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Heart valve implantation

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https://www.readbyqxmd.com/read/29221741/balloon-expandable-transaortic-transcatheter-aortic-valve-implantation-with-or-without-predilation
#1
Nikolaos Bonaros, Markus Kofler, Derk Frank, Riccardo Cocchieri, Dariusz Jagielak, Marco Aiello, Joel Lapeze, Mika Laine, Sidney Chocron, Douglas Muir, Walter Eichinger, Matthias Thielmann, Louis Labrousse, Vinayak Bapat, Kjell Arne Rein, Jean-Philippe Verhoye, Gino Gerosa, Hardy Baumbach, Cornelia Deutsch, Peter Bramlage, Martin Thoenes, Mauro Romano
OBJECTIVE: It has been reported that balloon aortic valvuloplasty immediately before transfemoral or transapical transcatheter aortic valve implantation has mostly little to no clinical value. We aimed to provide data on the need for balloon aortic valvuloplasty in patients undergoing transaortic transcatheter aortic valve implantation. METHODS: Patients undergoing transaortic transcatheter aortic valve implantation with the Edwards SAPIEN XT (Nyon, Switzerland) or 3 transcatheter heart valve were prospectively included at 18 sites across Europe...
November 2, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29217244/intraoperative-transesophageal-and-postoperative-transthoracic-echocardiographic-evaluation-of-a-mechanical-heart-valve-prosthesis-implanted-at-aortic-position
#2
Saravana Babu, Rupa Sreedhar, Shrinivas V Gadhinglajkar, Prasanta Kumar Dash, Subin Sukesan, Vivek Pillai, Varghese T Panicker, Lovhale Pravin Shriram, Neelam Aggarwal
OBJECTIVE: The aims of this study were to evaluate the intraoperative transesophageal echocardiographic (iTEE) characteristics and Doppler flow profile of aortic Chitra heart valve prosthesis (CHVP) under stable hemodynamic and loading conditions, and to compare and correlate the iTEE data with the postoperative transthoracic echocardiography (TTE) data obtained at 48 hours (TTE1) and 3 months (TTE2) after the surgery. DESIGN: Prospective, observational study. SETTING: University-level tertiary referral hospital...
September 6, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29217006/incidence-prognostic-impact-and%C3%A2-predictive-factors-of-readmission-for-heart-failure-after-transcatheter-aortic-valve-replacement
#3
Eric Durand, Maxime Doutriaux, Nicolas Bettinger, Christophe Tron, Charles Fauvel, Fabrice Bauer, Jean-Nicolas Dacher, Najime Bouhzam, Pierre-Yves Litzler, Alain Cribier, Hélène Eltchaninoff
OBJECTIVES: The aim of this study was to assess the incidence, prognostic impact, and predictive factors of readmission for congestive heart failure (CHF) in patients with severe aortic stenosis treated by transcatheter aortic valve replacement (TAVR). BACKGROUND: TAVR is indicated in patients with severe symptomatic aortic stenosis in whom surgery is considered high risk or is contraindicated. Readmission for CHF after TAVR remains a challenge, and data on prognostic and predictive factors are lacking...
December 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29216666/-cardiac-rehabilitation
#4
Bernhard Schwaab
Physical training, psychosocial intervention, nutrition counselling and optimisation of secondary preventive medication to reduce morbidity and mortality of the disease as well as the reintegration into social life and return to work are equivalent goals of cardiac rehabilitation. This requires multifactorial intervention by a multidisciplinary team. In Germany, cardiac rehabilitation starting early after an index event could demonstrate a significant reduction of total mortality, myocardial infarction and hospitalisation during a follow-up of 1-2 years in 5 controlled cohort studies including 12 556 patients after myocardial infarction and CABG surgery...
December 7, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/29211226/implantation-of-short-term-and-long-term-right-ventricular-assist-devices
#5
Christiano Castello Branco Caldeira, Regimar Carla Machado, Debora Castello Branco Caldeira
The last decade has seen considerable growth in the use of left ventricular assist devices (LVAD), in end-phase heart failure treatment. The indications, contraindications and implantation techniques are well-defined. However, information about mechanical support for right ventricular failure is lacking. The aim of this communication is to present alternative techniques for implantation of short- and longterm right ventricular assist devices. Implanting the device in the right atrium has certain advantages when compared with the right ventricle...
