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Mitraclip, percutaneous mitral valve

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https://www.readbyqxmd.com/read/29208340/different-indicators-for-postprocedural-mitral-stenosis-caused-by-single-or-multiple-clip-implantation-after-percutaneous-mitral-valve-repair
#1
Yuji Itabashi, Hiroto Utsunomiya, Shunsuke Kubo, Yukiko Mizutani, Hirotsugu Mihara, Mitsushige Murata, Robert J Siegel, Saibal Kar, Keiichi Fukuda, Takahiro Shiota
BACKGROUND: Postprocedural mitral stenosis (MS) is a main limitation for MitraClip™ (Abbot Vascular, Inc., Santa Clara, CA, USA) procedure. The purpose of this study was to detect the preprocedural predictors of high transmitral pressure gradient (TMPG) after MitraClip™ implantation, which indicated postprocedural mitral stenosis (MS). METHODS: We studied 79 patients who were implanted with MitraClip™ in our institute. Before the procedure, mitral valve orifice area (MVOA), and anterior-posterior (AP) and medial-lateral (ML) mitral annular diameters were measured at diastole using three-dimensional (3D) transesophageal echocardiography (TEE) data set...
December 2, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29204737/initial-slovenian-experience-with-mitraclip-therapy-careful-selection-of-patients-is-crucial-for-optimal-outcome
#2
Jana Ambrožič, Marta Cvijič, Mojca Bervar, Špela Mušič, Matjaž Bunc
BACKGROUND: MitraClip is a percutaneous mitral repair technology increasingly used for high surgical risk patients with primary or secondary mitral regurgitation. We describe initial Slovenian experience with MitraClip and discuss the importance of identifying the suitable candidates for this procedure. METHODS: We retrospectively analyzed the first 10 patients (mean age 75.6 ± 6.9 years, logistic Euroscore 28.4 ± 10.9%) with severe and moderate to severe mitral regurgitation (8 secondary, 1 primary and 1 mixed etiology) who underwent a MitraClip procedure between January 2015 and February 2017...
December 4, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29161956/percutaneous-repair-of-mitral-valve-regurgitation-in-patients-with-severe-heart-failure-comparison-with-optimal-medical-treatment
#3
Nicolas Geis, Philip Raake, Markus Lewening, Derliz Mereles, Emmanuel Chorianopoulos, Lutz Frankenstein, Hugo A Katus, Raffi Bekeredjian, Sven T Pleger
BACKGROUND: Occurrence of severe mitral valve (MV) regurgitation (MR) is an independent negative predictor of mortality in patients with severe systolic heart failure (HF). This study examines clinical effects and cardiac reverse remodelling in patients with severe systolic HF receiving percutaneous mitral valve repair (PMVR) using MitraClip in comparison to patients receiving optimal medical therapy only. METHODS: Between 2010 and 2014, 86 patients (Society of Thoracic Surgeons score: 10...
November 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29152276/percutaneous-mitral-valve-repair-with-the-mitraclip-nt%C3%A2-system-in-a-patient-presenting-with-prolonged-cardiogenic-shock
#4
Dominik Buckert, Sinisa Markovic, Markus Kunze, Jochen Wöhrle, Wolfgang Rottbauer, Daniel Walcher
The MitraClip NT™ system for the treatment of severe mitral valve regurgitation is effective and safe - even for patients suffering from cardiogenic shock. The use of an intra-aortic balloon pump expands the range of possible applications to this particular group of challenging patients.
November 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29148247/does-the-severity-of-left-ventricular-systolic-dysfunction-impact-outcomes-of-mitraclip-therapy-how-low-is-too-low
#5
EDITORIAL
Mehmet Cilingiroglu, Abdul Hakeem
Percutaneous mitral valve repair for symptomatic severe mitral regurgitation has rapidly evolved as a viable therapeutic option for high-surgical risk patients. Both randomized clinical studies as well as real world registry data have demonstrated significant improvement in severity of MR and clinical outcomes. In carefully selected patients with severely reduced left ventricular systolic function and severe symptomatic MR, Mitraclip therapy seems to show promise.
