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https://www.readbyqxmd.com/read/28534925/osmotin-loaded-magnetic-nanoparticles-with-electromagnetic-guidance-for-the-treatment-of-alzheimer-s-disease
#1
Faiz Ul Amin, Ali Kafash Hoshiar, Ton Duc Do, Yeongil Noh, Shahid Ali Shah, Muhammad Sohail Khan, Jungwon Yoon, Myeong Ok Kim
Alzheimer's disease (AD) is the most prevalent age-related neurodegenerative disease, pathologically characterized by the accumulation of aggregated amyloid beta (Aβ) in the brain. Here, we describe for the first time the development of a new, pioneering nanotechnology-based drug delivery approach for potential therapies for neurodegenerative diseases, particularly AD. We demonstrated the delivery of fluorescent carboxyl magnetic Nile Red particles (FMNPs) to the brains of normal mice using a functionalized magnetic field (FMF) composed of positive- and negative-pulsed magnetic fields generated by electromagnetic coils...
May 23, 2017: Nanoscale
https://www.readbyqxmd.com/read/28532405/red-meat-and-chicken-consumption-and-its-association-with-high-blood-pressure-and-obesity-in-south-korean-children-and-adolescents-a-cross-sectional-analysis-of-kshes-2011-2015
#2
Geum Hee Kim, Sang Won Shin, Juneyoung Lee, Jun Hyun Hwang, Soon-Woo Park, Jin Soo Moon, Hyun Jung Kim, Hyeong Sik Ahn
BACKGROUND: The impact of meat consumption on high blood pressure (HBP) and obesity in children and adolescents is a subject of debate. The aim of this study was thus to evaluate the association between meat consumption and both HBP and obesity in this group. METHODS: We performed a cross-sectional analysis using nationally representative samples of children and adolescents aged 9, 12, and 15 years old (n = 136,739) who were included in the Korea School Health Examination Survey (KSHES) for the 2011-2015 period...
May 22, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28528142/per-and-polyfluoroalkyl-substances-pfas-in-american-red-cross-adult-blood-donors-2000-2015
#3
Geary W Olsen, David C Mair, Cleston C Lange, Laura M Harrington, Timothy R Church, Corinne L Goldberg, Ross M Herron, Hank Hanna, John B Nobiletti, Jorge A Rios, William K Reagen, Carol A Ley
In 2015, thirteen per- and polyfluoroalkyl substances (PFAS), including perfluorohexanesulfonate (PFHxS), perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), perfluorononanoate (PFNA), and perfluorodecanoate (PFDA) were analyzed in human plasma that was collected from a total of 616 American Red Cross male and female blood donors (ages 20-69) at 6 regional blood collection centers. Plasma samples were analyzed using a validated solvent precipitation-isotope dilution direction-liquid chromatography tandem mass spectrometry method...
May 17, 2017: Environmental Research
https://www.readbyqxmd.com/read/28528104/effect-of-egg-albumin-fining-progressive-clarification-and-cross-flow-microfiltration-on-the-polysaccharide-and-proanthocyanidin-composition-of-red-varietal-wines
#4
Leticia Martínez-Lapuente, Zenaida Guadalupe, Belén Ayestarán
The effect of egg albumin fining, progressive clarification and cross-flow microfiltration on the polysaccharide and proanthocyanidin composition of four red varietal wines was studied in this work. Discriminant analyses were applied to achieve a possible differentiation of the wines according to treatment or grape variety. Egg albumin fining did no produce a significant decrease in the content of wine polysaccharides. Progressive clarification caused a significant reduction of mannoproteins, homogalacturonans and polysaccharides rich in arabinose and galactose in Graciano wines...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28526635/arsenic-exposures-alter-clinical-indicators-of-anemia-in-a-male-population-of-smokers-and-non-smokers-in-bangladesh
#5
Faruque Parvez, Sebastian Medina, Regina Santella, Tariqul Islam, Fredine T Lauer, Nur Alam, Mahbubul Eunus, Mizanour Rahman, Pam Factor-Litvak, Habib Ahsan, Joseph Graziano, Ke Jian Liu, Scott W Burchiel
Drinking water arsenic (WAs) exposure has been linked to a number of detrimental health outcomes including anemia, primarily among pregnant women. Little is known about the effects of arsenic (As) on hematological disorders among men. We have examined the role of As exposure on hematological indicators of anemia in a group of men exposed to a wide range of As in their drinking water. We conducted a cross-sectional investigation among 119 healthy men in the Health Effects of As Longitudinal Study (HEALS) cohort, in rural Bangladesh...
