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https://www.readbyqxmd.com/read/27913365/portable-mtbi-assessment-using-temporal-and-frequency-analysis-of-speech
#1
Louis Daudet, Nikhil Yadav, Matthew Perez, Christian Poellabauer, Sandra Schneider, Alan Huebner
This paper shows that extraction and analysis of various acoustic features from speech using mobile devices can allow the detection of patterns that could be indicative of neurological trauma. This may pave the way for new types of biomarkers and diagnostic tools. Toward this end, we created a mobile application designed to diagnose mild traumatic brain injuries (mTBI) such as concussions. Using this application, data was collected from youth athletes from 47 high schools and colleges in the the Midwestern United States...
December 1, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27913363/detecting-breathing-and-snoring-episodes-using-a-wireless-tracheal-sensor-a-feasibility-study
#2
Marcel Mlynczak, Ewa Migacz, Maciej Migacz, Wojciech Kukwa
OBJECTIVE: Sleep-disordered breathing is both a clinical and a social problem. This implies the need for convenient solutions to simplify screening and diagnosis. The aim of the study was to investigate the sensitivity and specificity of a novel wireless system in detecting breathing and snoring episodes during sleep. METHODS: A wireless acoustic sensor was elaborated and implemented. Segmentation (based on spectral thresholding and heuristics) and classification of all breathing episodes during recording were implemented through a mobile application...
November 29, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27913029/pharmacovigilance-and-biomedical-informatics-a-model-for-future-development
#3
Paul Beninger, Michael A Ibara
PURPOSE: The discipline of pharmacovigilance is rooted in the aftermath of the thalidomide tragedy of 1961. It has evolved as a result of collaborative efforts by many individuals and organizations, including physicians, patients, Health Authorities, universities, industry, the World Health Organization, the Council for International Organizations of Medical Sciences, and the International Conference on Harmonisation. Biomedical informatics is rooted in technologically based methodologies and has evolved at the speed of computer technology...
November 29, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27912031/three-dimensional-reconstruction-of-preoperative-imaging-improves-surgical-success-in-laparoscopy
#4
Tobias Simpfendörfer, Ziyao Li, Claudia Gasch, Frederik Drosdzol, Markus Fangerau, Michael Müller, Lena Maier-Hein, Markus Hohenfellner, Dogu Teber
PURPOSE: To show the benefit of three-dimensional (3D) reconstructions of preoperative imaging for surgical performance. METHODS: A laparoscopic training environment with 15 hidden lymph nodes was designed. Three of them were marked with radiographic contrast agent and were only distinguishable from unmarked nodes via CT imaging. Thirty-six surgeons were divided into two groups. To group 1 the unprocessed CT data were shown. Group 2 was additionally shown a 3D reconstruction of the anatomy...
December 2, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27911868/design-and-implementation-of-a-mobile-system-for-lung-cancer-patient-follow-up-in-china-and-initial-report-of-the-ongoing-patient-registry
#5
Xiangyun Ye, Jia Wei, Ziming Li, Xiaomin Niu, Jiemin Wang, Yunqin Chen, Zongming Guo, Shun Lu
INTRODUCTION: Management of lung cancer remains a challenge. Although clinical and biological patient data are crucial for cancer research, these data may be missing from registries and clinical trials. Biobanks provide a source of high-quality biological material for clinical research; however, linking these samples to the corresponding patient and clinical data is technically challenging. We describe the mobile Lung Cancer Care system (mLCCare), a novel tool which integrates biological and clinical patient data into a single resource...
