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Mitraclip, percutaneous mitral valve

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https://www.readbyqxmd.com/read/28185701/immediate-increase-of-cardiac-output-after-percutaneous-mitral-valve-repair-pmvr-determined-by-echocardiographic-and-invasive-parameters-patzelt-increase-of-cardiac-output-after-pmvr
#1
Johannes Patzelt, Yingying Zhang, Harry Magunia, Rezo Jorbenadze, Michal Droppa, Miriam Ulrich, Shanglang Cai, Henning Lausberg, Tobias Walker, Tobias Wengenmayer, Peter Rosenberger, Juergen Schreieck, Peter Seizer, Meinrad Gawaz, Harald F Langer
BACKGROUND: Successful percutaneous mitral valve repair (PMVR) in patients with severe mitral regurgitation (MR) causes changes in hemodynamics. Echocardiographic calculation of cardiac output (CO) has not been evaluated in the setting of PMVR, so far. Here we evaluated hemodynamics before and after PMVR with the MitraClip system using pulmonary artery catheterization, transthoracic (TTE) and transesophageal (TEE) echocardiography. METHODS: 101 patients with severe MR not eligible for conventional surgery underwent PMVR...
January 26, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28185355/catheter-ablation-of-ventricular-tachycardia-in-patients-with-mitraclip-device-preliminary-findings
#2
Laurent M Haegeli, Giuseppe D'Angelo, Nicola Trevisi, Stefano Stella, Alexander Breitenstein, Firat Duru, Corinna Brunckhorst, Paolo Della Bella
INTRODUCTION: Patients with mitral regurgitation are increasingly treated by percutaneous implantation of a MitraClip device. We investigate the feasibility and safety of the transmitral catheter route for catheter ablation of VT (ventricular tachycardia) in these patients. METHODS: The mitral valve with the MitraClip in situ was crossed under transesophageal three-dimensional echocardiographic and fluoroscopic guidance using a steerable sheath for ablation of the left ventricle...
February 10, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28163835/one-year-outcome-of-percutaneous-mitral-valve-repair-in-patients-with-severe-symptomatic-mitral-valve-regurgitation
#3
Michael Gotzmann, Isabell Sprenger, Aydan Ewers, Andreas Mügge, Leif Bösche
AIM: To investigate one-year outcomes after percutaneous mitral valve repair with MitraClip(®) in patients with severe mitral regurgitation (MR). METHODS Our study investigated consecutive patients with symptomatic severe MR who underwent MitraClip(®) implantation at the University Hospital Bergmannsheil from 2012 to 2014. The primary study end-point was all-cause mortality. Secondary end-points were degree of MR and functional status after percutaneous mitral valve repair. RESULTS: The study population consisted of 46 consecutive patients (mean logistic EuroSCORE 32% ± 21%)...
January 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28117279/first-percutaneous-micra-leadless-pacemaker-implantation-and-tricuspid-valve-repair-with-mitraclip-nt-for-lead-associated-severe-tricuspid-regurgitation
#4
Gilbert H L Tang, Ryan Kaple, Martin Cohen, Tanya Dutta, Cenap Undemir, Hasan Ahmad, Angelica Poniros, Joanne Bennett, Cheng Feng, Steven Lansman
AIMS: Pacemaker lead-associated severe tricuspid regurgitation (TR) can lead to right heart failure and poor prognosis. Surgery in these patients carries significant morbidities. We describe a successful treatment of symptomatic severe TR by leadless pacemaker implantation followed by tricuspid valve (TV) repair with the MitraClip NT. METHODS AND RESULTS: A 71-year-old frail female with poor functional status, chronic atrial fibrillation and permanent pacemaker implantation in 2012 presented with symptomatic moderate-severe mitral regurgitation (MR) and severe TR with the pacemaker lead as the culprit...
February 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28112459/deep-sedation-vs-general-anesthesia-in-232-patients-undergoing-percutaneous-mitral-valve-repair-using-the-mitraclip-%C3%A2-system
#5
Patrick Horn, Katharina Hellhammer, Michael Minier, Monika A Stenzel, Verena Veulemans, Tienush Rassaf, Peter Luedike, Julia Pohl, Jan Balzer, Tobias Zeus, Malte Kelm, Ralf Westenfeld
OBJECTIVES: To investigate in a series of 232 patients whether the MitraClip(®) procedure can be performed safely using deep sedation (DS) without general anesthesia (GA). BACKGROUND: Transcatheter mitral valve repair using the MitraClip(®) system is a safe and effective therapy for severe mitral regurgitation (MR) in patients who are at high operative risk or are unsuitable for surgery. For these patients, avoidance of GA might be beneficial. METHODS: Between 2011 and 2015, we performed 232 MitraClip(®) procedures for the treatment of severe MR...
