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https://www.readbyqxmd.com/read/29161410/autonomy-affinity-and-the-assessment-of-damages-acb-v-thomson-medical-pte-ltd-2017-sgca-20-and-shaw-v-kovak-2017-ewca-civ-1028
#1
Craig Purshouse
In ACB v Thomson Medical Pte Ltd [2017] SGCA 20 and Shaw v Kovak [2017] EWCA Civ 1028, the idea that 'lost autonomy' should be recognised as a new form of actionable damage in the tort of negligence was rejected in Singapore and England, respectively. This, it will be argued, was the correct outcome. Protecting an interest in autonomy via the tort of negligence would undermine the coherence of that tort. In ACB, however, a new, different, form of damage was recognised: loss of 'genetic affinity'. This commentary will discuss some problems that protecting an interest in 'genetic affinity' raises before critiquing the approach to assessing damages in ACB...
November 17, 2017: Medical Law Review
https://www.readbyqxmd.com/read/29130271/the-impact-of-state-medical-malpractice-reform-on-individual-level-health-care-expenditures
#2
Hao Yu, Michael Greenberg, Amelia Haviland
BACKGROUND: Past studies of the impact of state-level medical malpractice reforms on health spending produced mixed findings. Particularly salient is the evidence gap concerning the effect of different types of malpractice reform. This study aims to fill the gap. It extends the literature by examining the general population, not a subgroup or a specific health condition, and controlling for individual-level sociodemographic and health status. METHODS: We merged the Database of State Tort Law Reforms with the Medical Expenditure Panel Survey between 1996 and 2012...
December 2017: Health Services Research
https://www.readbyqxmd.com/read/29129949/the-effects-of-malpractice-non-economic-damage-caps-on-the-supply-of-physician-labor-heterogeneity-by-physician-age-and-risk
#3
Michael F Pesko, Meagan Cea, Jayme Mendelsohn, Tara F Bishop
We explore the impact of malpractice caps on non-economic damages that were enacted between 2003 and 2006 on the supply of physician labor, separately for high-malpractice risk and low-malpractice risk physician specialty types, and separately by young and old physicians. We use physician data from the Area Resource File for 2000-2011 and malpractice policy data from the Database of State Tort Law Reforms. We study the impact of these caps using a reverse natural experiment, comparing physician supply in nine states enacting new caps to physician supply in ten states that had malpractice caps in place throughout the full time period...
June 2017: International Review of Law and Economics
https://www.readbyqxmd.com/read/29117024/behavioral-genetics-in-criminal-and-civil-courts
#4
Maya Sabatello, Paul S Appelbaum
Although emerging findings in psychiatric and behavioral genetics create hope for improved prevention, diagnosis, and treatment of disorders, the introduction of such data as evidence in criminal and civil proceedings raises a host of ethical, legal, and social issues. Should behavioral and psychiatric genetic data be admissible in judicial proceedings? If so, what are the various means for obtaining such evidence, and for what purposes should its admission be sought and permitted? How could-and should-such evidence affect judicial outcomes in criminal and civil proceedings? And what are the potential implications of using behavioral and psychiatric genetic evidence for individuals and communities, and for societal values of equality and justice? This article provides an overview of the historical and current developments in behavioral genetics...
November 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/29096914/the-medical-incapacity-hold-a-policy-on-the-involuntary-medical-hospitalization-of-patients-who-lack-decisional-capacity
#5
Erick H Cheung, Jonathan Heldt, Thomas Strouse, Paul Schneider
BACKGROUND: Medically hospitalized patients who lack decisional capacity may request, demand, or attempt to leave the hospital despite grave risk to themselves. The treating physician in this scenario must determine how to safeguard such patients, including whether to attempt to keep them in the hospital. However, in many jurisdictions, there are no laws that address this matter directly. In this absence, psychiatrists are often called upon to issue an involuntary psychiatric hold (civil commitment) to keep the patient from leaving...
September 21, 2017: Psychosomatics
https://www.readbyqxmd.com/read/29071448/effects-of-acute-handling-stress-on-short-term-central-expression-of-orexigenic-anorexigenic-genes-in-zebrafish
#6
Raul Cortés, Mariana Teles, Miguel Oliveira, Camino Fierro-Castro, Lluis Tort, José Miguel Cerdá-Reverter
Physiological mechanisms driving stress response in vertebrates are evolutionarily conserved. These mechanisms involve the activation of both the hypothalamic-sympathetic-chromaffin cell (HSC) and the hypothalamic-pituitary-adrenal (HPA) axes. In fish, the reduction of food intake levels is a common feature of the behavioral response to stress but the central mechanisms coordinating the energetic response are not well understood yet. In this work, we explore the effects of acute stress on key central systems regulating food intake in fish as well as on total body cortisol and glucose levels...
October 25, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29068289/medical-malpractice-reform-a-fix-for-a-problem-long-out-of-fashion
#7
Richard Mark Kirkner
State tort reforms have all but relegated the malpractice crisis to the history books. But there's good news for those of you into all things retro: The House of Representatives just voted to fix the malpractice crisis by a 222-197 margin.
