keyword
https://read.qxmd.com/read/38547236/volumetric-quantification-identifies-some-left-atrial-dilations-undetected-by-left-atrium-aorta-ratio-measurements-a-prospective-echocardiographic-study-in-155-cavalier-king-charles-spaniels-with-and-without-degenerative-mitral-valve-disease
#1
JOURNAL ARTICLE
Valérie Chetboul, Camille Poissonnier, Pierre Foulex, Maria Paz Alvarado, Émilie Trehiou-Sechi, Vittorio Saponaro, Peggy Passavin, Loïc Desquilbet
INTRODUCTION: Degenerative mitral valve disease (DMVD) is the most common canine heart disease with a high predisposition in Cavalier King Charles Spaniels (CKCSs). Mitral regurgitation related to DMVD can lead to left atrial (LA) dilation, which is associated with survival time. Left-atrial-to-aortic (LA:Ao) ratio assessed by two-dimensional echocardiography is commonly used to evaluate LA size. The objectives of this prospective observational study were therefore 1) to compare different echocardiographic methods (i...
2024: PloS One
https://read.qxmd.com/read/38547048/transcatheter-aortic-valve-replacement-in-a-patient-with-quadricuspid-aortic-valve-stenosis-and-regurgitation
#2
JOURNAL ARTICLE
Solomon W Bienstock, Parasuram Krishnamoorthy, Gilbert H L Tang, Stamatios Lerakis, Samin K Sharma, Annapoorna S Kini, Lucy M Safi
We report the case of an 80-year-old woman with known quadricuspid aortic valve (QAV), severe aortic stenosis, and moderate-to-severe regurgitation who recently underwent a transcatheter aortic valve replacement (TAVR).
March 26, 2024: Journal of Invasive Cardiology
https://read.qxmd.com/read/38546351/loss-of-ceramide-synthase-5-inhibits-the-development-of-experimentally-induced-aortic-valve-stenosis
#3
JOURNAL ARTICLE
Laurine Reese, Sven Thomas Niepmann, Philip Düsing, Lea Hänschke, Thomas Beiert, Sebastian Zimmer, Georg Nickenig, Reinhard Bauer, Felix Jansen, Andreas Zietzer
AIM: Inflammation and calcification are hallmarks in the development of aortic valve stenosis (AVS). Ceramides mediate inflammation and calcification in the vascular tissue. The highly abundant d18:1,16:0 ceramide (C16) has been linked to increased cardiovascular mortality and obesity. In this study, we investigate the role of ceramide synthase 5 (CerS5), a critical enzyme for C16 ceramide synthesis, in the development of AVS, particularly in conjunction with a high-fat/high-cholesterol diet (Western diet, WD)...
March 28, 2024: Acta Physiologica
https://read.qxmd.com/read/38546330/coronary-artery-disease-assessment-via-on-site-ct-fractional-flow-reserve-in-patients-undergoing-transcatheter-aortic-valve-replacement
#4
JOURNAL ARTICLE
Alexandra Steyer, Valentina O Puntmann, Eike Nagel, David M Leistner, Vitali Koch, Mariuca Vasa-Nicotera, Parveen Kumar, Christian Booz, Thomas J Vogl, Silvia Mas-Peiro, Simon S Martin
Purpose To examine the clinical feasibility of workstation-based CT fractional flow reserve (CT-FFR) for coronary artery disease (CAD) evaluation during preprocedural planning in patients undergoing transcatheter aortic valve replacement (TAVR). Materials and Methods In this retrospective single-center study, 434 patients scheduled for TAVR between 2018 and 2020 were screened for study inclusion; a relevant proportion of patients (35.0% [152 of 434]) was not suitable for evaluation due to insufficient imaging properties...
April 2024: Radiology. Cardiothoracic imaging
https://read.qxmd.com/read/38545668/balloon-rupture-during-transcatheter-aortic-valve-replacement
#5
REVIEW
Craig Basman, David Landers, Chad Kliger, Karla Rodriguez-Barragan, Sung-Han Yoon, Haroon Faraz, Ankitkumar Patel, Yuriy Dudiy, Mark Anderson, Ryan Kaple
A distinctive complication with balloon-expandable (BE) THV platforms such as the Edwards Sapien (Edwards Lifescience) is the possibility of balloon rupture during THV deployment. Balloon rupture is a rare occurrence that can result in stroke due to fragment embolism, incomplete THV expansion, and/or vascular injury upon retrieval of the balloon. Careful evaluation of preoperative computed tomography is essential to identify high-risk cases. While annular and left ventricular outflow tract (LVOT) calcification are widely acknowledged as common risks for balloon injury, it's essential to note that balloon injury can manifest at various anatomical sites...
