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https://www.readbyqxmd.com/read/29339257/changes-in-the-concentrations-of-inflammatory-and-oxidative-status-biomediators-mip-1-%C3%AE-pmn-elastase-mda-and-il-12-in-depressed-patients-with-and-without-posttraumatic-stress-disorder
#1
Ewa A Ogłodek
BACKGROUND: Both proinflammatory cytokines and oxidative stress are considered an imbalance between the cellular production of reactive oxygen species and the antioxidant defense mechanisms. An inflammatory response that occurs in depression leads to a synergy between pro-inflammatory cytokines and oxidative stress. This synergy induces common signal transduction pathways that boost the inflammatory cascade. The object of this study was to assess the concentrations of inflammatory and oxidative status biomediators such as MIP-1α, PMN elastase, MDA, and IL-12 in depressed patients with and without posttraumatic stress disorder (PTSD), and with PTSD alone...
August 26, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29338912/-surgical-outcomes-of-traumatic-cervical-fractures-in-patients-with-ankylosing-spondylitis
#2
Alberto Isla Guerrero, Beatriz Mansilla Fernández, Borja Hernández Garcia, Álvaro Gómez de la Riva, María Luisa Gandía González, Elena Isla Paredes
OBJECTIVE: Ankylosing spondylitis is an inflammatory rheumatic disease mainly affecting the axial skeleton. The rigid spine may secondarily develop osteoporosis, further increasing the risk of spinal fracture. In this study, we reviewed fractures in patients with ankylosing spondylitis that had been clinically diagnosed to better define the mechanism of injury, associated neurological deficit, predisposing factors, and management strategies. METHODS: Between January 2004 and December 2014, 6 patients with ankylosing spondylitis and neurological complications after injuries were treated...
January 12, 2018: Neurocirugía
https://www.readbyqxmd.com/read/29338843/current-status-of-animal-models-of-posttraumatic-stress-disorder-behavioral-and-biological-phenotypes-and-future-challenges-in-improving-translation
#3
REVIEW
Jessica Deslauriers, Mate Toth, Andre Der-Avakian, Victoria B Risbrough
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has required active collaboration between clinical and preclinical scientists. Modeling PTSD is challenging, as it is a heterogeneous disorder with ≥20 symptoms. Clinical research increasingly utilizes objective biological measures (e.g., imaging, peripheral biomarkers) or nonverbal behaviors and/or physiological responses to complement verbally reported symptoms. This shift toward more-objectively measurable phenotypes enables refinement of current animal models of PTSD, and it supports the incorporation of homologous measures across species...
November 20, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29336486/preventing-posttraumatic-stress-disorder-following-childbirth-and-traumatic-birth-experiences-a-systematic-review
#4
Lisanne F de Graaff, Adriaan Honig, Mariëlle G van Pampus, Claire A I Stramrood
INTRODUCTION: Between 9 and 44% of women experience giving birth as traumatic, and 3% of women develop a posttraumatic stress disorder following childbirth. Knowledge on risk factors is abundant, but studies on treatment are limited. This study aimed to present an overview of means to prevent traumatic birth experiences and childbirth-related posttraumatic stress disorder. MATERIAL AND METHODS: Major databases (Cochrane; Embase; PsycINFO; PubMed (Medline)) were searched using combinations of the key words and their synonyms...
January 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29335663/improving-mental-health-treatment-utilization-in-military-veterans-examining-the-effects-of-perceived-need-for-care-and-social-support
#5
Robert Graziano, Eric B Elbogen
Objective: Many veterans with mental health problems do not adequately utilize needed care. Research has focused on identifying barriers to mental health care in veterans. Method: The current study adds to existing literature by examining whether perceived need for treatment and social support affect treatment utilization in a national longitudinal survey of Iraq and Afghanistan veterans (n = 1090). Results: The Health Beliefs Model (HBM) postulates that a key reason why patients fail to obtain needed care is their belief "it's up to me to handle my own problems...
September 2017: Military Psychology
https://www.readbyqxmd.com/read/29335360/activity-in-the-ventral-medial-prefrontal-cortex-is-necessary-for-the-therapeutic-effects-of-extinction-in-rats
#6
Elizabeth A Fucich, Denisse Paredes, Madeleine O Saunders, David A Morilak
Poor response and high relapse rates remain problematic in the treatment of stress-related psychiatric disorders like depression and posttraumatic stress disorder (PTSD). While mechanisms of pharmacotherapies are intensely studied, little is known about mechanisms of behavioral therapy that could inform improved treatments. We have previously demonstrated the therapeutic effects of extinction learning as a behavioral intervention modeling exposure therapy in rats. In the present study, we tested the hypothesis that activity in the ventral medial prefrontal cortex (vmPFC) during extinction is necessary for its therapeutic effects...
