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Medical mycology

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https://www.readbyqxmd.com/read/27910139/characterization-of-patients-with-chronic-pulmonary-aspergillosis-according-to-the-new-escmid-ers-ecmm-and-idsa-guidelines
#1
Helmut J F Salzer, Jan Heyckendorf, Barbara Kalsdorf, Thierry Rolling, Christoph Lange
Recently, the Infectious Diseases Society of America (IDSA) and the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) in cooperation with the European Respiratory Society (ERS) and the European Confederation of Medical Mycology (ECMM) published guidelines for the diagnosis of chronic pulmonary aspergillosis (CPA). Both guidelines, however, carry significant differences. We retrospectively applied the diagnostic recommendations on a patient cohort of 71 previously diagnosed CPA patients in order to compare both guidelines...
December 1, 2016: Mycoses
https://www.readbyqxmd.com/read/27858846/the-efficacy-of-fractional-carbon-dioxide-co2-laser-combined-with-luliconazole-1-cream-for-the-treatment-of-onychomycosis-a-randomized-controlled-trial
#2
Bing Rong Zhou, Yan Lu, Felicia Permatasari, He Huang, Jin Li, Juan Liu, Jia An Zhang, Dan Luo, Yang Xu
BACKGROUND: To evaluate the efficacy of fractional carbon dioxide (CO2) laser combined with luliconazole 1% cream for the treatment of onychomycosis and to compare it with that of fractional CO2 laser alone. METHODS: This was a randomized, parallel group, 2-arm, positive-controlled, single-center, superiority trial with a 1:2 allocation ratio. Sixty patients with clinical and mycological diagnosis of onychomycosis were enrolled from the Dermatology Department of the First Affiliated Hospital of Nanjing Medical University in Nanjing, China from March 2015 to May 2015...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27856701/40-years-of-medical-mycology-at-jac
#3
REVIEW
Luis Ostrosky-Zeichner
In the past 40 years, medical mycology has gone from a curiosity in the basements of medical schools to a mainstream branch of clinical microbiology and infectious diseases. Long gone are the days of carefully curated collections of organisms identified purely based on morphology and skill, the lack of therapeutic interventions beyond amphotericin B and the occasional strange case in the ward of a diabetic patient with mucormycosis. We highlight advances in medical mycology as reflected in the past 40 years of JAC...
December 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27843740/verification-of-ribosomal-proteins-of-aspergillus-fumigatus-for-use-as-biomarkers-in-maldi-tof-ms-identification
#4
Sayaka Nakamura, Hiroaki Sato, Reiko Tanaka, Takashi Yaguchi
We have previously proposed a rapid identification method for bacterial strains based on the profiles of their ribosomal subunit proteins (RSPs), observed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). This method can perform phylogenetic characterization based on the mass of housekeeping RSP biomarkers, ideally calculated from amino acid sequence information registered in public protein databases. With the aim of extending its field of application to medical mycology, this study investigates the actual state of information of RSPs of eukaryotic fungi registered in public protein databases through the characterization of ribosomal protein fractions extracted from genome-sequenced Aspergillus fumigatus strains Af293 and A1163 as a model...
2016: Mass Spectrometry
https://www.readbyqxmd.com/read/27815496/lasers-for-onychomycosis-current-status
#5
REVIEW
Aditya K Gupta, Kelly A Foley, Sarah G Versteeg
Many studies that have been recently published investigate the efficacy of laser treatment for onychomycosis. These studies support the current US Food and Drug Administration (FDA) approval of lasers for the 'temporary increase in clear nail'. Clear nail growth is an important treatment goal for patients; however, many do not realise that laser treatment is not a cure for onychomycosis. The current article briefly reviews why lasers may be theoretically effective in treating onychomycosis and critically reviews published laser studies for onychomycosis in light of the standards employed in drug trials...
November 4, 2016: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27800138/growing-incidence-of-non-dermatophyte-onychomycosis-in-tehran-iran
#6
Marjan Motamedi, Zeinab Ghasemi, Mohammad Reza Shidfar, Leila Hosseinpour, Hossein Khodadadi, Kamiar Zomorodian, Hossein Mirhendi
BACKGROUND: Non-dermatophyte onychomycosis (NDO) is caused by a wide range of mold fungi other than dermatophytes, and has been reported at various rates in different countries worldwide. Studies on the incidence of NDO in the community are essential for understanding its epidemiology and control, as well as for the appropriate treatment of these infections. OBJECTIVES: In this study, the incidence of NDO in Tehran, Iran, was compared to the incidence of onychomycoses due to dermatophytes and yeasts...
