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organ printing

Robby Janneck, Nicolas Pilet, Satya Prakash Bommanaboyena, Benjamin Watts, Paul Heremans, Jan Genoe, Cedric Rolin
Highly crystalline thin films of organic semiconductors offer great potential for fundamental material studies as well as for realizing high-performance, low-cost flexible electronics. The fabrication of these films directly on inert substrates is typically done by meniscus-guided coating techniques. The resulting layers show morphological defects that hinder charge transport and induce large device-to-device variability. Here, a double-step method for organic semiconductor layers combining a solution-processed templating layer and a lateral homo-epitaxial growth by a thermal evaporation step is reported...
October 10, 2017: Advanced Materials
Joana Cunha-Cruz, Colleen E Huebner, Sharity Ludwig, Jeanne Dysert, Melissa Mitchell, Gary Allen, R Mike Shirtcliff, JoAnna M Scott, Peter Milgrom
INTRODUCTION: Twice-daily caregiver-supervised toothbrushing with fluoridated toothpaste is an effective and widely recommended strategy to prevent tooth decay in children. Qualitative research suggests that low-income caregivers know the recommendation but would benefit from toothbrushing supplies and advice about how to introduce this health behavior especially as the child becomes older and asserts autonomy to do it "myself." Our objective is to assess consumer satisfaction with the evidence-based theory-informed campaign and usefulness of materials that were home delivered...
2017: Frontiers in Public Health
Han-Seung Ko, Yeongjun Lee, Sung-Yong Min, Sung-Joo Kwon, Tae-Woo Lee
Nanowire (NW) complementary inverters based on NW channels and NW electrodes are a promising core logic unit of future subminiature, high density and textile-type configured electronic circuits. However, existing approaches based on short NWs (<150 μm) or non-woven nanofibers cannot provide precisely-coordinated NW inverters due to the difficulty in the position and alignment control of each NW. In particular, the large-scale fabrication of highly-aligned metal nanoelectrode (NE) arrays with low resistivity is a challenging issue...
October 11, 2017: Nanoscale
John P M Finberg, Yuval Aluf, Yelena Loboda, Morad K Nakhleh, Raneen Jeries, Manal Aboud, Salman Zubedat, Avi Avital, Soliman Khatib, Jacob Vaya, Hossam Haick
Early diagnosis of Parkinson's disease (PD) is of great importance due its progressive phenotype. Neuroprotective drugs could potentially slow down disease progression if used at early stages. Previously, we have reported an altered content of volatile organic compounds (VOCs) in the breath of rats following a 50% reduction in striatal dopamine (DA) content induced by 6-hydroxydopamine. We now report on the difference in the breath-print and content of VOCs between rats with mild and severe lesions of DA neurons, serotonergic neuronal lesions, and transgenic (Tg) rats carrying the PD-producing A53T mutation of the SNCA (alpha-synuclein) gene...
October 10, 2017: ACS Chemical Neuroscience
R House, N Rajaram, S M Tarlo
Background: Three-dimensional (3D) printing is being increasingly used in manufacturing and by small business entrepreneurs and home hobbyists. Exposure to airborne emissions during 3D printing raises the issue of whether there may be adverse health effects associated with these emissions. Aims: We present a case of a worker who developed asthma while using 3D printers, which illustrates that respiratory problems may be associated with 3D printer emissions. Case report: The patient was a 28-year-old self-employed businessman with a past history of asthma in childhood, which had resolved completely by the age of eight...
August 23, 2017: Occupational Medicine
Louise Ninett Carlsen, Maria Lurenda Westergaard, Mette Bisgaard, Julie Brogaard Schytz, Rigmor Højland Jensen
Background Medication-overuse headache is prevalent, but in principle preventable. Objective To describe the Danish national awareness campaign for medication-overuse headache. Methods The Danish Headache Center, the Association of Danish Pharmacies, and headache patient organizations implemented a four-month medication-overuse headache awareness campaign in 2016. Target groups were the general public, general practitioners, and pharmacists. Key messages were: Overuse of pain-medication can worsen headaches; pain-medication should be used rationally; and medication-overuse headache is treatable...
January 1, 2017: Cephalalgia: An International Journal of Headache
Changting Wei, Jinyong Zhuang, Dongyu Zhang, Wenrui Guo, Dongfang Yang, Zhong-Zhi Xie, Jian-Xin Tang, Wenming Su, Haibo Zeng, Zheng Cui
Film morphology plays a crucial role in the performance of multi-layered organic light emitting diodes (OLEDs), while there is little reported literature from the angle of molecular level to investigate the impact on film-forming ability and device performance. In this work, four isomeric cross-linkable electron transport materials constructed with pyridine, 1,2,4-triazole and vinylbenzyl ether groups were developed for inkjet-printed OLEDs . Their lowest unoccupied molecular orbital (LUMO: 3.20 eV) and highest occupied molecular orbital (HOMO: 6...