January 15, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29334643/longitudinal-determinants-of-depression-among-world-trade-center-health-registry-enrollees-14-15-years-after-the-9-11-attacks
#7
Melanie H Jacobson, Christina Norman, Angela Nguyen, Robert M Brackbill
BACKGROUND: Exposure to the September 11, 2001 (9/11) terrorist attacks has been found to be associated with posttraumatic stress disorder (PTSD) and comorbid PTSD and depression up to 10-11 years post-disaster. However, little is known about the longitudinal predictors of mental health conditions over time. METHODS: We examined longitudinal determinants of depression within strata of PTSD among 21,258 enrollees of the World Trade Center Health Registry who completed four questionnaires over 14 years of follow-up (Wave 1 in 2003-04; Wave 2 in 2005-06; Wave 3 in 2011-12; and Wave 4 in 2015-16)...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29334642/examining-the-latent-structure-mechanisms-for-comorbid-posttraumatic-stress-disorder-and-major-depressive-disorder
#8
Margo C Hurlocker, Desirae N Vidaurri, Lisa-Ann J Cuccurullo, Kelly Maieritsch, C Laurel Franklin
BACKGROUND: Posttraumatic stress disorder (PTSD) is a complex psychiatric illness that can be difficult to diagnose, due in part to its comorbidity with major depressive disorder (MDD). Given that researchers have found no difference in prevalence rates of PTSD and MDD after accounting for overlapping symptoms, the latent structures of PTSD and MDD may account for the high comorbidity. In particular, the PTSD Negative Alterations in Cognition and Mood (NACM) and Hyperarousal factors have been characterized as non-specific to PTSD...
January 8, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29334531/dangerously-numb-opioids-benzodiazepines-chronic-pain-and-posttraumatic-stress-disorder
#9
Mark Sullivan
No abstract text is available yet for this article.
December 6, 2017: Pain
https://www.readbyqxmd.com/read/29332549/the-role-of-sexual-abuse-in-trauma-symptoms-delinquent-and-suicidal-behaviors-and-criminal-justice-outcomes-among-females-in-a-juvenile-justice-diversion-program
#10
Krystel Tossone, Madison Wheeler, Fredrick Butcher, Jeff Kretschmar
Female juvenile justice-involved (JJI) youth experience more sexual abuse (SA) than their non-JJI counterparts or their male JJI counterparts. This study examines SA's role among JJI females ( N = 1,307) in a behavioral health diversion program. Results indicate that SA increases the risk of psychological trauma, particularly posttraumatic stress and depression. SA also increases the odds of suicidal behavior, running away, and substance use. SA females have the same odds of successfully completing behavioral health diversion and being charged with any offense or misdemeanor after termination as non-SA females...
October 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29332541/after-the-escape-physical-abuse-of-offspring-posttraumatic-stress-disorder-and-the-legacy-of-political-violence-in-the-dprk
#11
Clifton R Emery, Jieun Yoo, Amia Lieblich, Randall Hansen
What is the relationship between victimization by political violence against women in North Korea and later physical abuse of offspring? This article examines the relationships between victimization by political violence, posttraumatic stress disorder (PTSD), alcohol abuse/dependence, and abuse of offspring after arrival in South Korea. A random sample of 204 female North Korean defectors was used to test hypotheses. An oral history conducted with a survivor of North Korean political violence is provided in an appendix to contextualize the results...
October 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29332534/mediated-effects-of-coping-on-mental-health-outcomes-of-african-american-women-exposed-to-physical-and-psychological-abuse
#12
Chmaika P Mills, Hope M Hill, Joshua A D Johnson
Few studies have assessed the individual symptoms of posttraumatic stress disorder (PTSD) as separate mental health consequences of intimate partner abuse (IPA). This study examined the role of coping strategies associated with symptoms of PTSD in a community sample of African American women who have experienced abuse ( N = 128). The results revealed that nonphysical abuse was more prevalent than physical abuse. Specific symptoms of PTSD expressed depended on the type of abuse experienced and the type of coping strategies utilized...
February 2018: Violence Against Women
https://www.readbyqxmd.com/read/29332494/an-evaluation-of-adolescent-and-young-adult-re-victimization-experiences-problematic-substance-use-and-negative-consequences
#13
D J Angelone, Tiffany Marcantonio, Jessica Melillo
We investigated substance use and negative consequences in women who experienced an initial sexual assault (SA) in high school and subsequently in college. More than 650 participants completed questionnaires assessing substance use/consequences, SA history, and posttraumatic stress disorder (PTSD) symptomology. Revictimized women reported differential substance use/consequences relative to controls underscoring the need to conceptualize adolescence as a key developmental period with a unique pathway to a subsequent SA, especially in association with substance use...
June 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29331353/mechanisms-of-sex-differences-in-fear-and-posttraumatic-stress-disorder
#14
REVIEW
Teniel Sonya Ramikie, Kerry James Ressler
Following sexual maturity, females disproportionately have higher rates of posttraumatic stress disorder (PTSD) and experience greater symptom severity and chronicity as compared with males. This observation has led many to examine sex differences in PTSD risk factors. Though relatively few, these studies reveal that the root causes of PTSD sex differences are complex, and partly represent interactions between sex-specific nonbiological and biological risk factors, which differentially shape PTSD vulnerability...
