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https://www.readbyqxmd.com/read/28655118/giant-juvenile-fibroadenoma-in-a-9-year-old-a-case-presentation-and-review-of-the-current-literature
#1
Michalina Kupsik, Brian Yep, Suela Sulo, Heidi Memmel
Juvenile fibroadenoma is the most common breast mass in adolescents accounting for 0.5-4% of all cases of fibroadenomas. Giant fibroadenomas are well-circumscribed, firm breast masses characterized by proliferation of epithelial and connective tissue. They are defined as being larger than 5 cm or weighing more than 500 g. The peak age has been reported between the ages of 17 and 20, with less than 5% of these in patients less than 18-years-old.We present a 9-year-old, pre-menstrual, Nigerian female with no known family history of breast masses or cancers who developed spontaneous giant fibroadenoma measuring approximately 13  cm × 13 cm...
June 23, 2017: Breast Disease
https://www.readbyqxmd.com/read/28654856/evaluation-of-a-self-regulation-based-psycho-educational-pilot-intervention-targeting-children-and-adolescents-with-epilepsy-in-greece
#2
Ioanna Rizou, Veronique De Gucht, Antigone Papavasiliou, Stan Maes
PURPOSE: The purpose of this study is to describe the development and initial evaluation of a minimal structured psycho-educational intervention for children and adolescents with epilepsy. The intervention aimed at increasing the understanding and personal control (self-management) of epilepsy, and at reducing psychological distress, sleep problems and somatic complaints. METHOD: Twelve patients participated in our intervention and another 12, matched on age and gender, served as the control group...
June 21, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28654499/physical-exercise-and-physical-activity-for-children-and-adolescents-with-juvenile-idiopathic-arthritis-a-literature-review
#3
Hilenia Catania, Viola Fortini, Rolando Cimaz
PURPOSE: This is a review of studies that investigate the efficacy of exercise therapy and physical activity for children with juvenile idiopathic arthritis since the 2008 Cochrane Review. METHOD: Studies were identified that investigated the use of physical activity and exercise therapy in the treatment of children and adolescents with juvenile idiopathic arthritis, excluding the Cochrane Review. Two reviewers individually analyzed the results of the search to determine the eligibility of studies...
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654442/low-intensity-pulsed-ultrasound-therapy-for-a-symptomatic-persistent-olecranon-physis-in-an-adolescent-baseball-pitcher
#4
Kenneth Botwin, Thurston McMillen, Ariel Botwin
A 15-year-old competitive right-handed high school baseball pitcher experienced an acute onset of right elbow pain when throwing. He initially treated it conservatively with rest alone for 3 months, but on return to throwing, he was still experiencing pain. Radiographs revealed that he had a persistent olecranon physis. He proceeded with a trial of low-intensity pulsed ultrasound therapy and attained radiographic evidence of bony union at 7 months postinjury, thus avoiding surgical intervention. He returned to pitching competitively 9 months after injury without elbow pain...
June 22, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28653465/introduction-to-anomalous-aortic-origin-of-a-coronary-artery
#5
Julie A Brothers
Anomalous aortic origin of a coronary artery (AAOCA) occurs when both coronary arteries arise from the same aortic sinus from a single ostium or two separate ostia. While most coronary anomalies are benign, the two most common subtypes that predispose to sudden cardiac death in the young are interarterial anomalous right coronary artery and interarterial anomalous left coronary artery. Practitioners face many challenges with AAOCA. Diagnosing patients may be difficult because children and adolescents are often asymptomatic and first presentation may be sudden death or sudden cardiac arrest...
June 27, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28652862/dysfunctional-maltreatment-related-cognitions-in-children-and-adolescents
#6
Anke de Haan, Helene G Ganser, Annika Münzer, Andreas Witt, Lutz Goldbeck
BACKGROUND: Dysfunctional trauma-related cognitions correlate highly with chronic stress. Studies on maltreatment-related cognitions and their predictors in children and adolescents are rare. METHODS: The study sample consisted of 231 children aged 8-17 years who had experienced maltreatment including domestic violence, emotional abuse, neglect, physical, and sexual abuse. Using multiple linear regression analysis, gender, age, index-event, multi-type maltreatment, out-of-home-care, and migration background were investigated as possible predictors of dysfunctional maltreatment-related cognitions...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28652828/prevention-treatment-and-rehabilitation-of-anterior-cruciate-ligament-injuries-in-children
#7
REVIEW
Pamela J Lang, Dai Sugimoto, Lyle J Micheli
As more children and adolescents participate in competitive organized sports, there has been an increase in the reported incidence of anterior cruciate ligament (ACL) injuries in these age groups. ACL injuries in skeletally immature athletes present a challenge, as reconstruction must preserve the physis of the distal femur and of the proximal tibia to avoid growth disturbances. Historically, a skeletally immature athlete with an ACL injury was treated with a brace and activity modification until skeletal maturity, with ACL reconstruction being performed at that time in the "non-copers" who experienced instability...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28652498/prevalence-and-correlates-of-psychological-distress-in-adolescent-students-from-india
#8
T S Jaisoorya, D Geetha, K V Beena, M Beena, K Ellangovan, K Thennarasu
OBJECTIVE: There are limited data on the prevalence and correlates of psychological distress among adolescents in India. This study assessed psychological distress among adolescents who attended school in Kerala, India. METHODS: A total of 7560 students from 73 schools, aged 12 to 19 years completed a self-administered questionnaire that included Kessler Psychological Distress Scale and other standardised instruments to assess various domains. RESULTS: Mild psychological distress was reported by 10...
