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https://www.readbyqxmd.com/read/28922228/anesthesia-capacity-in-ghana-a-teaching-hospital-s-resources-and-the-national-workforce-and-education
#1
Mark A Brouillette, Alfred J Aidoo, Maria A Hondras, Nana A Boateng, Akwasi Antwi-Kusi, William Addison, Alec R Hermanson
BACKGROUND: Quality anesthetic care is lacking in low- and middle-income countries (LMICs). Global health leaders call for perioperative capacity reports in limited-resource settings to guide improved health care initiatives. We describe a teaching hospital's resources and the national workforce and education in this LMIC capacity report. METHODS: A prospective observational study was conducted at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana, during 4 weeks in August 2016...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28920053/smoking-and-lung-cancer-a-geo-regional-perspective
#2
REVIEW
Zahraa Rahal, Shaza El Nemr, Ansam Sinjab, Hassan Chami, Arafat Tfayli, Humam Kadara
Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) represents the most frequently diagnosed subtype of this morbid malignancy. NSCLC is causally linked to tobacco consumption with more than 500 million smokers worldwide at high risk for this fatal malignancy. We are currently lagging in our knowledge of the early molecular (e.g., genomic) effects of smoking in NSCLC pathogenesis that would constitute ideal markers for early detection. This limitation is further amplified when considering the variable etiologic factors in NSCLC pathogenesis among different regions around the globe...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28912367/lessons-from-pediatric-hiv-a-case-for-curative-intent-in-pediatric-cancer-in-lmics
#3
REVIEW
Henry Miller, Jeremy S Slone, Eric Raabe, Nader Kim El-Mallawany, Parth Mehta, B Ryan Phelps
No abstract text is available yet for this article.
September 14, 2017: Pediatrics
https://www.readbyqxmd.com/read/28911320/practicing-governance-towards-equity-in-health-systems-lmic-perspectives-and-experience
#4
EDITORIAL
Lucy Gilson, Uta Lehmann, Helen Schneider
The unifying theme of the papers in this series is a concern for understanding the everyday practice of governance in low- and middle-income country (LMIC) health systems. Rather than seeing governance as a normative health system goal addressed through the architecture and design of accountability and regulatory frameworks, these papers provide insights into the real-world decision-making of health policy and system actors. Their multiple, routine decisions translate policy intentions into practice - and are filtered through relationships, underpinned by values and norms, influenced by organizational structures and resources, and embedded in historical and socio-political contexts...
September 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28910379/a-one-year-prospective-study-of-colonization-with-antimicrobial-resistant-organisms-on-admission-to-a-vietnamese-intensive-care-unit
#5
Duong Bich Thuy, James Campbell, Nguyen Van Minh Hoang, Truong Thi Thuy Trinh, Ha Thi Hai Duong, Nguyen Chi Hieu, Nguyen Hoang Anh Duy, Nguyen Van Hao, Stephen Baker, Guy E Thwaites, Nguyen Van Vinh Chau, C Louise Thwaites
There is a paucity of data regarding initial bacterial colonization on admission to Intensive Care Units (ICUs) in low and middle-income countries (LMICs). Patients admitted to ICUs in LMICs are at high-risk of subsequent infection with antimicrobial-resistant organisms (AROs). We conducted a prospective, observational study at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam from November 2014 to January 2016 to assess the colonization and antimicrobial susceptibility of Staphylococcus aureus, Escherichia coli, Klebsiella spp...
2017: PloS One
https://www.readbyqxmd.com/read/28904116/integrated-interventions-delivered-in-health-systems-home-and-community-have-the-highest-impact-on-breastfeeding-outcomes-in-low-and-middle-income-countries
#6
REVIEW
Bireshwar Sinha, Ranadip Chowdhury, Ravi Prakash Upadhyay, Sunita Taneja, Jose Martines, Rajiv Bahl, Mari Jeeva Sankar
Background: Improving breastfeeding rates is critical. In low- and middle-income countries (LMICs), only subtle improvements in breastfeeding rates have been observed over the past decade, which highlights the need for accelerating breastfeeding promotion interventions.Objectives: The objective of this article is to update evidence on the effect of interventions on early initiation of and exclusive (<1 and 1-5 mo) and continued (6-23 mo) breastfeeding rates in LMICs when delivered in health systems, in the home or in community environments, or in a combination of settings...
September 13, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28904115/new-option-in-the-lives-saved-tool-list-allows-for-the-conversion-of-prevalence-of-small-for-gestational-age-and-preterm-births-to-prevalence-of-low-birth-weight
#7
REVIEW
Naoko Kozuki, Joanne Katz, Adrienne Clermont, Neff Walker
Background: The Lives Saved Tool (LiST) is a software model that estimates the health impact of scaling up interventions on maternal and child health. One of the outputs of the model is an estimation of births by fetal size [appropriate-for-gestational-age (AGA) or small-for-gestational-age (SGA)] and by length of gestation (term or preterm), both of which influence birth weight. LiST uses prevalence estimates of births in these categories rather than of birth weight categories, because the causes and health consequences differ between SGA and preterm birth...
