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https://www.readbyqxmd.com/read/28719862/green-biosynthesis-of-silver-nanoparticles-using-leaves-extract-of-artemisia-vulgaris-and-their-potential-biomedical-applications
#1
Tahir Rasheed, Muhammad Bilal, Hafiz M N Iqbal, Chuanlong Li
Biosynthesis of nanoparticles from plant extracts is receiving enormous interest due to their abundant availability and a broad spectrum of bioactive reducing metabolites. In this study, the reducing potential of Artemisia vulgaris leaves extract (AVLE) was investigated for synthesizing silver nanoparticles without the addition of any external reducing or capping agent. The appearance of blackish brown color evidenced the complete synthesis of nanoparticles. The synthesized silver nanoparticles were characterized by UV-vis spectroscopy, scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX), transmission electron microscope (TEM), atomic force microscopy (AFM) and Fourier transforms infrared spectroscopy (FT-IR) analysis...
July 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28719725/effects-of-eupatilin-on-the-contractility-of-corpus-cavernosal-smooth-muscle-through-nitric-oxide-independent-pathways
#2
S H Choo, S W Lee, M R Chae, S J Kang, H H Sung, D H Han, J N Chun, J K Park, C Y Kim, H K Kim, I So
Eupatilin (5,7-dihydroxy-3,4,6-trimethoxyflavone) is one of the main compounds present in Artemisia species. Eupatilin has both antioxidative and anti-inflammatory properties and a relaxation effect on vascular contraction regardless of endothelial function. We evaluated the relaxant effects of eupatilin on the corpus cavernosum (CC) of rabbits and the underlying mechanisms of its activity in human corpus cavernosum smooth muscle (CCSM) cells. Isolated rabbit CC strips were mounted in an organ bath system. A conventional whole-cell patch clamp technique was used to measure activation of calcium-sensitive K(+) -channel currents in human CCSM cells...
July 18, 2017: Andrology
https://www.readbyqxmd.com/read/28712406/-increased-expressions-of-substance-p-and-neurokinin-tachykinin-receptor-1-in-eosinophils-of-patients-with-psoriasis
#3
Zhe Zuo, Junling Wang, Huiyun Zhang, Wenjiao Zheng, Zenan Zhang, Shaoheng He
Objective To investigate the expressions of substance P (SP) and its receptor neurokinin/tachykinin receptor 1 (NK1R) in peripheral blood eosinophils of patients with psoriasis. Methods The levels of SP and NK1R in the peripheral blood of both patients with psoriasis and healthy people were detected by flow cytometry. This method was again used to detect the levels of SP and NK1R in the peripheral blood eosinophils of patients with psoriasis after stimulated with the crude extracts of Artemisia pollen, dust mite and Platanus pollen (all at concentrations of 0...
July 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28711019/photo-catalytic-anti-bacterial-and-anti-cancer-properties-of-phyto-mediated-synthesis-of-silver-nanoparticles-from-artemisia-tournefortiana-rchb-extract
#4
Fahimeh Baghbani-Arani, Rabee Movagharnia, Alireza Sharifian, Soheil Salehi, Seyed Ataollah Sadat Shandiz
Metal nanoparticles have largely been investigated due to their potential medicinal activities. This study demonstrates the biological properties of green-synthesized silver nanoparticles (AgNPs) by using Artemisia tournefortiana Rchb ethanol extract. Instrumentations such as ultraviolet-visible spectra analysis, high-resolution transmission electron microscopy, scanning electron microscopy, energy-dispersive X-ray analysis, X-ray diffraction, and Fourier transform infrared spectroscopy were used to reveal the synthesized AgNPs...
July 6, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28710946/photosynthetic-parameters-and-redox-homeostasis-of-artemisia-santonica-l-under-conditions-of-elton-region
#5
Olga Rozentsvet, Anatoly Kosobryukhov, Ilya Zakhozhiy, Galina Tabalenkova, Viktor Nesterov, Elena Bogdanova
Structural and functional parameters and redox homeostasis in leaves of Artemisia santonica L. under environment conditions of Elton lake (the southeast region of the European part of Russia) were measured. The highest photosynthetic apparatus (PA) activity in A. santonica leaves on CO2 gas exchange as well as the highest content of green pigments was observed in the morning. Maximum share of violaxanthin cycle key pigments - zeaxanthin (Zx) and antheraxanthin (Ax) was observed in the afternoon and decreased in the evening...
