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https://www.readbyqxmd.com/read/28522954/current-practices-in-endoscopic-submucosal-dissection-for-colorectal-neoplasms-a-survey-of-indications-among-korean-endoscopists
#1
Tae Jun Kim, Eun Ran Kim, Sung Noh Hong, Young-Ho Kim, Dong Kyung Chang
BACKGROUND/AIMS: The indications for colorectal endoscopic submucosal dissection (ESD) vary in clinical practice. To establish colorectal ESD as a standard treatment, standard indications are essential. For establishing standard indications for colorectal ESD, we surveyed the preferences and criteria of endoscopists for colorectal ESD in their practices. METHODS: A multiple-choice questionnaire was sent to 27 members of the Korean Society of Gastrointestinal Endoscopy/ESD group...
April 2017: Intestinal Research
https://www.readbyqxmd.com/read/28522906/magnetic-anchor-guidance-for-endoscopic-submucosal-dissection-and-other-endoscopic-procedures
#2
REVIEW
Mohamed Mortagy, Neal Mehta, Mansour A Parsi, Seiichiro Abe, Tyler Stevens, John J Vargo, Yutaka Saito, Amit Bhatt
Endoscopic submucosal dissection (ESD) is a well-established, minimally invasive treatment for superficial neoplasms of the gastrointestinal tract. The universal adoption of ESD has been limited by its slow learning curve, long procedure times, and high risk of complications. One technical challenge is the lack of a second hand that can provide traction, as in conventional surgery. Reliable tissue retraction that exposes the submucosal plane of dissection would allow for safer and more efficient dissection...
April 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28516756/carbon-dioxide-versus-air-insufflation-in-gastric-endoscopic-submucosal-dissection-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
Ramkaji Baniya, Sunil Upadhaya, Jahangir Khan, Suresh K Subedi, Tabrez S Mohammed, Balvant K Ganatra, Ghassan Bachuwa
Background/Aims: Endoscopic submucosal dissection (ESD) with air insufflation is commonly used for the staging and treatment of early gastric carcinoma. However, carbon dioxide (CO2) use has been shown to cause less post-procedural pain and fewer adverse events. The objective of this study was to compare the post-procedural pain and adverse events associated with CO2 and air insufflation in ESD. Methods: A systematic search was conducted for randomized control trials (RCTs) comparing the two approaches in ESD...
May 18, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28502928/endoscopic-submucosal-dissection-for-depressed-type-early-adenocarcinoma-of-the-terminal-ileum
#4
Keitaro Takahashi, Takahiro Ito, Tomonobu Sato, Mitsuru Goto, Toru Kawamoto, Akihiro Fujinaga, Nobuyuki Yanagawa, Yoshinori Saito, Keisuke Sato, Mikihiro Fujiya
We herein report a rare case of ileal adenocarcinoma that was completely removed by endoscopic submucosal dissection (ESD) without any complications. An 80-year-old man was referred to our hospital to undergo treatment for an ileal tumor. Conventional colonoscopy showed a reddish depressed lesion that was classified as type 0-IIc according to the Paris classification. The ileal tumor was successfully removed en bloc by ESD with a negative surgical margin. The histological findings showed a well-differentiated adenocarcinoma with no submucosal or lymphovascular invasion...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28502883/comparative-evaluation-of-colonoscopy-assisted-transanal-minimally-invasive-surgery-via-glove-port-and-endoscopic-submucosal-dissection-for-early-rectal-tumor
#5
Weiming Mao, Xiujun Liao, Shuxian Shao, Wenjing Wu, Yanyan Yu, Guangen Yang
BACKGROUND: Early rectal tumor is usually managed by local excision. A novel method-colonoscopy-assisted transanal minimally invasive surgery via glove port (CA-TAMIS-GP)-for resecting early rectal tumor was developed and compared with endoscopic submucosal dissection (ESD). MATERIALS AND METHODS: We performed CA-TAMIS-GP surgery on 26 patients from January 2014 to February 2016. For better analysis, we retrospectively collected data from 31 patients who underwent ESD between October 2012 and December 2013; overall, 57 patients diagnosed with early rectal tumor were included in this study...