September 13, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28904114/the-lives-saved-tool-list-as-a-model-for-prevention-of-anemia-in-women-of-reproductive-age
#8
REVIEW
Rebecca Heidkamp, Renee Guida, Erica Phillips, Adrienne Clermont
Background: Anemia in women is a major public health burden worldwide, particularly in low- and middle-income countries (LMICs). It is a complex condition with multiple nutritional and non-nutritional causes, and geographic heterogeneity of burden. The World Health Assembly has set a target of a 50% reduction in anemia among women of reproductive age (WRA) by 2025.Objective: This article seeks to identify the leading causes of anemia among women in LMICs, review the evidence supporting interventions to address anemia in these settings, and ultimately use this information to decide which interventions should be included in the Lives Saved Tool (LiST) model of anemia...
September 13, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28903977/who-mental-health-gap-action-programme-mhgap-intervention-guide-a-systematic-review-of-evidence-from-low-and-middle-income-countries
#9
REVIEW
Roxanne C Keynejad, Tarun Dua, Corrado Barbui, Graham Thornicroft
QUESTION: Despite mental, neurological and substance use (MNS) disorders being highly prevalent, there is a worldwide gap between service need and provision. WHO launched its Mental Health Gap Action Programme (mhGAP) in 2008, and the Intervention Guide (mhGAP-IG) in 2010. mhGAP-IG provides evidence-based guidance and tools for assessment and integrated management of priority MNS disorders in low and middle-income countries (LMICs), using clinical decision-making protocols. It targets a non-specialised primary healthcare audience, but has also been used by ministries, non-governmental organisations and academics, for mental health service scale-up in 90 countries...
September 13, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/28902690/effectiveness-of-population-based-risk-reduction-programs-for-risky-sexual-behavior-among-young-people-in-low-and-middle-income-countries-a-systematic-review-protocol
#10
Yeetey Akpe Kwesi Enuameh, George Adjei, Emmanuel Mahama, Thomas Gyan, Emmanuel Koku
The objective of this review is to synthesize the best available evidence on the effectiveness of population based (public health) risk reduction interventions (programs and services) on sexual risk taking among young people (aged 10 to 24 years old) in low- and middle-income countries (LMICs).The specific review questions are.
September 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28899545/a-different-rhythm-of-life-sleep-patterns-in-the-first-4-years-of-life-and-associated-sociodemographic-characteristics-in-a-large-brazilian-birth-cohort
#11
Elena Netsi, Ina S Santos, Alan Stein, Fernando C Barros, Aluísio J D Barros, Alicia Matijasevich
OBJECTIVE: Sleep is an important marker of healthy development and has been associated with emotional, behavioral, and cognitive development. There is limited longitudinal data on children's sleep with only a few reports from low- and middle-income countries (LMICs). We investigate sleep parameters and associated sociodemographic characteristics in a population-based longitudinal study in Pelotas, Brazil. METHODS: Data from the Pelotas 2004 Birth Cohort were used (N = 3842)...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28895277/evaluation-of-a-fever-management-algorithm-in-a-pediatric-cancer-center-in-a-low-resource-setting
#12
Sheena Mukkada, Cristel Kate Smith, Delta Aguilar, April Sykes, Li Tang, Mae Dolendo, Miguela A Caniza
BACKGROUND: In low- and middle-income countries (LMICs), inconsistent or delayed management of fever contributes to poor outcomes among pediatric patients with cancer. We hypothesized that standardizing practice with a clinical algorithm adapted to local resources would improve outcomes. Therefore, we developed a resource-specific algorithm for fever management in Davao City, Philippines. The primary objective of this study was to evaluate adherence to the algorithm. PROCEDURE: This was a prospective cohort study of algorithm adherence to assess the types of deviation, reasons for deviation, and pathogens isolated...
September 12, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28893473/data-and-product-needs-for-influenza-immunization-programs-in-low-and-middle-income-countries-rationale-and-main-conclusions-of-the-who-preferred-product-characteristics-for-next-generation-influenza-vaccines
#13
Kathleen M Neuzil, Joseph S Bresee, Fernando de la Hoz, Kari Johansen, Ruth A Karron, Anand Krishnan, Shabir A Madhi, Punam Mangtani, David J Spiro, Justin R Ortiz
In 2017, WHO convened a working group of global experts to develop the Preferred Product Characteristics (PPC) for Next-Generation Influenza Vaccines. PPCs are intended to encourage innovation in vaccine development. They describe WHO preferences for parameters of vaccines, in particular their indications, target groups, implementation strategies, and clinical data needed for assessment of safety and efficacy. PPCs are shaped by the global unmet public health need in a priority disease area for which WHO encourages vaccine development...
