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Mitraclip, percutaneous mitral valve

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https://www.readbyqxmd.com/read/28069638/feasibility-and-predictors-of-early-discharge-after-percutaneous-edge-to-edge-mitral-valve-repair
#1
Corrado Tamburino, Sergio Buccheri, Antonio Popolo Rubbio, Salvatore Scandura, Maria Elena Di Salvo, Sarah Mangiafico, Sebastiano Immé, Giuseppe Caruso, Matteo Scalia, Antonio Condorelli, Marco Barbanti, Piera Capranzano, Davide Capodanno, Carmelo Grasso
BACKGROUND: Percutaneous edge-to-edge mitral valve repair (PMVR) recently emerged as an effective treatment modality for patients with severe mitral regurgitation (MR). Length of postprocedural hospital stay may represent a modifiable cost associated with percutaneous treatment. We looked at feasibility, predictors and safety of early discharge (ED), defined as hospital discharge within 72 hours, in patients undergoing PMVR. METHODS AND RESULTS: Consecutive patients treated with MitraClip from October 2008 to December 2015 were analysed...
January 9, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27989042/mitraclip%C3%A2-two-weeks-after-implantation
#2
Juliëtte F Velu, Hans H de Boer, Berto J Bouma, Jan Baan
A 73-year-old male received a percutaneous mitral valve repair with a MitraClip to treat severe (grade IV) symptomatic mitral regurgitation (MR). The MitraClip® procedure reduced the MR to grade I, but the patient died 14 days post-procedurally due to a pneumosepsis. Histological analysis of the MitraClip mesh covering showed a chronic inflammatory reaction with an abundance of multinucleated giant cells. Remarkably, signs of early onset clip-coverage were found, indicated by the presence of a few scattered myofibroblasts...
May 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27989041/left-atrial-and-left-ventricular-function-and-remodeling-following-percutaneous-mitral-valve-repair
#3
Christos Rammos, Tobias Zeus, Jan Balzer, Verena Veulemans, Katharina Hellhammer, Svenja Niebel, Malte Kelm, Tienush Rassaf
BACKGROUND: Mitral regurgitation causes left atrial (LA) and left ventricular (LV) dysfunction, dilatation, and remodeling. Following percutaneous mitral valve repair (PMVR) using the MitraClip® approach, reverse cardiac remodeling is desirable. To date, the influence of PMVR on LA and segmental LV function and remodeling has not been investigated in detail. METHODS: Twenty-six patients who received the MitraClip device were enrolled in an open-label, single-center observational study...
May 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27987271/previous-malignancy-is-an-independent-predictor-of-follow-up-mortality-after-percutaneous-treatment-of-mitral-valve-regurgitation-by-means-of-mitraclip
#4
Alper Öner, Hüseyin Ince, Liliya Paranskaya, Guido Schröder, Mohammad Sherif, Olga Thiele, Alla Neuhausen, Kische Stephan, Jasmin Ortak, Giuseppe D Ancona
AIMS: To investigate the prognostic burden of previously diagnosed and treated malignancies in candidates for percutaneous mitral valve repair (MVR) with MitraClip. METHODS AND RESULTS: A total of 165 patients underwent MVR and 19 (11.5%) had been previously treated for malignancy and considered healed with life expectancy over 1 year at time of percutaneous MVR. There was a significant trend for an increased overall risk profile (euroSCORE II 14.0±11.4 vs. 10...
