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https://www.readbyqxmd.com/read/28928151/comparative-analysis-reveals-genomic-features-of-stress-induced-transcriptional-readthrough
#1
Anna Vilborg, Niv Sabath, Yuval Wiesel, Jenny Nathans, Flonia Levy-Adam, Therese A Yario, Joan A Steitz, Reut Shalgi
Transcription is a highly regulated process, and stress-induced changes in gene transcription have been shown to play a major role in stress responses and adaptation. Genome-wide studies reveal prevalent transcription beyond known protein-coding gene loci, generating a variety of RNA classes, most of unknown function. One such class, termed downstream of gene-containing transcripts (DoGs), was reported to result from transcriptional readthrough upon osmotic stress in human cells. However, how widespread the readthrough phenomenon is, and what its causes and consequences are, remain elusive...
September 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28924412/adding-access-to-a-video-magnifier-to-standard-vision-rehabilitation-initial-results-on-reading-performance-and-well-being-from-a-prospective-randomized-study
#2
Mary Lou Jackson, Kimberly A Schoessow, Alexandra Selivanova, Jennifer Wallis
PURPOSE: Both optical and electronic magnification are available to patients with low vision. Electronic video magnifiers are more expensive than optical magnifiers, but they offer additional benefits, including variable magnification and contrast. This study aimed to evaluate the effect of access to a video magnifier (VM) added to standard comprehensive vision rehabilitation (VR). METHODS: In this prospective study, 37 subjects with central field loss were randomized to receive standard VR (VR group, 18 subjects) or standard VR plus VM (VM group, 19 subjects)...
2017: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/28924051/the-stress-regulatory-transcription-factors-msn2-and-msn4-regulate-fatty-acid-oxidation-in-budding-yeast
#3
Praveen Kumar Rajvanshi, Madhuri Arya, Ram Rajasekharan
The transcription factors multicopy suppressor of SNF1 mutation (Msn) Msn2 and Msn4 bind the stress-response element in gene promoters in the yeast Saccharomyces cerevisiae. However, the roles of Msn2/4 in primary metabolic pathways such as fatty acid β-oxidation are unclear. Here, in silico analysis revealed that the promoters of most genes involved in the biogenesis, function, and regulation of the peroxisome contain Msn2/4 binding sites. We also found that transcript levels of MSN2/MSN4 are increased in glucose-depletion conditions and that during growth in nonpreferred carbon sources, Msn2 is constantly localized to the nucleus in wildtype cells...
September 18, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28915274/prevalence-of-mind-and-body-exercises-mbe-in-relation-to-demographics-self-rated-health-and-purchases-of-prescribed-psychotropic-drugs-and-analgesics
#4
Lina Rådmark, Linda L Magnusson Hanson, Eva Bojner Horwitz, Walter Osika
This study aims to identify any differences regarding gender, age, socioeconomic status (SES), self-rated health, perceived stress and the purchase of prescribed drugs among people who practice mind and body exercises (MBE) extensively compared to people who do not. METHODS: The study includes 3,913 men and 4,803 women aged 20-72 who participated in the Swedish Longitudinal Occupational Survey of Health (SLOSH). The respondents were divided into three groups depending on frequency of MBE practice (never/seldom/often)...
2017: PloS One
https://www.readbyqxmd.com/read/28914626/secondary-traumatic-stress-in-nicu-nurses-a-mixed-methods-study
#5
Cheryl Tatano Beck, Regina M Cusson, Robert K Gable
BACKGROUND: Secondary traumatic stress is an occupational hazard for healthcare providers who care for patients who have been traumatized. This type of stress has been reported in various specialties of nursing, but no study to date had specifically focused on neonatal intensive care unit (NICU) nurses. PURPOSE: (1) To determine the prevalence and severity of secondary traumatic stress in NICU nurses and (2) to explore those quantitative findings in more depth through nurses' qualitative descriptions of their traumatic experiences caring for critically ill infants in the NICU...
September 13, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28905809/the-acceptance-of-illness-in-lung-cancer-patients-before-and-after-surgical-treatment
#6
Andrzej Nowicki, Paulina Graczyk, Marzena Lemanowicz
Lung cancer is the most common malignant tumor in the world, as well as one of the cancers with the most fatal prognosis. The acceptance of the disease is the most important element of the adaptive process. The better the illness acceptance, the lower the stress level and the higher the self-esteem, which facilitates the adaptation to the health status. AIM: The aim of this study was to assess the acceptance of the disease in patients before and after lung cancer surgery. MATERIALS AND METHODS: The study was conducted in 2016 at the Center of Oncology in Bydgoszcz and the Kuyavian and Pomeranian Pulmonology Center in Bydgoszcz...
