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https://www.readbyqxmd.com/read/28323640/a-micro-scale-printable-nanoclip-for-electrical-stimulation-and-recording-in-small-nerves
#1
Charles A Lissandrello, Winthrop F Gillis, Jun Shen, Ben W Pearre, Flavia Vitale, Matteo Pasquali, Bradley J Holinski, Daniel J Chew, Alice E White, Timothy J Gardner
OBJECTIVE: The vision of bioelectronic medicine is to treat disease by modulating the signaling of visceral nerves near various end organs. In small animal models, the nerves of interest can have small diameters and limited surgical access. New high-resolution methods for building nerve interfaces are desirable. In this study, we present a novel nerve interface and demonstrate its use for stimulation and recording in small nerves. APPROACH: We design and fabricate micro-scale electrode-laden nanoclips capable of interfacing with nerves as small as 50 µm in diameter...
March 21, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28319372/3d-printed-micrometre-scale-polymer-mounts-for-single-crystal-analysis
#2
Niall P Macdonald, Grace L Bunton, Ah Young Park, Michael C Breadmore, Nathan Laird Kilah
3D printed micrometre-scale polymer mounts for single crystal analysis have been prepared by photo polymerization using digital light projection stereolithography (DLP-SLA), with a commercially available digital light projection stereolithography printer (US$4000) and 3DM-ABS resin (US$150 per litre). The polymer mounts were prepared in batches of 49 in 1 hour 15 minutes, which allowed for rapid prototyping and testing of new crystal mounting designs, with a resin cost of 0.2¢ US per mount. The suitability of the 3D printed mounts for single crystal crystallography has been demonstrated through their use in Cu Kα X-ray diffraction experiments of Rochelle salt (sodium potassium tartrate), the protein lysozyme, and has been employed for routine crystallographic analysis of organic and inorganic materials...
March 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28319366/magnetic-printing-of-a-biosensor-inexpensive-rapid-sensing-to-detect-picomolar-amounts-of-antigen-with-antibody-functionalized-carbon-nanotubes
#3
Abdel Rahman Abdel Fattah, Ahmed M Abdalla, Sarah Mishriki, Elvira Meleca, Fei Geng, Suvojit Ghosh, Ishwar K Puri
When an antibody (Ab) is immobilized on its surface, a carbon nanotube (CNT) becomes a biosensor that detects the corresponding antigen (Ag) since Ag-Ab complexes formed on the CNT surface moderate the current flow through it. We synthesize a biological ink containing CNTs that are twice functionalized, first with magnetic nanoparticles (MNPs) and thereafter with the anti-c-Myc monoclonal Ab. The ink is pipetted and dynamically self organized by an external magnetic field into a dense electrically conducting sensor strip that measures the decrease in current when a sample containing c-Myc Ag is deposited on it...
March 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28319362/tuning-the-work-function-of-printed-polymer-electrodes-by-introducing-a-fluorinated-polymer-to-enhance-the-operational-stability-in-bottom-contact-organic-field-effect-transistors
#4
Se Hyun Kim, Jiye Kim, Sooji Nam, Hwa Sung Lee, Seung Woo Lee, Jaeyoung Jang
Poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS) is a promising electrode material for organic electronic devices due to its high conductivity, good mechanical flexibility, and feasibility of easy patterning with various printing methods. The work function of PEDOT:PSS needs to be increased for efficient hole injection and the addition of a fluorine-containing material has been reported to increase the work function of PEDOT:PSS. However, it remains a challenge to print PEDOT:PSS electrodes while simultaneously tuning their work functions...