September 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29209786/prognostic-value-of-preprocedural-6-min-walk-test-in-patients-undergoing-transcatheter-mitral-valve-repair-insights-from-the-german-transcatheter-mitral-valve-interventions-registry
#6
Jakob Ledwoch, Jennifer Franke, Edith Lubos, Peter Boekstegers, Miriam Puls, Taoufik Ouarrak, Stephan von Bardeleben, Christian Butter, Joachim Schofer, Ralf Zahn, Hüsseyin Ince, Jochen Senges, Horst Sievert
AIMS: The 6-min walk test (6 MWT) has been established as an important tool for functional assessment in heart failure patients. However, its prognostic impact on the outcome in subjects with mitral regurgitation undergoing transcatheter mitral valve repair is unknown. METHODS: This present work represents a sub-analysis of the German, prospective, multicenter, Transcatheter Mitral Valve Interventions (TRAMI) registry. Of the main study cohort (n = 828) 326 patients underwent 6 MWT prior to the procedure...
December 5, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29207365/thirty-day-outcomes-in-100-consecutive-patients-undergoing-transfemoral-aortic-valve-replacement-with-the-portico-valve-on-an-all-comer-basis
#7
Silvia Mas-Peiro, Mariuca Vasa-Nicotera, Helge Weiler, Nestoras Papadopoulos, Roberta De Rosa, Andreas M Zeiher, Stephan Fichtlscherer
OBJECTIVES: Transcatheter heart valves such as the self-expandable Portico valve (St. Jude Medical) are being developed to overcome limitations of first-generation devices. Since clinical experience with this valve is still limited in a real-world setting, we investigated its use on an all-comer basis. METHODS: Between October 2015 and October 2016, a total of 100 consecutive patients assessed for transcatheter aortic valve replacement (TAVR) and found suitable for the Portico valve were included...
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29191508/in-vivo-performance-of-freeze-dried-decellularized-pulmonary-heart-valve-allo-and-xenografts-orthotopically-implanted-into-juvenile-sheep
#8
Tobias Goecke, Karolina Theodoridis, Igor Tudorache, Anatol Ciubotaru, Serghei Cebotari, Robert Ramm, Klaus Höffler, Samir Sarikouch, Andrés Vásquez-Rivera, Axel Haverich, Willem F Wolkers, Andres Hilfiker
The decellularization of biological tissues decreases immunogenicity, allows repopulation with cells, and may lead to improved long-term performance after implantation. Freeze drying these tissues would ensure off-the-shelf availability, save storage costs, and facilitates easy transport. This study evaluates the in vivo performance of freeze-dried decellularized heart valves in juvenile sheep. TritonX-100 and sodium dodecylsulfate decellularized ovine and porcine pulmonary valves (PV) were freeze-dried in a lyoprotectant sucrose solution...
November 27, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29190355/trends-in-practice-and-outcomes-from-2011-to-2015-for-surgical-aortic-valve-replacement-an-update-from-the-german-aortic-valve-registry-on-42%C3%A2-776-patients
#9
Buntaro Fujita, Stephan Ensminger, Timm Bauer, Helge Möllmann, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Elke Schäfer, Christian W Hamm, Friedrich W Mohr, Hugo A Katus, Wolfgang Harringer, Thomas Walther, Christian Frerker
OBJECTIVES: Surgical aortic valve replacement (sAVR) is coming under close scrutiny with the recent upswing in the use of less invasive approaches. The aim of this analysis was to identify current trends in patient selection, procedural characteristics and outcomes after sAVR in Germany. METHODS: We analysed data from 42 776 patients included in the German Aortic Valve Registry who underwent sAVR with and without coronary artery bypass surgery (CABG) between 2011 and 2015...
November 27, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29188357/-management-of-valvular-heart-disease-esc-eacts-guidelines-2017
#10
REVIEW
M Haude
After 5 years the European Society of Cardiology and the European Association for Cardio-Thoracic Surgery have released an update on the guidelines for the management of valvular heart diseases. In recent years published results of randomized trials in patients with aortic valve stenosis have resulted in updated recommendations for catheter-based prosthesis implantation (TAVI), which is now extended to patients presenting without a low risk for conventional surgical valve replacement. In mitral or tricuspid valvular disease, the recommendations for catheter-based therapies are less strong because of a lack of supportive scientific data...
