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https://www.readbyqxmd.com/read/29225769/fabrication-of-low-cost-micropatterned-polydimethyl-siloxane-scaffolds-to-organise-cells-in-a-variety-of-two-dimensioanl-biomimetic-arrangements-for-lab-on-chip-culture-platforms
#1
Lidia Escutia-Guadarrama, Genaro Vázquez-Victorio, David Martínez-Pastor, Brenda Nieto-Rivera, Marcela Sosa-Garrocho, Marina Macías-Silva, Mathieu Hautefeuille
We present the rapid-prototyping of type I collagen micropatterns on poly-dimethylsiloxane substrates for the biomimetic confinement of cells using the combination of a surface oxidation treatment and 3-aminopropyl triethoxysilane silanisation followed by glutaraldehyde crosslinking. The aim of surface treatment is to stabilise microcontact printing transfer of this natural extracellular matrix protein that usually wears out easily from poly-dimethylsiloxane, which is not suitable for biomimetic cell culture platforms and lab-on-chip applications...
January 2017: Journal of Tissue Engineering
https://www.readbyqxmd.com/read/29224259/-expert-consensus-of-precise-diagnosis-and-treatment-for-pancreatic-head-cancer-using-three-dimensional-visualization-technology
#2
(no author information available yet)
Three-dimensional (3D) visualization technology in pancreatic head cancers could offer decision-making support to preoperative diagnosis, resectability assessment and individualized surgical planning. In addition, the pancreas 3D printing helps to realize the leapfrog development from 3D images to 3D physical models and provides better guidance of the precise surgery of complicated cancers of the pancreatic head. In order to standardize the application of 3D visualization and 3D printing technology in the diagnosis and treatment of pancreatic head cancer, Chinese experts in relevant fields were organized by four committees to formulate this expert consensus...
December 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29223704/decellularized-heart-ecm-hydrogel-using-supercritical-carbon-dioxide-for-improved-angiogenesis
#3
Yoojin Seo, Youngmee Jung, Soo Hyun Kim
Initial angiogenesis within the first 3 days is critical for healing ischemic diseases such as myocardial infarction. Recently, decellularized extracellular matrix (dECM) has been reported to provide tissue-derived ECM components and can be used as a scaffold for cell delivery for angiogenesis in tissue engineering. Decellularization by various detergents such as sodium dodecyl sulfate (SDS) and triton X-100 can remove the cell nuclei in tissue organs. However, this leads to ECM structure denaturation, decreased presence of various ECM proteins and cytokines, and loss of mechanical properties...
December 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29221371/two-step-nanoscale-approach-for-well-defined-complex-alkanethiol-films-on-au-surfaces
#4
Shova Neupane, Patricia Losada-Pérez, Sebastien Vivegnis, Zineb Mekhalif, Joseph Delhalle, Asif Bashir, Frank Uwe U Renner
Controlling the molecular organization of organic self-assembled monolayers (SAM) is of utmost importance in nanotechnology, molecular electronics, and surface science. Here we propose two well-differentiated approaches, double printing based on microcontact printing (µ-cp) and molecular back-filling adsorption, to produce complex alkanethiol films. The resulting films on model Au surfaces were characterized by atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS) and contact angle measurements...
December 8, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29219301/high-performance-sub-micrometer-channel-wse2-field-effect-transistors-prepared-using-a-flood-dike-printing-method
#5
Fanqi Wu, Liang Chen, Anyi Zhang, Yi-Lun Hong, Nai-Yun Shih, Seong-Yong Cho, Gryphon A Drake, Tyler Fleetham, Sen Cong, Xuan Cao, Qingzhou Liu, Yihang Liu, Chi Xu, Yuqiang Ma, Moonsub Shim, Mark E Thompson, Wencai Ren, Hui-Ming Cheng, Chongwu Zhou
Printing technology has potential to offer a cost-effective and scalable way to fabricate electronic devices based on two-dimensional (2D) transition metal dichalcogenides (TMDCs). However, limited by the registration accuracy and resolution of printing, the previously reported printed TMDC field-effect transistors (FETs) have relatively long channel lengths (13-200 μm), thus suffering low current-driving capabilities (≤0.02 μA/μm). Here, we report a "flood-dike" self-aligned printing technique that allows the formation of source/drain metal contacts on TMDC materials with sub-micrometer channel lengths in a reliable way...
