Read by QxMD icon Read

Heart valve replacement on africa

Trust Saidi, Tania S Douglas
The treatment of rheumatic heart disease presents a medical and surgical challenge, particularly in developing countries, where the disease is prevalent. Most of these countries find it prohibitively expensive to import heart valve prostheses that are required for treatment and are largely manufactured in the United States and Europe. Even if the valves were available, the absence of facilities to conduct open-heart surgery for valve replacement results in many people from developing countries dying needlessly of the disease...
October 2016: Expert Review of Medical Devices
Antonio Grimaldi, Ana Olga Mocumbi, Juergen Freers, Matthias Lachaud, Mariana Mirabel, Beatriz Ferreira, Kumar Narayanan, David S Celermajer, Daniel Sidi, Xavier Jouven, Eloi Marijon
Tropical endomyocardial fibrosis (EMF) is a neglected disease of poverty that afflicts rural populations in tropical low-income countries, with some certain high-prevalence areas. Tropical EMF is characterized by the deposition of fibrous tissue in the endomyocardium, leading to restrictive physiology. Since the first descriptions in Uganda in 1948, high-frequency areas for EMF have included Africa, Asia, and South America. Although there is no clear consensus on a unified hypothesis, it seems likely that dietary, environmental, and infectious factors may combine in a susceptible individual to give rise to an inflammatory process leading to endomyocardial damage and scar formation...
June 14, 2016: Circulation
Samuel Kingué, Serigne Abdou Ba, Dhadi Balde, Mamadou Bocary Diarra, Jean-Baptiste Anzouan-Kacou, Benedict Anisubia, Jean-Marie Damorou, Pierre Ndobo, Alain Menanga, Abdoul Kane, Maurice Kakou-Guikahué, Monique Kenfack, Bernard Metogo, David Chelo, Euloge Yangnigni, Cabral Tantchou, Edmond Bertrand, Jean-Jacques Monsuez
BACKGROUND: There are few African data available on rheumatic heart disease (RHD). AIM: To provide data on the clinical characteristics and treatment of patients with RHD hospitalized in sub-Saharan Africa. METHODS: The VALVAFRIC study is a multicentre hospital-based retrospective registry of patients with RHD hospitalized in African cardiology departments from 2004 to 2008. RESULTS: Among 3441 patients with at least one mild RHD lesion seen on echocardiography in 5 years in 12 cardiology departments from seven countries, 1385 had severe lesions (502 men; 803 women; mean age 29...
May 2016: Archives of Cardiovascular Diseases
E L Benade, B F Jacobson, S Louw, E Schapkaitz
BACKGROUND: Measurement of the international normalised ratio (INR) is essential in the management of patients on long-term warfarin therapy. The CoaguChek XS portable coagulometer is a point-of-care test for INR measurement. It offers the advantage of improved patient accessibility, particularly in peripheral clinics. OBJECTIVES: To evaluate the clinical utility of the CoaguChek XS for monitoring of patients on standard warfarin therapy (INR 2 - 3) as well as those with mechanical heart valve replacements (INR 2...
March 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Jacques Cabral Tantchou Tchoumi, Gianfranco Butera
BACKGROUND: Cardiovascular diseases (CVD) have emerged as a major public health problem and impose an escalating burden on the health care system in Cameroon. The aim of the study was to investigate the preparedness of health care services for patients presenting with CVD in general and specifically, in St. Elizabeth catholic general hospital Shisong, cardiac centre. PATIENTS AND METHODS: Between November 2009 and November 2011, a population of 8,389 adults and 706 children consulted the referral cardiac centre of St...