August 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27790797/causative-agents-of-onychomycosis-a-7-year-study
#7
Mostafa Chadeganipour, Rasoul Mohammadi
BACKGROUND: Onychomycosis is principally caused by dermatophyte species, but nondermatophyte molds and yeasts have also been involved, causing different clinical manifestations. The aim of this investigation is to determine the clinicomycological and epidemiological profile of the etiologic agents of onychomycosis. METHODS: The study population included 9,785 suspected cases of onychomycosis referred to the Medical Mycology Reference Laboratory in Isfahan, Iran, during 2007-2014...
November 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27790435/mycological-profile-of-sputum-of-hiv-positive-patients-with-lower-respiratory-tract-infection-and-its-correlation-with-cd4-t-lymphocyte-count
#8
Jyotsna Chandwani, Nitya Vyas, Saroj Hooja, Babita Sharma, Rakesh Maheshwari
INTRODUCTION: Fungal respiratory infections are important cause of mortality and morbidity among HIV positive individuals. They account for up to 70% of illness in Acquired Immunodeficiency Disease Syndrome cases (AIDS). The range of illness varies from asymptomatic mucosal candidiasis to overwhelming disseminated infections. In these patients dissemination of fungus leads to very serious outcomes hence, it is important to have the knowledge of prevailing profile of fungus causing infections, so that it can be treated at the onset...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27730797/pioneers-in-medical-mycology-and-mycobacteriology
#9
Preeti Pillai, Mahesh Lakhe, Anjali Shetty, Rajeev Soman
No abstract text is available yet for this article.
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27703021/aspergillus-antibody-detection-diagnostic-strategy-and-technical-considerations-from-the-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-de-mycologie-m%C3%A3-dicale-french-society-for-medical-mycology-expert-committee
#10
F Persat, C Hennequin, J P Gangneux
Until now, there has been no consensus on the best method for the detection of anti-Aspergillus antibodies, a key diagnostic tool for chronic aspergilloses. To better appreciate the usage of and confidence in these techniques, the Société Française de Mycologie Médicale (French Society for Medical Mycology; SFMM) performed a two-step survey of French experts. First, we administered an initial survey to French labs performing Aspergillus serology to depict usage of the different techniques available for Aspergillus serology...
October 4, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27648562/introducing-mushroom-fruiting-patterns-from-the-swiss-national-poisons-information-centre
#11
Katharina M Schenk-Jäger, Simon Egli, David Hanimann, Beatrice Senn-Irlet, Hugo Kupferschmidt, Ulf Büntgen
Changes in the ecology of macrofungi are poorly understood, not only because much of their life cycle is hidden belowground, but also because experiments often miss real-world complexity and most fruitbody inventories are limited in space and time. The National Poisons Information Centre 'Tox Info Suisse' provides countrywide 24hours/7days medical advice in case of poisonings since 1966. Here, we introduce a total of 12,126 mushroom-related phone calls that were received by Tox Info Suisse between 1966 and 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27581779/mycological-education-for-dermatologists
#12
Katsutaro Nishimoto
Mycotic infections remain important in dermatological clinics. Therefore the mycological training curriculum needs to be reorganized starting from the beginning of dermatological education, including routine examination procedures, such as potassium hydroxide examination, culture of pathogenic fungi, histopathology, treatment guidelines, and the recent advances in medical mycology.Several mycological institutes will be selected and announced in the journal to provide support for mycological examinations and to publish important cases treated in clinics...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581775/studies-in-phylogeny-development-of-rapid-identificationmethods-antifungal-susceptibility-and-growth-rates-of-clinical-strains-of-sporothrix-schenckii-complex-in-japan
#13
Rumi Suzuki, Alimu Yikelamu, Reiko Tanaka, Ken Igawa, Hiroo Yokozeki, Takashi Yaguchi
Sporotrichosis is a fungal infection caused by the Sporothrix species, which have distinct virulence profiles and geographic distributions. We performed a phylogenetic study in strains morphologically identified as Sporothrix schenckii from clinical specimens in Japan, which were preserved at the Medical Mycology Research Center, Chiba University. In addition, we examined the in vitro antifungal susceptibility and growth rate to evaluate their physiological features. Three hundred strains were examined using sequence analysis of the partial calmodulin gene, or polymerase chain reaction(PCR)method using newly designed species-specific primers; 291 strains were Sporothrix globosa and 9 strains were S...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27579738/nail-abnormalities-in-patients-with-vitiligo
#14
Ilteris Oguz Topal, Sule Gungor, Ozgur Emek Kocaturk, Hatice Duman, Mustafa Durmuscan
BACKGROUND: Vitiligo is an acquired pigmentary skin disorder affecting 0.1-4% of the general population. The nails may be affected in patients with an autoimmune disease such as psoriasis, and in those with alopecia areata. It has been suggested that nail abnormalities should be apparent in vitiligo patients. OBJECTIVE: We sought to document the frequency and clinical presentation of nail abnormalities in vitiligo patients compared to healthy volunteers. We also examined the correlations between nail abnormalities and various clinical parameters...