March 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28317122/an-anthropomorphic-abdominal-phantom-for-deformable-image-registration-accuracy-validation-in-adaptive-radiation-therapy
#5
Yuliang Liao, Linjing Wang, Xiangdong Xu, Haibin Chen, Jiawei Chen, Guoqian Zhang, Huaiyu Lei, Ruihao Wang, Shuxu Zhang, Xuejun Gu, Xin Zhen, Linghong Zhou
PURPOSE: To design and construct a three-dimensional (3D) anthropomorphic abdominal phantom for geometric accuracy and dose summation accuracy evaluations of deformable image registration (DIR) algorithms for adaptive radiation therapy (ART). METHOD: Organ molds, including liver, kidney, spleen, stomach, vertebra and two metastasis tumors, were 3D printed using contours from an ovarian cancer patient. The organ molds were molded with deformable gels made of different mixtures of polyvinyl chloride (PVC) and the softener dioctyl terephthalate...
March 20, 2017: Medical Physics
https://www.readbyqxmd.com/read/28299927/supramolecular-hydrogels-based-on-dna-self-assembly
#6
Yu Shao, Haoyang Jia, Tianyang Cao, Dongsheng Liu
Extracellular matrix (ECM) provides essential supports three dimensionally to the cells in living organs, including mechanical support and signal, nutrition, oxygen, and waste transportation. Thus, using hydrogels to mimic its function has attracted much attention in recent years, especially in tissue engineering, cell biology, and drug screening. However, a hydrogel system that can merit all parameters of the natural ECM is still a challenge. In the past decade, deoxyribonucleic acid (DNA) has arisen as an outstanding building material for the hydrogels, as it has unique properties compared to most synthetic or natural polymers, such as sequence designability, precise recognition, structural rigidity, and minimal toxicity...
March 16, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28297682/degradation-of-organic-pollutants-by-bio-inspired-rectangular-and-hexagonal-titanium-dioxide-nanostructures
#7
T V M Sreekanth, Jae-Jin Shim, Yong Rok Lee
Dyes are used in textile, printing, leather, pharmaceutical, food and cosmetic industries. Dyes add color and pattern to materials. The presence of even very low concentration of dyes/dyes degradation products in effluent is highly toxic to humans and aquatic organisms. It is important to remove these dye degradation pollutants from the industrial effluents before their disposal. In recent years nanoparticles have been used for the removal of dyes from industrial waste water. Titanium dioxide nanostructures (TiO2 NS) were synthesized via a one-step facile green process...
March 9, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28291612/additive-or-non-additive-effect-of-mixing-oak-in-pine-stands-on-soil-properties-depends-on-the-tree-species-in-mediterranean-forests
#8
Caroline Brunel, Raphael Gros, Fabio Ziarelli, Anne Marie Farnet Da Silva
This study investigated how oak abundance in pine stands (using relative Oak Basal Area %, OBA%) may modulate soil microbial functioning. Forests were composed of sclerophyllous species i.e. Quercus ilex mixed with Pinus halepensis Miller or of Q. pubescens mixed with P. sylvestris. We used a series of plots with OBA% ranging from 0 to 100% in the two types of stand (n=60) and both OLF and A-horizon compartments were analysed. Relations between OBA% and either soil chemical (C and N contents, quality of organic matter via solid-state NMR, pH, CaCO3) or microbial (enzyme activities, basal respiration, biomass and catabolic diversity via BIOLOG) characteristics were described...
March 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28286520/acetylcholinesterase-inhibitors-assay-using-colorimetric-ph-sensitive-strips-and-image-analysis-by-a-smartphone
#9
Adam Kostelnik, Alexander Cegan, Miroslav Pohanka
Smartphones are widely spread and their usage does not require any trained personnel. Recently, smartphones were successfully used in analytical chemistry as a simple detection tool in some applications. This paper focuses on immobilization of acetylcholinesterase (AChE) onto commercially available pH strips with stabilization in the gelatin membrane. AChE degrades acetylcholine into choline and acetic acid which causes color change of acid-base indicator. Smartphone served as a tool for measurement of indicator color change from red to orange while inhibitors blocked this process...