October 2017: Managed Care
https://www.readbyqxmd.com/read/29050988/physiological-and-immune-response-of-juvenile-rainbow-trout-to-dietary-bovine-lactoferrin
#8
Trinh Dinh Khuyen, Syaghalirwa N M Mandiki, Valérie Cornet, Jessica Douxfils, Stéphane Betoulle, Peter Bossier, Felipe E Reyes-López, Lluis Tort, Patrick Kestemont
Lactoferrin, a large multifunctional glycoprotein, is involved in many physiological functions but its immunomodulatory pathways are not well characterized in fish. The objective of the present study was to investigate the temporal effect of dietary bovine lactoferrin (BLf) at low (0.1%) and high (1%) on immunological organs of rainbow trout juveniles. BLf diets did not affect specific growth rate, haematocrit, splenic index, spleen respiratory burst activity as well as humoral (mIgM) and neutrophils (MPO) gene expressions after short term - 35 days (D35) and long term nutrient test - 51 days (D51) of feeding...
October 16, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29034379/medical-malpractice-an-introduction-for-the-dental-practitioner
#9
Inbal Blau, Liran Levin
With the plethora of medical malpractice claims, health care providers are forced to deal not only with medical matters but also with legal issues. Thus, unfortunately, every time health care providers give a medical treatment, they should be aware of the legal implications of their act. Most medical malpractice cases will be resolved in civil law and will have financial implications, but in extreme cases (such as causing death by negligence) criminal procedure may also be conducted, meaning criminal sanctions (imprisonment or fine)...
2017: Quintessence International
https://www.readbyqxmd.com/read/29021795/neuroendocrine-and-immune-responses-undertake-different-fates-following-tryptophan-or-methionine-dietary-treatment-tales-from-a-teleost-model
#10
Rita Azeredo, Marina Machado, António Afonso, Camino Fierro-Castro, Felipe E Reyes-López, Lluis Tort, Manuel Gesto, Marta Conde-Sieira, Jesús M Míguez, José L Soengas, Eva Kreuz, Sven Wuertz, Helena Peres, Aires Oliva-Teles, Benjamin Costas
Methionine and tryptophan appear to be fundamental in specific cellular pathways involved in the immune response mechanisms, including stimulation of T-regulatory cells by tryptophan metabolites or pro-inflammatory effects upon methionine supplementation. Thus, the aim of this study was to evaluate the immunomodulatory effect of these amino acids on the inflammatory and neuroendocrine responses in juveniles of European seabass, Dicentrarchus labrax. To achieve this, goal fish were fed for 14 days methionine and tryptophan-supplemented diets (MET and TRP, respectively, 2× dietary requirement level) or a control diet meeting the amino acids requirement levels (CTRL)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28965257/annual-and-intradiurnal-variation-of-dominant-airborne-pollen-and-the-effects-of-meteorological-factors-in-%C3%A3-e%C3%A5-me-izmir-turkey
#11
Ulas Uguz, Aykut Guvensen, Nedret Sengonca Tort
In this present study, airborne pollen in Çeşme was investigated between February 17, 2012 and February 17, 2014 using the volumetric method. Çeşme, one of Turkey's most important tourism centers, which attracts numerous local and foreign tourists each year, is a district of Izmir, a province in the western part of Turkey. During the 2-year study, 12,905 pollen grains belonging to 64 taxa (33 arboreal, 31 non-arboreal plants) were detected. However, the 2-year data results revealed that the taxa with the pollen concentration more than 4% in the atmosphere were Cupressaceae/Taxaceae (4268 pollen, 33...
September 30, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28893179/conservation-and-diversification-of-small-rna-pathways-within-flatworms
#12
Santiago Fontenla, Gabriel Rinaldi, Pablo Smircich, Jose F Tort
BACKGROUND: Small non-coding RNAs, including miRNAs, and gene silencing mediated by RNA interference have been described in free-living and parasitic lineages of flatworms, but only few key factors of the small RNA pathways have been exhaustively investigated in a limited number of species. The availability of flatworm draft genomes and predicted proteomes allowed us to perform an extended survey of the genes involved in small non-coding RNA pathways in this phylum. RESULTS: Overall, findings show that the small non-coding RNA pathways are conserved in all the analyzed flatworm linages; however notable peculiarities were identified...
September 11, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28882798/modulatory-in%C3%A2-vitro-effect-of-stress-hormones-on-the-cytokine-response-of-rainbow-trout-and-gilthead-sea-bream-head-kidney-stimulated-with-vibrio-anguillarum-bacterin
#13
Ali Reza Khansari, David Parra, Felipe E Reyes-López, Lluís Tort
In fish, the stress response and their consequences in the immune system have been widely described. Recently, a differential cytokine regulation between rainbow trout (Oncorhynchus mykiss) and gilthead sea bream (Sparus aurata) was reported after treatment with stress hormones together with their receptor antagonists. Nevertheless, there is no evidence of whether antagonists for stress hormone receptors may influence the interaction between hormones and cytokines after bacterial administration. Thus, the aim of our study was to evaluate the cytokine expression in the presence of stress hormones (cortisol, ACTH, adrenaline), hormone receptor antagonists and inactivated Vibrio anguillarum bacterin in rainbow trout and gilthead sea bream head kidney primary cell culture (HKPCC)...
