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https://www.readbyqxmd.com/read/28438524/trajectories-of-mental-health-related-service-use-among-adolescents-with-histories-of-early-externalizing-problems
#1
Yuko Okado, Emily Ewing, Christina Rowley, Damon E Jones
PURPOSE: To inform efforts to reduce costly service utilization, the present study examined longitudinal trajectories of mental health-related outpatient and residential service use among at-risk youth with a history of early externalizing problems. METHODS: A cohort of 809 children in the Fast Track Project, a multisite longitudinal study of children at risk for conduct disorder, were followed prospectively from kindergarten through 12th grade. They resided in high-risk areas with high rates of poverty, crime, and violence...
April 21, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28437313/enhanced-recovery-after-surgery-for-noncolorectal-surgery-a-systematic-review-and-meta-analysis-of-major-abdominal-surgery
#2
Anthony Visioni, Rupen Shah, Emmanuel Gabriel, Kristopher Attwood, Moshim Kukar, Steven Nurkin
OBJECTIVE: To evaluate the impact of enhanced recovery after surgery (ERAS) protocols across noncolorectal abdominal surgical procedures. BACKGROUND: ERAS programs have been studied extensively in colorectal surgery and adopted at many centers. Several studies testing such protocols have shown promising results in improving postoperative outcomes across various surgical procedures. However, surgeons performing major abdominal procedures have been slower to adopt these ERAS protocols...
April 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28435128/randomized-trial-on-fast-track-care-in-colorectal-surgery-for-deep-infiltrating-endometriosis
#3
Marco Scioscia, Marcello Ceccaroni, Irene Gentile, Roberto Rossini, Roberto Clarizia, Davide Brunelli, Giacomo Ruffo
STUDY OBJECT: To study the application of a fast-track care protocol in colorectal surgery for deep infiltrating endometriosis. Bowel endometriosis is an infrequent but not rare condition that often needs intestinal surgery and imposes a high economic burden on society. DESIGN: Prospective randomized trial (Canadian Task Force I). SETTING: Tertiary referral center. PATIENTS: We randomly assigned 227 patients with preoperative evidence of bowel endometriosis to a fast-track (no preoperative bowel preparation, early restoration of diet, no postoperative antibiotics, and early post-operative mobilization) or conventional care for laparoscopic intestinal surgery...
April 18, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28431106/ultrasound-cut-off-values-for-intima-media-thickness-of-temporal-facial-and-axillary-arteries-in-giant-cell-arteritis
#4
Valentin S Schäfer, Aaron Juche, Sofia Ramiro, Andreas Krause, Wolfgang A Schmidt
Objective.: To evaluate the intima-media thickness (IMT) of arteries involved in GCA for determining cut-off values. Methods.: Forty newly diagnosed GCA patients in a fast-track GCA clinic and 40 age- and sex-matched controls were included. IMT measurement was performed at or within 24 h after diagnosis. The common superficial temporal arteries with their frontal and parietal branches and the facial arteries were bilaterally examined with a 10-22 MHz probe and the axillary artery with a 6-18 MHz probe...
April 20, 2017: Rheumatology
https://www.readbyqxmd.com/read/28424847/characterization-of-microtubule-buckling-in-living-cells
#5
Carla Pallavicini, Alejandro Monastra, Nicolás González Bardeci, Diana Wetzler, Valeria Levi, Luciana Bruno
Microtubules are filamentous biopolymers involved in essential biological processes. They form key structures in eukaryotic cells, and thus it is very important to determine the mechanisms involved in the formation and maintenance of the microtubule network. Microtubule bucklings are transient and localized events commonly observed in living cells and characterized by a fast bending and its posterior relaxation. Active forces provided by molecular motors have been indicated as responsible for most of these rapid deformations...
April 19, 2017: European Biophysics Journal: EBJ
https://www.readbyqxmd.com/read/28423779/fast-and-efficient-feature-engineering-for-multi-cohort-analysis-of-ehr-data
#6
Michal Ozery-Flato, Chen Yanover, Assaf Gottlieb, Omer Weissbrod, Naama Parush Shear-Yashuv, Yaara Goldschmidt
We present a framework for feature engineering, tailored for longitudinal structured data, such as electronic health records (EHRs). To fast-track feature engineering and extraction, the framework combines general-use plug-in extractors, a multi-cohort management mechanism, and modular memoization. Using this framework, we rapidly extracted thousands of features from diverse and large healthcare data sources in multiple projects.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28423529/pif-promotes-brain-re-myelination-locally-while-regulating-systemic-inflammation-clinically-relevant-multiple-sclerosis-m-smegmatis-model
#7
Giuseppe Migliara, Martin Mueller, Alessia Piermattei, Chaya Brodie, Michael J Paidas, Eytan R Barnea, Francesco Ria
Neurologic disease diagnosis and treatment is challenging. Multiple Sclerosis (MS) is a demyelinating autoimmune disease with few clinical forms and uncertain etiology. Current studies suggest that it is likely caused by infection(s) triggering a systemic immune response resulting in antigen/non-antigen-related autoimmune response in central nervous system (CNS). New therapeutic approaches are needed. Secreted by viable embryos, PreImplantation Factor (PIF) possesses a local and systemic immunity regulatory role...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422660/weak-classifier-for-density-estimation-in-eye-localization-and-tracking
#8
Gabriel M Araujo, Felipe M L Ribeiro, Waldir S Junior, Eduardo A B da Silva, Siome K Goldenstein
In this work, we propose a fast weak classifier that can detect and track eyes in video sequences. The approach relies on a least-squares detector based on the Inner Product Detector (IPD) that can estimate a probability density distribution for a feature's location - which fits naturally with a Bayesian estimation cycle, such as a Kalman or particle filter. As a leastsquares sliding window detector, it possesses tolerance to small variations in the desired pattern while maintaining good generalization capabilities and computational efficiency...
