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Compounding pharmacy

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https://www.readbyqxmd.com/read/27911513/regulating-compounding-pharmacies
#1
Ashley Noble
No abstract text is available yet for this article.
November 2016: NCSL Legisbrief
https://www.readbyqxmd.com/read/27894973/is-there-nothing-new-under-the-sun-the-influence-of-herbals-and-pharmacopoeias-on-ethnobotanical-traditions-in-albacete-spain
#2
Diego Rivera, Alonso Verde, Concepción Obón, Francisco Alcaraz, Candelaria Moreno, Teresa Egea, José Fajardo, José Antonio Palazón, Arturo Valdés, Maria Adele Signorini, Piero Bruschi
ETHNOPHARMACOLOGICAL RELEVANCE: This paper has two overarching aims: (1) presenting the results of studying the Albacete tariff of medicines of 1526 and (2) broadly analyzing the origin and influences of medicinal traditional knowledge in the region of Albacete, Spain. We use historical and modern literature that may have influenced this knowledge. Our primary goal was to determine the ingredients used in the pharmacy in the 16th century CE in Albacete through the analysis of the tariff, and our secondary goal was to investigate until when ingredients and uses present in pharmacy and herbals persisted in later periods...
November 25, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27877094/raman-spectroscopy-a-sensitive-and-specific-technique-for-determining-the-accuracy-of-compounded-pharmaceutical-formulations
#3
Claudia Meek, Jihye Hoe, Jason Evans, Rosanne Thurman, Lisa Ashworth, Richard Leff
OBJECTIVES: Raman spectroscopy is a widely used technology to identify chemical unknowns or confirm chemical identity. We have tested Raman spectrometry to identify compounded pharmaceutical formulations. In contrast to the commonly used application mentioned above, compounded pharmaceutical formulations contain a mixture of ingredients, and the Raman spectrometer is being used to correctly identify the composition of the complete pharmaceutical formulation, including the active pharmaceutical ingredient(s)...
September 2016: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/27863984/pharmacy-preparations-back-in-the-limelight-pharmacists-make-up-your-mind
#4
Daan J A Crommelin, Yvonne Bouwman-Boer
In this contribution to the theme issue recognizing prof. Florence's achievements as editor -in-chief of the Int. J. Pharmaceutics, we analyze the future of pharmacy preparations (also known as extemporaneous preparations or compounded products). Pharmacy preparations, long considered as an endangered part of the pharmacy profession on its way to extinction, may be at the brink of a revival. Drivers of this revival are a set of changes related to new clinical concepts and supply shortages. Moreover, new production and IT paradigms are being developed that facilitate the preparation processes and provide the necessary quality management systems...
September 28, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27863653/pharmacy-preparations-back-in-the-limelight-pharmacists-make-up-your-mind
#5
Daan J A Crommelin, Yvonne Bouwman-Boer
In this contribution to the theme issue recognizing prof. Florence's achievements as editor -in-chief of the Int. J. Pharmaceutics, we analyze the future of pharmacy preparations (also known as extemporaneous preparations or compounded products). Pharmacy preparations, long considered as an endangered part of the pharmacy profession on its way to extinction, may be at the brink of a revival. Drivers of this revival are a set of changes related to new clinical concepts and supply shortages. Moreover, new production and IT paradigms are being developed that facilitate the preparation processes and provide the necessary quality management systems...
November 30, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27816105/stevia-glycosides-chemical-and-enzymatic-modifications-of-their-carbohydrate-moieties-to-improve-the-sweet-tasting-quality
#6
Gerrit J Gerwig, Evelien M Te Poele, Lubbert Dijkhuizen, Johannis P Kamerling
Stevia glycosides, extracted from the leaves of the plant Stevia rebaudiana Bertoni, display an amazing high degree of sweetness. As processed plant products, they are considered as excellent bio-alternatives for sucrose and artificial sweeteners. Being noncaloric and having beneficial properties for human health, they are the subject of an increasing number of studies for applications in food and pharmacy. However, one of the main obstacles for the successful commercialization of Stevia sweeteners, especially in food, is their slight bitter aftertaste and astringency...
2016: Advances in Carbohydrate Chemistry and Biochemistry
https://www.readbyqxmd.com/read/27777075/influences-on-the-frequency-and-type-of-community-pharmacy-services
#7
William R Doucette, Julia J Rippe, Caroline A Gaither, David H Kreling, David A Mott, Jon C Schommer
OBJECTIVES: To describe services provided by community pharmacies and to identify factors associated with services being provided in community pharmacies. DESIGN: Cross-sectional national mail survey. SETTING AND PARTICIPANTS: Pharmacists actively practicing in community pharmacies (independent, chain, mass merchandisers, and supermarkets). OUTCOME MEASURES: Frequency and type of pharmacy services available in a community pharmacy, including medication therapy management, immunization, adjusting medication therapy, medication reconciliation, disease state management, health screening or coaching, complex nonsterile compounding, and point-of-care testing...