September 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28891318/-what-would-an-hiv-cure-mean-to-you-qualitative-analysis-from-a-crowdsourcing-contest-in-guangzhou-china
#14
Alice Zhang, Xin Pan, Feng Wu, Yang Zhao, Fengyu Hu, Linghua Li, Weiping Cai, Joseph D Tucker
Much HIV cure social science research has focused on high-income countries. Local key population perspectives, especially from people living with HIV (PLHIV), are needed in low-and middle-income countries (LMIC). We organized an open contest soliciting responses from key populations, including PLHIV, about what a cure would mean in their lives. Tailored in-person events and social media were used to engage PLHIV, men who have sex with men (MSM), people who inject drugs (PWID), and local residents. We received 471 contributions over four months...
September 11, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28889090/placing-the-radar-under-the-radar-ethics-of-public-health-surveillance
#15
Vijayaprasad Gopichandran
Public health surveillance (PHS) is an essential public health activity, which entails collecting data on diseases and disease-related states in a timely manner to aid in international health regulations and in local health planning. Opinions differ sharply on whether it is a research or non-research activity. In recent years, most low- and middle-income countries (LMICs) have been establishing their own PHS systems, with or without support from external donors, to comply with the stipulations of international health regulations...
August 16, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28888849/outcomes-in-non-metastatic-extremity-osteosarcoma-treatment-naive-patients-treated-with-a-novel-non-high-dose-methotrexate-based-dose-dense-combination-chemotherapy-regimen-ogs-12
#16
Jyoti Bajpai, Arun Chandrasekharan, Vikas Talreja, Vijai Simha, M V Chandrakanth, Bharat Rekhi, Sachin Khurana, Arif Khan, Tushar Vora, Jaya Ghosh, Shripad D Banavali, Sudeep Gupta
PURPOSE: High-dose methotrexate (HDMTX)-based regimens are widely used in osteosarcoma. However, mandatory in-patient treatment with complex pharmacokinetic monitoring requirement precludes its use, especially in resource-constrained settings of low- and middle-income countries (LMICs). METHODS: All treatment naive consecutive patients of osteosarcoma were prospectively treated on a novel institutional regimen (named OGS-12) comprising of eight sequential doublets of the following drugs: doxorubicin, cisplatin and ifosfamide in four courses each, given in the neoadjuvant and adjuvant settings...
September 7, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28886260/avoidable-waste-in-ophthalmic-epidemiology-a-review-of-blindness-prevalence-surveys-in-low-and-middle-income-countries-2000-2014
#17
Jacqueline Ramke, Hannah Kuper, Hans Limburg, Jennifer Kinloch, Wenhui Zhu, Van C Lansingh, Nathan Congdon, Allen Foster, Clare E Gilbert
PURPOSE: Sources of avoidable waste in ophthalmic epidemiology include duplication of effort, and survey reports remaining unpublished, gaining publication after a long delay, or being incomplete or of poor quality. The aim of this review was to assess these sources of avoidable waste by examining blindness prevalence surveys undertaken in low and middle income countries (LMICs) between 2000 and 2014. METHODS: On December 1, 2016 we searched MEDLINE, EMBASE and Web of Science databases for cross-sectional blindness prevalence surveys undertaken in LMICs between 2000 and 2014...
September 8, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28883931/rural-to-urban-migration-is-associated-with-increased-prevalence-of-childhood-wheeze-in-a-latin-american-city
#18
Alejandro Rodriguez, Maritza G Vaca, Martha E Chico, Laura C Rodrigues, Mauricio L Barreto, Philip J Cooper
INTRODUCTION: The urbanisation process has been associated with increases in asthma prevalence in urban and rural areas of low-income and middle-income countries (LMICs). However, although rural to urban migration and migration between cities are considered important determinants of this process, few studies have evaluated the effects of internal migration on asthma in urban populations of LMICs. The present study evaluated the effects of internal migration on the prevalence of wheeze in an urban area of Latin America...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28882188/unifying-a-fragmented-effort-a-qualitative-framework-for-improving-international-surgical-teaching-collaborations
#19
Parisa Nicole Fallah, Mark Bernstein
BACKGROUND: Access to adequate surgical care is limited globally, particularly in low- and middle-income countries (LMICs). To address this issue, surgeons are becoming increasingly involved in international surgical teaching collaborations (ISTCs), which include educational partnerships between surgical teams in high-income countries and those in LMICs. The purpose of this study is to determine a framework for unifying, systematizing, and improving the quality of ISTCs so that they can better address the global surgical need...
September 7, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28879542/competency-based-education-in-low-resource-settings-development-of-a-novel-surgical-training-program
#20
Meghan McCullough, Alex Campbell, Armando Siu, Libby Durnwald, Shubha Kumar, William P Magee, Jordan Swanson
BACKGROUND: The unmet burden of surgical disease represents a major global health concern, and a lack of trained providers is a critical component of the inadequacy of surgical care worldwide. Competency-based training has been advanced in high-income countries, improving technical skills and decreasing training time, but it is poorly understood how this model might be applied to low- and middle-income countries. We describe the development of a competency-based program to accelerate specialty training of in-country providers in cleft surgery techniques...
September 6, 2017: World Journal of Surgery
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