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https://www.readbyqxmd.com/read/29334256/differential-content-of-secondary-metabolites-in-diploid-and-tetraploid-cytotypes-of-siegesbeckia-orientalis-l
#1
Saroj Kumar Pradhan, Raghbir Chand Gupta, Rajesh Kumar Goel
Siegesbeckia orientalis L. is an annual herb widely distributed throughout the world and has many medicinal properties. In Chinese traditional system, it is popularly known as Xi-Xian and used for its anti-inflammatory properties. In the present study, two cytotypes (diploid and tetraploid) have been investigated for their secondary metabolites. The different plant parts have been explored in terms of total phenolics, total flavonoids, DPPH radical scavenging acitivity and total antioxidant capacity. Out of different plant parts, leaves have the maximum amount of secondary metabolites and antioxidant potential...
January 15, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29328398/synergistic-antitumor-effect-of-brusatol-combined-with-cisplatin-on-colorectal-cancer-cells
#2
Hai-Ming Chen, Zheng-Quan Lai, Hui-Jun Liao, Jian-Hui Xie, Yan-Fang Xian, Yun-Long Chen, Siu-Po Ip, Zhi-Xiu Lin, Zi-Ren Su
Colorectal cancer (CRC) is a common and life‑threatening type of malignant cancer, which is associated with a high mortality rate. Cisplatin (CDDP) is a commonly used chemotherapy drug with significant side effects. Brusatol (BR) is one of the principal chemical compounds isolated from the Chinese herb Bruceae Fructus, which has been reported to markedly inhibit the proliferation of numerous cancer cell lines. The present study aimed to investigate the possible synergistic anticancer effects of CDDP combined with BR on CT‑26 cells, and to evaluate the underlying mechanisms of action...
January 9, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29327548/-research-of-tcm-synthetic-rehabilitation-on-the-recovery-of-wrist-joint-after-distal-radius-fractures
#3
Yong Zhao, Qing-Qing Dong, Wei-Kai Qin, An Yan, Kuan Zhang, Guo-Dong Zhao, Gang Wang, Jin-Chao Geng, Zhan-Feng Wang, Ze-Ming Lu
OBJECTIVE: To evaluate efficacy and advantages of the Traditional Chinese Medicine (TCM) synthetic rehabilitation therapy in the treatment of wrist dysfunction after distal radius fractures. METHODS: From May 2014 to October 2015, 72 patients with distal radius fracture meeting standards were treated using central randomization system for clinical research. All the patients were divided into two groups: 36 patients in test group and 36 in control group. Sixty-nine cases were finished treatment and followed up in the end...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29327395/effects-of-traditional-chinese-medicine-formula-on-ruminal-fermentation-enzyme-activities-and-nutrient-digestibility-of-beef-cattle
#4
Zhi Zhu, Zhen-Hui Song, Li-Ting Cao, Yong Wang, Wen-Zhang Zhou, Pei Zhou, Fu-Yuan Zuo
This study was conducted to evaluate effects of traditional Chinese medicine formula (TCMF) combined with several herbs on ruminal fermentation, enzyme activities and nutrient digestibility. Twenty finishing bulls were assigned to control or different TCMFs (Yufeisan-1, -2, -3; 2.5% dry matter (DM) in concentrate). Results showed that DM intake was higher (P < 0.05) in the Yufeisan-3 group than others. Compared to control, apparent digestibility of crude protein and neutral detergent fiber were increased (P < 0...
January 12, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29324310/25-hydroxyl-protopanaxatriol-protects-against-h2o2-induced-h9c2-cardiomyocytes-injury-via-pi3k-akt-pathway-and-apoptotic-protein-down-regulation
#5
Zhihao Wang, Guangyue Su, Zhiguo Zhang, Han Dong, Yuehui Wang, Huiying Zhao, Yuqing Zhao, Qi Sun
Oxidative stress injury and apoptosis are the main mechanisms of myocardial ischemia-reperfusion injury (MI/RI). Compounds with anti-oxidant properties can treat MI/RI. Therefore, identification of natural antioxidants such as herbs or botanical drugs is an ideal strategy to develop safe and effective anti-MI/RI drugs. Cardioprotective effects of Ginseng are well documented and are attributable to its anti-oxidant, anti-inflammatory, anti-tumorigenic, anti-arrhythmic, anti-ischemic properties. Ginseng monomer 20®-dammarane -3 beta,6 alpha,12 beta,20,25-pentol(25-hydroxyl-Protopanaxatriol,25-OH-PPT), a novel compound, which belongs to panaxatriol category, is extracted from the leaves and stem of ginseng...
