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https://www.readbyqxmd.com/read/28230852/single-locoregional-triamcinolone-injection-immediately-after-esophageal-endoscopic-submucosal-dissection-prevents-stricture-formation
#1
Yasuaki Nagami, Masatsugu Shiba, Masaki Ominami, Taishi Sakai, Hiroaki Minamino, Shusei Fukunaga, Satoshi Sugimori, Fumio Tanaka, Noriko Kamata, Tetsuya Tanigawa, Hirokazu Yamagami, Toshio Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa
OBJECTIVES: Although endoscopic submucosal dissection (ESD) is an efficient treatment for superficial esophageal cancer, it is associated with stricture formation after wide-circumference resection that leads to a low quality of life. Although locoregional steroid injections prevent stricture formation, a randomized comparative study did not report any advantages associated with steroid injection. We evaluated the prophylactic efficacy of a single locoregional triamcinolone injection for stricture formation after esophageal ESD...
February 23, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28227705/an-affordable-cuff-less-blood-pressure-estimation-solution
#2
Monika Jain, Niranjan Kumar, Sujay Deb, Monika Jain, Niranjan Kumar, Sujay Deb, Monika Jain, Sujay Deb, Niranjan Kumar
This paper presents a cuff-less hypertension pre-screening device that non-invasively monitors the Blood Pressure (BP) and Heart Rate (HR) continuously. The proposed device simultaneously records two clinically significant and highly correlated biomedical signals, viz., Electrocardiogram (ECG) and Photoplethysmogram (PPG). The device provides a common data acquisition platform that can interface with PC/laptop, Smart phone/tablet and Raspberry-pi etc. The hardware stores and processes the recorded ECG and PPG in order to extract the real-time BP and HR using kernel regression approach...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226350/-value-of-endoscopy-application-in-the-management-of-complications-after-radical-gastrectomy-for-gastric-cancer
#3
Yiqun Zhang, Pinghong Zhou
Endoscopy plays an important role in the diagnosis and treatment of postoperative complications of gastric cancer. Endoscopic intervention can avoid the second operation and has attracted wide attention. Early gastric anastomotic bleeding after gastrectomy is the most common. With the development of technology, emergency endoscopy and endoscopic hemostasis provide a new treatment approach. According to the specific circumstances, endoscopists can choose metal clamp to stop bleeding, electrocoagulation hemostasis, local injection of epinephrine or sclerotherapy agents, and spraying specific hemostatic agents...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28224238/a-non-randomized-confirmatory-trial-of-an-expanded-indication-for-endoscopic-submucosal-dissection-for-intestinal-type-gastric-cancer-ct1a-the-japan-clinical-oncology-group-study-jcog0607
#4
Noriaki Hasuike, Hiroyuki Ono, Narikazu Boku, Junki Mizusawa, Kohei Takizawa, Haruhiko Fukuda, Ichiro Oda, Hisashi Doyama, Kazuhiro Kaneko, Shinichiro Hori, Hiroyasu Iishi, Yukinori Kurokawa, Manabu Muto
BACKGROUND: Endoscopic resection has been limited to intestinal-type gastric cancer (cT1a) with a low risk of lymph node metastasis (T1a ≤2 cm, without ulcers). This single-arm confirmatory trial evaluated the efficacy and safety of endoscopic submucosal dissection (ESD) for >2 cm ulcer-negative and ≤3 cm ulcer-positive intestinal-type gastric cancer (cT1a). METHODS: The eligibility criteria included endoscopically diagnosed cT1a, a single primary intestinal-type gastric adenocarcinoma, an ulcer-negative lesion of any size or a ≤3 cm ulcer-positive lesion, cN0M0, and no prior treatment...
February 21, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28220962/long-term-outcomes-of-endoscopic-submucosal-dissection-versus-laparoscopic-resection-for-gastric-stromal-tumors-less-than-2%C3%A2-cm
#5
Yan Meng, Wei Li, Lu Han, Aimin Li, Qun Yan, Qiuhua Lai, Side Liu, Yue Li
BACKGROUND & AIMS: Laparoscopic resection (LAP) and endoscopic submucosal dissection (ESD) of small gastrointestinal stromal tumors (GISTs) has been reported by large amount of literature. However, the management of small GISTs remains controversial. This study evaluated the efficacy of ESD and LAP for small gastric GISTs and provided long-term outcomes of the two methods. METHODS: A total of 126 patients who underwent ESD or LAP for small gastric GISTs between 2009 and 2016 were retrospectively collected from medical records in our hospital and we made telephone follow-up about recurrence rate...