2017: International Journal of Analytical Chemistry
https://www.readbyqxmd.com/read/28285531/copper-contamination-of-self-assembled-organic-monolayer-modified-silicon-surfaces-following-a-click-reaction-characterized-with-laps-and-spim
#10
Fan Wu, Dewen Zhang, Jian Wang, Michael Watkinson, Steffi Krause
A copper(I) catalyzed azide alkyne cycloaddition (CuAAC) reaction, combined with microcontact printing was employed successfully to pattern alkyne terminated self-assembled organic monolayer modified silicon surfaces. Despite the absence of a copper peak in X-ray photoelectron spectra (XPS), copper contamination was found and visualized using light-addressable potentiometric sensors (LAPS) and scanning photo-induced impedance microscopy (SPIM) after the 'click' modified silicon surfaces were rinsed with hydrochloric acid (HCl) solution, which has been frequently used to remove copper residues in the past...
March 13, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28282850/fully-printed-flexible-single-chip-rfid-tag-with-light-detection-capabilities
#11
Aniello Falco, Jose F Salmerón, Florin C Loghin, Paolo Lugli, Almudena Rivadeneyra
A printed passive radiofrequency identification (RFID) tag in the ultra-high frequency band for light and temperature monitoring is presented. The whole tag has been manufactured by printing techniques on a flexible substrate. Antenna and interconnects are realized with silver nanoparticles via inkjet printing. A sprayed photodetector performs the light monitoring, whereas temperature measurement comes from an in-built sensor in the silicon RFID chip. One of the advantages of this system is the digital read-out and transmission of the sensors information on the RFID tag that ensures reliability...
March 8, 2017: Sensors
https://www.readbyqxmd.com/read/28281114/value-of-3d-printing-for-the-comprehension-of-surgical-anatomy
#12
Stefania Marconi, Luigi Pugliese, Marta Botti, Andrea Peri, Emma Cavazzi, Saverio Latteri, Ferdinando Auricchio, Andrea Pietrabissa
BACKGROUND: In a preliminary experience, we claimed the potential value of 3D printing technology for pre-operative counseling and surgical planning. However, no objective analysis has ever assessed its additional benefit in transferring anatomical information from radiology to final users. We decided to validate the pre-operative use of 3D-printed anatomical models in patients with solid organs' diseases as a new tool to deliver morphological information. METHODS: Fifteen patients scheduled for laparoscopic splenectomy, nephrectomy, or pancreatectomy were selected and, for each, a full-size 3D virtual anatomical object was reconstructed from a contrast-enhanced MDCT (Multiple Detector Computed Tomography) and then prototyped using a 3D printer...
March 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28277649/development-of-liver-decellularized-extracellular-matrix-bioink-for-3d-cell-printing-based-liver-tissue-engineering
#13
Hyungseok Lee, Wonil Han, Hyeonji Kim, Dong-Heon Ha, Jinah Jang, Byoung Soo Kim, Dong-Woo Cho
The liver is an important organ and plays major roles in the human body. Due to the lack of liver donors after liver failure and drug-induced liver injury, much research has focused on developing liver alternatives and liver in vitro models for transplantation and drug screening. Although numerous studies have been conducted, these systems cannot faithfully mimic the complexity of the liver. Recently, three-dimensional (3D) cell printing technology has emerged as one of a number of innovative technologies that may help to overcome this limitation...
March 9, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28275737/programmable-and-coherent-crystallization-of-semiconductors
#14
Liyang Yu, Muhammad R Niazi, Guy O Ngongang Ndjawa, Ruipeng Li, Ahmad R Kirmani, Rahim Munir, Ahmed H Balawi, Frédéric Laquai, Aram Amassian
The functional properties and technological utility of polycrystalline materials are largely determined by the structure, geometry, and spatial distribution of their multitude of crystals. However, crystallization is seeded through stochastic and incoherent nucleation events, limiting the ability to control or pattern the microstructure, texture, and functional properties of polycrystalline materials. We present a universal approach that can program the microstructure of materials through the coherent seeding of otherwise stochastic homogeneous nucleation events...