December 16, 2016: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/27964904/immediate-and-12-month-outcomes-of-ischemic-versus-nonischemic-functional-mitral-regurgitation-in-patients-treated-with-mitraclip-from-the-2011-to-2012-pilot-sentinel-registry-of-percutaneous-edge-to-edge-mitral-valve-repair-of-the-european-society-of-cardiology
#5
Michele Pighi, Rodrigo Estevez-Loureiro, Francesco Maisano, Gian P Ussia, Gianni Dall'Ara, Olaf Franzen, Cécile Laroche, Magnus Settergren, Reidar Winter, Georg Nickenig, Martine Gilard, Carlo Di Mario
In literature, there are limited data comparing ischemic mitral regurgitation (I-MR) versus nonischemic MR regarding outcomes after percutaneous "edge-to-edge" repair. We aimed to describe the early and 12-month results after MitraClip device implantation regarding the 2 etiologies. From January 2011 to December 2012, the Transcatheter Valve Treatment Sentinel Pilot Registry included 452 patients with MR who underwent MitraClip procedure in 25 centers across Europe. The prevalent etiology was I-MR (235 patients, 52...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27933588/mitraclip-step-by-step-how-to-simplify-the-procedure
#6
REVIEW
M A Sherif, L Paranskaya, S Yuecel, S Kische, O Thiele, G D'Ancona, A Neuhausen-Abramkina, J Ortak, H Ince, A Öner
The MitraClip system is a device for percutaneous edge-to-edge reconstruction of the mitral valve in patients with severe mitral regurgitation who are deemed at high risk for surgery. Studies have underlined the therapeutic benefit of the MitraClip system for patients at extreme and high risk for mitral valve surgery, suffering from either degenerative or functional mitral regurgitation. The MitraClip procedure shows low peri-procedural complication rates, and a significant reduction in mitral regurgitation, as well as an improvement in functional capacity and most importantly quality of life...
December 8, 2016: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27875721/percutaneous-mitral-valve-repair-the-last-chance-for-symptoms-improvement-in-advanced-refractory-chronic-heart-failure
#7
Alessandra Berardini, Elena Biagini, Francesco Saia, Davide Stolfo, Mario Previtali, Francesco Grigioni, Bruno Pinamonti, Gabriele Crimi, Alessandro Salvi, Maurizio Ferrario, Antonio De Luca, Fabrizio Gazzoli, Maria Letizia Bacchi Reggiani, Claudia Raineri, Gianfranco Sinagra, Claudio Rapezzi
BACKGROUND: The role of percutaneous mitral valve repair (PMVR) in patients with end-stage heart failure (HF) and functional mitral regurgitation (FMR) is unclear. METHODS: Seventy-five consecutive patients with FMR grade≥3+ and severe HF symptoms despite optimal medical therapy and resynchronization therapy underwent PMVR with the MitraClip system (Abbott, Abbott Park, IL, USA) at 3 centers. Clinical evaluation, echocardiography and pro-BNP measurement were performed at baseline and at 6-month...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27860182/from-tricuspid-to-double-orifice-morphology-percutaneous-tricuspid-regurgitation-repair-with-the-mitraclip-device-in-congenitally-corrected-transposition-of-great-arteries
#8
Fabien Picard, Victor-Xavier Tadros, Anita W Asgar
Edge to edge transcatheter mitral valve repair with MitraClip (Abbott Vascular, Menlo Park, CA) is increasing for high-risk surgical patients with significant mitral regurgitation. Patients with congenitally corrected transposition of the great arteries (CCTGA) presenting with tricuspid valve regurgitation of a systemic right ventricle may represent particularly challenging candidates for MitraClip given their anatomy. We report the case of a 67-year-old gentleman with CCTGA and severe tricuspid regurgitation who was referred for MitraClip implantation after heart team consensus...
November 10, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27852483/mitraclip-therapy-for-mitral-regurgitation-primary-mitral-regurgitation
#9
REVIEW
G Athappan, Mohammad Qasim Raza, Samir R Kapadia
Primary mitral regurgitation (MR) owing to degenerative changes in the structural components of the mitral valve is a common acquired valvular pathology in the elderly. Surgical correction with mitral valve repair (MVRe) or replacement (MVR) is the mainstay of therapy. A significant proportion of patients are ineligible for MVRe/MVR owing to prohibitive surgical risk from advanced age, poor ventricular function, or associated comorbidities. Percutaneous mitral valve repair techniques have been developed to fill this void...
January 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/27852482/targeted-transseptal-access-for-mitraclip-percutaneous-mitral-valve-repair
#10
REVIEW
Gagan D Singh, Thomas W Smith, Jason H Rogers
Targeted transseptal puncture remains the most critical initial part of the overall MitraClip procedure. Care and attention must be implemented for patient safety in choosing the optimal puncture site. A consistent and step-by-step methodical approach is recommended. As experienced operators are targeting more complex and nontraditional pathologic conditions, use of adjunctive tools and maneuvers (outlined in this review) are paramount to achieving successful targeted transseptal access and ultimately procedural success...
