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https://www.readbyqxmd.com/read/28107074/analysis-of-the-normal-electrocardiogram-in-wild-rooks-corvus-frugilegus
#1
Hossein Hassanpour, Hossein Abbasi Dehkordi, Mehdi Khosravi, Saeid Soltani, Leila Nasiri
To describe the normal electrocardiographic (ECG) patterns and values in unanesthetized rooks ( Corvus frugilegus ), standard bipolar (I, II, and III) and augmented unipolar limb (aVR, aVL, and aVF) lead ECGs were recorded from 10 clinically healthy wild rooks. Wave forms were analyzed in all leads at 50 mm/s and at 10 mm = 1 mV to determine PR, QRS, ST, and QT durations; the net QRS complex; and P and T amplitudes. The polarity of each waveform was tabulated in all leads. The mean electrical axis (MEA) for the frontal plane was counted by using leads II and III...
December 2016: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28107061/the-evolution-of-reproductive-phenology-in-broadcast-spawners-and-the-maintenance-of-sexually-antagonistic-polymorphism
#2
Colin Olito, Dustin J Marshall, Tim Connallon
Reproductive phenology is a crucial life-history trait that evolves in response to external environmental conditions and frequency- and density-dependent interactions within species. Broadcast spawners-which represent a large fraction of aquatic biodiversity-evolve phenologies that balance strong density-dependent fertilization success against abiotic environmental conditions that are required for successful reproduction. The overall balance between these processes may be particularly complex in dioecious species, where selection on reproductive timing potentially differs between the sexes...
February 2017: American Naturalist
https://www.readbyqxmd.com/read/28106963/wire-skills-for-the-surgeon-femoral-access-safety-net-and-vascular-closure-devices-in-transfemoral-transcatheter-aortic-valve-implantation-procedures
#3
Simon Sndermann, Axel Unbehaun, Alexander Meyer, Volkmar Falk, Jrg Kempfert
Transfemoral transcatheter aortic valve implantation procedures are widely used to treat patients with aortic stenosis and high surgical risk. Major vascular complications are common and are associated with higher mortality rates. We describe the use of vascular access site closure systems and a safety net to prevent and handle these complications.
December 14, 2016: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/28106920/self-admission-to-inpatient-treatment-for-patients-with-anorexia-nervosa-the-patient-s-perspective
#4
Mattias Strand, Cynthia M Bulik, Yvonne von Hausswolff-Juhlin, Sanna A Gustafsson
The aim of the present study was to explore patients' experiences of participating in a self-admission program at a specialist eating disorders clinic. Sixteen adult program participants with a diagnosis of anorexia nervosa were interviewed at 6 months about their experiences in the self-admission program. A qualitative content analysis approach was applied to identify recurring themes. Four themes were identified: Agency and Flexibility, Functions, Barriers, and Applicability. Participants used self-admission to boost healthy behaviors, to prevent deterioration, to forestall the need for longer periods of hospitalizations, and to get a break from overwhelming demands...
January 20, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28106748/two-dimensional-numerical-simulations-of-ultrasound-in-liquids-with-gas-bubble-agglomerates-examples-of-bubbly-liquid-type-acoustic-metamaterials-blamms
#5
Christian Vanhille
This work deals with a theoretical analysis about the possibility of using linear and nonlinear acoustic properties to modify ultrasound by adding gas bubbles of determined sizes in a liquid. We use a two-dimensional numerical model to evaluate the effect that one and several monodisperse bubble populations confined in restricted areas of a liquid have on ultrasound by calculating their nonlinear interaction. The filtering of an input ultrasonic pulse performed by a net of bubbly-liquid cells is analyzed. The generation of a low-frequency component from a single cell impinged by a two-frequency harmonic wave is also studied...
