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https://www.readbyqxmd.com/read/29780968/the-influence-of-obesity-on-operating-room-time-and-perioperative-complications-in-cochlear-implantation
#1
Jonathan L Hatch, Isabel M Boersma, Forest W Weir, Michael J Bauschard, Meredith A Holcomb, Paul R Lambert, Ted A Meyer
Objective: The rising incidence of obesity in the United States is associated with increased healthcare expenditures and resource allocation. Obesity has been associated with prolonged operating times during surgical procedures. The primary objective of this study is to compare body mass index (BMI) to length of surgery during cochlear implantation. Methods: A retrospective case control study from a tertiary academic referral center was performed. Patients included were adults who underwent primary, single-sided cochlear implantation with documented BMI and operating room (OR) times from January 2009 to July 2015...
December 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29770134/comparative-immune-and-stress-related-transcript-response-induced-by-air-exposure-and-vibrio-anguillarum-bacterin-in-rainbow-trout-oncorhynchus-mykiss-and-gilthead-seabream-sparus-aurata-mucosal-surfaces
#2
Ali Reza Khansari, Joan Carles Balasch, Eva Vallejos-Vidal, David Parra, Felipe E Reyes-López, Lluís Tort
Fish have to face various environmental challenges that may compromise the efficacy of the immune response in mucosal surfaces. Since the effect of acute stress on mucosal barriers in fish has still not been fully elucidated, we aimed to compare the short-term mucosal stress and immune transcriptomic responses in a freshwater (rainbow trout, Oncorhynchus mykiss ) and a marine fish (gilthead seabream, Sparus aurata ) to bacterial immersion ( Vibrio anguillarum bacterin vaccine) and air exposure stress in skin, gills, and intestine...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29740220/attributing-diseases-to-multiple-pathways-a-causal-pie-modeling-approach
#3
Christine Chen, Wen-Chung Lee
Characterizing the relations between exposures and diseases is the central tenet of epidemiology. Researchers may want to evaluate exposure-disease causation by assessing whether the disease under concern is induced by the various exposures - the so-called "attribution". In this paper, the authors propose a method to attribute diseases to multiple pathways based on the causal-pie model. The method can also be used to evaluate the potential impact of an intervention strategy and to allocate responsibility in tort-law liability issues...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29731296/-sex-and-gender-equity-in-research-rationale-for-the-sager-guidelines-and-recommended-use
#4
Shirin Heidari, Thomas F Babor, Paola De Castro, Sera Tort, Mirjam Curno
BACKGROUND: Sex and gender differences are often overlooked in research design, study implementation and scientific reporting, as well as in general science communication. This oversight limits the generalizability of research findings and their applicability to clinical practice, in particular for women but also for men. This article describes the rationale for an international set of guidelines to encourage a more systematic approach to the reporting of sex and gender in research across disciplines...
May 3, 2018: Gaceta Sanitaria
https://www.readbyqxmd.com/read/29729981/single-state-tort-reform-analysis-perspectives-from-the-volunteer-state-tennessee
#5
Wes Angel, Margaret Ann Mays, Houston Graves, Ina Radtke
No abstract text is available yet for this article.
May 2, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29728081/lead-exposure-may-affect-gingival-health-in-children
#6
Borany Tort, Youn-Hee Choi, Eun-Kyong Kim, Yun-Sook Jung, Mina Ha, Keun-Bae Song, Young-Eun Lee
BACKGROUND: Several studies have reported the harmful effects of lead poisoning. However, the relationship between lead exposure and oral health of children has not been well defined. The aim of this study was to investigate the relationship between blood lead level (BLL) and oral health status of children. METHODS: A total of 351 children (aged 7-15 years) were recruited from the pilot data of the Korean Environmental Health Survey in Children and Adolescents, which was designed to examine environmental exposure and children's health status in South Korea...
May 4, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29725596/substrate-specificity-of-cysteine-proteases-beyond-the-s-2-pocket-mutagenesis-and-molecular-dynamics-investigation-of-fasciola-hepatica-cathepsins-l
#7
Ileana Corvo, Florencia Ferraro, Alicia Merlino, Kathrin Zuberbühler, Anthony J O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Tatiana Basika, Leda Roche, James H McKerrow, Charles S Craik, Conor R Caffrey, José F Tort
Cysteine proteases are widespread in all life kingdoms, being central to diverse physiological processes based on a broad range of substrate specificity. Paralogous Fasciola hepatica cathepsin L proteases are essential to parasite invasion, tissue migration and reproduction. In spite of similarities in their overall sequence and structure, these enzymes often exhibit different substrate specificity. These preferences are principally determined by the amino acid composition of the active site's S2 subsite (pocket) of the enzyme that interacts with the substrate P2 residue (Schetcher and Berger nomenclature)...