August 31, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28904912/assessment-of-anxiety-level-of-emergency-health-care-workers-by-generalized-anxiety-disorder-7-tool
#7
Nesrin Alharthy, Osama Abdulrahman Alrajeh, Mohammed Almutairi, Ahmed Alhajri
BACKGROUND: Dealing with emergency patients is considered to be a stressful situation to all health-care workers in the emergency department (ED). Prolonged stress predispose to physical and inconsequential psychiatric disturbances. Anxiety and depressive mode were found to be the most commonly experienced psychiatric manifestation among emergency health-care workers. The aim of this study is to screen and assess the severity of anxiety among health professionals working in ED. METHODS: Cross-sectional study design was used...
July 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28903356/sexual-life-satisfaction-and-its-associated-socio-demographic-and-workplace-factors-among-chinese-female-nurses-of-tertiary-general-hospitals
#8
Feng Ji, Deguo Jiang, Xiaodong Lin, Wei Zhang, Weifang Zheng, Ce Cheng, Chongguang Lin, Lirong Hu, Chuanjun Zhuo
Adverse workplace factors such as job stress are reported to be associated with poor physical and mental health of nurses. However, associations between occupational factors and sexual life satisfaction (SLS) of nurses remain understudied. This study investigated SLS of Chinese female nurses of tertiary general hospitals and socio-demographic and occupational factors associated with reduced SLS of nurses. In this cross-sectional survey, 393 Chinese female nurses of four tertiary general hospitals completed a standardized socio-demographic and occupational characteristics questionnaire, Zung's Self-rating Scale for Depression, Job Content Questionnaire, and a self-report SLS question...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28901205/satisfaction-burnout-and-turnover-among-nurse-practitioners-and-physician-assistants-a-review-of-the-empirical-literature
#9
Timothy Hoff, Shannon Carabetta, Grace E Collinson
Examining the work-related psychological states of nurse practitioners and physician assistants is important, given their increased role expansion. The current PRISMA-guided review examined studies published between 2000 and 2016 for both these groups. The review also examined features of the research to draw conclusions about overall quality. Applying theories in job enrichment and job demands, 32 articles were identified that contained analyses of satisfaction, burnout, stress, and turnover. Key findings include the lack of robust research designs, overemphasis on job satisfaction, lower levels of satisfaction across both groups, and higher intrinsic versus extrinsic satisfaction levels generally...
September 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/28900410/human-connections-and-their-roles-in-the-occupational-well-being-of-healthcare-professionals-a-study-on-loneliness-and-empathy
#10
Jorge Soler-Gonzalez, Montserrat San-Martín, Roberto Delgado-Bolton, Luis Vivanco
Human connections are key to the promotion of health and prevention of illness; moreover, illness can cause deterioration of human connections. Healthcare professional-patient relationships are key to ensuring the preservation of adequate human connections. It is important for healthcare professionals to develop their ability to foster satisfactory human connections because: (i) they represent social support for patients; and (ii) they prevent work-related stress. In this study we assessed the relationship between absence (loneliness) and presence (empathy) of human connections with the occupational well-being of healthcare professionals...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28898963/job-demands-resources-and-mental-health-in-uk-prison-officers
#11
G Kinman, A J Clements, J Hart
Background: Research findings indicate that working as a prison officer can be highly stressful, but the aspects of work that predict their mental health status are largely unknown. Aims: To examine, using elements of the demands-resources model, the extent to which work pressure and several potential resources (i.e. control, support from managers and co-workers, role clarity, effective working relationships and positive change management) predict mental health in a sample of UK prison officers...
August 1, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28898109/factors-associated-with-type-ii-trauma-in-occupational-groups-working-with-traumatised-children-a-systematic-review
#12
Clara A M Sage, Samantha K Brooks, Neil Greenberg
BACKGROUND: There is evidence that "Type II trauma" (TTT) - repeated exposure to traumatic events - can lead to the development of post-traumatic stress disorder (PTSD). TTT frequently occurs in occupational groups working with children who are themselves victims of trauma. AIM: To conduct a systematic review identifying risk factors for/protective factors against TTT-associated mental ill-health in employees working with traumatised children and explore how this type of work impacts upon social functioning...
September 12, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28895982/prevalence-of-and-risk-factors-for-low-back-pain-among-healthcare-workers-in-denizli
#13
Şule Şimşek, Nesrin Yağcı, Hande Şenol
OBJECTIVES: The purpose of this study was to examine personal, occupational, and psychosocial risk factors affecting prevalence of low back pain in healthcare workers. METHODS: Study included total of 1682 participants (1010 female, 672 male) working at Denizli State Hospital. Low back pain section of Standardized Nordic Musculoskeletal Questionnaire (SNMA) was used to evaluate recent occurrence, pain experienced within previous year, and over lifetime. Perceived Stress Scale and Job Satisfaction Scale were also administered...
April 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/28895899/effects-of-heat-stress-on-construction-labor-productivity-in-hong-kong-a-case-study-of-rebar-workers
#14
Wen Yi, Albert P C Chan
Global warming is bringing more frequent and severe heat waves, and the result will be serious for vulnerable populations such as construction workers. Excessive heat stress has profound effects on physiological responses, which cause occupational injuries, fatalities and low productivity. Construction workers are particularly affected by heat stress, because of the body heat production caused by physically demanding tasks, and hot and humid working conditions. Field studies were conducted between August and September 2016 at two construction training grounds in Hong Kong...