May 11, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28491139/traction-using-a-clip-with-line-is-a-preferred-method-for-trainees-in-performing-esophageal-endoscopic-submucosal-dissection-an-animal-model-study
#6
Peng Jin, Kuang-I Fu, Yang Yu, Yu-Qi He, Zhi Wei, Xin Wang, Qiang Cai, Jian-Qiu Sheng
BACKGROUND: The optimal operative process of esophageal endoscopic submucosal dissection (ESD), especially for the beginners, is not established. In this study, the clip-with-line method, the tunneling method and the conventional method for esophageal ESD were compared in a training course on live pigs. METHODS: 15 trainee endoscopists were randomized into three groups, the clip-with-line method group, the tunneling method group, and the conventional method group...
April 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28484889/the-value-of-diagnostic-endoscopic-submucosal-dissection-for-patients-with-clinical-submucosal-invasive-early-gastric-cancer
#7
Keiichi Fujiya, Kohei Takizawa, Masanori Tokunaga, Noboru Kawata, Makoto Hikage, Rie Makuuchi, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Masaki Tanaka, Naomi Kakushima, Hiroyuki Ono, Masanori Terashima
BACKGROUND: The standard treatment for clinical submucosal invasive (cT1b) early gastric cancer is gastrectomy. However, Japanese gastric cancer treatment guidelines list endoscopic submucosal dissection (ESD) as an option for treating limited early gastric cancer cases. ESD can be curative depending on the pathological characteristics of resected specimens. Thus, we aimed to clarify the benefits and disadvantages of preceding ESD for early gastric cancer. METHODS: We retrospectively analyzed patients who underwent ESD or curative gastrectomy for cT1b gastric cancer with differentiated adenocarcinoma 30 mm or less in diameter...
May 8, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28484737/management-of-early-gastric-cancer-with-positive-horizontal-or-indeterminable-margins-after-endoscopic-submucosal-dissection-multicenter-survey
#8
Naoki Ishii, Fumio Omata, Junko Fujisaki, Toshiaki Hirasawa, Mitsuru Kaise, Shu Hoteya, Satoshi Tanabe, Kenji Ishido, Ken Ohata, Maiko Takita, Tetsuya Mine, Muneki Igarashi, Tatsuya Yoshida, Yuichi Takeda, Yohei Furumoto, Kenshi Matsumoto, Naohisa Yahagi, Hirotaka Nakashima, Tomonori Wada, Tomoko Tagata, Atsushi Mitsunaga
Background and study aims Positive horizontal margins in resected specimens are sometimes encountered after endoscopic submucosal dissection (ESD) for early gastric cancers, and appropriate treatment strategies for these cases are not established. The aim of this study was to evaluate current empirical treatments for patients with positive horizontal or indeterminable margins after ESD. Patients and methods We performed a multicenter survey and data from 14 hospitals were collected. The pooled proportions of positive horizontal or indeterminable margins and those of patients followed up without early intervention were calculated using a logistic-normal random-effects model...
May 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28484736/continuous-use-of-low-dose-warfarin-for-gastric-endoscopic-submucosal-dissection-a-prospective-study
#9
Hideaki Harada, Satoshi Suehiro, Daisuke Murakami, Takanori Shimizu, Ryotaro Nakahara, Yasushi Katsuyama, Yasunaga Miyama, Shigetaka Tounou, Kenji Hayasaka
Background and study aims Patients who receive warfarin usually require heparin bridge therapy (HBT) to prevent thromboembolic events during endoscopic submucosal dissection (ESD); however, clinical evidence demonstrating the safety and efficacy of HBT during gastric ESD is limited. Conversely, warfarin can be continuously used as a substitute for HBT to endoscopic procedures which have a low risk of bleeding. This study aimed to clarify the safety and efficacy of continuous low-dose warfarin (LDW) for gastric ESD...
May 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28477321/the-abdominal-radiation-doses-for-paediatric-patients-undergoing-x-ray-examinations-at-southern-saudi-arabia
#10
Jobran Miree Alqahtani
This study aims to estimate radiation doses for paediatric patients undergoing abdominal X-ray examinations in Najran, Saudi Arabia, through evaluation of the entrance surface doses using DoseCal software. Two X-ray units were used at a paediatric referral hospital. A total of 216 patients were examined with an age range between 0 and 7 years. The mean ESDs were found to be 0.042 and 0.101 mGy, for abdomen anteroposterior (AP) and posteroanterior (PA) respectively. The results are useful to the National Centre for Radiation Protection in Saudi Arabia and other professional organizations elsewhere, to set up safety protocols to prevent paediatric patients from needless radiation and to establish diagnostic reference levels (DRLs)...
