keyword
MENU ▼
Read by QxMD icon Read
search

Bioreactance

keyword
https://www.readbyqxmd.com/read/29315862/toxic-reactive-oxygen-species-enhanced-synergistic-combination-therapy-by-self-assembled-metal-phenolic-network-nanoparticles
#1
Yunlu Dai, Zhen Yang, Siyuan Cheng, Zhongliang Wang, Ruili Zhang, Guizhi Zhu, Zhantong Wang, Bryant C Yung, Rui Tian, Orit Jacobson, Can Xu, Qianqian Ni, Jibin Song, Xiaolian Sun, Gang Niu, Xiaoyuan Chen
Engineering functional nanomaterials with high therapeutic efficacy and minimum side effects has increasingly become a promising strategy for cancer treatment. Herein, a reactive oxygen species (ROS) enhanced combination chemotherapy platform is designed via a biocompatible metal-polyphenol networks self-assembly process by encapsulating doxorubicin (DOX) and platinum prodrugs in nanoparticles. Both DOX and platinum drugs can activate nicotinamide adenine dinucleotide phosphate oxidases, generating superoxide radicals (O2•- )...
January 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29300470/co-variation-between-distribution-of-microbial-communities-and-biological-metabolization-of-organics-in-urban-sewer-systems
#2
Pengkang Jin, Xuan Shi, Guangxi Sun, Lei Yang, Yixiao Cai, Xiaochang C Wang
Distribution characteristics and biodiversity of microbial communities were studied in a 1200-m pilot sewer system. Results showed that the dominant microorganisms, fermentation bacteria (FB), hydrogen-producing acetogen (HPA), sulphate-reducing bacteria (SRB) and methanogenic archaea (MA) changed significantly along the sewer systems, from start to the end. The distribution of the functional microorganisms could induce substrate transformation and lead to the accumulation of micromolecular organics (i.e., acetic acid, propionic acid and amino acid)...
January 4, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29300454/in-situ-caging-of-biomolecules-in-graphene-hybrids-for-light-modulated-bioactivity
#3
Gong Cheng, Xiaohui Han, Si-Jie Hao, Merisa Nisic, Si-Yang Zheng
Remote and noninvasive modulation of protein activity is essential for applications in biotechnology and medicine. Optical control has emerged as the most attractive approach owing to its high spatial and temporal resolutions; however, it is challenging to engineer light responsive proteins. In this work, a near-infrared (NIR) light-responsive graphene-silica-trypsin (GST) nanoreactor is developed for modulating the bioactivity of trypsin molecules. Biomolecules are spatially confined and protected in the rationally designed compartment architecture, which not only reduces the possible interference but also boosts the bioreaction efficiency...
January 4, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29247380/utilizing-mass-spectrometry-imaging-to-map-the-thyroid-hormones-triiodothyronine-and-thyroxine-in-xenopus-tropicalis-tadpoles
#4
Naoko Goto-Inoue, Tomohiko Sato, Mizuki Morisasa, Akihiko Kashiwagi, Keiko Kashiwagi, Yuki Sugiura, Eiji Sugiyama, Makoto Suematsu, Tsukasa Mori
Thyroid hormones are not only responsible for thermogenesis and energy metabolism in animals, but also have an important role in cell differentiation and development. Amphibian metamorphosis provides an excellent model for studying the remodeling of the body. This metamorphic organ remodeling is induced by thyroid hormones, and a larval body is thus converted into an adult one. The matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry (MS) imaging technology is expected to be a suitable tool for investigating small bioreactive molecules...
