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Heart valve implantation

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https://www.readbyqxmd.com/read/29688916/gastrointestinal-bleeding-with-left-ventricular-assist-devices-lvad-locating-the-leak-and-identifying-outcomes
#1
Sarah Malik, Shahbaz A Malik, Laura L Ulmer, Lokesh K Jha, Michael S Strupp, Eugenia Raichlin, Elizabeth R Lyden, Alexander T Hewlett
BACKGROUND AND GOALS: Gastrointestinal bleeding (GIB) is a significant complication following left ventricular assist device (LVAD) implantation. We evaluated the incidence, predictors, endoscopic findings, and outcomes of GIB in LVAD recipients. STUDY: Retrospective review of 205 adult patients undergoing HeartMate II LVAD implantation from January 2012 to June 2016. Patients were reviewed and separated into GIB (n=57; 28%) and non-GIB (n=148; 72%) groups. RESULTS: Median time to GIB was 55 (range, 3 to 730) days...
April 23, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29688568/-aortic-stenosis-is-a-common-disease-which-requires-individualized-treatment
#2
Vendela Berglund, Gustav Mattsson, Peter Magnusson
Aortic stenosis is the most common valvular heart disease and the prevalence increases with age. Common symptoms include dyspnea, angina, and syncope. Echocardiography is a cornerstone in diagnosis of aortic stenosis. Severe aortic stenosis is defined as peak aortic jet velocity ≥4 m/s, a mean transvalvular gradient ≥40 mmHg, and/or an aortic valve area <1.0 cm2. The two-year mortality in patients with symptomatic aortic stenosis is 50 percent without intervention. The only efficient treatment is intervention, either open heart valve replacement or percutaneous transcatheter implantation of an aortic valve prosthesis (TAVI), which both provide symptomatic relief and improved survival...
April 23, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29688322/conduction-dynamics-after-transcatheter-aortic-valve-implantation-and-implications-for-permanent-pacemaker-implantation-and-early-discharge-the-conduct-study
#3
Lennart van Gils, Sara Baart, Herbert Kroon, Zouhair Rahhab, Nahid El Faquir, Ramón Rodriguez Olivares, Yaar Aga, Anne-Marie Maugenest, Dominic A Theuns, Eric Boersma, Tamas Szili Torok, Peter P De Jaegere, Nicolas M Van Mieghem
Aims: To correlate dynamics in electrical conduction after transcatheter aortic valve implantation (TAVI) with need for permanent pacemaker implantation (PPM) and assess implications for early discharge. Methods and results: Daily electrocardiograms after TAVI were analysed for rhythm and conduction times and were correlated with PPM. Transcatheter aortic valve implantation was performed in 291 consecutive patients with three contemporary transcatheter heart valve designs: Medtronic CoreValve (n = 111), Edwards Sapien XT (n = 29) and Sapien 3 (n = 72), and Boston Lotus (n = 79)...
April 20, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29688192/-modern-polyurethanes-in-cardiovascular-surgery
#4
A A Gostev, P P Laktionov, A A Karpenko
Currently, there is great clinical demand for synthetic tissue-engineered cardiovascular prostheses with good long-term patency. Polyurethanes belong to the class of polymers with excellent bio- and hemocompatibility. They are known to possess good mechanical properties, but are prone to processes of degradation in conditions of functioning in living organisms. Attempts at solving this problem have resulted in the development of various new subclasses of polyurethanes such as thermoplastic polyether polyurethanes, polyurethanes with a silicone segment, polycarbonate polyurethanes and nanocomposite polyurethanes...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29688174/matched-comparison-of-next-and-early-generation-balloon-expandable-transcatheter-heart-valve-implantations-in-failed-surgical-aortic-bioprostheses
#5
Moritz Seiffert, Hendrik Treede, Joachim Schofer, Axel Linke, Jochen Woehrle, Hardy Baumbach, Julinda Mehilli, Vinayak Bapat, Matheus Simonato, Thomas Walther, Mathias Kullmer, Peter Boekstegers, Stephan Ensminger, Thomas Kurz, Hélène Eltchaninoff, Ardawan Rastan, Nicolas Werner, Arend de Weger, Christian Frerker, Bernward Lauer, Olivier Muller, Brian Whisenant, Arun Thukkani, Giora Weisz, Danny Dvir
