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https://www.readbyqxmd.com/read/28965619/transcatheter-aortic-valve-replacement-in-patients-with-aortic-stenosis-and-mitral-regurgitation
#1
Kreton Mavromatis, Vinod H Thourani, Amanda Stebbins, Sreekanth Vemulapalli, Chandan Devireddy, Robert A Guyton, Roland Matsouaka, Nima Ghasemzadeh, Peter C Block, Bradley G Leshnower, James P Stewart, John S Rumsfeld, Stamatios Lerakis, Vasilis Babaliaros
BACKGROUND: Many patients undergoing transcatheter aortic valve replacement (TAVR) for aortic stenosis also have significant mitral regurgitation (MR). We sought to understand the association of concomitant MR with TAVR clinical outcomes, as well changes in MR following TAVR. METHODS: Patients who underwent TAVR in the US Transcatheter Valve Therapy Registry from January 3, 2012, to December 31, 2013, were studied, with longer-term clinical outcomes from Center for Medicare Services data...
September 29, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28867369/-oral-anticoagulation-in-atrial-fibrillation-what-is-the-guideline-for-using-new-drugs
#2
J A Ibáñez Pérez de Viñaspre, J Gómez Bitrian, R Royo Hernández, M de Azúa Jiménez, C Marco López, L Urieta González
OBJECTIVE: To assess whether there are differences between atrial fibrillation (AF) patients initiating new direct-acting oral anticoagulants (DOAC) therapy and vitamin K antagonist (VKA) therapy in an emergency service. METHODS: Descriptive, observational, prospective study. We enrolled patients with AF who were visited in a hospital emergency service over one year. RESULTS: This study included 492 patients with AF, and 189 subjects received anticoagulant therapy, 104 with VKA (55%), and 85 with DOAC (45%)...
August 31, 2017: Semergen
https://www.readbyqxmd.com/read/28845230/screening-for-valve-disease-in-patients-with-hyperprolactinaemia-disorders-prescribed-cabergoline-a-service-evaluation-and-literature-review
#3
REVIEW
David Gamble, Rachel Fairley, Roderick Harvey, Colin Farman, Nathan Cantley, Stephen J Leslie
OBJECTIVES: The indication for screening for valvular heart disease in patients taking cabergoline is based on evidence from patients with Parkinson's disease on high-dose medication. However, current patients take much lower doses for indications such as hyperprolactinaemia disorders. Contemporary guidelines for echocardiogram monitoring in patients taking cabergoline are conflicting. This study aimed to review current clinical practice in our area regarding echocardiographic screening and to review the literature examining the evidence of valvular heart disease in patients taking lower dose cabergoline...
July 2017: Therapeutic Advances in Drug Safety
https://www.readbyqxmd.com/read/28837458/early-lessons-on-bundled-payment-at-an-academic-medical-center
#4
Lindsay E Jubelt, Keith S Goldfeld, Saul B Blecker, Wei-Yi Chung, John A Bendo, Joseph A Bosco, Thomas J Errico, Anthony K Frempong-Boadu, Richard Iorio, James D Slover, Leora I Horwitz
INTRODUCTION: Orthopaedic care is shifting to alternative payment models. We examined whether New York University Langone Medical Center achieved savings under the Centers for Medicare and Medicaid Services Bundled Payments for Care Improvement initiative. METHODS: This study was a difference-in-differences study of Medicare fee-for-service patients hospitalized from April 2011 to June 2012 and October 2013 to December 2014 for lower extremity joint arthroplasty, cardiac valve procedures, or spine surgery (intervention groups), or for congestive heart failure, major bowel procedures, medical peripheral vascular disorders, medical noninfectious orthopaedic care, or stroke (control group)...
September 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28820030/epidemiology-of-cardiovascular-disease-in-the-united-states-implications-for-the-perfusion-profession-a-2017-update
#5
Joseph J Sistino, David C Fitzgerald
INTRODUCTION: By analyzing epidemiological trends in cardiovascular disease (CVD), key stakeholders can make informed decisions on the future of disease burden and treatment. Accordingly, the cardiovascular perfusion community would benefit from data that would help predict future professional resource utilization. METHODS: In 2003, the changes in the number of hospital discharges for CVD from 1990 to 2000 were published, based on data from the National Center for Health Statistics (NCHS)...