December 15, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29230392/non-invasive-monitoring-of-cardiac-output-in-critical-care-medicine
#5
REVIEW
Lee S Nguyen, Pierre Squara
Critically ill patients require close hemodynamic monitoring to titrate treatment on a regular basis. It allows administering fluid with parsimony and adjusting inotropes and vasoactive drugs when necessary. Although invasive monitoring is considered as the reference method, non-invasive monitoring presents the obvious advantage of being associated with fewer complications, at the expanse of accuracy, precision, and step-response change. A great many methods and devices are now used over the world, and this article focuses on several of them, providing with a brief review of related underlying physical principles and validation articles analysis...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29193874/a-factorial-design-to-identify-process-parameters-affecting-whole-mechanically-disrupted-rat-pancreata-in-a-perfusion-bioreactor
#6
Jamie Sharp, Tim Wgm Spitters, Patrick Vermette
Few studies report whole pancreatic tissue culture, as it is a difficult task using traditional culture methods. Here, a factorial design was used to investigate the singular and combinational effects of flow, dissolved oxygen concentration (D.O.) and pulsation on whole mechanically-disrupted rat pancreata in a perfusion bioreactor. Whole rat pancreata were cultured for 72h under defined bioreactor process conditions. Secreted insulin was measured and histological (haematoxylin and eosin (H&E)) as well as immunofluorescent insulin staining were performed and quantified...
November 29, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/29073545/in-vitro-structure-specific-zn-ii-induced-adipogenesis-and-structure-function-bioreactivity-correlations
#7
E Halevas, O Tsave, M Yavropoulou, J G Yovos, A Hatzidimitriou, V Psycharis, A Salifoglou
The advent of Zn(II) metallodrugs in metabolic syndrome pathologies generates a strong challenge toward synthetic endeavors targeting well-defined, atoxic and biologically active binary/ternary species of Zn(II). Proper formulation of that metal ion's coordination sphere sets the stage for construction of appropriately configured Schiff ligands based on tromethamine and variably modified vanillin core components. The arising Schiff ligands react with Zn(II) in a defined stoichiometry, thereby delivering new binary Zn(II)-L species with defined physicochemical properties...
September 6, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28957705/aptamer-based-hydrogel-barcodes-for-the-capture-and-detection-of-multiple-types-of-pathogenic-bacteria
#8
Yueshuang Xu, Huan Wang, Chengxin Luan, Yuxiao Liu, Baoan Chen, Yuanjin Zhao
Rapid and sensitive diagnosing hematological infections based on the separation and detection of pathogenic bacteria in the patient's blood is a significant challenge. To address this, we herein present a new barcodes technology that can simultaneously capture and detect multiple types of pathogenic bacteria from a complex sample. The barcodes are poly (ethylene glycol) (PEG) hydrogel inverse opal particles with characteristic reflection peak codes that remain stable during bacteria capture on their surfaces...
September 20, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28939490/uptake-and-bioreactivity-of-charged-chitosan-coated-superparamagnetic-nanoparticles-as-promising-contrast-agents-for-magnetic-resonance-imaging
#9
Gabriela Kania, Magdalena Sternak, Agnieszka Jasztal, Stefan Chlopicki, Agnieszka Błażejczyk, Anna Nasulewicz-Goldeman, Joanna Wietrzyk, Krzysztof Jasiński, Tomasz Skórka, Szczepan Zapotoczny, Maria Nowakowska
Bioreactivity of superparamagnetic iron oxide nanoparticles (SPION) coated with thin layers of either cationic or anionic chitosan derivatives and serving as contrast agents in magnetic resonance imaging (MRI) was studied in vivo using BALB/c mouse model. Synthesized dual-modal fluorescing SPION were tracked in time using both fluorescent imaging and MRI. Although SPION started to be excreted by kidneys relatively shortly after administration they were uptaken by liver enhancing MRI contrast even up to 7 days...
