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Rheumatic valve replacement

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https://www.readbyqxmd.com/read/27931546/maternal-and-fetal-outcomes-in-pregnant-women-undergoing-balloon-mitral-valvotomy-for-rheumatic-mitral-stenosis
#1
Desabandhu Vinayakumar, G V Vinod, Suresh Madhavan, Mangalath Narayanan Krishnan
BACKGROUND: Rheumatic mitral stenosis constitutes a major cause of acquired heart disease complicating pregnancy in India. In the present study, we have studied the fetal and maternal outcomes of women undergoing balloon mitral valvotomy during pregnancy. METHODS AND RESULTS: 49 pregnant ladies were included in this study in whom balloon mitral valvotomy was performed. The mean age of these patients was 25.7±3.1 years. The mean gestational age was 23.5±5.2 weeks (12-36 weeks)...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27928260/emergency-redo-mitral-valve-replacement-immediately-after-caesarean-section
#2
İbrahim Duvan, Ümit Pınar Sungur, Burak Emre Onuk, Mehmet Şanser Ateş, İbrahim Sami Karacan, Murat Kurtoğlu
Surgery for heart diseases during pregnancy, especially necessitating cardiopulmonary bypass, is believed to trigger maternal and fetal risks and should be performed only when medical therapy has been unsuccessful to alleviate the cardiac decompensation. A 33-year-old pregnant woman in her 33rd week of gestation was admitted to our hospital. She had rheumatic mitral valvular stenosis and had undergone mitral valve replacement (MVR) with a mechanical prosthesis 11 years earlier in another center. Echocardiography revealed a thrombotic mass obstructing the leaflets of the mechanical mitral valve...
April 13, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/27876696/stroke-prevention-strategies-in-patients-with-atrial-fibrillation-and-heart-valve-abnormalities-perceptions-of-valvular-atrial-fibrillation-results-of-the-european-heart-rhythm-association-survey
#3
Tatjana S Potpara, Gregory Y H Lip, Torben B Larsen, Antonio Madrid, Dan Dobreanu, Ewa Jędrzejczyk-Patej, Nikolaos Dagres
The purpose of this European Heart Rhythm Association (EHRA) Survey was to assess the perceptions of 'valvular' atrial fibrillation (AF) and management of AF patients with various heart valve abnormalities in daily clinical practice in European electrophysiology (EP) centres. Questionnaire survey was sent via the Internet to the EHRA-EP Research Network Centres. Of the 52 responding centres, 42 (80.8%) were university hospitals. Choosing the most comprehensive definition of valvular AF, a total of 49 centres (94...
October 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27868419/-research-progress-on-pharmacotherapy-of-calcific-aortic-valve-disease
#4
Miaomiao DU, Gaigai Ma, Yuping Shi
With the population aging and declining incidence of rheumatic heart disease, calcific aortic valve disease (CAVD) has become the most frequent valve disease and the common cause of aortic valve replacement. Patients with CAVD need to cope with a deteriorating quality of life and valve replacement is the only effective clinical option for the patients. Therefore, early pharmacotherapy is of great significance in prevention or slow-down of the progression of CAVD. For years CAVD was considered to be a passive wear and tear process of valves, but now it is recognized as an active and multi-factorial process...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/27848007/transcatheter-tricuspid-valve-in-valve-replacement-one-year-results-alternative-to-surgery-in-high-risk-patients
#5
João Mesquita, Rui Campante Teles, José Pedro Neves, João Abecasis, Pedro Carmo, João Brito, Miguel Abecasis, Manuel Sousa Almeida, Marisa Trabulo, Regina Ribeiras, Ricardo Seabra-Gomes, Miguel Mendes
Although rheumatic heart disease is becoming uncommon in industrialized countries, its global burden is still significant. We report the case of a 70-year-old male with rheumatic heart disease, who underwent 4 previous heart valve replacement surgeries, and presented to our hospital with refractory heart failure (NYHA functional class IV) due to severe stenosis of a previously implanted tricuspid bioprosthesis. The Heart Team deemed the patient as inoperable/high-risk for surgery. As an alternative, a transcatheter tricuspid valve-in-valve replacement was decided upon and later executed through the right femoral vein, with the insertion of an Edwards SAPIEN XT 29 no...