November 21, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29329597/does-cognitive-behavioral-therapy-alter-mental-defeat-and-cognitive-flexibility-in-patients-with-panic-disorder
#15
Shinobu Nagata, Yoichi Seki, Takayuki Shibuya, Mizue Yokoo, Tomokazu Murata, Yoichi Hiramatsu, Fuminori Yamada, Hanae Ibuki, Noriko Minamitani, Naoki Yoshinaga, Muga Kusunoki, Yasushi Inada, Nobuko Kawasoe, Soichiro Adachi, Keiko Oshiro, Daisuke Matsuzawa, Yoshiyuki Hirano, Kensuke Yoshimura, Michiko Nakazato, Masaomi Iyo, Akiko Nakagawa, Eiji Shimizu
OBJECTIVE: Mental defeat and cognitive flexibility have been studied as explanatory factors for depression and posttraumatic stress disorder. This study examined mental defeat and cognitive flexibility scores in patients with panic disorder (PD) before and after cognitive behavioral therapy (CBT), and compared them to those of a gender- and age-matched healthy control group. RESULTS: Patients with PD (n = 15) received 16 weekly individual CBT sessions, and the control group (n = 35) received no treatment...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329352/interpersonal-trauma-moderates-the-relationship-between-personality-factors-and-suicidality-of-individuals-with-posttraumatic-stress-disorder
#16
Yongjoon Yoo, Hyeon-Ju Park, Soowon Park, Maeng Je Cho, Seong-Jin Cho, Ji Yeon Lee, Soo-Hee Choi, Jun-Young Lee
Individuals with posttraumatic stress disorder (PTSD) are more prone to suicidal ideation and behavior. While those who have experienced interpersonal trauma exhibit more suicidality than those who have experienced non-interpersonal trauma, it is unclear how the traumatic effects are related to an individual's personality characteristics. This study examined the association between interpersonal trauma and personality factors with suicidality, and elucidated the moderating role of interpersonal trauma in individuals with PTSD...
2018: PloS One
https://www.readbyqxmd.com/read/29329048/characterizing-anger-related-affect-in-individuals-with-posttraumatic-stress-disorder-using-ecological-momentary-assessment
#17
Elizabeth E Van Voorhees, Paul A Dennis, Eric B Elbogen, Bernard Fuemmeler, Lydia C Neal, Patrick S Calhoun, Jean C Beckham
This study employed secondary analyses of existing ecological momentary assessment (EMA) data to characterize hostile and irritable affect in the day-to-day experience of 52 smokers with, and 65 smokers without, posttraumatic stress disorder (PTSD). EMA monitoring occurred over a mean of 8.2 days, and participants responded to an average of 2.8 random prompts/day. Analyses included Wilcoxon rank sum tests of group differences, and path analyses of cross-lagged multilevel models. Participants with PTSD endorsed a significantly higher proportion of total EMA entries indicating hostile affect and irritable affect than did individuals without PTSD...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29328956/predicting-post-breakup-distress-and-growth-in-emerging-adulthood-the-roles-of-relationship-satisfaction-and-emotion-regulation
#18
Jerika C Norona, Miri Scharf, Deborah P Welsh, Shmuel Shulman
With a sample of emerging adults (N = 110; 72% female) this brief report utilized self-report measures to examine the role of relationship satisfaction and emotion regulation strategies assessed at age 20 in predicting breakup distress and posttraumatic growth three years later. Results showed that higher relationship satisfaction is associated with less future breakup distress. Emotion regulation explained the ways individuals cope with distress; cognitive appraisal (in contrast to emotional suppression) predicted higher growth after experiencing a breakup...
January 9, 2018: Journal of Adolescence
https://www.readbyqxmd.com/read/29328948/psychopathology-and-episodic-future-thinking-a-systematic-review-and-meta-analysis-of-specificity-and-episodic-detail
#19
D J Hallford, D W Austin, K Takano, F Raes
Episodic future thinking (EFT) refers to the mental simulation of future events that might be personally-experienced; a crucial mental process in adaptation. Psychiatric disorders are associated with deficits in recalling episodic memory, however, no study has reviewed the empirical literature to assess for similar deficits in EFT. A systematic review comparing psychiatric groups with control groups on the specificity and episodic detail of EFT returned 19 eligible studies. An overall effect of g = -0.84 (95%CI = -1...
January 5, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29328008/-posttraumatic-stress-disorder-current-insights-in-diagnostics-treatment-and-prevention
#20
A Lok, J L Frijling, M van Zuiden
- Posttraumatic stress disorder (PTSD) is a psychiatric disorder that may develop after traumatic events.- PTSD is one of the most prevalent psychiatric disorders in the Netherlands, with an estimated lifetime prevalence of 7%.- Recurrent re-experiencing of the traumatic event is the most characteristic PTSD symptom.- Recognition of PTSD may be hampered by the heterogeneous symptomatology, avoidance to talk about the trauma and highly frequent comorbid psychiatric and somatic comorbidity.- Feelings of guilt and shame may also influence reported trauma history...
2018: Nederlands Tijdschrift Voor Geneeskunde
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