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https://www.readbyqxmd.com/read/27909552/vonoprazan-20-mg-vs-lansoprazole-30-mg-for-endoscopic-submucosal-dissection-induced-gastric-ulcers
#1
Kazuya Takahashi, Yuichi Sato, Junji Kohisa, Jun Watanabe, Hiroki Sato, Kenichi Mizuno, Satoru Hashimoto, Shuji Terai
AIM: To compare the healing effects of vonoprazan and lansoprazole on gastric ulcers induced by endoscopic submucosal dissection (ESD). METHODS: Data were obtained from a total of 26 patients. Fourteen patients were randomized to the vonoprazan group and 12 were randomized to the lansoprazole group. Patients were administered either 20 mg vonoprazan or 30 mg lansoprazole per day after ESD. Endoscopic images just after ESD, on day 8, and on day 28 were used for the evaluation of the shrinking rate of ESD ulcers...
November 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27905029/risk-factors-and-management-for-gastric-stenosis-after-endoscopic-submucosal-dissection-for-gastric-epithelial-neoplasm
#2
Tetsuya Sumiyoshi, Hitoshi Kondo, Takeyoshi Minagawa, Ryoji Fujii, Kaho Sakata, Kenichi Inaba, Tomohiro Kimura, Hideyuki Ihara, Naohito Yoshizaki, Michiaki Hirayama, Yumiko Oyamada, Shunichi Okushiba
BACKGROUND: Only a few studies have reported treatment options for stenosis after endoscopic submucosal dissection (ESD) for gastric neoplasms. This study aimed to identify the risk factors for and evaluate the management of stenosis after ESD for gastric epithelial neoplasms in the cardia and antrum. METHODS: We retrospectively reviewed 1218 patients (1447 gastric epithelial neoplasms) who underwent ESD at Tonan Hospital from June 2004 to November 2015. Post-ESD stenosis was defined when a standard endoscope could not be passed through the site...
November 30, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/27900464/long-term-outcomes-of-colorectal-endoscopic-submucosal-dissection-in-elderly-patients
#3
Yoshifumi Takahashi, Ken-Ichi Mizuno, Kazuya Takahashi, Hiroki Sato, Satoru Hashimoto, Manabu Takeuchi, Masaaki Kobayashi, Junji Yokoyama, Yuichi Sato, Shuji Terai
BACKGROUND AND AIMS: The safety and efficacy of endoscopic submucosal dissection (ESD) in elderly patients remain unclear. The aim of this study is to clarify the short- and long-term outcomes of colorectal ESD in elderly patients. PATIENTS AND METHODS: A total of 482 consecutive patients with 501 colorectal lesions treated with ESD from February 2005 to December 2013 were retrospectively reviewed. Patients were divided into two groups: an elderly group (≥ 75 years of age) and a non-elderly group (< 75 years of age)...
November 30, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27899322/a-randomized-controlled-trial-of-prophylactic-antibiotics-in-the-prevention-of-electrocoagulation-syndrome-after-colorectal-endoscopic-submucosal-dissection
#4
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim, Hyun Kyun Ki
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is currently commonly performed, but colorectal ESD has a substantial risk of adverse events, including post-ESD electrocoagulation syndrome (PEECS). We investigated whether the use of prophylactic antibiotics can reduce the occurrence of PEECS. METHODS: Patients who underwent colorectal ESD were randomly assigned to 1 of 2 treatment regimens. Ampicillin/sulbactam mixed with normal saline solution was administered 1 hour before ESD in group I, and then additionally injected every 8 hours twice more...
November 26, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27898310/potential-human-exposure-to-halogenated-flame-retardants-in-elevated-surface-dust-and-floor-dust-in-an-academic-environment
#5
Jaime M Allgood, Tamara Jimah, Carolyn M McClaskey, Mark J La Guardia, Stephanie C Hammel, Maryam M Zeineddine, Ian W Tang, Miryha G Runnerstrom, Oladele A Ogunseitan
Most households and workplaces all over the world possess furnishings and electronics, all of which contain potentially toxic flame retardant chemicals to prevent fire hazards. Indoor dust is a recognized repository of these types of chemicals including polybrominated diphenyl ethers (PBDEs) and non-polybrominated diphenyl ethers (non-PBDEs). However, no previous U.S. studies have differentiated concentrations from elevated surface dust (ESD) and floor dust (FD) within and across microenvironments. We address this information gap by measuring twenty-two flame-retardant chemicals in dust on elevated surfaces (ESD; n=10) and floors (FD; n=10) from rooms on a California campus that contain various concentrations of electronic products...