March 28, 2024: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/38545630/quantifying-cardiac-dysfunction-and-valvular-heart-disease-associated-with-subretinal-drusenoid-deposits-in-age-related-macular-degeneration
#6
JOURNAL ARTICLE
Yang Fei, Jason J Jo, Sophie Chen, Gerardo Ledesma-Gil, Oscar Otero-Marquez, Emanuel Mordechav, Brandon Le, Yuehong Tong, Katy Tai, Gareth Lema, Richard B Rosen, Vikram Vedprakash Agarwal, Roland Theodore Smith
BACKGROUND/AIMS: Demonstrate through objective multidisciplinary imaging that subretinal drusenoid deposits (SDDs) in age-related macular degeneration (AMD) are linked to both coexistent valvular heart disease (VHD) and reduced systemic perfusion via cardiac index (CI). METHODS: Post-hoc analysis of cross-sectional study. 200 intermediate AMD (iAMD) subjects were assigned by masked readers to two groups: SDD (with or without drusen) and drusen (only) based on multimodal ophthalmic imaging...
March 28, 2024: European Journal of Ophthalmology
https://read.qxmd.com/read/38545505/abelacimab-a-leap-forward-in-anticoagulation-with-fxi-and-fxia-inhibition
#7
REVIEW
Hisham A Badreldin, Nada Alsuhebany, Mohammed Alzahrani, Abdulmajeed M Alshehri, Maha Aldoughaim, Saleh Alqifari, Omar Yassin, Lama Alfehaid, Tariq Alqahtani
Direct Oral Anticoagulants (DOACs) have revolutionized the treatment of thromboembolic disorders, offering targeted, effective, and safer alternatives to traditional anticoagulants like heparins and vitamin K antagonists (VKAs). Despite their benefits, DOACs have drawbacks, including an increased risk of gastrointestinal bleeding and unsuitability for patients with mechanical heart valves. Recent research has highlighted Factor XI (FXI) as a promising anticoagulation target due to its significant role in pathological thrombosis and minor involvement in normal hemostasis...
2024: Curr Res Pharmacol Drug Discov
https://read.qxmd.com/read/38545365/management-options-of-valvular-heart-diseases-after-heart-transplantation-a-scoping-review
#8
REVIEW
Ogulcan Yilmaz, Niamh M Keenan
BACKGROUND: This study aimed to outline the valvular changes following heart transplantation and describe the management options to address these conditions. METHODS: A literature search using EMBASE, MEDLINE, and PubMed databases was performed in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines in this study. Clinical studies involving patients who had their first heart transplant and articles that mentioned management for valvular heart disease were included...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545364/anomalous-origin-of-left-coronary-artery-from-the-pulmonary-artery-our-30-years-of-surgical-experience-and-outcomes
#9
JOURNAL ARTICLE
Chaganti Yogi Sundara Rao, A Aravind, Desai Nelam
Background: The aim of this study was to evaluate our 30 years of surgical experience and outcomes in management of anomalous origin of left coronary artery from the pulmonary artery with various age groups. Methods: Between March 1992 and August 2022, a total of 21 patients (10 males, 11 females; mean age: 16.3±15.9 years; range, 1 to 64 years) diagnosed with anomalous origin of left coronary artery from the pulmonary artery who underwent successful surgical repair were retrospectively analyzed. An initial diagnosis was made with two-dimensional echocardiography...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545352/early-onset-marfan-syndrome-with-aortic-dilatation-and-giant-pulmonary-artery-aneurysm-a-case-report
#10
Qian-Nan Zhang, Feng-Li Xu, Shan-Shan Shi
A 30-year-old woman with ankylosing spondylitis was referred to our clinic with abnormal fetal echocardiography findings, including ascending aortic dilatation, giant main pulmonary artery aneurysm, and aortic and pulmonary valve stenosis at 22 weeks of gestation. The full-term male neonate was born by cesarean section and was transferred to the cardiac intensive care unit soon after delivery for respiratory distress with low percutaneous oxygen saturation. Based on cardiovascular and genetic analysis findings, the patient was diagnosed with Marfan syndrome...