January 17, 2017: Sensors
https://www.readbyqxmd.com/read/28106712/very-low-protein-diet-vlpd-reduces-metabolic-acidosis-in-subjects-with-chronic-kidney-disease-the-nutritional-light-signal-of-the-renal-acid-load
#6
Biagio Raffaele Di Iorio, Lucia Di Micco, Stefania Marzocco, Emanuele De Simone, Antonietta De Blasio, Maria Luisa Sirico, Luca Nardone, On Behalf Of Ubi Study Group
BACKGROUND: Metabolic acidosis is a common complication of chronic kidney disease; current guidelines recommend treatment with alkali if bicarbonate levels are lower than 22 mMol/L. In fact, recent studies have shown that an early administration of alkali reduces progression of CKD. The aim of the study is to evaluate the effect of fruit and vegetables to reduce the acid load in CKD. METHODS: We conducted a case-control study in 146 patients who received sodium bicarbonate...
January 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28106549/the-multimerization-state-of%C3%A2-the%C3%A2-amyloid-%C3%AE-42-amyloid-peptide-governs-its-interaction-network-with%C3%A2-the%C3%A2-extracellular-matrix
#7
Romain Salza, Claire Lethias, Sylvie Ricard-Blum
The goals of this work were i) to identify the interactions of amyloid-β (Aβ)42 under monomeric, oligomeric, and fibrillar forms with the extracellular matrix (ECM) and receptors, ii) to determine the influence of Aβ42 supramolecular organization on these interactions, and iii) to identify the molecular functions, biological processes, and pathways targeted by Aβ42 in the ECM. The ECM and cell surface partners of Aβ42 and its supramolecular forms were identified with protein and glycosaminoglycan (GAG) arrays (81 molecules in triplicate) probed by surface plasmon resonance imaging...
January 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28106470/grace-score-validation-in-predicting-hospital-mortality-analysis-of-the-role-of-sex
#8
Eva de-Miguel-Balsa, Jaime Latour-Pérez, Anna Baeza-Román, Cristina Amorós-Verdú, Juan Antonio Fernández-Lozano
BACKGROUND: The GRACE (Global Registry of Acute Coronary Events) risk score is recommended for risk stratification in acute coronary syndrome (ACS). It does not include sex, a variable strongly associated with ACS prognosis. The aim of this study was to examine if sex adds prognostic information to the GRACE score in a contemporary population. MATERIALS AND METHODS: Analysis of discrimination and calibration of GRACE score in the validation population, derived from the ARIAM-SEMICYUC registry (2012-2015)...
January 20, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28106343/net-clinical-benefit-of-hospitalization-versus-outpatient-management-of-patients-with-acute-pulmonary-embolism
#9
P-M Roy, D J Corsi, M Carrier, A Theogene, C de Wit, C Dennie, G Le Gal, A Delluc, T Moumneh, M Rodger, P Wells, E Gandara
BACKGROUND: The decision to hospitalize or not patients with acute pulmonary embolism (PE) is controversial. Despite the advantages of close monitoring, hospitalization by itself may lead to in-hospital complications and potentially worsen the prognosis of PE patients. OBJECTIVES: To determine the net clinical benefit of hospitalization versus outpatient management of normotensive patients with acute pulmonary embolism (PE). METHODS: Retrospective cohort propensity score analysis (radius marching with replacement)...
January 20, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28106200/bright-conjugated-polymer-nanoparticles-containing-a-biodegradable-shell-produced-at-high-yields-and-with-tuneable-optical-properties-by-a-scalable-microfluidic-device
#10
T F Abelha, T W Phillips, J H Bannock, A M Nightingale, C A Dreiss, E Kemal, L Urbano, J C deMello, M Green, L A Dailey
This study compares the performance of a microfluidic technique and a conventional bulk method to manufacture conjugated polymer nanoparticles (CPNs) embedded within a biodegradable poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) (PEG5K-PLGA55K) matrix. The influence of PEG5K-PLGA55K and conjugated polymers cyano-substituted poly(p-phenylene vinylene) (CN-PPV) and poly(9,9-dioctylfluorene-2,1,3-benzothiadiazole) (F8BT) on the physicochemical properties of the CPNs was also evaluated. Both techniques enabled CPN production with high end product yields (∼70-95%)...
