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https://www.readbyqxmd.com/read/28635610/chemical-components-antioxidant-potential-and-hepatoprotective-effects-of-artemisia-campestris-essential-oil-against-deltamethrin-induced-genotoxicity-and-oxidative-damage-in-rats
#1
Mongi Saoudi, Marwa Ncir, Manel Ben Ali, Malek Grati, Kamel Jamoussi, Noureddine Allouche, Abdelfattah El Feki
In the present study, we evaluated the antioxidant potential of Artemisia campestris essential oil (ACEO) and the possible protective effects against deltamethrin induced hepatic toxic effects. The ACEO showed radical scavenging activity with IC50 = 47.66 ± 2.51 µg/ml, ferric reducing antioxidant power (FRAP) potential (EC50 = 5.36 ± 0.77 µg/ml), superoxide scavenging activity (IC50 = 0.175 ± 0.007 µg/ml) and ˙OH scavenging activity (IC50 = 0.034 ± 0.007 µg/ml). The obtained results of phenolic profile demonstrated that phenolic compounds are the major contributor to the antioxidant activity of ACEO...
July 2017: General Physiology and Biophysics
https://www.readbyqxmd.com/read/28635582/protective-effects-of-ethanol-extracts-of-artemisia-asiatica-nakai-ex-pamp-on-ageing-induced-deterioration-in-mouse-oocyte-quality
#2
Hyuk-Joon Jeon, Seung Yeop You, Dong Hyun Kim, Hong Bae Jeon, Jeong Su Oh
Following ovulation, oocytes undergo a time-dependent deterioration in quality referred to as post-ovulatory ageing. Although various factors influence the post-ovulatory ageing of oocytes, oxidative stress is a key factor involved in deterioration of oocyte quality. Artemisia asiatica Nakai ex Pamp. has been widely used in East Asia as a food ingredient and traditional medicine for the treatment of inflammation, cancer, and microbial infections. Recent studies have shown that A. asiatica exhibits antioxidative effects...
June 21, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28631409/exploration-of-a-ternary-deep-eutectic-solvent-of-methyltriphenylphosphonium-bromide-chalcone-formic-acid-for-the-selective-recognition-of-rutin-and-quercetin-in-herba-artemisiae-scopariae
#3
Wanwan Ma, Tangand Baokun, Kyung Ho Row
A methyltriphenylphosphonium bromide/chalcone/formic acid as a green ternary deep eutectic solvent was applied as a functional monomer and dummy template simultaneously in the synthesis of a new molecularly imprinted polymer. Ternary deep eutectic solvent based molecularly imprinted polymers were used as a solid-phase extraction sorbent in the separation and purification of rutin and quercetin from Herba Artemisiae Scopariae combined with high-performance liquid chromatography. FTIR spectroscopy and field-emission scanning electron microscopy were applied to characterize the deep eutectic solvent based molecularly imprinted polymers synthesized using different molar ratios of chalcone...
June 20, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28628023/-ragweed-allergy-in-the-south-of-russia-in-the-chechen-republic
#4
D Macharadze, H Janaeva, K Avilov
Allergy to ragweed pollen and other weeds is a global problem due to the rapid spread of these grasses around the world. In addition, pollen of short ragweed (Ambrosia, Amb) and mugwort (Artemisia, Art) - one of the main causes of respiratory allergy - seasonal allergic rhinoconjunctivitis (hay fever) with/without bronchial asthma patients living in the South of Russia. Epidemiological studies on the prevalence of Allergy to Amb and Art among patients living in Chechen Republic, absent. Aim - of this retrospective study was to investigate the prevalence of sensitization to weed pollen in patients of Chechnya...