January 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/27798059/quality-of-life-after-mitral-valve-intervention
#11
Matthew K H Tan, Omar A Jarral, Elizabeth H E Thong, Emaddin Kidher, Rakesh Uppal, Prakash P Punjabi, Thanos Athanasiou
Advancements in surgical technique and understanding of the pathophysiology of mitral valve (MV) dysfunction have led to improved outcomes. Seen as a development beyond measures of morbidity and mortality, health-related quality-of-life (HRQOL) outcome measures are becoming increasingly popular. These measures are important because complications following routine (i.e. low-risk) operations on the MV are uncommon and further markers of outcome are needed. Surgeons are increasingly operating earlier on asymptomatic patients and will need to prove that HRQOL is not impacted...
October 20, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27796866/percutaneous-mitral-valve-repair-with-mitraclip-patient-and-valve-selection-for-optimal-outcome
#12
REVIEW
Devdas T Inderbitzin, Maurizio Taramasso, Fabian Nietlispach, Francesco Maisano
In the real world of mitral regurgitation, the patient selection process for MitraClip (Abbott, Abbott Park, IL, USA) to achieve optimal outcome has become a challenge. With the opening of the Endovascular Valve Edge-to-Edge Repair Study criteria, the implant experience was extended towards functional mitral regurgitation and anatomically more complex mitral pathologies in many centers worldwide. We provide a review of the current literature to identify an appropriate patient selection process for MitraClip therapy and suggest a simple two-dimensional decision-making algorithm...
December 2016: Current Cardiology Reports
https://www.readbyqxmd.com/read/27774964/single-center-experience-with-percutaneous-mitral-valve-repair-using-the-mitraclip-in-a-high-risk-series-in-turkey
#13
Cüneyt Toprak, Gökhan Kahveci, Alev Kılıçgedik, Cevat Kırma, Selçuk Pala, Mustafa Bulut, Cihangir Kaymaz, Nihal Özdemir, İbrahim Akın İzgi, Mehmet İnanır, Anıl Avcı, Ali Metin Esen
OBJECTIVE: Mitral valve regurgitation (MR) is the second most common heart valve disease in Europe. Without intervention, prognosis of severe symptomatic MR is poor. Percutaneous edge-to-edge mitral valve repair with MitraClip is a promising mitral regurgitation treatment technique in select, high-surgical-risk patients. The present objective was to describe the experience of a single center with MitraClip use in a high-risk series in Turkey. METHODS: Between May 2013 and September 2014, 28 high-surgical-risk patients with MR of at least grade 3+ and mean EuroSCORE of 26% underwent MitraClip implantation at our institution...
October 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27753604/mitral-annular-calcification-is-not-associated-with-decreased-procedural-success-durability-of-repair-or-left-ventricular-remodelling-in-percutaneous-edge-to-edge-repair-of-mitral-regurgitation
#14
Richard Cheng, Emily Tat, Robert J Siegel, Reza Arsanjani, Asma Hussaini, Moody Makar, Yukiko Mizutani, Alfredo Trento, Saibal Kar
AIMS: Mitral annular calcification (MAC) negatively influences outcomes in surgical mitral valve (MV) repair for mitral regurgitation (MR). However, there are no data on whether MAC impacts on outcomes of MitraClip percutaneous MV edge-to-edge repair. This study sought to investigate whether the presence of MAC impacts on the procedural success and durability of percutaneous transcatheter repair of MR using the MitraClip. METHODS AND RESULTS: One hundred and seventy-three patients undergoing MitraClip repair for significant MR were studied...
October 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27752761/impact-of-cardiac-comorbidities-on-early-and-1-year-outcome-after-percutaneous-mitral-valve-interventions-data-from-the-german-transcatheter-mitral-valve-interventions-trami-registry
#15
Carsten Schwencke, Klaudija Bijuklic, Taoufik Ouarrak, Edith Lubos, Wolfgang Schillinger, Björn Plicht, Holger Eggebrecht, Stephan Baldus, Gerhard Schymik, Peter Boekstegers, Rainer Hoffmann, Jochen Senges, Joachim Schofer
AIMS: The use of the MitraClip system has gained widespread acceptance for the treatment of patients with mitral regurgitation (MR) who are not suitable for the conventional surgery. This study sought to investigate the early and 1-year outcome after MitraClip therapy of patients with MR and cardiac comorbidities. METHODS AND RESULTS: Outcomes through 12-month follow-up of patients (n = 528) who underwent MitraClip implantation were obtained from the German transcatheter mitral valve interventions (TRAMI) registry...
