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organ printing

Anna Clebone, Barbara K Burian, Scott C Watkins, Jorge A Gálvez, Justin L Lockman, Eugenie S Heitmiller
Cognitive aids such as checklists are commonly used in modern operating rooms for routine processes, and the use of such aids may be even more important during critical events. The Quality and Safety Committee of the Society for Pediatric Anesthesia (SPA) has developed a set of critical-event checklists and cognitive aids designed for 3 purposes: (1) as a repository of the latest evidence-based and expert opinion-based information to guide response and management of critical events, (2) as a source of just-in-time information during critical events, and (3) as a method to facilitate a shared understanding of required actions among team members during a critical event...
January 10, 2017: Anesthesia and Analgesia
Emanuela Cristina Freitas, Liane Biehl Printes, Odete Rocha
The specificity of cholinesterase (ChE) activity to detect the presence of anatoxin-a(s) and sublethal effects of a 7-day exposure to Anabaena spiroides extract containing anatoxin-a(s) were assessed in two freshwater cladoceran species. Activities of ChE of both Pseudosida ramosa and Daphnia magna can be used to indicate the presence of the neurotoxin anatoxin-a(s), but not for the hepatotoxic microcystin. Activity of ChE of P. ramosa, however, performed better as a biomarker of exposure to A. spiroides than that of D...
May 2016: Harmful Algae
Mohamad M Saab, Margaret Landers, Josephine Hegarty
PURPOSE: Men's awareness of testicular disorders is lacking and their intention to seek help for testicular symptoms is sub-optimal. Studies conducted to explore and raise men's awareness of testicular disorders did not address their preferred learning strategies and failed to include men who are at risk for health inequities. The aim of this study was to explore, in-depth, the preferred strategies for learning about testicular disorders inclusive of testicular cancer among men who self-identify as heterosexual, gay, or bisexual...
February 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
Kristina Lindsley, Jason J Nichols, Kay Dickersin
BACKGROUND: A hordeolum is a common, painful inflammation of the eyelid margin that is usually caused by a bacterial infection. The infection affects oil glands of the eyelid and can be either internal or external. In many cases, the lesion drains spontaneously and resolves without treatment; however, the inflammation can spread to other ocular glands or tissues, and recurrences are common. If unresolved, an acute internal hordeolum can become chronic, or can develop into a chalazion...
January 9, 2017: Cochrane Database of Systematic Reviews
H Wang, J J Wang, Y L Jiang, S Q Tian, Z Ji, F X Guo, H T Sun, J H Fan, Y P Xu
Objective: To analyze the difference of dosimetric parameters between pre-plan and post-plan of (125)I radioactive seed implantation assisted by 3D printing individual non-coplanar template (3D printing template) for locally recurrent rectal cancer (LRRC). Methods: From February 2016 to April 2016, a total of 10 patients with locally recurrent rectal cancer received (125)I seeds implantation under CT guidance assisted by 3D printing template in Department of Radiation Oncology, Peking University Third Hospital...
December 20, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Jiankang He, Fangyuan Xu, Ruonan Dong, Baolin Guo, Dichen Li
Electrohydrodynamic 3D printing is a promising strategy to controllably fabricate hierarchical fibrous architectures that mimic the structural organizations of native extracellular matrix. However, most of the existing investigations are mainly based on viscous melted biopolymers which make it difficult to uniformly incorporate bioactive or functional nanobiomaterials into the printed microfibers for functionization. Here we investigated the feasibility of employing solution-based electrohydrodynamic 3D printing to fabricate microscale poly (ε-caprolactone) (PCL) scaffolds with multi-walled carbon nanotubes (MWCNTs)...
January 4, 2017: Biofabrication
J Jung, N Potter, T Suh, C Liu, B Lu
PURPOSE: Using secondary skin collimation (SSC) to protect the critical organ surrounding the tumors is always desirable for electron and/or ortho-voltage treatments. However, the time-consuming and labor-intensive fabrication processes of current method (manually fabricate the lead mask) restrict the general use of SSC. The aim of this study is to develop a new SSC fabrication method using 3D scanning and 3D printing technologies in order to largely decrease the human labor involvement and fabrication time, also improve the fabrication accuracy...
