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https://www.readbyqxmd.com/read/28340317/opportunities-for-crash-and-injury-reduction-a-multi-harm-approach-for-crash-data-analysis
#1
Ann Mallory, Allison Kender, Kevin Moorhouse
OBJECTIVE: A multi-harm approach for analyzing crash and injury data was developed for the ultimate purpose of getting a richer picture of motor vehicle crash outcomes identifying research opportunities in crash safety. METHODS: Methods were illustrated using a retrospective analysis of 69,597 occupant cases from NASS CDS (National Automotive Sampling System Crashworthiness Data System) from 2005 to 2015. Occupant cases were analyzed by frequency and severity of outcome: fatality, injury by AIS (Abbreviated Injury Scale), number of cases, attributable fatality, disability, and injury costs...
March 24, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28334406/male-and-female-cervical-spine-biomechanics-and-anatomy-implication-for-scaling-injury-criteria
#2
Narayan Yoganandan, Cameron R Bass, Liming Voo, Frank A Pintar
There is an increased need to develop female-specific injury criteria and anthropomorphic test devices (dummies) for automotive and military environments, especially as women take occupational roles traditionally reserved for men. Although some exhaustive reviews on the biomechanics and injuries of the human spine have appeared in clinical and bioengineering literatures, focus on the difference between male and female cervical spine responses and characteristics has largely been ignored. Current neck injury criteria for automotive dummies for assessing crashworthiness and occupant safety are obtained from animal and human cadaver experiments, computational modeling and human volunteer studies...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28332863/male-and-female-worldsid-and-post-mortem-human-subject-responses-in-full-scale-vehicle-tests
#3
Narayan Yoganandan, John Humm, Frank Pintar, Heather Rhule, Kevin Moorhouse, Brian Suntay, Jim Stricklin, Rodney Rudd, Matthew Craig
Structured ABSTRACT Objective: To compare the responses of male and female WorldSID dummies with post mortem human subject (PMHS) responses in full-scale vehicle tests. METHODS: Tests were conducted according to the FMVSS-214 protocols and using the United States Side impact New Car Assessment Program change in velocity to match PMHS experiments, published earlier. Moving deformable barrier (MDB) tests were conducted with the male and female surrogates in the left front and left rear seats...
March 23, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28331534/ford-and-edison-in-a-modern-regulatory-environment-the-first-in-human-trial-of-night-work-and-artificial-light
#4
EDITORIAL
Thomas C Erren, David M Shaw, Ursula Wild, J Valérie Groß
A thought experiment places Henry Ford and Thomas Alva Edison in a modern regulatory environment. In a utopian occupational world devoid of night-shifts or artificial light, Ford wants to experiment with "working through the night". To support Ford's project, Edison offers his patented electric lamps to "turn nights into days". An ethics committee [EC] does not approve the night-work experiment and Utopia's Food and Drug Administration [FDA] does not approve the potential medical device as safe for use by humans...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28331120/color-functionality-used-in-visual-display-for-occupational-and-environmental-safety-and-managing-color-vision-deficiency
#5
Nobuhisa Ochiai, Hiroyuki Kondo
The effects of color perception are utilized in visual displays for the purpose of safety in the workplace and in daily life. These effects, generally known as color functionality, are divided into four classifications: visibility, legibility, conspicuity and discriminability. This article focuses on the relationship between the color functionality of color schemes used in visual displays for occupational and environmental safety and color vision deficiency (particularly congenital red-green color deficiency), a critical issue in ophthalmology, and examines the effects of color functionality on the perception of the color red in individuals with protan defects...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/28328293/history-of-knowledge-and-evolution-of-occupational-health-and-regulatory-aspects-of-asbestos-exposure-science-1900-1975
#6
Christy A Barlow, Jennifer Sahmel, Dennis J Paustenbach, John L Henshaw
The understanding by industrial hygienists of the hazards of asbestos and appropriate ways to characterize and control exposure has evolved over the years. Here, a detailed analysis of the evolution of industrial hygiene practices regarding asbestos and its health risks, from the early 1900s until the advent of the national occupational health and safety regulatory structure currently in place in the US (early-to-mid 1970s) is presented. While industrial hygienists recognized in the early 1900s that chronic and high-level exposures to airborne concentrations of asbestos could pose a serious health hazard, it was not until the mid-1950s that the carcinogenic nature of asbestos began to be characterized and widespread concern followed...