AIMS: Transcatheter valve-in-valve implantation (VinV) is established for the treatment of degenerated surgical bioprostheses in patients at high operative risk. Our aim was to report on the first large assessment of VinV with next generation balloon-expandable transcatheter heart valves. METHODS AND RESULTS: 514 patients after SAPIEN XT or SAPIEN 3 VinV were analyzed using an inverse probability of treatment weighting. Standardized clinical and hemodynamic outcomes were compared and core laboratory evaluation of implantation depth was performed...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29680865/comparison-of-midterm-outcomes-of-transcatheter-aortic-valve-implantation-in-patients-with-and-without-previous-coronary-artery-bypass-grafting
#6
Hideyuki Kawashima, Yusuke Watanabe, Ken Kozuma, Akihisa Kataoka, Makoto Nakashima, Hirofumi Hioki, Fukuko Nagura, Yugo Nara, Shinichi Shirai, Norio Tada, Motoharu Araki, Toru Naganuma, Futoshi Yamanaka, Hiroshi Ueno, Minoru Tabata, Kazuki Mizutani, Akihiro Higashimori, Kensuke Takagi, Masanori Yamamoto, Kentaro Hayashida
The midterm safety and feasibility of transcatheter aortic valve implantation (TAVI) for patients with a history of coronary artery bypass graft (CABG) and high operative risk are unclear. This study compared the midterm outcomes of patients undergoing TAVI with or without previous CABG surgery. Between October 2013 and July 2016, 1,613 patients underwent TAVI according to the Optimized CathEter vAlvular iNtervention (OCEAN)-TAVI registry (previous CABG: n = 120; no previous CABG: n = 1493). The propensity score comprised the variables of the Society of Thoracic Surgeons Score, previous myocardial infarction, peripheral artery disease, chronic kidney disease > stage 2 (estimated glomerular filtration rate < 60 mL/min/1...
April 21, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29675905/transient-left-anterior-and-septal-fascicular-blocks-after-self-expandable-percutaneous-transcatheter-aortic-valve-implantation
#7
Andrés R Pérez-Riera, Raimundo Barbosa-Barros, Mariana F Cabral de Oliveira, Rodrigo Daminello-Raimundo, Luiz C de Abreu, Kjell Nikus
Transcatheter aortic valve implantation (TAVI) is indicated in severe symptomatic aortic stenosis, when there is intermediate-high surgical risk, or a condition considered inoperable, as in the case of "porcelain aorta" that could turn clamping or cannulation of the ascending aorta hazardous in open-heart surgery. Among the complications of this less invasive procedure, intraventricular conduction disorders subsequent to the procedure stand out. TAVI causes worsening of intraventricular dromotropic disorders in more than 75% of the cases, with the presence of preexisting right bundle branch block and first-degree atrioventricular block, deep prosthesis implant, male gender, size of the aortic annulus smaller than the prosthesis, and porcelain aorta being predictive of requirement for permanent pacemaker implant...
April 19, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29673504/usefulness-of-tricuspid-annular-diameter-to-predict-late-right-sided-heart-failure-in-patients-with-left-ventricular-assist-device
#8
Koki Nakanishi, Shunichi Homma, Jiho Han, Hiroo Takayama, Paolo C Colombo, Melana Yuzefpolskaya, Arthur R Garan, Maryjane A Farr, Paul Kurlansky, Marco R Di Tullio, Yoshifumi Naka, Koji Takeda
Although late-onset right-sided heart failure is recognized as a clinical problem in the treatment of patients with left ventricular assist devices (LVADs), the mechanism and predictors are unknown. Tricuspid valve (TV) deformation leads to the restriction of the leaflet motion and decreased coaptation, resulting in a functional tricuspid regurgitation that may act as a surrogate marker of late right-sided heart failure. This study aimed to investigate the association of preoperative TV deformation (annulus dilatation and leaflet tethering) with late right-sided heart failure development after continuous-flow LVAD implantation...
March 28, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29666072/left-ventricular-assist-device-inflow-cannula-angle-and-thrombosis-risk
#9
Venkat Keshav Chivukula, Jennifer A Beckman, Anthony R Prisco, Todd Dardas, Shin Lin, Jason W Smith, Nahush A Mokadam, Alberto Aliseda, Claudius Mahr
BACKGROUND: As heart failure prevalence continues to increase in the setting of a static donor supply, left ventricular assist device (LVAD) therapy for end-stage heart failure continues to grow. Anecdotal evidence suggests that malalignment of the LVAD inflow cannula may increase thrombosis risk, but this effect has not been explored mechanistically or quantified statistically. Our objective is to elucidate the impact of surgical angulation of the inflow cannula on thrombogenicity. METHODS AND RESULTS: Unsteady computational fluid dynamics is used in conjunction with computational modeling and virtual surgery to model flow through the left ventricle for 5 different inflow cannula angulations...