September 4, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28857959/ovarian-torsion-in-a-pediatric-patient-the-importance-of-repeat-imaging
#14
Christopher Skappak, Jackie L Thurston, April J Kam
A previously healthy 10-year-old girl presented to the emergency department with a 1-day history of abdominal pain. She was afebrile with an elevated white blood cell count and a negative pelvic ultrasound. The pain resolved while in hospital, and the patient was discharged home. The patient returned 10 days later, and the pain now migrated from the left flank to the subumbilical region. The patient now had an elevated white blood cell count and C-reactive protein. On pelvic ultrasound, the patient had a large midline mass and a normal right ovary...
July 3, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28833629/olfactory-bulb-drives-respiration-coupled-beta-oscillations-in-the-rat-hippocampus
#15
André Lv Lockmann, Diego A Laplagne, Adriano Bl Tort
The synchronization of neuronal oscillations has been suggested as a mechanism to coordinate information flow between distant brain regions. In particular, the olfactory bulb (OB) and the hippocampus (HPC) have been shown to exhibit oscillations in the beta frequency range (10-20 Hz) that are likely to support communication between these structures. Here we further characterize features of beta oscillations in OB and HPC of rats anesthetized with urethane. We find that beta oscillations simultaneously appear in HPC and OB and phase-lock across structures...
August 22, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28819301/asymmetry-of-the-temporal-code-for-space-by-hippocampal-place-cells
#16
Bryan C Souza, Adriano B L Tort
Hippocampal place cells convey spatial information through spike frequency ("rate coding") and spike timing relative to the theta phase ("temporal coding"). Whether rate and temporal coding are due to independent or related mechanisms has been the subject of wide debate. Here we show that the spike timing of place cells couples to theta phase before major increases in firing rate, anticipating the animal's entrance into the classical, rate-based place field. In contrast, spikes rapidly decouple from theta as the animal leaves the place field and firing rate decreases...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809585/patient-autonomy-and-doctor-s-concern-a-case-of-intravenous-drug-abuser
#17
Alok Atreya, Tanuj Kanchan, Rajeev K Shah
Intravenous substance abuse is often associated with physical and psychological harm, and often requires urgent medical attention. We report a case of a young male who presented with life-threatening complications of intravenous drug abuse, but refused to give details or agree to the proposed treatment, raising concerns for the team of doctors. A compos mentis patient has a right to decide what should be done to his body. Medical management or surgical interventions cannot be initiated without the patient's consent even if these are lifesaving procedures, or a procedure meant to benefit the patient...
January 1, 2017: Medico-legal Journal
https://www.readbyqxmd.com/read/28743008/wastewater-contamination-in-antarctic-melt-water-streams-evidenced-by-virological-and-organic-molecular-markers
#18
L F L Tort, K Iglesias, C Bueno, A Lizasoain, M Salvo, J Cristina, N Kandratavicius, L Pérez, R Figueira, M C Bícego, S Taniguchi, N Venturini, E Brugnoli, R Colina, M Victoria
Human activities in the Antarctica including tourism and scientific research have been raised substantially in the last century with the concomitant impact on the Antarctic ecosystems through the release of wastewater mainly from different scientific stations activities. The aim of this study was to assess the wastewater contamination of surface waters and sediments of three melt-water streams (11 sites) by leaking septic tanks located in the vicinity of the Uruguayan Scientific Station in the Fildes Peninsula, King George Island, Antarctica, during summer 2015...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28726141/transoral-robotic-thyroidectomy-lessons-learned-from-an-initial-consecutive-series-of-24-patients
#19
Hoon Yub Kim, Young Jun Chai, Gianlorenzo Dionigi, Angkoon Anuwong, Jeremy D Richmon
BACKGROUND: Transoral thyroid surgery is an ideal method for minimally invasive thyroidectomy, as there is less flap dissection during the procedure and no postoperative scars. Nonetheless, technical obstacles have precluded the wide dissemination of this procedure. We present the surgical procedures and outcomes of transoral robotic thyroidectomy (TORT). METHODS: From September 2012 to June 2016, we performed TORT at Korea University Hospital. We used three intraoral ports and a single axillary port for the system's four robotic arms...
July 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28713701/transoral-robotic-thyroidectomy-tort-procedures-and-outcomes
#20
REVIEW
Jeremy D Richmon, Hoon Yub Kim
Remote-access approaches to the thyroid gland have seen a rapid evolution recently with the development of various techniques to minimize the cosmetic and quality-of-life impact of a visible scar. Most approaches have required significantly more tissue dissection and have been limited in their extent to treat contralateral disease. The transoral approach is the most recent iteration of "scarless" thyroidectomy and offers various advantages over other techniques including less tissue dissection, equal access to both sides of the neck, and a superb midline view of the anatomy...
June 2017: Gland Surgery
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