March 22, 2017: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/28327081/pilot-study-of-patron-sound-level-exposure-in-loud-restaurants-bars-and-clubs-in-new-york-city
#7
Ariel Spira-Cohen, Anna Caffarelli, Lawrence Fung
Visiting restaurants, bars, clubs and lounges is a regular part of urban cultural life for residents and tourists alike; however, anecdotal reports and diner surveys suggest that sound levels are excessive and diners dislike them. High sound levels in these venues can contribute to both patron and employee overexposure, and young people may be particularly at risk. To supplement the paucity of literature and data on noise in urban venues, patron noise exposure was measured inside a sample of loud New York City (NYC) restaurants, bars, clubs and lounges...
March 22, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28326998/effects-of-organizational-safety-practices-and-perceived-safety-climate-on-ppe-usage-engineering-controls-and-adverse-events-involving-liquid-antineoplastic-drugs-among-nurses
#8
David M DeJoy, Todd D Smith, Henok Woldu, Mari-Amanda Dyal, Andrea L Steege, James M Boiano
PURPOSE: Antineoplastic drugs pose risks to the healthcare workers who handle them. This fact notwithstanding, adherence to safe handing guidelines remains inconsistent and often poor. This study examined the effects of pertinent organizational safety practices and perceived safety climate on the use of personal protective equipment, engineering controls, and adverse events (spill/leak or skin contact) involving liquid antineoplastic drugs Method: Data for this study came from the 2011 National Institute for Occupational Safety and Health (NIOSH) Health and Safety Practices Survey of Healthcare Workers which included a sample of approximately 1,800 nurses who had administered liquid antineoplastic drugs during the past seven days...
March 22, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28323582/white-matter-integrity-in-high-altitude-pilots-exposed-to-hypobaria
#9
Stephen A McGuire, Goldie R E Boone, Paul M Sherman, David F Tate, Joe D Wood, Beenish Patel, George Eskandar, S Andrea Wijtenburg, Laura M Rowland, Geoffrey D Clarke, Patrick M Grogan, John H Sladky, Peter V Kochunov
INTRODUCTION: Nonhypoxic hypobaric (low atmospheric pressure) occupational exposure, such as experienced by U.S. Air Force U-2 pilots and safety personnel operating inside altitude chambers, is associated with increased subcortical white matter hyperintensity (WMH) burden. The pathophysiological mechanisms underlying this discrete WMH change remain unknown. The objectives of this study were to demonstrate that occupational exposure to nonhypoxic hypobaria is associated with altered white matter integrity as quantified by fractional anisotropy (FA) measured using diffusion tensor imaging and relate these findings to WMH burden and neurocognitive ability...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28320775/is-it-time-to-reassess-current-safety-standards-for-glyphosate-based-herbicides
#10
REVIEW
Laura N Vandenberg, Bruce Blumberg, Michael N Antoniou, Charles M Benbrook, Lynn Carroll, Theo Colborn, Lorne G Everett, Michael Hansen, Philip J Landrigan, Bruce P Lanphear, Robin Mesnage, Frederick S Vom Saal, Wade V Welshons, John Peterson Myers
Use of glyphosate-based herbicides (GBHs) increased ∼100-fold from 1974 to 2014. Additional increases are expected due to widespread emergence of glyphosate-resistant weeds, increased application of GBHs, and preharvest uses of GBHs as desiccants. Current safety assessments rely heavily on studies conducted over 30 years ago. We have considered information on GBH use, exposures, mechanisms of action, toxicity and epidemiology. Human exposures to glyphosate are rising, and a number of in vitro and in vivo studies challenge the basis for the current safety assessment of glyphosate and GBHs...