May 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28626485/isolation-and-characterization-of-isofraxidin-7-o-6-o-p-coumaroyl-%C3%AE-glucopyranoside-from-artemisia-capillaris-thunberg-a-novel-nontoxic-hyperpigmentation-agent-that-is-effective-in-vivo
#5
Soon-Ho Yim, Nadia Tabassum, Woong-Hee Kim, Haaglim Cho, Ji-Hyung Lee, Galzad J Batkhuu, Hyun Jung Kim, Won Keun Oh, Da-Woon Jung, Darren R Williams
Abnormalities in skin pigmentation can produce disorders such as albinism or melasma. There is a research need to discover novel compounds that safely and effectively regulate pigmentation. To identify novel modulators of pigmentation, we attempted to purify compounds from a bioactive fraction of the Korean medicinal plant Artemisia capillaris Thunberg. The novel compound isofraxidin 7-O-(6'-O-p-coumaroyl)-β-glucopyranoside (compound 1) was isolated and its pigmentation activity was characterized in mammalian melanocytes...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28623783/scoparone-attenuates-hepatic-stellate-cell-activation-through-inhibiting-tgf-%C3%AE-smad-signaling-pathway
#6
Xing Liu, Xiuxia Zhao
Activation of hepatic stellate cells (HSCs) plays a critical role in liver fibrosis. Scoparone, a major constituent isolated from Artemisia capillaris, was reported to possess hepatoprotective effect. However, the role of scoparone in liver fibrosis remains unknown. In the present study, we investigated the effects of scoparone on liver fibrosis in HSCs. Our results demonstrated that scoparoene inhibited the proliferation of HSCs exposed to transforming growth factor (TGF)-β1. In addition, scoparoene significantly suppressed TGF-β1-induced the expression of α-smooth muscle actin (α-SMA) and collagen I in HSC-T6 cells, as well as attenuated the expression of NADPH oxidase (NOX) isoforms expression and ROS production in TGF-β1-stimialted HSC-T6 cells...
June 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28620857/distribution-of-potentially-toxic-elements-ptes-in-tailings-soils-and-plants-around-gol-e-gohar-iron-mine-a-case-study-in-iran
#7
Naghmeh Soltani, Behnam Keshavarzi, Farid Moore, Armin Sorooshian, Mohamad Reza Ahmadi
This study investigated the concentration of potentially toxic elements (PTEs) including Al, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Sb, V, and Zn in 102 soils (in the Near and Far areas of the mine), 7 tailings, and 60 plant samples (shoots and roots of Artemisia sieberi and Zygophylum species) collected at the Gol-E-Gohar iron ore mine in Iran. The elemental concentrations in tailings and soil samples (in Near and Far areas) varied between 7.4 and 35.8 mg kg(-1) for As (with a mean of 25.39 mg kg(-1) for tailings), 7...
June 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28620813/an-in-silico-insight-into-the-substrate-binding-characteristics-of-the-active-site-of-amorpha-4-11-diene-synthase-a-key-enzyme-in-artemisinin-biosynthesis
#8
Habib Eslami, Seyed Kaveh Mohtashami, Maryam Taghavi Basmanj, Maryam Rahati, Hamzeh Rahimi
The enzyme amorphadiene synthase (ADS) conducts the first committed step in the biosynthetic conversion of the substrate farnesyl pyrophosphate (FPP) to artemisinin, which is a highly effective natural product against multidrug-resistant strains of malaria. Due to the either low abundance or low turn-over rate of the enzyme, obtaining artemisinin from both natural and synthetic sources is costly and laborious. In this in silico study, we strived to elucidate the substrate binding site specificities of the ADS, with the rational that unraveling enzyme features paves the way for enzyme engineering to increase synthesis rate...
July 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28609699/study-on-major-antitumor-components-in-yinchenhao-decoction-in-vitro-and-in-vivo-based-on-hollow-fiber-cell-fishing-coupled-with-high-performance-liquid-chromatography
#9
Di Wu, Xuan Chen, Shuang Hu, Xiaohong Bai
Hollow fiber cell fishing (HFCF) based on human hepatoma cell HepG-2 or human renal tubular cell ACHN coupled with high performance liquid chromatography/ultraviolet detection (HPLC/UV) was developed and used for simultaneous study of the major antitumor active components in a formula of Yinchenhao decoction (YCHD) in vitro and in vivo, and in its constituent herbs, namely, Artemisia capillaris Thunb, Gardenia jasminoides Ellis, Radix et Rhizoma Rhei in vitro. Before application, chlorogenic acid, geniposide, p-hydroxyacetophenone, crocin and rhein were chosen as model compounds, the various validations, e...