December 2013: Cardiovascular Diagnosis and Therapy
Yves d'Udekem, Varun Sharma
This article outlines the arguments against cusp extension, which were put forward at the debate entitled "Repair options in rheumatic aortic disease in young patients" at the Symposium on Surgery for Rheumatic Heart Disease organized by The World Society for Pediatric and Congenital Heart Surgery at The Sixth World Congress of Paediatric Cardiology and Cardiac Surgery, February 17-22, 2013, Cape Town, South Africa. We propose that cusp extension should be avoided because (1) these patients are usually old enough to receive the same valve substitutes as adults, (2) lack of antibioprophylaxis compliance will likely result in early reintervention, (3) cusp extension mandates rerepair within four to five years and is more expensive in the long term, and (4) it is fraught with myocardial ischemic complications...
October 2013: World Journal for Pediatric & Congenital Heart Surgery
B Mazibuko, H Ramnarain, J Moodley
BACKGROUND: Cardiac disease in pregnancy is a common problem in under-resourced countries and a significant cause of maternal morbidity and mortality. A large proportion of patients with cardiac disease have prosthetic mechanical heart valve replacements, warranting prophylactic anticoagulation. AIM: To evaluate obstetric outcomes in women with prosthetic heart valves in an under-resourced country. METHODS: A retrospective chart review was performed of 61 pregnant patients with prosthetic valve prostheses referred to our tertiary hospital over a five-year period...
May 2012: Cardiovascular Journal of Africa
Maboury Diao, Adama Kane, Mouhamadou Bamba Ndiaye, Alassane Mbaye, Malick Bodian, Mouhamadoul Mounir Dia, Moustapha Sarr, Abdoul Kane, Jean-Jacques Monsuez, Serigne Abdou Ba
BACKGROUND: Although previous studies showed that pregnancy with heart disease is associated with significant complications, few focused on patients with valvular heart disease in sub-Saharan Africa. METHODS: We report maternal and foetal outcomes in 50 pregnant women with heart disease admitted to the Department of Cardiology of the University of Dakar, during an 8-year period. RESULTS: Rheumatic heart disease was observed in 46 women, seven of whom had previously been operated on...
June 2011: Archives of Cardiovascular Diseases
Lezelle Botes, Johannes Jacobus van den Heever, Francis Edwin Smit, William Morris Leonard Neethling
The history of using homologous cardiac valves dates back more than 30 years. Through the years emphasis was placed on the optimization of graft retrieval, preservation techniques and clinical application. A cardiac homograft valve bank was established at the Department of Cardiothoracic Surgery, University of the Free State, Bloemfontein in 1982. A retrospective analysis was performed on all allograft data since 1984. Since the first valve was successfully procured and transplanted in 1984, 2,540 aortic and pulmonary homografts were harvested from 1,792 donors, of which 1,545 [989 (64%) aortic and 556 (36%) pulmonary] were released for clinical use...
March 2012: Cell and Tissue Banking
Karen Sliwa, Melinda Carrington, Bongani M Mayosi, Elias Zigiriadis, Robert Mvungi, Simon Stewart
AIMS: Little is known on the incidence and clinical characteristics of newly diagnosed rheumatic heart disease (RHD) in adulthood from urban African communities in epidemiologic transition. METHODS AND RESULTS: Chris Hani Baragwanath Hospital services the black African community of 1.1 million people in Soweto, South Africa. A prospective, clinical registry captured data from all de novo cases of structural and functional valvular heart disease (VHD) presenting to the Cardiology Unit during 2006/07...
March 2010: European Heart Journal
E Schapkaitz, B F Jacobson, P Becker, G Conway
BACKGROUND AND OBJECTIVES: Long-term anticoagulation therapy is essential to prevent thrombo-embolic events in patients with mechanical valve replacements. In order to offer indigent patients mechanical heart valve replacement surgery, dedicated anticoagulation clinics are necessary for follow-up. This study assessed the safety and efficacy of lifelong oral anticoagulation therapy in Johannesburg General Hospital mechanical heart valve replacement recipients. The incidence of bleeding and thrombo-embolic complications was documented in three groups of patients with mechanical valve replacements...