February 21, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28219464/effect-of-egg-storage-duration-and-brooding-temperatures-on-chick-growth-intestine-morphology-and-nutrient-transporters
#6
S Yalcin, I Gursel, G Bilgen, B H Horuluoglu, G Gucluer, G T Izzetoglu
The effects of egg storage duration (ESD) and brooding temperature (BT) on BW, intestine development and nutrient transporters of broiler chicks were investigated. A total of 396 chicks obtained from eggs stored at 18°C for 3 days (ESD3-18°C) or at 14°C for 14 days (ESD14-14°C) before incubation were exposed to three BTs. Temperatures were initially set at 32°C, 34°C and 30°C for control (BT-Cont), high (BT-High) and low (BT-Low) BTs, respectively. Brooding temperatures were decreased by 2°C each at days 2, 7, 14 and 21...
February 21, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28211807/two-dimensional-shear-wave-elastography-of-breast-lesions-comparison-of-two-different-systems
#7
Wei-Wei Ren, Xiao-Long Li, Ya-Ping He, Dan-Dan Li, Dan Wang, Chong-Ke Zhao, Xiao-Wan Bo, Bo-Ji Liu, Wen-Wen Yue, Hui-Xiong Xu
OBJECTIVE: To evaluate the diagnostic performance of two different shear wave elastography (SWE) techniques in distinguishing malignant breast lesions from benign ones. MATERIALS AND METHODS: From March 2016 to May 2016, a total of 153 breast lesions (mean diameter, 16.8 mm±10.5; range 4.1-90.0 mm) in 153 patients (mean age, 46.4 years±15.1; age range 20-86 years) were separately performed by two different SWE techniques (i.e. T-SWE, Aplio500, Toshiba Medical System, Tochigi, Japan; and S-SWE, the Aixplorer US system, SuperSonic Imagine, Provence, France)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28210705/gastric-esd-may-be-useful-as-accurate-staging-and-decision-of-future-therapeutic-strategy
#8
Ai Fujimoto, Osamu Goto, Toshihiro Nishizawa, Yasutoshi Ochiai, Joichiro Horii, Tadateru Maehata, Teppei Akimoto, Satoshi Kinoshita, Seiji Sagara, Motoki Sasaki, Toshio Uraoka, Naohisa Yahagi
Background and study aims We sometimes perform gastric endoscopic submucosal dissection (ESD) for total pathologic diagnosis when preoperative diagnosis is difficult. In the present study we analyzed the treatment outcomes and adverse events of diagnostic ESD for early gastric cancer (EGC). Patients and methods We conducted a retrospective analysis of 18 consecutive cases of EGC in 18 patients with a suspected out-of-indication diagnosis who underwent diagnostic ESD, between June 2010 and November 2014...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28210084/risk-factors-for-intraoperative-perforation-during-endoscopic-submucosal-dissection-of-superficial-esophageal-squamous-cell-carcinoma
#9
Masaaki Noguchi, Tomonori Yano, Tomoji Kato, Tomohiro Kadota, Maomi Imajoh, Hiroyuki Morimoto, Shozo Osera, Atsushi Yagishita, Tomoyuki Odagaki, Yusuke Yoda, Yasuhiro Oono, Hiroaki Ikematsu, Kazuhiro Kaneko
AIM: To identify the risk factors and clarify the subsequent clinical courses. METHODS: This study retrospectively analyzed consecutive patients with esophageal squamous cell carcinoma (ESCC) treated using endoscopic submucosal dissection (ESD) between April 2008 and October 2012. We divided the ESCC lesions into perforation cases and non-perforation cases, and compared characteristics and endoscopic findings between the two groups. "Intraoperative perforation" was defined as the detection of a perforation site during ESD and the presence of mediastinal emphysema...