April 13, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28421940/not-a-level-playing-field
#9
(no author information available yet)
Your news story on the 'Nurse First' fast-track course is interesting (news online, 31 March). Superficially, the two-year programme appears to be a good way of recruiting talented and appropriately qualified graduates into a nursing career.
April 19, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28420989/fda-facilitated-regulatory-pathways-visualizing-their-characteristics-development-and-authorization-timelines
#10
Lawrence Liberti, Magda Bujar, Alasdair Breckenridge, Jarno Hoekman, Neil McAuslane, Pieter Stolk, Hubert Leufkens
The US Food and Drug Administration (FDA) has four facilitated regulatory pathways (FRPs): Fast Track (FT), Breakthrough Therapy (BTD), Priority Review (PR), and Accelerated Approval (AA). Only PR specifies an expedited review timeline (6 months). We sought to determine to what extent the combination of two or more FRPs influenced development and approval times. We developed a "metro map" to illustrate FRP elements and their influence on review times. We assessed 125 new active substances (approved January 2013 to December 2015) 74 of which used one or more FRPs...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28420134/visual-detection-and-tracking-system-for-a-spherical-amphibious-robot
#11
Shuxiang Guo, Shaowu Pan, Liwei Shi, Ping Guo, Yanlin He, Kun Tang
With the goal of supporting close-range observation tasks of a spherical amphibious robot, such as ecological observations and intelligent surveillance, a moving target detection and tracking system was designed and implemented in this study. Given the restrictions presented by the amphibious environment and the small-sized spherical amphibious robot, an industrial camera and vision algorithms using adaptive appearance models were adopted to construct the proposed system. To handle the problem of light scattering and absorption in the underwater environment, the multi-scale retinex with color restoration algorithm was used for image enhancement...
April 15, 2017: Sensors
https://www.readbyqxmd.com/read/28418710/lung-cancer-guidelines-in-sweden-denmark-norway-and-finland-a-comparison
#12
Niels Lyhne Christensen, Antti Jekunen, Sebastian Heinonen, Susanne Oksbjerg Dalton, Torben Riis Rasmussen
BACKGROUND: The Nordic countries are similar in terms of demographics and health care organization. Yet there are marked differences in lung cancer mortality, for which Denmark historically has had the poorest outcome. One of several possible reasons for these differences could have to do with how lung cancer is diagnosed and treated in the different Nordic countries. However, among the four most populous Nordic countries: Sweden, Denmark, Norway and Finland, there is a paucity of knowledge about differences and similarities in recommendations in the national guidelines for non-small cell lung cancer (NSCLC) and the methodology by which the guidelines are developed...
April 18, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28417834/adaptive-changes-in-the-perception-of-fast-and-slow-movement-at-different-head-positions
#13
Roberto Panichi, Chiara Occhigrossi, Aldo Ferraresi, Mario Faralli, Marco Lucertini, Vito E Pettorossi
BACKGROUND: This paper examines the subjective sense of orientation during asymmetric body rotations in normal subjects. METHODS: Self-motion perception was investigated in 10 healthy individuals during asymmetric whole-body rotation with different head orientations. Both on-vertical axis and off-vertical axis rotations were employed. Subjects tracked a remembered earth-fixed visual target while rotating in the dark for four cycles of asymmetric rotation (two half-sinusoidal cycles of the same amplitude, but of different duration)...