June 2017: East Asian Archives of Psychiatry: Official Journal of the Hong Kong College of Psychiatrists
https://www.readbyqxmd.com/read/28652281/implementation-of-a-school-based-educational-program-to-increase-breast-cancer-awareness-and-promote-intergenerational-transmission-of-knowledge-in-a-rural-mexican-community
#9
Enrique Soto-Perez-de-Celis, David D Smith, Maria Patricia Rojo-Castillo, Arti Hurria, Alba Milena Pavas-Vivas, Rina Gitler-Weingarten, Alejandro Mohar, Yanin Chavarri-Guerra
BACKGROUND: Rural women have limited access to breast cancer education, which partially contributes to late diagnosis and treatment. In this pilot study, we tested the feasibility of implementing a school-based breast cancer educational program for adolescents in a rural Mexican community. We hypothesized that the adolescents' knowledge on breast cancer would increase as a result of the program, and that there would be intergenerational transmission of that knowledge to their older female relatives...
June 26, 2017: Oncologist
https://www.readbyqxmd.com/read/28652205/opioid-analgesics-administered-for-pain-on-the-inpatient-pediatric-setting
#10
Gary A Walco, Nancy Gove, Jennifer Phillips, Steven J Weisman
This study aimed to describe utilization of opioid medications among infants, children, and adolescents on the inpatient setting. These data are needed to guide clinical trials and improve research methodologies, as well as to inform more about possible sources of opioid misuse in the United States. A retrospective chart review was conducted covering a span of one year, with a special focus on the prescription of opioids for long-term treatment of chronic pain. Opioid medications were prescribed for less than 5 days in the overwhelming majority (75%) of patients...
June 23, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28651213/reward-related-frontostriatal-activity-and-smoking-behavior-among-adolescents-in-treatment-for-smoking-cessation
#11
Kathleen A Garrison, Sarah W Yip, Iris M Balodis, Kathleen M Carroll, Marc N Potenza, Suchitra Krishnan-Sarin
BACKGROUND: Tobacco use is often initiated during adolescence and continued into adulthood despite desires to quit. A better understanding of the neural correlates of abstinence from smoking in adolescents may inform more effective smoking cessation interventions. Neural reward systems are implicated in tobacco use disorder, and adolescent smokers have shown reduced reward-related ventral striatal activation related to increased smoking. METHODS: The current study evaluated nondrug reward anticipation in adolescent smokers using a monetary incentive delay task in fMRI pre- and post- smoking cessation treatment (n=14)...
June 3, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28649417/pilot-study-of-a-randomized-trial-to-evaluate-a-web-based-intervention-targeting-adolescents-presenting-to-the-emergency-department-with-acute-asthma
#12
Christine L M Joseph, Prashant Mahajan, Stephanie Stokes-Buzzelli, Dayna A Johnson, Elizabeth Duffy, Renee Williams, Talan Zhang, Dennis R Ownby, Shannon Considine, Mei Lu
BACKGROUND: Low-income African-American adolescents use preventive medical services less frequently than their White counterparts, indicating a need for effective interventions targeting this group. Puff City is a Web-based, asthma management program for urban adolescents that has been evaluated in high school settings with promising results. The objective of this pilot was to assess the feasibility of initiating Puff City (treatment) in an emergency department setting, thereby informing the conduct of an individual randomized trial to evaluate its effectiveness compared to a generic, Web-based program (control) in preventing subsequent emergency department (ED) visits...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28648163/-self-injury-converting-emotional-distress-into-physical-pain
#13
Bo Møhl, Lotte Rubæk
Self-inflicted pain by cutting, hitting or burning oneself has become a common way to regulate emotions and to serve as coping strategy. 21.5-32% of adolescents in non-clinical populations have a history of non-suicidal self-injury. Non-suicidal self-injury has a momentarily relieving effect and is an important predictor of suicidal behaviour; even superficial self-injury should be taken seriously. There is an urgent need for organized treatment programmes for young people who self-harm.
June 26, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28647950/turner-syndrome-care-of-the-patient-birth-to-late-adolescence
#14
Denise Gruccio Paolucci, Vaneeta Bamba
Turner syndrome (TS) is a genetic condition occurring in females resulting from the loss of part or all of one of the X chromosomes. The two hallmark features of Turner syndrome include short stature and primary ovarian insufficiency. In addition, Turner syndrome can involve multiple healthcare issues including cardiac and renal anomalies, autoimmune disorders, hearing loss, ophthalmologic issues, bone anomalies, dermatologic issues and psychosocial and educational concerns. The presenting signs of Turner syndrome can vary markedly, leading to delayed or even missed diagnosis...