January 8, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29322864/effects-of-danshen-tablets-on-pharmacokinetics-of-atorvastatin-calcium-in-rats-and-its-potential-mechanism
#6
Sen Sun, Rong Wang, Jie Fan, Guoqing Zhang, Hai Zhang
CONTEXT: Danshen tablets (DST), an effective traditional Chinese multi-herbal formula, are often combined with atorvastatin calcium (AC) for treating coronary heart disease in the clinic. OBJECTIVE: This study investigated the effects of DST on the pharmacokinetics of AC and the potential mechanism. MATERIALS AND METHODS: The pharmacokinetics of AC (1 mg/kg) with or without pretreatment of DST (100 mg/kg) were investigated using LC-MS/MS...
December 2018: Pharmaceutical Biology
https://www.readbyqxmd.com/read/29322587/growth-rings-in-roots-of-medicinal-perennial-dicotyledonous-herbs-from-temperate-and-subtropical-zones-in-china
#7
Shanshan Chu, Lingling Tan, Chanchan Liu, Huasheng Peng, Haiyan Duan, Luqi Huang
Growth years are closely related to the quality of Chinese medicinal materials, and they can provide a reliable basis for quality evaluation on crude drugs in accordance with the suitable growth years. Herbchronology, the numerical and pattern analysis of annual growth rings in herbaceous perennials, has emerged to be a recognized science that is applied in age determination of perennial forbs. Fifty medicinal species growing in temperate and subtropical zones of China were examined by microstructure observation to determine the presence of growth rings in the secondary root xylem of medicinal perennial dicotyledonous herbs...
January 11, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29322012/inhibition-of-aqueous-extracts-of-solanum-nigrum-aesn-on-oral-cancer-through-regulation-of-mitochondrial-fission
#8
Wu-Ching Uen, Bao-Hong Lee, Yeu-Ching Shi, She-Ching Wu, Chen-Jei Tai, Cheng-Jeng Tai
The present study is designed to investigate the anti-oral cancer properties of Solanum nigrum on oral squamous cell carcinoma. S. nigrum is a Chinese herb used for suppression of various cancers. However, the inhibition of S. nigrum on oral cancer is unclear. Therefore, human oral squamous cancer cells (SCC)-4 were used to evaluate the effect of aqueous extracts of S. nigrum (AESN) on cancer cell proliferation, cell cycle, mitochondrial function and apoptosis. The SCC-4 cells were treated by AESN to evaluate the inhibition of cell proliferation and mitochondrial function in vitro...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29321808/itraq-based-proteomic-analysis-to-identify-the-molecular-mechanism-of-zhibai-dihuang-granule-in-the-yin-deficiency-heat-syndrome-rats
#9
Chang-Ming Liu, Jing Chen, Su Yang, Ting-Ting Jiang, Zhong-Liang Chen, Hui-Hui Tu, Lian-Gen Mao, Yu-Ting Hu, Lin Gan, Zhong-Jie Li, Ji-Cheng Li
Background: Zhibai Dihuang Granule (ZDG) is a traditional Chinese medicine which has been used to treat Yin-deficiency-heat (YDH) syndrome for thousands of years in China. However, little work has been conducted to explore the molecular mechanism of ZDG in YDH syndrome, and the processes of YDH syndrome prevention and treatment have been developed slowly. The present study was aimed to explore the therapeutic mechanism of ZDG on YDH syndrome. Methods: The YDH syndrome rats were induced by hot Chinese herbs, then treated by ZDG orally for 1 week...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29321719/cancer-chemoprevention-and-therapy-using-chinese-herbal-medicine
#10
REVIEW
Lijing Jiao, Ling Bi, Yan Lu, Qin Wang, Yabin Gong, Jun Shi, Ling Xu
Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory properties against carcinogenesis, including CHM single-herb extracts, CHM-derived active components, and CHM formulas (the polyherbal combinations), which regulate JAK/STAT, MAPK, and NF-ҡB pathways. The present review aims to report the cancer-preventive effect of CHM with evidence from cell-line, animal, epidemiological, and clinical experiments...
