keyword
Keywords Mitraclip, percutaneous mitral...

Mitraclip, percutaneous mitral valve

https://read.qxmd.com/read/38529422/advancements-in-mitraclip-intervention-for-mitral-regurgitation-a-comprehensive-review-and-comparative-analysis-of-clinical-trials
#1
REVIEW
Shitij Shrivastava, Shashwat Shrivastava, Sai Vishnu Vardhan Allu, Patrik Schmidt, Moiud Mohyeldin, Abeer Qasim
This comprehensive review explores the evolution and clinical impact of MitraClip intervention in the management of mitral regurgitation. Mitral regurgitation results from dysfunction in the mitral valve (MV) apparatus. The MitraClip Clip Delivery System was approved by the Food and Drug Administration (FDA) in 2013. The discussion delves into the procedural foundation of MitraClip intervention, primarily based on Alfieri's technique of edge-to-edge leaflet approximation. As highlighted by key clinical trials, including Endovascular Valve Edge-to-Edge Repair (EVEREST) II Trial, Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) Trial, and Percutaneous Repair with the MitraClip Device for Severe Functional/Secondary Mitral Regurgitation (MITRA-FR) trial, the efficacy and safety of MitraClip were evaluated in comparison to surgical interventions and guideline-directed medical therapy...
February 2024: Curēus
https://read.qxmd.com/read/38515335/long-term-cost-effectiveness-of-transcatheter-mitral-valve-repair-in-%C3%A2-hf-patients-with-secondary-mitral-regurgitation
#2
JOURNAL ARTICLE
Younan Yao, Ziyou Zhou, Tian Geng, Anping Cai, Tian Li, Junqing Yang, Jiyan Chen, Liwen Li
AIMS: The long-term cost-effectiveness of MitraClip in heart failure patients with secondary mitral regurgitation is still unclear. This study aimed to evaluate the long-term cost-effectiveness of MitraClip added to guideline-directed medical therapy vs. guideline-directed medical therapy alone in heart failure patients with secondary mitral regurgitation from the perspective of the healthcare systems of mainland China, the United Kingdom, Germany, and the United States. METHODS AND RESULTS: A two-stage (decision + Markov) model was built...
March 22, 2024: ESC Heart Failure
https://read.qxmd.com/read/38391273/a-deep-dive-into-the-percutaneous-mitral-valve-data
#3
JOURNAL ARTICLE
Ana Paula Tagliari, Rodrigo Petersen Saadi, Gilbert H L Tang
PURPOSE OF REVIEW: This review offers insights into percutaneous mitral valve management, emphasizing pivotal trials that contributed to its evolution. RECENT FINDINGS: Mitral regurgitation (MR) is a highly prevalent heart valve disease, with surgical intervention being the gold standard for managing primary MR. However, a notable proportion of patients face ineligibility criteria or are at high surgical risk, particularly in the setting of secondary MR. To fill this gap, transcatheter therapies have emerged as less invasive alternatives...
February 26, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38388247/use-of-safari-2%C3%A2-as-workhorse-wire-for-left-sided-structural-heart-interventions
#4
JOURNAL ARTICLE
Ibrahim H Inanc, Deniz Mutlu, Kostas Marmagkiolis, Cezar Iliescu, Ismail Ates, Mehmet Cilingiroglu
BACKGROUND: With the advances in percutaneous treatment technologies, the left atrial appendage occlusion (LAAO) and the transcatheter mitral valve repair using MitraClip (TMVR) are increasingly being performed today. The SAFARI 2™ guidewire is primarily used during transcatheter aortic valve implantation (TAVI), our group has also been using it during MitraClip and LAAO procedures. Our clinical study aimed to share our data on the safety and effectiveness for the use of the SAFARI 2™ guidewire during MitraClip or LAAO procedures...
February 8, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/38358418/frailty-periinterventional-complications-and-outcome-in-patients-undergoing-percutaneous-mitral-and-tricuspid-valve-repair
#5
JOURNAL ARTICLE
Matthieu Schäfer, Hannah Nöth, Clemens Metze, Christos Iliadis, Maria Isabel Körber, Marcel Halbach, Stephan Baldus, Roman Pfister
BACKGROUND: Frailty is common in elderly and multimorbid patients and associated with increased vulnerability to stressors. METHODS: In a single centre study frailty according to Fried criteria was assessed in consecutive patients before transcatheter mitral and tricuspid valve repair. Postprocedural infections, blood transfusion and bleeding and renal failure were retrospectively assessed from records. Median follow-up time for survival was 560 days (IQR: 363 to 730 days)...