May 16, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28523169/risk-factors-for-continuous-renal-replacement-therapy-after-surgical-repair-of-type-a-aortic-dissection
#6
Hai-Bo Wu, Wei-Guo Ma, Hong-Lei Zhao, Jun Zheng, Jian-Rong Li, Ou Liu, Li-Zhong Sun
BACKGROUND: To identify the risk factors for continuous renal replacement therapy (CRRT) following surgical repair of type A aortic dissection (TAAD) using the total arch replacement and frozen elephant trunk (TAR + FET) technique. METHODS: The study included 330 patients with TAAD repaired using TAR + FET between January 2014 and April 2015. Mean age was 47.1±10.2 years (range, 18-73 years) and 242 were male (73.3%). Univariate and multivariate analyses were used to identify the risk factors for CRRT...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28514984/alternate-mediterranean-diet-score-is-positively-associated-with-skeletal-muscle-mass-index-in-middle-aged-adults
#7
Hui-Yuan Tian, Rui Qiu, Li-Peng Jing, Zhan-Yong Chen, Geng-Dong Chen, Yu-Ming Chen
Researches have suggested Mediterranean diet might lower the risk of chronic diseases, but data on skeletal muscle mass (SMM) are limited. This community-based cross-sectional study examined the association between the alternate Mediterranean diet score (aMDS) and SMM in 2230 females and 1059 males aged 40-75 years in Guangzhou, China. General information and habitual dietary information were assessed in face-to-face interviews conducted during 2008-2010 and 3 years later. The aMDS was calculated by summing the dichotomous points for the items of higher intakes of whole grain, vegetables, fruits, legumes, nuts, fish and ratio of MUFA:SFA, lower red meat and moderate ethanol consumption...
May 18, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28513134/silicon-quantum-dots-in-dielectric-scattering-media-broadband-enhancement-of-effective-absorption-cross-section-by-light-trapping
#8
Hiroshi Sugimoto, Yusuke Ozaki, Minoru Fujii
We report strong enhancements of the effective absorption cross section and photoluminescence (PL) intensity of silicon quantum dots (Si QDs) with 2.8-6.8 nm in diameter in a highly scattering dielectric medium. The scattering medium is a polymer thin film with submicrometer size pores inside, supporting the resonant cavity modes in the visible range. By the scattering associated with the cavity modes, efficient light trapping into a polymer film with ∼1 μm in thickness is achieved, which leads to 30-40 times enhancement of the effective absorption cross section of embedded Si QDs in a green-red wavelength range...
May 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28511389/variability-of-iron-load-in-patients-of-sickle-cell-anaemia-hbss-a-study-from-eastern-india
#9
Pranati Mohanty, Rabindra Kumar Jena, Sudha Sethy
INTRODUCTION: Sickle Cell Anaemia (SCA) is one of the commonest haemoglobinopathies due to a point mutation (A→T) of the β-globin gene. Out of five haplotypes, the Arab-Indian haplotype present in India is one of the least severe phenotype and least studied also. It is characterized by lifelong haemolytic anaemia requiring red cell transfusion leading to iron overload. In contrast, there is very high incidence of deficiency of iron, folic acid and vitamin B12. AIM: Our objective was to access the Iron status of SCA patients and to find its correlation with various parameters like red cell transfusion, haemolysis and serum hepcidin...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508550/photoluminescent-peptide-based-nanostructures-as-fret-donor-for-fluorophore-dye
#10
Antonella Accardo, Giancarlo Morelli, Carlo Diaferia, Luigi Vitagliano, Cinzia Giannini, Teresa Sibillano, Valentina Roviello
A great interest has been recently generated by the discovery that peptide-based nanostructures (NSs) endowed with cross-β structure may show interesting photoluminescent (PL) properties. In this scenario, we have shown that NSs formed by PEGylated hexaphenylalanine (PEG8-F6) are able to emit at 460 nm when excited at 370 or at 410 nm. Here, we explored the possibility to transfer the fluorescence of these PEG8-F6-based NSs by Foster Resonance Electron Transfer (FRET) phenomenon to a fluorescent dye. To achieve this aim, we encapsulated in these NSs the 4-Chloro-7-nitrobenzofurazan (NBD) dye...