July 6, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28708672/artemisinin-disrupts-androgen-responsiveness-of-human-prostate-cancer-cells-by-stimulating-the-26s-proteasome-mediated-degradation-of-the-androgen-receptor-protein
#6
Andrea M Steely, Jamin A Willoughby, Shyam N Sundar, Vasiliki I Aivaliotis, Gary L Firestone
Androgen receptor (AR) expression and activity is highly linked to the development and progression of prostate cancer and is a target of therapeutic strategies for this disease. We investigated whether the antimalarial drug artemisinin, which is a sesquiterpene lactone isolated from the sweet wormwood plant Artemisia annua, could alter AR expression and responsiveness in cultured human prostate cancer cell lines. Artemisinin treatment induced the 26S proteasome-mediated degradation of the receptor protein, without altering AR transcript levels, in androgen-responsive LNCaP prostate cancer cells or PC-3 prostate cancer cells expressing exogenous wild-type AR...
July 13, 2017: Anti-cancer Drugs
https://www.readbyqxmd.com/read/28707966/targeted-molecular-ablation-of-cancer-stem-cells-for-curing-gastrointestinal-cancers
#7
Yong Seok Kim, Ho Jae Lee, Jong-Min Park, Young-Min Han, Napapan Kangwan, Ji Young Oh, Dong Yoon Lee, Ki Baik Hahm
Abundance of the ATPase-binding cassette (ABC) transporters and deranged self-renewal pathways characterize the presence of cancer stem cells (CSCs) in gastrointestinal cancers (GI cancers), which play crucial roles in tumorigenesis, chemotherapy resistance, tumor recurrence, and cancer metastasis. Therefore, in order to ensure high cure rates, chemoquiescence, CSCs should be ablated. Recent advances in either understanding CSCs or biomarker identification enable scientists to develop techniques for ablating CSCs and clinicians to provide cancer cure, especially in GI cancers characterized by inflammation-driven carcinogenesis...
July 14, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28690346/contrasting-habitat-associations-of-sagebrush-steppe-songbirds-in-the-intermountain-west
#8
Robert A Miller, Laura Bond, Patrick N Migas, Jay D Carlisle, Gregory S Kaltenecker
Sagebrush (Artemisia spp.) steppe is one of North America's most imperiled ecosystems, as the result of many factors including grazing, development, fire, and invasion of exotic plants. Threats to sagebrush steppe are expected to increase because of climate change and further human development. Many songbirds use sagebrush steppe opportunistically, but a few obligate species are dependent on it. To quantify the habitat associations of three sagebrush obligates, the Sage Thrasher (Oreoscoptes montanus), Sagebrush Sparrow (Artemisiospiza nevadensis), and Brewer's Sparrow (Spizella breweri), and nine other songbird species that use this habitat, we surveyed across a broad region of Idaho...
March 2017: Western Birds
https://www.readbyqxmd.com/read/28686181/how-can-synergism-of-traditional-medicines-benefit-from-network-pharmacology
#9
REVIEW
Haidan Yuan, Qianqian Ma, Heying Cui, Guancheng Liu, Xiaoyan Zhao, Wei Li, Guangchun Piao
Many prescriptions of traditional medicines (TMs), whose efficacy has been tested in clinical practice, have great therapeutic value and represent an excellent resource for drug discovery. Research into single compounds of TMs, such as artemisinin from Artemisia annua L., has achieved great success; however, it has become evident that a TM prescription (which frequently contains various herbs or other components) has a synergistic effect in effecting a cure or reducing toxicity. Network pharmacology targets biological networks and analyzes the links among drugs, targets, and diseases in those networks...
July 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28675464/chemical-composition-antimicrobial-and-insecticidal-activity-against-the-lesser-mealworm-alphitobius-diaperinus-panzer-coleoptera-tenebrionidae-of-origanum-vulgare-l-ssp-hirtum-link-and-artemisia-dracunculus-l-essential-oils
#10
Maria Szczepanik, Maciej Walczak, Beata Zawitowska, Marta Michalska-Sionkowska, Antoni Szumny, Czesław Wawrzeńczyk, Maria Swiontek Brzezinska
BACKGROUND: Essential oils (EOs) from Artemisia dracunculus L. and Origanum vulgare L. ssp. hirtum were obtained and the qualitative and quantitative chemical composition of the extracts was investigated. The insecticidal activity of EOs against the larval stages of Alphitobius diaperinus (Panzer) was studied. Moreover, the antimicrobial activity of these oils against pathogens transmitted by this pest was also investigated. RESULTS: The obtained results indicate the possibility of using Greek oregano EO with a high content of carvacrol as a feed additive in poultry nutrition...