February 15, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38346608/a-review-regarding-the-article-clinical-and-echocardiographic-outcomes-of-patients-undergoing-transcatheter-edge-to-edge-repair-for-functional-vs-degenerative-mitral-valve-regurgitation
#6
REVIEW
Zhen Li, Fenglin Yi, Kangxi Zuo, Gang Zhao, Bhushan Sandeep
Echocardiography is widely available in most cardiac centers, plays a key role in both the diagnosis and management of IE, is often the first-hand imaging modality, and should be performed immediately when mitral regurgitation is suspected. In addition, it is helpful during therapy and after surgery to assess valve morphology and function, complications, and heart function. In particular, transthoracic echocardiography is useful to detect new silent complications, monitor vegetation size, assess perivalvular abscess formation, pseudoaneurysm, intracardiac fistula and valvular perforation, as well as examine the embolic risk...
February 10, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38267110/transcatheter-edge-to-edge-repair-in-coapt-ineligible-patients-with-functional%C3%A2-mitral%C3%A2-regurgitation
#7
JOURNAL ARTICLE
Adnan K Chhatriwalla, David J Cohen, Sreekanth Vemulapalli, Andrew Vekstein, Chetan P Huded, Dianne Gallup, Andrzej S Kosinski, Leo Brothers, JoAnn Lindenfeld, Gregg W Stone, Paul Sorajja
BACKGROUND: Mitral valve transcatheter edge-to-edge repair (MTEER) was approved in the United States for treatment of functional mitral regurgitation (FMR) based on results from the COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) trial. OBJECTIVES: The authors sought to analyze outcomes of MTEER in FMR patients who would have been excluded from COAPT. METHODS: MTEER procedures performed for FMR in the TVT (Transcatheter Valve Therapy) Registry between January 1, 2013, and April 30, 2020, were categorized as "trial-ineligible" if any of the following were present: cardiogenic shock, inotropic support, left ventricular ejection fraction <20%, left ventricular end-systolic dimension >7 cm, home oxygen use, or severe tricuspid regurgitation...
January 30, 2024: Journal of the American College of Cardiology
https://read.qxmd.com/read/38261814/anesthesia-challenges-and-role-of-transesophageal-echocardiography-during-mitraclip-implantation-in-a-patient-with-end-stage-heart-failure
#8
Kunal Sarin, Rajat Datta, Prashant Bharadwaj, G Keshavamurthy
Patients with dilated cardiomyopathy who have developed mitral valve regurgitation (MR) with reduced left ventricular ejection fraction and are too sick to undergo any surgical repair or replacement are being treated worldwide through catheter-based percutaneous intervention techniques to treat MR like MitraClip system®. There are very few case reports especially from India on anesthetic management during MitraClip device implantation and its specific considerations. We present a case of a 48-year-old male patient, diagnosed as post-myocarditis dilated cardiomyopathy with poor left ventricular ejection fraction (30-35%) and severe MR who underwent mitral clip implantation with fluoroscopy and transesophageal echocardiography guidance under general anesthesia...
2024: Medical Journal, Armed Forces India
https://read.qxmd.com/read/38180422/first-in-human-percutaneous-excision-of-a-failed-mitraclip-followed-by-transcatheter-mitral-valve-replacement
#9
JOURNAL ARTICLE
David Elison, Gabriel Aldea, Srjdan Jelacic, Christine J Chung, G Burkhard Mackensen, James M McCabe
No abstract text is available yet for this article.
December 20, 2023: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38089119/bailout-mitraclip-therapy-for-deteriorated-systolic-anterior-motion-related-severe-mitral-regurgitation-post-alcohol-septal-ablation-a-case-report
#10
Shinsuke Nakano, Hiroyuki Yamamoto, Nobuyuki Takahashi, Tomofumi Takaya
BACKGROUND: Percutaneous alcohol septal ablation (ASA) is a non-surgical treatment for symptomatic hypertrophic obstructive cardiomyopathy. It has a potential risk for systolic anterior motion (SAM)-related mitral regurgitation (MR) deterioration, leading to acute congestive heart failure. In such clinical scenarios, additional surgical interventions for SAM-MR are risky. CASE SUMMARY: A 70-year-old man experienced acutely deteriorated heart failure caused by SAM-related MR following ASA, for which venous-arterial extracorporeal membrane oxygenation (ECMO) and a percutaneous left ventricular assist device (Impella CP, Abiomed, MA, USA) were required...