September 19, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28884187/enantioselective-recognition-of-an-isomeric-ligand-by-a-biomolecule-mechanistic-insights-into-static-and-dynamic-enantiomeric-behavior-and-structural-flexibility
#10
Wei Peng, Fei Ding
Chirality is a ubiquitous basic attribute of nature, which inseparably relates to the life activity of living organisms. However, enantiomeric differences have still failed to arouse enough attention during the biological evaluation and practical application of chiral substances, and this poses a large threat to human health. In the current study, we explore the enantioselective biorecognition of a chiral compound by an asymmetric biomolecule, and then decipher the molecular basis of such a biological phenomenon on the static and, in particular, the dynamic scale...
October 24, 2017: Molecular BioSystems
https://www.readbyqxmd.com/read/28871609/the-origin-of-soil-organic-matter-controls-its-composition-and-bioreactivity-across-a-mesic-boreal-forest-latitudinal-gradient
#11
Lukas Kohl, Michael Philben, Kate A Edwards, Frances A Podrebarac, Jamie Warren, Susan E Ziegler
Warmer climates have been associated with reduced bioreactivity of soil organic matter (SOM) typically attributed to increased diagenesis; the combined biological and physiochemical transformation of SOM. Additionally, cross site studies have indicated that ecosystem regime shifts, associated with long-term climate warming, can affect SOM properties through changes in vegetation and plant litter production thereby altering the composition of soil inputs. The relative importance of these two controls, diagenesis and inputs, on SOM properties as ecosystems experience climate warming, however, remains poorly understood...
September 4, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28866204/a-facile-novel-fluorocarbon-copolymer-solution-coating-process-for-improving-platelet-compatibility-of-titanium
#12
Sophia Chao-Wei Huang, Chi-Hui Cheng, Yun Chiu, Yi-Ching Lin, Jui-Che Lin
Titanium (Ti) and its alloys possess mechanical properties that are desirable in many biomedical applications compared to other metals. Furthermore, the native metal oxide layer that prevents further oxidation is also known to be biocompatible. However, clinical findings have shown that titanium and its alloys are prone to adverse bioreactions such as platelet adhesion and activation which could lead to thrombogenic complications. It has been found that surfaces modified with fluorocarbons could reduce the degree of both platelet adhesion and activation...
November 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28863996/improvement-of-fermentation-performance-of-gluconobacter-oxydans-by-combination-of-enhanced-oxygen-mass-transfer-in-compressed-oxygen-supplied-sealed-system-and-cell-recycle-technique
#13
Xin Zhou, Xuelian Zhou, Yong Xu
Oxygen supply for microbial cultures is often identified as a limiting factor for aerobic fermentation. Through implementation of an integrated oxygen control strategy, the high oxygen mass transfer rate satisfied cellular metabolic demands. Gluconobacter oxydans NL71 fermentation of xylose to xylonic acid was improved remarkably. Finally, the productivity of xylonic acid from xylose by biooxidation was markedly increased to 32.5±3.1g/L/h compared to production levels using conventional laboratory-scale bioreactors...
November 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28805054/a-scalable-field-study-protocol-and-rationale-for-passive-ambient-air-sampling-a-spatial-phytosampling-for-leaf-data-collection
#14
Tonny J Oyana, Slawomir M Lomnicki, Chuqi Guo, Stephania A Cormier
Stable, bioreactive, radicals known as environmentally persistent free radicals (EPFRs) have been found to exist on the surface of airborne PM2.5. These EPFRs have been found to form during many combustion processes, are present in vehicular exhaust, and persist in the environment for weeks and biological systems for up to 12 h. To measure EPFRs in PM samples, high volume samplers are required and measurements are less representative of community exposure; therefore, we developed a novel spatial phytosampling methodology to study the spatial patterns of EPFR concentrations using plants...
August 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28642078/experimental-tests-on-commercial-sweet-product-residue-spr-as-a-suitable-feed-for-anaerobic-bioenergy-h2-ch4-production
#15
Andrea C Luongo Malavè, Debora Fino, Carlos E Gómez Camacho, Bernardo Ruggeri
Food stores can find themselves in the position of having to dispose of different types of products, such as snacks, confectionery, prepackaged food, drinks and others, Sweet Product Residue (SPR), which presents a great opportunity to produce energy through Anaerobic Digestion (AD), due to its high sugar, carbohidrate and fat contents. In order to valorise SPR, this paper takes into consideration the all necessary treatments; owing the fact that the refuses are constitute by an organic part and packaging (plastic, paper and their combinations), a pretreatment able to remove the latter is necessary...
