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https://www.readbyqxmd.com/read/28921386/midterm-outcomes-of-two-staged-hybrid-ablation-of-persistent-and-long-standing-persistent-atrial-fibrillation-using-the-versapolar-epicardial-surgical-device-and-subsequent-catheter-ablation
#1
Petr Budera, Pavel Osmancik, Dalibor Herman, Jana Zdarska, David Talavera, Anna Mala, Radka Prochazkova, Zbynek Straka
PURPOSE: Hybrid ablation of atrial fibrillation (AF) is a promising treatment strategy for patients with non-paroxysmal AF, although, data regarding mid-term outcomes are limited. METHODS: Patients with persistent or long-standing persistent AF were enrolled. Initially, a thoracoscopic, right-sided, epicardial ablation was performed, with a goal of creating a box lesion on the posterior wall of the left atrium; a novel versapolar radiofrequency (RF) catheter was used...
September 18, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28918212/an-%C3%AE-glucosidase-inhibitor-could-reduce-t-wave-alternans-in-type-2-diabetes-patients
#2
Kazuo Eguchi, Takahiro Komori, Toshinobu Saito, Satoshi Hoshide, Kazuomi Kario
BACKGROUND: We tested the hypothesis that an alpha-glucosidase inhibitor (α-GI), miglitol, is effective in protecting the cardiovascular system in type 2 diabetes mellitus (T2DM). METHODS: We studied 19 hospitalized heart disease patients with T2DM in whom we performed continuous glucose monitoring, Holter electrocardiogram, and ambulatory blood pressure (BP) monitoring simultaneously for 48h. The α-GI miglitol was administered for half of the study period by a cross-over fashion...
August 15, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28904084/relevance-of-supraventricular-runs-detected-after-cerebral-ischemia
#3
Mark Weber-Krüger, Constanze Lutz, Antonia Zapf, Raoul Stahrenberg, Joachim Seegers, Janin Witzenhausen, Katrin Wasser, Gerd Hasenfuß, Klaus Gröschel, Rolf Wachter
OBJECTIVE: Prolonged ECG monitoring after stroke frequently reveals short paroxysmal atrial fibrillation (pAF) and supraventricular (SV) runs. The minimal duration of atrial fibrillation (AF) required to induce cardioembolism, the relevance of SV runs, and whether short pAF results from cerebral damage itself are currently being debated. We aimed to study the relevance of SV runs and short pAF detected by prolonged Holter ECG after cerebral ischemia during long-term follow-up. METHODS: Analysis is from the prospective Find-AF trial (ISRCTN46104198)...
September 13, 2017: Neurology
https://www.readbyqxmd.com/read/28893430/excessive-atrial-ectopic-activity-as-an-independent-risk-factor-for-ischemic-stroke
#4
Rita Marinheiro, Leonor Parreira, Pedro Amador, Catarina Sá, Tatiana Duarte, Rui Caria
BACKGROUND: Excessive atrial ectopic activity (EAEA) has been related with an increased risk of atrial fibrillation (AF) and stroke but different cutoff values have been used. We aimed to determine the association between EAEA and stroke, AF and overall death. METHODS: Consecutive 24-hour Holter monitoring performed between 2005 and 2010 in a single center was evaluated. Patients with a previous diagnosis of stroke or AF were excluded. The number of premature atrial contractions (PACs) during 24h was analyzed in 2480 subjects and according to that 3 sub-groups were defined: >97PACs/h (above the top 5th percentile of the population) (EAEA+); intermediate value of PACs/h (below the top 5th percentile but above 30PACs/h) (EAEA+/-) and <30PACs/h (EAEA-)...
August 26, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28884653/smartphone-electrographic-monitoring-for-atrial-fibrillation-in-acute-ischemic-stroke-and-transient-ischemic-attack
#5
Hans T Tu, Ziyuan Chen, Corey Swift, Leonid Churilov, Ruibing Guo, Xinfeng Liu, Jim Jannes, Vincent Mok, Ben Freedman, Stephen M Davis, Bernard Yan
Rationale Paroxysmal atrial fibrillation is a common and preventable cause of devastating strokes. However, currently available monitoring methods, including Holter monitoring, cardiac telemetry and event loop recorders, have drawbacks that restrict their application in the general stroke population. AliveCor™ heart monitor, a novel device that embeds miniaturized electrocardiography (ECG) in a smartphone case coupled with an application to record and diagnose the ECG, has recently been shown to provide an accurate and sensitive single lead ECG diagnosis of atrial fibrillation...
