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https://www.readbyqxmd.com/read/29245046/physiological-and-self-report-responses-of-parents-of-children-with-autism-spectrum-disorder-to-children-crying
#1
Yagmur Ozturk, Andrea Bizzego, Gianluca Esposito, Cesare Furlanello, Paola Venuti
Little is known about the physiological response of parents of children with Autism Spectrum Disorder (ASD) to crying of children who have already received the diagnosis of ASD. This study aimed to compare cardiac dynamics via Inter-Beat Interval (IBI) and self-reported emotional states of parents of children with ASD and of parents with typically developing (TD) children while listening to crying of children with ASD (ASD cry) and of typically developing children (TD cry). Analyses revealed higher IBI in parents of children with ASD than IBI in parents of TD children while listening to both cry groups; however no differences on self-reported emotional states were observed...
December 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29245045/relations-between-problem-behaviors-perceived-symptom-severity-and-parenting-in-adolescents-and-emerging-adults-with-asd-the-mediating-role-of-parental-psychological-need-frustration
#2
Lisa M Dieleman, Sarah S W De Pauw, Bart Soenens, Elien Mabbe, Rachel Campbell, Peter Prinzie
Research in parents of youngsters with Autism Spectrum Disorder (ASD) increasingly documents associations between children's problem behaviors and symptom severity and more dysfunctional and less adaptive parenting behaviors. However, the mechanisms underlying these associations have not been examined thoroughly. This study examines the mediating role of parental need frustration in the relation between child maladjustment (i.e., problem behavior and autism severity) and parenting behavior (i.e., controlling and autonomy-supportive parenting)...
December 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29244797/association-between-maternal-hypothyroidism-and-autism-spectrum-disorders-in-the-children
#3
Darios Getahun, Steven J Jacobsen, Michael J Fassett, Deborah A Wing, Anny H Xiang, Vicki Chiu, Morgan R Peltier
OBJECTIVE: To determine if hypothyroidism is associated with ASD and how this association is influenced by race-ethnicity, sex, and timing of exposure. METHODS: A retrospective cohort study was conducted using records from 397201 children who were delivered from 1991-2011 and remained health plan members from 1993-2014. RESULTS: Children of hypothyroid women had higher ASD rates than children of women without the diagnosis (2.14 vs. 1.62/1000 person-years; and adjusted hazard ratios [adj...
December 15, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29243998/adjacent-segment-disease-after-thoracic-pedicle-screw-fixation
#4
Nitin Agarwal, Robert F Heary, Prateek Agarwal
OBJECTIVE Pedicle screw fixation is a technique widely used to treat conditions ranging from spine deformity to fracture stabilization. Pedicle screws have been used traditionally in the lumbar spine; however, they are now being used with increasing frequency in the thoracic spine as a more favorable alternative to hooks, wires, or cables. Although safety concerns, such as the incidence of adjacent-segment disease (ASD) after cervical and lumbar fusions, have been reported, such issues in the thoracic spine have yet to be addressed thoroughly...
December 15, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29243511/acute-stress-disorder-and-c-reactive-protein-in-patients-with-acute-myocardial-infarction
#5
Hannes Bielas, Rebecca E Meister-Langraf, Jean-Paul Schmid, Jürgen Barth, Hansjörg Znoj, Ulrich Schnyder, Mary Princip, Roland von Känel
Background Myocardial infarction-triggered acute stress disorder (ASD) and subclinical inflammation associate with the development of posttraumatic stress disorder, and worsen the prognosis of myocardial infarction patients. We examined the relationship between ASD severity and C-reactive protein levels in patients with acute myocardial infarction. Methods We assessed 190 patients (median age 59 years; 83% men) with a verified myocardial infarction within 48 h of an acute coronary intervention. Circulating levels of C-reactive protein were categorized according to their prognostic risk for cardiovascular disease: 0 to <5, 5 to <10, 10 to <20, and ≥ 20 mg/l...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29243100/parents-use-of-complementary-health-approaches-for-young-children-with-autism-spectrum-disorder
#6
Olivia J Lindly, Sheryl Thorburn, Karen Heisler, Nuri M Reyes, Katharine E Zuckerman
Knowledge of why parents use complementary health approaches (CHA) for children with autism spectrum disorder (ASD) is limited. We conducted a mixed methods study to better understand factors influencing parents' decision to use CHA for ASD. Parent-reported data about CHA use were collected on a probability sample of 352 young children with ASD in Denver, Colorado; Los Angeles, California; or Portland, Oregon. Follow-back interviews were conducted with 31 parents. CHA use was negatively associated with older child age and positively associated with parents' belief ASD has major consequences, living in Portland or Denver, and medication use...