June 2016: Medical Physics
Y Liao, H Chen, J Chen, X Gu, X Zhen, L Zhou
PURPOSE: To design and construct a three-dimensional (3D) anthropopathic abdominal phantom for evaluating deformable image registration (DIR) accuracy on images and dose deformation in adaptive radiation therapy (ART). METHOD: Organ moulds, including liver, kidney, spleen, stomach, vertebra and two metastasis tumors, are 3D printed using the contours from an ovarian cancer patient. The organ moulds are molded with deformable gels that made of different mixtures of polyvinyl chloride (PVC) and the softener dioctyl terephthalate...
June 2016: Medical Physics
K Albanese, R Morris, J Spencer, J Greenberg, A Kapadia
PURPOSE: Previously we reported the development of anthropomorphic tissue-equivalent scatter phantoms of the human breast. Here we present the first results from the scatter imaging of the tissue equivalent breast phantoms for breast cancer diagnosis. METHODS: A breast phantom was designed to assess the capability of coded aperture coherent x-ray scatter imaging to classify different types of breast tissue (adipose, fibroglandular, tumor). The phantom geometry was obtained from a prone breast geometry scanned on a dedicated breast CT system...
June 2016: Medical Physics
J Kim, E Myers, M Forbes, I Chetty, C Glide-Hurst
PURPOSE: As we move toward MR-only treatment planning, a need exists to develop multi-modality phantoms to benchmark synthetic CT (synCT) generation. We evaluated candidate materials for CT/MR compatible 3D printed phantoms to support MR-only planning. METHODS: Overall, 14 different 3D printing molding thermoplastic and UV photopolymer products were evaluated. Product samples (5.35 cm diameter disks) were obtained of urethane and silicone products of varying durometer: ClearFlex (50 and 95), Task 12, Smooth-Cast (45D, 60-61D), ReoFlex (20 through 60), VytaFlex 10, Flex Foam-iT! 17 urethane products as well as DragonSkin 10 and SORTA-Clear 18 silicone rubbers...
June 2016: Medical Physics
S Lee, M Kim, M Lee, T Suh
PURPOSE: The novel 3 dimensional (3D)-printed spine quality assurance (QA) phantoms generated by two different 3D-printing technologies, digital light processing (DLP) and Polyjet, were developed and evaluated for spine stereotactic body radiation treatment (SBRT). METHODS: The developed 3D-printed spine QA phantom consisted of an acrylic body and a 3D-printed spine phantom. DLP and Polyjet 3D printers using the high-density acrylic polymer were employed to produce spine-shaped phantoms based on CT images...
June 2016: Medical Physics
Silvia Marinozzi, Matteo Gulino, Valentina Gazzaniga
During the nineteenth century, the scientific context of rabies treatment was weak due to the lack of the literature on specific nosology of the rabies disease, and unspecific and ineffective therapy approaches. Electrotherapy already represented an important therapeutic approach for nervous system diseases, although not specifically for rabies. In the present paper, the authors discuss the use of electrotherapy in the treatment of humans affected by rabies in an experimental study conducted at the Maggiore Hospital of Milan, with the aim of establishing the discovery of a possible specific therapy...
December 2016: Acta Medico-historica Adriatica: AMHA
Yao Meng, Bingtao Tang, Benzhi Ju, Suli Wu, Shufen Zhang
Distinguished from the chromatic mechanism of dyes and pigments, structural color is derived from physical interactions of visible light with structures that are periodic at the scale of the wavelength of light. Using colloidal crystals with coloring functions for fabrics has resulted in significant improvements compared with chemical colors because the structural color from colloidal crystals bears many unique and fascinating optical properties, such as vivid iridescence and non-photobleaching. However, the poor mechanical performance of the structural color films cannot meet actual requirements because of the weak point contact of colloidal crystal particles...
December 29, 2016: ACS Applied Materials & Interfaces
Sytze J Buwalda, Tina Vermonden, Wim E Hennink
Hydrogels are attractive materials for the controlled release of therapeutics because of their capacity to embed biologically active agents in their water-swollen network. Recent advances in organic and polymer chemistry, bio-engineering and nanotechnology have resulted in several new developments in the field of hydrogels for therapeutic delivery. In this Perspective, we present our view on the state-of-the-art in the field, thereby focusing on a number of exciting topics, including bioorthogonal crosslinking methods, multi-component hydrogels, stimuli-responsive hydrogels, nanogels and the release of therapeutics from 3D printed hydrogels...