2018: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/29710353/iatrogenic-hepatitis-c-virus-transmission-and-safe-injection-practices
#8
Charles M Defendorf, Sindy Paul, George J Scott
Hepatitis C virus (HCV) infection poses significant adverse health effects. Improper use of vials, needles, syringes, intravenous bags, tubing, and connectors for injections and infusions is a current preventable cause of iatrogenic HCV transmission. Numerous cases have demonstrated the need for continued vigilance and the widespread nature of this iatrogenic infection risk across a variety of medical practice settings in the United States. Failure to implement the evidence-based Centers for Disease Control and Prevention (CDC) infection prevention guidelines exposes patients to preventable harm...
May 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29691421/parallel-detection-of-theta-and-respiration-coupled-oscillations-throughout-the-mouse-brain
#9
Adriano B L Tort, Simon Ponsel, Jakob Jessberger, Yevgenij Yanovsky, Jurij Brankačk, Andreas Draguhn
Slow brain oscillations are usually coherent over long distances and thought to link distributed cell assemblies. In mice, theta (5-10 Hz) stands as one of the most studied slow rhythms. However, mice often breathe at theta frequency, and we recently reported that nasal respiration leads to local field potential (LFP) oscillations that are independent of theta. Namely, we showed respiration-coupled oscillations in the hippocampus, prelimbic cortex, and parietal cortex, suggesting that respiration could impose a global brain rhythm...
April 24, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29672092/from-meaning-to-money-translating-injury-into-dollars
#10
Valerie P Hans, Rebecca K Helm, Valerie F Reyna
Legal systems often require the translation of qualitative assessments into quantitative judgments, yet the qualitative-to-quantitative conversion is a challenging, understudied process. We conducted an experimental test of predictions from a new theory of juror damage award decision making, examining how 154 lay people engaged in the translation process in recommending money damages for pain and suffering in a personal injury tort case. The experiment varied the presence, size, and meaningfulness of an anchor number to determine how these factors influenced monetary award judgments, perceived difficulty, and subjective meaningfulness of awards...
April 2018: Law and Human Behavior
https://www.readbyqxmd.com/read/29626077/new-york-city-s-window-guard-policy-four-decades-of-success
#11
Amita Toprani, Martha Robinson, James K Middleton Iii, Ali Hamade, Thomas Merrill
BACKGROUND: Preventing child falls from windows is easily accomplished by installing inexpensive window-limiting devices but window falls remain a common cause of child injuries. This article describes the history and evolution of the New York City (NYC) window guard rule,which requires building owners to install window guards in apartments housing children aged ≤10 years. The NYC window guard rule was the first directive of its kind in the USA when it was adopted in 1976, and it has led to a dramatic and long-lasting reduction in child window fall-related injuries and deaths...
April 6, 2018: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/29605112/ionising-radiation-risk-disclosure-when-should-radiographers-assume-a-duty-to-inform
#12
C W E Younger, C Douglas, H Warren-Forward
INTRODUCTION: Autonomy is a fundamental patient right for ethical practice, and informed consent is the mechanism by which health care professionals ensure this right has been respected. The ethical notion of informed consent has evolved alongside legal developments. Under Australian law, a provider who fails to disclose risk may be found to be in breach of a duty of disclosure, potentially facing legal consequences if the patient experiences harm that is attributable to an undisclosed risk...
May 2018: Radiography
https://www.readbyqxmd.com/read/29594530/parental-awareness-of-testicular-torsion-amongst-irish-parents
#13
Lee Chien Yap, Robert Keenan, Jody Khan, Claudiu Cozman, Catherine Dowling, Ivor Cullen, Frank Darcy
PURPOSE: Testicular torsion is the most concerning underlying cause of acute scrotal pain that can lead to loss of the affected testicle. Whether a torted testicle can be salvaged surgically is directly affected by prompt presentation and diagnosis. This study aims to evaluate the awareness of testicular torsion amongst Irish parents and evaluate their response to a potential torsion. METHODS: An anonymous questionnaire was distributed to parents attending general paediatric clinics and an acute paediatric unit in two paediatric tertiary referral centres...
March 29, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29580465/quorum-sensing-system-regulated-genes-affect-the-spoilage-potential-of-shewanella-baltica
#14
Linglin Fu, Chong Wang, Nana Liu, Aijin Ma, Yanbo Wang
Large yellow croaker (Pseudosciaena crocea) is a popular and nutritious but also highly perishable fish species, with Shewanella baltica being the primary spoilage bacteria during low-temperature storage. Clarifying the factors promoting spoilage will facilitate efforts to predict and control the shelf life of foods. This study focused on spoilage-related genes in two Shewanella baltica strains with different spoilage potentials. Using whole genome sequencing and alignment, three distinguishing genes (torT, cysM and trxB) were identified...
