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Two-piece heart valve

Michael Englert, Leslie Brown, Walter Vetter
Countercurrent chromatography (CCC) is a separation technique based on the liquid-liquid partitioning of compounds between the two phases of a biphasic solvent system. Limitations in the separation efficiency and peak capacity of one-dimensional (1D) CCC often result in insufficiently resolved peaks. Therefore, partially resolved peak fractions have to be rechromatographed in order to improve the yield and purity. Additional solvent evaporation steps can be circumvented by the application of two-dimensional CCC (2D CCC)...
October 20, 2015: Analytical Chemistry
Seshasailam Venkateswaran, Mei Wu, Peter J Gwynne, Ailsa Hardman, Annamaria Lilienkampf, Salvatore Pernagallo, Garry Blakely, David G Swann, Maurice P Gallagher, Mark Bradley
Nosocomial infections due to bacteria have serious implications on the health and recovery of patients in a variety of medical scenarios. Since bacterial contamination on medical devices contributes to the majority of nosocomical infections, there is a need for redesigning the surfaces of medical devices, such as catheters and tracheal tubes, to resist the binding of bacteria. In this work, polyurethanes and polyacrylates/acrylamides, which resist binding by the major bacterial pathogens underpinning implant-associated infections, were identified using high-throughput polymer microarrays...
September 17, 2014: Journal of Materials Chemistry. B, Materials for Biology and Medicine
Kyoko Hayashida, Keiichi Kanda, Tomonori Oie, Yoshihiro Okamoto, Hatsue Ishibashi-Ueda, Masaaki Onoyama, Tsutomu Tajikawa, Kenkichi Ohba, Hitoshi Yaku, Yasuhide Nakayama
As a practical concept of regenerative medicine, we have focused on in vivo tissue engineering utilizing the foreign body reaction. Plastic substrates for valvular leaflet organization, consisting of two pieces assembled with a small aperture were inserted into a microporous polyurethane conduit scaffold. The assembly was placed in the subcutaneous spaces of Japanese white rabbits for 1 month. After the substrates were pulled out from the harvested implant, valve leaflet-shaped membranous tissue was formed inside the tubular scaffold as designed...
July 2008: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
D R Boughner, M Haldenby, A J Hui, J Dunmore-Buyze, E A Talman, W K Wan
BACKGROUND AND AIM OF THE STUDY: Glutaraldehyde-fixed bovine pericardial tissue used in the construction of valvular bioprostheses undergoes repeated bending stress during the cardiac cycle. To bend smoothly, internal tissue shearing is required. The effect of glutaraldehyde fixation on internal shear properties of this material was examined. METHODS: Pericardium from each of 12 bovine hearts was cut into two pieces; one piece was retained as fresh tissue, the other was glutaraldehyde-fixed...
November 2000: Journal of Heart Valve Disease
C Stacchino, G Bona, S Rinaldi, F Vallana
The Pericarbon Stentless valve (PS) in an unstented bioprosthesis made of glutaraldehyde tanned bovine pericardium. Its design concept and chemical fixation process are based on those developed for the stented Pericarbon valve, which has been in clinical use for eight years. The two-sheet design and the special suture pattern with which the two pieces of pericardium are attached aim at avoiding stress concentration during function. The resulting cylindrical structure is a relatively low-profile valve conduit, which can be further trimmed by the implanting surgeon to the individual patient's specific anatomical requirements...
July 1995: Journal of Heart Valve Disease
(no author information available yet)
No abstract text is available yet for this article.
January 1995: Health Devices
M Kanazawa, H Tsuboi, H Gohra, T Katoh, Y Fujimura, K Esato
A 36-year-old woman with corrected transposition (C-TGA) of great arteries with associated systemic atrioventricular valve (A-V valve) regurgitation was presented. Cineangiography revealed that the right sided ventricle was morphologic left ventricle, and left sided ventricle was morphologic right ventricle. In addition, severe systemic A-V valvular regurgitation (Sellers IV) was demonstrated. Under the diagnosis of C-TGA with associated A-V valvular regurgitation, left sided atrioventricular valve replacement was performed using 29 mm SJM valve...
April 1992: [Zasshi] [Journal]
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