December 14, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29243097/validating-the-revised-illness-perception-questionnaire-as-a-measure-of-parent-perceptions-of-autism-spectrum-disorder
#7
Sarah S Mire, Tammy D Tolar, Christie M Brewton, Natalie S Raff, Shannon L McKee
The illness perception questionnaire (IPQ) and its revision (IPQ-R) measure perceptions about health-related diagnoses and the influence of cognitions on coping. In this study, the factor structure of a version revised for use with autism spectrum disorder (ASD) was investigated with a sample of parents (n = 361) whose children have ASD. Subsequently, multidimensional item response theory was used to evaluate item and subscale properties. Results indicated items from five of the seven IPQ-R-ASD scales loaded as expected, though subscales related to control were not distinct...
December 14, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29242499/high-internal-noise-and-poor-external-noise-filtering-characterize-perception-in-autism-spectrum-disorder
#8
Woon Ju Park, Kimberly B Schauder, Ruyuan Zhang, Loisa Bennetto, Duje Tadin
An emerging hypothesis postulates that internal noise is a key factor influencing perceptual abilities in autism spectrum disorder (ASD). Given fundamental and inescapable effects of noise on nearly all aspects of neural processing, this could be a critical abnormality with broad implications for perception, behavior, and cognition. However, this proposal has been challenged by both theoretical and empirical studies. A crucial question is whether and how internal noise limits perception in ASD, independently from other sources of perceptual inefficiency, such as the ability to filter out external noise...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29242177/implementing-a-mental-health-care-program-and-home-based-training-for-mothers-of-children-with-autism-spectrum-disorder-in-an-urban-population-in-bangladesh-protocol-for-a-feasibility-assessment-study
#9
Aliya Naheed, Kamrun Nahar Koly, Helal Uddin Ahmed, Shaheen Akhter, M M Jalal Uddin, Mary C Smith Fawzi, Subhash Chandir, Muzharul Mannan, Saima Hossain, Charles Nelson, Kerim Munir
BACKGROUND: Mothers of children with autism spectrum disorder (ASD) have reported a higher level of depression than mothers of children with other neurodevelopmental disorders in both developed and developing countries. Mothers are the lifetime caregivers of children with ASD, and a high burden of depression can negatively impact their ability to provide care. However, access to mental health services in primary care is limited, given the scarcity of qualified providers in Bangladesh...
December 14, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29241371/capitalizing-on-technology-for-developing-communication-skills-in-autism-spectrum-disorder-a-single-case-study
#10
Veena Mohan, Suja Kurian Kunnath, Vineetha Sara Philip, Lakshmi Santha Mohan, Neethu Thampi
PURPOSE: In this case study, we discuss the application of a patient-centred clinical approach that led to the use of an assisted communication platform to combat severe communicative deficit in a child with autism spectrum disorder (ASD). METHODS: Initial assessment at four years of age revealed that the patient had rudimentary communication skills, with significant sensory integration dysfunction manifested as oral, olfactory, and tactile seeking behaviours; self-stimulatory behaviour; and complete dependence on caregiver for activities of daily living...
December 15, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29241119/bench-to-bedside-review-possible-role-of-vitamin-d-in-autism-spectrum-disorder
#11
REVIEW
Feiyong Jia, Ling Shan, Bing Wang, Honghua Li, Chunyue Miao, Zhida Xu, Ching-Po Lin, Khaled Saad
Autism spectrum disorder (ASD) is a group of dysfunctions in social interaction, communication, and behaviors. Studies have demonstrated that vitamin D deficiency during pregnancy and in individuals increased the risk of ASD. A genetic polymorphism study has pinpointed that genotype AA/A-allele of GC rs4588 in children is associated with ASD, which encodes the vitamin D binding protein. Translating the mentioned points into clinical practice, several clinical trials have demonstrated that vitamin D supplementation can improve the core symptoms in children with ASD...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29240517/sensory-processing-patterns-in-autism-attention-deficit-hyperactivity-disorder-and-typical-development
#12
Lauren M Little, Evan Dean, Scott Tomchek, Winnie Dunn
AIMS: The purpose of this study was to examine sensory processing in children ages 3-14 years with autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and typical development (TD) using the Sensory Profile 2nd Edition (Dunn, 2014). METHODS: Participants included 239 children (ASD = 77; ADHD = 78; TD = 84) matched on age and gender. Multivariate analysis of covariance was used to compare the extent to which the three grsoups differed on sensory processing patterns (i...
December 14, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/29240304/weight-status-diet-quality-perceived-stress-and-functional-health-of-caregivers-of-children-with-autism-spectrum-disorder
#13
Xiaoyin Sara Li, Jennifer A Pinto-Martin, Aleda Thompson, Jesse Chittams, Tanja V E Kral
PURPOSE: Caring for children with autism spectrum disorder (ASD) can be highly demanding and can put significant strain on caregivers. To date, little is known about the extent to which caregivers of children with ASD experience increased levels of stress which may adversely affect health outcomes. The purpose of this secondary analysis was to compare caregivers of children with ASD and caregivers of typically developing children (TDC) in weight status, diet quality, perceived stress related to the parenting role, and functional health and well-being...
