keyword
https://read.qxmd.com/read/38624165/fortified-dual-spectral-overlap-with-enhanced-colorimetric-fluorescence-dual-response-immunochromatography-for-on-site-bimodal-type-gentamicin-monitoring
#21
JOURNAL ARTICLE
Sijie Liu, Cong Zhao, Rui Shu, Leina Dou, Xing Luo, Linpin Luo, Jing Sun, Yanru Wang, Yanwei Ji, Jianlong Wang
Immunochromatography (ICA) remains untapped toward enhanced sensitivity and applicability for fulfilling the nuts and bolts of on-site food safety surveillance. Herein, we report a fortified dual-spectral overlap with enhanced colorimetric/fluorescence dual-response ICA for on-site bimodal-type gentamicin (Gen) monitoring by employing polydopamine (PDA)-coated AuNPs (APDA) simultaneously serving as a colorimetric reporter and a fluorescence quencher. Availing of the enhanced colorimetric response that originated from the PDA layer, the resultant APDA exhibits less required antibody and immunoprobes in a single immunoassay, which facilitates improved antibody utilization efficiency and immuno-recognition in APDA-ICA...
April 16, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38623303/some-distance-measures-for-pythagorean-cubic-fuzzy-sets-application-selection-in-optimal-treatment-for-depression-and-anxiety
#22
JOURNAL ARTICLE
Muhammad Rahim, Fazli Amin, Kamal Shah, Thabet Abdeljawad, Sadique Ahmad
Pythagorean cubic fuzzy sets represent an advancement beyond conventional interval-valued Pythagorean sets, integrating the principles of Pythagorean fuzzy sets and interval-valued Pythagorean fuzzy sets. Given the critical significance of distance measures in real-world decision-making and pattern recognition tasks, it is noteworthy that there exists a notable gap in the literature regarding distance measures specifically tailored for Pythagorean cubic fuzzy sets. The objectives of this paper are:•To define novel generalized distance measures between Pythagorean cubic fuzzy sets (PCFSs) to tackle intricate decision-making challenges...
June 2024: MethodsX
https://read.qxmd.com/read/38622787/nucleic-acid-materials-mediated-innate-immune-activation-for-cancer-immunotherapy
#23
JOURNAL ARTICLE
Xinyu Xu, Yuxuan Hong, Huanhuan Fan, Zijian Guo
Abnormally localized nucleic acids (NAs) are considered as pathogen associated molecular patterns (PAMPs) in innate immunity. They are recognized by NAs-specific pattern recognition receptors (PRRs), leading to the activation of associated signaling pathways and subsequent production of type I interferons (IFNs) and pro-inflammatory cytokines, which further trigger the adaptive immunity. Notably, NAs-mediated innate immune activation is highly dependent on the conformation changes, especially the aggregation of PRRs...
April 15, 2024: ChemMedChem
https://read.qxmd.com/read/38622396/endothelial-mitochondria-associated-membranes-mams-isolation-by-percoll-step-gradients
#24
JOURNAL ARTICLE
Margaret Baldini, Cheng Zhang, Jun Yu
Mitochondria-associated membranes (MAMs) are regions where the endoplasmic reticulum (ER) interacts with mitochondria and regulate lipid trafficking, calcium signaling, ER stress, and inflammation activation. Isolation of MAMs from endothelial cells is vital for studying insight into the immune regulation of many inflammatory diseases. Endothelial cells (ECs) are critical innate immune cells due to their paracrine function of secreting interleukins, chemokines, cytokines, and growth factors, as well as expressing levels of pattern recognition receptors including toll-like receptors (TLRs)...