May 16, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28508000/knowledge-and-attitude-of-iranian-red-crescent-society-volunteers-in-dealing-with-chemical-attacks
#11
Maryam Nadjafi, Siavash Hamzeh Pour
OBJECTIVE: To evaluate the knowledge, attitude, and preparedness of Mahabad Red Crescent Society volunteers in dealing with chemical attacks. METHODS: This prospective cross-sectional study was conducted on 120 Red Crescent Society volunteers in Mahabad City, Iran, during 2014-2015.The knowledge of the volunteers was evaluated and rated using a questionnaire as poor, moderate, and good. Also, the attitude of the volunteers towards the chemical attacks and their preparedness were rated as appropriate and inappropriate using a questionnaire...
April 2017: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/28507611/the-impact-of-extended-typing-on-red-blood-cell-alloimmunization-in-transfused-patients
#12
Tatjana Makarovska-Bojadzieva, Emilija Velkova, Milenka Blagoevska
BACKGROUND: Red blood cell (RBC) alloimmunization is still an actual problem in our transfusion practice. In 2011, in addition to the regular ABO/D blood group typing, phenotyping for Rh (C, c, E, e) and Kell antigens was introduced for blood donors and patients undergoing blood transfusion. Our aim was to evaluate the impact of the extended RBC typing and donor/recipient matching on the incidence of RBC alloimmunization. METHODS: A retrospective comparative study was conducted by reviewing RBC request records for about 36,000 patients transfused with RBC in the period from 2013 to 2015 in comparison to the similar study conducted on 47,000 transfused patients in the period from 2005 to 2008...
April 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28507571/transcatheter-paravalvular-leak-closure-and-hemolysis-a-prospective-registry
#13
Grzegorz Smolka, Piotr Pysz, Andrzej Ochała, Michał Kozłowski, Wojciech Zasada, Zofia Parma, Michał Tendera, Wojciech Wojakowski
INTRODUCTION: Paravalvular leak (PVL) related to a surgical prosthetic valve may be associated with clinically significant hemolysis. The influence of transcatheter PVL closure (TPVLC) on hemolysis remains uncertain. MATERIAL AND METHODS: The prospective registry included patients undergoing TPVLC due to PVL-related heart failure and/or hemolysis. Procedural data, laboratory markers of hemolysis and heart failure status were recorded at baseline, discharge and at 1- and 6-month follow-up...
April 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28503294/a-survey-of-free-ranging-deer-in-ireland-for-serological-evidence-of-exposure-to-bovine-viral-diarrhoea-virus-bovine-herpes-virus-1-bluetongue-virus-and-schmallenberg-virus
#14
David A Graham, Clare Gallagher, Ruth F Carden, Jose-Maria Lozano, John Moriarty, Ronan O'Neill
BACKGROUND: Deer are an important wildlife species in both the Republic of Ireland and Northern Ireland having colonised most regions across the island of Ireland. In comparison to cattle and sheep which represent the main farmed ruminant species on the island, there is a lack of data concerning their exposure, as measured by the presence of antibodies, to important viral pathogens of ruminants. A study was therefore undertaken to investigate the seroprevalence of wild deer to four viruses, namely bovine viral diarrhoea virus (BVDV), bovine herpesvirus-1 (BoHV-1), Schmallenberg virus (SBV) and bluetongue virus (BTV)...
2017: Irish Veterinary Journal
https://www.readbyqxmd.com/read/28501359/the-ebola-epidemic-in-liberia-and-managing-the-dead-a-future-role-for-humanitarian-forensic-action
#15
Stephen Cordner, Heinrich Bouwer, Morris Tidball-Binz
With some of their economies, communities and health systems weakened by decades of war and poor governance, it was no accident that an epidemic of Ebola virus disease broke out in west Africa. Being spread in part by contact with body fluids of those who had died from the disease, funerary rites and the way dead bodies were managed were important modes of transmission. The Liberian Red Cross, supported by the International Federation of Red Cross and Red Crescent Societies and the International Committee of the Red Cross, undertook the challenging task of managing the dead bodies in Monrovia during the epidemic...
