keyword
MENU ▼
Read by QxMD icon Read
search

Esophageal carcinoma

keyword
https://www.readbyqxmd.com/read/29223386/extensive-esophageal-papillomatosis-after-chemoradiotherapy-for-squamous-cell-carcinoma
#1
Wilson Siu, Graeme I Murray, Alastair McKinlay, Perminder Phull
No abstract text is available yet for this article.
December 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29223109/genome-wide-analysis-of-barrett-s-adenocarcinoma-a-first-step-towards-identifying-patients-at-risk-and-developing-therapeutic-paths
#2
Yiyang Dai, Qing Wang, Adrian Gonzalez Lopez, Mario Anders, Peter Malfertheiner, Michael Vieth, Wolfgang Kemmner
BACKGROUND: Barrett's esophagus metaplasia is the key precursor lesion of esophageal adenocarcinoma. The aim of this study was to find a subset of markers that may allow the identification of patients at risk for esophageal adenocarcinoma, and to determine genes differentially expressed in esophageal squamous cell carcinoma. METHODS: Laser capture microdissection technique was applied to procure cells from defined regions. Genome-wide RNA profiling was performed on esophageal adenocarcinoma (n = 21), Barrett's esophagus (n = 20), esophageal squamous carcinoma (n = 9) and healthy esophageal biopsies (n = 18) using the Affymetrix Human Genome U133plus 2...
December 6, 2017: Translational Oncology
https://www.readbyqxmd.com/read/29222587/gastrointestinal-manifestation-of-immunoglobulin-g4-related-disease-clarification-through-a-multicenter-survey
#3
Kenji Notohara, Terumi Kamisawa, Kazushige Uchida, Yoh Zen, Mitsuhiro Kawano, Satomi Kasashima, Yasuharu Sato, Masahiro Shiokawa, Takeshi Uehara, Hajime Yoshifuji, Hiroko Hayashi, Koichi Inoue, Keisuke Iwasaki, Hiroo Kawano, Hiroyuki Matsubayashi, Yukitoshi Moritani, Katsuhiko Murakawa, Yoshio Oka, Masatoshi Tateno, Kazuichi Okazaki, Tsutomu Chiba
BACKGROUND: Several reports on immunoglobulin (Ig)G4-related disease (IgG4-RD) with gastrointestinal involvement (IgG4-related gastrointestinal disease; IgG4-GID) have been published, although this entity has not been fully established clinicopathologically. Thus, we carried out a multicenter survey. METHODS: Patients with possible IgG4-GID who underwent resection were collected. Histologic slides were reevaluated, and eight cases with diffuse lymphoplasmacytic infiltration but without numerous neutrophils, granulations or epithelioid granulomas were further analyzed...
December 8, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29222520/smoking-and-alcohol-drinking-in-relation-to-the-risk-of-esophageal-squamous-cell-carcinoma-a-population-based-case-control-study-in-china
#4
Xiaorong Yang, Xingdong Chen, Maoqiang Zhuang, Ziyu Yuan, Shuping Nie, Ming Lu, Li Jin, Weimin Ye
Previous results regarding the associations between esophageal squamous-cell carcinoma (ESCC) risk and smoking/alcohol drinking in high-risk areas are inconsistent. We performed a large population-based case-control study from 2010 to 2013 in a high-incidence area of China, and enrolled 1353 ESCC cases and 1961 controls. Data regarding smoking and alcohol drinking were collected via face-to-face interviews using a structured questionnaire. Odd ratios (ORs) with 95% confidence intervals (CIs) were estimated using unconditional logistic regression models...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29221296/prognostic-role-of-initial-pan-endoscopic-tumor-length-at-diagnosis-in-operable-esophageal-squamous-cell-carcinoma-undergoing-esophagectomy-with-or-without-neoadjuvant-concurrent-chemoradiotherapy
#5
Chen-Sung Lin, Chao-Yu Liu, Chih-Tao Cheng, Yu-Chen Tsai, Lun-Wei Chiou, Ming-Yuan Lee, Chia-Chuan Liu, Chih-Hsun Shih
Background: The objective of this study was to appraise the prognostic role of initial pan-endoscopic tumor length at diagnosis within or between operable esophageal squamous cell carcinoma (ESCC) undergoing upfront esophagectomy or neoadjuvant concurrent chemoradiotherapy (nCCRT) followed by esophagectomy. Methods: Between Jan 2001 and Dec 2013 in Koo-Foundation Sun Yat-sen Cancer Center in Taiwan, 101 ESCC patients who underwent upfront esophagectomy (surgery group) and 128 nCCRT followed by esophagectomy (nCCRT-surgery group) were retrospectively collected...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221284/comparison-of-perioperative-outcomes-following-hybrid-minimally-invasive-versus-open-ivor-lewis-esophagectomy-for-esophageal-cancer