2024: Methods in Molecular Biology
https://read.qxmd.com/read/38622201/tactile-shape-discrimination-for-moving-stimuli
#25
JOURNAL ARTICLE
Nicolas PĂ©legrin, Mahiko Konishi, Jean-Christophe Sarrazin
In this study, we explored spatial-temporal dependencies and their impact on the tactile perception of moving objects. Building on previous research linking visual perception and human movement, we examined if an imputed motion mechanism operates within the tactile modality. We focused on how biological coherence between space and time, characteristic of human movement, influences tactile perception. An experiment was designed wherein participants were stimulated on their right palm with tactile patterns, either ambiguous (incongruent conditions) or non-ambiguous (congruent conditions) relative to a biological motion law (two-thirds power law) and asked to report perceived shape and associated confidence...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38622187/selecting-an-optimal-approach-to-reduce-energy-crises-under-interval-valued-intuitionistic-fuzzy-environment
#26
JOURNAL ARTICLE
Dilshad Alghazzawi, Hanan Alolaiyan, Humaira Ashfaq, Umer Shuaib, Hamiden Abd El-Wahed Khalifa, Heba Ghareeb Gomaa, Qin Xin
The concept of interval-valued intuitionistic fuzzy sets is intellectually stimulating and holds significant utility in the representation and analysis of real-world problems. The development of similarity measures within the class of interval-valued intuitionistic fuzzy sets possesses significant importance across various academic disciplines, particularly in the fields of decision-making and pattern recognition. The utilization of similarity measures is of utmost importance in the decision-making process when implementing interval-valued intuitionistic fuzzy sets...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38621655/re-repair-after-translocation-of-an-anomalous-left-coronary-artery
#27
Alejandro Fernandez-Cisneros, Eric Feins, Jane Newburger, Sepehr Sekhavat, Bryan Quinn, Luis Quinonez
We repaired a left anomalous aortic origin of coronary artery (AAOCA) using coronary ostium translocation/re-implantation. Re-repair was required due to suboptimal flow pattern in postoperative transesophageal echocardiography (TEE), confirmed with coronary angiography. We emphasize the importance of early recognition, diagnosis and intervention to deal with a problem with the coronary repair.
April 13, 2024: Annals of Thoracic Surgery
https://read.qxmd.com/read/38621142/gentrification-drives-patterns-of-alpha-and-beta-diversity-in-cities
#28
JOURNAL ARTICLE
Mason Fidino, Heather A Sander, Jesse S Lewis, Elizabeth W Lehrer, Kimberly Rivera, Maureen H Murray, Henry C Adams, Anna Kase, Andrea Flores, Theodore Stankowich, Christopher J Schell, Carmen M Salsbury, Adam T Rohnke, Mark J Jordan, Austin M Green, Ashley R Gramza, Amanda J Zellmer, Jacque Williamson, Thilina D Surasinghe, Hunter Storm, Kimberly L Sparks, Travis J Ryan, Katie R Remine, Mary E Pendergast, Kayleigh Mullen, Darren E Minier, Christopher R Middaugh, Amy L Mertl, Maureen R McClung, Robert A Long, Rachel N Larson, Michel T Kohl, Lavendar R Harris, Courtney T Hall, Jeffrey D Haight, David Drake, Alyssa M Davidge, Ann O Cheek, Christopher P Bloch, Elizabeth G Biro, Whitney J B Anthonysamy, Julia L Angstmann, Maximilian L Allen, Solny A Adalsteinsson, Anne G Short Gianotti, Jalene M LaMontagne, Tiziana A Gelmi-Candusso, Seth B Magle
While there is increasing recognition that social processes in cities like gentrification have ecological consequences, we lack nuanced understanding of the ways gentrification affects urban biodiversity. We analyzed a large camera trap dataset of mammals (>500 g) to evaluate how gentrification impacts species richness and community composition across 23 US cities. After controlling for the negative effect of impervious cover, gentrified parts of cities had the highest mammal species richness. Change in community composition was associated with gentrification in a few cities, which were mostly located along the West Coast...
April 23, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38619959/efficient-and-stable-unsupervised-feature-selection-based-on-novel-structured-graph-and-data-discrepancy-learning
#29
JOURNAL ARTICLE
Pei Huang, Zhaoming Kong, Limin Wang, Xuming Han, Xiaowei Yang
Unsupervised feature selection is an important tool in data mining, machine learning, and pattern recognition. Although data labels are often missing, the number of data classes can be known and exploited in many scenarios. Therefore, a structured graph, whose number of connected components is identical to the number of data classes, has been proposed and is frequently applied in unsupervised feature selection. However, methods based on the structured graph learning face two problems. First, their structured graphs are not always guaranteed to maintain the same number of connected components as the data classes with existing optimization algorithms...
April 15, 2024: IEEE Transactions on Neural Networks and Learning Systems
https://read.qxmd.com/read/38619951/learning-to-sketch-a-neural-approach-to-item-frequency-estimation-in-streaming-data
#30
JOURNAL ARTICLE
Yukun Cao, Yuan Feng, Hairu Wang, Xike Xie, S Kevin Zhou
Recently, there has been a trend of designing neural data structures to go beyond handcrafted data structures by leveraging patterns of data distributions for better accuracy and adaptivity. Sketches are widely used data structures in real-time web analysis, network monitoring, and self-driving to estimate item frequencies of data streams within limited space. However, existing sketches have not fully exploited the patterns of the data stream distributions, making it challenging to tightly couple them with neural networks that excel at memorizing pattern information...