November 26, 2016: Environmental Research
https://www.readbyqxmd.com/read/27893832/evolutionary-algorithm-for-rna-secondary-structure-prediction-based-on-simulated-shape-data
#6
Soheila Montaseri, Mohammad Ganjtabesh, Fatemeh Zare-Mirakabad
BACKGROUND: Non-coding RNAs perform a wide range of functions inside the living cells that are related to their structures. Several algorithms have been proposed to predict RNA secondary structure based on minimum free energy. Low prediction accuracy of these algorithms indicates that free energy alone is not sufficient to predict the functional secondary structure. Recently, the obtained information from the SHAPE experiment greatly improves the accuracy of RNA secondary structure prediction by adding this information to the thermodynamic free energy as pseudo-free energy...
2016: PloS One
https://www.readbyqxmd.com/read/27891047/endoscopic-submucosal-dissection-outcomes-for-gastroesophageal-tumors-in-low-volume-units-a-multicenter-survey
#7
Ahmad Najib Azmi, Christopher J L Khor, Khek-Yu Ho, Rapat Pittayanon, Rungsun Rerknimitr, Thawee Ratanachu-Ek, Doreen S C Koay, Jianyi Calvin Koh, Shiaw-Hooi Ho, Khean-Lee Goh, Sanjiv Mahadeva
Background and Aims. Endoscopic submucosal dissection (ESD) outcomes have traditionally been reported from high volume centers in East Asia. Data from low volume centers in other parts of Asia remain sparse. Methods. A retrospective survey with a structured questionnaire of 5 tertiary centers in 3 countries in South East Asia was conducted. Details of training and clinical outcomes of ESD cases, with follow-up data from these centers, were analyzed. Results. Seven endoscopists from the 5 centers performed a total of 35 cases of ESD in the upper gastrointestinal tract (UGIT) over a 6-year duration...
2016: Diagnostic and Therapeutic Endoscopy
https://www.readbyqxmd.com/read/27889547/clinical-outcomes-of-non-curative-endoscopic-submucosal-dissection-with-negative-resected-margins-r0-resection-for-gastric-cancer
#8
Yosuke Toya, Masaki Endo, Shotaro Nakamura, Risaburo Akasaka, Takashi Kosaka, Shunichi Yanai, Keisuke Kawasaki, Keisuke Koeda, Tamotsu Sugai, Takayuki Matsumoto
BACKGROUND AND AIMS: There has been little information about the long-term outcomes of patients with early gastric cancer (EGC) treated by non-curative endoscopic submucosal dissection (ESD) with negative resected margins (R0 resection). We aimed to compare clinical outcomes of non-curative ESD with R0 resection between patients who underwent additional gastrectomy and those who did not. METHODS: Among EGC patients treated by ESD from 2000 to 2015, 66 patients were treated by non-curative ESD with R0 resection...
November 23, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27875854/duodenal-endoscopic-submucosal-dissection-is-feasible-using-the-pocket-creation-method
#9
Yoshimasa Miura, Satoshi Shinozaki, Yoshikazu Hayashi, Hirotsugu Sakamoto, Alan Kawarai Lefor, Hironori Yamamoto
Background and study aims: Duodenal endoscopic submucosal dissection (ESD) requires sophisticated endoscopic techniques because of a high rate of perforation. We introduced the pocket-creation method (PCM) of duodenal ESD to overcome difficulties. The aim of this study was to evaluate the safety and usefulness of ESD using the PCM for superficial tumors of the duodenum. Patients and methods: We performed ESD of 17 non-ampullary duodenal lesions using the conventional method and of 28 lesions using the PCM from 2006 to 2015 and retrospectively reviewed the results, comparing the PCM and the conventional method...
November 22, 2016: Endoscopy
https://www.readbyqxmd.com/read/27871804/additional-surgical-resection-after-endoscopic-mucosal-dissection-for-early-gastric-cancer-a-medium-sized-hospital-s-experience
#10
Bunzo Nakata, Masashige Tendo, Masatsugu Okuyama, Kenichi Nakahara, Hirotaka Ishizu, Go Masuda, Tomohiro Lee, Takeshi Hori, Masahiko Ohsawa, Hiroshi Sato, Tetsuro Ishikawa
PURPOSE: In Japan, the majority of early gastric cancers (EGCs) are now treated with endoscopic submucosal dissection (ESD). Patients with non-curative lesions treated by ESD are advised to undergo additional surgical resection (ASR) based on guidelines from the Japan Gastroenterological Endoscopy Society (JGES) and Japanese Gastric Cancer Association (JGCA). However, many studies have demonstrated that residual cancer and lymph node metastasis are only rarely found in ASR specimens. Here we retrospectively analyzed the conditions that could enable the avoidance of unnecessary ASR...