January 2024: Türk Göğüs Kalp Damar Cerrahisi Dergisi
https://read.qxmd.com/read/38545324/impact-of-implantation-depth-and-calcium-burden-on-infranodal-conduction-delay-after-transcatheter-aortic-valve-replacement
#11
JOURNAL ARTICLE
Andrea Papa, Teodor Serban, Ivo Strebel, Sven Knecht, Corinne Isenegger, Thomas Nestelberger, Christoph Kaiser, Gregor Leibundgut, Philipp Haaf, Beat Schaer, Philipp Krisai, Stefan Osswald, Christian Sticherling, Michael Kühne, Patrick Badertscher
BACKGROUND: Infranodal conduction disorders are common after transcatheter aortic valve replacement (TAVR). Risk factors are incompletely understood. OBJECTIVE: The purpose of this study was to assess the impact of valve implantation depth and calcium burden of the device landing zone on infranodal conduction intraprocedure pre- and post-TAVR. METHODS: In all patients undergoing TAVR between June 2020 and June 2021, the His-ventricle (HV) interval was measured pre- and post-valve deployment...
February 2024: Heart rhythm O2
https://read.qxmd.com/read/38545321/characterizing-cardiac-contractile-motion-for-noninvasive-radioablation-of-ventricular-tachycardia
#12
JOURNAL ARTICLE
Bryan Wu, Todd Atwood, Arno J Mundt, Jennifer Karunamuni, Paul Stark, Albert Hsiao, Frederick Han, Jonathan C Hsu, Kurt Hoffmayer, Farshad Raissi, Ulrika Birgersdotter-Green, Gregory Feld, David E Krummen, Gordon Ho
BACKGROUND: Respiratory motion management strategies are used to minimize the effects of breathing on the precision of stereotactic ablative radiotherapy for ventricular tachycardia, but the extent of cardiac contractile motion of the human heart has not been systematically explored. OBJECTIVE: We aim to assess the magnitude of cardiac contractile motion between different directions and locations in the heart. METHODS: Patients with intracardiac leads or valves who underwent 4-dimensional cardiac computed tomography (CT) prior to a catheter ablation procedure for atrial or ventricular arrhythmias at 2 medical centers were studied retrospectively...
February 2024: Heart rhythm O2
https://read.qxmd.com/read/38544982/a-gmr-enzymatic-assay-for-quantifying-nuclease-and-peptidase-activity
#13
JOURNAL ARTICLE
Michael Sveiven, Ana K Serrano, Joshua Rosenberg, Douglas J Conrad, Drew A Hall, Anthony J O'Donoghue
Hydrolytic enzymes play crucial roles in cellular processes, and dysregulation of their activities is implicated in various physiological and pathological conditions. These enzymes cleave substrates such as peptide bonds, phosphodiester bonds, glycosidic bonds, and other esters. Detecting aberrant hydrolase activity is vital for understanding disease mechanisms and developing targeted therapeutic interventions. This study introduces a novel approach to measuring hydrolase activity using giant magnetoresistive (GMR) spin valve sensors...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38544674/assessment-and-diagnostic-methods-of-internal-nasal-valve-systematic-review-and-meta-analysis
#14
REVIEW
Abdulaziz AlEnazi, Almaha H Alshathri, Aljohara H Alshathri, Aljoud Algazlan, Nuha Alkudsi, Hassan Assiri, Ahmed Alarfaj
BACKGROUND: Accurate methods are needed to evaluate the anatomy of the internal nasal valve (INV), yet there is currently no ideal measurement technique. Our systematic review aims to establish a comprehensive INV assessment tool, compare different INV diagnostic tools, and establish the most ideal measurement technique for the evaluation of the INV. METHODS: A systematic review and meta-analysis were conducted following the PRISMA guidelines, and the study was recorded in PROSPERO under reference number CRD42023407950...
June 2024: JPRAS Open
https://read.qxmd.com/read/38544627/unusual-presentation-of-corynebacterium-endocarditis-in-a-patient-without-conventional-risk-factors-a-case-report
#15
Abbas Mohammadi, Dima Youssef, Ashkan Mohammadi
Infective endocarditis (IE) is a widespread condition marked by the infection of native or prosthetic heart valves, the endocardial surface, or an indwelling cardiac device. While native-valve IE is uncommon, patients with IE represent a diverse spectrum. Some respond well to treatment with few complications, while others face severe complications and an increased risk of mortality. Various factors contribute to this outcome, including delayed diagnosis, underlying health conditions like immunocompromised status or chronic diseases, and intravenous drug use...