May 5, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28475742/risk-of-metachronous-recurrence-after-endoscopic-submucosal-dissection-of-esophageal-squamous-cell-carcinoma
#11
K Uno, T Koike, G Kusaka, Y Takahashi, N Ara, T Shimosegawa
Development of endoscopic submucosal dissection (ESD) improves the en bloc resection rate of superficial esophageal squamous cell carcinoma (SESCC). Although the background mucosa after ESD remains malignant potential, esophageal (sub)circumferential ESD, in cases where the mucosal defect is greater than three-fourths of the circumference, might induce refractory stricture, and it may disturb early detection of the recurrence. Therefore, we aimed to elucidate whether the patients treated by (sub)circumferential ESD for SESCC may remain at risk of metachronous recurrence...
June 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28471645/large-energy-density-excellent-thermal-stability-and-high-cycling-endurance-of-lead-free-bazr0-2ti0-8o3-film-capacitors
#12
Zixiong Sun, Chunrui Ma, Xi Wang, Ming Liu, Lu Lu, Ming Wu, Xiaojie Lou, Hong Wang, Chun-Lin Jia
A large energy storage density (ESD) of 30.4 J/cm(3) and high energy efficiency of 81.7% under an electrical field of 3 MV/cm was achieved at room temperature by the fabrication of environmentally friendly lead-free BaZr0.2Ti0.8O3 epitaxial thin films on Nb-doped SrTiO3 (001) substrates by using a radio-frequency magnetron sputtering system. Moreover, the BZT film capacitors exhibit great thermal stability of the ESD from 16.8 J/cm(3) to 14.0 J/cm(3) with efficiency of beyond 67.4% and high fatigue endurance (up to 10(6) cycles) in a wide temperature range from room temperature to 125 °C...
May 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28467024/endoluminal-surgical-triangulation-2-0-a-new-flexible-surgical-robot-preliminary-pre-clinical-results-with-colonic-submucosal-dissection
#13
András Légner, Michele Diana, Péter Halvax, Yu-Yin Liu, Lucile Zorn, Philippe Zanne, Florent Nageotte, Michel De Mathelin, Bernard Dallemagne, Jacques Marescaux
BACKGROUND: Complex intraluminal surgical interventions of the gastrointestinal tract are challenging due to the limitation of existing instruments. Our group has developed a master-slave robotic flexible endoscopic platform that provides instrument triangulation in an endoluminal environment. MATERIALS AND METHODS: Colonic endoscopic submucosal dissections (ESD) were carried out in eight pigs. The robot was introduced transanally. A combination of adapted tele-operated instruments was used...
May 3, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28457631/quantitative-assessment-of-skin-stiffness-in-localized-scleroderma-using-ultrasound-shear-wave-elastography
#14
Liyun Wang, Feng Yan, Yujia Yang, Xi Xiang, Li Qiu
The purpose of this study was to evaluate the usefulness of ultrasound shear-wave elastography (US-SWE) in characterization of localized scleroderma (LS), as well as in the disease staging. A total of 21 patients with 37 LS lesions were enrolled in this study. The pathologic stage (edema, sclerosis or atrophy) of the lesions was characterized by pathologic examination. The skin elastic modulus (E-values including Emean, Emin, Emax and Esd) and thickness (h) was evaluated both in LS lesions and site-matched unaffected skin (normal controls) using US-SWE...