December 8, 2017: ACS Nano
https://www.readbyqxmd.com/read/29217956/utilization-status-of-electronic-information-sources-eis-for-hiv-aids-care-and-treatment-in-specialized-teaching-hospitals-of-ethiopia-2016
#6
Senait Samuel Bramo, Tesfamichael Alaro Agago
Background: According to the World Health Organization, the use of Electronic Information Sources (EIS) in healthcare is not merely about application of technology, but it is also a foundation to provide higher quality clinical care. This study was aimed to assess Utilization Status of EIS for HIV/AIDS Care and Treatment in specialized teaching hospitals of Ethiopia, 2016. Materials and Methods: A facility based cross-sectional study design was used. The study populations were 352 healthcare professionals selected by using simple random sampling technique from three randomly selected specialized teaching hospitals of Ethiopia...
September 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29203812/a-highly-printable-and-biocompatible-hydrogel-composite-for-direct-printing-of-soft-and-perfusable-vasculature-like-structures
#7
Ratima Suntornnond, Edgar Yong Sheng Tan, Jia An, Chee Kai Chua
Vascularization is one major obstacle in bioprinting and tissue engineering. In order to create thick tissues or organs that can function like original body parts, the presence of a perfusable vascular system is essential. However, it is challenging to bioprint a hydrogel-based three-dimensional vasculature-like structure in a single step. In this paper, we report a new hydrogel-based composite that offers impressive printability, shape integrity, and biocompatibility for 3D bioprinting of a perfusable complex vasculature-like structure...
December 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29200264/fully-coated-semitransparent-organic-solar-cells-with-a-doctor-blade-coated-composite-anode-buffer-layer-of-phosphomolybdic-acid-and-pedot-pss-and-a-spray-coated-silver-nanowire-top-electrode
#8
J I Guoqi, Yiying Wang, Qun Luo, Kang Han, Menglan Xie, Lianping Zhang, Na Wu, Jian Lin, Shugang Xiao, Yanqing Li, Liqiang Luo, Chang-Qi Ma
Aiming to realize high performance semitransparent fully coated organic solar cells, printable electrode buffer layers and top electrodes are two important key technologies. An ideal ink for the preparation of the electrode buffer layer for printed top electrodes should have good wettability and negligible solvent corrosion to the underlying layer. This work reports a novel organic-inorganic composite of phosphomolybdic acid (PMA) and PEDOT:PSS that features excellent wettability with the active layer and printed top Ag nanowires, and high resistibility to solvent corrosion...
December 4, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29197301/dispensing-based-bioprinting-of-mechanically-functional-hybrid-scaffolds-with-vessel-like-channels-for-tissue-engineering-applications-a-brief-review
#9
REVIEW
Saman Naghieh, Md Sarker, Mohammad Izadifar, Xiongbiao Chen
Over the past decades, significant progress has been achieved in the field of tissue engineering (TE) to restore/repair damaged tissues or organs and, in this regard, scaffolds made from biomaterials have played a critical role. Notably, recent advances in biomaterials and three-dimensional (3D) printing have enabled the manipulation of two or more biomaterials of distinct, yet complementary, mechanical and/or biological properties to form so-called hybrid scaffolds mimicking native tissues. Among various biomaterials, hydrogels synthesized to incorporate living cells and/or biological molecules have dominated due to their hydrated tissue-like environment...