2018: Biological Procedures Online
https://www.readbyqxmd.com/read/29321678/systems-pharmacology-analysis-of-synergy-of-tcm-an-example-using-saffron-formula
#11
Jianling Liu, Jingjing Liu, Fengxia Shen, Zonghui Qin, Meng Jiang, Jinglin Zhu, Zhenzhong Wang, Jun Zhou, Yingxue Fu, Xuetong Chen, Chao Huang, Wei Xiao, Chunli Zheng, Yonghua Wang
Traditional Chinese medicine (TCM) follows the principle of formulae, in which the pharmacological activity of a single herb can be enhanced or potentiated by addition of other herbs. Nevertheless, the involved synergy mechanisms in formulae remain unknown. Here, a systems-based method is proposed and applied to three representative Chinese medicines in compound saffron formula (CSF): two animal spices (Moschus, Beaver Castoreum), and one herb Crocus sativus which exert synergistic effects for cardiovascular diseases (CVDs)...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29318840/-application-of-remote-sensing-and-gis-in-study-of-suitability-distribution-of-swertia-mussotii-a-tibetan-medicine-in-sichuan-province
#12
Yong-Bo Dong, Yao Luo, Cong Zhu, Wen-Fu Peng, Xin-Liang Xu, Qing-Mao Fang
Swertia mussotii is a kind of rare medicinal materials, the relevant researches are mainly concentrated on its medicinal efficacy and medicinal value till now, researches of adaptive distribution by applying remote sensing and GIS are relatively less. This study is to analyze the adaptive distribution of S.mussotii in Sichuan province by applying remote sensing and GIS technology, and provide scientific basis for the protection and development of wild resources, artificial cultivation and adjustment of Chinese medicine industrial distribution in Sichuan province...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318836/-study-of-extracting-peucedanum-praeruptorum-planted-area-in-ningguo-of-anhui-province-based-on-multi-source-and-multi-phase-image
#13
Ting-Ting Shi, Xiao-Bo Zhang, Ke Zhang, Lan-Ping Guo, Lu-Qi Huang
The herbs used as the material for traditional Chinese medicine are always planted in the mountainous area where the natural environment is suitable. As the mountain terrain is complex and the distribution of planting plots is scattered, the traditional survey method is difficult to obtain accurate planting area. It is of great significance to provide decision support for the conservation and utilization of traditional Chinese medicine resources by studying the method of extraction of Chinese herbal medicine planting area based on remote sensing and realizing the dynamic monitoring and reserve estimation of Chinese herbal medicines...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318835/-study-on-extraction-method-of-panax-notoginseng-plots-in-wenshan-of-yunnan-province-based-on-decision-tree-model
#14
Ting-Ting Shi, Xiao-Bo Zhang, Lan-Ping Guo, Lu-Qi Huang
The herbs used as the material for traditional Chinese medicine are always planted in the mountainous area where the natural environment is suitable. As the mountain terrain is complex and the distribution of planting plots is scattered, the traditional survey method is difficult to obtain accurate planting area. It is of great significance to provide decision support for the conservation and utilization of traditional Chinese medicine resources by studying the method of extraction of Chinese herbal medicine planting area based on remote sensing and realizing the dynamic monitoring and reserve estimation of Chinese herbal medicines...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318827/-design-and-implementation-of-supply-security-monitoring-and-analysis-system-for-chinese-patent-medicines-supply-in-national-essential-medicines
#15
Hui Wang, Xiao-Bo Zhang, Lu-Qi Huang, Lan-Ping Guo, Ling Wang, Yu-Ping Zhao, Guang Yang
The supply of Chinese patent medicine is influenced by the price of raw materials (Chinese herbal medicines) and the stock of resources. On the one hand, raw material prices show cyclical volatility or even irreversible soaring, making the price of Chinese patent medicine is not stable or even the highest cost of hanging upside down. On the other hand, due to lack of resources or disable some of the proprietary Chinese medicine was forced to stop production. Based on the micro-service architecture and Redis cluster deployment Based on the micro-service architecture and Redis cluster deployment, the supply security monitoring and analysis system for Chinese patent medicines in national essential medicines has realized the dynamic monitoring and intelligence warning of herbs and Chinese patent medicine by connecting and integrating the database of Chinese medicine resources, the dynamic monitoring system of traditional Chinese medicine resources and the basic medicine database of Chinese patent medicine...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318822/-design-and-implementation-of-data-reporting-system-for-chinese-materia-medica-resources-survey