April 15, 2024: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://read.qxmd.com/read/38619459/versatile-cu2znsns4-based-synaptic-memristor-for-multi-field-regulated-neuromorphic-applications
#31
JOURNAL ARTICLE
Xiaofei Dong, Hao Sun, Siyuan Li, Xiang Zhang, Jiangtao Chen, Xuqiang Zhang, Yun Zhao, Yan Li
Integrating both electrical and light-modulated multi-type neuromorphic functions in a single synaptic memristive device holds the most potential for realizing next-generation neuromorphic systems, but is still challenging yet achievable. Herein, a simple bi-terminal optoelectronic synaptic memristor is newly proposed based on kesterite Cu2ZnSnS4, exhibiting stable nonvolatile resistive switching with excellent spatial uniformity and unique optoelectronic synaptic behaviors. The device demonstrates not only low switching voltage (-0...
April 21, 2024: Journal of Chemical Physics
https://read.qxmd.com/read/38619287/identification-of-muc1-c-as-a-target-for-suppressing-progression-of-head-and-neck-squamous-cell-carcinomas
#32
JOURNAL ARTICLE
Ayako Nakashoji, Naoki Haratake, Atrayee Bhattacharya, Weipu Mao, Kangjie Xu, Keyi Wang, Tatsuaki Daimon, Hiroki Ozawa, Keisuke Shigeta, Atsushi Fushimi, Nami Yamashita, Yoshihiro Morimoto, Mototsugu Shimokawa, Shin Saito, Ann Marie Egloff, Ravindra Uppaluri, Mark D Long, Donald Kufe
The MUC1-C protein is aberrantly expressed in adenocarcinomas of epithelial barrier tissues and contributes to their progression. Less is known about involvement of MUC1-C in the pathogenesis of squamous cell carcinomas (SCCs). Here, we report that the MUC1 gene is upregulated in advanced head and neck SCCs (HNSCCs). Studies of HNSCC cell lines demonstrate that the MUC1-C subunit regulates expression of (i) RIG-I and MDA5 pattern recognition receptors, (ii) STAT1 and interferon (IFN) regulatory factors, and (iii) downstream IFN-stimulated genes (ISGs)...
April 15, 2024: Cancer Res Commun
https://read.qxmd.com/read/38617928/the-role-of-gender-differences-in-the-outcome-of-juvenile-social-isolation-emphasis-on-changes-in-behavioral-biochemical-and-expression-of-nitric-oxide-synthase-genes-alteration
#33
JOURNAL ARTICLE
Soroush Bijani, Fatemeh Sadat Kashfi, Sadaf Zahedi-Vanjani, Keivan Nedaei, Ali Sharafi, Ali Kalantari-Hesari, Mir-Jamal Hosseini
Social isolation can cause serious problem in performance of individuals in community. As gender differences may cause variation results in the severity of depressive behavior and response of patients to therapy, the impact of gender and the interaction of the level of endocrine secretion in depression were investigated in this study. Wistar rats of both sexes were subjected to post-weaning social isolation (PWSI) conditions and, together with the control group, experienced several behavioral tests including open-field Test (OFT), elevated plus maze (EPM), force swimming test (FST), splash test and novel object recognition test (NOR)...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38617913/efficient-water-related-failure-detection-in-pem-fuel-cells-combining-a-pemfcs-fractional-order-impedance-model-with-fft-pwm-techniques-and-artificial-neural-network-classification
#34
JOURNAL ARTICLE
Fatima Zohra Arama, Slimane Laribi, Khaled Mammar, Nouar Aoun, Touhami Ghaitaoui
Water management and early detection of faults in proton exchange membrane fuel cells (PEMFCs) are among the most critical constraints that limit the optimal spread of this type of energy. Consequently, it is necessary to enhance the reliability and durability of PEMFCs by developing an approach to diagnose and identify water failure modes. This paper proposes an effective and simple method to detect, diagnose, and classify various water failure modes in PEMFCs using a hybrid diagnostic approach. This approach combines the PEMFC fractional order impedance model (FOIM) with fast Fourier transform pulse width modulation (FFT-PWM) techniques and artificial neural network pattern recognition (ANN-PR) classification...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38617834/diversity-pattern-of-insects-from-macao-based-on-an-updated-species-checklist-after-25-years
#35
JOURNAL ARTICLE
Chunlan Xian, Chi Man Leong, Jiuyang Luo, Fenglong Jia, Hongxiang Han, Qiang Xie
BACKGROUND: Insects represent one of the most diverse groups in the organism world with extremely rich species and morphological diversity, playing important roles in natural and city ecosystems. Regional compilation of insect species lists helps to clarify the richness of insect species in a region, enhances our understanding the structure and function of a local ecosystem and promotes the protection and development of insect resources. Moreover, it also serves as a valuable reference for cities with small area, large population and high urbanisation like Macao...