November 15, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27868244/ddw-2016-review-advances-in-therapeutic-upper-gastrointestinal-endoscopy
#11
REVIEW
Shannon Melissa Chan, Baldwin Yeung, Philip Wai Yan Chiu
This editorial provides a review of the lectures and abstracts presented at Digestive Disease Week 2016 in San Diego on advances in therapeutic upper gastrointestinal procedures. There were a significant number of reports on expanded indications for endoscopic submucosal dissection (ESD) of early gastric cancers, advanced endoscopic techniques for resection including submucosal tunnel endoscopic resection (STER) and endoscopic full thickness resection (EFTR), per oral endoscopic myotomy (POEM), and novel endoscopic techniques including antireflux mucosectomy (ARMS) as well as endoscopic suturing...
November 21, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27862291/probe-based-confocal-laser-endomicroscopy-in-the-margin-delineation-of-early-gastric-cancer-for-endoscopic-submucosal-dissection
#12
Jun Chul Park, Yehyun Park, Hyun Ki Kim, Jeong-Hyeon Jo, Chan Hyuk Park, Eun Hye Kim, Da Hyun Jung, Hyunsoo Chung, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
BACKGROUND AND AIM: We evaluated pCLE in the margin delineation of early gastric cancer (EGC) for endoscopic submucosal dissection (ESD) in comparison with white-light imaging with chromoendoscopy (CE). METHODS: We conducted a prospective, randomized controlled study from November 2013 to October 2014 in a tertiary referral hospital. A total of 101 patients scheduled for ESD due to differentiated EGC were randomized into pCLE and CE groups (pCLE 51, CE 50). Markings were made by electrocautery at the proximal and distal tumor margins, as determined by either pCLE or CE...
November 9, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27860300/expert-consensus-on-perioperative-use-of-medications-during-endoscopic-submucosal-dissection-esd-for-gastric-lesions-2015-suzhou-china
#13
Yu Bai, Jian-Ting Cai, You Xiang Chen, Fei Gao, Xiao Zhong Guo, Xue Gang Guo, Ying Han, Jian Yu Hao, Shui Xiang He, Ming Ji, Bo Jiang, Hui Qing Jiang, Zhen Dong Jin, Yan Qing Li, Zhao Shen Li, Zhuan Liao, Feng Liu, Zhi Guo Liu, He Sheng Luo, Bin Lv, Nong Hua Lv, Xu Ren, Jian Qiu Sheng, Rui Hua Shi, De An Tian, Fang Yu Wang, Gui Qi Wang, Ai Ming Yang, Guo Xin Zhang, Zhen Yu Zhang, Fa Chao Zhi, Duo Wu Zou, Xiao Ping Zou
No abstract text is available yet for this article.
November 11, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27858210/novel-effective-and-repeatedly-available-ring-thread-counter-traction-for-safer-colorectal-endoscopic-submucosal-dissection
#14
Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Shintaro Fujihara, Tae Matsunaga, Tsutomu Masaki
BACKGROUND: Although several methods to create an effective counter traction for safer endoscopic submucosal dissection (ESD) have been reported, these methods do not overcome problems regarding delivery and ease of use. This randomized prospective study assessed the usefulness of ring-shaped thread counter traction, which not only allowed the safer colorectal ESD but also the easiest and lower cost counter traction without any special devices. METHODS: Forty-five patients diagnosed with colorectal lateral spreading tumors over 20 mm were allocated to the conventional ESD group (CE) (n = 22) and the ring-shaped thread counter traction ESD group (RE) (n = 21)...