October 10, 2017: ACS Applied Materials & Interfaces
Lhaylla Crissaff, Louisa Wood Ruby, Samantha Deutch, R Luke DuBois, Jean-Daniel Fekete, Juliana Freire, Claudio Silva
Art historians have traditionally used physical light boxes to prepare exhibits or curate collections. On a light box, they can place slides or printed images, move the images around at will, group them as desired, and visually compare them. The transition to digital images has rendered this workflow obsolete. Now, art historians lack well-designed, unified interactive software tools that effectively support the operations they perform with physical light boxes. To address this problem, we designed ARIES (ARt Image Exploration Space), an interactive image manipulation system that enables the exploration and organization of fine digital art...
October 5, 2017: IEEE Computer Graphics and Applications
Yangxiaolu Cao, Yaying Feng, Marc D Ryser, Kui Zhu, Gregory Herschlag, Changyong Cao, Katherine Marusak, Stefan Zauscher, Lingchong You
Biological systems can generate microstructured materials that combine organic and inorganic components and possess diverse physical and chemical properties. However, these natural processes in materials fabrication are not readily programmable. Here, we use a synthetic-biology approach to assemble patterned materials. We demonstrate programmable fabrication of three-dimensional (3D) materials by printing engineered self-patterning bacteria on permeable membranes that serve as a structural scaffold. Application of gold nanoparticles to the colonies creates hybrid organic-inorganic dome structures...
October 9, 2017: Nature Biotechnology
Chin Siang Ong, Pooja Yesantharao, Chen Yu Huang, Gunnar Mattson, Joseph Boktor, Takuma Fukunishi, Huaitao Zhang, Narutoshi Hibino
Recent advances have allowed for three-dimensional (3D) printing technologies to be applied to biocompatible materials, cells and supporting components, creating a field of 3D bioprinting that holds great promise for artificial organ printing and regenerative medicine. At the same time, stem cells, such as human induced pluripotent stem cells, have driven a paradigm shift in tissue regeneration and the modeling of human disease, and represent an unlimited cell source for tissue regeneration and the study of human disease...
October 6, 2017: Pediatric Research
Ani Wang, Ruiqing Fan, Ping Wang, Ru Fang, Sue Hao, Xuesong Zhou, Xubin Zheng, Yulin Yang
This study investigates the mechanism of AIE in the solid state through supramolecular metal-organic frameworks and mechanoluminescent materials for the first time. Herein, four novel differently substituted Schiff base building blocks, SB1-SB4, exhibit typical AIE properties with various fluorescence emissions from yellow to green. SB1-SB4 are linked through C-H···O hydrogen bonding interactions to construct supramolecular metal-organic frameworks (SMOFs): namely, SMOFSB1-SMOFSB4. Particularly, among these SMOFs, SMOFSB3 is observed to have micropores in the 3D supramolecular structure and exhibits mechanoluminescent properties (grinding)...
October 6, 2017: Inorganic Chemistry
Bing Tang, Qianyu Chen, Liying Bin, Shaosong Huang, Wenxiang Zhang, Fenglian Fu, Ping Li
This work aims at establishing a coupling anaerobic-aerobic biofilm within a single bioreactor and revealing its microbial community and succession. By using a semi-suspended bio-carrier fabricated with 3D printing technique, an obvious DO gradient was gradually created within the biofilm, which demonstrated that a coupling anaerobic-aerobic biofilm was successfully established on the surface of bio-carriers. The results of metagenomic analysis revealed that the microbial community on the bio-carriers experienced a continuous succession in its structure and dominant species along with the operational time...
September 22, 2017: Bioresource Technology
Brian Schmatz, Zhibo Yuan, Augustus W Lang, Jeff L Hernandez, Elsa Reichmanis, John R Reynolds
The ability to process conjugated polymers via aqueous solution is highly advantageous for reducing the costs and environmental hazards of large scale roll-to-roll processing of organic electronics. However, maintaining competitive electronic properties while achieving aqueous solubility is difficult for several reasons: (1) Materials with polar functional groups that provide aqueous solubility can be difficult to purify and characterize, (2) many traditional coupling and polymerization reactions cannot be performed in aqueous solution, and (3) ionic groups, though useful for obtaining aqueous solubility, can lead to a loss of solid-state order, as well as a screening of any applied bias...
