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https://www.readbyqxmd.com/read/29747858/timing-of-referral-of-patients-with-severe-isolated-tricuspid-valve-regurgitation-to-surgeons-from-a-french-nationwide-database
#1
Julien Dreyfus, Nicolas Ghalem, Eric Garbarz, Claire Cimadevilla, Patrick Nataf, Alec Vahanian, Gilbert Caranhac, David Messika-Zeitoun
Series evaluating the results of isolated tricuspid valve surgery (ITVS) are rare and often limited by small sample size, selection bias, and/or long period of enrollment. Based on a mandatory administrative national database, we collected all consecutive ITVS performed in France during a 2-year period (2013 and 2014), the type of intervention, clinical profile, and in-hospital mortality and complications. During the 2-year period, 241 patients underwent an ITVS in France (84 repairs and 157 replacements). In-hospital mortality was high (10%), and most patients experienced at least 1 complication (65%) with a 19% rate of major complications (death, need for dialysis, or need for mechanical support using extracorporeal membrane oxygenation)...
April 12, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29747569/systolic-characteristics-and-dynamic-changes-of-the-mitral-valve-in-different-grades-of-ischemic-mitral-regurgitation-insights-from-3d-transesophageal-echocardiography
#2
Caroline Morbach, Diego Bellavia, Stefan Störk, Lissa Sugeng
BACKGROUND: Mitral regurgitation in ischemic heart disease (IMR) is a strong predictor of outcome but until now, pathophysiology is not sufficiently understood and treatment is not satisfying. We aimed to systematically evaluate structural and functional mitral valve leaflet and annular characteristics in patients with IMR to determine the differences in geometric and dynamic changes of the MV between significant and mild IMR. METHODS: Thirty-seven patients with IMR (18 mild (m)MR, 19 significant (moderate+severe) (s)MR) and 33 controls underwent TEE...
May 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29743998/transcatheter-aortic-valve-in-valve-procedure-in-patients-with-bioprosthetic-structural-valve-deterioration
#3
REVIEW
Ross M Reul, Mahesh K Ramchandani, Michael J Reardon
Surgical aortic valve replacement is the gold standard procedure to treat patients with severe, symptomatic aortic valve stenosis or insufficiency. Bioprosthetic valves are used for surgical aortic valve replacement with a much greater prevalence than mechanical valves. However, bioprosthetic valves may fail over time because of structural valve deterioration; this often requires intervention due to severe bioprosthetic valve stenosis or regurgitation or a combination of both. In select patients, transcatheter aortic valve replacement is an alternative to surgical aortic valve replacement...
July 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29743996/emerging-transcatheter-options-for-tricuspid-regurgitation
#4
REVIEW
Ankur Kalra, Angad S Uberoi, Azeem Latib, Sahil Khera, Stephen H Little, Deepak L Bhatt, Michael J Reardon, Neal S Kleiman, Colin M Barker
Tricuspid regurgitation (TR) presents as either primary valve pathology or secondary to pulmonary or left-sided heart disease. Severe TR portends a worse prognosis independent of age, right ventricular size and function, severe left ventricular dysfunction, and increased pulmonary arterial pressures. Surgical treatment for TR has mostly been limited to patients undergoing mitral valve repair since those at high surgical risk are not candidates for traditional TR surgery. For these patients, minimally invasive techniques could be of great benefit, yet these techniques have been slow to develop because of the various anatomic and physiological aspects of the tricuspid valve apparatus...