March 2017: Science Advances
https://www.readbyqxmd.com/read/28255708/revealing-the-role-of-microscale-architecture-in-immune-synapse-function-through-surface-micropatterning
#15
Joung-Hyun Lee, Lance C Kam
The immune synapse has emerged as a compelling example of structural complexity within cell-cell interfaces. This chapter focuses on the use of microcontact printing to isolate and investigate how spatial organization of signaling molecules drives the function of immune cells. In the process detailed here, multiple rounds of microcontact printing are combined to create patterned surfaces that control the relative spatial localization of CD3 and CD28 signaling in T cells, effectively replacing an antigen presenting cell with an engineered surface...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28255127/-progress-in-application-of-3d-bioprinting-in-cartilage-regeneration-and-reconstruction-for-tissue-engineering
#16
Junlin Liao, Shaohua Wang, Jia Chen, Hongju Xie, Jianda Zhou
Three-dimensional (3D) bioprinting provides an advanced technology for tissue engineering and regenerative medicine because of its ability to produce the models or organs with higher precision and more suitable for human body. It has been successfully used to produce a variety of cartilage scaffold materials. In addition, 3D bioprinter can directly to print tissue and organs with live chondrocytes. In conclusion, 3D bioprinting may have broad prospect for cartilage regeneration and reconstruction in tissue engineering...
February 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28249472/rapid-jetting-status-inspection-and-accurate-droplet-volume-measurement-for-a-piezo-drop-on-demand-inkjet-print-head-using-a-scanning-mirror-for-display-applications
#17
Dong-Youn Shin, Minsung Kim
Despite the inherent fabrication simplicity of piezo drop-on-demand inkjet printing, the non-uniform deposition of colourants or electroluminescent organic materials leads to faulty display products, and hence, the importance of rapid jetting status inspection and accurate droplet volume measurement increases from a process perspective. In this work, various jetting status inspections and droplet volume measurement methods are reviewed by discussing their advantages and disadvantages, and then, the opportunities for the developed prototype with a scanning mirror are explored...
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28239008/health-ministry-and-activities-in-african-american-faith-based-organizations-a-qualitative-examination-of-facilitators-barriers-and-use-of-technology
#18
Cheryl L Holt, Anita L Graham-Phillips, C Daniel Mullins, Jimmie L Slade, Alma Savoy, Roxanne Carter
African American faith-based organizations (FBOs) play an important role in addressing health disparities. Increasingly, churches offer health fairs, screenings, or education through health ministries. However, little is known about linking these organizations with evidence-based interventions (EBIs) developed by research. This study explored 1) factors that facilitate or impede health ministry activities, including the adoption of EBIs, and 2) opportunities to use technology to support/enhance the capacity of FBOs to sustain health-related activities...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28228002/custom-shaped-organic-photovoltaic-modules-freedom-of-design-by-printing
#19
M Välimäki, E Jansson, P Korhonen, A Peltoniemi, S Rousu
Freedom of design that was introduced as organic photovoltaic (OPV) modules were fabricated by printing. As proof-of-concept, we show OPV leaf fabrication in A5 size using gravure and rotary screen printing processes for the main active layers of the OPV structure. These printing methods allow direct printing of any kind of arbitrary, two-dimensional shapes including patterning of the electric contacts thus post-patterning stages are not needed. Fabrication of custom-shaped OPV modules requires detailed information about the technical boundaries set by the manufacturing process and materials which in turn influence the layout design and R2R upscaling...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28225616/a-straightforward-approach-for-3d-bacterial-printing
#20
Benjamin A E Lehner, Dominik T Schmieden, Anne S Meyer
Sustainable and personally tailored materials production is an emerging challenge to society. Living organisms can produce and pattern an extraordinarily wide range of different molecules in a sustainable way. These natural systems offer an abundant source of inspiration for the development of new environmentally friendly materials production techniques. In this paper, we describe the first steps toward the 3-dimensional printing of bacterial cultures for materials production and patterning. This methodology combines the capability of bacteria to form new materials with the reproducibility and tailored approach of 3D printing systems...
March 1, 2017: ACS Synthetic Biology
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