July 4, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28670366/inhibitory-effect-of-dihydroartemisinin-on-chondrogenic-and-hypertrophic-differentiation-of-mesenchymal-stem-cells
#11
Zhen Cao, Chuan Liu, Yun Bai, Ce Dou, Jian-Mei Li, Duo-Wei Shi, Shi-Wu Dong, Qiang Xiang
Chondrocytes located in hyaline cartilage may maintain phenotype while the chondrocytes situated in calcified cartilage differentiate into hypertrophy. Chondrogenic and hypertrophic differentiation of mesenchymal stem cells (MSCs) are two subsequent processes during endochondral ossification. However, it is necessary for chondrocytes to hold homeostasis and to inhibit hypertrophic differentiation in stem cell-based regenerated cartilage. Dihydroartemisinin (DHA) is derived from artemisia apiacea which has many biological functions such as anti-malarial and anti-tumor...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28667412/exogenous-salicylic-acid-mediated-modulation-of-arsenic-stress-tolerance-with-enhanced-accumulation-of-secondary-metabolites-and-improved-size-of-glandular-trichomes-in-artemisia-annua-l
#12
Anjana Kumari, Neha Pandey, Shashi Pandey-Rai
The present study was undertaken to find out individual and interactive effects of arsenic (As) and salicylic acid (SA) on an important medicinal plant, Artemisia annua. As uptake and its accumulation was detected and found to be maximum in roots at higher As concentration (150 μM). Under As treatments, H2O2 and MDA content were induced. Biomass and chlorophyll content were negatively affected under As treatments. Furthermore, enzymatic (SOD, CAT, APX, and GR) and non-enzymatic antioxidants were also enhanced under As treatments...
June 30, 2017: Protoplasma
https://www.readbyqxmd.com/read/28653938/report-screening-of-the-anti-hyperglycemic-activity-of-some-medicinal-plants-of-jordan
#13
Ahmad S Alkofahi, Khalid K Abdul-Razzak, Karem H Alzoubi, Omar F Khabour
Diabetes represents a group of common diseases that are characterized by dysregulation of blood glucose levels. Plants are traditionally used for management of diseases including diabetes. In this study, we screened the anti-diabetic effect of extracts of 21 plants grown in Jordan. Extracts of plants were screened for their antihyperglycemic activity. Diabetes was induced in Sprague Dawley rats using Alloxan. Plant extracts were dosed at 1gm/kg. Blood glucose was measured at baseline and at every hour for 3 hours...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28651437/comparative-study-on-artemisia-halodendron-turcz-and-its-two-related-plants-by-gc-ms-analysis-and-protective-effect-against-carbon-tetrachloride-induced-hepatotoxicity-in-mice
#14
Yayu Wang, Lu Lou, Jing Wang, Jincai Lu, Jing Li, Lingyun Jia
A rapid method had been used for comparative study on Artemisia halodendron Turcz. and its two related plants by gas phase-mass spectrometry (GC-MS). The comparison of the volatile oils obtained in three plants by GC-MS were similar in 20 compositions. However, n-Hexadecanoic acid (10.40%), Biphenyl (7.867%) and 9,12-Octadecadienoic acid (7.25%) were the predominant in the volatile oils of A. halodendron Turcz., whereas these constituents did not exist in the other two plants. And the study investigated the effect of three plants against CCl4-induced hepatotoxicity in mice...
June 26, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28644710/study-of-artemisinin-and-sugars-accumulation-in-artemisia-vulgaris-and-artemisia-dracunculus-hairy-root-cultures
#15
Kateryna O Drobot, Nadiia A Matvieieva, Andriy M Ostapchuk, Maxim A Kharkhota
We studied the effect of genetic transformation on biologically active compounds (artemisinin and its co-products (ART) as well as sugars) accumulation in Artemisia vulgaris and A.dracunculus "hairy" root cultures. Glucose, fructose, sucrose and mannitol were accumulated in A. vulgaris and A. dracunculus "hairy" root lines. Genetic transformation has led in some cases to the sugars content increasing or appearing of non-relevant for the control plants carbohydrates. Sucrose content was 1.6 times higher in A...