November 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29148095/vascular-complications-after-percutaneous-mitral-valve-repair-and-venous-access-closure-using-suture-or-closure-device
#6
Birgit Steppich, Felix Stegmüller, Philipp Moritz Rumpf, Jürgen Pache, Carolin Sonne, Hasema Lesevic, Daniel Braun, Jörg Hausleiter, Albert Markus Kasel, Ilka Ott
OBJECTIVE: The aim of this study was to assess the impact of different access-site closure strategies, suture or closure device (Proglide, Abbott Vascular), on vascular and bleeding complications after percutaneous mitral valve repair (MitraClip, Abbott Vascular). BACKGROUND: Considering the high-risk profile in patients receiving percutaneous mitral valve repair, complications related to the large 24 Fr access sheath and its relation to the closure technique have not been evaluated so far...
November 16, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29122275/bleeding-complications-after-percutaneous-mitral-valve-repair-with-the-mitraclip
#7
Maria Isabel Körber, Julia Silwedel, Kai Friedrichs, Victor Mauri, Michael Huntgeburth, Roman Pfister, Stephan Baldus, Volker Rudolph
Bleeding after cardiac surgery or cardiovascular interventions is associated with worse patient outcome. Only very limited data are available on the subject of bleeding after percutaneous edge-to-edge mitral valve repair (PMVR). We performed a single center analysis including 347 consecutive patients who underwent PMVR. Bleeding was defined according to the Mitral Valve Academic Research Consortium (MVARC) end point definition. The incidence of MVARC bleeding was 21.6% (n = 75), whereas major MVARC bleeding (hemoglobin decrease ≥3 g/dl) occurred in 7...
October 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29113720/spanish-cardiac-catheterization-and-coronary-intervention-registry-26th-official-report-of-the-spanish-society-of-cardiology-working-group-on-cardiac-catheterization-and-interventional-cardiology-1990-2016
#8
Ana María Serrador Frutos, Pilar Jiménez-Quevedo, Armando Pérez de Prado, Manuel Pan Álvarez-Ossorio
INTRODUCTION AND OBJECTIVES: The Working Group on Cardiac Catheterization and Interventional Cardiology presents its annual report on the activity data for 2016. METHODS: All Spanish hospitals with catheterization laboratories were invited to voluntarily contribute their activity data. The information was collected online and was analyzed mainly by an independent company. RESULTS: In 2016, 106 centers participated in the national registry; 80 of these centers are public...
November 4, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29033048/comparison-of-outcome-after-percutaneous-mitral-valve-repair-with-the-mitraclip-in-patients-with-versus-without-atrial-fibrillation
#9
Juliëtte F Velu, Friso A Kortlandt, Tom Hendriks, Remco A J Schurer, Ad J van Boven, Karel T Koch, M Marije Vis, Jose P Henriques, Jan J Piek, Ben J L Van den Branden, Jeroen Schaap, Benno J Rensing, Martin J Swaans, Berto J Bouma, Jan A S Van der Heyden, Jan Baan
Percutaneous mitral valve repair with the MitraClip is an established treatment for patients with mitral regurgitation (MR) who are inoperable or at high risk for surgery. Atrial Fibrillation (AF) frequently coincides with MR, but only scarce data of the influence of AF on outcome after MitraClip is available. The aim of the current study was to compare the clinical outcome after MitraClip treatment in patients with versus without atrial fibrillation. Between January 2009 and January 2016, all consecutive patients treated with a MitraClip in 5 Dutch centers were included...
December 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29032936/editorial-commentary-percutaneous-edge-to-edge-mitral-valve-repair-with-mitraclip-state-of-the-art-and-new-perspectives
#10
EDITORIAL
Flavia Ballocca
No abstract text is available yet for this article.