May 2018: Food Research International
https://www.readbyqxmd.com/read/29574261/the-expression-of-trpv-channels-prostaglandin-e2-and-pro-inflammatory-cytokines-during-behavioural-fever-in-fish
#15
Sebastian Boltana, Nataly Sanhueza, Andrea Donoso, Andrea Aguilar, Diego Crespo, Daniela Vergara, Gabriel Arriagada, Byron Morales-Lange, Luis Mercado, Sonia Rey, Lluis Tort, Simon Mackenzie
A fever, or increased body temperature, is a symptom of inflammation, which is a complex defence reaction of the organism to pathogenic infections. After pathogens enter the body, immune cells secrete a number of agents, the functions of which stimulate the body to develop a functional immune and fever response. In mammals it is known that PGE2 is the principal mediator of fever. The extent to which PGE2 and other pro-inflammatory cytokines such as TNF-α, IL-6, or IL-1β could be involved in the induction of behavioural fever in fish remains to be clarified...
March 21, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29571768/immune-related-gene-expression-and-physiological-responses-in-rainbow-trout-oncorhynchus-mykiss-after-intraperitoneal-administration-of-rhodomyrtus-tomentosa-leaf-extract-a-potent-phytoimmunostimulant
#16
Pinanong Na-Phatthalung, Mariana Teles, Supayang Piyawan Voravuthikunchai, Lluís Tort, Camino Fierro-Castro
The immunostimulatory effects of Rhodomyrtus tomentosa leaf extract were evaluated in rainbow trout through changes in expression profile of genes involved in innate immune and antioxidant response, hematology and stress indicators. The concentrations of R. tomentosa at 10 and 100 μg per fish were administrated by intraperitoneal injection, alone or in combination with LPS. After 6 h of administrtion, the gene expression was measured in head kidney, spleen, and intestine. Results indicated that R. tomentosa exerted immunostimulatory effects by inducing the expression of il10, saa, hepcidin, and sod in head kidney and the expression of il10, tgfβ, and inos in intestine...
March 20, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29571072/european-psychiatric-association-epa-guidance-on-forensic-psychiatry-evidence-based-assessment-and-treatment-of-mentally-disordered-offenders
#17
Birgit A Völlm, Martin Clarke, Vicenç Tort Herrando, Allan O Seppänen, Paweł Gosek, Janusz Heitzman, Erik Bulten
Forensic psychiatry in Europe is a specialty primarily concerned with individuals who have either offended or present a risk of doing so, and who also suffer from a psychiatric condition. These mentally disordered offenders (MDOs) are often cared for in secure psychiatric environments or prisons. In this guidance paper we first present an overview of the field of forensic psychiatry from a European perspective. We then present a review of the literature summarising the evidence on the assessment and treatment of MDOs under the following headings: The forensic psychiatrist as expert witness, risk, treatment settings for mentally disordered offenders, and what works for MDOs...
March 20, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29564721/evaluation-of-bacterial-contamination-as-an-indicator-of-viral-contamination-in-a-sedimentary-aquifer-in-uruguay
#18
P Gamazo, M Victoria, J F Schijven, E Alvareda, L F L Tort, J Ramos, L Burutaran, M Olivera, A Lizasoain, G Sapriza, M Castells, R Colina
In Uruguay, groundwater is frequently used for agricultural activities, as well as for human consumption in urban and rural areas. As in many countries worldwide, drinking water microbiological quality is evaluated only according to bacteriological standards and virological analyses are not mentioned in the legislation. In this work, the incidence of human viral (Rotavirus A, Norovirus GII, and human Adenovirus) and bacterial (total and thermotolerant coliform and Pseudomonas aeruginosa) contamination in groundwater in the Salto district, Uruguay, as well as the possible correlation between these groups of microorganisms, was studied...
March 21, 2018: Food and Environmental Virology
https://www.readbyqxmd.com/read/29560651/acute-toxic-hepatitis-induced-by-a-herbal-medicine-anchusa-boraginaceae
#19
Y F Cagin, Y Seckin, F Firat, E Samdanci
BACKGROUND AND AIM: Herbal treatments are becoming increasingly popular in many countries. Anchusa Boraginaceae (also called Tort plant and beef tongue) is commonly used as a herbal medicine in Elazıg region as diuretic and in the treatment of ulcers, and it is stated that this has no adverse effect. We report a case of acute hepatitis associated with long time use of high doses of Anchusa Boraginaceae. CASE: A 43-year-old male patient is drinking water of Anchusa Boraginaceae that is boiling for 14 days to dissolve the stones in the gallbladder...
October 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29501534/functional-evidence-for-the-inflammatory-reflex-in-teleosts-a-novel-%C3%AE-7-nicotinic-acetylcholine-receptor-modulates-the-macrophage-response-to-dsrna
#20
Débora Torrealba, Joan Carles Balasch, Manuel Criado, Lluís Tort, Simon Mackenzie, Nerea Roher
The inflammatory reflex modulates the innate immune system, keeping in check the detrimental consequences of overstimulation. A key player controlling the inflammatory reflex is the alpha 7 acetylcholine receptor (α7nAChR). This receptor is one of the signalling molecules regulating cytokine expression in macrophages. In this study, we characterize a novel teleost α7nAChR. Protein sequence analysis shows a high degree of conservation with mammalian orthologs and trout α7nAChR has all the features and essential amino acids to form a fully functional receptor...
July 2018: Developmental and Comparative Immunology
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