keyword
MENU ▼
Read by QxMD icon Read
search

Non-invasive

keyword
https://www.readbyqxmd.com/read/28222391/a-clinically-applicable-non-invasive-method-to-quantitatively-assess-the-visco-hyperelastic-properties-of-human-heel-pad-implications-for-assessing-the-risk-of-mechanical-trauma
#1
Sara Behforootan, Panagiotis E Chatzistergos, Nachiappan Chockalingam, Roozbeh Naemi
INTRODUCTION: Pathological conditions such as diabetic foot and plantar heel pain are associated with changes in the mechanical properties of plantar soft tissue. However, the causes and implications of these changes are not yet fully understood. This is mainly because accurate assessment of the mechanical properties of plantar soft tissue in the clinic remains extremely challenging. PURPOSE: To develop a clinically viable non-invasive method of assessing the mechanical properties of the heel pad...
February 9, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28222249/are-non-invasive-fibrosis-markers-for-chronic-hepatitis-b-reliable-in-sub-saharan-africa
#2
Hailemichael Desalegn, Hanna Aberra, Nega Berhe, Svein Gunnar Gundersen, Asgeir Johannessen
BACKGROUND: In the absence of liver biopsy, the World Health Organization (WHO) recommends non-invasive tests, such as APRI (aspartate aminotransferase to platelet ratio index) and FIB-4, to assess liver fibrosis in patients with chronic hepatitis B (CHB). However, these tests are not well validated in sub-Saharan Africa. Recently, a new marker, GPR (gamma-glutamyl transpeptidase to platelet ratio), was found to be more accurate in an African setting, but this needs confirmation in other cohorts...
February 21, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28222046/evaluation-method-for-in-situ-electric-field-in-standardized-human-brain-for-different-transcranial-magnetic-stimulation-coils
#3
Masahiro Iwahashi, Jose Gomez-Tames, Ilkka Laakso, Akimasa Hirata
This study proposes a method to evaluate the electric field induced in the brain by transcranial magnetic stimulation (TMS) to realize focal stimulation in the target area considering the inter-subject difference of the brain anatomy. The TMS is a non-invasive technique used for treatment/diagnosis, and it works by inducing an electric field in a specific area of the brain via a coil-induced magnetic field. Recent studies that report on the electric field distribution in the brain induced by TMS coils have been limited to simplified human brain models or a small number of detailed human brain models...
February 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28222012/effects-of-the-nasal-passage-on-forced-oscillation-lung-function-measurements
#4
Chuong Ngo, Karl Krüger, Thomas Vollmer, Stefan Winter, Bernhard Penzlin, Sylvia Lehmann, Steffen Leonhardt, Berno Misgeld
The forced oscillation technique (FOT) is a non-invasive pulmonary function test which is based on the measurement of respiratory impedance. Recently, promising results were obtained by the application of FOT on patients with respiratory failure and obstructive sleep apnea (OSA). By using a nasal mask instead of a mouthpiece, the influences of the nasal passage and upper shunt alter the measured mechanical impedance. In this paper, we investigated the effects of the nasal passage and mask on FOT measurements from eight healthy subjects...
February 21, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28221361/dynamic-control-of-chirality-and-self-assembly-of-double-stranded-helicates-with-light
#5
Depeng Zhao, Thomas van Leeuwen, Jinling Cheng, Ben L Feringa
Helicity switching in biological and artificial systems is a fundamental process that allows for the dynamic control of structures and their functions. In contrast to chemical approaches to responsive behaviour in helicates, the use of light as an external stimulus offers unique opportunities to invert the chirality of helical structures in a non-invasive manner with high spatiotemporal precision. Here, we report that unidirectional rotary motors with connecting oligobipyridyl ligands, which can dynamically change their chirality upon irradiation, assemble into metal helicates that are responsive to light...
March 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28221015/taking-orders-from-light-photo-switchable-working-inactive-smart-surfaces-for-protein-and-cell-adhesion
#6
Junji Zhang, Wenjing Ma, Xiao-Peng He, He Tian
Photo-responsive smart surfaces are promising candidates for a variety of applications in optoelectronics and sensing devices. The use of light as an order-signal provides advantages of remote and non-invasive control with high temporal and spatial resolutions. Modification of the photo-switches with target bio-macromolecules, such as peptides, DNA and small-molecules including folic acid derivatives and sugars, has recently become a popular strategy to empower the smart surfaces with an improved detection efficiency and specificity...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28220855/extending-calibration-free-force-measurements-to-optically-trapped-rod-shaped-samples
#7
Frederic Català, Ferran Marsà, Mario Montes-Usategui, Arnau Farré, Estela Martín-Badosa
Optical trapping has become an optimal choice for biological research at the microscale due to its non-invasive performance and accessibility for quantitative studies, especially on the forces involved in biological processes. However, reliable force measurements depend on the calibration of the optical traps, which is different for each experiment and hence requires high control of the local variables, especially of the trapped object geometry. Many biological samples have an elongated, rod-like shape, such as chromosomes, intracellular organelles (e...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28220762/drug-detection-in-breath-non-invasive-assessment-of-illicit-or-pharmaceutical-drugs
#8
Phillip Trefz, Svend Kamysek, Patricia Fuchs, Pritam Sukul, Jochen Schubert, Wolfram Miekisch
Breath analysis not only holds great potential for the development of new non-invasive diagnostic methods, but also for the identification and follow up of drug levels in breath. This is of interest for both, forensic and medical science. On the one hand, the detection of drugs of abuse in exhaled breath - similar to the well-known breath alcohol tests - would be highly desirable as an alternative to blood or urine analysis in situations such as police controls for drugged driving. The noninvasive detection of drugs and their metabolites is thus of great interest in forensic science, especially since marijuana is becoming legalized in certain parts of the U...