November 15, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27842683/allografts-in-aortic-position-insights-from-a-27-year-single-center-prospective-study
#6
Bardia Arabkhani, Jos A Bekkers, Eleni-Rosalina Andrinopoulou, Jolien W Roos-Hesselink, Johanna J M Takkenberg, Ad J J C Bogers
OBJECTIVE: Over the past decades, the indication for allograft implantation in aortic position has evolved. The purpose of this study is to report long-term survival, allograft durability, and potential risk factors. METHODS: Between 1987 and 2010, 353 patients underwent aortic valve replacements via allograft (92 subcoronary, 261 root replacement; 98% aortic allografts). Patient characteristics, survival, valve durability, and valve-related events were analyzed...
December 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27773402/spectrum-of-congenital-mitral-valve-abnormalities-associated-with-solitary-undifferentiated-papillary-muscle-in-adults
#7
Jagdish C Mohan, Madhu Shukla, Vishwas Mohan, Arvind Sethi
BACKGROUND: Congenital anomaly wherein the mitral valve leaflets are directly attached to the papillary muscle(s) (PM) with or without short under-developed chords is rarely reported in adults. Patients with two PMs with an intervening fibrous bridge have also been included under this head in previous studies. METHODS: Echocardiography enables accurate evaluation of the morphology and function of valve leaflets, chordae tendineae, and PM. This report describes a series of six patients aged 56-84 years who had abnormal mitral valve with a large solitary and anomalously inserted PM seen over a period of 3 years...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27753898/os-01-07-clinical-importance-of-collagen-metabolism-markers-in-rheumatic-heart-valve-disease-in-indian-subpopulation
#8
Tanima Banerjee, Somaditya Mukherjee, Sudip Ghosh, Monodeep Biswas, Santanu Datta, Sanjib Pattari, Shelly Chatterjee, Arun Bandyopadhyay
OBJECTIVE: Rheumatic Heart Disease (RHD), a chronic acquired heart disorder results from Acute Rheumatic Fever. RHD is mostly prevalent in developing nations which is mainly diagnosed by transthoracic echocardiography. Till date, there is no biochemical marker for disease management. In the present study we aim to investigate whether mitral valve remodeling contributes to altered levels of circulating biomarkers of collagen metabolism in rheumatic heart disease. DESIGN AND METHOD: The study involved RHD subjects with before and after valve replacement surgery which includes age and sex matched controls...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27751265/right-atrial-myxoma-clinically-mimicking-recurrence-of-rheumatic-valve-disease-long-time-after-mitral-valve-repair
#9
Gauranga Majumdar, Surendra Agarwal, Shantanu Pande, Satyendra Tewari
Right atrial myxomas are rare. Its occurrence in a previously operated patient of rheumatic mitral stenosis posed clinical diagnostic challenge. We herein report a case of right atrial myxoma who had undergone mitral valve repair 20 years ago and now presented in congestive heart failure. The tumor was arising from the ostium of the coronary sinus and prolapsed into the right ventricle causing significant right ventricular inflow and outflow obstruction. Urgent repeat cardiac surgery was successfully performed to remove the tumor along with mitral valve replacement...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27738481/prognostic-importance-of-exercise-brain-natriuretic-peptide-in-asymptomatic-chronic-organic-severe-mitral-regurgitation-an-observational-study
#10
Santosh Kumar Sinha, Shalini Garg, Ramesh Thakur, Vinay Krishna, Karandeep Singh, Mohit Sachan, Amit Goel, Mahamdula Razi, Umeshwar Pandey, Chandra Mohan Varma
BACKGROUND: The optimal timing of surgery in patients with chronic organic severe mitral regurgitation (MR) continues to be debated, especially for those who are asymptomatic. The aim of the study was to determine independent and additive prognostic value of exercise brain natriuretic peptide (eBNP) in patients with severe asymptomatic MR and normal left ventricular ejection fraction (LVEF). METHODS: Two hundred twenty-three consecutive patients with severe MR defined by effective regurgitant orifice (ERO) area ≥ 40 mm(2) and/or residual volume ≥ 60 mL, LVEF > 60%, and normal LV end-systolic diameter < 40 mm underwent symptom limited exercise treadmill test (TMT)...