February 2024: Curēus
https://read.qxmd.com/read/38544298/technical-considerations-and-sizing-of-external-annuloplasty-in-the-ross-procedure
#16
JOURNAL ARTICLE
Andrej Myjavec, Jan Gofus, Pavel Zacek, Martin Vobornik, Youssef Shahin, Jan Vojacek
Pure aortic regurgitation and dilation of aortic annulus are the most significant risk factors for the failure of pulmonary autograft after the Ross procedure. Aortic annuloplasty has a positive effect on the durability of the autograft. Previously we described a technique for external annuloplasty with dedicated Coroneo ring (Coroneo, Extra-Aortic, Montreal, QC, Canada). In the present manuscript we suggest the sizing of annuloplasty based on the diameter of pulmonary autograft annulus.
March 27, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38544088/performance-assessment-of-pneumatic-driven-automatic-valves-to-improve-pipeline-fault-detection-procedure-by-fast-transient-tests
#17
JOURNAL ARTICLE
Francesco Castellani, Caterina Capponi, Bruno Brunone, Matteo Vedovelli, Silvia Meniconi
The use of fast transients for fault detection in long transmission networks makes the generation of controlled transients crucial. In order to maximise the information that can be extracted from the measured pressure time history (pressure signal), the transients must meet certain requirements. In particular, the manoeuvre that generates the transient must be fast and repeatable, and must produce a pressure wave that is as sharp as possible, without spurious pressure oscillations. This implies the use of small-diameter valves and often pneumatically operated automatic valves...
March 12, 2024: Sensors
https://read.qxmd.com/read/38544078/deep-learning-based-prognostics-and-health-management-model-for-pilot-operated-cryogenic-safety-valves
#18
JOURNAL ARTICLE
Minho Kim, Hansaem Seong, Dohyun Kim
This paper highlights the significance of safety and reliability in modern industries, particularly in sectors like petroleum and LNG, where safety valves play a critical role in ensuring system safety under extreme conditions. To enhance the reliability of these valves, this study aims to develop a deep learning-based prognostics and health management (PHM) model. Past empirical methods have limitations, driving the need for data-driven prediction models. The proposed model monitors safety valve performance, detects anomalies in real time, and prevents accidents caused by system failures...
March 12, 2024: Sensors
https://read.qxmd.com/read/38543617/vancomycin-resistant-streptococcus-thoraltensis-a-case-report-of-bacterial-endocarditis-and-review-of-literature-on-infections-caused-by-this-pathogen
#19
REVIEW
Roxana Mihaela Chiorescu, Sandor Botond Buksa, Alexandru Botan, Mihaela Mocan, Carmen Costache, Dan Alexandru Toc
Streptococcus thoraltensis is a rare species, part of the viridans streptococcus group, found initially in rabbits and pigs, which can be vancomycin-resistant. We present the case of a 65-year-old patient, a smoker and chronic alcohol consumer with chronic obstructive pulmonary disease (COPD) and multiple dental foci who had been diagnosed with bacterial endocarditis caused by Streptococcus thoraltensis . The particular elements of the case consisted of an atypical clinical presentation with diarrheal stools, abdominal pain, concomitant damage to the aortic and tricuspid valves, the presence of large vegetations (>2 cm), and a vancomycin-resistant strain of Streptococcus thoraltensis ...
March 12, 2024: Microorganisms
https://read.qxmd.com/read/38543396/study-on-the-low-velocity-impact-response-and-damage-mechanisms-of-thermoplastic-composites
#20
JOURNAL ARTICLE
Liu Han, Hui Qi, Jinshui Yang, Fuqing Chu, Changliang Lin, Pingan Liu, Qian Zhang
A comparative experimental and numerical study of the impact behaviour of carbon-fiber-reinforced thermoplastic (TP) and thermoset (TS) composites has been carried out. On the one hand, low velocity impact (LVI) tests were performed on TP and TS composites with different lay-up sequences at different energy levels, and the damage modes and microscopic damage mechanisms after impact were investigated using macroscale inspection, C-scan inspection, and X-ray-computed tomography. The comparative results show that the initial damage valve force under LVI depends not only on the material, but also on the layup sequence...
March 13, 2024: Polymers
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