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https://www.readbyqxmd.com/read/28228841/an-update-on-the-management-of-breast-cancer-in-africa
#1
REVIEW
V Vanderpuye, S Grover, N Hammad, PoojaPrabhakar, H Simonds, F Olopade, D C Stefan
BACKGROUND: There is limited information about the challenges of cancer management and attempts at improving outcomes in Africa. Even though South and North Africa are better resourceds to tackle the burden of breast cancer, similar poor prognostic factors are common to all countries. The five-year overall Survival rate for breast cancer patients does not exceed 60% for any low and middle-income country (LMIC) in Africa. In spite of the gains achieved over the past decade, certain characteristics remain the same such as limited availability of breast conservation therapies, inadequate access to drugs, few oncology specialists and adherence to harmful socio-cultural practices...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28223433/global-cancer-in-women-burden-and-trends
#2
Lindsey A Torre, Farhad Islami, Rebecca L Siegel, Elizabeth M Ward, Ahmedin Jemal
There are striking disparities in the global cancer burden in women, yet few publications highlight cancer occurrence in this population, particularly for cancers that are not sex-specific. This paper, the first in a series of two, summarizes the current burden, trends, risk factors, prevention, early detection, and survivorship of all cancers combined and seven sites (breast, cervix, uterine corpus, ovary, colorectum, lung, and liver) that account for about 60% of the cancer burden among women worldwide, using data from the International Agency for Research on Cancer...
February 21, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28216179/the-17th-international-congress-on-infectious-diseases-workshop-on-developing-infection-prevention-and-control-resources-for-low-to-middle-income-countries
#3
Sangeeta Sastry, Nadia Masroor, Gonzalo Bearman, Rana Hajjeh, Alison Holmes, Ziad Memish, Britta Lassmann, Didier Pittet, Fiona Macnab, Rachel Kamau, Evelyn Wesangula, Paras Pokharel, Paul Brown, Frances Daily, Fatma Amer, Jaime Torres, Miguel O'Ryan, Revathi Gunturu, Andre Bulabula, Shaheen Mehtar
Hospital acquired infections (HAIs) are a major concern to healthcare systems around the world. They are associated with significant morbidity and mortality, in addition to increased hospitalization costs. Recent outbreaks including MERS (Middle East Respiratory Syndrome) coronavirus and Ebola have highlighted the importance of infection control. Further, HAIs especially with multi-drug resistant gram negative rods (MDRO-GNRs) have become a top global priority. Though adequate approaches and guidelines have been in existence for many years and have sometimes proven effective in some countries, the implementation of such approaches in low and middle income countries (LMICs) is often restricted due to limited resources and underdeveloped infrastructure...
February 16, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28210884/energy-balance-and-obesity-what-are-the-main-drivers
#4
Isabelle Romieu, Laure Dossus, Simón Barquera, Hervé M Blottière, Paul W Franks, Marc Gunter, Nahla Hwalla, Stephen D Hursting, Michael Leitzmann, Barrie Margetts, Chizuru Nishida, Nancy Potischman, Jacob Seidell, Magdalena Stepien, Youfa Wang, Klaas Westerterp, Pattanee Winichagoon, Martin Wiseman, Walter C Willett
PURPOSE: The aim of this paper is to review the evidence of the association between energy balance and obesity. METHODS: In December 2015, the International Agency for Research on Cancer (IARC), Lyon, France convened a Working Group of international experts to review the evidence regarding energy balance and obesity, with a focus on Low and Middle Income Countries (LMIC). RESULTS: The global epidemic of obesity and the double burden, in LMICs, of malnutrition (coexistence of undernutrition and overnutrition) are both related to poor quality diet and unbalanced energy intake...
