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https://www.readbyqxmd.com/read/29230407/comparison-of-the-effect-of-low-frequency-repetitive-transcranial-magnetic-stimulation-with-that-of-theta-burst-stimulation-on-upper-limb-motor-function-in-poststroke-patients
#1
Takahiro Kondo, Naoki Yamada, Ryo Momosaki, Masato Shimizu, Masahiro Abo
Background: The purpose of this study was to evaluate the difference between the therapeutic effect of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) and that of continuous theta burst stimulation (cTBS), when each is combined with intensive occupational therapy (OT), in poststroke patients with upper limb hemiparesis. Materials and Methods: The study subjects were 103 poststroke patients with upper limb hemiparesis, who were divided into two groups: the LF-rTMS group (n = 71) and the cTBS group (three pulse bursts at 50 Hz) (n = 32)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29228358/theta-resting-eeg-in-tpj-psts-is-associated-with-individual-differences-in-the-feeling-of-being-looked-at
#2
Lorena R R Gianotti, Janek S Lobmaier, Cinzia Calluso, Franziska M Dahinden, Daria Knoch
Direct eye gaze is a powerful stimulus in social interactions, yet people vary considerably in the range of gaze lines that they accept as being direct (cone of direct gaze, CoDG). Here, we searched for a possible neural trait marker of these individual differences. We measured the width of the CoDG in 137 healthy participants and related their individual CoDG to their neural baseline activation as measured with resting electroencephalogram (EEG). Using a source-localization technique, we found that resting theta current density in the left temporo-parietal junction (TPJ) and adjacent posterior superior temporal sulcus (pSTS) was associated with the width of CoDG...
December 7, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29226035/molecular-evolution-of-virulence-genes-and-non-virulence-genes-in-clinical-natural-and-artificial-environmental-legionella-pneumophila-isolates
#3
Xiao-Yong Zhan, Qing-Yi Zhu
Background: L. pneumophila is the main causative agent of Legionnaires' disease. Free-living amoeba in natural aquatic environments is the reservoir and shelter for L. pneumophila. From natural water sources, L. pneumophila can colonize artificial environments such as cooling towers and hot-water systems, and then spread in aerosols, infecting the susceptible person. Therefore, molecular phylogeny and genetic variability of L. pneumophila from different sources (natural water, artificial water, and human lung tissue) might be distinct because of the selection pressure in different environments...
2017: PeerJ
https://www.readbyqxmd.com/read/29225550/theta-is-the-new-alpha
#4
COMMENT
Libor Velíšek
No abstract text is available yet for this article.
September 2017: Epilepsy Currents
https://www.readbyqxmd.com/read/29224411/change-in-quantitative-eeg-theta-cordance-as-a-potential-predictor-of-repetitive-transcranial-magnetic-stimulation-clinical-outcome-in-major-depressive-disorder
#5
Aimee M Hunter, Thien X Nghiem, Ian A Cook, David E Krantz, Michael J Minzenberg, Andrew F Leuchter
Repetitive transcranial magnetic stimulation (rTMS) has demonstrated efficacy in major depressive disorder (MDD), although clinical outcome is variable. Change in the resting-state quantitative electroencephalogram (qEEG), particularly in theta cordance early in the course of treatment, has been linked to antidepressant medication outcomes but has not been examined extensively in clinical rTMS. This study examined change in theta cordance over the first week of clinical rTMS and sought to identify a biomarker that would predict outcome at the end of 6 weeks of treatment...
November 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29224040/treatment-of-auditory-hallucinations-with-bilateral-theta-burst-stimulation-ctbs-protocol-of-a-randomized-double-blind-placebo-controlled-multicenter-trial
#6
Christian Plewnia, Bettina Brendel, Tobias Schwippel, Peter Martus, Joachim Cordes, Alkomiet Hasan, Andreas J Fallgatter
Auditory verbal hallucinations (AH) are core symptoms of schizophrenia. They are often severely distressing and refractory to therapy. Their perception is associated with increased activity in temporoparietal areas of the brain. Repetitive transcranial magnetic stimulation (rTMS) can reduce focal brain hyperactivity and has been shown to ameliorate AH. However, controlled multicenter clinical trials are still missing, effect sizes are moderate, and the treatment with rTMS is time consuming. Continuous theta burst stimulation (cTBS) is a quicker and potentially more effective technique to reduce cortical hyperactivity...