#6
Ju Sik Yun, Kook Joo Na, Sang Yun Song, Seok Kim, In Seok Jeong, Sang Gi Oh
Background: The outcomes of various minimally invasive esophagectomy (MIE) procedures for esophageal cancer have been reported; however, those of the hybrid approach are lacking. This study aimed to assess the impacts of hybrid minimally invasive Ivor Lewis esophagectomy (HIL, laparoscopy and right thoracotomy) for esophageal cancer on perioperative outcomes compared with the open approach. Methods: This was a retrospective study of 153 patients who underwent Ivor Lewis esophagectomy for squamous cell carcinoma between January 2008 and December 2016...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221271/minimally-invasive-esophagectomy-is-a-safe-surgical-treatment-for-locally-advanced-pathologic-t3-esophageal-squamous-cell-carcinoma
#7
Xiaobin Zhang, Yu Yang, Bo Ye, Yifeng Sun, Xufeng Guo, Rong Hua, Teng Mao, Wentao Fang, Zhigang Li
Background: Previous studies have shown that minimally invasive esophagectomy (MIE) is safe and feasible. However, several of these studies had selection bias because they included more patients with early-stage cancer, and no study has compared the outcomes of locally advanced pathologic T3 (pT3) esophageal carcinoma between MIE and open surgery. Methods: This retrospective analysis included 229 patients with stage pT3 esophageal squamous cell carcinoma (ESCC) who underwent esophagectomy from January 2013 to June 2015...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221250/should-ct2n0m0-be-managed-as-a-localized-or-locally-advanced-esophageal-carcinoma
#8
EDITORIAL
Nicola Fazio, Emilio Bertani, Chiara Alessandra Cella
No abstract text is available yet for this article.
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221198/the-prognostic-significance-of-celiac-lymph-node-metastasis-in-patients-with-locally-advanced-esophageal-squamous-cell-carcinoma-receiving-curative-concurrent-chemoradiotherapy
#9
Yen-Hao Chen, Hung-I Lu, Yu-Ming Wang, Chien-Ming Lo, Shang-Yu Chou, Cheng-Hua Huang, Li-Hsueh Shih, Su-Wei Chen, Shau-Hsuan Li
Background: To evaluate the clinical outcomes of celiac lymph node (LN) metastasis in patients with locally advanced esophageal squamous cell carcinoma (ESCC) receiving curative concurrent chemoradiotherapy (CCRT). Materials and Methods: A total of 375 stage III ESCC patients were identified, including 51 patients with celiac LN metastasis and 324 patients without celiac LN metastasis. Among these 324 patients without celiac LN metastasis, 51 were matched with the 51 patients with celiac LN metastasis using the propensity score matching method...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29221176/alpha-tocopherol-prevents-esophageal-squamous-cell-carcinoma-by-modulating-ppar%C3%AE-akt-signaling-pathway-at-the-early-stage-of-carcinogenesis
#10
Miao Xu, Hui Yang, Qiannan Zhang, Ping Lu, Yongquan Feng, Xue Geng, Lishi Zhang, Xudong Jia
The poor prognosis of esophageal squamous cell carcinoma (ESCC) emphasizes the urgent need to better understand the carcinogenesis and develop prevention strategies. Previous studies have highlighted the potential of using Vitamin E (tocopherols) for cancer chemoprevention, but the preventive activity of α-Tocopherol against ESCC remains to be elucidated. Our data showed that early-stage supplementation with α-Tocopherol significantly prevented esophageal carcinogenesis induced by N-nitrosomethylbenzylamine (NMBA) in ESCC rat model...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29218248/propafenone-suppresses-esophageal-cancer-proliferation-through-inducing-mitochondrial-dysfunction
#11
Wei-Bin Zheng, Yang-Jia Li, Yang Wang, Jie Yang, Can-Can Zheng, Xiao-Hui Huang, Bin Li, Qing-Yu He
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors with poor survival and limited therapeutic options. The aim of this study is to identify novel anticancer strategies from existing Food and Drug Administration (FDA)-approved drugs that have been used to clinically treat other diseases. Here, propafenone, an antiarrhythmic medication, was found to induce apoptosis and exert a significantly inhibitory effect on the proliferation and colony-forming ability of ESCC cells in a dose-dependent manner without observed cytotoxicity on normal esophageal epithelial cells...
