesay, Tampose Mothopeng, Ky-Zerbo Odette, Seni Kouanda, Henri Gautier Ouedraogo, Anato Simplice, Abo Kouame, Zandile Mnisi, Gift Trapence, L Leigh Ann van der Merwe, Vicente Jumbe, Stefan Baral
INTRODUCTION: Sub-Saharan Africa bears more than two-thirds of the worldwide burden of HIV; however, data among transgender women from the region are sparse. Transgender women across the world face significant vulnerability to HIV. This analysis aimed to assess HIV prevalence as well as psychosocial and behavioral drivers of HIV infection among transgender women compared with cisgender (non-transgender) men who have sex with men (cis-MSM) in 8 sub-Saharan African countries. METHODS AND FINDINGS: Respondent-driven sampling targeted cis-MSM for enrollment...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29110788/worldwide-trends-in-heart-and-lung-transplantation-guarding-the-most-precious-gift-ever
#17
REVIEW
Vera von Dossow, Joseph Costa, Frank D'Ovidio, Nandor Marczin
Transplantation is sadly a therapy to die for. The survival of a recipient with end-stage heart or lung disease requires the demise of a human being through brain death or cessation of circulation, with the noblest final act of offering one's organs to another. However, transplantation is constrained by severe hemodynamic, regulatory, inflammatory, and metabolic stresses in the donor, rendering the majority of offered organs unsuitable for transplantation. Coupled with our inability to acquire exact molecular and cellular information and missed opportunities for effectively modulating deteriorations of donors and allografts, anesthesia and critical care contributes to ongoing organ shortages...
June 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29109241/optogenetic-activation-of-the-fruitless-labeled-circuitry-in-drosophila-subobscura-males-induces-mating-motor-acts
#18
Ryoya Tanaka, Tomohiro Higuchi, Soh Kohatsu, Kosei Sato, Daisuke Yamamoto
It remains an enigma how the nervous system of different animal species produces different behaviors. We studied the neural circuitry for mating behavior in Drosophila subobscura, a species that displays unique courtship actions not shared by other members of the genera including the genetic model D. melanogaster, in which the core courtship circuitry has been identified. We disrupted the D. subobscurafruitless (fru) gene, a master regulator for the courtship circuitry formation in D. melanogaster, resulting in complete loss of mating behavior...
November 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29108589/the-lasting-effect-of-intergenerational-wealth-transfers-human-capital-family-formation-and-wealth
#19
Richard A Benton, Lisa A Keister
Recent evidence indicates that inheritances and other intergenerational wealth transfers have only a limited effect on wealth inequality and the intergenerational transmission of financial well-being. In this study, we explore the role that human capital and family formation play in mediating the relationship between receiving a transfer and building wealth. We examine how educational attainment and family formation determine whether or not households are able to convert inheritances into greater assets, facilitating improved wealth accumulation...
November 2017: Social Science Research
https://www.readbyqxmd.com/read/29106732/a-systematic-review-of-incentives-in-blood-donation
#20
Kathleen Chell, Tanya E Davison, Barbara Masser, Kyle Jensen
BACKGROUND: Incentives are often used to enhance the effectiveness of recruitment and retention campaigns targeting blood donors. However, the degree to which incentives succeed in attracting and facilitating repeat donation is unclear. A systematic literature review, following PRISMA guidelines, investigated the existing empirical evidence regarding the use of monetary and nonmonetary incentives within blood donation. STUDY DESIGN AND METHODS: A comprehensive search of relevant databases identified a total of 71 papers for inclusion in the review for defining and operationalizing incentives (Objective 1), of which nine papers empirically investigated attitudes toward incentives (Objective 2), 31 papers investigated the impact on blood donation behavior (Objective 3), and eight papers investigated the impact on blood safety (Objective 4)...
November 6, 2017: Transfusion
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