October 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28865890/natriuretic-propeptides-as-markers-of-atrial-fibrillation-burden-and-recurrence-from-the-amio-cat-trial
#6
Stine Darkner, Jens Peter Goetze, Xu Chen, Kristoffer Henningsen, Steen Pehrson, Jesper Hastrup Svendsen
Natriuretic peptides are established plasma markers of systolic heart failure, but their usefulness for the evaluation of atrial fibrillation (AF) is unknown. We examined mid-regional pro-atrial natriuretic peptide (MR-proANP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients undergoing ablation for AF. A subpopulation of 102 patients (median age 60 [52;65], 82% male) from the AMIO-CAT trial (Recurrence of arrhythmia following short-term oral AMIOdarone after CATheter ablation for atrial fibrillation: a double-blind, randomized, placebo-controlled study) undergoing ablation for paroxysmal (n = 55) or persistent (n = 47) AF was studied...
July 24, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28855115/catheter-ablation-versus-medical-rate-control-in-atrial-fibrillation-and-systolic-dysfunction-camera-mri
#7
Sandeep Prabhu, Andrew J Taylor, Ben T Costello, David M Kaye, Alex Aj McLellan, Aleksandr Voskoboinik, Hariharan Sugumar, Siobhan M Lockwood, Michael B Stokes, Bhupesh Pathik, Chrishan J Nalliah, Geoff R Wong, Sonia M Azzopardi, Sarah Gutman, Geoffrey Lee, Jamie Layland, Justin A Mariani, Liang-Han Ling, Jonathan M Kalman, Peter M Kistler
BACKGROUND: Atrial fibrillation (AF) and left ventricular systolic dysfunction (LVSD) frequently co-exist despite adequate rate-control. Existing randomized studies of AF and LVSD of varying etiologies have demonstrated modest benefits with a rhythm control strategy. OBJECTIVE: To determine whether catheter ablation (CA) for AF could improve LVSD compared to medical rate-control (MRC) where the etiology of the LVSD was unexplained, apart from the presence of AF...
August 22, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28853316/effect-of-electromagnetic-field-accompanying-the-magnetic-resonance-imaging-on-human-heart-rate-variability%C3%A2-%C3%A2-a-pilot-study
#8
Arkadiusz Derkacz, Jakub Gawrys, Karolina Gawrys, Maciej Podgorski, Agnieszka Magott-Derkacz, Rafał Poreba, Adrian Doroszko
The effect of electromagnetic field on cardiovascular system in the literature is defined in ambiguous way. The aim of this study was to evaluate the effect of electromagnetic field on the heart rate variability (HRV) during the examination with magnetic resonance. Forty-two patients underwent Holter ECG heart monitoring for 30 minutes twice: immediately before and after the examination with magnetic resonance imaging (MRI). HRV was analysed by assessing a few selected time and spectral parameters. Is has been shown that standard deviation of NN intervals (SDNN) and very low frequency rates increased, whereas the low frequency:high frequency parameter significantly decreased following the MRI examination...
August 30, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28851409/mobile-phones-in-cryptogenic-stroke-patients-bringing-single-lead-ecgs-for-atrial-fibrillation-detection-mobile-af-study-protocol-for-a-randomised-controlled-trial
#9
Roderick W Treskes, Willem Gielen, Marieke J Wermer, Robert W Grauss, Anouk P van Alem, Reza Alizadeh Dehnavi, Charles J Kirchhof, Enno T van der Velde, Arie C Maan, Ron Wolterbeek, Onno M Overbeek, Martin J Schalij, Serge A Trines
BACKGROUND: Recently published randomised clinical trials indicate that prolonged electrocardiom (ECG) monitoring might enhance the detection of paroxysmal atrial fibrillation (AF) in cryptogenic stroke or transient ischaemic attack (TIA) patients. A device that might be suitable for prolonged ECG monitoring is a smartphone-compatible ECG device (Kardia Mobile, Alivecor, San Francisco, CA, USA) that allows the patient to record a single-lead ECG without the presence of trained health care staff...
August 29, 2017: Trials
https://www.readbyqxmd.com/read/28846802/deceleration-capacity-of-heart-rate-predicts-1-year-mortality-of-patients-undergoing-transcatheter-aortic-valve-implantation
#10
Martin Duckheim, Charlotte Bensch, Linn Kittlitz, Nin Götz, Katharina Klee, Patrick Groga-Bada, Lars Mizera, Meinrad Gawaz, Christine Zuern, Christian Eick
BACKGROUND: Risk prediction in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) is challenging. Development of novel markers for patient risk assessment is of great clinical value. Deceleration capacity (DC) of heart rate is a strong risk predictor in post-infarction patients. HYPOTHESIS: DC provides prognostic information in patients undergoing TAVI. METHODS: We enrolled 374 consecutive patients with severe AS undergoing TAVI...