March 20, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28317872/preclinical-evaluation-of-the-efficacy-pharmacokinetics-and-immunogenicity-of-js-001-a-programmed-cell-death-protein-1-pd-1-monoclonal-antibody
#11
Jie Fu, Fang Wang, Li-Hou Dong, Jing Zhang, Cheng-Lian Deng, Xue-Li Wang, Xin-Yao Xie, Jing Zhang, Ruo-Xian Deng, Li-Bo Zhang, Hai Wu, Hui Feng, Bo Chen, Hai-Feng Song
JS-001 is the first monoclonal antibody (mAb) against programmed cell death protein-1 (PD-1) approved by the China Food and Drug Administration (CFDA) into the clinical trails. To date, however, no pre-clinical pharmacological and pharmacokinetic (PK) data are available. In this study, we investigated the efficacy of JS-001 and conducted a preclinical PK study, including the monitoring of anti-drug antibodies (ADAs). We found that JS-001 specifically bound to PD-1 antigen with an EC50 of 21 nmol/L, and competently blocked the binding of PD-1 antigen to PD-L1 and PD-L2 with IC50 of 3...
March 20, 2017: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/28315643/benefits-of-21-oxygen-compared-with-100-oxygen-for-delivery-of-isoflurane-to-mice-mus-musculus-and-rats-rattus-norvegicus
#12
Laura A Wilding, Joe A Hampel, Basma M Khoury, Stacey Kang, David Machado-Aranda, Krishnan Raghavendran, Jean A Nemzek
At research institutions, isoflurane delivered by precision vaporizer to a face mask is the standard for rodent surgery and for procedures with durations that exceed a few minutes. Pure oxygen is often used as the carrier gas for isoflurane anesthesia, despite documented complications from long-term 100% oxygen use in humans and known occupational safety risks. We therefore examined the effect of anesthetic delivery gas on physiologic variables in mice and rats. Rodents were anesthetized for 60 min with isoflurane delivered in either 21% or 100% oxygen by means of a nose cone...
March 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28314636/comparing-non-safety-with-safety-device-sharps-injury-incidence-data-from-two-different-occupational-surveillance-systems
#13
A H Mitchell, G B Parker, H Kanamori, W A Rutala, D J Weber
The United States Occupational Safety and Health Administration (OSHA) Bloodborne Pathogens Standard as amended by the Needlestick Safety and Prevention Act requiring the use of safety-engineered medical devices to prevent needlesticks and sharps injuries has been in place since 2001. Injury changes over time include differences between those from non-safety compared with safety-engineered medical devices. This research compares two US occupational incident surveillance systems to determine whether these data can be generalized to other facilities and other countries either with legislation in place or considering developing national policies for the prevention of sharps injuries among healthcare personnel...
February 27, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28306758/the-association-between-blood-lead-levels-and-cardiovascular-diseases-among-lead-exposed-male-workers
#14
Young-Sun Min, Yeon-Soon Ahn
Objective We prospectively evaluated the association between blood lead levels (BLL) and increases in hospital admissions for treatment of cardiovascular diseases among lead-exposed workers in Korea. Methods The study cohort was derived from Korea Occupational Safety and Health Agency data, which included lead-exposed male workers who underwent lead-associated medical check-ups at least once between 2000 and 2004. The hospital adjusted admission hazard ratio (AHR) of cardiovascular diseases for each BLL grade (10-20 and ≥20 μg/dL) was compared with that of the reference grade (<10 μg/dL) using Cox's proportional hazard models...
March 17, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28300965/collective-strategy-for-facing-occupational-risks-of-a-nursing-team
#15
Marli Maria Loro, Regina Célia Gollner Zeitoune
OBJECTIVE: To socialize an educational action through the process of group discussion and reflection, with the aim to increase the care of nursing workers in facing occupational risks. METHOD: A qualitative descriptive study using the Convergent Care Research modality with nursing staff working in an emergency department of a hospital in the northwest region of the state of Rio Grande do Sul, Brazil. Data collection was carried out through educational workshops and information was processed using content analysis, resulting in two thematic categories: A look at the knowledge and practices about occupational risks in nursing; and adherence to protective measures by the nursing team against occupational risks...