February 17, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28209120/factors-influencing-utilisation-of-maternal-health-services-by-adolescent-mothers-in-low-and-middle-income-countries-a-systematic-review
#5
Oluwasola Eniola Banke-Thomas, Aduragbemi Oluwabusayo Banke-Thomas, Charles Anawo Ameh
BACKGROUND: Adolescent mothers aged 15-19 years are known to have greater risks of maternal morbidity and mortality compared with women aged 20-24 years, mostly due to their unique biological, sociological and economic status. Nowhere Is the burden of disease greater than in low-and middle-income countries (LMICs). Understanding factors that influence adolescent utilisation of essential maternal health services (MHS) would be critical in improving their outcomes. METHODS: We systematically reviewed the literature for articles published until December 2015 to understand how adolescent MHS utilisation has been assessed in LMICs and factors affecting service utilisation by adolescent mothers...
February 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28207339/measuring-socioeconomic-inequalities-with-predicted-absolute-incomes-rather-than-wealth-quintiles-a-comparative-assessment-using-child-stunting-data-from-national-surveys
#6
Günther Fink, Cesar G Victora, Kenneth Harttgen, Sebastian Vollmer, Luís Paulo Vidaletti, Aluisio J D Barros
OBJECTIVES: To compare the predictive power of synthetic absolute income measures with that of asset-based wealth quintiles in low- and middle-income countries (LMICs) using child stunting as an outcome. METHODS: We pooled data from 239 nationally representative household surveys from LMICs and computed absolute incomes in US dollars based on households' asset rank as well as data on national consumption and inequality levels. We used multivariable regression models to compare the predictive power of the created income measure with the predictive power of existing asset indicator measures...
February 16, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28205225/global-mental-health-a-call-for-increased-awareness-and-action-for-family-therapists
#7
Jo Ellen Patterson, Todd M Edwards, Susanna Vakili
Global mental health (GMH) is an emerging field that focuses on the need for culturally sensitive mental health services in low- and middle-income countries (LMICs). While many new initiatives have been established worldwide to understand GMH needs and to provide care in LMICs, family therapists have primarily worked with families in high-income countries. The few existing family-based initiatives in GMH focus on psychoeducation and are typically not based on general systems theory. However, emerging trends in family therapy may enable family therapists to impact mental health issues in LMICs...
February 15, 2017: Family Process
https://www.readbyqxmd.com/read/28203627/variations-in-gynecologic-oncology-training-in-low-lic-and-middle-income-mic-countries-lmics-common-efforts-and-challenges
#8
REVIEW
Carolyn Johnston, Joseph S Ng, Ranjit Manchanda, Audrey Tieko Tsunoda, Linus Chuang
Gynecologic cancer, cervical cancer in particular, is disproportionately represented in the developing world where mortality is also high. Screening programs, increased availability of chemotherapy, and an awareness of HIV-related cancers have in part accelerated a need for physicians who can treat these cancers, yet the infrastructure for such training is often lacking. In this paper, we address the variations in gynecology oncology training in LMICs as well as the ubiquitous challenges, in an effort to guide future agendas...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28202089/suicidal-ideation-and-behaviour-among-community-and-health-care-seeking-populations-in-five-low-and-middle-income-countries-a-cross-sectional-study
#9
M Jordans, S Rathod, A Fekadu, G Medhin, F Kigozi, B Kohrt, N Luitel, I Petersen, R Shidhaye, J Ssebunnya, V Patel, C Lund
: Aims Suicidal behaviour is an under-reported and hidden cause of death in most low- and middle-income countries (LMIC) due to lack of national systematic reporting for cause-specific mortality, high levels of stigma and religious or cultural sanctions. The lack of information on non-fatal suicidal behaviour (ideation, plans and attempts) in LMIC is a major barrier to design and implementation of prevention strategies. This study aims to determine the prevalence of non-fatal suicidal behaviour within community- and health facility-based populations in LMIC...