January 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28202938/prognostic-value-of-microrna-signature-in-patients-with-gastric-cancers
#10
Hai-Ting Liu, Ya-Wen Wang, Ai-Yan Xing, Duan-Bo Shi, Hui- Zhang, Xiang-Yu Guo, Jing- Xu, Peng Gao
The occurrence of lymph node metastases (LNM) after endoscopic submucosal dissection (ESD) in patients with gastric cancer (GC) leads to poor prognosis. However, few biomarkers are available to predict LNM in GC patients. Thus, we measured expression of 6 cancer-related miRNAs using real-time RT-PCR in 102 GC samples that were randomized into a training set and a testing set (each, 51 cases). Using logistic regression, we identified 4-miRNA (miR-27b, miR-128, miR-100 and miR-214) signatures for predicting LNM in GC patients...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28191493/endoscopic-submucosal-dissection-for-early-gastric-cancer-in-very-elderly-patients-age-85-or-older
#11
Ko Watanabe, Takuto Hikichi, Jun Nakamura, Tadayuki Takagi, Rei Suzuki, Mitsuru Sugimoto, Yuichi Waragai, Hitomi Kikuchi, Naoki Konno, Hiroyuki Asama, Mika Takasumi, Katsutoshi Obara, Hiromasa Ohira
Background and study aims The safety and efficacy of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) in very elderly patients remains unclear. The aim of this study was to evaluate the safety and efficacy of ESD for EGC in patients age 85 years and older. Patients and methods Patients who underwent ESD for EGC between September 2003 and April 2015 were divided into 3 groups: the very elderly (≥ 85 years; 43 patients), the elderly (65 - 84 years; 511 patients), and the non-elderly ( ≤ 64 years; 161 patients)...
January 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28188417/the-efficacy-of-endoscopic-submucosal-dissection-for-colorectal-tumors-extending-to-the-dentate-line
#12
Satohiro Matsumoto, Hirosato Mashima
PURPOSE: Although endoscopic submucosal dissection (ESD) is becoming the mainstay of the treatment strategies, rather than surgical treatment, for colorectal tumors extending to the dentate line, ESD is technically more difficult. This study was aimed at assessing the usefulness of ESD for the treatment of colorectal tumors extending to the dentate line. METHODS: This study included 531 patients with colorectal tumors who underwent colorectal ESD between 2008 and 2015...
February 10, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28187927/value-of-shear-wave-elastography-in-the-diagnosis-of-gouty-and-non-gouty-arthritis
#13
Yuanjiao Tang, Feng Yan, Yujia Yang, Xi Xiang, Liyun Wang, Lingyan Zhang, Li Qiu
Our aim was to analyze the diagnostic performance of shear wave elastography (SWE) in the diagnosis of gouty arthritis (GA) and non-gouty arthritis (non-GA). Thirty-nine patients in the GA group and 55 patients in the non-GA group were included in the study. Based on the echo intensity of the joint lesions, the GA group was subdivided into hypo-echoic GA, slightly hyper-echoic GA and hyper-echoic GA subgroups. Quantitative SWE features were evaluated and receiver operating characteristic analysis was performed...
February 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28186115/stable-cretaceous-sex-chromosomes-enable-molecular-sexing-in-softshell-turtles-testudines-trionychidae
#14
Michail Rovatsos, Peter Praschag, Uwe Fritz, Lukáš Kratochvšl
Turtles demonstrate variability in sex determination ranging from environmental sex determination (ESD) to highly differentiated sex chromosomes. However, the evolutionary dynamics of sex determining systems in this group is not well known. Differentiated ZZ/ZW sex chromosomes were identified in two species of the softshell turtles (Trionychidae) from the subfamily Trionychinae and Z-specific genes were identified in a single species. We tested Z-specificity of a subset of these genes by quantitative PCR comparing copy gene numbers in male and female genomes in 10 species covering the phylogenetic diversity of trionychids...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28180953/colorectal-esd-in-day-surgery
#15
Tomohiko Ohya, Richard Marsk, Klas Pekkari
BACKGROUND: Colorectal endoscopic submucosal dissection (ESD) was developed in Japan and is growing in popularity in Europe. Patients undergoing a colorectal ESD procedure in Japan are hospitalized for several days. In this study, we investigated the feasibility of colorectal ESD as an outpatient procedure in a European setting. METHODS: A prospective cohort of all patients undergoing colorectal ESD at Danderyds Hospital, Stockholm, Sweden from April 2014 to December 2015 were studied...