January 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28106147/prediction-of-very-late-arrhythmia-recurrence-after-radiofrequency-catheter-ablation-of-atrial-fibrillation-the-mb-later-clinical-score
#11
Nebojša Mujović, Milan Marinković, Nebojša Marković, Alena Shantsila, Gregory Y H Lip, Tatjana S Potpara
Reliable prediction of very late recurrence of atrial fibrillation (VLRAF) occuring >12 months after catheter ablation (CA) in apparently "cured" patients could optimize long-term follow-up and modify decision-making regarding the discontinuation of oral anticoagulant therapy. In a single-centre cohort of consecutive patients post radiofrequency AFCA, we retrospectively derived a novel score for VLRAF prediction. Of 133 consecutive post AFCA patients (mean age 56.9 ± 11.8 years, 63.9% male, 69.2% with paroxysmal AF) who were arrhythmia-free at 12 months (excluding 3-month "blanking period"), 20 patients expirienced a VLRAF during a 29...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28106048/simulating-the-hydrologic-cycle-in-coal-mining-subsidence-areas-with-a-distributed-hydrologic-model
#12
Jianhua Wang, Chuiyu Lu, Qingyan Sun, Weihua Xiao, Guoliang Cao, Hui Li, Lingjia Yan, Bo Zhang
Large-scale ground subsidence caused by coal mining and subsequent water-filling leads to serious environmental problems and economic losses, especially in plains with a high phreatic water level. Clarifying the hydrologic cycle in subsidence areas has important practical value for environmental remediation, and provides a scientific basis for water resource development and utilisation of the subsidence areas. Here we present a simulation approach to describe interactions between subsidence area water (SW) and several hydrologic factors from the River-Subsidence-Groundwater Model (RSGM), which is developed based on the distributed hydrologic model...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28105921/simba-a-web-tool-for-managing-bacterial-genome-assembly-generated-by-ion-pgm-sequencing-technology
#13
Diego C B Mariano, Felipe L Pereira, Edgar L Aguiar, Letícia C Oliveira, Leandro Benevides, Luís C Guimarães, Edson L Folador, Thiago J Sousa, Preetam Ghosh, Debmalya Barh, Henrique C P Figueiredo, Artur Silva, Rommel T J Ramos, Vasco A C Azevedo
BACKGROUND: The evolution of Next-Generation Sequencing (NGS) has considerably reduced the cost per sequenced-base, allowing a significant rise of sequencing projects, mainly in prokaryotes. However, the range of available NGS platforms requires different strategies and software to correctly assemble genomes. Different strategies are necessary to properly complete an assembly project, in addition to the installation or modification of various software. This requires users to have significant expertise in these software and command line scripting experience on Unix platforms, besides possessing the basic expertise on methodologies and techniques for genome assembly...
December 15, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/28105908/degreecox-a-network-based-regularization-method-for-survival-analysis
#14
André Veríssimo, Arlindo Limede Oliveira, Marie-France Sagot, Susana Vinga
BACKGROUND: Modeling survival oncological data has become a major challenge as the increase in the amount of molecular information nowadays available means that the number of features greatly exceeds the number of observations. One possible solution to cope with this dimensionality problem is the use of additional constraints in the cost function optimization. LASSO and other sparsity methods have thus already been successfully applied with such idea. Although this leads to more interpretable models, these methods still do not fully profit from the relations between the features, specially when these can be represented through graphs...
December 13, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/28105595/bioelectrochemical-anaerobic-sewage-treatment-technology-for-arctic-communities
#15
Boris Tartakovsky, Yehuda Kleiner, Michelle-France Manuel
This study describes a novel wastewater treatment technology suitable for small remote northern communities. The technology is based on an enhanced biodegradation of organic carbon through a combination of anaerobic methanogenic and microbial electrochemical (bioelectrochemical) degradation processes leading to biomethane production. The microbial electrochemical degradation is achieved in a membraneless flow-through bioanode-biocathode setup operating at an applied voltage below the water electrolysis threshold...
January 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28105522/response-of-aboveground-carbon-balance-to-long-term-experimental-enhancements-in-precipitation-seasonality-is-contingent-on-plant-community-type-in-cold-desert-rangelands
#16
Kathryn McAbee, Keith Reinhardt, Matthew J Germino, Andrew Bosworth
Semi-arid rangelands are important carbon (C) pools at global scales. However, the degree of net C storage or release in water-limited systems is a function of precipitation amount and timing, as well as plant community composition. In northern latitudes of western North America, C storage in cold-desert ecosystems could increase with boosts in wintertime precipitation, in which climate models predict, due to increases in wintertime soil water storage that enhance summertime productivity. However, there are few long-term, manipulative field-based studies investigating how rangelands will respond to altered precipitation amount or timing...