February 16, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28196555/dohad-at-the-intersection-of-maternal-immune-activation-and-maternal-metabolic-stress-a-scoping-review
#10
J A Goldstein, S A Norris, D M Aronoff
The prenatal environment is now recognized as a key driver of non-communicable disease risk later in life. Within the developmental origins of health and disease (DOHaD) paradigm, studies are increasingly identifying links between maternal morbidity during pregnancy and disease later in life for offspring. Nutrient restriction, metabolic disorders during gestation, such as diabetes or obesity, and maternal immune activation provoked by infection have been linked to adverse health outcomes for offspring later in life...
February 15, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28190377/collaborative-approach-to-the-creation-of-an-arteriovenous-fistula-on-a-us-navy-hospital-ship
#11
Kimberly A Thompson, Amrish Krishnan, Charles Stehman, Steven Hanling, Kevin Casey
Early creation of arteriovenous fistulas (AVFs) decreases morbidity and mortality in patients with end-stage renal disease and is the standard of care in the United States. However, this procedure is frequently not accessible in low- and middle-income countries (LMICs). We present the first reported case of successful AVF creation as part of a humanitarian assistance mission. The patient was a 51-year-old male with diabetes, hypertension, and end-stage renal disease on hemodialysis via a temporary dialysis catheter...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28185590/how-can-health-systems-research-reach-the-worst-off-a-conceptual-exploration
#12
REVIEW
Bridget Pratt, Adnan A Hyder
BACKGROUND: Health systems research is increasingly being conducted in low and middle-income countries (LMICs). Such research should aim to reduce health disparities between and within countries as a matter of global justice. For such research to do so, ethical guidance that is consistent with egalitarian theories of social justice proposes it ought to (amongst other things) focus on worst-off countries and research populations. Yet who constitutes the worst-off is not well-defined. METHODS AND RESULTS: By applying existing work on disadvantage from political philosophy, the paper demonstrates that (at least) two options exist for how to define the worst-off upon whom equity-oriented health systems research should focus: those who are worst-off in terms of health or those who are systematically disadvantaged...
November 15, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/28185589/synergies-strengths-and-challenges-findings-on-community-capability-from-a-systematic-health-systems-research-literature-review
#13
REVIEW
Asha S George, Kerry Scott, Vrinda Mehra, Veena Sriram
BACKGROUND: Community capability is the combined influence of a community's social systems and collective resources that can address community problems and broaden community opportunities. We frame it as consisting of three domains that together support community empowerment: what communities have; how communities act; and for whom communities act. We sought to further understand these domains through a secondary analysis of a previous systematic review on community participation in health systems interventions in low and middle income countries (LMICs)...
November 15, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/28183824/global-cancer-in-women-cancer-control-priorities
#14
Farhad Islami, Lindsey A Torre, Jeffrey M Drope, Elizabeth M Ward, Ahmedin Jemal
The global burden of cancer in women has recently received much attention, but there are few comprehensive reviews of the burden and policy approaches to reduce it. This paper, second in series of two, summarizes the most important cancer control priorities with specific examples of proven interventions, with a particular focus on primary prevention in low- and middle-income countries (LMICs). There are a number of effective cancer control measures available to countries of all resource levels. Many of these measures are extremely cost-effective, especially in the case of tobacco control and vaccination...