September 2017: Perfusion
https://www.readbyqxmd.com/read/28728722/transcatheter-aortic-valve-replacement-a-review
#6
REVIEW
John H Braxton, Kelly S Rasmussen, Milind S Shah
Patients with inoperable, high-risk, and intermediate-risk aortic stenosis can now be treated with transcatheter aortic valve replacement. Centers for Medicare and Medicaid Services and the Food and Drug Administration selectively choose centers based on experience and require a collaborative, multidisciplinary team approach in the treatment and decision making for these patients. The work-up has been streamlined. Gated multislice computed tomography angiogram has emerged as the gold standard for assessment of valve anatomy and sizing of the transcatheter heart valve...
August 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28698799/adults-with-repaired-tetralogy-low-mortality-but-high-morbidity-up-to-middle-age
#7
Mark Dennis, Ben Moore, Irina Kotchetkova, Lynne Pressley, Rachael Cordina, David S Celermajer
OBJECTIVE: Survival of patients with repaired tetralogy of Fallot (rToF) into young adulthood is very good. Concerns exist, however, over long-term morbidity and mortality as these subjects reach middle age. We aimed to assess survival and the prevalence of complications in patients with rToF seen in our Adult Congenital Heart Disease (ACHD) service. METHODS: One hundred and sixty-eight consecutive patients with 'simple rToF', aged over 16 years, followed up at our tertiary-level ACHD service in Sydney, Australia since 2000, were included...
2017: Open Heart
https://www.readbyqxmd.com/read/28577686/atrial-fibrillation-incrementally-increases-dementia-risk-across-all-chads2-and-cha2ds2vasc-strata-in-patients-receiving-long-term-warfarin
#8
Kevin G Graves, Heidi T May, Victoria Jacobs, Tami L Bair, Scott M Stevens, Scott C Woller, Brian G Crandall, Michael J Cutler, John D Day, Charles Mallender, Jeffrey S Osborn, J Peter Weiss, T Jared Bunch
BACKGROUND: Patients with atrial fibrillation (AF) are at higher risk for developing dementia. Warfarin is a common therapy for the prevention of thromboembolism in AF, valve replacement, and thrombosis patients. The extent to which AF itself increases dementia risk remains unknown. METHODS: A total 6030 patients with no history of dementia and chronically anticoagulated with warfarin were studied. Warfarin management was provided through a Clinical Pharmacy Anticoagulation Service...
June 2017: American Heart Journal
https://www.readbyqxmd.com/read/28541591/infective-endocarditis-cinderella-in-cardiology
#9
Amit Kaura, Dorota Dworakowska, Rafal Dworakowski
Infective endocarditis (IE) is uncommon, however, the incidence is on the rise [1]. Despite improvements in its management, infective endocarditis (IE) is associated with significant short- and long-term morbidity and mortality [2]. A definitive diagnosis of IE may be challenging and is often delayed due to the highly variable and non-specific symptoms at patient presentation, alongside limited availability of specialist services [3]. In addition to IE remaining a diagnostic challenge, the decisions about the treatment modality (medical vs surgical) and the timing of potential valve surgery are demanding, despite established national and international guidelines [4]...