April 25, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28500964/dietary-linseed-oil-supplemented-with-organic-selenium-improved-the-fatty-acid-nutritional-profile-muscular-selenium-deposition-water-retention-and-tenderness-of-fresh-pork
#16
Jiang Jiang, Xinyue Tang, Yan Xue, Gang Lin, Youling L Xiong
Cross-bred pigs were fed a control diet (with 0.3ppm sodium selenite and 1.5% soybean oil) or organic selenium diets (0.3ppm Se-Yeast with 1.5% soybean or linseed oil) to investigate nutrient supplement effects on meat quality and oxidative stability. The organic selenium diets increased muscular selenium content up to 54%, and linseed oil increased n-3 fatty acids two-fold while lowering the n-6/n-3 fatty acid ratio from 13.9 to 5.9 over the selenite control diet (P<0.05). Organic selenium yeast treatments with linseed oil reduced pork drip loss by 58-74% when compared with diets with soybean oil...
April 6, 2017: Meat Science
https://www.readbyqxmd.com/read/28498177/effectiveness-of-topical-skin-products-in-the-treatment-and-prevention-of-incontinence-associated-dermatitis-a-systematic-review
#17
Priscilla Pather, Sonia Hines, Kate Kynoch, Fiona Coyer
BACKGROUND: Incontinence-associated dermatitis (IAD) is inflammation of the skin resulting from repeated contact with urine and/or feces. It causes pain, redness, swelling and excoriation, and may lead to complications such as fungal skin infections and pressure injuries. It is important to prevent and treat IAD to avoid complications and improve patient outcomes. A number of products are available for protecting skin, but evidence on their effectiveness is limited. OBJECTIVES: The current review aimed to establish the effectiveness of topical skin products in reducing the occurrence and/or severity of IAD...
May 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28497572/relationship-between-red-blood-cell-distribution-width-bilirubin-and-clinical-characteristics-of-patients-with-gastric-cancer
#18
T-T Wei, L-L Wang, J-R Yin, Y-T Liu, B-D Qin, J-Y Li, X Yin, L Zhou, R-Q Zhong
INTRODUCTION: Red blood cell distribution width (RDW) and bilirubin have been proved to be prognostic factors for various types of cancer. However, their prognostic value in patients with gastric cancer (GC) remains largely unknown. METHODS: To verify whether RDW and bilirubin are prognostic factors for patients with GC, we performed a cross-sectional study to analyze the relationship between RDW, bilirubin, and the clinical characteristics of patients with GC. Medical records of all newly diagnosed and pathologically proved patients with GC admitted to Changzheng Hospital between January 2016 and July 2016 were retrospectively reviewed...
May 12, 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28492620/novel-red-phosphors-kbaeu-xo4-3-x-mo-w-show-high-color-purity-and-high-thermostability-from-a-disordered-chained-structure
#19
G Q Wang, X H Gong, Y J Chen, J H Huang, Y F Lin, Z D Luo, Y D Huang
Two novel red phosphors KBaEu(XO4)3 (X = Mo, W) have been synthesized by high-temperature solid-state reactions and the crystal structures were determined for the first time. Single-crystal X-ray diffraction data reveal that their space groups are C2/c. The crystalline structure is constituted of K/BaO8 distorted square antiprisms and distorted EuO8 polyhedra which form chains lying along the c-axis and two kinds of distorted XO4 tetrahedra. This high disorder of K/Ba which might lower the crystal field symmetry around Eu(3+) results in the high purity of red emission around 615 nm originating from (5)D0 → (7)F2 transition under near-ultraviolet (NUV) excitation...
May 11, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28491075/saturation-mapping-of-a-major-effect-qtl-for-stripe-rust-resistance-on-wheat-chromosome-2b-in-cultivar-napo-63-using-snp-genotyping-arrays
#20
Jianhui Wu, Qilin Wang, Shengjie Liu, Shuo Huang, Jingmei Mu, Qingdong Zeng, Lili Huang, Dejun Han, Zhensheng Kang
Stripe rust or yellow rust (YR), caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most important diseases of wheat (Triticum aestivum L.). Widespread deployment of resistant cultivars is the best means of achieving durable disease control. The red grain, spring wheat cultivar Napo 63 produced by CIMMYT in the 1960s shows a high level of adult-plant resistance to stripe rust in the field. To elucidate the genetic basis of resistance in this cultivar we evaluated 224 F2:3 lines and 175 F2:6 recombinant inbred lines (RILs) derived from a cross between Napo 63 and the Pst-susceptible line Avocet S...
2017: Frontiers in Plant Science
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