June 23, 2017: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/28642777/transcriptome-analysis-of-genes-associated-with-the-artemisinin-biosynthesis-by-jasmonic-acid-treatment-under-the-light-in-artemisia-annua
#16
Xiaolong Hao, Yijun Zhong, Xueqing Fu, Zongyou Lv, Qian Shen, Tingxiang Yan, Pu Shi, Yanan Ma, Minghui Chen, Xueying Lv, Zhangkuanyu Wu, Jingya Zhao, Xiaofen Sun, Ling Li, Kexuan Tang
Artemisinin is a sesquiterpene lactone endoperoxide extracted from a traditional Chinese medicinal plant Artemisia annua. Artemisinin-based combination therapies (ACTs) are recommended as the best treatment of malaria by the World Health Organization (WHO). Both the phytohormone jasmonic acid (JA) and light promote artemisinin biosynthesis in A. annua. Interestingly, we found that the increase of artemisinin biosynthesis by JA was dependent on light. However, the relationship between the two signal pathways mediated by JA and light remains unclear...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28642094/investigation-of-the-component-in-artemisia-annua-l-leading-to-enhanced-antiplasmodial-potency-of-artemisinin-via-regulation-of-its-metabolism
#17
Tian-Yu Cai, Yun-Rui Zhang, Jian-Bo Ji, Jie Xing
ETHNOPHARMACOLOGICAL RELEVANCE: The chemical matrix of the herb Artemisia annua L. (A. annua), from which artemisinin (QHS) is isolated, can enhance both the bioavailability and efficacy of QHS. However, the exact mechanism of this synergism remains unknown. The biotransformation of QHS and potential "enzyme inhibitors" in plant matrix could be of great importance in understanding the improved efficacy of QHS in A. annua, which has been limited to the synergism with flavonoid components...
June 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28635610/chemical-components-antioxidant-potential-and-hepatoprotective-effects-of-artemisia-campestris-essential-oil-against-deltamethrin-induced-genotoxicity-and-oxidative-damage-in-rats
#18
Mongi Saoudi, Marwa Ncir, Manel Ben Ali, Malek Grati, Kamel Jamoussi, Noureddine Allouche, Abdelfattah El Feki
In the present study, we evaluated the antioxidant potential of Artemisia campestris essential oil (ACEO) and the possible protective effects against deltamethrin induced hepatic toxic effects. The ACEO showed radical scavenging activity with IC50 = 47.66 ± 2.51 µg/ml, ferric reducing antioxidant power (FRAP) potential (EC50 = 5.36 ± 0.77 µg/ml), superoxide scavenging activity (IC50 = 0.175 ± 0.007 µg/ml) and ˙OH scavenging activity (IC50 = 0.034 ± 0.007 µg/ml). The obtained results of phenolic profile demonstrated that phenolic compounds are the major contributor to the antioxidant activity of ACEO...
July 2017: General Physiology and Biophysics
https://www.readbyqxmd.com/read/28635582/protective-effects-of-ethanol-extracts-of-artemisia-asiatica-nakai-ex-pamp-on-ageing-induced-deterioration-in-mouse-oocyte-quality
#19
Hyuk-Joon Jeon, Seung Yeop You, Dong Hyun Kim, Hong Bae Jeon, Jeong Su Oh
Following ovulation, oocytes undergo a time-dependent deterioration in quality referred to as post-ovulatory ageing. Although various factors influence the post-ovulatory ageing of oocytes, oxidative stress is a key factor involved in deterioration of oocyte quality. Artemisia asiatica Nakai ex Pamp. has been widely used in East Asia as a food ingredient and traditional medicine for the treatment of inflammation, cancer, and microbial infections. Recent studies have shown that A. asiatica exhibits antioxidative effects...
June 21, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28631409/exploration-of-a-ternary-deep-eutectic-solvent-of-methyltriphenylphosphonium-bromide-chalcone-formic-acid-for-the-selective-recognition-of-rutin-and-quercetin-in-herba-artemisiae-scopariae
#20
Wanwan Ma, Tangand Baokun, Kyung Ho Row
A methyltriphenylphosphonium bromide/chalcone/formic acid as a green ternary deep eutectic solvent was applied as a functional monomer and dummy template simultaneously in the synthesis of a new molecularly imprinted polymer. Ternary deep eutectic solvent based molecularly imprinted polymers were used as a solid-phase extraction sorbent in the separation and purification of rutin and quercetin from Herba Artemisiae Scopariae combined with high-performance liquid chromatography. FTIR spectroscopy and field-emission scanning electron microscopy were applied to characterize the deep eutectic solvent based molecularly imprinted polymers synthesized using different molar ratios of chalcone...
June 20, 2017: Journal of Separation Science
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