November 26, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29193879/organ-bioprinting-are-we-there-yet
#10
REVIEW
Guifang Gao, Ying Huang, Arndt F Schilling, Karen Hubbell, Xiaofeng Cui
About 15 years ago, bioprinting was coined as one of the ultimate solutions to engineer vascularized tissues, which was impossible to accomplish using the conventional tissue fabrication approaches. With the advances of 3D-printing technology during the past decades, one may expect 3D bioprinting being developed as much as 3D printing. Unfortunately, this is not the case. The printing principles of bioprinting are dramatically different from those applied in industrialized 3D printing, as they have to take the living components into account...
November 29, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29189088/intra-and-interpersonal-effects-of-coping-on-the-psychological-well-being-of-adults-with-sensory-loss-and-their-spouses
#11
Christine M Lehane, Jesper Dammeyer, Walter Wittich
PURPOSE: The aim of the current study was to examine the associations between coping and psychological well-being among adults with sensory loss and their spouses. METHODS: A total of 183 adults with sensory loss and 133 spouses participated in an online survey and were followed up six months later. Coping and well-being were measured using the Brief Coping Orientation to Problems Experienced Scale (Brief COPE) and the five-item World Health Organization Well-Being Index (WHO-5), respectively...
November 30, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29186669/high-capacity-redox-polymer-electrodes-applications-in-molecular-and-cellular-processing
#12
Craig Galligan, Christopher Nguyen, John Nelson, Patrick Spooner, Todd Miller, Brian M Davis, Ralf Lenigk, Christopher M Puleo
We present methods to fabricate high-capacity redox electrodes using thick membrane or fiber casting of conjugated polymer solutions. Unlike common solution casting or printing methods used in current organic electronics, the presented techniques enable production of PEDOT:PSS electrodes with high charge capacity and the capability to operate under applied voltages greater than 100 V without electrochemical overoxidation. The electrodes are shown integrated into several electrokinetic components commonly used in automated bioprocess or bioassay workflows, including electrophoretic DNA separation and extraction, cellular electroporation/lysis, and electroosmotic pumping...
November 1, 2017: SLAS Technology
https://www.readbyqxmd.com/read/29182800/interventions-to-increase-tuberculosis-case-detection-at-primary-healthcare-or-community-level-services
#13
REVIEW
Francis A Mhimbira, Luis E Cuevas, Russell Dacombe, Abdallah Mkopi, David Sinclair
BACKGROUND: Pulmonary tuberculosis is usually diagnosed when symptomatic individuals seek care at healthcare facilities, and healthcare workers have a minimal role in promoting the health-seeking behaviour. However, some policy specialists believe the healthcare system could be more active in tuberculosis diagnosis to increase tuberculosis case detection. OBJECTIVES: To evaluate the effectiveness of different strategies to increase tuberculosis case detection through improving access (geographical, financial, educational) to tuberculosis diagnosis at primary healthcare or community-level services...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29178351/printing-semiconductor-insulator-polymer-bilayers-for-high-performance-coplanar-field-effect-transistors
#14
Laju Bu, Mengxing Hu, Wanlong Lu, Ziyu Wang, Guanghao Lu
Source-semiconductor-drain coplanar transistors with an organic semiconductor layer located within the same plane of source/drain electrodes are attractive for next-generation electronics, because they could be used to reduce material consumption, minimize parasitic leakage current, avoid cross-talk among different devices, and simplify the fabrication process of circuits. Here, a one-step, drop-casting-like printing method to realize a coplanar transistor using a model semiconductor/insulator [poly(3-hexylthiophene) (P3HT)/polystyrene (PS)] blend is developed...
November 27, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29176055/multiscale-assembly-of-solution-processed-organic-electronics-the-critical-roles-of-confinement-fluid-flow-and-interfaces
#15
Bijal Bankim Patel, Ying Diao
Organic semiconducting small molecules and polymers provide a rich phase space for investigating the fundamentals of molecular and hierarchical assembly. Stemming from weak intermolecular interactions, their assembly sensitively depends on processing conditions, which in turn drastically modulate their electronic properties. Much work has gone into molecular design strategies that maximize intermolecular interactions and encourage close packing. Less understood, however, is the nonequilibrium assembly that occurs during the fabrication process (especially solution coating and printing) which is critical to determining thin film morphology across length scales...