August 28, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28845401/the-role-of-nt-probnp-in-the-diagnosis-of-ventricular-arrhythmias-in-patients-with-systemic-sclerosis
#11
Lucian Muresan, Ana Petcu, Crina Muresan, Mirela Rinzis, Gabriel Gusetu, Dana Pop, Dumitru Zdrenghea, Simona Rednic
BACKGROUND: In patients with systemic sclerosis, NT-proBNP is a useful diagnostic marker for pulmonary hypertension and ventricular dysfunction, with important prognostic significance. The aim of this study was to assess the relationship between the NT-proBNP levels and the presence and severity of ventricular arrhythmias in patients with scleroderma. METHODS: Forty consecutive patients with a diagnostic of systemic sclerosis according to the EULAR criteria admitted at the Rheumatology Clinic of Cluj-Napoca, Romania, from Jan 2014 to Apr 2014 were enrolled...
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28840364/perservative-paroxysmal-atrioventricular-block-cardiac-syncope-misdiagnosed-as-anxiety-for-more-than-20%C3%A2-years
#12
Sona Tribunyan, Carsten W Israel, Mihran Martirosyan
A 42-year-old woman was referred for cardiac diagnostic work-up of loss of recurrent consciousness over the past 25 years. She received medication with an anxiolytic, an antidepressant, and a neuroleptic drug. After a normal resting ECG, there were 112 episodes of paroxysmal atrioventricular block III° in her 24 h Holter recording with asystole for up to 27 s. The patient was symptomatic only once with dizziness due to an asystole of 8.8 s while she was awake in the early morning. After DDDR pacemaker implantation, the patient was asymptomatic during the following 2 years...
August 24, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/28839099/an-unusual-cause-of-tachyarrhythmia-in-an-otherwise-healthy-young-man
#13
Wessam A Raouf, Khaled Shams, Amr Mansour
A 32-year-old man referred to the cardiology clinic for palpitations was found to have paroxysmal supraventricular tachycardia (SVT) on 24-hour Holter monitoring. His general and cardiac examinations were unremarkable. A transthoracic echocardiographic study to exclude structural heart disease was performed and showed an abnormal structure in relation to the right ventricular (RV) free wall; however, poor echocardiographic windows precluded proper characterisation. Cardiac MR (CMR) was therefore performed...
September 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28837624/rare-variants-in-genes-encoding-the-cardiac-sodium-channel-and-associated-compounds-and-their-impact-on-outcome-of-catheter-ablation-of-atrial-fibrillation
#14
Daniela Husser, Laura Ueberham, Gerhard Hindricks, Petra Büttner, Christie Ingram, Peter Weeke, M Benjamin Shoemaker, Volker Adams, Arash Arya, Philipp Sommer, Dawood Darbar, Dan M Roden, Andreas Bollmann
AIM: Rare variants of genes encoding the cardiac sodium channel and associated compounds have been linked with atrial fibrillation (AF). Nevertheless, current expert consensus does not support genetic testing in AF, which is in part based on the fact that "there is no therapeutic impact derived from AF genetic test results". However, there are no studies available supporting this recommendation. Consequently, this study analyzed the impact of rare variants affecting the cardiac sodium channel on rhythm outcome of AF catheter ablation...
2017: PloS One
https://www.readbyqxmd.com/read/28820736/long-qt-syndrome-diagnosed-in-two-sisters-with-propionic-acidemia-a-case-report
#15
Ensar Duras, Ahmet İrdem, Ozan Özkaya
Propionic acidemia (PA) is a rare autosomal recessive metabolic disorder caused by deficiency of the mitochondrial enzyme propionyl-CoA carboxylase (PCC). This disorder mostly progresses with episodes of metabolic acidosis. Cardiomyopathy is among the cardiac complications known to occur during metabolic decompensation episodes. However, several recent papers emphasized the association of PA and long QT syndrome (LQTS) which may lead to extremely serious and fatal consequences. In this report, we describe two sisters with PA who have prolonged QT duration that were incidentally detected in an outpatient setting...