December 2023: European Heart Journal. Case Reports
https://read.qxmd.com/read/38068282/sex-specific-disparities-in-outcomes-of-transcatheter-edge-to-edge-repair-for-mitral-regurgitation-a-multicenter-real-world-analysis
#11
JOURNAL ARTICLE
Felix Ausbuettel, Sebastian Barth, Georgios Chatzis, Kiarash Sassani, Dieter Fischer, Sebastian Weyand, Julian Mueller, Harald Schuett, Bernhard Schieffer, Ulrich Luesebrink, Christian Waechter
BACKGROUND: mitral regurgitation (mr) is the most common valvular heart disease (vhd) in the elderly and tends to be more prevalent in women. while relevant sex differences in outcomes are evident in surgically treated collectives, there are very limited and conflicting sex-specific data for the growing cohort of patients undergoing transcatheter edge-to-edge repair (teer). OBJECTIVE: to investigate whether sex impacts procedural safety and efficacy, and in-hospital- and long-term outcomes, after teer for mr...
November 22, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38050305/case-report-transcatheter-edge-to-edge-repair-with-mitraclip-for-acute-mitral-regurgitation-after-myocardial-infarction
#12
JOURNAL ARTICLE
Fan-Qi Meng, Bin Wang, Xiang Chen, Mao-Long Su, Peng-Long Wu, Yan Wang
INTRODUCTION: Acute mitral regurgitation (MR) due to papillary muscle rupture (PMR) is a rare but lethal mechanical complication of acute myocardial infarction (MI). The treatment of patients with post-MI PMR, especially those with cardiogenic shock, presents great challenges due to the high surgical risk. PATIENT CONCERNS: We report an 80-year-old woman with a history of hypertension and diabetes mellitus, presented with chest pain. Despite an early percutaneous coronary intervention and transfer to the intensive care unit, her general condition and hemodynamic parameters continued to deteriorate rapidly...
December 1, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/38002733/contemporary-echocardiographic-evaluation-of-mitral-regurgitation-and-guidance-for-percutaneous-mitral-valve-repair
#13
REVIEW
Davide Marchetti, Francesca Di Lenarda, Maria Laura Novembre, Pasquale Paolisso, Matteo Schillaci, Eleonora Melotti, Marco Doldi, Riccardo Terzi, Michele Gallazzi, Edoardo Conte, Valentina Volpato, Antonio Bartorelli, Daniele Andreini
Mitral valve regurgitation (MR) is a multifaceted valvular heart disease. Echocardiography plays a central role in etiology assessment, severity quantification, treatment candidacy, outcome evaluation, and patient follow-up. In this review, we describe the comprehensive echocardiographic assessment of MR, including transthoracic (TTE) and transesophageal (TEE) approaches, 2D and 3D modalities, strain imaging, stress echocardiography, and artificial intelligence (AI) applications. Transcatheter edge-to-edge mitral valve repair (TEER) has been established as a key therapy for patients with severe, symptomatic MR and high surgical risk...
November 15, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37741106/percutaneous-mitral-valve-repair-for-secondary-mitral-regurgitation-a-systematic-review-and-meta-analysis
#14
REVIEW
Rasha Kaddoura, Sanket Bhattarai, Dina Abushanab, Mohammed Al-Hijji
This systematic review and meta-analysis aimed to investigate whether percutaneous mitral valve repair (PMVr) using MitraClip was more effective than surgery or medical therapy for long-term morbidity and mortality. We searched MEDLINE, EMBASE, and CENTRAL (Cochrane Library) databases to identify relevant studies that recruited adult patients with functional or secondary mitral valve regurgitation who underwent PMVr with MitraClip implantation using appropriate search terms and Boolean operators. The odds ratios (ORs) were pooled using the random-effects model...
September 21, 2023: American Journal of Cardiology
https://read.qxmd.com/read/37736210/paracentral-mitraclip-implantation-technique-in-a-mitral-valve-with-a-small-area-due-to-rheumatic-change
#15
Kento Kito, Akihisa Kataoka, Hirofumi Hioki, Yusuke Watanabe, Ken Kozuma
No abstract text is available yet for this article.