June 19, 2017: Waste Management
https://www.readbyqxmd.com/read/28574213/comparison-of-cardiac-output-estimates-by-bioreactance-and-inert-gas-rebreathing-methods-during-cardiopulmonary-exercise-testing
#16
Nduka C Okwose, Shakir Chowdhury, David Houghton, Michael I Trenell, Christopher Eggett, Matthew Bates, Guy A MacGowan, Djordje G Jakovljevic
PURPOSE: This study assessed the agreement between cardiac output estimated by inert gas rebreathing and bioreactance methods at rest and during exercise. METHODS: Haemodynamic measurements were assessed in 20 healthy individuals (11 females, nine males; aged 32 ± 10 years) using inert gas rebreathing and bioreactance methods. Gas exchange and haemodynamic data were measured simultaneously under rest and different stages (i.e. 30, 60, 90, 120, 150 and 180 W) of progressive graded cardiopulmonary exercise stress testing using a bicycle ergometer...
June 2, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28525778/inferior-vena-cava-collapsibility-detects-fluid-responsiveness-among-spontaneously-breathing-critically-ill-patients
#17
Keith A Corl, Naomi R George, Justin Romanoff, Andrew T Levinson, Darin B Chheng, Roland C Merchant, Mitchell M Levy, Anthony M Napoli
PURPOSE: Measurement of inferior vena cava collapsibility (cIVC) by point-of-care ultrasound (POCUS) has been proposed as a viable, non-invasive means of assessing fluid responsiveness. We aimed to determine the ability of cIVC to identify patients who will respond to additional intravenous fluid (IVF) administration among spontaneously breathing critically-ill patients. METHODS: Prospective observational trial of spontaneously breathing critically-ill patients...
October 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28482223/biological-effects-of-%C3%AE-adrenergic-phentolamine-on-erythrocyte-hemeprotein-molecular-insights-from-biorecognition-behavior-protein-dynamics-and-flexibility
#18
Wei Peng, Fei Ding, Yu-Kui Peng, Yong Xie
Phentolamine is one of the most representative nonselective α-adrenoreceptor blocking agents, which have been proved to be owned various pharmacological actions. Unfortunately, whether erythrocytes in the veins intervene in biological behaviors of such drug are largely obscured. With the aid of multiple biophysical techniques, this scenario was to detailed explore the potential biorecognition between phentolamine and the hemeprotein in the cytosol of erythrocytes, and the influences of dynamic characters of protein during the bioreaction...
June 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28441030/measuring-cardiac-output-during-cardiopulmonary-exercise-testing
#19
Carlo Vignati, Gaia Cattadori
Cardiac output is a key parameter in the assessment of cardiac function, and its measurement is fundamental to the diagnosis, treatment, and prognostic evaluation of all heart diseases. Until recently, cardiac output determination during exercise had been only possible through invasive methods, which were not practical in the clinical setting. Because [Formula: see text]o2 is cardiac output times arteriovenous content difference, evaluation of cardiac output is usually included in its measurement. Because of the difficulty of directly measuring peak exercise cardiac output, indirect surrogate parameters have been proposed, but with only modest clinical usefulness...
July 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28419043/confirmation-of-sexual-dimorphisms-in-metal-hypersensitivity-and-joint-pain-following-total-joint-arthroplasty-commentary-on-an-article-by-marco-s-caicedo-phd-et-al-females-with-unexplained-joint-pain-following-total-joint-arthroplasty-exhibit-a-higher-rate
#20
keyword
keyword
1472
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"