September 28, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29027267/percutaneous-repair-of-severe-mitral-valve-regurgitation-secondary-to-chordae-rupture-in-octogenarians-using-mitraclip
#11
Nicolas Geis, Philip Raake, Derliz Mereles, Emmanuel Chorianopoulos, Gabor Szabo, Hugo A Katus, Raffi Bekeredjian, Sven T Pleger
OBJECTIVES: The aim of this study was to assess feasibility and clinical effectiveness of the MitraClip device in octogenarians suffering from severe mitral valve regurgitation due to chordae rupture. BACKGROUND: The MitraClip procedure is a suitable technique in high-risk surgical patients to achieve safe and effective percutaneous repair of mitral valve regurgitation. Octogenarians show cumulative risk and social aspects hindering mitral valve surgery. No data exists regarding the use of the MitraClip device in high-risk octogenarians suffering from mitral valve chordae rupture...
October 12, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29025679/relation-of-residual-mitral-regurgitation-despite-elevated-mitral-gradients-to-risk-of-heart-failure-hospitalization-after-mitraclip-repair
#12
Richard Cheng, Sam Dawkins, Emily Tat, Moody Makar, Asma Hussaini, Raj R Makkar, Alfredo Trento, Robert J Siegel, Saibal Kar
Achieving minimal residual mitral regurgitation (MR) after percutaneous MitraClip repair is limited by iatrogenic mitral stenosis. It is unknown whether allowing moderately elevated postprocedural mean mitral gradients (MMGs) to achieve < moderate residual MR is preferable to moderate residual regurgitation. Patients with less-than-moderate residual MR but a MMG of ≥5 mm Hg (Group 1) were compared with patients with moderate residual MR (Group 2). The primary end point was heart failure hospitalization...
November 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28977372/improved-mitral-valve-coaptation-and-reduced-mitral-valve-annular-size-after-percutaneous-mitral-valve-repair-pmvr-using-the-mitraclip-system
#13
Johannes Patzelt, Yingying Zhang, Harry Magunia, Miriam Ulrich, Rezo Jorbenadze, Michal Droppa, Wenzhong Zhang, Henning Lausberg, Tobias Walker, Peter Rosenberger, Peter Seizer, Meinrad Gawaz, Harald F Langer
Aims: Improved mitral valve leaflet coaptation with consecutive reduction of mitral regurgitation (MR) is a central goal of percutaneous mitral valve repair (PMVR) with the MitraClip® system. As influences of PMVR on mitral valve geometry have been suggested before, we examined the effect of the procedure on mitral annular size in relation to procedural outcome. Methods and results: Geometry of the mitral valve annulus was evaluated in 183 patients undergoing PMVR using echocardiography before and after the procedure and at follow-up...
August 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28895061/valvular-heart-disease-in-women-differential-remodeling-and-response-to-new-therapies
#14
REVIEW
Jaya Chandrasekhar, George Dangas, Roxana Mehran
In the United States, valvular heart disease (VHD) has a prevalence of 2.5%, most commonly presenting as aortic stenosis (AS) or mitral valve regurgitation (MR) and increasingly observed to be of a degenerative etiology. Women frequently have latent symptoms despite significant disease, and it is therefore pertinent to consider both clinical symptoms and imaging findings for decision-making on treatment. Indeed, significant advances have been made in noninvasive imaging allowing for more accurate diagnosis and disease prognostication...
September 11, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28863973/current-status-of-mitraclip-for-patients-with-mitral-and-tricuspid-regurgitation
#15
REVIEW
Sidakpal S Panaich, Mackram F Eleid
Mitral valve regurgitation (MR) affects approximately 4 million people in the United States alone, increasing in prevalence with age. Approved by the Food and Drug Administration (FDA) in October 2013, percutaneous edge-to-edge transcatheter mitral valve repair (also known as the MitraClip system) has been used in over 40,000 patients globally. Additionally, there is keen interest and early exploration into the use of MitraClip for treatment of severe symptomatic tricuspid regurgitation, another undertreated disease with significant morbidity and mortality...
