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Retroperitoneal tumor

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https://www.readbyqxmd.com/read/28081195/assessment-of-volumetric-versus-manual-measurement-in-disseminated-testicular-cancer-no-difference-in-assessment-between-non-radiologists-and-genitourinary-radiologist
#1
Çiğdem Öztürk, Ton Velleman, Alphons H H Bongaerts, L M Bergman, Robert J van Ginkel, Jourik A Gietema, Harald J Hoekstra
BACKGROUND: The aim of this study was to assess the feasibility and reproducibility of semi-automatic volumetric measurement of retroperitoneal lymph node metastases in testicular cancer (TC) patients treated with chemotherapy versus the standardized manual measurements based on RECIST criteria. METHODS: 21 TC patients with retroperitoneal lymph node metastases of testicular cancer were studied with a CT scan of chest and abdomen before and after cisplatin based chemotherapy...
2017: PloS One
https://www.readbyqxmd.com/read/28074298/effect-of-intraoperative-radiotherapy-in-the-treatment-of-retroperitoneal-sarcoma
#2
Liz B Wang, David McAneny, Gerard Doherty, Teviah Sachs
BACKGROUND: Current National Comprehensive Cancer Network guidelines for the treatment of retroperitoneal sarcomas (RPS) endorse surgical resection, but the role of radiotherapy (RT) is less clear. We investigate the utilization and benefits of intraoperative RT (IORT) in the treatment of RPS. METHODS: We queried the Surveillance, Epidemiology and End Results (SEER) database (1988-2013) for the utilization of IORT and perioperative external beam RT (EBRT) in patients who underwent surgical resection of RPS...
January 10, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28063603/prostate-specific-membrane-antigen-targeted-ligand-positron-emission-tomography-computed-tomography-and-immunohistochemical-findings-in-a-patient-with-synchronous-metastatic-penile-and-prostate-cancer
#3
Michael Froehner, Friederike Kuithan, Klaus Zöphel, Ulrike Heberling, Michael Laniado, Manfred P Wirth
A 68-year-old man presented with synchronous metastatic penile and prostate cancer. 68Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) revealed tracer uptake in inguinal, pelvic, and retroperitoneal metastases. Lymph node biopsies and immunohistochemical staining revealed that both cancers involved the lymph nodes and expressed PSMA. In the deposits of penile squamous cell carcinoma, PSMA expression was seen in tumor vessels and may explain the PSMA-PET/CT positivity of inguinal nodes involved in squamous cell carcinoma...
January 4, 2017: Urology
https://www.readbyqxmd.com/read/28062895/3d-printed-renal-cancer-models-derived-from-mri-data-application-in-pre-surgical-planning
#4
Nicole Wake, Temitope Rude, Stella K Kang, Michael D Stifelman, James F Borin, Daniel K Sodickson, William C Huang, Hersh Chandarana
OBJECTIVE: To determine whether patient-specific 3D printed renal tumor models change pre-operative planning decisions made by urological surgeons in preparation for complex renal mass surgical procedures. MATERIALS AND METHODS: From our ongoing IRB approved study on renal neoplasms, ten renal mass cases were retrospectively selected based on Nephrometry Score greater than 5 (range 6-10). A 3D post-contrast fat-suppressed gradient-echo T1-weighted sequence was used to generate 3D printed models...
January 7, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28060250/murine-experimental-model-of-original-tumor-development-and-peritoneal-metastasis-via-orthotopic-inoculation-with-ovarian-carcinoma-cells
#5
Yoshihiro Koya, Hiroaki Kajiyama, Wenting Liu, Kiyosumi Shibata, Takeshi Senga, Fumitaka Kikkawa
Epithelial ovarian carcinoma (EOC) is associated with a poor prognosis because it shows peritoneal dissemination. To improve the prognosis, it is important to control peritoneal dissemination. However, it is still unclear how tumor cells detach from primary lesions and attach to the mesothelium. The establishment of an appropriate animal model is needed to gain an understanding of the mechanism of peritoneal dissemination in vivo. In the current study, we introduce the process from the local injection of EOC cells into the murine ovarian surface to the development of metastasis, including the peritoneum and distant organs...