December 9, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29223708/comparison-of-neuroplastic-responses-to-cathodal-transcranial-direct-current-stimulation-and-continuous-theta-burst-stimulation-in-subacute-stroke
#7
Pierre Nicolo, Cécile Magnin, Elena Pedrazzini, Gijs Plomp, Anaïs Mottaz, Armin Schnider, Adrian G Guggisberg
OBJECTIVE: To investigate the effects of cathodal transcranial direct current stimulation (tDCS) and continuous theta burst stimulation (cTBS) on neural network connectivity and motor recovery in individuals with subacute stroke. DESIGN: Double-blinded, randomized, placebo-controlled study. SETTING: Stroke subjects recruited through a university hospital rehabilitation program. PARTICIPANTS: Stroke inpatients (N=41; mean age 65y, range 28-85; mean weeks poststroke 5, range 2-10) with resultant paresis in the upper extremity (mean Fugl-Meyer score 14, range 3-48)...
December 6, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29222722/binaural-auditory-beats-affect-long-term-memory
#8
Miguel Garcia-Argibay, Miguel A Santed, José M Reales
The presentation of two pure tones to each ear separately with a slight difference in their frequency results in the perception of a single tone that fluctuates in amplitude at a frequency that equals the difference of interaural frequencies. This perceptual phenomenon is known as binaural auditory beats, and it is thought to entrain electrocortical activity and enhance cognition functions such as attention and memory. The aim of this study was to determine the effect of binaural auditory beats on long-term memory...
December 8, 2017: Psychological Research
https://www.readbyqxmd.com/read/29221831/processing-of-implicit-versus-explicit-predictive-contextual-information-in-parkinson-s-disease
#9
Ling Li, Pablo Diaz-Brage, Helena Fernandez-Lago, Noa Fogelson
We investigated the effects of implicit versus explicit local contextual processing in Parkinson's disease (PD) using electrophysiological measures. EEG recording blocks consisted of targets preceded by either randomized sequences of standards or by sequences including a predictive sequence signaling the occurrence of a target event. PD patients ("on" medication) and healthy controls performed two sessions: in the first the regularity of the predictive sequence was implicit, while in the second this regularity was made explicit...
December 5, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29221792/the-serotonin-hallucinogen-5-meo-dmt-alters-cortico-thalamic-activity-in-freely-moving-mice-regionally-selective-involvement-of-5-ht1a-and-5-ht2a-receptors
#10
REVIEW
Maurizio S Riga, Laia Lladó-Pelfort, Francesc Artigas, Pau Celada
5-MeO-DMT is a natural hallucinogen acting as serotonin 5-HT1A/5-HT2A receptor agonist. Its ability to evoke hallucinations could be used to study the neurobiology of psychotic symptoms and to identify new treatment targets. Moreover, recent studies revealed the therapeutic potential of serotonin hallucinogens in treating mood and anxiety disorders. Our previous results in anesthetized animals show that 5-MeO-DMT alters cortical activity via 5-HT1A and 5-HT2A receptors. Here, we examined 5-MeO-DMT effects on oscillatory activity in prefrontal (PFC) and visual (V1) cortices, and in mediodorsal thalamus (MD) of freely-moving wild-type (WT) and 5-HT2A-R knockout (KO2A) mice...