February 21, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28220697/near-infrared-activated-upconversion-nanoprobes-for-sensitive-endogenous-zn2-detection-and-selective-on-demand-photodynamic-therapy
#9
Ping Hu, Rui Wang, Lei Zhou, Lei Chen, Qingsheng Wu, Ming-Yong Han, Ahmed Mohamed El-Toni, Dongyuan Zhao, Fan Zhang
As a light-activated non-invasive cancer treatment paradigm, photodynamic therapy (PDT) has been attracting extensive attentions because of its high treatment efficacy and low side effects. Especially, spatiotemporal control of singlet oxygen (1O2) release is highly desirable for realizing on-demand PDT, which, however, still remains a huge challenge. To address this issue, a novel switchable near infrared (NIR)-responsive upconversion nanoprobe has been firstly designed and successfully applied for controlled PDT that can be optically activated by tumor-associated disruption of labile Zn2+ (denoted as Zn2+ in the following words) homeostasis stimuli...
February 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28220532/diagnosing-bladder-outlet-obstruction-using-the-penile-cuff-test-in-men-with-lower-urinary-tract-symptoms
#10
Kwang Jin Ko, Yoon Seok Suh, Tae Heon Kim, Hyun Hwan Sung, Gyu Ha Ryu, Kyu-Sung Lee
AIM: The current standard diagnostic test to evaluate bladder outlet obstruction (BOO) is pressure-flow study (PFS). The penile cuff test (PCT) was introduced as a non-invasive alternative to PFS to determine the isovolumetric bladder pressure and also flow rate. The aim of the study was to evaluate the diagnostic accuracy and acceptability of the PCT, compared to those of PFS, in the assessment of BOO in men. METHODS: A total of 146 consecutive men with an International Prostate Symptom Score (IPSS) >12 and lower urinary tract symptoms (LUTS) for >6 months were included in this single-institution, prospective, diagnostic study...
February 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28220524/language-fmri-and-direct-cortical-stimulation-in-epilepsy-preoperative-planning
#11
Alison Austermuehle, John Cocjin, Reynolds Richard, Shubhi Agrawal, Leigh Sepeta, William D Gaillard, Kareem Zaghloul, Sara Inati, William H Theodore
OBJECTIVE: Presurgical language assessment can help minimize damage to eloquent cortex during resective epilepsy surgery. Two methods for presurgical language mapping are functional MRI (fMRI) and direct cortical stimulation (DCS) of implanted subdural electrodes. We compared fMRI results to DCS to help optimize non-invasive language localization and assess its validity. METHODS: We studied 19 patients referred for presurgical evaluation of drug-resistant epilepsy...
February 21, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28220508/quantitative-long-term-measurements-of-burns-in-a-rat-model-using-spatial-frequency-domain-imaging-sfdi-and-laser-speckle-imaging-lsi
#12
Adrien Ponticorvo, David M Burmeister, Rebecca Rowland, Melissa Baldado, Gordon T Kennedy, Rolf Saager, Nicole Bernal, Bernard Choi, Anthony J Durkin
BACKGROUND AND OJECTIVES: The current standard for diagnosis of burn severity and subsequent wound healing is through clinical examination, which is highly subjective. Several new technologies are shifting focus to burn care in an attempt to help quantify not only burn depth but also the progress of healing. While accurate early assessment of partial thickness burns is critical for dictating the course of treatment, the ability to quantitatively monitor wound status over time is critical for understanding treatment efficacy...
February 21, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28220320/a-novel-method-for-non-invasively-detecting-the-severity-and-location-of-aortic-aneurysms
#13
Igor Sazonov, Ashraf W Khir, Wisam S Hacham, Etienne Boileau, Jason M Carson, Raoul van Loon, Colin Ferguson, Perumal Nithiarasu
The influence of an aortic aneurysm on blood flow waveforms is well established, but how to exploit this link for diagnostic purposes still remains challenging. This work uses a combination of experimental and computational modelling to study how aneurysms of various size affect the waveforms. Experimental studies are carried out on fusiform-type aneurysm models, and a comparison of results with those from a one-dimensional fluid-structure interaction model shows close agreement. Further mathematical analysis of these results allows the definition of several indicators that characterize the impact of an aneurysm on waveforms...