August 2006: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
O-W Mensah, A Friedl, A Fried, M Jepsen, A Auricchio, H Klein, C Huth
We present the case of a 23-year-old African professional footballer who was admitted on April 1, 1999 to the Cardiology Department of the University Hospital in Magdeburg, on an emergency basis, from a regional lung clinic. According to the history, he was involved in a collision with an opposing player during a football match in his country (in Africa). He lost consciousness for a short time, but continued playing to the end of the match. About two months later he was invited by a German football club for a check-up, with the view to ultimately playing for the club...
August 2005: Thoracic and Cardiovascular Surgeon
Ulrich O von Oppell, Zeead Karani, Andre Brooks, Johan Brink
BACKGROUND AND AIM OF THE STUDY: The chemical glue, gelatin, resorcin and formaldehyde (GRF) is widely used to obliterate the false lumen of acute dissected aortic wall tissue. METHODS: A retrospective review of 41 consecutive patients operated upon for ascending aortic dissection between 1993 and 2000 was conducted. This study focused on 19 patients with acute aortic dissection in whom the aortic valve was resuspended and GRF glue used in the proximal aortic sinuses...
March 2002: Journal of Heart Valve Disease
Visvanathan, Manjarez, Zabriskie
There have been numerous reports stating that treatment of acute rheumatic fever with either aspirin or corticosteroids does not alter the long-term outcome of rheumatic heart disease. Yet, it should be emphasized that most of these studies were carried out with the first generic corticosteroids before the advent of the more active and more potent corticosteroid agents. In spite of this caveat, there is no question that all the clinical and laboratory parameters of inflammation (erythrocyte sedimentation rate, C-reactive protein) return to normal much more rapidly with corticosteroids than with aspirin alone...
October 1999: Current Treatment Options in Cardiovascular Medicine
J W Louw, R H Kinsley, R A Dion, P R Colsen, R W Girdwood
The results of 170 emergency heart valve procedures performed during a 4 1/2-year period were analyzed. Five pathological groups of patients were recognized: those with infective endocarditis (Group 1, 28 patients); acute rheumatic carditis (Group 2, 43 patients); previous valve operation (Group 3, 29 patients); acute-on-chronic cardiac disease (Group 4, 67 patients); and miscellaneous conditions (Group 5, 3 patients). Mitral, aortic, and multiple valve procedures were performed on 58, 65, and 44 patients, respectively...
May 1980: Annals of Thoracic Surgery
M M Parry, D K Cooper, C N Barnard
A review has been undertaken of the number and types of surgical procedures performed in the Department of Cardiac Surgery of the University of Cape Town during the 11-year period 1971-1981, together with data on associated mortality. A yearly average of 560 operations was carried out, of which 75% were for acquired and 25% for congenital heart disease. The number of patients treated continues to rise, from 434 in 1971 to 690 in 1981. There has been a slight reduction in the overall average yearly mortality, from 6...
February 5, 1983: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
M J Antunes, R H Kinsley
The long term results of mitral valve annuloplasty for pure mitral regurgitation are assessed. Thirty-three of the 100 patients (mean age 16 years) had acute rheumatic carditis at the time of operation. Three basic techniques were used: measured asymmetrical annuloplasty (Reed) in 37 patients, posterior plication annuloplasty in 56, Carpentier ring in seven. There were six early deaths, two of which were valve related. The mean follow up period for surviving patients was 4.8 (SD 1.2) years (range 3-9 years)...
October 1983: Thorax
I Oberhaensli, B Friedli, J Cox, D Metras
Endomyocardial fibrosis is a rare disease in children and has been mainly observed in tropical Africa, seldom in Europe. Its precise aetiology remains unknown. New surgical procedures have recently led to better survival. Four children, a 5 year old Swiss boy and 3 African girls, aged 12 to 14 years, were submitted with global heart failure class III to IV of the NYHA classification. Two patients had eosinophilia on admission. A third had a history of transient eosinophilia. The echocardiographic examination showed a very typical picture...
January 6, 1989: Wiener Klinische Wochenschrift
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"