February 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28174124/endoscopic-treatment-outcomes-of-laterally-spreading-tumors-with-a-skirt-with-video
#16
Shozo Osera, Hiroaki Ikematsu, Satoshi Fujii, Keisuke Hori, Yasuhiro Oono, Tomonori Yano, Kazuhiro Kaneko
BACKGROUND AND AIMS: A "skirt" is a slightly elevated flat lesion with wide pits occasionally observed at the margin of laterally spreading tumors (LSTs). However, the endoscopic treatment outcomes of LSTs with skirts have not been clarified. The aim of this study was to evaluate the endoscopic treatment outcomes of LSTs with skirts. METHODS: Between February 2006 and March 2014, 996 LSTs were retrospectively examined to assess the clinicopathological characteristics, procedure time, en bloc resection rate, R0 resection rate, adverse events, and local recurrence rate of endoscopic submucosal dissection (ESD); and the local recurrence rate of endoscopic resection...
February 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28171690/endoscopic-submucosal-dissection-of-a-large-neoplastic-lesion-at-ileorectal-anastomosis-in-a-fap-patient
#17
Stefano Sansone, Takeshi Nakajima, Yutaka Saito
Endoscopic submucosal dissection (ESD) may remove gastrointestinal neoplasias even associated with severe fibrosis [1-3]. We report the first case of ESD for a large neoplasia located in the remnant rectum after total colectomy in a patient with familial adenomatous polyposis (FAP). A 19 year old female with FAP underwent total colectomy with ileorectal anastomosis (IRA). Fourteen years later a surveillance endoscopy revealed a 0-Is+IIa lesion, measuring 75mm, occupying the "dog ear" portion of the rectum and involving the IRA (fig 1a-b)...
February 7, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28163289/a-case-of-metachronous-liver-metastasis-from-neuroendocrine-carcinoma-of-the-stomach-at-1-year-and-10-months-after-endoscopic-submucosal-dissection
#18
Masafumi Hashiguchi, Tsutomu Tamai, Yuuichiro Nasu, Fumisato Sasaki, Michiyo Higashi, Kaoru Hijikuro, Hisatomo Futawatari, Kouichirou Shigeta, Susumu Hasegawa, Akio Ido
A 77-year-old man underwent endoscopic submucosal dissection (ESD) of a type 0-IIc tumor located in the cardiac part of the stomach. The pathological diagnosis of the tumor was poorly differentiated tubular adenocarcinoma with submucosal invasion depth;therefore, radical gastrectomy was also performed. After 1 year and 10 months, liver metastasis was detected because of which partial liver resection was performed. The pathological diagnosis of the tumor was neuroendocrine carcinoma (NEC). The pathology of the ESD specimen was re-examined, and a diagnosis of gastric NEC was made;furthermore, the liver tumor was regarded as metachronous metastasis...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28161819/optimizing-resection-of-large-colorectal-polyps
#19
REVIEW
Steven J Heitman, David J Tate, Michael J Bourke
Polypectomy reduces the incidence and mortality of colorectal cancer (CRC). The widespread adoption of CRC screening, more rigorous colonoscopy techniques, and advancements in endoscopic imaging have led to a greater awareness of complex polyps. Whereas surgery was once considered necessary for many large sessile or laterally spreading lesions (LSLs) in the colorectum, the majority can now be removed endoscopically. Endoscopic mucosal resection (EMR) is an established technique for treatment of colorectal LSLs...
February 4, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28159540/complex-early-barrett-s-neoplasia-at-3-western-centers-european-barrett-s-endoscopic-submucosal-dissection-trial-e-best
#20
Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett's neoplasia and has advantages over conventional endoscopic mucosal resection (EMR) as it enables en bloc resection and accurate histopathological analysis of cancer resection margins. However, its long learning curve and higher adverse event rate has tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett's neoplasia...
January 31, 2017: Gastrointestinal Endoscopy
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