April 27, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28446997/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-early-stage-esophageal-cancer
#15
REVIEW
Bo Ning, Mohamed M Abdelfatah, Mohamed O Othman
Mortality from esophageal cancer remains high despite advances in medical therapy. Although the incidence of squamous cell carcinoma of the esophagus remains unchanged, the incidence of the esophageal adenocarcinoma has increased over time. Gastroesophageal reflux disease (GERD and obesity are contributing factors to the development of Barrett's esophagus and subsequent development of adenocarcinoma. Early recognition of the disease can lead to resection of esophageal cancer prior to the development of lymphovascular invasion...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28445280/clinical-outcome-after-endoscopic-submucosal-dissection-for-early-gastric-cancer-of-absolute-and-expanded-indication
#16
Ju Seok Kim, Sun Hyung Kang, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee, Hyun Yong Jeong
This study evaluated the clinical outcome of endoscopic submucosal dissection (ESD) in minute submucosa (SM) invasion or undifferentiated early gastric cancer (EGC) and analyzed factors related to local recurrence after ESD.We retrospectively reviewed the chart of EGC patients, who underwent ESD at our tertiary hospital between January 2009 and 2015. The patients' characteristics and clinical outcomes were compared among an absolute indication, minute SM invasion, and undifferentiated EGC group.Of 885 total patients, 729 composed the absolute indication group; 65, the differentiated, SM invasion group; and 51, the undifferentiated, confined mucosa group...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28434216/can-endoscopic-ulcerations-in-early-gastric-cancer-be-clearly-defined-before-endoscopic-resection-a-survey-among-endoscopists
#17
Sung Min Park, Byung-Wook Kim, Joon Sung Kim, Young Wook Kim, Gi Jun Kim, Seung Ji Ryu
Background/Aims: Early gastric cancer (EGC) with ulcerations can be treated via endoscopic resection (ER) when it is differentiated pathologically, limited to the mucosa, and <3 cm in diameter. The presence of ulceration is a key factor in deciding treatment strategies and is usually diagnosed during endoscopic examination. The aim of this study was to evaluate whether ulcerations in EGC can be clearly defined among endoscopists and which factors are related to the differences. Methods: A survey questionnaire, composed of demographic features and endoscopic images of seven patients with EGC, was presented to the endoscopists via e-mail...
April 24, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28425665/standardization-of-endoscopic-resection-for-colorectal-tumors-larger-than-10%C3%A2-mm-in-diameter
#18
Shiro Oka, Toshio Uraoka, Naoto Tamai, Hiroaki Ikematsu, Akiko Chino, Koichi Okamoto, Yoji Takeuchi, Kenichiro Imai, Ken Ohata, Hisashi Shiga, Spiro Raftopoulos, Bo-In Lee, Takahisa Matsuda
Currently, several endoscopic resection (ER) methods for colorectal tumors are available, including polypectomy, conventional endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and modified ER. In the present review, we mainly focus on the current status of ER for colorectal tumors as well as the report from the Endoscopic Forum Japan (EFJ) 2016, which was held in Tokyo in August 2016. The proposed ER methods for colorectal tumors larger than 10 mm in diameter are as follows. (i) Pedunculated-type tumor is an indication for polypectomy, regardless of size...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28425662/feasibility-of-colorectal-endoscopic-submucosal-dissection-esd-carried-out-by-endoscopists-with-no-or-little-experience-in-gastric-esd
#19
Hisashi Shiga, Reina Ohba, Tamotsu Matsuhashi, Mario Jin, Masatake Kuroha, Katsuya Endo, Rintaro Moroi, Shoichi Kayaba, Katsunori Iijima
BACKGROUND AND AIM: Colorectal endoscopic submucosal dissection (ESD) is recommended to be carried out only by endoscopists with sufficient experience in gastric ESD. However, early gastric carcinoma is less common in Western countries than in Japan, and endoscopic maneuverability differs between the stomach and colorectum. We assessed the feasibility of colorectal ESD carried out by endoscopists with no or little experience in gastric ESD. METHODS: We analyzed en bloc resection, R0 resection and perforation rates in 180 consecutive colorectal ESD carried out by three endoscopists who had no or <5 cases of experience in gastric ESD...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28425660/endoscopic-submucosal-dissection-for-large-colorectal-neoplasms
#20
Kenichiro Imai, Kinichi Hotta, Yuichiro Yamaguchi, Sayo Ito, Hiroyuki Ono
BACKGROUND AND AIM: Endoscopic submucosal dissection (ESD) for colorectal neoplasms (CRN) of >50 mm is considered technically difficult. The ITknife nano™ was developed specifically for ESD of CRN and esophageal superficial neoplasms; however, only limited data are available regarding its use in this procedure. Here we assessed the safety and efficacy of ESD using the ITknife nano™ for large CRN (>50 mm). METHODS: We carried out a retrospective study, including consecutive patients with CRN larger than 50 mm that were treated by ESD between September 2002 and August 2016 at our institution...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
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