2017: American Journal of Cancer Research
https://www.readbyqxmd.com/read/29218243/elevated-hbxip-expression-is-associated-with-aggressive-phenotype-and-poor-prognosis-in-esophageal-squamous-cell-carcinoma
#12
Honggang Xia, Lan Ma, Jing Li, Hongyu Bai, Dongbin Wang
The oncoprotein hepatitis B virus X-interacting protein (HBXIP) has been suggested to play an essential role in several malignancies. However, the clinicopathological significance and prognostic value of HBXIP expression in esophageal squamous cell carcinoma (ESCC) is still unknown. Therefore the aim of this study was to characterize HBXIP expression and its prognostic value in ESCC. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot were performed to assess the mRNA and protein expression of HBXIP in ESCC tissues and cell lines...
2017: American Journal of Cancer Research
https://www.readbyqxmd.com/read/29218114/comparative-transcriptome-analysis-of-the-global-circular-rnas-expression-profiles-between-shee-and-sheec-cell-lines
#13
Jiachun Sun, Xiaozhi Yuan, Xiangming Li, Dengkui Wang, Tanyou Shan, Wei Wang, Qiuyan Wan, Xinshuai Wang, Junqiang Yan, Shegan Gao
Esophageal squamous cell carcinoma (ESCC) is widely regarded as one of the most lethal types of cancer around the world. The fact that early detection of ESCC could dramatically improve the treatment outcome of the patients has sparked considerable interest in searching for reliable and accurate diagnostic biomarkers. Recently, circular RNAs (circRNA) have emerged as a new type of non-coding RNAs with significant RNase resistance, wide abundance and remarkable internal diversity. There is also increasing evidence suggesting that circRNAs could be implicated in the pathogenesis of cancer and other diseases...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29218108/the-synergistic-effect-of-esophageal-squamous-cell-carcinoma-kyse150-cells-and-m2-macrophages-on-lymphatic-endothelial-cells
#14
Miao-Miao Sun, Lu-Lu He, Hong-Xin Zhang, Na Wei, Wei-Wei Wang, Guo-Zhong Jiang, Zheng-Yang Wang, Dong-Mei Zhao, Kui-Sheng Chen
Objective: This study aimed to investigate whether tumor-associated macrophages (TAMs) and esophageal squamous cell carcinoma (ESCC) cells could synergistically influence the generation of lymphatic vessels via the VEGF-C/VEGFR-3 signaling pathway and to address its mechanism. Methods: M2 macrophages were sorted with immunomagnetic beads and induced in vitro. VEGF-C siRNA plasmids were constructed and transfected into M2 macrophages and the ESCC cell line KYSE150. Different conditioned culture media before and after transfection were collected and classified into different groups for culturing ESCC-associated lymphatic endothelial cells (ESCC-LECs)...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29216866/cross-sectional-study-of-serum-selenium-concentration-and-esophageal-squamous-dysplasia-in-western-kenya
#15
Natalie R Pritchett, Stephen L Burgert, Gwen A Murphy, John D Brockman, Russell E White, Justus Lando, Robert Chepkwony, Mark D Topazian, Christian C Abnet, Sanford M Dawsey, Michael M Mwachiro
BACKGROUND: Low serum selenium status has been associated with increased risk of esophageal squamous cell carcinoma (ESCC). East Africa is a region of high ESCC incidence and is known to have low soil selenium levels, but this association has not previously been evaluated. In this study we assessed the association of serum selenium concentration and the prevalence of esophageal squamous dysplasia (ESD), the precursor lesion of ESCC, in a cross-sectional study of subjects from Bomet, Kenya...