September 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28895434/genetic-variation-and-risk-of-dna-damage-in-peripheral-blood-lymphocytes-of-iranian-formaldehyde-exposed-workers
#15
Rezvan Zendehdel, Parviz Abdolmaleki, Fatemeh Javani Jouni, Mohammad Mazinani
Formaldehyde (FA) has given positive results for the genetic damage evaluated in human peripheral blood lymphocytes. Polymorphism plays a special role in the toxicity of chemicals. DNA damage in blood cells was evaluated in workers who were occupationally exposed to FA. This study tested the association of alcohol dehydrogenase III (ADH3) and manganese-superoxide dismutase (Mn-SOD) gene polymorphism, with DNA damage of peripheral blood lymphocytes. Gene polymorphisms were evaluated in 54 workers from melamine dinnerware workshops and 34 workers from dairy production workshops...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28890742/who-in-europe-works-beyond-the-state-pension-age-and-under-which-conditions-results-from-share
#16
Morten Wahrendorf, Bola Akinwale, Rebecca Landy, Katey Matthews, David Blane
There is much research about those who exit the labour market prematurely, however, comparatively little is known about people working longer and about their employment and working conditions. In this paper, we describe the employment and working conditions of men and women working between 65 and 80 years, and compare them with previous conditions of those retired in the same age group. Analyses are based on wave 4 data from the Survey of Health, Ageing and Retirement in Europe (SHARE) with information collected between 2009 and 2011 from 17,625 older men and women across 16 European countries...
2017: Journal of Population Ageing
https://www.readbyqxmd.com/read/28890281/participation-in-a-us-community-based-cardiovascular-health-study-investigating-nonrandom-selection-effects-related-to-employment-perceived-stress-work-related-stress-and-family-caregiving
#17
Leslie A MacDonald, Kaori Fujishiro, Virginia J Howard, Paul Landsbergis, Misty J Hein
PURPOSE: Participation in health studies may be inversely associated with employment and stress. We investigated whether employment, perceived stress, work-related stress, and family caregiving were related to participation in a longitudinal US community-based health study of black and white men and women aged ≥45 years. METHODS: Prevalence ratios and confidence intervals were estimated for completion of the second stage (S2) of a two-stage enrollment process by employment (status, type), and stress (perceived stress, work-related stress, caregiving), adjusting for age, sex, race, region, income, and education...
August 15, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28887796/enabling-work-occupational-therapy-interventions-for-persons-with-occupational-injuries-and-diseases-a-scoping-review
#18
REVIEW
Alexa Jane T Blas, Kenneth Matthew B Beltran, Pauline Gail V Martinez, Daryl Patrick G Yao
Purpose This review aims to map the scope of published research on occupational therapy (OT) interventions and pertinent work and work-related outcomes for persons with occupational injuries and diseases. Methods The scoping review adapted Arksey and O'Malley's framework. Six electronic databases were searched. Ancestral search was also done on five systematic reviews. The search was conducted from September 2015 to October 2015. Interventions and outcomes were coded using the International Classification of Functioning, Disability and Health Core Set for Vocational Rehabilitation to plot trends...
September 8, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28886136/relationship-between-the-number-of-family-members-and-stress-by-gender-cross-sectional-analysis-of-the-fifth-korea-national-health-and-nutrition-examination-survey
#19
Jin-Won Noh, Kyoung-Beom Kim, Jumin Park, Janghun Hong, Young Dae Kwon
BACKGROUND: Due to gendered inequalities in the division of domestic work, women with paid employment and family caregiving responsibilities can feel extremely tired with general distress and depression. Therefore, the purpose of this study was to examine the association between the number of family members and stress level by gender among Korean adults using a nationally representative dataset. METHODS: We used a sample of 6,293 subjects aged 19 or older (3,629 female and 2,264 male) from the fifth Korea National Health and Nutrition Examination Survey...
2017: PloS One
https://www.readbyqxmd.com/read/28878710/examining-depressive-symptoms-and-their-predictors-in-malaysia-stress-locus-of-control-and-occupation
#20
Si H Yeoh, Cai L Tam, Chee P Wong, Gregory Bonn
The 2015 National Health and Morbidity Survey estimated that over 29% of the adult population of Malaysia suffers from mental distress, a nearly 3-fold increase from the 10.7% estimated by the NHMS in 1996 pointing to the potential beginnings of a public health crisis. This study aimed to better understand this trend by assessing depressive symptoms and their correlates in a cross-section of Malaysians. Specifically, it assesses stress, perceived locus of control, and various socio-demographic variables as possible predictors of depressive symptoms in the Malaysian context...
2017: Frontiers in Psychology
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