May 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28414681/what-can-erode-through-lungs-bone-and-skin
#14
J M Manalac, D Shankaranayanan, J Paul-Olivier, L Guidry, N R Sells
CASE: A 51 year old African American Man without significant past history presented with three weeks of persistent cough productive of copious yellow sputum. He denied fevers, chills, hemoptysis, dyspnea, weight or appetite changes, sick contacts, recent travel. On physical examination, the patient was afebrile and appeared comfortable. He had decreased air entry of the left lower lobe with dullness to percussion. A 5x3 cm fluctuant mass was incidentally found on the left anterior chest wall at the level of the 11th rib with yellow expressible exudate at which time the patient reported a minor trauma sustained 3 weeks prior...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28413808/vessel-tree-tracking-in-angiographic-sequences
#15
Dong Zhang, Shanhui Sun, Ziyan Wu, Bor-Jeng Chen, Terrence Chen
We present a method to track vessels in angiography [contrast filled vessels in two-dimensional (2-D) x-ray fluoroscopy]. Finding correspondence of a vessel tree from consecutive angiogram frames provides significant value in computer-aided clinical applications such as fast vessel tree segmentation, three-dimensional (3-D) vessel topology reconstruction from corresponding centerlines, cardiac motion understanding, etc. However, establishing an accurate vessel tree correspondence (vessel tree tracking) is a nontrivial problem due to nonlinear periodic cardiac and breathing motion in 2-D views, foreshortening, false bifurcations due to 3-D to 2-D projection, occlusion from other anatomies, etc...
April 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28413420/overcrowding-in-emergency-departments-a-review-of-strategies-to-decrease-future-challenges
#16
REVIEW
Mohammad H Yarmohammadian, Fatemeh Rezaei, Abbas Haghshenas, Nahid Tavakoli
Emergency departments (EDs) are the most challenging ward with respect to patient delay. The goal of this study is to present strategies that have proven to reduce delay and overcrowding in EDs. In this review article, initial electronic database search resulted in a total of 1006 articles. Thirty articles were included after reviewing full texts. Inclusion criteria were assessments of real patient flows and implementing strategies inside the hospitals. In this study, we discussed strategies of team triage, point-of-care testing, ideal ED patient journey models, streaming, and fast track...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28411116/global-field-synchronization-in-gamma-range-of-the-sleep-eeg-tracks-sleep-depth-artifact-introduced-by-a-rectangular-analysis-window
#17
Thomas Rusterholz, Peter Achermann, Roland Dürr, Thomas Koenig, Leila Tarokh
BACKGROUND: Investigating functional connectivity between brain networks has become an area of interest in neuroscience. Several methods for investigating connectivity have recently been developed, however, these techniques need to be applied with care. We demonstrate that global field synchronization (GFS), a global measure of phase alignment in the EEG as a function of frequency, must be applied considering signal processing principles in order to yield valid results. NEW METHOD: Multichannel EEG (27 derivations) was analyzed for GFS based on the complex spectrum derived by the fast Fourier transform (FFT)...
April 11, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28409282/motor-neuron-vulnerability-and-resistance-in-amyotrophic-lateral-sclerosis
#18
REVIEW
Jik Nijssen, Laura H Comley, Eva Hedlund
In the fatal disease-amyotrophic lateral sclerosis (ALS)-upper (corticospinal) motor neurons (MNs) and lower somatic MNs, which innervate voluntary muscles, degenerate. Importantly, certain lower MN subgroups are relatively resistant to degeneration, even though pathogenic proteins are typically ubiquitously expressed. Ocular MNs (OMNs), including the oculomotor, trochlear and abducens nuclei (CNIII, IV and VI), which regulate eye movement, persist throughout the disease. Consequently, eye-tracking devices are used to enable paralysed ALS patients (who can no longer speak) to communicate...
April 13, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28407106/rapid-decline-in-hiv-incidence-among-persons-who-inject-drugs-during-a-fast-track-combination-prevention-program-after-an-hiv-outbreak-in-athens
#19
Vana Sypsa, Mina Psichogiou, Dimitrios Paraskevis, Georgios Nikolopoulos, Chrissa Tsiara, Dimitra Paraskeva, Katerina Micha, Meni Malliori, Anastasia Pharris, Lucas Wiessing, Martin Donoghoe, Samuel Friedman, Don Des Jarlais, Georgios Daikos, Angelos Hatzakis
Background.: A "seek-test-treat" intervention (ARISTOTLE) was implemented in response to an outbreak of human immunodeficiency virus (HIV) infection among persons who inject drugs (PWID) in Athens. We assess trends in HIV incidence, prevalence, risk behaviors and access to prevention/treatment. Methods.: Methods included behavioral data collection, provision of injection equipment, HIV testing, linkage to opioid substitution treatment (OST) programs and HIV care during 5 rounds of respondent-driven sampling (2012-2013)...
April 12, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28405277/a-hidden-markov-movement-model-for-rapidly-identifying-behavioral-states-from-animal-tracks
#20
Kim Whoriskey, Marie Auger-Méthé, Christoffer M Albertsen, Frederick G Whoriskey, Thomas R Binder, Charles C Krueger, Joanna Mills Flemming
Electronic telemetry is frequently used to document animal movement through time. Methods that can identify underlying behaviors driving specific movement patterns can help us understand how and why animals use available space, thereby aiding conservation and management efforts. For aquatic animal tracking data with significant measurement error, a Bayesian state-space model called the first-Difference Correlated Random Walk with Switching (DCRWS) has often been used for this purpose. However, for aquatic animals, highly accurate tracking data are now becoming more common...
April 2017: Ecology and Evolution
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