July 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27516998/immunoreactivity-analysis-of-toxoplasma-gondii-recombinant-antigen-rsag3-in-sera-from-immunized-balb-c-mice-and-toxoplasmosis-patients
#15
Mohammad Hossein Motazedian, Bahram Kazemi, Bahador Shahriari, Mojgan Bandehpour, Khadijeh Khanaliha
BACKGROUND: The coccidian protozoa Toxoplasma gondii is an obligate intracellular parasite of humans and other warm-blooded animals. Diagnosis of toxoplasmosis is of considerable medical importance for human, especially pregnant women and immunocompromised individuals. The apply of an Escherichia coli recombinant antigen(s) would be significantly useful in developing standardization of the diagnostic tests and reducing their costs. In this study, immunoreactivity of recombinant SAG3 against sera from immunized mice and human anti-T...
July 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27477178/trichotillomania-bizzare-patern-of-hair-loss-at-11-year-old-girl
#16
Jana Zímová, Pavlína Zímová
Trichotillomania (TTM) is defined by the Diagnostics and Statistic Manual of Mental Disorders, 4th edition (DMS-IV) as hair loss from a patient`s repetitive self-pulling of hair. The disorder is included under anxiety disorders because it shares some obsessive-compulsive features. Patients have the tendency towards feelings of unattractiveness, body dissatisfaction, and low self-esteem (1,2). It is a major psychiatric problem, but many patients with this disorder first present to a dermatologist. An 11-year-old girl came to our department with a 2-month history of diffuse hair loss on the frontoparietal and parietotemporal area (Figure 1)...
June 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27450641/-clinical-problems-in-medical-mycology-problem-number-50
#17
Laura Guadalupe Walker, Alicia Arechavala, Fernando Messina, Ricardo Negroni, Gabriela Santiso
We present the case of a 34 year-old man, HIV-positive, who had suffered a disseminated histoplasmosis treated with amphotericin B one year before his admission. He was admitted at the Infectious Diseases Muñiz Hospital with a non-lithiasic chlolecystitis. During the clinical examination perigenital skin lesions compatible with tinea cruris, as well as proximal subungual onychomycoses of toenails, were observed. Microsporum gypseum was isolated from both types of lesions. Oral terbinafine led to a good clinical response...
July 19, 2016: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/27450640/-clinical-problems-in-medical-mycology-problem-number-49
#18
Fernando Messina, Alicia Arechavala, Gabriela Santiso, Ricardo Negroni, Marcela Ortiz de Zárate, Laura Walker, Roxana Depardo
The case of a 22 year-old pregnant woman, suffering an infectious disease with skin lesions on the head, is presented. The patient referred a systemic mycosis 5 years before, treated with oral antifungal, with good clinical response. The mycological study of the skin clinical samples showed multiple budding yeast like elements consistent with Paracoccidioides, and the same organism was isolated in cultures. Physical examination and images studies did not show other location of the mycosis. The patient was treated with oral cotrimoxazole during pregnancy and lactation; afterwards this treatment was stopped and replaced by itraconazole by oral route at a daily dose of 200mg due to the poor clinical response observed with the first treatment...
July 19, 2016: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/27428339/-frequency-of-invasive-fungal-infections-in-a-mexican-high-specialty-hospital-experience-of-21-years
#19
Luis Javier Méndez-Tovar, Jessica Aline Mejía-Mercado, Patricia Manzano-Gayosso, Francisca Hernández-Hernández, Rubén López-Martínez, Israel Silva-González
BACKGROUND: Factors such as cancer, HIV infection, use of corticosteroids and antibiotics, favors the increase in the number of invasive fungal infections (IFI) worldwide. METHODS: To determine the frequency and epidemiological aspects of IFI at a mexican, a review of the proven cases diagnosed over the past 21 years (1993-2013) in the Laboratory of Medical Mycology was performed. RESULTS: A total of 472 cases were identified as: 261 candidiasis, 82 mucormycosis, 60 cryptococcosis, 43 aspergillosis and 16 histoplasmosis...
September 2016: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/27382801/-superficial-mycoses-casuistry-of-the-mycology-department-of-the-instituto-nacional-de-higiene-rafael-rangel-caracas-venezuela-2001-2014
#20
Ana María Capote, Giuseppe Ferrara, María Mercedes Panizo, Nataly García, Víctor Alarcón, Vera Reviakina, Maribel Dolande
The superficial mycoses are very common infectious diseases and therefore are a frequent reason for medical consultation. The aim of this study was to determine the diagnostic frequency of superficial mycoses in the Mycology Department of the Instituto Nacional de Higiene "Rafael Rangel" during 14 years (2001-2014). A retrospective cross-sectional study was performed to review the mycological records of patients with presumptive diagnosis of superficial mycosis. Nails, hairs and epidermal scales were the processed samples...
March 2016: Investigación Clínica
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