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Pediatric-size heart valve

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https://www.readbyqxmd.com/read/29572879/patient-specific-atrial-hemodynamics-of-a-double-lumen-neonatal-cannula-in-correct-caval-position
#1
Jamil Muhammad, Mohammad Rezaeimoghaddam, Bilgesu Cakmak, Reza Rasooli, Ece Salihoglu, Yahya Yıldız, Kerem Pekkan
Clinical success of pediatric veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is associated with the double lumen cannula cardiovascular device design as well as its anatomic orientation in the atrium. The positions of cannula ports with respect to the vena cavae and the tricuspid valve are believed to play a significant role on device hemodynamics. Despite various improvements in ECMO catheters, especially for the neonatal and congenital heart patients, it is still challenging to select a catalogue size that would fit to most patients optimally...
March 23, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29546472/transcatheter-pulmonary-valve-replacement-current-state-of-art
#2
REVIEW
Wail Alkashkari, Amani Alsubei, Ziyad M Hijazi
PURPOSE OF REVIEW: The past couple of decades have brought tremendous advances to the field of pediatric and adult congenital heart disease (CHD). Percutaneous valve interventions are now a cornerstone of not just the congenital cardiologist treating patients with congenital heart disease, but also-and numerically more importantly-for adult interventional cardiologists treating patients with acquired heart valve disease. Transcatheter pulmonary valve replacement (tPVR) is one of the most exciting recent developments in the treatment of CHD and has evolved to become an attractive alternative to surgery in patients with right ventricular outflow tract (RVOT) dysfunction...
March 15, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29543640/anesthesia-for-percutaneous-pulmonary-valve-implantation-a-case-series
#3
Rafael Arboleda Salazar, Jane Heggie, Piotr Wolski, Eric Horlick, Mark Osten, Massimiliano Meineri
BACKGROUND: Twenty percent of patients born with congenital heart disease present with right ventricular outflow tract abnormalities. These patients require multiple surgical procedures in their lifetime. Transcatheter pulmonary valve replacement (TPVR) has become a viable alternative to conventional pulmonary valve and right ventricular outflow tract surgery in pediatric and adult populations. In this retrospective review, we analyze the perioperative management of adult patients who underwent TPVR in our center...
March 14, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29177686/preclinical-animal-study-of-the-nipro-ventricular-assist-device-for-use-in-pediatric-patients
#4
Noritsugu Naito, Yoshiaki Takewa, Satoru Kishimoto, Kei Iizuka, Toshihide Mizuno, Tomonori Tsukiya, Minoru Ono, Eisuke Tatsumi
Although the outcomes of patients with end-stage heart failure treated with implantable left ventricular assist devices have improved, extracorporeal left ventricular assist devices continue to play an important role, especially in pediatric patients. The present study aimed to examine the long-term biocompatibility of a small-sized extracorporeal pneumatic left ventricular assist device (NIPRO-LVAD) used in a 30- to 90-day animal experiment. The NIPRO-LVAD was designed for pediatric patients or small-sized adults...
November 24, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/28501374/the-effect-of-the-superior-cavopulmonary-anastomosis-on-ventricular-remodeling-in-infants-with-single-ventricle
#5
MULTICENTER STUDY
Renee Margossian, Victor Zak, Amanda J Shillingford, Anthony M Hlavacek, James F Cnota, Michael D Puchalski, Jami C Levine, Brian W McCrindle, Meryl S Cohen, Karen Altmann, Piers C Barker, Daphne T Hsu, Steven D Colan
BACKGROUND: Infants with single ventricular physiology have volume and pressure overload that adversely affect ventricular mechanics. The impact of superior cavopulmonary anastomosis (SCPA) on single left ventricles versus single right ventricles is not known. METHODS: As part of the Pediatric Heart Network placebo-controlled trial of enalapril in infants with single ventricular physiology, echocardiograms were obtained before SCPA and at 14 months and analyzed in a core laboratory...
July 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28391001/three-dimensional-mitral-valve-morphology-and-age-related-trends-in-children-and-young-adults-with-structurally-normal-hearts-using-transthoracic-echocardiography
#6
Matthew A Jolley, Sunil J Ghelani, Adi Adar, David M Harrild
BACKGROUND: The mitral valve has a complex three-dimensional (3D) morphology that is incompletely described by two-dimensional echocardiography (echo). Three-dimensional echo provides a more robust tool to analyze the mitral valve. The shape of the mitral annulus and leaflets, and differences with age, have not been described by 3D echo in normal children. Our objective was to characterize and quantify the 3D mitral valve morphology in children with normal transthoracic echocardiograms over a broad spectrum of age and to identify differences in valve shape with age...