October 21, 2016: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/27754435/thymol-mitigates-cadmium-stress-by-regulating-glutathione-levels-and-reactive-oxygen-species-homeostasis-in-tobacco-seedlings
#8
Xiefeng Ye, Tianxiao Ling, Yanfeng Xue, Cunfa Xu, Wei Zhou, Liangbin Hu, Jian Chen, Zhiqi Shi
Thymol is a famous plant-derived compound that has been widely used in pharmacy due to its antioxidant and antimicrobial properties. However, the modulation of intrinsic plant physiology by thymol remains unclear. It is a significant challenge to confer plant tolerance to Cd (cadmium) stress. In the present study physiological, histochemical, and biochemical methods were applied to investigate thymol-induced Cd tolerance in tobacco (Nicotiana tabacum) seedlings. Thymol was able to alleviate Cd-induced growth inhibition of tobacco seedlings in both dose- and time-dependent manners...
October 14, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27729683/usp-800-key-considerations-and-changes-for-health-systems
#9
EDITORIAL
Priya Sahadeo, Robert J Weber
On March 28, 2014, The United States Pharmacopeia and The National Formulary (USP-NF) published USP General Chapter <800> Hazardous Drugs-Handling in Healthcare Settings, as open for public comment in the USP Pharmacopeial Forum (PF) 40(3). Pharmacy directors must be proactive in understanding the impact that USP <800> will have on their processes for preparing sterile products. USP General Chapter <797> pertains to the compounding of both hazardous and nonhazardous drugs. USP <800> serves as a new standard to guide the handling of hazardous drugs in order to protect patients, health care personnel, and the environment...
November 2015: Hospital Pharmacy
https://www.readbyqxmd.com/read/27704551/challenge-of-paediatric-compounding-to-solid-dosage-forms-sachets-and-hard-capsules-finnish-perspective
#10
Mia Sivén, Satu Kovanen, Outi Siirola, Tuomas Hepojoki, Sari Isokirmo, Niina Laihanen, Tiina Eränen, Jukka Pellinen, Anne M Juppo
OBJECTIVES: The study evaluated the quality of compounded sachets and hard gelatine capsules and their feasibility in paediatric drug administration. METHODS: Commercial tablets were compounded to sachets and capsules in hospital environment, and the uniformity of content and simulated drug dose were determined. KEY FINDINGS: Compounded formulations were successfully obtained for a range of drug substances; dipyridamole, spironolactone, warfarin and sotalol formulations were within acceptable limits for uniformity of content, in most cases...
October 5, 2016: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/27698505/guidelines-for-the-establishment-of-appropriate-beyond-use-dating-of-sterile-compounded-admixtures
#11
Jamin Engel, Nicole Lazar
To support compounding of products that are sterile and chemically stable, beyond use dating of admixtures must include a thorough evaluation of appropriate resources. In most instances, resources provide documentation of a specific compounded admixture, at a specific concentration and storage parameters, that does not coincide with current operations or patient-specific requirements. To meet the operational demands of a pharmacy, institutions employ a referenced guideline approach to guide decision making for safe sterile admixing...
September 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27688885/the-fate-of-the-new-pharmacy-bill-going-backwards-or-forwards
#12
Kah Seng Lee, Yen Wei Lim, Long Chiau Ming
BACKGROUND: The proposed Pharmacy Bill of Malaysia which served to consolidate and harmonise the existing pharmacy legislation which has been used for more than 60 years. This new Pharmacy Bill contains 17 parts and a total of 170 legislative sections covering laws governing pharmacy practice, medicinal products classification, registration, sale, supply, licensing etc. Our article could serve as a case study on pharmacy jurisprudence and drug regulation as well as the governance for medicines...
2016: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/27658320/development-of-a-novel-physico-chemically-and-microbiologically-stable-oral-solution-of-flecainide-for-pediatrics
#13
Ana Santoveña, Irma Charola, Javier Suárez-González, Nuria Teigell-Pérez, Susana García-van Nood, Mabel Soriano, José B Fariña
There is as yet no commercialized preparation for oral administration of flecainide acetate (FA) to children. In such cases, manipulation of commercial tablets is the usual practice in pharmacy services of hospitals and compounding pharmacies, to provide a suitable dosage form for this vulnerable pediatric population group. In this study we have formulated FA as an oral solution, as an alternative to the suspension elaborated from commercial tablets. Due to this sensitivity of young patients, we have used the pure active pharmaceutical ingredient (API) and the lowest permitted levels of pediatric excipients...
September 23, 2016: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/27605315/fda-starts-showing-its-plans-for-oversight-of-pharmacy-compounding
#14
Cheryl A Thompson
No abstract text is available yet for this article.