February 21, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28220080/validation-of-a-method-for-the-assessment-of-urinary-neopterin-levels-to-monitor-health-status-in-non-human-primate-species
#14
Verena Behringer, Jeroen M G Stevens, Fabian H Leendertz, Gottfried Hohmann, Tobias Deschner
Determining individual health status is of great importance for a better understanding of life history trade-offs between growth, reproduction, and maintenance. However, existing immunological methods are invasive and therefore not suitable for investigating health status in wild populations. Thus, there is an urgent need for non-invasive methods to assess the immune status of animals. Neopterin is involved in the cell-mediated pathway of the immune response (Th1-type), secreted during the activation of monocytes and macrophages...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28220070/neural-correlates-of-mirror-visual-feedback-induced-performance-improvements-a-resting-state-fmri-study
#15
Viola Rjosk, Jöran Lepsien, Elisabeth Kaminski, Maike Hoff, Bernhard Sehm, Christopher J Steele, Arno Villringer, Patrick Ragert
Mirror visual feedback (MVF) is a promising approach to enhance motor performance without training in healthy adults as well as in patients with focal brain lesions. There is preliminary evidence that a functional modulation within and between primary motor cortices as assessed with transcranial magnetic stimulation (TMS) might be one candidate mechanism mediating the observed behavioral effects. Recently, studies using task-based functional magnetic resonance imaging (fMRI) have indicated that MVF-induced functional changes might not be restricted to the primary motor cortex (M1) but also include higher order regions responsible for perceptual-motor coordination and visual attention...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28219828/treating-cognitive-impairment-with-transcranial-low-level-laser-therapy
#16
Jack C de la Torre
This report examines the potential of low level laser therapy (LLLT) to alter brain cell function and neurometabolic pathways using red or near infrared (NIR) wavelengths transcranially for the prevention and treatment of cognitive impairment. Although laser therapy on human tissue has been used for a number of medical conditions since the late 1960s, it is only recently that several clinical studies have shown its value in raising neurometabolic energy levels that can improve cerebral hemodynamics and cognitive abilities in humans...
February 13, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28219721/magnetic-nanoparticles-a-multifunctional-vehicle-for-modern-theranostics
#17
REVIEW
M Angelakeris
Magnetic nanoparticles provide a unique multifunctional vehicle for modern theranostics since they can be remotely and non-invasively employed as imaging probes, carrier vectors and smart actuators. Additionally, special delivery schemes beyond the typical drug delivery such as heat or mechanical stress may be magnetically triggered to promote certain cellular pathways. To start with, we need magnetic nanoparticles with several well-defined and reproducible structural, physical, and chemical features, while bio-magnetic nanoparticle design imposes several additional constraints...
February 17, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28219399/noninvasive-detection-of-alarming-intracranial-pressure-changes-by-auditory-monitoring-in-early-management-of-brain-injury-a-prospective-invasive-versus-noninvasive-study
#18
Fabrice Giraudet, François Longeras, Aurélien Mulliez, Aurélie Thalamy, Bruno Pereira, Paul Avan, Laurent Sakka
BACKGROUND: In brain-injured patients intracranial pressure (ICP) is monitored invasively by a ventricular or intraparenchymal transducer. The procedure requires specific expertise and exposes the patient to complications such as malposition, hemorrhage or infection. As inner-ear fluid compartments are connected to the cerebrospinal fluid space, ICP changes elicit subtle changes in the physiology of the inner ear. Notably, we previously demonstrated that the phase of cochlear microphonic potential (CM) generated by sound stimuli rotates with ICP...
February 21, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28219182/-enrichment-and-detection-of-circulating-tumor-cells-and-its-application-in-head-and-neck-squamous-cell-carcinoma
#19
H D Zhang, Z K Yu
Circulating tumor cells are tumor cells from the primary tumor or metastatic tumor to fall off into the circulatory system. They are closely related to the recurrence and metastasis of tumor. Detection of circulating tumor cells as a "liquid biopsy" , to get the tumor information through non-invasive sampling method. It has the advantages of short time of tumor diagnosis, repeatable operation, and has gradually replaced the traditional biopsy. In this paper, the enrichment and detection of circulating tumor cells and its application in head and neck squamous cell carcinoma were reviewed...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28218976/differential-expression-of-innate-immune-response-genes-in-clinical-phases-of-chronic-hepatitis-b-infection
#20
Sara Romani, Seyed Masoud Hosseini, Seyed Reza Mohebbi, Andre Boonstra, Afsaneh Sharifian
We investigated innate immune gene expression in clinical phases of Chronic Hepatitis B infection, including immune tolerant (IT); immune active (IA); inactive carrier (IC); and hepatitis B e antigen (HBeAg)-negative phases, as well as healthy controls. Expression levels of interferon types I, II, and III, their receptor subunits, IRFs, TLRs and other IFN-induced genes in peripheral blood mononuclear cells were compared.Forty HBsAg-positive treatment-naïve subjects without co-infection with HIV, HCV or HDV were enrolled...
February 20, 2017: Journal of Viral Hepatitis
keyword
keyword
14690
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"