January 23, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28069638/feasibility-and-predictors-of-early-discharge-after-percutaneous-edge-to-edge-mitral-valve-repair
#6
Corrado Tamburino, Sergio Buccheri, Antonio Popolo Rubbio, Salvatore Scandura, Maria Elena Di Salvo, Sarah Mangiafico, Sebastiano Immé, Giuseppe Caruso, Matteo Scalia, Antonio Condorelli, Marco Barbanti, Piera Capranzano, Davide Capodanno, Carmelo Grasso
BACKGROUND: Percutaneous edge-to-edge mitral valve repair (PMVR) recently emerged as an effective treatment modality for patients with severe mitral regurgitation (MR). Length of postprocedural hospital stay may represent a modifiable cost associated with percutaneous treatment. We looked at feasibility, predictors and safety of early discharge (ED), defined as hospital discharge within 72 hours, in patients undergoing PMVR. METHODS AND RESULTS: Consecutive patients treated with MitraClip from October 2008 to December 2015 were analysed...
January 9, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27989042/mitraclip%C3%A2-two-weeks-after-implantation
#7
Juliëtte F Velu, Hans H de Boer, Berto J Bouma, Jan Baan
A 73-year-old male received a percutaneous mitral valve repair with a MitraClip to treat severe (grade IV) symptomatic mitral regurgitation (MR). The MitraClip® procedure reduced the MR to grade I, but the patient died 14 days post-procedurally due to a pneumosepsis. Histological analysis of the MitraClip mesh covering showed a chronic inflammatory reaction with an abundance of multinucleated giant cells. Remarkably, signs of early onset clip-coverage were found, indicated by the presence of a few scattered myofibroblasts...
May 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27989041/left-atrial-and-left-ventricular-function-and-remodeling-following-percutaneous-mitral-valve-repair
#8
Christos Rammos, Tobias Zeus, Jan Balzer, Verena Veulemans, Katharina Hellhammer, Svenja Niebel, Malte Kelm, Tienush Rassaf
BACKGROUND: Mitral regurgitation causes left atrial (LA) and left ventricular (LV) dysfunction, dilatation, and remodeling. Following percutaneous mitral valve repair (PMVR) using the MitraClip® approach, reverse cardiac remodeling is desirable. To date, the influence of PMVR on LA and segmental LV function and remodeling has not been investigated in detail. METHODS: Twenty-six patients who received the MitraClip device were enrolled in an open-label, single-center observational study...
May 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27987271/previous-malignancy-is-an-independent-predictor-of-follow-up-mortality-after-percutaneous-treatment-of-mitral-valve-regurgitation-by-means-of-mitraclip
#9
Alper Öner, Hüseyin Ince, Liliya Paranskaya, Guido Schröder, Mohammad Sherif, Olga Thiele, Alla Neuhausen, Kische Stephan, Jasmin Ortak, Giuseppe D Ancona
AIMS: To investigate the prognostic burden of previously diagnosed and treated malignancies in candidates for percutaneous mitral valve repair (MVR) with MitraClip. METHODS AND RESULTS: A total of 165 patients underwent MVR and 19 (11.5%) had been previously treated for malignancy and considered healed with life expectancy over 1 year at time of percutaneous MVR. There was a significant trend for an increased overall risk profile (euroSCORE II 14.0±11.4 vs. 10...
December 16, 2016: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/27964904/immediate-and-12-month-outcomes-of-ischemic-versus-nonischemic-functional-mitral-regurgitation-in-patients-treated-with-mitraclip-from-the-2011-to-2012-pilot-sentinel-registry-of-percutaneous-edge-to-edge-mitral-valve-repair-of-the-european-society-of-cardiology
#10
Michele Pighi, Rodrigo Estevez-Loureiro, Francesco Maisano, Gian P Ussia, Gianni Dall'Ara, Olaf Franzen, Cécile Laroche, Magnus Settergren, Reidar Winter, Georg Nickenig, Martine Gilard, Carlo Di Mario
In literature, there are limited data comparing ischemic mitral regurgitation (I-MR) versus nonischemic MR regarding outcomes after percutaneous "edge-to-edge" repair. We aimed to describe the early and 12-month results after MitraClip device implantation regarding the 2 etiologies. From January 2011 to December 2012, the Transcatheter Valve Treatment Sentinel Pilot Registry included 452 patients with MR who underwent MitraClip procedure in 25 centers across Europe. The prevalent etiology was I-MR (235 patients, 52...