November 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27716555/long-term-outcomes-of-catheter-ablation-of-atrial-fibrillation-post-cardiac-valve-replacement
#11
Liang Zhao, Kai Xu, Weifeng Jiang, Li Zhou, Yuanlong Wang, Xiaodong Zhang, Shaohui Wu, Daoliang Zhang, Xu Liu
OBJECTIVE: The long-term outcomes of catheter ablation of atrial fibrillation (AF) developing post-cardiac valve replacement (VR) remain undefined. METHODS AND RESULTS: Eighty-nine post-VR patients with AF (44% longstanding persistent AF, LSP-AF) were enrolled. Cumulative success rate of circumferential pulmonary vein ablation (CPVA for paroxysmal AF) and bidirectional block of lines and disappearance of complex fractionated atrial electrograms (CFAEs for persistent and LSP-AF) as index and repeat procedural endpoints reached 57% (mean, 1...
October 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27698759/delayed-protective-effect-of-telmisartan-on-lung-ischemia-reperfusion-injury-in-valve-replacement-operations
#12
Yongfeng Fan, Daguo Zhang, Daokang Xiang
The present study aimed to investigate the delayed protective effect of telmisartan on lung ischemic/reperfusion injury in patients undergoing heart valve replacement operations. In total, 180 patients diagnosed with rheumatic valve diseases were randomly divided into the telmisartan (T), captopril (C) and placebo (P) groups. In the telmisartan group, the patients were pretreated with telmisartan (1 mg/kg/day), at the time period 96-48 h before the operation, whereas in the C group, the patients were treated with captopril (1 mg/kg/day) at the time period 96-48 h prior to the operation control group...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27667121/differences-in-atrial-fibrillation%C3%A2-associated-proteins-between-the-left-and-right-atrial-appendages-from-patients-with-rheumatic-mitral-valve-disease-a-comparative-proteomic-analysis
#13
Hai Liu, Guangxian Chen, Hongsheng Zheng, Han Qin, Mengya Liang, Kangni Feng, Zhongkai Wu
The majority of proteomic studies have focused on identifying atrial fibrillation (AF)-associated proteins in the right atrium (RA), thus potential differences in AF‑associated proteins between the RA and left atrium (LA) remain unknown. The aim of the present study was to perform proteomic analysis to compare the potential differences in AF‑associated proteins between the right atrial appendage (RAA) and left atrial appendage (LAA) in patients with rheumatic mitral valve disease (RMVD). RAA and LAA tissues were obtained from 18 patients with RMVD (10 with AF) during mitral valve replacement surgery...
November 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27643581/mast-cells-might-have-a-protective-role-against-the-development-of-calcification-and-hyalinisation-in-severe-aortic-valve-stenosis
#14
A Milutinovic, D Petrovič, M Zorc, O Vraspir Porenta, M Arko, A Pleskovič, A Alibegovic, R Zorc-Pleskovic
Aortic valve stenosis is characterized by inflammation and extracellular matrix remodelling. The aim of this study was to analyse the impact of mast cells on the occurrence of histopathological changes of aortic valves in patients with severe grade, non-rheumatic degenerative aortic valve stenosis. Valve specimens were obtained from 38 patients undergoing valve replacement. The role of mast cells was analysed by dividing the specimens into two groups, characterized by the presence (group A, N = 13) or absence of mast cells (group B, N = 25)...