2024: Biodiversity Data Journal
https://read.qxmd.com/read/38616644/blending-indigenous-and-western-science-quantifying-cultural-burning-impacts-in-karuk-aboriginal-territory
#36
JOURNAL ARTICLE
Skye M Greenler, Frank K Lake, William Tripp, Kathy McCovey, Analisa Tripp, Leaf G Hillman, Christopher J Dunn, Susan J Prichard, Paul F Hessburg, Will Harling, John D Bailey
The combined effects of Indigenous fire stewardship and lightning ignitions shaped historical fire regimes, landscape patterns, and available resources in many ecosystems globally. The resulting fire regimes created complex fire-vegetation dynamics that were further influenced by biophysical setting, disturbance history, and climate. While there is increasing recognition of Indigenous fire stewardship among western scientists and managers, the extent and purpose of cultural burning is generally absent from the landscape-fire modeling literature and our understanding of ecosystem processes and development...
April 15, 2024: Ecological Applications
https://read.qxmd.com/read/38615867/exploring-glycans-as-vital-biological-macromolecules-a-comprehensive-review-of-advancements-in-biomedical-frontiers
#37
REVIEW
Kanika Arora, P M Sherilraj, K A Abutwaibe, Bharti Dhruw, Shyam Lal Mudavath
This comprehensive review delves into the intricate landscape of glycans and glycoconjugates, unraveling their multifaceted roles across diverse biological dimensions. From influencing fundamental cellular processes such as signaling, recognition, and adhesion to exerting profound effects at the molecular and genetic levels, these complex carbohydrate structures emerge as linchpins in cellular functions and interactions. The structural diversity of glycoconjugates, which can be specifically classified into glycoproteins, glycolipids, and proteoglycans, underscores their importance in shaping the architecture of cells...
April 12, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38614407/brain-morphological-changes-and-functional-neuroanatomy-related-to-cognitive-and-emotional-distractors-during-working-memory-maintenance-in-post-traumatic-stress-disorder
#38
JOURNAL ARTICLE
Gwang-Won Kim, Jong-Il Park, Jong-Chul Yang
Post-traumatic stress disorder (PTSD) is associated with abnormalities in the processing and regulation of emotion as well as cognitive deficits. This study evaluated the differential brain activation patterns associated with cognitive and emotional distractors during working memory (WM) maintenance for human faces between patients with PTSD and healthy controls (HCs) and assessed the relationship between changes in the activation patterns by the opposing effects of distraction types and gray matter volume (GMV)...
April 11, 2024: Brain Research Bulletin
https://read.qxmd.com/read/38613108/homicide-or-happiness-did-folate-fortification-and-public-health-campaigns-influence-homicide-rates-and-the-great-american-crime-decline
#39
JOURNAL ARTICLE
Stephen J Schoenthaler, Susan L Prescott, Alan C Logan
The last several years have witnessed a remarkable growth in research directed at nutrition and behavior, with increased interest in the field of nutritional criminology. It is becoming clear that dietary patterns and specific nutrients play an important role in cognition and behavior, including those related to aggression, violence, and antisocial activity. Included in this expanding knowledge base is the recognition that folate, through multiple pathways, including enzymatic reactions and gut microbiome ecology, plays a critical role in central nervous system functioning...
April 6, 2024: Nutrients
https://read.qxmd.com/read/38612892/mgmt-profwise-unlocking-a-new-application-for-combined-feature-selection-and-the-rank-based-weighting-method-to-link-mgmt-methylation-status-to-serum-protein-expression-in-patients-with-glioblastoma
#40
JOURNAL ARTICLE
Erdal Tasci, Yajas Shah, Sarisha Jagasia, Ying Zhuge, Jason Shephard, Margaret O Johnson, Olivier Elemento, Thomas Joyce, Shreya Chappidi, Theresa Cooley Zgela, Mary Sproull, Megan Mackey, Kevin Camphausen, Andra Valentina Krauze
Glioblastoma (GBM) is a fatal brain tumor with limited treatment options. O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status is the central molecular biomarker linked to both the response to temozolomide, the standard chemotherapy drug employed for GBM, and to patient survival. However, MGMT status is captured on tumor tissue which, given the difficulty in acquisition, limits the use of this molecular feature for treatment monitoring. MGMT protein expression levels may offer additional insights into the mechanistic understanding of MGMT but, currently, they correlate poorly to promoter methylation...
April 6, 2024: International Journal of Molecular Sciences
keyword
keyword
1470
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.