December 5, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29219328/determination-of-hydrogen-density-by-swift-heavy-ions
#11
Ge Xu, M D Barriga-Carrasco, A Blazevic, B Borovkov, D Casas, K Cistakov, R Gavrilin, M Iberler, J Jacoby, G Loisch, R Morales, R Mäder, S-X Qin, T Rienecker, O Rosmej, S Savin, A Schönlein, K Weyrich, J Wiechula, J Wieser, G Q Xiao, Y T Zhao
A novel method to determine the total hydrogen density and, accordingly, a precise plasma temperature in a lowly ionized hydrogen plasma is described. The key to the method is to analyze the energy loss of swift heavy ions interacting with the respective bound and free electrons of the plasma. A slowly developing and lowly ionized hydrogen theta-pinch plasma is prepared. A Boltzmann plot of the hydrogen Balmer series and the Stark broadening of the H_{β} line preliminarily defines the plasma with a free electron density of (1...
November 17, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29218863/population-structure-and-migration-of-the-tobacco-blue-mold-pathogen-peronospora-tabacina-into-north-america-and-europe
#12
Monica Blanco-Meneses, Ignazio Carbone, Jean B Ristaino
Tobacco blue mold, caused by Peronospora tabacina, is an oomycete plant pathogen that causes yearly epidemics in tobacco (Nicotiana tabacum) in the U.S. and Europe. The genetic structure of P. tabacina was examined in order to understand genetic diversity, population structure and patterns of migration. Two nuclear loci, Igs2 and Ypt1 and one mitochondrial locus, cox2, were amplified, cloned and sequenced from fifty four isolates of P. tabacina from the U.S., Central America-Caribbean-Mexico (CCAM), Europe and the Middle East (EULE)...
December 8, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/29218075/il-32%C3%AE-a-recently-identified-anti-inflammatory-variant-of-il-32-and-its-preventive-role-in-various-disorders-and-tumor-suppressor-activity
#13
REVIEW
Muhammad Babar Khawar, Maryam Mukhtar, Muddasir Hassan Abbasi, Nadeem Sheikh
Interleukin-32 theta (IL-32θ) is newly identified isoform of IL-32 which plays a vital role in inflammatory responses. Like IL-32α and IL-32β, IL-32θ isoform acts as an intracellular inflammatory modulator. It results in reduction of IL-1β production by attenuating the expression of PU.1 and inhibition of monocytes differentiation into macrophages. IL-32θ hinders TNF-α expression by inhibiting p38 MAPK and inhibitor of κB (IκB) as well. It also reserved STAT3-ZEB1 pathway leading to the inhibition of epithelial-mesenchymal transition (EMT) and stemness...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29218004/decoding-of-self-paced-lower-limb-movement-intention-a-case-study-on-the-influence-factors
#14
Dong Liu, Weihai Chen, Ricardo Chavarriaga, Zhongcai Pei, José Del R Millán
Brain-machine interfaces (BMIs) have been applied as new rehabilitation tools for motor disabled individuals. Active involvement of cerebral activity has been shown to enhance neuroplasticity and thus to restore mobility. Various studies have focused on the detection of upper-limb movement intention, while the fewer study has investigated the lower-limb movement intention decoding. This study presents a BMI to decode the self-paced lower-limb movement intention, with 10 healthy subjects participating in the experiment...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29217994/local-fields-in-human-subthalamic-nucleus-track-the-lead-up-to-impulsive-choices
#15
John M Pearson, Patrick T Hickey, Shivanand P Lad, Michael L Platt, Dennis A Turner
The ability to adaptively minimize not only motor but cognitive symptoms of neurological diseases, such as Parkinson's Disease (PD) and obsessive-compulsive disorder (OCD), is a primary goal of next-generation deep brain stimulation (DBS) devices. On the basis of studies demonstrating a link between beta-band synchronization and severity of motor symptoms in PD, the minimization of beta band activity has been proposed as a potential training target for closed-loop DBS. At present, no comparable signal is known for the impulsive side effects of PD, though multiple studies have implicated theta band activity within the subthalamic nucleus (STN), the site of DBS treatment, in processes of conflict monitoring and countermanding...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29217685/scale-free-amplitude-modulation-of-neuronal-oscillations-tracks-comprehension-of-accelerated-speech
#16
Ana Filipa Teixeira Borges, Anne-Lise Giraud, Huibert D Mansvelder, Klaus Linkenkaer-Hansen
Speech comprehension is preserved up to a three-fold acceleration but rapidly deteriorates at higher speeds. Current models posit that perceptual resilience to accelerated speech is limited by the brain's ability to parse speech into syllabic units using delta/theta oscillations. Here, we ask whether the involvement of neuronal oscillations in processing accelerated speech also relates to their scale-free amplitude modulation as indexed by the strength of long-range temporal correlations (LRTC). We recorded magnetoencephalography (MEG) while 24 human subjects (12 females) listened to radio news uttered at different comprehensible rates, at a mostly unintelligible rate, and at this same speed interleaved with silence gaps...