November 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/27911774/optically-transparent-semiconducting-polymer-nanonetwork-for-flexible-and-transparent-electronics
#6
Kilho Yu, Byoungwook Park, Geunjin Kim, Chang-Hyun Kim, Sungjun Park, Jehan Kim, Suhyun Jung, Soyeong Jeong, Sooncheol Kwon, Hongkyu Kang, Junghwan Kim, Myung-Han Yoon, Kwanghee Lee
Simultaneously achieving high optical transparency and excellent charge mobility in semiconducting polymers has presented a challenge for the application of these materials in future "flexible" and "transparent" electronics (FTEs). Here, by blending only a small amount (∼15 wt %) of a diketopyrrolopyrrole-based semiconducting polymer (DPP2T) into an inert polystyrene (PS) matrix, we introduce a polymer blend system that demonstrates both high field-effect transistor (FET) mobility and excellent optical transparency that approaches 100%...
November 22, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27911127/immediate-and-lasting-effects-of-a-thoracic-spine-manipulation-in-a-patient-with-signs-of-cervical-radiculopathy-and-upper-extremity-hyperalgesia-a-case-report
#7
Beth K Deschenes, Jason Zafereo
Patients with cervical radiculopathy (CR) may present with accompanying symptoms of hyperalgesia, allodynia, heaviness in the arm, and non-segmental pain that do not appear to be related to a peripheral spinal nerve. These findings may suggest the presence of central or autonomic nervous system involvement, requiring a modified management approach. The purpose of this case report is to describe the treatment of a patient with signs of CR and upper extremity (UE) hyperalgesia who had a significant decrease in her UE pain and hypersensitivity after a single thoracic spine manipulation (TSM)...
December 2, 2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27911118/effects-of-intense-pulsed-light-in-microstomia-in-patients-with-systemic-sclerosis-a-pilot-study
#8
Lisbeth Rosholm Comstedt, Åke Svensson, Roger Hesselstrand, Leena Lehti, Agneta Troilius Rubin
INTRODUCTION: The effects of IPL on collagen structures is well known in the treatment of photo damaged skin. OBJECTIVE: To investigate the effect of IPL on sclerotic skin by treating patients with microstomia due to systemic sclerosis. METHOD AND MATERIAL: 13 patients all with microstomia and systemic sclerosis was treated with IPL PR/VL applicator. They were treated in the perioral area 8 times with 3-4 weeks' interval and follow-up for 6 months...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27910723/powered-mobility-intervention-understanding-the-position-of-tool-use-learning-as-part-of-implementing-the-alp-tool
#9
Lisbeth Nilsson, Josephine Durkin
PURPOSE: To explore the knowledge necessary for adoption and implementation of the Assessment of Learning Powered mobility use (ALP) tool in different practice settings for both adults and children. To consult with a diverse population of professionals working with adults and children, in different countries and various settings; who were learning about or using the ALP tool, as part of exploring and implementing research findings. METHOD: Classical grounded theory with a rigorous comparative analysis of data from informants together with reflections on our own rich experiences of powered mobility practice and comparisons with the literature...
December 2, 2016: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/27909778/it-is-all-about-the-solvent-on-the-importance-of-the-mobile-phase-for-zic-hilic-glycopeptide-enrichment
#10
Kathirvel Alagesan, Sana Khan Khilji, Daniel Kolarich
Glycopeptide enrichment is a crucial step in glycoproteomics for which hydrophilic interaction chromatography (HILIC) has extensively been applied due to its low bias towards different glycan types. A systematic evaluation of applicable HILIC mobile phases on glycopeptide enrichment efficiency and selectivity is, to date, however, still lacking. Here, we present a novel, simplified technique for HILIC enrichment termed "Drop-HILIC", which was applied to systematically evaluate the mobile phase effect on ZIC-HILIC (zwitterionic type of hydrophilic interaction chromatography) glycopeptide enrichment...