November 17, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27853736/transplantation-of-epidermal-cell-sheets-by-endoscopic-balloon-dilatation-to-avoid-esophageal-re-strictures-initial-experience-in-a-porcine-model
#15
Shinichiro Kobayashi, Nobuo Kanai, Nobuyuki Tanaka, Masanori Maeda, Takahiro Hosoi, Fumio Fukai, Susumu Eguchi, Masayuki Yamato
Background and study aims: Epidermal cell sheet (ECS) transplantation immediately after aggressive endoscopic submucosal dissection (ESD) has been shown to be safe and effective in the prevention of esophageal strictures. This study evaluated the feasibility of ECS transplantation after endoscopic balloon dilation (EBD) in a porcine model. Methods: Six pigs underwent circumferential esophageal ESD under general anesthesia. Two weeks later, two pigs underwent EBD and transplantation of an autologous ECS, two underwent EBD alone, and two underwent endoscopic observation only (control)...
November 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27852546/predictive-factors-for-technically-difficult-endoscopic-submucosal-dissection-in-large-colorectal-tumors
#16
Yuqi He, Xin Wang, Yongqiang Du, Victoria Yee-Wa Yung, Peng Jin, Jianqiu Sheng
BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) for colorectal tumors is dangerous, particularly those that are large. However, the technical difficulty in resecting large tumors in the colonrectum has seldom been investigated. MATERIALS AND METHODS: Between October 2012 and January 2015, 36 consecutive large colorectal tumors were resected by ESD at the endoscopic center of PLA Army General Hospital. Five factors were investigated in predicting the technical difficulty in resecting such tumors...
November 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/27843426/successful-endoscopic-submucosal-dissection-of-a-large-terminal-ileal-lipoma
#17
Hisatsugu Noda, Naotaka Ogasawara, Yasuhiro Tamura, Yoshihiro Kondo, Shinya Izawa, Masahide Ebi, Yasushi Funaki, Makoto Sasaki, Kunio Kasugai
A 78-year-old woman who had recurrent right lower abdominal pain for about 1 year underwent computed tomography (CT) because of a follow-up observation 1 year after right breast cancer surgery. CT revealed a tumor in the colon. The patient was referred to our hospital for detailed examinations. An abdominal CT showed a low-density tumor of approximately 30 mm in the ascending colon, and the CT density inside the tumor was same as that of fatty tissues. A subsequent colonoscopy showed a submucosal tumor (SMT) in the proximal ascending colon developing from the terminal ileum...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27829943/efficacy-of-deep-biopsy-for-subepithelial-lesions-in-the-upper-gastrointestinal-tract
#18
Rolandas Vaicekauskas, Juozas Stanaitis, Jonas Valantinas
INTRODUCTION: Accurate diagnosis of subepithelial lesions (SELs) in the gastrointestinal tract depends on a variety of methods: endoscopy, endoscopic ultrasound and different types of biopsy. Making an error-free diagnosis is vital for the subsequent application of an appropriate treatment. AIM: To evaluate the efficacy of deep biopsy via the endoscopic submucosal dissection (ESD) technique for SELs in the upper gastrointestinal tract. MATERIAL AND METHODS: It was a case series study...
2016: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/27826499/fabrication-and-characterization-of-branched-carbon-nanostructures
#19
Sharali Malik, Yoshihiro Nemoto, Hongxuan Guo, Katsuhiko Ariga, Jonathan P Hill
Carbon nanotubes (CNTs) have atomically smooth surfaces and tend not to form covalent bonds with composite matrix materials. Thus, it is the magnitude of the CNT/fiber interfacial strength that limits the amount of nanomechanical interlocking when using conventional CNTs to improve the structural behavior of composite materials through reinforcement. This arises from two well-known, long standing problems in this research field: (a) inhomogeneous dispersion of the filler, which can lead to aggregation and (b) insufficient reinforcement arising from bonding interactions between the filler and the matrix...
2016: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/27822683/clinical-outcomes-of-endoscopic-submucosa-dissection-for-high-grade-dysplasia-from-endoscopic-forceps-biopsy
#20
Dae Gon Ryu, Cheol Woong Choi, Dae Hwan Kang, Hyung Wook Kim, Su Bum Park, Su Jin Kim, Hyeong Seok Nam
BACKGROUND AND STUDY AIMS: Although the Vienna Classification recommends endoscopic resection for gastric high-grade dysplasia (HGD), many resected lesions are diagnosed as gastric cancer after endoscopic resection. This study aims to evaluate the clinical outcomes of gastric HGD identified by endoscopic forceps biopsy (EFB) after endoscopic submucosal dissection (ESD) and factors associated with discrepant results. PATIENTS AND METHODS: From December 2008 to July 2015, a total of 427 lesions diagnosed as initial HGD by EFB were enrolled...
November 7, 2016: Gastric Cancer
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