September 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27593449/evaluation-of-seasonal-changes-of-triterpenic-acid-contents-in-viscum-album-from-different-host-trees
#15
Magdalena Wójciak-Kosior, Ireneusz Sowa, Kamila Pucek, Grażyna Szymczak, Ryszard Kocjan, Piotr Luchowski
CONTEXT: Viscum album L. (Loranthaceae) is a semi-parasitic plant used in pharmacy and medicine mostly for its hypotensive and anticancer activity. The effects may be related to the presence of triterpenic acids, such as betulinic (BA) and oleanolic (OA) acids. OBJECTIVES: In our investigations the content of triterpenic acids in V. album from different host trees depending on the season of harvest was determined. MATERIAL AND METHODS: V. album herb was dried and extracted with ethyl acetate using ultrasound energy...
September 4, 2016: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27582674/a-cluster-of-presumed-noninfectious-endophthalmitis-after-intravitreal-injection-of-bevacizumab-long-term-follow-up
#16
Federico Ricci, Antonio Calabrese, Cecilia De Felici, Filippo Missiroli, Marco Pileri, Federico Regine
PURPOSE: To report the outcome of 5 consecutive cases of presumed, noninfectious endopththalmitis following intravitreal injection of bevacizumab (IVB). METHODS: Ten pre-loaded syringes of bevacizumab (1.25 mg/50 µL) furnished by a compounding pharmacy were injected intravitreally. Treatments were performed in the operating room by the same surgeon on 2 consecutive days. RESULTS: Of 10 eyes, 5 showed moderate to severe ocular inflammation within a few days of injection...
2016: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/27570987/evaluation-of-the-in-vitro-ocular-toxicity-of-the-fortified-antibiotic-eye-drops-prepared-at-the-hospital-pharmacy-departments
#17
Anxo Fernández-Ferreiro, Miguel González-Barcia, María Gil-Martínez, María Santiago Varela, María Pardo, José Blanco-Méndez, Antonio Piñeiro-Ces, María Jesús Lamas Díaz, Francisco J Otero-Espinar
The use of parenteral antibiotic eye drop formulations with non-marketed compositions or concentrations, commonly called fortified antibiotic eye drops, is a common practice in Ophthalmology in the hospital setting. The aim of this study was to evaluate the in vitro ocular toxicity of the main fortified antibiotic eye drops prepared in the Hospital Pharmacy Departments. We have conducted an in vitro experimental study in order to test the toxicity of gentamicin, amikacin, cefazolin, ceftazidime, vancomycin, colistimethate sodium and imipenem-cilastatin eye drops; their cytotoxicity and acute tissue irritation have been evaluated...
September 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27553051/intracameral-cefuroxime-in-the-prevention-of-postoperative-endophthalmitis-an-experience-from-hong-kong
#18
Alex Lap-Ki Ng, Wilson Wai-Tat Tang, Patrick Siu-Hung Li, Kenneth Kai-Wang Li
PURPOSE: The purpose was to study the effect of introducing intracameral cefuroxime, which was compounded by a hospital pharmacy, on postoperative endophthalmitis in a tertiary eye centre in Hong Kong. METHODS: All cases that underwent cataract surgeries over a 12-year period (January 2004 to December 2015) were included. The routine use of intracameral cefuroxime at the end of cataract surgery was introduced at our centre after April 2010. All cefuroxime aliquots were prepared by the hospital pharmacy using an aseptic compounding technique...
October 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27533631/evaluation-of-a-pharmacogenetic-educational-toolkit-for-community-pharmacists
#19
Susanne B Haga, Rachel Mills, Jivan Moaddeb
AIM: Over the past several decades, the roles and services of community pharmacists have expanded beyond traditional medical dispensation and compounding, and include health services such as vaccinations, and clinical testing and screening. Incorporating pharmacogenetic (PGx) testing into the menu of pharmacy services is logical and feasible; however, few pharmacists have experience with PGx testing, and few educational resources about PGx are available to support the uptake of PGx testing in community pharmacies...
September 2016: Pharmacogenomics
https://www.readbyqxmd.com/read/27518174/organogels-in-drug-delivery-a-special-emphasis-on-pluronic-lecithin-organogels
#20
Hashem Alsaab, Sindhu Prabha Bonam, Dherya Bahl, Pallabita Chowdhury, Kenneth Alexander, Sai Hs Boddu
Organogels have emerged as an alternative carrier for small and macromolecules via transdermal, oral, rectal and ophthalmic routes. Pluronic lecithin organogels (PLO gels) are lecithin-based organogels widely used in compounding pharmacies as a vehicle for enhancing the transdermal permeability of many therapeutic drugs. However, the scientific and systematic evidence in support of how well PLO gels help in transdermal delivery is scanty. Recently, some clinical studies have reported nearly complete lack of bioavailability of certain topically administered drugs from PLO gels...
April 2016: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
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