December 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29216195/reduced-visual-attention-in-heterogeneous-textures-is-reflected-in-occipital-alpha-and-theta-band-activity
#17
Tobias Feldmann-Wüstefeld, Makoto Miyakoshi, Marco Alessandro Petilli, Anna Schubö, Scott Makeig
Increasing context heterogeneity has been found to reduce attention deployment towards an embedded target item. Heterogeneity in visual search tasks is typically induced by segmenting the background into several perceptual groups. In the present study, however, context heterogeneity was induced by varying whole-field heterogeneity, i.e., the degree of distractor variability within the entire context. This allowed us to (i) more gradually vary context heterogeneity, and (ii) investigate attention deployment on a whole-field scale...
2017: PloS One
https://www.readbyqxmd.com/read/29215577/acute-encephalitis-in-an-adult-with-diffuse-large-b-cell-lymphoma-with-secondary-involvement-of-the-central-nervous-system-infectious-or-non-infectious-etiology
#18
Surinder S Moonga, Kenneth Liang, Burke A Cunha
Both infectious and non-infectious etiologies of acute encephalitis have been described, as well as their specific presentations, diagnostic tests, and therapies. Classic findings of acute encephalitis include altered mental status, fever, and new lesions on neuroimaging or electroencephalogram (EEG). We report an interesting case of a 61-year-old male with a history of diffuse large B-cell lymphoma with secondary involvement of the central nervous system (SCNS-DLBCL). He presented with acute encephalitis: altered mental status, fever, leukocytosis, neuropsychiatric symptoms, multiple unchanged brain lesions on computed tomography scan of the head, and EEG showed mild to moderate diffuse slowing with low-moderate polymorphic delta and theta activity...
December 7, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29214156/off-target-effects-of-drugs-that-disrupt-human-mitochondrial-dna-maintenance
#19
REVIEW
Matthew J Young
Nucleoside reverse transcriptase inhibitors (NRTIs) were the first drugs used to treat human immunodeficiency virus (HIV) the cause of acquired immunodeficiency syndrome. Development of severe mitochondrial toxicity has been well documented in patients infected with HIV and administered NRTIs. In vitro biochemical experiments have demonstrated that the replicative mitochondrial DNA (mtDNA) polymerase gamma, Polg, is a sensitive target for inhibition by metabolically active forms of NRTIs, nucleotide reverse transcriptase inhibitors (NtRTIs)...
2017: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/29213509/comparative-analysis-of-the-electroencephalogram-in-patients-with-alzheimer-s-disease-diffuse-axonal-injury-patients-and-healthy-controls-using-loreta-analysis
#20
Jéssica Natuline Ianof, Francisco José Fraga, Leonardo Alves Ferreira, Renato Teodoro Ramos, José Luiz Carlos Demario, Regina Baratho, Luís Fernando Hindi Basile, Ricardo Nitrini, Renato Anghinah
Alzheimer's disease (AD) is a dementia that affects a large contingent of the elderly population characterized by the presence of neurofibrillary tangles and senile plaques. Traumatic brain injury (TBI) is a non-degenerative injury caused by an external mechanical force. One of the main causes of TBI is diffuse axonal injury (DAI), promoted by acceleration-deceleration mechanisms. Objective: To understand the electroencephalographic differences in functional mechanisms between AD and DAI groups...
April 2017: Dementia & Neuropsychologia
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