April 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29664732/fibrous-composite-material-for-textile-heart-valve-design-in-vitro-assessment
#10
Amna Amri, Gaetan Laroche, Nabil Chakfe, Frederic Heim
With over 150,000 implantations performed over the world, transcatheter aortic valve replacement (TAVR) has become a surgical technique, which largely competes with open surgery valve replacement for an increasing number of patients. The success of the procedure favors the research toward synthetic valve leaflet materials as an alternative to biological tissues, whose durability remains unknown. In particular, fibrous constructions have recently proven to be durable in vivo over a 6-month period of time in animal sheep models...
April 17, 2018: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/29659801/long-term-performance-of-homografts-versus-stented-bioprosthetic-valves-in-the-pulmonary-position-in-patients-aged-10-20-years
#11
Douglas Bell, Sudesh Prabhu, Kim S Betts, Yilin Chen, Dorothy Radford, Chris Whight, Cameron Ward, Homayoun Jalali, Prem Venugopal, Nelson Alphonso
OBJECTIVES: We aimed to compare the long-term performance of pulmonary homografts and stented bioprosthetic valves in the pulmonary position in patients aged 10-20 years. METHODS: Between January 1995 and December 2015, 188 patients aged 10-20 years undergoing pulmonary valve replacement were identified retrospectively from hospital databases in both congenital cardiac centres in Brisbane. Valve performance was evaluated using previously described standard criteria...
April 11, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29657239/application-of-a-fresh-decellularized-pulmonary-allograft-for-pulmonary-valve-replacement-in-japan
#12
Hideto Ozawa, Takayoshi Ueno, Masaki Taira, Koichi Toda, Toru Kuratani, Yoshiki Sawa
BACKGROUND: Tissue engineering has advanced the technique of decellularization of the heart valve. The valve is reseeded with the patient's own cells after implantation with suppression of immunologic reactions. The same advantage has been reported for fresh decellularized heart valves, and more than 10 years of excellent outcomes have been achieved. We began performing such heart valve implantations in 2013 as part of a clinical study at Osaka University. We report our evaluation of the safety and efficacy of heart valve implantation...
April 14, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29656120/systemic-inflammatory-response-syndromes-in-the-era-of-interventional-cardiology
#13
REVIEW
Riccardo Gorla, Raimund Erbel, Kim A Eagle, Eduardo Bossone
Systemic inflammatory response syndrome (SIRS), initially reported after cardiovascular surgery, has been described after various interventional cardiology procedures, including endovascular/thoracic aortic repair (EVAR/TEVAR), implantation of heart rhythm devices, percutaneous coronary intervention (PCI), electrophysiology procedures (EP), and transcatheter aortic valve implantation (TAVI). In these settings, a comprehensive understanding of the triggers, pathogenesis as well as a common diagnostic/therapeutic algorithm is lacking and will be discussed in this review...
April 12, 2018: Vascular Pharmacology
https://www.readbyqxmd.com/read/29655822/clinical-spectrum-and-management-of-heart-failure-in-hypertrophic-cardiomyopathy
#14
REVIEW
Barry J Maron, Ethan J Rowin, James E Udelson, Martin S Maron
Heart failure (HF), characterized by excessive exertional dyspnea, is a common complication within the broad clinical spectrum of hypertrophic cardiomyopathy (HCM). HF has become an increasingly prominent management issue with the reduction in sudden deaths due to use of implantable defibrillators in this disease. Exertional dyspnea ranges in severity from mild to severe (New York Heart Association functional classes II to IV) and not uncommonly becomes refractory to medical management, leading to progressive disability, but largely in the absence of pulmonary congestion and volume overload requiring hospitalization...