August 18, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28807079/syncope-during-competitive-events-interrogating-heart-rate-monitor-watches-may-be-useful
#16
Oscar Thabouillot, Kevin Bostanci, Francois Bouvier, Nicolae Dumitrescu, Maria Stéfuriac, Philippe Paule, Nicolas-Charles Roche
This is a case report of a 45-year-old man who reported complete amnesia during the very first kilometer of a 10-km run. He was wearing a heart rate monitor (HRM). The interrogation of his HRM watch showed 200 bpm tachycardia beginning in the first kilometer and increasing up to 220 bpm during the last kilometer. The patient was asked to wear a Holter-monitor (Holter Research Laboratory; Helena, Montana USA) electrocardiogram (ECG) while practicing a training session. This examination allowed for the diagnosis of an adrenergic paroxysmal atrial fibrillation (AF) with an impressive auriculo-ventricular conduction over 260 bpm...
August 15, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28795655/the-use-of-heart-rate-turbulence-and-heart-rate-variability-in-the-assessment-of-autonomic-regulation-and-circadian-rhythm-in-patients-with-systemic-lupus-erythematosus-without-apparent-heart-disease
#17
A R Poliwczak, E Waszczykowska, B Dziankowska-Bartkowiak, M Koziróg, K Dworniak
Background Systemic lupus erythematosus is a progressive autoimmune disease. There are reports suggesting that patients even without overt signs of cardiovascular complications have impaired autonomic function. The aim of this study was to assess autonomic function using heart rate turbulence and heart rate variability parameters indicated in 24-hour ECG Holter monitoring. Methods Twenty-six women with systemic lupus erythematosus and 30 healthy women were included. Twenty-four hour ambulatory ECG-Holter was performed in home conditions...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28791852/cardiac-tumors-in-children-a-20-year-review-of-clinical-presentation-diagnostics-and-treatment
#18
Joanna Kwiatkowska, Anna Wałdoch, Jarosław Meyer-Szary, Piotr Potaż, Marek Grzybiak
BACKGROUND: The use of new imaging techniques has contributed significantly to earlier diagnosis and treatment of cardiac tumors. OBJECTIVES: The aim of the study was to analyze data from children with cardiac tumors in terms of clinical presentation, the role of noninvasive diagnostic procedures and the long-term outcome. MATERIAL AND METHODS: The data analyzed retrospectively concerned 30 children in whom cardiac tumors were diagnosed from January 1995 to July 2015...
March 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28782130/left-atrial-phasic-function-and-heart-rate-variability-in-patients-with-systemic-sclerosis-a-new-part-of-the-old-puzzle
#19
Marijana Tadic, Maja Zlatanovic, Cesare Cuspidi, Ana Stevanovic, Vesna Kocijancic, Sinisa U Pavlovic, Nemanja Damjanov, Vera Celic
OBJECTIVE: We aimed to research left atrial (LA) phasic function and heart rate variability (HRV), as well as their relationship, in subjects with uncomplicated systemic sclerosis (SSc). METHODS: The investigation involved 44 SSc patients and 33 age-matched healthy controls. All participants underwent clinical examination, serological tests, 24-hours Holter monitoring, and echocardiographic examination including strain analysis. RESULTS: Maximum, minimum, and pre-A LA volumes and volume indices were higher in the SSc patients than in the controls...
August 7, 2017: Echocardiography
https://www.readbyqxmd.com/read/28780562/rationale-and-design-of-a-multicentre-prospective-randomised-controlled-clinical-trial-to-evaluate-the-efficacy-of-the-adipose-graft-transposition-procedure-in-patients-with-a-myocardial-scar-the-agtp-ii-trial
#20
Paloma Gastelurrutia, Carolina Gálvez-Montón, Maria Luisa Cámara, Juan Bustamante-Munguira, Pablo García-Pavia, Pablo Avanzas, J Alberto San Román, Domingo Pascual-Figal, Eduardo de Teresa, Maria G Crespo-Leiro, Nicolás Manito, Julio Núñez, Francisco Fernández-Avilés, Ángel Caballero, Albert Teis, Josep Lupón, Ramón Brugada, Carlos Martín, Jacobo Silva, Ana Revilla-Orodea, Sergio J Cánovas, Jose M Melero, Jose J Cuenca-Castillo, Angel Gonzalez-Pinto, Antoni Bayes-Genis
INTRODUCTION: Cardiac adipose tissue is a source of progenitor cells with regenerative capacity. Studies in rodents demonstrated that the intramyocardial delivery of cells derived from this tissue improves cardiac function after myocardial infarction (MI). We developed a new reparative approach for damaged myocardium that integrates the regenerative properties of cardiac adipose tissue with tissue engineering. In the adipose graft transposition procedure (AGTP), we dissect a vascularised flap of autologous pericardial adipose tissue and position it over the myocardial scarred area...
August 4, 2017: BMJ Open
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