December 2017: Herz
https://www.readbyqxmd.com/read/29186380/impact-of-t-cell-mediated-immune-response-on-xenogeneic-heart-valve-transplantation-short-term-success-and-mid-term-failure
#11
Anna C Biermann, Julia Marzi, Eva Brauchle, Maria Schneider, Angela Kornberger, Sherif Abdelaziz, Julian L Wichmann, Christophe T Arendt, Eike Nagel, Kelvin G M Brockbank, Martina Seifert, Katja Schenke-Layland, Ulrich A Stock
OBJECTIVES: Allogeneic frozen cryopreserved heart valves (allografts or homografts) are commonly used in clinical practice. A major obstacle for their application is the limited availability in particular for paediatrics. Allogeneic large animal studies revealed that alternative ice-free cryopreservation (IFC) results in better matrix preservation and reduced immunogenicity. The objective of this study was to evaluate xenogeneic (porcine) compared with allogeneic (ovine) IFC heart valves in a large animal study...
November 27, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29185181/efficacy-and-safety-of-transcatheter-aortic-valve-implantation-with-edwards-sapien-3-and-xt-in-smaller-asian-anatomy
#12
Makoto Nakashima, Yusuke Watanabe, Hirofumi Hioki, Yugo Nara, Fukuko Nagura, Naoyoshi Hosogoe, Hideyuki Kawashima, Akihisa Kataoka, Shuji Otsuki, Kumiko Konno, Hiroyuki Kyono, Naoyuki Yokoyama, Ken Kozuma
We aimed to compare the efficacy and safety of transcatheter aortic valve implantation (TAVI) using Edwards SAPIEN 3 (S3) valve and SAPIEN XT) in smaller anatomy. The new generation S3 TAVI device has been used worldwide; however, its efficacy and safety in smaller Asian anatomy remain unknown. Between February 2014 and March 2017, 166 consecutive patients (S3, 54; XT, 112) were treated with balloon-expandable TAVI in a single center and their outcomes were analyzed. Median patient age was 85 (range: 81-88) years and mean body surface area was 1...
November 28, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/29182083/an-implantable-extracardiac-soft-robotic-device-for-the-failing-heart-mechanical-coupling-and-synchronization
#13
Christopher J Payne, Isaac Wamala, Colette Abah, Thomas Thalhofer, Mossab Saeed, Daniel Bautista-Salinas, Markus A Horvath, Nikolay V Vasilyev, Ellen T Roche, Frank A Pigula, Conor J Walsh
Soft robotic devices have significant potential for medical device applications that warrant safe synergistic interaction with humans. This article describes the optimization of an implantable soft robotic system for heart failure whereby soft actuators wrapped around the ventricles are programmed to contract and relax in synchrony with the beating heart. Elastic elements integrated into the soft actuators provide recoiling function so as to aid refilling during the diastolic phase of the cardiac cycle. Improved synchronization with the biological system is achieved by incorporating the native ventricular pressure into the control system to trigger assistance and synchronize the device with the heart...
September 2017: Soft Robotics
https://www.readbyqxmd.com/read/29181891/fluid-structure-interaction-of-a-pulsatile-flow-with-an-aortic-valve-model-a-combined-experimental-and-numerical-study
#14
J Sigüenza, D Pott, S Mendez, S J Sonntag, T A S Kaufmann, U Steinseifer, F Nicoud
The complex fluid-structure interaction problem associated with the flow of blood through a heart valve with flexible leaflets is investigated both experimentally and numerically. In the experimental test rig, a pulse duplicator generates a pulsatile flow through a biomimetic rigid aortic root where a model of aortic valve with polymer flexible leaflets is implanted. High-speed recordings of the leaflets motion and Particle Image Velocimetry measurements were performed together to investigate the valve kinematics and the dynamics of the flow...
November 27, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29181740/impact-of-mitral-valve-intervention-with-left-ventricular-assist-device-implantation-on-postoperative-outcomes-and-morphologic-change
#15
Hiroki Hata, Tomoyuki Fujita, Hatsue Ishibashi-Ueda, Kensuke Kuroda, Osamu Seguchi, Yorihiko Matsumoto, Masanobu Yanase, Takuma Sato, Seiko Nakajima, Norihide Fukushima, Junjiro Kobayashi
Although mitral regurgitation (MR) is prevalent in patients with end-stage heart failure, the impact of mitral valve (MV) surgery on outcomes after left ventricular assist device (LVAD) implantation and morphologic changes of MV remains unclear. We retrospectively reviewed 74 patients who underwent LVAD implantation as a bridge to transplant. Of these, 11 (15%) underwent MV repair concomitant with or prior to LVAD implantation, while 27 patients with preoperative significant (moderate or greater) MR did not undergo concomitant MV surgery...