April 5, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29652895/complications-after-transcatheter-aortic-valve-implantation-using-transfemoral-and-transapical-approach-in-general-anaesthesia
#15
Fabian Würschinger, Sigrid Wittmann, Sophia Goldfuß, Nina Zech, Kurt Debl, Michael Hilker, Bernhard M Graf, York A Zausig
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure used to treat degenerative heart valve disease. The implantation requires a highly specific and interdisciplinary management approach. Currently, TAVI is performed with the patient under local or general anaesthesia. METHODS: This study was a retrospective analysis of all TAVI procedures performed at the University Hospital of Regensburg between January 2009 and July 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29630054/technique-and-patient-selection-criteria-of-right-anterior-mini-thoracotomy-for-minimal-access-aortic-valve-replacement
#16
Reza Tavakoli, Pascal Leprince, Max Gassmann, Peiman Jamshidi, Nassrin Yamani, Julien Amour, Guillaume Lebreton
Aortic valve stenosis has become the most prevalent valvular heart disease in developed countries, and is due to the aging of these populations. The incidence of the pathology increases with growing age after 65 years. Conventional surgical aortic valve replacement through median sternotomy has been the gold standard of patient care for symptomatic aortic valve stenosis. However, as the risk profile of patients worsens, other therapeutic strategies have been introduced in an attempt to maintain the excellent results obtained by the established surgical treatment...
March 26, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29629921/assessment-of-cardiac-thrombosis-in-patients-with-left-ventricular-assist-device-using-multidetector-cardiac-computed-tomography
#17
Chukwuemeka A Obi, Nicholas Chan, Monica G Rizkalla, John N Makaryus
: A 79-year-old man with nonischemic cardiomyopathy who underwent left ventricular assist device HeartMate II and automated implantable cardioverter defibrillator placement presented with recurrent refractory sustained ventricular tachycardia, elevated lactate dehydrogenase, and low haptoglobin. Echocardiography demonstrated no thrombosis; cardiac computed tomography showed patent inflow and outflow cannulas while detecting an irregularly shaped mass adherent to the left coronary cusp of the aortic valve, suggesting a thrombus...
April 7, 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29629555/transcatheter-valve-with-a-hollow-balloon-for-aortic-valve-insufficiency
#18
Jacques Scherman, Braden van Breda, Harish Appa, Carel Heerden, Chima Ofoegbu, Deon Bezuidenhout, Peter Zilla
During the past decade transcatheter aortic valve implantation (TAVI) has revolutionized our approach to heart valve disease. Although largely applied to patients with calcific aortic valve stenosis, there is an unmet clinical need to also treat patients with aortic valve insufficiency in patients with non-calcific aortic valve disorders. The following Techno-College tutorial demonstrates our pre-clinical experience with a novel non-occlusive, self-homing TAVI system, developed with Strait Access Technologies, that we hope will improve outcomes for treatment of non-calcific aortic valve insufficiency...
February 26, 2018: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/29627180/transatrial-implantation-of-a-transcatheter-heart-valve-for-severe-mitral-annular-calcification
#19
Fabien Praz, Omar K Khalique, Raymond Lee, Ramesh Veeragandham, Hyde Russell, Mayra Guerrero, Ashequl M Islam, David W Deaton, Tsuyoshi Kaneko, Susheel K Kodali, Martin B Leon, Vinayak Bapat, Hiroo Takayama, Michael A Borger, Isaac George
OBJECTIVE: To assess the outcomes of transatrial implantation of a transcatheter heart valve (THV) for the treatment of mitral valve disease with severe mitral annular calcification (MAC). METHODS: Implantation of a balloon-expandable THV was performed on cardiopulmonary bypass via left atrial exposure in patients considered at risk for left ventricular outflow tract obstruction. The anterior mitral valve leaflet was systematically resected and pledgeted sutures were placed to enhance stability and reduce paravalvular leak...
March 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29626939/the-3m-approach-to-cardiovascular-infections-multimodality-multitracers-and-multidisciplinary
#20
REVIEW
Martina Sollini, Raffaella Berchiolli, Roberto C Delgado Bolton, Alexia Rossi, Margarita Kirienko, Roberto Boni, Elena Lazzeri, Riemer Slart, Paola Anna Erba
Cardiovascular infections are associated with high morbidity and mortality. Early diagnosis is crucial for adequate patient management, as early treatment improves the prognosis. The diagnosis cannot be made on the basis of a single symptom, sign, or diagnostic test. Rather, the diagnosis requires a multidisciplinary discussion in addition to the integration of clinical signs, microbiology data, and imaging data. The application of multimodality imaging, including molecular imaging techniques, has improved the sensitivity to detect infections involving heart valves and vessels and implanted cardiovascular devices while also allowing for early detection of septic emboli and metastatic infections before these become clinically apparent...
May 2018: Seminars in Nuclear Medicine
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