February 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/27933588/mitraclip-step-by-step-how-to-simplify-the-procedure
#11
REVIEW
M A Sherif, L Paranskaya, S Yuecel, S Kische, O Thiele, G D'Ancona, A Neuhausen-Abramkina, J Ortak, H Ince, A Öner
The MitraClip system is a device for percutaneous edge-to-edge reconstruction of the mitral valve in patients with severe mitral regurgitation who are deemed at high risk for surgery. Studies have underlined the therapeutic benefit of the MitraClip system for patients at extreme and high risk for mitral valve surgery, suffering from either degenerative or functional mitral regurgitation. The MitraClip procedure shows low peri-procedural complication rates, and a significant reduction in mitral regurgitation, as well as an improvement in functional capacity and most importantly quality of life...
February 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27875721/percutaneous-mitral-valve-repair-the-last-chance-for-symptoms-improvement-in-advanced-refractory-chronic-heart-failure
#12
Alessandra Berardini, Elena Biagini, Francesco Saia, Davide Stolfo, Mario Previtali, Francesco Grigioni, Bruno Pinamonti, Gabriele Crimi, Alessandro Salvi, Maurizio Ferrario, Antonio De Luca, Fabrizio Gazzoli, Maria Letizia Bacchi Reggiani, Claudia Raineri, Gianfranco Sinagra, Claudio Rapezzi
BACKGROUND: The role of percutaneous mitral valve repair (PMVR) in patients with end-stage heart failure (HF) and functional mitral regurgitation (FMR) is unclear. METHODS: Seventy-five consecutive patients with FMR grade≥3+ and severe HF symptoms despite optimal medical therapy and resynchronization therapy underwent PMVR with the MitraClip system (Abbott, Abbott Park, IL, USA) at 3 centers. Clinical evaluation, echocardiography and pro-BNP measurement were performed at baseline and at 6-month...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27860182/from-tricuspid-to-double-orifice-morphology-percutaneous-tricuspid-regurgitation-repair-with-the-mitraclip-device-in-congenitally-corrected-transposition-of-great-arteries
#13
Fabien Picard, Victor-Xavier Tadros, Anita W Asgar
Edge to edge transcatheter mitral valve repair with MitraClip (Abbott Vascular, Menlo Park, CA) is increasing for high-risk surgical patients with significant mitral regurgitation. Patients with congenitally corrected transposition of the great arteries (CCTGA) presenting with tricuspid valve regurgitation of a systemic right ventricle may represent particularly challenging candidates for MitraClip given their anatomy. We report the case of a 67-year-old gentleman with CCTGA and severe tricuspid regurgitation who was referred for MitraClip implantation after heart team consensus...
November 10, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27852483/mitraclip-therapy-for-mitral-regurgitation-primary-mitral-regurgitation
#14
REVIEW
G Athappan, Mohammad Qasim Raza, Samir R Kapadia
Primary mitral regurgitation (MR) owing to degenerative changes in the structural components of the mitral valve is a common acquired valvular pathology in the elderly. Surgical correction with mitral valve repair (MVRe) or replacement (MVR) is the mainstay of therapy. A significant proportion of patients are ineligible for MVRe/MVR owing to prohibitive surgical risk from advanced age, poor ventricular function, or associated comorbidities. Percutaneous mitral valve repair techniques have been developed to fill this void...
January 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/27852482/targeted-transseptal-access-for-mitraclip-percutaneous-mitral-valve-repair
#15
REVIEW
Gagan D Singh, Thomas W Smith, Jason H Rogers
Targeted transseptal puncture remains the most critical initial part of the overall MitraClip procedure. Care and attention must be implemented for patient safety in choosing the optimal puncture site. A consistent and step-by-step methodical approach is recommended. As experienced operators are targeting more complex and nontraditional pathologic conditions, use of adjunctive tools and maneuvers (outlined in this review) are paramount to achieving successful targeted transseptal access and ultimately procedural success...