June 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/27995570/hydrodynamic-assessment-of-aortic-valves-prepared-from-porcine-small-intestinal-submucosa
#7
Sharan Ramaswamy, Makensley Lordeus, Omkar V Mankame, Lilliam Valdes-Cruz, Steven Bibevski, Sarah M Bell, Ivan Baez, Frank Scholl
Infants and children born with severe cardiac valve lesions have no effective long term treatment options since currently available tissue or mechanical prosthetic valves have sizing limitations and no avenue to accommodate the growth of the pediatric patient. Tissue engineered heart valves (TEHVs) which could provide for growth, self-repair, infection resistance, and long-term replacement could be an ideal solution. Porcine small intestinal submucosa (PSIS) has recently emerged as a potentially attractive bioscaffold for TEHVs...
March 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/27925367/transient-severe-tricuspid-regurgitation-after-transplantation-of-an-extremely-oversized-donor-heart-in-a-child-does-size-matter-a-case-report
#8
J Birnbaum, S M Ulrich, R Schramm, C Hagl, A Lehner, M Fischer, N A Haas, B Heineking
In pediatric heart transplantation, the size of the donor organ is an important criterion for organ allocation. Oversized donor hearts are often accepted with good results, but some complications in relation to a high donor-recipient ratio have been described. Our patient was transplanted for progressive heart failure in dilated cardiomyopathy. The donor-to-recipient weight ratio was 3 (donor weight 65 kg, recipient weight 22 kg). The intra-operative echocardiography before chest closure showed excellent cardiac function, no tricuspid valve regurgitation, and a normal central venous pressure...
February 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/27680418/contrast-enhanced-high-pitch-computed-tomography-in-pediatric-patients-without-electrocardiography-triggering-and-sedation-comparison-of-cardiac-image-quality-with-conventional-multidetector-computed-tomography
#9
RANDOMIZED CONTROLLED TRIAL
Michael Esser, Sergios Gatidis, Matthias Teufel, Inés Ketelsen, Konstantin Nikolaou, Jürgen F Schäfer, Ilias Tsiflikas
OBJECTIVE: The aim of this study was to compare image quality of anatomical cardiac details without electrocardiography triggering, sedation, or heart rate-regulating drugs in contrast-enhanced pediatric chest computed tomography (CT), using high-pitch CT (HPCT) versus conventional pitch-mode technique (multidetector CT [MDCT]). METHODS: After written informed consent, 55 patients (median age, 11 years; range, 3-17 years) were prospectively included in this institutional review board-approved study...
January 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27665220/surgical-reconstruction-of-semilunar-valves-in-the-growing-child-should-we-mimic-the-venous-valve-a-simulation-study
#10
Peter E Hammer, Erin G Roberts, Sitaram M Emani, Pedro J Del Nido
OBJECTIVES: Neither heart valve repair methods nor current prostheses can accommodate patient growth. Normal aortic and pulmonary valves have 3 leaflets, and the goal of valve repair and replacement is typically to restore normal 3-leaflet morphology. However, mammalian venous valves have bileaflet morphology and open and close effectively over a wide range of vessel sizes. We propose that they might serve as a model for pediatric heart valve reconstruction and replacement valve design...
February 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26004027/use-of-a-1-0-tesla-open-scanner-for-evaluation-of-pediatric-and-congenital-heart-disease-a-retrospective-cohort-study
#11
MULTICENTER STUDY
Jimmy C Lu, James C Nielsen, Layne Morowitz, Muzammil Musani, Maryam Ghadimi Mahani, Prachi P Agarwal, El-Sayed H Ibrahim, Adam L Dorfman
BACKGROUND: Open cardiovascular magnetic resonance (CMR) scanners offer the potential for imaging patients with claustrophobia or large body size, but at a lower 1.0 Tesla magnetic field. This study aimed to evaluate the efficacy of open CMR for evaluation of pediatric and congenital heart disease. METHODS: This retrospective, cross-sectional study included all patients ≤18 years old or with congenital heart disease who underwent CMR on an open 1.0 Tesla scanner at two centers from 2012-2014...
2015: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/25652317/percutaneous-pulmonary-valve-implantation-5-years-of-follow-up-does-age-influence-outcomes
#12
MULTICENTER STUDY
Sharon Borik, Andrew Crean, Eric Horlick, Mark Osten, Kyong-Jin Lee, Rajiv Chaturvedi, Mark K Friedberg, Brian W McCrindle, Cedric Manlhiot, Lee Benson
BACKGROUND: Percutaneous pulmonary valve implantation (PPVI) is a safe, less invasive alternative to surgical valve replacement for the congenital heart disease patient with right ventricular (RV) outflow tract dysfunction. The aim of this study was to determine whether reverse RV remodeling after PPVI was persistent in the longer term and whether timing of PPVI influenced outcomes. METHODS AND RESULTS: Consecutive patients from the pediatric and adult congenital heart disease programs were enrolled...