March 9, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28299449/contribution-of-job-exposure-matrices-for-exposure-assessment-in-occupational-safety-and-health-monitoring-systems-application-from-the-french-national-occupational-disease-surveillance-and-prevention-network
#16
Arnaud Florentin, Denis Zmirou-Navier, Christophe Paris
OBJECTIVES: To detect new hazards ("signals"), occupational health monitoring systems mostly rest on the description of exposures in the jobs held and on reports by medical doctors; these are subject to declarative bias. Our study aims to assess whether job-exposure matrices (JEMs) could be useful tools for signal detection by improving exposure reporting. METHODS: Using the French national occupational disease surveillance and prevention network (RNV3P) data from 2001 to 2011, we explored the associations between disease and exposure prevalence for 3 well-known pathology/exposure couples and for one debatable couple...
March 16, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28299214/occupational-neurobrucellosis-mimicking-a-brain-tumor-a-case-report-and-review-of-the-literature
#17
Hussein Algahtani, Bader Shirah, Dina Abdulghani, Roiya Farhan, Raghad Algahtani
Brucellosis is a zoonotic bacterial infection which is transmitted to humans from infected animals and is endemic in many parts of the world including Saudi Arabia. In this article, we report a case of occupational neurobrucellosis that presented with a space-occupying lesion mimicking a brain tumor. We stress on the importance of obtaining detailed social history including occupation to reach the diagnosis in several conditions including brucellosis. We also stress on taking universal precautions when handling any specimens...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28296431/does-unbelted-safety-requirement-affect-protection-for-belted-occupants
#18
Jingwen Hu, Kathleen D Klinich, Miriam A Manary, Carol A C Flannagan, Prabha Narayanaswamy, Matthew P Reed, Margaret Andreen, Mark Neal, Chin-Hsu Lin
OBJECTIVE: Federal regulations in the United States require vehicles to meet occupant performance requirements with unbelted test dummies. Removing the test requirements with unbelted occupants might encourage the deployment of seatbelt interlocks and allow restraint optimization to focus on belted occupants. The objective of this study is to compare the performance of restraint systems optimized for belted only occupants with those optimized for both belted and unbelted occupants using computer simulations and field crash data analyses...
March 15, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28292698/fatal-falls-and-pfas-use-in-the-construction-industry-findings-from-the-niosh-face-reports
#19
Xiuwen Sue Dong, Julie A Largay, Sang D Choi, Xuanwen Wang, Chris Trahan Cain, Nancy Romano
This study analyzed the Construction FACE Database (CFD), a quantitative database developed from reports of the Fatality Assessment and Control Evaluation (FACE) program conducted by the National Institute for Occupational Safety and Health (NIOSH). The CFD contains detailed data on 768 fatalities in the construction industry reported by NIOSH and individual states from 1982 through June 30, 2015. The results show that falls accounted for 42% (325) of the 768 fatalities included in the CFD. Personal fall arrest systems (PFAS) were not available to more than half of the fall decedents (54%); nearly one in four fall decedents (23%) had access to PFAS, but were not using it at the time of the fall...
March 11, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28288732/evaluation-of-the-five-year-bloomberg-philanthropies-global-road-safety-program-in-the-russian-federation
#20
S Gupta, N Paichadze, E Gritsenko, V Klyavin, E Yurasova, A A Hyder
Road traffic injuries are a leading cause of morbidity and mortality in the world. In Russia, a road safety program was implemented in Lipetskaya and Ivanovskaya oblasts (regions) as part of a 10-country effort funded by Bloomberg Philanthropies. The program was focused on increasing seat belt and child restraint use and reducing speeding. The primary goals of this monitoring and evaluation study are to assess trends in seat belt use, child restraint use, and speed compliance in the two oblasts over the 5 years and to explore the overall impact of the program on road traffic injury and death rates...
March 2017: Public Health
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