May 25, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28504229/kazakhstan-coronary-and-structural-heart-interventions-from-2010-to-2015
#10
Orazbek S Sakhov, Murat E Kuzhukeyev, Almat T Kodasbayev, Tolegen Zh Egemberdiev, Salim F Berkinbayev, Bekbolat K Zholdin, Serik A Alimbaev, Sholpan B Zhangelova, Rustam A Rakhimov, Daniyar I Makhanov, Yersyn T Sabitov, Dauren A Teleuov, Ruslan K Baisebenov, Arystan M Kuzhukeyev
This paper presents data on the nascence and development of the interventional cardiology service in Kazakhstan. It provides details of the structure of the Kazakhstan interventional cardiology service, staff training, the number of coronary and structural heart interventions for the period of 2010-2015, as well as the peculiarities of the capitation payment method. The number of coronary interventions is increasing year by year, though the number of intracoronary imaging techniques and intracoronary flow/pressure techniques remains inadequate...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28395636/ttk-chitra-tilting-disc-heart-valve-model-tc2-an-assessment-of-fatigue-life-and-durability
#11
N N Subhash, Adathala Rajeev, Sreedharan Sujesh, C V Muraleedharan
Average age group of heart valve replacement in India and most of the Third World countries is below 30 years. Hence, the valve for such patients need to be designed to have a service life of 50 years or more which corresponds to 2000 million cycles of operation. The purpose of this study was to assess the structural performance of the TTK Chitra tilting disc heart valve model TC2 and thereby address its durability. The TC2 model tilting disc heart valves were assessed to evaluate the risks connected with potential structural failure modes...
April 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28343443/lacosamide-induced-recurrent-ventricular-tachycardia-in-the-acute-care-setting
#12
Theodore J Berei, Matthew P Lillyblad, Adrian K Almquist
Lacosamide is a new-generation antiepileptic drug (AED) most commonly used adjunctively in the setting of partial-onset seizures refractory to traditional therapy. We describe the first case report, to our knowledge, of a patient who developed recurrent, sustained ventricular tachycardia with multiple administrations of lacosamide in an acute setting. A 70-year-old woman with a history significant for valvular heart disease was admitted to the inpatient cardiology service for worsening heart failure. On hospital day 7, she received a bioprosthetic aortic valve...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28247199/cost-effectiveness-of-genotype-guided-warfarin-dosing-in-patients-with-mechanical-heart-valve-replacement-under-the-fee-for-service-system
#13
Dong-Jin Kim, Ho-Sook Kim, Minkyung Oh, Eun-Young Kim, Jae-Gook Shin
BACKGROUND: Although studies assessing the cost effectiveness of genotype-guided warfarin dosing for the management of atrial fibrillation, deep vein thrombosis, and pulmonary embolism have been reported, no publications have addressed genotype-guided warfarin therapy in mechanical heart valve replacement (MHVR) patients or genotype-guided warfarin therapy under the fee-for-service (FFS) insurance system. OBJECTIVE: The aim of this study was to evaluate the cost effectiveness of genotype-guided warfarin dosing in patients with MHVR under the FFS system from the Korea healthcare sector perspective...
February 28, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28238245/rheumatic-fever-and-rheumatic-heart-disease-collaboration-patterns-and-research-core-topics
#14
Alejandro Salinas, Gregorio González, Jose Manuel Ramos
BACKGROUND: Rheumatic fever and rheumatic heart disease (RHD) are important health problems in developing countries. The study aim was to provide a review and content analysis of the scientific literature on rheumatic fever and RHD over a 70-year period. METHODS: Medline was employed via the online PubMed service of the US National Library of Medicine, to search for all documents containing the MeSH terms 'rheumatic fever' or 'rheumatic heart disease' between January 1945 and December 2013...
September 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28131996/cohort-profile-prevalence-of-valvular-heart-disease-in-community-patients-with-suspected-heart-failure-in-uk
#15
Anna Marciniak, Keli Glover, Rajan Sharma
PURPOSE: The aim of this study was to evaluate the proportion of suspected heart failure patients with significant valvular heart disease. Early diagnosis of valve disease is essential as delay can limit treatment and negatively affect prognosis for undiagnosed patients. The prevalence of unsuspected valve disease in the community is uncertain. PARTICIPANTS: We prospectively evaluated 79 043 patients, between 2001 and 2011, who were referred to a community open access echocardiography service for suspected heart failure...
January 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28076623/low-cost-simulator-for-heart-surgery-training
#16
Roberto Rocha E Silva, Artur Lourenção, Maxim Goncharov, Fabio B Jatene
Objective: Introduce the low-cost and easy to purchase simulator without biological material so that any institution may promote extensive cardiovascular surgery training both in a hospital setting and at home without large budgets. Methods: A transparent plastic box is placed in a wooden frame, which is held by the edges using elastic bands, with the bottom turned upwards, where an oval opening is made, "simulating" a thoracotomy. For basic exercises in the aorta, the model presented by our service in the 2015 Brazilian Congress of Cardiovascular Surgery: a silicone ice tray, where one can train to make aortic purse-string suture, aortotomy, aortorrhaphy and proximal and distal anastomoses...