January 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/27798059/quality-of-life-after-mitral-valve-intervention
#16
Matthew K H Tan, Omar A Jarral, Elizabeth H E Thong, Emaddin Kidher, Rakesh Uppal, Prakash P Punjabi, Thanos Athanasiou
Advancements in surgical technique and understanding of the pathophysiology of mitral valve (MV) dysfunction have led to improved outcomes. Seen as a development beyond measures of morbidity and mortality, health-related quality-of-life (HRQOL) outcome measures are becoming increasingly popular. These measures are important because complications following routine (i.e. low-risk) operations on the MV are uncommon and further markers of outcome are needed. Surgeons are increasingly operating earlier on asymptomatic patients and will need to prove that HRQOL is not impacted...
October 20, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27796866/percutaneous-mitral-valve-repair-with-mitraclip-patient-and-valve-selection-for-optimal-outcome
#17
REVIEW
Devdas T Inderbitzin, Maurizio Taramasso, Fabian Nietlispach, Francesco Maisano
In the real world of mitral regurgitation, the patient selection process for MitraClip (Abbott, Abbott Park, IL, USA) to achieve optimal outcome has become a challenge. With the opening of the Endovascular Valve Edge-to-Edge Repair Study criteria, the implant experience was extended towards functional mitral regurgitation and anatomically more complex mitral pathologies in many centers worldwide. We provide a review of the current literature to identify an appropriate patient selection process for MitraClip therapy and suggest a simple two-dimensional decision-making algorithm...
December 2016: Current Cardiology Reports
https://www.readbyqxmd.com/read/27774964/single-center-experience-with-percutaneous-mitral-valve-repair-using-the-mitraclip-in-a-high-risk-series-in-turkey
#18
Cüneyt Toprak, Gökhan Kahveci, Alev Kılıçgedik, Cevat Kırma, Selçuk Pala, Mustafa Bulut, Cihangir Kaymaz, Nihal Özdemir, İbrahim Akın İzgi, Mehmet İnanır, Anıl Avcı, Ali Metin Esen
OBJECTIVE: Mitral valve regurgitation (MR) is the second most common heart valve disease in Europe. Without intervention, prognosis of severe symptomatic MR is poor. Percutaneous edge-to-edge mitral valve repair with MitraClip is a promising mitral regurgitation treatment technique in select, high-surgical-risk patients. The present objective was to describe the experience of a single center with MitraClip use in a high-risk series in Turkey. METHODS: Between May 2013 and September 2014, 28 high-surgical-risk patients with MR of at least grade 3+ and mean EuroSCORE of 26% underwent MitraClip implantation at our institution...
October 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27753604/mitral-annular-calcification-is-not-associated-with-decreased-procedural-success-durability-of-repair-or-left-ventricular-remodelling-in-percutaneous-edge-to-edge-repair-of-mitral-regurgitation
#19
Richard Cheng, Emily Tat, Robert J Siegel, Reza Arsanjani, Asma Hussaini, Moody Makar, Yukiko Mizutani, Alfredo Trento, Saibal Kar
AIMS: Mitral annular calcification (MAC) negatively influences outcomes in surgical mitral valve (MV) repair for mitral regurgitation (MR). However, there are no data on whether MAC impacts on outcomes of MitraClip percutaneous MV edge-to-edge repair. This study sought to investigate whether the presence of MAC impacts on the procedural success and durability of percutaneous transcatheter repair of MR using the MitraClip. METHODS AND RESULTS: One hundred and seventy-three patients undergoing MitraClip repair for significant MR were studied...
October 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27752761/impact-of-cardiac-comorbidities-on-early-and-1-year-outcome-after-percutaneous-mitral-valve-interventions-data-from-the-german-transcatheter-mitral-valve-interventions-trami-registry
#20
Carsten Schwencke, Klaudija Bijuklic, Taoufik Ouarrak, Edith Lubos, Wolfgang Schillinger, Björn Plicht, Holger Eggebrecht, Stephan Baldus, Gerhard Schymik, Peter Boekstegers, Rainer Hoffmann, Jochen Senges, Joachim Schofer
AIMS: The use of the MitraClip system has gained widespread acceptance for the treatment of patients with mitral regurgitation (MR) who are not suitable for the conventional surgery. This study sought to investigate the early and 1-year outcome after MitraClip therapy of patients with MR and cardiac comorbidities. METHODS AND RESULTS: Outcomes through 12-month follow-up of patients (n = 528) who underwent MitraClip implantation were obtained from the German transcatheter mitral valve interventions (TRAMI) registry...
October 17, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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