December 27, 2016: Biomacromolecules
Honglie Song, Junqiu Zhang, Daobing Chen, Kejun Wang, Shichao Niu, Zhiwu Han, Luquan Ren
Functional electronics has promising applications, including highly advanced human-interactive devices and healthcare monitoring. Here, we present a unique printable micron-scale cracked strain sensor (PMSCSS), which is bioinspired by a spider's crack-shaped lyriform slit organ. The PMSCSS is fabricated by a facile process that utilizes screen-printing to coat carbon black (CB) ink onto a paper substrate. With a certain bending radius, a cracked morphology emerged on the solidified ink layer. The working principle of the PMSCSS is prominently attributed to the strain-dependent variation in resistance due to the reconnection-disconnection of the crack fracture surfaces...
December 23, 2016: Nanoscale
Yunnan Fang, Jimmy G D Hester, Wenjing Su, Justin H Chow, Suresh K Sitaraman, Manos M Tentzeris
A bio-enabled, environmentally-friendly, and maximally mild layer-by-layer approach has been developed to surface modify inherently hydrophobic Kapton HN substrates to allow for great printability of both water- and organic solvent-based inks thus facilitating the full-inkjet-printing of flexible electronic devices. Different from the traditional Kapton surface modification approaches which are structure-compromising and use harsh conditions to target, and oxidize and/or remove part of, the surface polyimide of Kapton, the present Kapton surface modification approach targeted the surface electric charges borne by its additive particles, and was not only the first to utilize environmentally-friendly clinical biomolecules to build up a thin film of protamine-heparin complex on Kapton, but also the first to be conducted under minimally destructive and maximally mild conditions...
December 23, 2016: Scientific Reports
Heide-Katharina Bauer, Martin Heller, Matthias Fink, Daniela Maresch, Johannes Gartner, Ulrich M Gassner, Bilal Al-Nawas
The beginnings of three-dimensional (3D) printing and bioprinting can be traced to as early as 1984. From printing inorganic models for the generation of biologic scaffolds, additive manufacturing (AM) developed to the direct printing of organic materials, including specialized tissues, proteins, and cells. In recent years, these technologies have gained significantly in relevance, and there have been several innovations, especially in the field of regenerative medicine. It is becoming increasingly important to consider the economic and social aspects of AM, particularly in education and information of medical human resources, society, and politics, as well as for the establishment of homogenous, globally adapted legal regulations...
2016: International Journal of Computerized Dentistry
Qiaoming Zhang, Francesca Leonardi, Stefano Casalini, Inés Temiño, Marta Mas-Torrent
Since the first demonstration, the electrolyte-gated organic field-effect transistors (EGOFETs) have immediately gained much attention for the development of cutting-edge technology and they are expected to have a strong impact in the field of (bio-)sensors. However EGOFETs directly expose their active material towards the aqueous media, hence a limited library of organic semiconductors is actually suitable. By using two mostly unexplored strategies in EGOFETs such as blended materials together with a printing technique, we have successfully widened this library...
December 22, 2016: Scientific Reports
Marcin Kielar, Olivier Dhez, Gilles Pecastaings, Arnaud Curutchet, Lionel Hirsch
Printed organic photodetectors can transform plastic, paper or glass into smart surfaces. This innovative technology is now growing exponentially due to the strong demand in human-machine interfaces. To date, only niche markets are targeted since organic sensors still present reduced performances in comparison with their inorganic counterparts. Here we demonstrate that it is possible to engineer a state-of-the-art organic photodetector approaching the performances of Si-based photodiodes in terms of dark current, responsivity and detectivity...
December 22, 2016: Scientific Reports
Stephen Galas, Lenora L Copper
PURPOSE: To evaluate the individual contributions of pigment colorant and packing solution containing polyvinyl pyrrolidone (PVP) on the oxygen permeability (Dk) of a cosmetic printed etafilcon A daily disposable contact lens packaged with PVP. METHOD: The oxygen transport of a contact lens is evaluated through the central optical zone of the lens. Cosmetic printed contact lenses contain pigment colorant in the periphery or mid-periphery of the lens. Therefore, to assess the impact of cosmetic print on oxygen permeability, special lenses need to be produced that contain the colorant within the central optical zone...
2016: Clinical Ophthalmology
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