November 27, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29177686/preclinical-animal-study-of-the-nipro-ventricular-assist-device-for-use-in-pediatric-patients
#16
Noritsugu Naito, Yoshiaki Takewa, Satoru Kishimoto, Kei Iizuka, Toshihide Mizuno, Tomonori Tsukiya, Minoru Ono, Eisuke Tatsumi
Although the outcomes of patients with end-stage heart failure treated with implantable left ventricular assist devices have improved, extracorporeal left ventricular assist devices continue to play an important role, especially in pediatric patients. The present study aimed to examine the long-term biocompatibility of a small-sized extracorporeal pneumatic left ventricular assist device (NIPRO-LVAD) used in a 30- to 90-day animal experiment. The NIPRO-LVAD was designed for pediatric patients or small-sized adults...
November 24, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29174824/intraprocedural-invasive-hemodynamic-parameters-as-predictors-of-short-and-long-term-outcomes-in-patients-undergoing-transcatheter-aortic-valve-replacement
#17
Sarkis Kiramijyan, Edward Koifman, Marco A Magalhaes, Itsik Ben-Dor, Romain Didier, Zachary D Jerusalem, Sandeep Kumar, Arpi Tavil-Shatelyan, Toby Rogers, Arie Steinvil, Jiaxiang Gai, Rebecca Torguson, Lowell F Satler, Augusto D Pichard, Ron Waksman
OBJECTIVE: Evaluation of invasive hemodynamic parameters as prognostic markers of mortality in patients undergoing TAVR. BACKGROUND: The value of invasive intraprocedural hemodynamic evaluation of patients undergoing transcatheter aortic valve replacement is unclear. METHODS: Consecutive patients who underwent transfemoral TAVR and had complete prospectively collected intraprocedural invasive hemodynamic parameters were retrospectively analyzed...
September 22, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29174823/modified-balloon-aortic-valvuloplasty-in-fragile-symptomatic-patients-unsuitable-for-both-surgical-and-percutaneous-valve-replacement
#18
Gianluca Rigatelli, Fabio Dell'Avvocata, Luca Conte, Daniela Lanza, Sara Giatti, Pierluigi Del Santo, Loris Roncon, Giuseppe Faggian
BACKGROUND: Balloon Aortic valvuloplasty (BAV) is considered as a bridge therapy to percutaneous valve implantation or a palliative treatment in patients with aortic valve stenosis (AVS). Potential risk of complications, in particular in fragile patients, is still not negligible. AIM: To describe the technique and outcomes of modified BAV in fragile symptomatic patients unsuitable for other treatments using no-pacing and minimally invasive approach. METHODS: Symptomatic fragile patients with severe aortic valve stenosis judged unsuitable by the heart team for surgical or percutaneous valve implantation from 1 September 2013 to 1 September 2017 were offered modified BAV...
October 19, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29171946/-cardiac-rehabilitation-state-of-the-art-2017
#19
REVIEW
P Lancellotti, A Ancion, L Piérard
Cardiovascular disease remains the leading cause of death in western countries. Despite advances in acute management of patients, secondary prevention remains essential and should include cardiac rehabilitation. Recent data have confirmed the interest of this management in the various conventional indications : coronary disease, valvular heart disease, heart failure and heart transplantation. New indications emerge with some benefit that should be evaluated : ventricular assistance, pulmonary hypertension, trans-catheter aortic valve implantation...
November 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29171921/developing-a-clinically-relevant-tissue-engineered-heart-valve-a-review-of-current-approaches
#20
REVIEW
Aline L Y Nachlas, Siyi Li, Michael E Davis
Tissue engineered heart valves (TEHVs) have the potential to address the shortcomings of current implants through the combination of cells and bioactive biomaterials that promote growth and proper mechanical function in physiological conditions. The ideal TEHV should be anti-thrombogenic, biocompatible, durable, and resistant to calcification, and should exhibit a physiological hemodynamic profile. In addition, TEHVs may possess the capability to integrate and grow with somatic growth, eliminating the need for multiple surgeries children must undergo...
November 24, 2017: Advanced Healthcare Materials
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