December 9, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28048758/su-f-t-90-patterns-of-electron-iort-treatments-in-the-u-s-europe-and-asia
#6
S Adamczyk, D Goer, R Ash
PURPOSE: We analyzed data collected from worldwide centers active in electron IORT with a focus on the technical variables of the treatment. Particular attention was given to the dominant tumor sites. METHODS: 54 Mobetron users from 14 countries in clinical operation prior to December 31, 2014, were invited to participate in this study. 29 centers contributed to this survey in sufficient detail to be included in this report. 6,035 patients were treated since 1997...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28034669/pioglitazone-improves-insulin-sensitivity-and-reduces-weight-loss-in-walker-256-tumor-bearing-rats
#7
Flaviane de Fatima Silva, Milene Ortiz-Silva, Winny Beatriz de Souza Galia, Priscila Cassolla, Maria Fernanda Rodrigues Graciano, Cassia Thaïs Bussamra Vieira Zaia, Dimas Zaia, Ângelo Rafael Carpinelli, Francemilson Goulart da Silva, Helenir Medri de Souza
AIM: The lipogenic effect of pioglitazone (PGZ), an insulin (INS) sensitizer, is well established. However, few studies have evaluated PGZ effects in preventing weight loss in cancer. We investigated PGZ effects, alone or associated with INS, on INS resistance, cachexia and metabolic abnormalities induced by Walker-256 tumor in rats MAIN METHODS: PGZ (5.0mg·kg(-1), oral) or PGZ+INS (NPH, 1.0UI·kg(-1), sc), were once-daily administered during 12days, starting on the day inoculation of Walker-256 tumor cells...
December 26, 2016: Life Sciences
https://www.readbyqxmd.com/read/28031087/life-threatening-spontaneous-retroperitoneal-haemorrhage-role-of-multidetector-ct-angiography-for-the-emergency-management
#8
Zhi-Wei Wang, Hua-Dan Xue, Xiao-Guang Li, Jie Pan, Xiao-Bo Zhang, Zheng-Yu Jin
Objective To evaluate the role of multidetector computed tomography-angiography (MDCTA) for management of life-threatening spontaneous retroperitoneal haemorrhage (SRH).Methods A retrospective analysis of the medical records of all SRH patients admitted to our hospital from January 1, 2005 to November 31, 2014 was performed. SRH was defined as unrelated to invasive procedures, surgery, trauma, abdominal tumor or aortic aneurysm. Life-threatening SRH was defined as hemodynamic instability with hypotension. Sixteen cases met the inclusive criteria...
March 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28028944/a-comparison-of-two-approaches-to-laparoscopic-adrenalectomy-lateral-transperitoneal-versus-posterior-retroperitoneal-approach
#9
Magda Marek-Safiejko, Kamil Safiejko, Jerzy Łukaszewicz, Jacek Dadan, Robert J Ładny, Robert Kozłowski, Piotr Wojskowicz, Piotr Myśliwiec
BACKGROUND: Laparoscopic adrenalectomy is the gold standard for the surgical treatment of benign adrenal masses. It is most commonly performed using the lateral transperitoneal approach (LTA) and the posterior retroperitoneal approach (PRA). The choice of the method depends on contraindications for a particular approach in an individual case and surgical experience. The objective of the article is to compare two approaches, LTA and PRA, in view of our own experience and literature review...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28012782/epithelioid-hemangioendothelioma-presenting-as-inferior-vena-cava-obstruction-diagnosed-using-an-endovascular-thrombectomy-device
#10
Loay Kabbani, Praveen Balraj, Jeff Mathews, Francis Tinney, Scott Schwartz, David Kwon, Felix Braun, Sara Wasilenko
Epithelioid hemangioendothelioma is a rare vascular sarcoma that arises from the lining (intima) of blood vessels. We report a case of epithelioid hemangioendothelioma in a 43-year-old male patient, who presented with inferior vena cava obstruction and acute bilateral lower extremity deep vein thrombosis. Mechanical thrombectomy was performed with an endovascular thrombectomy device, followed by stent placement in the inferior vena cava. The initial pathology on the retrieved specimen revealed an undifferentiated neoplasm, and surgical resection of the retroperitoneal soft tissue tumor of the inferior vena cava documented a rare case of epithelioid hemangioendothelioma...