December 14, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29239865/large-databases-for-pediatric-research-on-children-with-autism-spectrum-disorder
#14
Karen A Kuhlthau, L Charles Bailey, Briella L Baer, Daniel L Coury, J Kiely Law, Donna S Murray, Hanieh Razzaghi, Christopher B Forrest, Paul H Lipkin
OBJECTIVE: This article reviews the data available in 3 large databases for use in conducting studies of children with autism spectrum disorder (ASD). METHODS: The article describes the data structure, data elements, and strengths and weaknesses of the 3 data sets. RESULTS: Each of the 3 data sets, the Interactive Autism Network (IAN), the Autism Treatment Network (ATN), and PEDSnet have large cohorts of children with ASD. IAN has strengths in patient-reported measures, ATN in clinical characterization, and PEDSnet in health care encounters and electronic medical record data...
December 11, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29239739/endophenotypes-a-conceptual-link-between-anorexia-nervosa-and-autism-spectrum-disorder
#15
Z C Zhou, D B McAdam, D R Donnelly
The paper, by translating the concept and the two models of endophenotype (EP), strengthens the hypothesis that there exists a linkage between anorexia nervosa (AN) and autism spectrum disorder (ASD). Specifically, the paper synthesizes empirical research that supported the idea that individuals with AN and individuals with ASD share similarities with respect to their neurocognitive EPs and temperament EPs. The paper then introduces an innovative structure to emphasize the subtle difference between neurocognitive EPs and temperament EPs in relation to AN and ASD...
November 24, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29239145/line-1-retrotransposons-in-healthy-and-diseased-human-brain
#16
REVIEW
Nicole A Suarez, Angela Macia, Alysson R Muotri
Long interspersed element-1 (LINE-1 or L1) is a transposable element with the ability to self-mobilize throughout the human genome. The L1 elements found in the human brain is hypothesized to date back 56 million years ago and has survived evolution, currently accounting for 17% of the human genome. L1 retrotransposition has been theorized to contribute to somatic mosaicism. This review focuses on the presence of L1 in the healthy and diseased human brain, such as in autism spectrum disorders (ASD). Throughout this exploration, we will discuss the impact L1 has on neurological disorders that can occur throughout the human lifetime...
December 14, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/29238949/a-pilot-of-a-brief-positive-parenting-program-on-children-newly-diagnosed-with-autism-spectrum-disorder
#17
Debra H Zand, Margaret W Bultas, Stephen Edward McMillin, Donna Halloran, Taryn White, Donnamarie McNamara, Katherine J Pierce
Disruptive behaviors can be of comparable or greater concern to parents than the core symptoms of Autism Spectrum Disorder (ASD). Provision of effective interventions to address these behaviors within the first year of initial diagnosis holds great potential for improving the child's, parents', and family's functioning. We piloted a four-session, manualized, positive parenting program on 21 parents of newly diagnosed children ages 2 through 12 years using a mixed methods design. Seventy-five percent of parents completed four sessions, with 100% reporting high levels of service satisfaction...
December 14, 2017: Family Process
https://www.readbyqxmd.com/read/29238634/asa-classification-as-a-risk-stratification-tool-in-adult-spinal-deformity-surgery-a-study-of-5805-patients
#18
Sulaiman Somani, John Di Capua, Jun S Kim, Kevin Phan, Nathan J Lee, Parth Kothari, Joung-Heon Kim, James Dowdell, Samuel K Cho
Study Design: Retrospective analysis of prospectively collected data. Objectives: Adult spinal deformity (ASD) surgery is a highly complex procedure that has high complication rates. Risk stratification tools can improve patient management and may lower complication rates and associated costs. The goal of this study was to identify the independent association between American Society of Anesthesiologists (ASA) class and postoperative outcomes following ASD surgery...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29238311/assessing-risk-of-bias-in-randomized-controlled-trials-for-autism-spectrum-disorder
#19
Paola Matiko Martins Okuda, Cheryl Klaiman, Jessica Bradshaw, Morganne Reid, Hugo Cogo-Moreira
Aim: To determine construct validity and reliability indicators of the Cochrane risk of bias (RoB) tool in the context of randomized clinical trials (RCTs) for autism spectrum disorder (ASD). Methods: Confirmatory factor analysis was used to evaluate a unidimensional model consisting of 9 RoB categorical indicators evaluated across 94 RCTs addressing interventions for ASD. Results: Only five of the nine original RoB items returned good fit indices and so were retained in the analysis...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29236921/intermittent-theta-burst-transcranial-magnetic-stimulation-for-autism-spectrum-disorder-an-open-label-pilot-study
#20
Caio Abujadi, Paul E Croarkin, Bianca B Bellini, Helena Brentani, Marco A Marcolin
OBJECTIVE: Theta-burst stimulation (TBS) modulates synaptic plasticity more efficiently than standard repetitive transcranial magnetic stimulation delivery and may be a promising modality for neuropsychiatric disorders such as autism spectrum disorder (ASD). At present there are few effective interventions for prefrontal cortex dysfunction in ASD. We report on an open-label, pilot study of intermittent TBS (iTBS) to target executive function deficits and restricted, repetitive behaviors in male children and adolescents with ASD...
December 11, 2017: Revista Brasileira de Psiquiatria
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