January 20, 2017: Oecologia
https://www.readbyqxmd.com/read/28105110/wt1-shrna-delivery-using-transferrin-conjugated-peg-liposomes-in-an-in-vivo-model-of-melanoma
#17
Santiago Saavedra-Alonso, Pablo Zapata-Benavides, Ana Karina Chavez-Escamilla, Edgar Manilla-Muñoz, Diana Elisa Zamora-Avila, Moisés Armides Franco-Molina, Cristina Rodriguez-Padilla
The global incidence of melanoma is increasing. Mortality from melanoma is influenced primarily by metastasis in advanced stages of the disease. Current treatments are largely ineffective; thus, novel gene delivery approaches that target tumor-specific markers may be useful for the treatment of melanoma. Systemic administration of encapsulated RNA-interference plasmids targeted against tumor cells is a potential alternative therapy for cancer. Formulations of transferrin (Tf)-conjugated polyethylene glycol (PEG) liposomes loaded with short hairpin RNA (shRNA) against WT1 (Lip + RNAi + Tf), PEG liposomes loaded with shRNA against WT1 (Lip + RNAi), Tf-conjugated PEG liposomes loaded with pEGFP-N3 (Lip + GFP + Tf) and saline solution as negative control (untreated) were administered systemically to C57BL/6 mice implanted subcutaneously with a melanoma cell line...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28104752/reduced-prosthetic-stiffness-lowers-the-metabolic-cost-of-running-for-athletes-with-bilateral-transtibial-amputations
#18
Owen N Beck, Paolo Taboga, Alena Marie Grabowski
Inspired by the spring-like action of biological legs, running-specific prostheses are designed to enable athletes with lower-limb amputations to run. Yet, manufacturer recommendations for prosthetic stiffness and height may not optimize running performance. Therefore, we investigated the effects of using different prosthetic configurations on the metabolic cost and biomechanics of running. Five athletes with bilateral transtibial amputations each performed fifteen trials on a force-measuring treadmill at 2...
January 19, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28104724/predicting-survival-of-patients-with-small-bowel-neuroendocrine-tumours-comparison-of-3-systems
#19
Ashley Kieran Clift, Omar Faiz, Rob Goldin, John Martin, Harpreet Wasan, Marc-Olaf Liedke, Erik Schloericke, Anna Malczewska, Guido Rindi, Mark Kidd, Irvin Modlin, Andrea Frilling
Neuroendocrine tumours (NET) are clinically challenging due to their unpredictable behaviour. Nomograms, grading and staging systems are predictive tools with multiple roles in clinical practice, including patient prognostication. The NET nomogram allocates scores for various clinicopathological parameters, calculating percentage estimates for 5- and 10-year disease-specific survival of patients with small bowel (SB) NET. We evaluated the clinical utility of three prognostic systems in 70 SB NET patients: the NET nomogram, the World Health Organisation (WHO)/European Neuroendocrine Tumour Society (ENETS) grading system and the American Joint Commission on Cancer (AJCC)/Union Internationale Contre le Cancer (UICC) TNM staging method...
January 19, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28104403/a-model-to-predict-risk-of-blood-transfusion-after-gynecologic-surgery
#20
Jamie Stanhiser, Kevin Chagin, J Eric Jelovsek
BACKGROUND: A model that predicts a patient's risk of receiving a blood transfusion may facilitate selective preoperative testing and more efficient perioperative blood management utilization. OBJECTIVES: To construct and validate a model that predicts a patient's risk of receiving a blood transfusion after gynecologic surgery. STUDY DESIGN: 18,319 women who underwent gynecologic surgery at 10 institutions in a single health system by 116 surgeons between January 2010 and June 2014 were analyzed...
January 16, 2017: American Journal of Obstetrics and Gynecology
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