August 18, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28852577/sequential-venous-percutaneous-transluminal-angioplasty-and-balloon-dilatation-of-the-interatrial-septum-during-percutaneous-edge-to-edge-mitral-valve-repair
#16
Rezo Jorbenadze, Johannes Patzelt, Meinrad Gawaz, Peter Seizer, Harald F Langer
Percutaneous edge-to-edge mitral valve repair (PMVR) is widely used for selected, high-risk patients with severe mitral valve regurgitation (MR). This report describes a case of 81-year-old woman presenting with severe and highly symptomatic mitral valve regurgitation (MR) caused by a flail of the posterior mitral valve leaflet (PML). PMVR turned out to be challenging in this patient because of a stenosis and tortuosity of both iliac veins as well as sclerosis of the interatrial septum, precluding the vascular and left atrial access by standard methods, respectively...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28834079/safety-and-efficacy-of-mitraclip%C3%A2-therapy-in-patients-with-severely-impaired-left-ventricular-ejection-fraction-results-from-the-german-transcatheter-mitral-valve-interventions-trami-registry
#17
Nicolas A Geis, Miriam Puls, Edith Lubos, Christine S Zuern, Jennifer Franke, Robert Schueler, Ralph S von Bardeleben, Peter Boekstegers, Taoufik Ouarrak, Ralf Zahn, Hüseyin Ince, Jochen Senges, Hugo A Katus, Raffi Bekeredjian
AIMS: The aim of the present study was to assess the safety and efficacy of percutaneous mitral valve repair using the MitraClip™ device in patients with severely reduced systolic left ventricular (LV) function. METHODS AND RESULTS: Among 777 MitraClip™ implantations included in the German mitral valve registry, we identified 256 patients suffering from severely reduced LV function [ejection fraction (EF) <30%] in whom successful percutaneous mitral valve repair was performed...
August 18, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28820547/incidence-and-clinical-impact-of-cerebral-lesions-after-the-mitraclip%C3%A3-%C3%A2-procedure
#18
Sebastian Barth, Karsten Hamm, Stefan Fodor, Wilko Reents, Sebastian Kerber, Philipp Halbfass, Martina B Hautmann, Bernhard Schieffer, Hassan Soda
BACKGROUND: Clinically silent brain injury detected with cerebral magnetic resonance imaging (MRI) is well known after various cardiovascular interventions. Thus far, only one study has examined the periprocedural risk of cerebral ischemic events in patients undergoing percutaneous mitral valve reconstruction. The study aim was to examine the incidence and clinical impact of cerebral embolic events in patients undergoing percutaneous mitral valve reconstruction using the MitraClip® system...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28820546/initial-results-of-combined-mitraclip%C3%A3-%C3%A2-implantation-and-left-atrial-appendage-occlusion
#19
Xavier Freixa, Rodrigo Estévez-Loureiro, Fernando Carrasco-Chinchilla, Dabit Arzamendi, Pilar Jiménez-Quevedo, Luis Nombela-Franco, Ignacio Cruz-González, Ignacio J Amat-Santos, Manel Sabaté
BACKGROUND: Atrial fibrillation is present in 30-50% of patients undergoing percutaneous mitral valve repair. The presence of a formal contraindication to oral anticoagulation is also very common in these patients. In this context, percutaneous left atrial appendage occlusion (LAAO) may be a valid alternative for these patients. The study aim was to assess the feasibility, safety, and technical considerations of the combination of percutaneous mitral valve repair using the MitraClip system and LAAO...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28804054/elmstreet-esophageal-lesions-during-mitraclip%C3%A2-using-transesophagelechocardiography-trial
#20
Tobias Friedrich Ruf, Felix M Heidrich, Krunoslav M Sveric, Christian Pfluecke, Anna-Magdalena Stephan, Ruth H Strasser, Stephan Wiedemann
AIMS: We evaluated possible detrimental effects of transoesophageal echocardiography (TEE) on the oesophageal tissue during percutaneous mitral valve repair (PMVR). METHODS AND RESULTS: From March 2014 to July 2015, 186 patients were treated for severe mitral regurgitation (MR) with PMVR using the MitraClip® system. In 40 patients, esophagogastroduodenoscopy was performed due to symptoms related to the gastrointestinal tract. Based on the procedure's duration, patients were classified into group 1 (> 60 minutes, n=23) or into group 2 (< 60 minutes, n=17), respectively...
August 15, 2017: EuroIntervention
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