#16
Hui Wang, Xiao-Bo Zhang, Xiao-Guang Ge, Zhi-Xian Jing, Ling Wang, Yu-Ping Zhao, Lan-Ping Guo, Lu-Qi Huang
The collection, summary and sharing of all kinds of survey data are one of the main tasks and achievements in the national census of Chinese materia medica resources organized and implemented by the State Administration of Traditional Chinese Medicine. It is a key link in the implementation of the national census of Chinese materia medica resources. Based on the client / server architecture, the data reporting system for Chinese materia medica resources survey has been established for reporting system application model of geospatial data service based on Web implementation, through the SOA framework, to achieve the data collection summary of the seven aspects of the local data configuration, data reporting, data verification, data reporting, PDA data import and export, APP data import, track instrument data import...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318820/-detection-and-analysis-of-effect-of-geographical-environmental-factors-on-spatial-distribution-of-artemisinic-acid-in-artemisia-annua
#17
Ting-Ting Shi, Xiao-Bo Zhang, Lan-Ping Guo, Hui Wang, Zhi-Xian Jing, Lu-Qi Huang
Dao-di herbs are preferred by long-term clinical application of Chinese medicine, they are produced in a specific area and affected by the specific production and processing methods. Dao-di herbs have a high reputation, compared with other regions produced by the same kind of herbs with good quality, good efficacy and stable quality characteristics. Geo-herbal is a unique concept that has been formed by the history of Chinese civilization for thousands of years and the history of Chinese medicine. According to the definition of geo-herbal, it can be seen that there are some differences in the quality and efficacy of the same kind of medicinal herbs in different regions, and there is some similarity in the specific area...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318819/-analysis-of-spatial-distribution-of-artemisinin-in-artemisia-annua-in-china
#18
Xiao-Bo Zhang, Lan-Ping Guo, Zhi-Dong Qiu, Xiao-Bo Qu, Hui Wang, Zhi-Xian Jing, Lu-Qi Huang
Geo-herbals are preferred by long-term clinical application of Chinese medicine, they are produced in a specific area and affected by the specific production and processing methods. Geo-herbals have a high reputation, compared with other regions produced by the same kind of herbs with good quality, efficacy and stable quality characteristics. Geo-herbal is a unique concept that has been formed by the history of Chinese civilization for thousands of years and the history of Chinese medicine. According to the definition of geo-herbal, it can be seen that there are some differences in the quality and efficacy of the same kind of medicinal herbs in different regions, and there is some similarity in the specific area...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318817/-application-of-image-recognition-technology-in-census-of-national-traditional-chinese-medicine-resources
#19
Xiao-Bo Zhang, Xiao-Guang Ge, Yan Jin, Ting-Ting Shi, Hui Wang, Meng Li, Zhi-Xian Jing, Lan-Ping Guo, Lu-Qi Huang
With the development of computer and image processing technology, image recognition technology has been applied to the national medicine resources census work at all stages.Among them: ①In the preparatory work, in order to establish a unified library of traditional Chinese medicine resources, using text recognition technology based on paper materials, be the assistant in the digitalization of various categories related to Chinese medicine resources; to determine the representative area and plots of the survey from each census team, based on the satellite remote sensing image and vegetation map and other basic data, using remote sensing image classification and other technical methods to assist in determining the key investigation area...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29316822/beneficial-anti-inflammatory-effect-of-paeonol-self-microemulsion-loaded-colon-specific-capsules-on-experimental-ulcerative-colitis-rats
#20
Shiyu Zong, Yiqiong Pu, Suyun Li, Benliang Xu, Yong Zhang, Tong Zhang, Bing Wang
Paeonol, as the main phenolic compound isolated from the Chinese herbs, has been confirmed to present anti-inflammatory effects on ulcerative colitis (UC) in our previous study. However, its poor solubility has hindered its development of being a favourable pharmaceutical product in treating colon diseases. In this study, we prepared the colon-specific delivery system (Pae-SME-CSC) with paeonol-loaded self-microemulsion (Pae-SMEDDS), and evaluated its in vitro and in vivo properties, especially the anti-inflammatory effects on UC rats...
January 9, 2018: Artificial Cells, Nanomedicine, and Biotechnology
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