December 21, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28012446/retroperitoneal-liposarcoma-excreting-insulin-like-growth-factor-2-that-induced-severe-hypoglycemia
#11
Takuma Kato, Mikio Sugimoto, Motoki Yamashita, Yasuyuki Miyauchi, Hiromi Hirama, Hiroyuki Tsunemori, Nobufumi Ueda, Hitomi Imachi, Shinsuke Shibuya, Yoshio Kushida, Yoshiyuki Kakehi
Insulin-like growth factor 2 is overexpressed in various cancers, and is associated with a poor prognosis. Also, it is known that insulin-like growth factor 2 is an etiology of non-islet cell tumor hypoglycemia. In this report, we describe a case of unexpected hypoglycemia caused by a dedifferentiated liposarcoma producing insulin-like growth factor 2. A large mass in the retroperitoneum was detected in a 61-year-old man who complained of appetite loss. Despite having no history of diabetes mellitus, hypoglycemia suddenly occurred after admission, but oral glucose therapy was ineffective...
December 24, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28005154/-pathogenesis-of-urological-complications-after-radiation-therapy
#12
Y Tolkach, G Kristiansen
Radiation therapy is a treatment modality that is often used in the uro-oncological setting. The common indication for the radiation therapy in the urological sphere is prostate cancer, whether it is used primarily as a radical approach, or postoperatively as adjuvant or salvage therapy. All urological organs are sensitive to radiation injury with the urinary bladder being the most susceptible with a typical cascade including acute and late changes, arising in the dose-dependent manner. The common indication for radiation therapy in urology is prostate cancer, which collaterally affects the urinary bladder and rarely urethra (especially the bulbo-membranous urethra)...
December 22, 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28002522/primary-retroperitoneal-seminoma-embryology-histopathology-and-treatment-particularities
#13
Constantin Virgil Gîngu, Mihaela Mihai, Cătălin Baston, Mugurel Alexandru Crăsneanu, Alexandru Vladimir Dick, Vlad Olaru, Ioanel Sinescu
INTRODUCTION: Retroperitoneal seminoma is a very rare form of cancer, with embryological origin represented by primordial germ cells from the urogenital ridges left behind during the fetal development. Extragenital germ cell tumors can also occur in the mediastinum or the pineal gland. The aim of this paper is to outline the particularities and draw embryological, histopatological and treatment conclusions regarding extragonadal germ cell tumors. PATIENT AND METHODS: A 43-year-old patient without any additional pathology was admitted for anemia of unknown etiology...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27999715/secretory-paraspinal-paraganglioma-of-thoracolumar-spine-case-report-and-review-of-literature
#14
Saad Akhtar, Sidra Sattar, Ehsan Bari, Naila Kayani, Sarosh Moeen
BACKGROUND: Pheochromocytomas are catecholamine secreting tumors of the adrenal medulla chromaffin cells, however, when present extra-adrenally they are called paragangliomas. Paragangliomas rarely produce catecholamine in excess, which is evident by clinical symptoms, urine, and blood biochemistry. Total resection of these tumors can lead to complete clinical and biochemical resolution. This case report presents the clinical features, radiological findings, and neurological outcome in a middle-aged female with a secretory paraganglioma...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27998444/-clinical-and-imaging-features-of-abdominal-rhabdomyosarcoma-of-non-organ-origin-in-children
#15
J Shi, J Du, W Wu, Q Wang
Objective: To evaluate the clinical and imaging features of abdominal rhabdomyosarcoma of non-organ origin in children. Methods: We retrospectively analyzed the clinical and imaging features of 12 pediatric patients with abdominal rhabdomyosarcoma confirmed by surgery and pathology at our hospital. Results: There were 9 boys and 3 girls, with an average age of (5.47±3.92) years old (range, 1 to 15). According to Intergroup Rhabdomyosarcoma Study (IRS) staging system, they were of stage Ⅲ to stage Ⅳ, and most were of embryonal type...