July 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29741486/computed-tomography-based-oversizing-and-incidence-of-para-valvular-aortic-regurgitation-and-permanent-pacemaker-implantation-with-a-new-generation-self-expanding-transcatheter-heart-valve
#5
Ung Kim, Philipp Blanke, Stephan Windecker, Albert M Kasel, Ulrich Schäfer, Darren Walters, Axel Linke, Herve Le Breton, Gerhard Schymik, Mark S Spence, Lars Sondergaard, Mohammed Abdel-Wahab, Stephen Worthley, Didier Tchetche, Hermann Reichenspurner, Mickael Ohana, Stephanie L Sellers, Jonathon A Leipsic
AIMS: We aimed to evaluate the relationship between CT-based annular perimeter oversizing and the incidence of paravalvular aortic regurgitation (PAR) and permanent pacemaker (PPM) implantation in patients treated with the new self-expanding CENTERA transcatheter heart valve (THV) for severe aortic stenosis. METHODS AND RESULTS: 198 patients in the CENTERA-EU trial were stratified priori into four groups based on the perimeter oversizing (2.5%-10%, 10-15%, 15-20% and >20%)...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29740114/significantly-increased-low-shear-rate-viscosity-blood-elastic-modulus-and-rbc-aggregation-in-adults-following-cardiac-surgery
#6
Yi-Fan Wu, Po-Shun Hsu, Chien-Sung Tsai, Pin-Cheng Pan, Yeng-Long Chen
Open heart surgeries are common for treating ischemic and heart valve disease. During cardiac surgery, cardiopulmonary bypass (CPB) can temporarily take over the function of heart and lungs. However, elevated red blood cell (RBC) aggregation may lead to the common side-effects such as microinfarction. We investigated blood physical properties changes and the correlation between blood microstructure, viscoelastic response and biochemical changes following surgery with CPB. We examined shear-rate dependent blood viscosity, elasticity and RBC aggregate size in the pre-surgery disease state, post-surgery state and long-term recovery state of cardiac surgical patients...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29739020/how-do-transcatheter-heart-valves-fit-in-mitral-annuloplasty-rings-and-which-combination-can-be-recommended
#7
Roya Ostovar, Ralf-Uwe Kuehnel, Michael Erb, Martin Hartrumpf, Thomas Claus, Robert Haase, Johannes M Albes
BACKGROUND:  Transcatheter heart valve (THV) as valve-in-ring is increasingly used in the mitral position. Semi-rigid rings may serve as a more appropriate scaffold for proper anchoring of a THV as they may change from their oval to a round shape thereby fitting to the implanted THV. METHODS:  One rigid and five semi-rigid rings of four manufacturers, Edwards Physio I and II, Sorin 3D Memo, Medtronic Simulus, and St. Jude Medical (SJM) Saddle and SJM Sequin, with sizes 28 to 36 mm and Edwards Sapien III THV 23, 26, and 29 mm were used...
May 8, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29736853/is-mri-equivalent-to-ct-in-the-guidance-of-tavr-a-pilot-study
#8
Agnes Mayr, Gert Klug, Sebastian J Reinstadler, Hans-Josef Feistritzer, Martin Reindl, Christian Kremser, Christof Kranewitter, Nikolaos Bonaros, Guy Friedrich, Gudrun Feuchtner, Bernhard Metzler
OBJECTIVES: To compare a comprehensive cardiovascular magnetic resonance imaging (MRI) protocol with contrast-enhanced computed tomography angiography (CTA) for guidance in transcatheter aortic valve replacement (TAVR) evaluation. METHODS AND RESULTS: Non-contrast three-dimensional (3D) 'whole heart' MRI imaging for aortic annulus sizing and measurements of coronary ostia heights, contrast-enhanced MRI angiography (MRA) for evaluation of transfemoral routes as well as aortoiliofemoral-CTA were performed in 16 patients referred for evaluation of TAVR...
May 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29733826/pulmonary-valve-replacement-a-single-institution-comparison-of-surgical-and-transcatheter-valves
#9
Vikas Sharma, Eric R Griffiths, Aaron W Eckhauser, Robert G Gray, Mary H Martin, Chong Zhang, Angela P Presson, Phillip T Burch
BACKGROUND: Transcatheter pulmonary valve replacement (TPVR) is increasingly utilized to address residual or recurrent right ventricular outflow tract pathology in congenital heart disease patients. We aimed to evaluate clinical outcomes and resource utilization comparing TPVR to surgical pulmonary valve replacement (SPVR) for this patient population. METHODS: From January 2010 until December 2015, 224 patients underwent pulmonary valve replacement (SPVR n=100 and TPVR n=124)...
May 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29730689/right-heart-dilatation-in-a-fetus-with-an-abnormal-foramen-ovale-valve-an-indicator-of-interatrial-communication-restriction
#10
Wenjia Lei, Miao Fan, Meilian Wang, Yu Wang, Wei Sun, Xue Sun, Ying Zhang
AIMS: Foramen ovale (FO) valve with a shape or motion abnormality is frequently detected during routine obstetric ultrasonic examinations. However, the hemodynamics mechanism of this entity remains unclear. The purpose of the study is to determine the relevance of interatrial communication restriction and resultant morphological modifications. MATERIALS AND METHODS: We reviewed the echocardiographic records of fetuses with isolated abnormal FO valve evaluated between January of 2010 and december of 2016...