September 27, 2017: ACS Central Science
Xiaolian Chen, Wenrui Guo, Liming Xie, Changting Wei, Jinyong Zhuang, Wenming Su, Zheng Cui
Metal-mesh is one of the contenders to replace indium tin oxide (ITO) as transparent conductive electrodes (TCEs) for optoelectronic applications. However, considerable surface roughness accompanying with metal-mesh type of transparent electrodes has been the root cause of electrical short-circuiting for optoelectronic devices, such as organic light emitting diode (OLED) and organic photovoltaic (OPV). In this work, a novel approach to making metal-mesh TCE has been proposed, which is based on hybrid printing of silver (Ag) nanoparticle ink and electroplating of nickel (Ni)...
October 2, 2017: ACS Applied Materials & Interfaces
Meik Neufurth, Xiaohong Wang, Shunfeng Wang, Renate Steffen, Maximilian Ackermann, Natalie D Haep, Heinz C Schröder, Werner E G Müller
Here we describe the formulation of a morphogenetically active bio-ink consisting of amorphous microparticles (MP) prepared from Ca(2+) and the physiological inorganic polymer, polyphosphate (polyP). Those MP had been fortified by mixing with poly-ε-caprolactone (PCL) to allow 3D-bioprinting. The resulting granular PCL/Ca-polyP-MP hybrid material, liquefied by short-time heating to 100°C, was used for the 3D-printing of tissue-like scaffolds formed by strands with a thickness of 400 µm and a stacked architecture leaving ≈0...
September 28, 2017: Acta Biomaterialia
Evelyn L Howatt Donahoe, Roger W Rochat, Deborah McFarland, Carlos Del Rio
The objective of this article is to describe summer field experiences at the Rollins School of Public Health. An online survey was conducted among Master of Public Health students returning from summer field experiences. We used printed reports from 2004-2012 and original survey data from 2010-2013 to perform a trend analysis using correlation analysis and linear regression. We found that our students have worked for more than 300 organizations in 84 countries. The average cost of a summer field experience fluctuated around US$3,500, with students receiving an average of US$2,180 in funding...
September 27, 2017: Global Health, Science and Practice
Olga Shalev, Shreya Raghavan, J Maxwell Mazzara, Nancy Senabulya, Patrick D Sinko, Elyse Fleck, Christopher Rockwell, Nicholas Simopoulos, Christina M Jones, Anna Schwendeman, Geeta Mehta, Roy Clarke, Gregory E Amidon, Max Shtein
There is growing need to develop efficient methods for early-stage drug discovery, continuous manufacturing of drug delivery vehicles, and ultra-precise dosing of high potency drugs. Here we demonstrate the use of solvent-free organic vapor jet printing to deposit nanostructured films of small molecular pharmaceutical ingredients, including caffeine, paracetamol, ibuprofen, tamoxifen, BAY 11-7082 and fluorescein, with accuracy on the scale of micrograms per square centimeter, onto glass, Tegaderm, Listerine tabs, and stainless steel microneedles...
September 27, 2017: Nature Communications
Harshul Thakkar, Stephen Eastman, Qasim Al-Naddaf, Ali A Rownaghi, Fateme Rezaei
Metal-organic frameworks (MOFs) have shown promising performance in separation, adsorption, reaction, and storage of various industrial gases; however, their large-scale applications have been hampered by the lack of a proper strategy to formulate them into scalable gas-solid contactors. Herein, we report the fabrication of MOF monoliths using the 3D printing technique and evaluation of their adsorptive performance in CO2 removal from air. The 3D-printed MOF-74(Ni) and UTSA-16(Co) monoliths with MOF loadings as high as 80 and 85 wt %, respectively, were developed, and their physical and structural properties were characterized and compared with those of MOF powders...
October 3, 2017: ACS Applied Materials & Interfaces
Jinah Jang
Numerous microfabrication approaches have been developed to recapitulate morphologically and functionally organized tissue microarchitectures in vitro; however, the technical and operational limitations remain to be overcome. 3D printing technology facilitates the building of a construct containing biomaterials and cells in desired organizations and shapes that have physiologically relevant geometry, complexity, and micro-environmental cues. The selection of biomaterials for 3D printing is considered one of the most critical factors to achieve tissue function...
August 18, 2017: Bioengineering
Hee-Gyeong Yi, Hyungseok Lee, Dong-Woo Cho
Organ-on-a-chip engineering aims to create artificial living organs that mimic the complex and physiological responses of real organs, in order to test drugs by precisely manipulating the cells and their microenvironments. To achieve this, the artificial organs should to be microfabricated with an extracellular matrix (ECM) and various types of cells, and should recapitulate morphogenesis, cell differentiation, and functions according to the native organ. A promising strategy is 3D printing, which precisely controls the spatial distribution and layer-by-layer assembly of cells, ECMs, and other biomaterials...
January 25, 2017: Bioengineering
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