November 23, 2016: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/27995452/an-optimal-approach-for-laparoscopic-d3-lymphadenectomy-plus-complete-mesocolic-excision-d3-cme-for-right-sided-colon-cancer
#16
Daxing Xie, Chaoran Yu, Chun Gao, Hasan Osaiweran, Junbo Hu, Jianping Gong
BACKGROUND: It is common knowledge that high ligation of blood vessels at the D3 level and complete mesocolic excision (CME) are two critical points of right hemicolectomy for right colon cancer (RCC). (1-5) To date, a safe strategy for completing these two procedures under laparoscopic surgery has not been extensively described. The authors provide a video to demonstrate laparoscopic right hemicolectomy (D3 + CME) with an optimal mesentery-defined approach. By identifying three "tri-junctions," this approach facilitates dissection of the entire mesocolon along the embryologic planes as far centrally as possible and enables the high tie of feeding vessels at bifurcation...
December 19, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27983885/multifocal-kaposiform-hemangioendothelioma-causing-massive-fetal-chylous-ascites
#17
Hyo Jung An, Eun Jung Jung, Mi Seon Kang, Hwa Jin Cho, Kyung Han Nam, Jung Mi Byun, Dae Hoon Jeong, Young Nam Kim
Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor that usually occurs in soft tissues of the extremity and rarely in the retroperitoneum. We report a unique case of isolated massive fetal ascites attributed to KHE, involving the retroperitoneum and multiple visceral organs, along with the Kasabach-Merritt phenomenon. We suspect that retroperitoneal KHE might have caused massive fetal ascites because of its high potential to invade the lymphatic vessels aggressively in the retroperitoneal space, which possibly permits intestinal lymph leakage into the peritoneal cavities...
December 16, 2016: Fetal and Pediatric Pathology
https://www.readbyqxmd.com/read/27974691/percutaneous-laser-ablation-a-new-contribution-to-unresectable-high-risk-metastatic-retroperitoneal-lesions
#18
Tian'an Jiang, Zhuang Deng, Guo Tian, Fen Chen, Haiwei Bao, Ju Li, Weilin Wang
BACKGROUND & AIMS: Metastasis in retroperitoneal lymph nodes is one of the signs of advanced stage or terminal stage of malignancy. We performed a trial to assess the safety and efficacy of ultrasonography (US)-guided local neodymium-doped yttrium aluminum garnet (Nd:YAG) laser ablation for metastatic lymph nodes in the retroperitoneal region. METHODS: We evaluated 4 cases of retroperitoneal metastatic lymph nodes treated using US-guided Nd:YAG laser ablation. Additionally, we reviewed the PubMed database for articles on thermal ablation of retroperitoneal lesions until March 2016, without language limitations...
December 10, 2016: Oncotarget
https://www.readbyqxmd.com/read/27974110/-clinical-features-and-outcomes-of-neuroblastoma-patients-aged-above-5-years
#19
Yi Zhang, Wei-Ling Zhang, Dong-Sheng Huang, Tao Han, Tian Zhi, Jing Li, You Yi, Yuan Wen, Fan Li, Yan-Yan Mei, Yan-Yan DU
OBJECTIVE: To investigate the clinical features and outcomes of neuroblastoma (NB) children aged above 5 years, and to provide a theoretical basis for improving prognosis. METHODS: A retrospective analysis was performed for the clinical data of 54 previously untreated NB children, and their clinical features and outcome were analyzed. The Kaplan-Meier method was used for survival analysis. RESULTS: Among the 54 children, there were 36 boys and 18 girls, and all of them had stage 3 or 4 NB...
December 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27957372/nephroblastoma-arising-from-primary-testicular-germ-cell-tumor-a-case-report-and-literature-review
#20
Houda Alatassi, Brittany E O'Bryan, Jamie C Messer, Zhenglong Wang
Adult extrarenal nephroblastoma is a very rare tumor. Nephroblastoma arising from primary testicular germ cell tumor is exceedingly rare. To our knowledge, only three cases have been reported in the English literature. We report a case of a 19-year-old man who presented with a large right testicle. Image studies showed a large retroperitoneal mass along with liver and lung metastases. Orchiectomy demonstrated a mixed germ cell tumor composed of yolk sac tumor, embryonal carcinoma, and mature and immature teratoma with a significant portion of nephroblastoma...
2016: Case Reports in Pathology
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