May 2, 2018: Medical Ultrasonography
https://www.readbyqxmd.com/read/29675905/transient-left-anterior-and-septal-fascicular-blocks-after-self-expandable-percutaneous-transcatheter-aortic-valve-implantation
#11
Andrés R Pérez-Riera, Raimundo Barbosa-Barros, Mariana F Cabral de Oliveira, Rodrigo Daminello-Raimundo, Luiz C de Abreu, Kjell Nikus
Transcatheter aortic valve implantation (TAVI) is indicated in severe symptomatic aortic stenosis, when there is intermediate-high surgical risk, or a condition considered inoperable, as in the case of "porcelain aorta" that could turn clamping or cannulation of the ascending aorta hazardous in open-heart surgery. Among the complications of this less invasive procedure, intraventricular conduction disorders subsequent to the procedure stand out. TAVI causes worsening of intraventricular dromotropic disorders in more than 75% of the cases, with the presence of preexisting right bundle branch block and first-degree atrioventricular block, deep prosthesis implant, male gender, size of the aortic annulus smaller than the prosthesis, and porcelain aorta being predictive of requirement for permanent pacemaker implant...
April 19, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29622984/tricuspid-valve-repair-with-dacron-band-versus-devega-or-segmental-annuloplasty-hospital-outcome-and-short-term-results
#12
Ahmed Abdelgawad, Mona Ramadan, Heba Arafat, Ahmed Abdel Aziz
Background: The purpose of this study was to compare the hospital outcome and short term results of tricuspid valve (TV) repair with three repair techniques for functional tricuspid regurgitation (TR), namely, flexible Dacron band, DeVega and segmental annuloplasty. Methods: A total of 60 patients underwent TV repair at National Heart Institute from January 2013 to November 2014, of which 20 had DeVega procedure (DV), 20 had a segmental annuloplasty (SA) procedure and 20 had a Dacron band (DB) procedure...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29617495/early-clinical-results-of-perceval-sutureless-aortic-valve-in-139-patients-freeman-experience
#13
Syed Saleem Mujtaba, Simon Ledingham, Asif Raza Shah, Stephen Clark, Thasee Pillay, Stephan Schueler
OBJECTIVE: The aim of this retrospective study is to evaluate the safety and performance of the Perceval sutureless valve in patients undergoing aortic valve replacement. We report the 30-day clinical outcomes of 139 patients. METHODS: From January 2014 to December 2016, 139 patients underwent sutureless aortic valve replacement. Their operation notes, National Adult Cardiac Surgery Database and perioperative transoesophageal echocardiography findings were studied retrospectively...
January 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29588729/optimising-the-haemodynamics-of-aortic-valve-in-valve-procedures
#14
Ren Jie Yao, Matheus Simonato, Danny Dvir
Bioprosthetic surgical valves are increasingly implanted during cardiac surgery, instead of mechanical valves. These tissue valves are associated with limited durability and as a result transcatheter valve-in-valve procedures are performed to treat failed bioprostheses. A relatively common adverse event of aortic valve-in-valve procedures is residual stenosis. Larger surgical valve size, supra-annular transcatheter heart valve type, as well as higher transcatheter heart valve implantation depth, have all been shown to reduce the incidence of elevated post-procedural gradients...
May 2017: Interventional Cardiology
https://www.readbyqxmd.com/read/29579634/separation-and-characterization-of-allergenic-polymerized-impurities-from-cephalosporin-for-injection-by-trap-free-two-dimensional-high-performance-size-exclusion-chromatography-%C3%A3-reversed-phase-liquid-chromatography-coupled-with-ion-trap-time-of-flight-mass
#15
Yu Xu, Dandan Wang, Bingqi Zhu, Lan Tang, Jian Wang
As requested by regulatory authorities, polymerized impurities are an important issue of quality control. In this study, we presented the utilization of a trap-free two-dimensional chromatography, which was consisted by a high performance size exclusion chromatography (HPSEC) and a reversed-phase liquid chromatography (RP-LC) coupled to ion trap time-of-flight mass spectrometry with positive mode of electrospray ionization, to separate and characterize ten allergenic impurities in ceftazidime for injection, cefazolin sodium for injection, cefoperazone sodium and sulbactam sodium for injection and cefamandole nafate for injection...