June 6, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28606189/therapeutic-efficacy-of-artemisia-absinthium-against-hymenolepis-nana-in-vitro-and-in-vivo-studies-in-comparison-with-the-anthelmintic-praziquantel
#10
E V N Beshay
Hymenolepis nana is a common intestinal tapeworm that affects humans. Drugs are available for the treatment of this infection, including praziquantel (PZQ), nitazoxanide and niclosamide. Although the drug of choice is praziquantel, due to its high cure rates, indicators of the development of PZQ resistance by different parasites have begun to appear over recent decades. Therefore, this study was a trial to find an alternative to PZQ by assessing the activity of the crude aqueous extract of the medicinal herb Artemisia absinthium against H...
June 13, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28599058/the-timing-of-leaf-damage-affects-future-herbivory-in-mountain-sagebrush-artemisia-tridentata
#11
Marshall S McMunn
Many plants respond to herbivory by increasing expression of defensive traits. The defensive response of plants can vary depending on plant condition, seasonality, and time of day. Due to a lack of field-based studies, it is unclear how temporal variability in defensive response may alter future rates of herbivory within ecological communities. In a series of simulated herbivory experiments, I quantified how the timing of leaf damage in mountain sagebrush (Artemisia tridentata ssp. vaseyana) affects future herbivory...
June 9, 2017: Ecology
https://www.readbyqxmd.com/read/28597449/physiological-targets-of-salicylic-acid-on-artemisia-aucheri-boiss-as-a-medicinal-and-aromatic-plant-grown-under-in-vitro-drought-stress
#12
Jalil Abbaspour, Ali Akbar Ehsanpour
BACKGROUND: Artemisia aucheri BOISS is a medicinal and aromatic plant, which is endemic to mountainous areas of Iran and surroundings. In this study, we investigated the alleviating effects of salicylic acid (SA) pretreatment (0.01 and 0.1 mM) on A. aucheri under in vitro drought stress induced by 2 and 4% polyethylene glycol (PEG/6000). RESULTS: Plants exposed to PEG stress showed higher levels of H2O2, MDA and electrolyte leakage compared with control. While SA pretreatment decreased these parameters under PEG stress significantly...
December 2016: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/28588629/in-vitro-and-in-vivo-activity-of-artemisia-sieberi-against-trichomonas-gallinae
#13
M R Youssefi, M Abouhosseini Tabari, A A Moghadamnia
In Iranian folk medicine Artemisia sieberi has been used for treatment of parasite infections in human and animals. The present study was designed to evaluate the in vitro and in vivo effects of A. sieberi essential oil (EO) against Trichomonas gallinae. Trichomonas gallinae were recovered by wet mount method from infected native pigeons. The in vitro assays were accomplished in multi-well plates containing metronidazole (MTZ) as a standard antitrichomonal and EO in final concentrations of 2.5, 5, 10, 20, 50, and 100 μg/ml of culture medium containing 10(4) parasites...
2017: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/28578165/antihypertensive-and-vasorelaxant-effects-of-aqueous-extract-of-artemisia-campestris-l-from-eastern-morocco
#14
Ikram Dib, Monique Tits, Luc Angenot, Jean Noel Wauters, Asmae Assaidi, Hassane Mekhfi, Mohammed Aziz, Mohammed Bnouham, Abdelkhaleq Legssyer, Michel Frederich, Abderrahim Ziyyat
ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia campestris L. (Asteraceae) has many traditional uses, among which treatment of diabetes and hypertension. AIM OF THE STUDY: This study was conducted in order to confirm the antihypertensive and hypotensive effects of A. campestris L. aqueous extract (AcAE) and to explore the underlying mechanism of action of its vasorelaxant effect, besides the acute toxicity. Also, the chemical composition of AcAE was investigated. MATERIAL AND METHODS: the chemical content of AcAE was determined by using HPLC and NMR techniques...