December 8, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29216832/a-long-surviving-patient-with-advanced-esophageal-basaloid-squamous-cell-carcinoma-treated-only-with-radiotherapy-case-report-and-literature-review
#16
Toshiya Maebayashi, Naoya Ishibashi, Takuya Aizawa, Masakuni Sakaguchi, Homma Taku, Moritaka Ohhara, Toshirou Takimoto, Yoshiaki Tanaka
BACKGROUND: Esophageal basaloid squamous cell carcinoma (EBSCC) is a rare malignant disease. Advanced EBSCC (AEBSCC) has a poorer prognosis than the more common esophageal squamous cell carcinoma, but no treatment policy has yet been established. This is the first reported case with AEBSCC treated only with radiotherapy. Thus, our long-surviving patient merits consideration. We therefore reviewed cases with the same stage of AEBSCC for further investigation. CASE PRESENTATION: An 85-year-old man with a chief complaint of difficulty swallowing foods was diagnosed with AEBSCC, cT3N1M0, stage III, by thorough examination...
December 8, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29216641/znf750-expression-is-a-potential-prognostic-biomarker-in-esophageal-squamous-cell-carcinoma
#17
Ryota Otsuka, Yasunori Akutsu, Haruhito Sakata, Naoyuki Hanari, Kentaro Murakami, Masayuki Kano, Takeshi Toyozumi, Masahiko Takahashi, Yasunori Matsumoto, Nobufumi Sekino, Masaya Yokoyama, Koichiro Okada, Tadashi Shiraishi, Aki Komatsu, Keiko Iida, Hisahiro Matsubara
OBJECTIVE: ZNF750, a transcriptional regulator of epidermal differentiation, has been identified as a tumor suppressor in esophageal squamous cell carcinoma (ESCC). The aim of the present study was to investigate the clinical and prognostic significance of ZNF750 expression and to evaluate the effect of ZNF750 knockdown on cell proliferation, migration, and invasion in ESCC. METHODS: A total of 124 patients with ESCC who underwent curative esophagectomy were evaluated in this study...
December 8, 2017: Oncology
https://www.readbyqxmd.com/read/29215312/gstm1-and-gstt1-gene-polymorphisms-gene-gene-interaction-and-esophageal-carcinoma-risk-evidence-from-an-updated-meta-analysis
#18
Liping Ma, Biyang Lan, Lingxiao Guo, Shaoyun Nong, Cuibo Huang, Qiulong Wu, Zhihu Huang
BACKGROUND: Published data regarding the association between GSTM1 and/or GSTT1 gene polymorphisms and esophageal cancer (EC) susceptibility remain inconclusive. To clarify these associations, a meta-analysis was conducted. METHODS: We conducted a comprehensive search in PubMed, Embase, and the China National Knowledge Infrastructure (CNKI) for all such manuscripts published as of May 1, 2017. The pooled odds ratio (ORs) with confidence intervals (95% CI) were estimated for each study to assess the strength of the association...
December 7, 2017: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/29213217/increased-expression-of-march8-an-e3-ubiquitin-ligase-is-associated-with-growth-of-esophageal-tumor
#19
Shivam Singh, Anoop Saraya, Prasenjit Das, Rinu Sharma
Background: Herein, for the first time, we report aberrant expression of membrane-associated RING-CH8 (MARCH8) in human esophageal squamous cell carcinoma. MARCH8 is a member of the recently discovered MARCH family of really interesting new genes (RING) E3 ligases. Though initial studies primarily focused on its immunomodulatory role, the newly discovered targets of this E3 ligase point towards its possible role in other biological processes such as embryogenesis and inhibition of apoptosis...
2017: Cancer Cell International
https://www.readbyqxmd.com/read/29212180/padi4-rs2240337-g-a-polymorphism-is-associated-with-susceptibility-of-esophageal-squamous-cell-carcinoma-in-a-chinese-population
#20
Liming Wang, Haiyong Gu, Tao Long, Huiwen Pan, Lu Lv, Yijun Shi, Jingfeng Zhu, Yangyong Sun, Weifeng Tang, Guowen Ding, Suocheng Chen, Yu Fan, Hao Ding, Cheng Qian, Qun Wang, Jun Yao, Lijie Tan, Jun Yin
Background: Esophageal cancer (EC) remains one of the major causes of cancer incidence and mortality worldwide. Genetic factors, such as single nucleotide polymorphisms (SNPs), may contribute to the carcinogenesis of EC. Methods: We conducted a hospital based case-control study to evaluate the genetic susceptibility of SNPs on the development of EC. A total of 629 esophageal squamous cell carcinoma (ESCC) cases and 686 controls were enrolled for this study. Seven PADI4 SNPs were determined by ligation detection reaction method...
November 7, 2017: Oncotarget
keyword
keyword
14760
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"