February 2015: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/25573076/utility-of-a-dedicated-pediatric-cardiac-anticoagulation-program-the-boston-children-s-hospital-experience
#13
Jenna M Murray, Amy Hellinger, Roger Dionne, Loren Brown, Rosemary Galvin, Suzanne Griggs, Karen Mittler, Kathy Harney, Shannon Manzi, Christina VanderPluym, Annette Baker, Patricia O'Brien, Cheryl O'Connell, Christopher S Almond
Congenital heart disease is the leading cause of stroke in children. Warfarin therapy can be difficult to manage safely in this population because of its narrow therapeutic index, multiple drug and dietary interactions, small patient size, high-risk cardiac indications, and lack of data to support anticoagulation recommendations. We sought to describe our institution's effort to develop a dedicated cardiac anticoagulation service to address the special needs of this population and to review the literature. In 2009, in response to Joint Commission National Patient Safety Goals for Anticoagulation, Boston Children's Hospital created a dedicated pediatric Cardiac Anticoagulation Monitoring Program (CAMP)...
April 2015: Pediatric Cardiology
https://www.readbyqxmd.com/read/25440099/impact-of-initial-shunt-type-on-cardiac-size-and-function-in-children-with-single-right-ventricle-anomalies-before-the-fontan-procedure-the-single-ventricle-reconstruction-extension-trial
#14
RANDOMIZED CONTROLLED TRIAL
Peter C Frommelt, Eric Gerstenberger, James F Cnota, Meryl S Cohen, Jessica Gorentz, Kevin D Hill, J Blaine John, Jami C Levine, Jimmy Lu, William T Mahle, Rachel T McCandless, Luc Mertens, Gail D Pearson, Carolyn Spencer, Deepika Thacker, Ismee A Williams, Pierre C Wong, Jane W Newburger
BACKGROUND: In children with single right ventricular (RV) anomalies, changes in RV size and function may be influenced by shunt type chosen at the time of the Norwood procedure. OBJECTIVES: The study sought to identify shunt-related differences in echocardiographic findings at 14 months and ≤6 months pre-Fontan in survivors of the Norwood procedure. METHODS: We compared 2-dimensional and Doppler echocardiographic indices of RV size and function, neo-aortic and tricuspid valve annulus dimensions and function, and aortic size and patency at 14...
November 11, 2014: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/25011622/computational-simulations-of-flow-dynamics-and-blood-damage-through-a-bileaflet-mechanical-heart-valve-scaled-to-pediatric-size-and-flow
#15
B Min Yun, Doff B McElhinney, Shiva Arjunon, Lucia Mirabella, Cyrus K Aidun, Ajit P Yoganathan
Despite pressing needs, there are currently no FDA approved prosthetic valves available for use in the pediatric population. This study is performed for predictive assessment of blood damage in bileaflet mechanical heart valves (BMHVs) with pediatric sizing and flow conditions. A model of an adult-sized 23 mm St. Jude Medical (SJM) Regent(™) valve is selected for use in simulations, which is scaled in size for a 5-year old child and 6-month old infant. A previously validated lattice-Boltzmann method (LBM) is used to simulate pulsatile flow with thousands of suspended platelets for cases of adult, child, and infant BMHV flows...
September 22, 2014: Journal of Biomechanics
https://www.readbyqxmd.com/read/23870153/food-and-drug-administration-commentary-on-a-new-paradigm-for-obtaining-marketing-approval-for-pediatric-sized-prosthetic-heart-valves
#16
EDITORIAL
Fernando Aguel, Steven B Kurtzman, Sonna Patel-Raman, Matthew Hillebrenner, Bram D Zuckerman
No abstract text is available yet for this article.
October 2013: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/23796593/a-new-paradigm-for-obtaining-marketing-approval-for-pediatric-sized-prosthetic-heart-valves
#17
Ajit P Yoganathan, Mark Fogel, Susan Gamble, Michael Morton, Paul Schmidt, Jeff Secunda, Sara Vidmar, Pedro Del Nido
OBJECTIVE: Congenital heart valve disease is one of the most common abnormalities in children. There are limited technological solutions available for treating children with congenital heart valve diseases. The aim of this study is to provide the details of the consensus reached in terms of pediatric definitions, design approach, in vitro testing, and clinical trials, which may be used as guidance for developing prosthetic heart valves for the pediatric indication. METHODS: In stark contrast to the various designs of adult-sized replacement valves available in the market, there are no Food and Drug Administration (FDA)-approved prosthetic heart valves available for use in the pediatric population...
October 2013: Journal of Thoracic and Cardiovascular Surgery
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