February 9, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28176250/hot-topic-global-burden-of-treating-hypertension-what-is-the-role-of-the-emergency-department
#15
REVIEW
Aaron M Brody, Vijaya A Kumar, Phillip D Levy
Hypertension (HTN) is the most common modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality worldwide. Lower- and middle-income countries (LMICs) are projected to bear the vast majority of this disease burden, but local and regional health care delivery systems in these countries are ill equipped to meet this need. Emergency care is receiving increased recognition as a crucial component of public and community health. The rapid evolution of emergency care in LMICs provides a unique opportunity to develop innovative strategies, incorporating existing strengths of emergency departments, to address this paradigm shift in the disease burden associated with HTN on a global scale...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28168002/hepatitis-c-virus-seroprevalence-in-the-general-female-population-of-9-countries-in-europe-asia-and-africa
#16
Gary M Clifford, Tim Waterboer, Bolormaa Dondog, You Lin Qiao, Dimitri Kordzaia, Doudja Hammouda, Namory Keita, Nahid Khodakarami, Syed Ahsan Raza, Ang Tshering Sherpa, Witold Zatonski, Michael Pawlita, Martyn Plummer, Silvia Franceschi
BACKGROUND: New oral treatments with very high cure rates have the potential to revolutionize global management of hepatitis C virus (HCV), but population-based data on HCV infection are missing in many low and middle-income countries (LMIC). METHODS: Between 2004 and 2009, dried blood spots were collected from age-stratified female population samples of 9 countries: China, Mongolia, Poland, Guinea, Nepal, Pakistan, Algeria, Georgia and Iran. HCV antibodies were detected by a multiplex serology assay using bead-based technology...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28153930/psychological-interventions-for-post-traumatic-stress-disorder-and-depression-in-young-survivors-of-mass-violence-in-low-and-middle-income-countries-meta-analysis
#17
REVIEW
Nexhmedin Morina, Mina Malek, Angela Nickerson, Richard A Bryant
BACKGROUND: The majority of survivors of mass violence live in low- and middle-income countries (LMICs). AIMS: To synthesise empirical findings for psychological interventions for children and adolescents with post-traumatic stress disorder (PTSD) and/or depression in LMICs affected by mass violence. METHOD: Randomised controlled trials with children and adolescents with symptoms of PTSD and/or depression in LMICs were identified. Overall, 21 812 records were found through July 2016 in the Medline, PsycINFO and PILOTS databases; 21 met the inclusion criteria and were reviewed according to recommended guidelines...
February 2, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28153038/priority-gaps-and-promising-areas-in-maternal-health-research-in-low-and-middle-income-countries-summary-findings-of-a-mapping-of-2292-publications-between-2000-and-2012
#18
EDITORIAL
Matthew F Chersich, Greg Martin
This commentary sums the findings of a series of papers on a study that mapped the global research agenda for maternal health. The mapping reviewed published interventional research across low- and middle-income countries (LMICs) from 2000 to 2012, specifically focusing on investigating the topics covered by this research, the methodologies applied, the funding landscape and trends in authorship attribution.The overarching aim underpinning the mapping activities was to evaluate whether research and funding align with causes of maternal mortality, and thereby highlight gaps in research priorities and governance...
February 2, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28153014/towards-best-practice-in-acute-stroke-care-in-ghana-a-survey-of-hospital-services
#19
Leonard Baatiema, Michael Otim, George Mnatzaganian, Ama De-Graft Aikins, Judith Coombes, Shawn Somerset
BACKGROUND: Stroke and other non-communicable diseases are important emerging public health concerns in sub-Saharan Africa where stroke-related mortality and morbidity are higher compared to other parts of the world. Despite the availability of evidence-based acute stroke interventions globally, uptake in low-middle income countries (LMIC) such as Ghana is uncertain. This study aimed to identify and evaluate available acute stroke services in Ghana and the extent to which these services align with global best practice...
February 2, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28152844/health-information-seeking-preferences-of-mexican-cancer-survivors-creating-an-evidence-base-for-the-design-of-high-quality-communication-programs
#20
Edgar Baltazar-Avalos, Lorena Ali Guadalupe Rocha-Rojo, Patricia Rojo-Castillo, Yanin Chavarri Guerra
: 190 Background: In order to improve the quality of the communication between the healthcare system and cancer survivors, it is fundamental to understand their preferred sources of health information. In low and middle-income countries (LMICs), little is known regarding which sources are used and trusted the most. This information is crucial to develop effective communication aimed at achieving high-quality equitable cancer care. Our objective was to explore the preferred sources of health information in Mexico, and to understand which factors influence these choices...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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