December 1, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27909518/symptoms-in-atrial-fibrillation-a-contemporary-review-and-future-directions
#11
REVIEW
Steven T Heidt Bs, Anna Kratz PhD, Kayvan Najarian PhD, Afton L Hassett PsyD, Hakan Oral Md, Richard Gonzalez PhD, Brahmajee K Nallamothu Md Mph, Daniel Clauw Md, Hamid Ghanbari Md Mph
Atrial fibrillation (AF) is the most prevalent arrhythmia leading to hospital admissions in the United States. The majority of patients with AF report symptoms associated with this condition that can lead to a decrease in health related quality of life (HRQOL) and functional status. Therefore, along with reducing the risk of stroke and mortality, improvements in such symptoms are important therapeutic goals in the management of patients with AF. Our current understanding of how AF and symptoms are linked is hampered by the dominant assessment paradigm, where symptoms thought to be associated with AF are measured at a single point in time (frequently at a clinic visit)...
June 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27908978/potential-of-laboratory-execution-systems-less-to-simplify-the-application-of-business-process-management-systems-bpmss-in-laboratory-automation
#12
Sebastian Neubert, Bernd Göde, Xiangyu Gu, Norbert Stoll, Kerstin Thurow
Modern business process management (BPM) is increasingly interesting for laboratory automation. End-to-end workflow automation and improved top-level systems integration for information technology (IT) and automation systems are especially prominent objectives. With the ISO Standard Business Process Model and Notation (BPMN) 2.X, a system-independent and interdisciplinary accepted graphical process control notation is provided, allowing process analysis, while also being executable. The transfer of BPM solutions to structured laboratory automation places novel demands, for example, concerning the real-time-critical process and systems integration...
December 1, 2016: Journal of Laboratory Automation
https://www.readbyqxmd.com/read/27908844/quittr-the-design-of-a-video-game-to-support-smoking-cessation
#13
Ivan Bindoff, Kristy de Salas, Gregory Peterson, Tristan Ling, Ian Lewis, Lindsay Wells, Peter Gee, Stuart G Ferguson
BACKGROUND: Smoking is recognized as the largest, single, preventable cause of death and disease in the developed world. While the majority of smokers report wanting to quit, and many try each year, smokers find it difficult to maintain long-term abstinence. Behavioral support, such as education, advice, goal-setting, and encouragement, is known to be beneficial in improving the likelihood of succeeding in a quit attempt, but it remains difficult to effectively deliver this behavioral support and keep the patient engaged with the process for a sufficient duration...
December 1, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27906404/highly-efficient-and-stable-mos2-fets-with-reversible-n-doping-using-a-dehydrated-poly-vinyl-alcohol-coating
#14
César J Lockhart de la Rosa, Amirhasan Nourbakhsh, Markus Heyne, Inge Asselberghs, Cedric Huyghebaert, Iuliana Radu, Marc Heyns, Stefan De Gendt
Despite rapid progress in 2D molybdenum disulfide (MoS2) research in recent years, MoS2 field-effect transistors (FETs) still suffer from a high metal-to-MoS2 contact resistance and low intrinsic mobility, which are major hindrances to their future application. We report an efficient technique to dope thin-film MoS2 FETs using a poly(vinyl-alcohol) (PVA) polymeric coating. This results in a reduction of the contact resistance by up to 30% as well as a reduction in the channel resistance to 20 kΩ sq(-1). Using a dehydration process, we were able to effectively control the surface interactions between MoS2 and the more electropositive hydroxyl groups (-OH) of PVA, which provided a controllable and yet reversible increase in the charge carrier density to a value of 8...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27906071/are-digital-interventions-for-smoking-cessation-in-pregnancy-effective-a-systematic-review-protocol
#15
Sarah Ellen Griffiths, Katherine E Brown, Emily Anne Fulton, Ildiko Tombor, Felix Naughton
BACKGROUND: Behavioural support for smoking cessation in pregnancy can be effective; however, many pregnant women face barriers to seeking support to stop smoking. Some digital interventions have been found to be effective for smoking cessation in the general population and may be effective for supporting cessation in pregnancy due to their flexibility and the potential for personalisation. To date, there is limited evidence of the effectiveness of digital interventions for smoking cessation in pregnancy...