2016: Folia Biologica (Praha)
https://www.readbyqxmd.com/read/27643244/os-01-07-clinical-importance-of-collagen-metabolism-markers-in-rheumatic-heart-valve-disease-in-indian-subpopulation
#15
Tanima Banerjee, Somaditya Mukherjee, Sudip Ghosh, Monodeep Biswas, Santanu Datta, Sanjib Pattari, Shelly Chatterjee, Arun Bandyopadhyay
OBJECTIVE: Rheumatic Heart Disease (RHD), a chronic acquired heart disorder results from Acute Rheumatic Fever. RHD is mostly prevalent in developing nations which is mainly diagnosed by transthoracic echocardiography. Till date, there is no biochemical marker for disease management. In the present study we aim to investigate whether mitral valve remodeling contributes to altered levels of circulating biomarkers of collagen metabolism in rheumatic heart disease. DESIGN AND METHOD: The study involved RHD subjects with before and after valve replacement surgery which includes age and sex matched controls...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27626323/minimally-invasive-transcatheter-aortic-valve-implantation-for-the-treatment-of-rheumatic-heart-disease-in-developing-countries
#16
Trust Saidi, Tania S Douglas
The treatment of rheumatic heart disease presents a medical and surgical challenge, particularly in developing countries, where the disease is prevalent. Most of these countries find it prohibitively expensive to import heart valve prostheses that are required for treatment and are largely manufactured in the United States and Europe. Even if the valves were available, the absence of facilities to conduct open-heart surgery for valve replacement results in many people from developing countries dying needlessly of the disease...
October 2016: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/27569824/myocardial-protective-effects-of-l-carnitine-on-ischemia-reperfusion-injury-in-patients-with-rheumatic-valvular-heart-disease-undergoing-cardiac-surgery
#17
Ming Li, Li Xue, Haifeng Sun, Suochun Xu
OBJECTIVES: The authors used L-carnitine as an ingredient in cardioplegic solution during valve replacement surgery to investigate the protective effect of L-carnitine on myocardial ischemia-reperfusion injury (MIRI) and its possible mechanism. DESIGN: Prospective, randomized study. SETTING: A tertiary-care hospital. PARTICIPANTS: The study comprised 90 patients undergoing valve replacement under cardiopulmonary bypass...
December 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27545612/isolated-rheumatic-severe-tricuspid-regurgitation
#18
Anjith Vupputuri, Vikrant Vijan, Mukund A Prabhu, Rajesh Thachathodiyl, Rajiv Chandrasekharan Nair
Severe isolated tricuspid regurgitation (TR) is very rare, with most cases of TR being functional and secondary to pulmonary hypertension from left heart pathologies. We report an unusual case of a young Nigerian male, who presented to us with dyspnea, repeated hospital admissions for heart failure, and a childhood history of rheumatic fever. Echocardiogram showed massively dilated right atrium and ventricle, noncoaptation of thickened tricuspid valve with torrential free tricuspid regurgitation. Other valves were normal...
November 2016: Echocardiography
https://www.readbyqxmd.com/read/27499950/a-20-year-study-on-treating-childhood-infective-endocarditis-with-valve-replacement-in-a-single-cardiac-center-in-china
#19
Jian Xiao, Liang Yin, Yiyun Lin, Yufeng Zhang, Lihui Wu, Zhinong Wang
BACKGROUND: Children with infective endocarditis (IE) have to undergo valve replacement instead of valve repair in China due to severe valve damage. The present study is to review our experience on surgical treatment of children with IE in reference to the incidence, pathologic status, diagnosis, surgical strategies and outcomes. METHODS: We reviewed 35 patients with a mean age of 13.7±2.2 years who were underwent valve replacement surgery for IE during the period from January 1993 to December 2013...
July 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27476223/cardiac-surgery-for-valvular-heart-disease-at-a-referral-hospital-in-ethiopia-a-review-of-cases-operated-in-the-last-30-years
#20
Senbeta Guteta, Dejuma Yadeta, Aklilu Azazh, Dufera Mekonnen
BACKGROUND: Valvular heart disease has been a significant cause of heart disease worldwide. In Ethiopia, it particularly affects young individuals and constitutes the major cause of cardiovascular disease. Factors associated with choice of treatment for advanced valvular heart disease are variable. The objective of this study is to review surgery done for Ethiopian patients with valvular heart disease. METHODS: We analyzed data on patients who had valve surgery and follow-up at the Tikur Anbessa Specialized Hospital cardiology unit...
April 2016: Ethiopian Medical Journal
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