November 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29174261/know-thy-neighbors-the-status-of-cardiac-surgery-in-the-south-asian-countries-around-india
#16
REVIEW
Nazmul Hosain, Farzana Amin, Somaiya Rehman, Bhagawan Koirala
OBJECTIVES: The South Asian neighboring countries of India include Bangladesh, Bhutan, Nepal, The Maldives, Pakistan and Sri Lanka. Interestingly all these countries possess either a land or a sea border with India and no border among themselves. These countries have historic, cultural, ethnic and genetic links with India. The paper describes the developmental history and current status of cardiac surgery in these countries. METHODS: Thorough search of the printed and electronic materials has been made...
November 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29172145/a-novel-3d-bioprinted-flexible-and-biocompatible-hydrogel-bioelectronic-platform
#17
Shweta Agarwala, Jia Min Lee, Wei Long Ng, Michael Layani, Wai Yee Yeong, Shlomo Magdassi
Bioelectronics platforms are gaining widespread attention as they provide a template to study the interactions between biological species and electronics. Decoding the effect of the electrical signals on the cells and tissues holds the promise for treating the malignant tissue growth, regenerating organs and engineering new-age medical devices. This work is a step forward in this direction, where bio- and electronic materials co-exist on one platform without any need for post processing. We fabricate a freestanding and flexible hydrogel based platform using 3D bioprinting...
November 16, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29171457/tubercular-colitis-masquerading-as-ischemic-colitis-an-unusual-presentation
#18
Vishal Sharma, Harshal S Mandavdhare, Kaushal K Prasad, Harjeet Singh, Usha Dutta
Tuberculosis is a common clinical problem which can involve virtually any organ and mimic a multitude of clinical conditions. Colonic tuberculosis is a type of intestinal tuberculosis which involves the colon and mimics inflammatory bowel disease. Occasionally, it is also confused with colonic malignancy. We report the case of a young female who presented with abdominal pain, bleeding per rectum. Abdominal X-ray showed evidence of thumb-printing. A possibility of ischemic colitis was entertained. However, further investigation unraveled the presence of tubercular colitis...
October 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/29157561/-choosing-wisely-rationale-implementation-and-evaluation
#19
Gerd Hasenfuß, Ulrich R Fölsch
"Klug entscheiden" (Choosing Wisely) is an initiative launched by the German Society for Internal Medicine (DGIM) to boost the quality of medical indication by identifying both medical/therapeutic over- and underuse. Twelve specialist societies for internal medicine and DGIM associated societies develop corresponding recommendations which are subsequently evaluated and rejected or approved in a structured procedure by a multidisciplinary commission. Since 2016, 115 positive and negative recommendations have been developed and released for print media, radio and television...
November 17, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29155730/long-term-live-imaging-device-for-improved-experimental-manipulation-of-zebrafish-larvae
#20
Kayla Huemer, Jayne M Squirrell, Robert Swader, Kirsten Pelkey, Danny C LeBert, Anna Huttenlocher, Kevin W Eliceiri
The zebrafish larva is an important model organism for both developmental biology and wound healing. Further, the zebrafish larva is a valuable system for live high-resolution microscopic imaging of dynamic biological phenomena in space and time with cellular resolution. However, the traditional method of agarose encapsulation for live imaging can impede larval development and tissue regrowth. Therefore, this manuscript describes the zWEDGI (zebrafish Wounding and Entrapment Device for Growth and Imaging), which was designed and fabricated as a functionally compartmentalized device to orient larvae for high-resolution microscopy while permitting caudal fin transection within the device and subsequent unrestrained tail development and re-growth...
October 27, 2017: Journal of Visualized Experiments: JoVE
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