November 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27832844/incidence-predictors-and-outcomes-of-permanent%C3%A2-pacemaker-implantation-following-transcatheter-aortic-valve%C3%A2-replacement-analysis-from-the-u-s-society-of-thoracic-surgeons-american-college-of-cardiology-tvt-registry
#17
COMPARATIVE STUDY
Opeyemi O Fadahunsi, Abiola Olowoyeye, Anene Ukaigwe, Zhuokai Li, Amit N Vora, Sreekanth Vemulapalli, Eric Elgin, Anthony Donato
OBJECTIVES: The purpose of this study was to evaluate the incidence, predictors, and clinical outcomes of permanent pacemaker (PPM) implantation following transcatheter aortic valve replacement (TAVR). BACKGROUND: Conduction abnormalities leading to PPM implantation are common complications following TAVR. Whether PPM placement can be predicted or is associated with adverse outcomes is unclear. METHODS: A retrospective cohort study of patients undergoing TAVR in the United States at 229 sites between November 2011 and September 2014 was performed using the Society of Thoracic Surgeons/American College of Cardiology TVT Registry and the Centers for Medicare and Medicaid Services database...
November 14, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27697799/audit-of-a-tertiary-heart-failure-outpatient-service-to-assess-compliance-with-nice-guidelines
#18
Kaushik Guha, Christopher J Allen, Sumir Chawla, Hayley Pryse-Hawkins, Laura Fallon, Vicki Chambers, Ali Vazir, Alex R Lyon, Martin R Cowie, Rakesh Sharma
The National Institute for Health and Care Excellence (NICE) updated its guidelines for chronic heart failure (HF) in 2010. This re-audit assessed interim improvement as compared with an audit in 2011. Patients with HF (preserved and reduced ejection fraction) attending a tertiary cardiac centre over a 2-year period (January 2013-December 2014) were audited. The data collected included demographics, HF aetiology, medications, clinical parameters and cardiac rehabilitation. In total, 513 patients were audited...
October 2016: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/27629092/why-are-acute-ischemic-stroke-patients-not-receiving-iv-tpa-results-from-a-national-registry
#19
Steven R Messé, Pooja Khatri, Mathew J Reeves, Eric E Smith, Jeffrey L Saver, Deepak L Bhatt, Maria V Grau-Sepulveda, Margueritte Cox, Eric D Peterson, Gregg C Fonarow, Lee H Schwamm
OBJECTIVE: To determine patient and hospital characteristics associated with not providing IV tissue plasminogen activator (tPA) to eligible patients with acute ischemic stroke (AIS) in clinical practice. METHODS: We performed a retrospective cohort study of patients with AIS arriving within 2 hours of onset to hospitals participating in Get With The Guidelines-Stroke without documented contraindications to IV tPA from April 2003 through December 2011, comparing those who received tPA to those who did not...
October 11, 2016: Neurology
https://www.readbyqxmd.com/read/27583536/german-heart-surgery-report-2015-the-annual-updated-registry-of-the-german-society-for-thoracic-and-cardiovascular-surgery
#20
Andreas Beckmann, Anne-Katrin Funkat, Jana Lewandowski, Michael Frie, Markus Ernst, Khosro Hekmat, Wolfgang Schiller, Jan F Gummert, Armin Welz
On the basis of a long-standing voluntary registry, which was founded by the German Society for Thoracic and Cardiovascular Surgery (GSTCVS), well-defined data of all heart, thoracic, and vascular surgery procedures performed in 78 German heart surgery departments during 2015 are analyzed. In 2015, a total of 103,967 heart surgery procedures (implantable cardioverter defibrillator, pacemaker, and extracardiac procedures without ECC excluded) were submitted to the database. Approximately 14.8% of the patients were at least 80 years old, resulting in an increase of 0...
September 2016: Thoracic and Cardiovascular Surgeon
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