May 31, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28573232/antimicrobial-activities-of-some-saudi-arabian-herbal-plants
#15
Abdelaaty A Shahat, Elsayed A Mahmoud, Abdullah A Al-Mishari, Mansour S Alsaid
BACKGROUND: Several edible plants are used in Kingdom of Saudi Arabia since early time to control microbial infections. In the present study, twenty-four Saudi Arabian medicinal plants d according to traditionally used were select and investigated for the antimicrobial activities. MATERIALS AND METHODS: This study was designed at evaluating the antimicrobial activities of the methanol extracts of twenty-four species of sixteen plant families used in the traditional medicine by Saudi Arabian people for the treatment of numerous ailments of the microbial and non-microbial origin against four Gram-positive, four Gram-negative bacteria and four fungi and yeast using the agar well diffusion method...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28569514/cytotoxic-anti-cancer-and-anti-microbial-effects-of-different-extracts-obtained-from-artemisia-rupestris
#16
Shamshabanu Nokerbek, Zuriyadda Sakipova, Marta Chalupová, Marcela Nejezchlebová, Jan Hošek
Artemisia rupestris is a part of traditional Kazakh folk medicine. Extracts obtained from this plant are used to treat various diseases, including cancer. This study evaluates the anti-microbial, cytotoxic, and anti-cancer effects of different extracts of the plant. Different extraction techniques were used and the resultant activities were compared. Extracts of A. rupestris were prepared from the flowers plus the leaves and from the stems. The antimicrobial activity against Candida albicans and Staphylococcus aureus was quantified...
2017: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/28567480/soil-bacterial-community-responses-to-revegetation-of-moving-sand-dune-in-semi-arid-grassland
#17
Chengyou Cao, Ying Zhang, Zhenbo Cui, Shuwei Feng, Tingting Wang, Qing Ren
Grasslands in semi-arid Northern China are widely desertified, thus inducing the formation of a large area of moving sand lands. Revegetation of the sandy land is commonly adopted to restore degraded grasslands. The structure of the soil microbial community might dramatically change during degradation and recovery because microorganisms are one of the major drivers of ecological process through their interactions with plants and soil. Assuming that soil properties are the key determinants of the structure of soil bacterial community within the same soil type, whether the vegetation type causes the significant difference in the structure of soil bacterial community during revegetation and restoration of the degraded grasslands remains poorly understood...
May 31, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28566563/isolation-of-dihydroartemisinic-acid-from-the-artemisia-annua-l-by-product-by-combining-ultrasound-assisted-extraction-with-response-surface-methodology
#18
Shuoqian Liu, Jorge Freire da Silva Ferreira, Liping Liu, Yuwei Tang, Dongming Tian, Zhonghua Liu, Na Tian
Malaria is the most devastating parasitic disease worldwide. Artemisinin is the only drug that can cure malaria that is resistant to quinine-derived drugs. After the commercial extraction of artemisinin from Artemisia annua, the recovery of DHAA (dihydroartemisinic acid) from artemisinin extraction by-product has the potential to increase artemisinin commercial yield. Here we describe the development and optimization of an ultrasound-assisted alkaline procedure for the extraction of DHAA from artemisinin production waste using response surface methodology...
June 1, 2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28560643/in-vitro-seed-germination-and-biochemical-profiling-of-artemisia-absinthium-exposed-to-various-metallic-nanoparticles
#19
Mubashir Hussain, Naveed Iqbal Raja, Zia-Ur-Rehman Mashwani, Muhammad Iqbal, Sidra Sabir, Farhat Yasmeen
In the recent years, nanotechnology has attained much attention in the every field of science. The synthesis, characterisation and applications of metallic nanoparticles (MNPs) have become an important branch of nanotechnology. In the current study, MNPs were synthesised through polyols process and applied in vitro to study their effect on medicinally important plant : Artemisia absinthium. The current study strives to check the effect of MNPs, i.e., Ag, Cu and Au on seed germination, root and shoot length, seedling vigour index (SVI) and biochemical profiling in A...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28555033/annual-wormwood-leaf-inhibits-the-adipogenesis-of-3t3-l1-and-obesity-in-high-fat-diet-induced-obese-rats
#20
Yuno Song, Soo-Jung Lee, Sun-Hee Jang, Tae Hoon Kim, Hong-Duck Kim, Sung-Woo Kim, Chung-Kil Won, Jae-Hyeon Cho
Annual wormwood (AW) (Artemisia annua L.) has anti-malarial, anti-bacterial, anti-oxidant, anti-tumour, and anti-inflammatory activities. In the present study, we evaluated the effects of annual wormwood leaves (AWL) on adipocyte differentiation in 3T3-L1 cells and high-fat diet (HFD)-induced obese rats. 3T3-L1 adipocytes and HFD-induced obese rats were treated with AWL, and its effect on gene expression was analyzed using RT-PCR and Western blotting experiments. Treatment with AWL effectively prevented triglyceride accumulation during adipogenesis in a dose-dependent manner...
May 28, 2017: Nutrients
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