September 2023: AsiaIntervention
https://read.qxmd.com/read/37730395/one-year-real-world-outcomes-for-patients-undergoing-transcatheter-mitral-valve-repair-the-gulf-mteer-registry-gulf-mitral-transcatheter-edge-to-edge-repair
#16
MULTICENTER STUDY
Mirvat Alasnag, Fayez Bokhari, Abdulrahman Almoghairi, Khaled Marri, Abdullah Alenezi, Waleed AlHarbi, Nouf Alanazi, Haitham Amin, Hussam Noor, Shereen Al-Shaikh, Fawaz Bardowli, Hatim Al Lawati, Khalid AlFaraidy, Mohammed AlShehri, Adel Tash, Waleed AlHabeeb, Mohammed Balghith, Michael Thabane, Lehana Thabane, Khaled Al-Shaibi
BACKGROUND: Severe mitral regurgitation (MR) with left ventricular dysfunction portends worse outcomes. Over the course of the last two decades, transcatheter repair of the mitral valve offered an alternative therapeutic modality for those deemed inoperable or high risk. Landmark studies such as the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation and Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation trials have shown conflicting results with respect to all-cause death and heart failure rehospitalisations...
September 20, 2023: BMJ Open
https://read.qxmd.com/read/37730284/transcatheter-edge-to-edge-repair-in-5-000-patients-with-secondary-mitral%C3%A2-regurgitation-coapt-post-approval-study
#17
MULTICENTER STUDY
Kashish Goel, JoAnn Lindenfeld, Raj Makkar, Hursh Naik, Satya Atmakuri, Paul Mahoney, Michael A Morse, Vinod H Thourani, Pradeep Yadav, Wayne Batchelor, Jason Rogers, Brian Whisenant, Michael Rinaldi, James Hermiller, Brian R Lindman, Colin M Barker
BACKGROUND: Real-world applicability of the COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) randomized controlled trial (RCT) has been debated because of careful patient selection and the contrasting results of the MITRA-FR (Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients with Severe Secondary Mitral Regurgitation) RCT. OBJECTIVES: The COAPT-PAS (COAPT Post-Approval Study) was initiated to assess the safety and effectiveness of the MitraClip in patients with secondary mitral regurgitation (SMR)...
September 26, 2023: Journal of the American College of Cardiology
https://read.qxmd.com/read/37611988/mitral-interventions-in-heart%C3%A2-failure
#18
REVIEW
Matthew M Lander, Michael I Brener, Kashish Goel, Paul C Tang, Nathan J Verlinden, Sandip Zalawadiya, JoAnn Lindenfeld, Manreet K Kanwar
Patients with heart failure with reduced ejection fraction who have secondary mitral regurgitation (SMR) have poorer outcomes and quality of life than those without SMR. Guideline-directed medical therapy is the cornerstone of SMR treatment. Careful evaluation of landmark trials using mitral transcatheter edge-to-edge repair in SMR has led to an improved understanding of who will benefit from percutaneous interventions with emphasis on a multidisciplinary approach. The success with mitral transcatheter edge-to-edge repair in SMR has also spurred the evaluation of its role in populations that were not initially studied, such as end-stage heart failure and cardiogenic shock...
August 2023: JACC. Heart Failure
https://read.qxmd.com/read/37601732/transcatheter-mitral-valve-repair-via-mitraclip-in-patients-aged-65-years-multicentre-2-year-outcomes
#19
JOURNAL ARTICLE
Hassan Mh Mohammed, Ahmed Farah, Bjoern Plicht, Mohammad El-Garhy, Ilse Janicke, Amr Yousef, Mohammad Abdelkader AbdelWahab, Nasser M Taha, Wolfgang Schoels, Thomas Buck
BACKGROUND: Transcatheter mitral valve repair (TMVR) using the MitraClip has become a well-established interventional therapy and is usually performed in elderly patients. The objective of this study was to assess 2-year clinical outcomes of TMVR in patients aged <65 years at three heart centres with severe mitral regurgitation (MR) and no surgical options. METHODS: A retrospective study analysed data of 36 patients aged <65 years treated with TMVR . All patients were refused surgery by Heart Team decision...
2023: Interventional Cardiology
https://read.qxmd.com/read/37584023/acute-mitral-regurgitation-with-unilateral-left-sided-pulmonary-edema-a-complication-of-stemi-treated-successfully-with-a-mitraclip-procedure
#20
Ibrar Anjum, Umer Zia, Sheraz Anjum, Shalin Patel
A 67-year-old man with inferior wall ST-segment elevation myocardial infarction underwent Impella-assisted percutaneous coronary intervention complicated by unilateral left-sided pulmonary edema and cardiogenic shock due to severe mitral valve regurgitation. Surgery was deferred due to hemodynamic instability and a high risk of mortality, so he underwent a MitraClip procedure. Mitral regurgitation (MR) is a catastrophic mechanical complication of myocardial infarction that leads to the development of pulmonary edema, cardiogenic shock, and death...
2023: Heart Views: the Official Journal of the Gulf Heart Association
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