March 20, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29575373/the-anatomical-components-of-the-cardiac-outflow-tract-of-chondrichthyans-and-actinopterygians
#16
Miguel Lorenzale, Miguel A López-Unzu, Cristina Rodríguez, Borja Fernández, Ana C Durán, Valentín Sans-Coma
The outflow tract of the fish heart is the segment interposed between the ventricle and the ventral aorta. It holds the valves that prevent blood backflow from the gill vasculature to the ventricle. The anatomical composition, histological structure and evolutionary changes in the fish cardiac outflow tract have been under discussion for nearly two centuries and are still subject to debate. This paper offers a brief historical review of the main conceptions about the cardiac outflow tract components of chondrichthyans (cartilaginous fish) and actinopterygians (ray-finned fish) which have been put forward since the beginning of the nineteenth century up to the current day...
March 25, 2018: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/29572879/patient-specific-atrial-hemodynamics-of-a-double-lumen-neonatal-cannula-in-correct-caval-position
#17
Jamil Muhammad, Mohammad Rezaeimoghaddam, Bilgesu Cakmak, Reza Rasooli, Ece Salihoglu, Yahya Yıldız, Kerem Pekkan
Clinical success of pediatric veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is associated with the double lumen cannula cardiovascular device design as well as its anatomic orientation in the atrium. The positions of cannula ports with respect to the vena cavae and the tricuspid valve are believed to play a significant role on device hemodynamics. Despite various improvements in ECMO catheters, especially for the neonatal and congenital heart patients, it is still challenging to select a catalogue size that would fit to most patients optimally...
March 23, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29568912/clinical-study-of-prenatal-ultrasonography-combined-with-t%C3%A2-box-transcription-factor-1-as-a-biomarker-for-the-diagnosis-of-congenital-heart-disease
#18
Bingcheng Guo, Jing Xiao, Long Li, Shuanglong Wang, Lijuan Wang, Shuyong Liu
Congenital heart disease (CHD) seriously threatens fetal health. Therefore, prenatal examination to detect deformity is extremely important. The present study aimed to investigate the clinical application value of prenatal ultrasonography combined with molecular biology methods in the diagnosis of fetal CHD. A total of 1,000 pregnant women who had received fetal ultrasonography to examine fetal CHD were enrolled. Ultrasounds were performed for fetal heart examination and diagnosis, mainly on fetal heart position, size, structure and function, and heart valve morphology and function...
March 14, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29566799/branch-pulmonary-artery-valve-implantation-reduces-pulmonary-regurgitation-and-improves-right-ventricular-size-function-in-patients-with-large-right-ventricular-outflow-tracts
#19
Athar M Qureshi, Neha Bansal, Doff B McElhinney, Younes Boudjemline, Tom J Forbes, Nicola Maschietto, Shabana Shahanavaz, John P Cheatham, Richard Krasuski, Luke Lamers, Massimo Chessa, Brian H Morray, Bryan H Goldstein, Cory V Noel, Yunfei Wang, Matthew J Gillespie
OBJECTIVES: The authors sought to assess the intermediate-term effects of percutaneous placed valves in the branch pulmonary artery (PA) position. BACKGROUND: Most patients with large right ventricular outflow tracts (RVOTs) are excluded from available percutaneous pulmonary valve options. In some of these patients, percutaneous branch PA valve implantation may be feasible. The longer-term effects of valves in the branch PA position is unknown. METHODS: Retrospective data were collected on patients with significant pulmonary regurgitation who had a percutaneous branch PA valve attempted...
March 26, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29553978/peripheral-pruning-a-safe-approach-to-thinning-extra-large-anterolateral-thigh-flaps
#20
Stephen L Viviano, Farrah C Liu, Paul J Therattil, Edward S Lee, Jonathan D Keith
BACKGROUND: Thinning of anterolateral thigh (ALT) flaps has been described to achieve optimal contouring. Previous studies caution against thinning large flaps owing to the risk of vascular compromise leading to partial or total flap necrosis. This study aims to demonstrate a reliably safe method for thinning extra-large (>240 cm) flaps. METHODS: A retrospective review of 53 consecutive ALT flaps performed at a single institution was completed. Of these flaps, 18 (34%) were thinned primarily by sharp excision of sub-Scarpa's fat along the periphery of the flap using loupe magnification...
April 2018: Annals of Plastic Surgery
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