June 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28647791/premonitory-symptoms-of-migraine-in-childhood-and-adolescence
#15
REVIEW
N Karsan, P Prabhakar, P J Goadsby
PURPOSE OF REVIEW: Premonitory symptoms in migraine; symptoms occurring before the onset of migraine pain or aura, are an increasingly recognised area of interest within headache research. It has been recently documented in the literature that these symptoms also occur in children and adolescents, with a comparable phenotype to adults. This review discusses the wide presentation of premonitory symptoms in migraine in children and adolescents, and the importance of understanding how these early symptoms are mediated in order to ensure that targeted abortive therapies are developed in the future...
July 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28647564/effects-of-chronic-forced-swim-stress-on-behavioral-properties-in-rats-with-neonatal-repeated-mk-801-treatment
#16
Kouichi Kawabe
The two-hit hypothesis has been used to explain the onset mechanism of schizophrenia. It assumes that predisposition to schizophrenia is originally attributed to vulnerability in the brain which stems from genetic or early developmental factors, and that onset is triggered by exposure to later detrimental factors such as stress in adolescence or adulthood. Based on this hypothesis, the present study examined whether rats that had received neonatal repeated treatment with an N-methyl-d-aspartate (NMDA) receptor antagonist (MK-801), an animal model of schizophrenia, were vulnerable to chronic stress...
June 21, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28647011/brain-structural-signatures-of-adolescent-depressive-symptom-trajectories-a-longitudinal-magnetic-resonance-imaging-study
#17
Lianne Schmaal, Murat Yücel, Rachel Ellis, Nandita Vijayakumar, Julian G Simmons, Nicholas B Allen, Sarah Whittle
OBJECTIVE: Most evidence for structural brain abnormalities associated with adolescent depression is based on cross-sectional study designs that do not take into account the dynamic course of depressive symptoms and brain maturation across adolescence. In this study, a longitudinal design was used to investigate the association between different trajectories of depressive symptoms and longitudinal changes in brain structure throughout adolescence. METHOD: One hundred forty-nine adolescents were assessed on depressive symptoms and underwent structural magnetic resonance imaging at 12 years of age and were followed up multiple times until 19 years...
July 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28647010/social-skills-training-for-children-and-adolescents-with-autism-spectrum-disorder-a-randomized-controlled-trial
#18
Nora Choque Olsson, Oskar Flygare, Christina Coco, Anders Görling, Anna Råde, Qi Chen, Katarina Lindstedt, Steve Berggren, Eva Serlachius, Ulf Jonsson, Kristiina Tammimies, Lars Kjellin, Sven Bölte
OBJECTIVE: Social skills group training (SSGT) for children and adolescents with autism spectrum disorder (ASD) is widely applied, but effectiveness in real-world practice has not yet been properly evaluated. This study sought to bridge this gap. METHOD: This 12-week pragmatic randomized controlled trial of SSGT compared to standard care alone was conducted at 13 child and adolescent psychiatry outpatient units in Sweden. Twelve sessions of manualized SSGT ("KONTAKT") were delivered by regular clinical staff...
July 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28646962/the-long-shadow-of-lemierre-s-syndrome
#19
Joshua Osowicki, Sarah Kapur, Linny Kimly Phuong, Simon Dobson
Lemierre's syndrome is a rare and feared complication of pharyngitis, occurring most commonly in adolescents and young adults. It is typically defined by the constellation of septic internal jugular vein thrombophlebitis, pulmonary and other septic emboli, and sterilesite infection by Fusobacterium necrophorum. The rarity and severity of Lemierre's syndrome has made it an attractive subject for case reports but there is a paucity of evidence to inform areas of persistent uncertainty. In recent years, heightened attention and controversy has focused upon speculation that a purported rise in the incidence of Lemierre's syndrome is due to reduced antibiotic prescribing for respiratory tract infections, that F...
June 2017: Journal of Infection
https://www.readbyqxmd.com/read/28646426/eftrenonacog-alfa-a-review-in-haemophilia-b
#20
Sheridan M Hoy
Eftrenonacog alfa (Alprolix™) is a recombinant fusion protein comprising human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 (i.e. rFIXFc). The presence of the Fc domain extends the terminal half-life (t½) of rFIXFc, permitting prolonged treatment intervals. rFIXFc is available for intravenous use for the prophylaxis and treatment of bleeding in patients with haemophilia B. In two multinational, phase III studies in previously treated children, adolescents and adults with severe haemophilia B, rFIXFc prophylaxis resulted in low median annualized bleeding rates (ABRs), and was associated with reductions in median weekly factor consumption and dosing frequency compared with pre-study FIX regimens...
June 23, 2017: Drugs
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