December 1, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27905970/a-feasibility-study-on-using-smartphones-to-conduct-short-version-verbal-autopsies-in-rural-china
#16
Jing Zhang, Rohina Joshi, Jixin Sun, Samantha R Rosenthal, Miao Tong, Cong Li, Rasika Rampatige, Meghan Mooney, Alan Lopez, Lijing L Yan
BACKGROUND: Currently there are two main sources of mortality data with cause of death assignments in China. Both sources-the Ministry of Health-Vital Registration system and the Chinese Disease Surveillance Point system-present their own challenges. A new approach to cause of death assignment is a smartphone-based shortened version of a verbal autopsy survey. This study evaluates the feasibility and acceptability of this new method conducted by township health care providers (THP) and village doctors (VD) in rural China, where a large proportion of deaths occur in homes and cause of death data are inaccurate or lacking...
August 20, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905259/regenerative-pharmacology-recent-developments-and-future-perspectives
#17
James Koudy Williams, Karl-Erik Andersson
This review focuses on the current status of research that utilizes the application of pharmacological sciences to accelerate, optimize and characterize the development, maturation and function of bioengineered and regenerating tissues. These regenerative pharmacologic approaches have been applied to diseases of the urogenital tract, the heart, the brain, the musculoskeletal system and diabetes. Approaches have included the use of growth factors (such as VEGF and chemokines (stromal-derived factor - CXCL12) to mobilize cell to the sights of tissue loss or damage...
December 1, 2016: Regenerative Medicine
https://www.readbyqxmd.com/read/27902942/a-simple-and-sensitive-liquid-chromatography-tandem-mass-spectrometry-method-for-trans-%C3%AE%C2%B5-viniferin-quantification-in-mouse-plasma-and-its-application-to-a-pharmacokinetic-study-in-mice
#18
Jiseon Kim, Jee Sun Min, Doyun Kim, Yu Fen Zheng, Karabasappa Mailar, Won Jun Choi, Choongho Lee, Soo Kyung Bae
In this study, a simple and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of trans-ε-viniferin in small volumes (10μl) of mouse plasma using chlorpropamide as an internal standard was developed and validated. Plasma samples were precipitated with acetonitrile and separated using an Eclipse Plus C18 column (100×4.6mm, 1.8-μm) with a mobile phase consisting of 0.1% formic acid in acetonitrile and 0.1% formic acid in water (60:40v/v) at a flow rate of 0.5ml/min...
November 24, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27901132/ligand-density-quantification-on-colloidal-inorganic-nanoparticles
#19
REVIEW
Ashley M Smith, Kathryn A Johnston, Scott E Crawford, Lauren E Marbella, Jill E Millstone
Colloidal inorganic nanoparticles are being used in an increasingly large number of applications ranging from biological imaging to television displays. In all cases, nanoparticle surface chemistry can significantly impact particle physical properties, processing, and performance. The first step in leveraging this tunability is to develop analytical approaches to describe surface chemical features. Some of the most basic descriptors of particle surface chemistry include the quantity, identity, and arrangement of ligands appended to the particle core...
November 30, 2016: Analyst
https://www.readbyqxmd.com/read/27900745/-the-effects-of-a-mobile-application-social-support-program-on-postpartum-perceived-stress-and-depression
#20
Hsuesh-Yu Cheng, Tsuey-Yuan Huang, Li-Yu Chien, Yu-Fen Cheng, Fen-Ju Chen
BACKGROUND: Postpartum depression is a common health problem for women following childbirth. Using effective social support to reduce postpartum depression has become an important issue. The current popularity of smartphones offers new possibilities for interventional methods. PURPOSE: To investigate the effects of mobile-application-based social support programs on perceived stress and postpartum depression in postpartum women. METHODS: The present study employs an experimental research design...
December 2016: Hu Li za Zhi the Journal of Nursing
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