October 17, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27721218/not-for-adults-only-mitraclip-use-in-a-paediatric-patient
#16
Denise C Joffe, Thomas K Jones, Mark Reisman, Elizabeth Perpetua, Yuk Law, Andreas Schuler, G Burkhard Mackensen
We present the primary report of a paediatric patient who had placement of the MitraClip device for severe functional mitral regurgitation. The patient was a 14-year-old boy with symptomatic end-stage non-compaction type cardiomyopathy secondary to a mitochondrial cytopathy. He had severe mitral regurgitation, tricuspid valve regurgitation, a severely dilated LV with apical non-compaction, severe LV dysfunction and severe pulmonary hypertension. Despite optimal medical therapy he developed progressive symptoms of congestive heart failure and he was not a candidate for an assist device or cardiac transplantation...
October 10, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27710781/percutaneous-mitral-valve-repair-with-the-mitraclip-system-in-the-elderly-one-year-outcomes-from-the-grasp-registry
#17
Salvatore Scandura, Piera Capranzano, Anna Caggegi, Carmelo Grasso, Giuseppe Ronsivalle, Sarah Mangiafico, Yohei Ohno, Guilherme F Attizzani, Stefano Cannata, Sandra Giaquinta, Silvia Farruggio, Margherita Ministeri, Fabio Dipasqua, Anna M Pistritto, Sebastiano Immè, Davide Capodanno, Maria Elena Di Salvo, Corrado Tamburino
BACKGROUND: Although mitral regurgitation (MR) affects a relevant and increasing number of elderly, an optimal management of this high-risk population is challenging. METHODS AND RESULTS: The aim of this prospective, observational study was to compare one-year outcomes of MitraClip therapy in high surgical risk patients with moderate-to-severe or severe MR between patients aged <75 versus ≥75years. A total of 180 patients were included: 92 were <75years and 88 were ≥75years old...
December 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27660576/the-evolving-role-of-percutaneous-mitral-valve-repair
#18
REVIEW
Merrill H Stewart, J Stephen Jenkins
BACKGROUND: Mitral regurgitation (MR) is the second leading cause of valvular heart disease in the United States behind aortic stenosis. The percutaneous repair of the mitral valve (MitraClip, Abbott, Inc.) has been approved in the United States since 2013 as an alternative to traditional mitral valve surgery. However, many questions are left unanswered about when to perform this procedure and whom to perform it on. METHODS: We reviewed major published literature on the MitraClip from 2003-2016 to help guide clinical decision-making...
2016: Ochsner Journal
https://www.readbyqxmd.com/read/27591693/atrial-septal-defect-closure-for-right-to-left-shunting-following-a-mitraclip-repair
#19
Subhi J Al'Aref, Geoffrey Bergman, S Chiu Wong
Percutaneous repair of the mitral valve has been widely adopted for the treatment of primary, symptomatic severe mitral regurgitation in patients at prohibitive risk for surgical intervention. We present a case of an elderly female patient with moderate-to-severe mitral regurgitation who underwent MitraClip procedure, with postprocedural course remarkable for the development of right-to-left shunting and hypoxia, for which the patient underwent a percutaneous repair of the atrial septal defect with immediate recovery of oxygen saturation...
September 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27561163/right-ventricular-evaluation-to-improve-survival-outcome-in-patients-with-severe-functional-mitral-regurgitation-and-advanced-heart-failure-undergoing-mitraclip-therapy
#20
Cristina Giannini, Francesca Fiorelli, Antonio Colombo, Marco De Carlo, Sara Hana Weisz, Eustachio Agricola, Cosmo Godino, Fausto Castriota, Paolo Golino, Anna Sonia Petronio
BACKGROUND: Percutaneous mitral valve repair (PMVR) is a new option for high risk patients with functional mitral regurgitation (FMR) and severely depressed left ventricular (LV) function who are not responding to optimal medical therapy. However patients with end stage heart failure have a high mortality rate despite MitraClip implantation. We sought to identify right ventricular (RV) echocardiographic predictors of outcome in a large cohort of patients with severe FMR and advanced heart failure in order to select the most appropriate candidate who could benefit from this treatment...
November 15, 2016: International Journal of Cardiology
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