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Cross-frequency coupling

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https://www.readbyqxmd.com/read/28912698/altered-rich-club-and-frequency-dependent-subnetwork-organization-in-mild-traumatic-brain-injury-a-meg-resting-state-study
#1
Marios Antonakakis, Stavros I Dimitriadis, Michalis Zervakis, Andrew C Papanicolaou, George Zouridakis
Functional brain connectivity networks exhibit "small-world" characteristics and some of these networks follow a "rich-club" organization, whereby a few nodes of high connectivity (hubs) tend to connect more densely among themselves than to nodes of lower connectivity. The Current study followed an "attack strategy" to compare the rich-club and small-world network organization models using Magnetoencephalographic (MEG) recordings from mild traumatic brain injury (mTBI) patients and neurologically healthy controls to identify the topology that describes the underlying intrinsic brain network organization...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28911672/rapid-investigation-of-%C3%AE-glucosidase-inhibitory-activity-of-phaleria-macrocarpa-extracts-using-ftir-atr-based-fingerprinting
#2
Sabina Easmin, Md Zaidul Islam Sarker, Kashif Ghafoor, Sahena Ferdosh, Juliana Jaffri, Md Eaqub Ali, Hamed Mirhosseini, Fahad Y Al-Juhaimi, Vikneswari Perumal, Alfi Khatib
Phaleria macrocarpa, known as "Mahkota Dewa", is a widely used medicinal plant in Malaysia. This study focused on the characterization of α-glucosidase inhibitory activity of P. macrocarpa extracts using Fourier transform infrared spectroscopy (FTIR)-based metabolomics. P. macrocarpa and its extracts contain thousands of compounds having synergistic effect. Generally, their variability exists, and there are many active components in meager amounts. Thus, the conventional measurement methods of a single component for the quality control are time consuming, laborious, expensive, and unreliable...
April 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28904678/-epidemiological-profile-of-hemoglobinopathies-a-cross-sectional-and-descriptive-index-case-study
#3
Fatima Dahmani, Souad Benkirane, Jaafar Kouzih, Aziz Woumki, Hassan Mamad, Azlarab Masrar
Hemoglobinopathies are congenital disorders resultimg from hemoglobin abnormalities. Major forms are often severe, their management is difficult and associated with a great psychosocial impact on patients and their families. They are classified as rare diseases and are still insufficiently known by health professionals. This lack of knowledge is at the origin of diagnostic errors, delay in their management and therefore high morbidity and mortality rate for these patients. In 2008, the World Health Organization (WHO) has published data on hemoglobinopathies epidemiology: more than 330...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28902209/application-of-the-eckart-frame-to-soft-matter-rotation-of-star-polymers-under-shear-flow
#4
Jurij Sablić, Rafael Delgado-Buscalioni, Matej Praprotnik
The Eckart co-rotating frame is used to analyze the dynamics of star polymers under shear flow, either in melt or solution and with different types of bonds. This formalism is compared with the standard approach used in many previous studies on polymer dynamics, where an apparent angular velocity ω is obtained from the relation between the tensor of inertia and angular momentum. A common mistake is to interpret ω as the molecular rotation frequency, which is only valid for rigid-body rotation. The Eckart frame, originally formulated to analyze the infrared spectra of small molecules, dissects different kinds of displacements: vibrations without angular momentum, pure rotation, and vibrational angular momentum (leading to a Coriolis cross-term)...
September 13, 2017: Soft Matter
https://www.readbyqxmd.com/read/28898353/in-vivo-chemotherapeutic-insight-of-a-novel-isocoumarin-3-hexyl-5-7-dimethoxy-isochromen-1-one-genotoxicity-cell-death-induction-leukometry-and-phagocytic-evaluation
#5
Flávio Henrique Souza de Araújo, Débora Rojas de Figueiredo, Sarah Alves Auharek, João Renato Pesarini, Alisson Meza, Roberto da Silva Gomes, Antônio Carlos Duenhas Monreal, Andréia Conceição Milan Brochado Antoniolli-Silva, Dênis Pires de Lima, Candida Aparecida Leite Kassuya, Adilson Beatriz, Rodrigo Juliano Oliveira
Chemotherapy is one of the major approaches for the treatment of cancer. Therefore, the development of new chemotherapy drugs is an important aspect of medicinal chemistry. Chemotherapeutic agents include isocoumarins, which are privileged structures with potential antitumoral activity. Herein, a new 3-substituted isocoumarin was synthesized from 2-iodo-3,5-dimethoxy-benzoic acid and oct-1-yne in a cross-coupling Sonogashira reaction followed by a copper iodide-catalyzed intramolecular cyclization as key step using MeOH/Et3N as the solvent system...
July 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28887885/unveiling-neural-coupling-within-the-sensorimotor-system-directionality-and-nonlinearity
#6
Yuan Yang, Julius P A Dewald, Frans C T van der Helm, Alfred C Schouten
Neural coupling between the central nervous system and the periphery is essential for the neural control of movement. Corticomuscular coherence is a popular linear technique to assess synchronized oscillatory activity in the sensorimotor system. This oscillatory coupling originates from ascending somatosensory feedback and descending motor commands. However, corticomuscular coherence cannot separate this bi-directionality. Furthermore, the sensorimotor system is nonlinear, resulting in cross-frequency coupling...
September 9, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28887385/prior-learning-of-relevant-non-aversive-information-is-a-boundary-condition-for-avoidance-memory-reconsolidation-in-the-rat-hippocampus
#7
Andressa Radiske, Maria Carolina Gonzalez, Sergio Conde-Ocaziones, Anatildes Feitosa, Cristiano A Köhler, Lia R Bevilaqua, Martín Cammarota
Reactivated memories can be modified during reconsolidation, making this process a potential therapeutic target for post-traumatic stress disorder (PTSD), a mental illness characterized by the recurring avoidance of situations that evoke trauma-related fears. However, avoidance memory reconsolidation depends on a set of still loosely defined boundary conditions, limiting the translational value of basic research. In particular, the involvement of the hippocampus in fear-motivated avoidance memory reconsolidation remains controversial...
September 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28881258/time-frequency-analysis-to-a-particular-type-of-scattering-problems-involving-metallic-polymer-tubing-structures
#8
Abdelkader Elhanaoui, Elhoucein Aassif, Gérard Maze, Dominique Décultot
In this paper, recent studies of backscattered acoustic signals in thinner steel-polymer tubing structures have been presented. Reassigned smoothed pseudo Wigner-Ville (rspWV) analysis has been adopted in order to diminish the cross-term effect, and achieve high resolution spectral. Vibration modes, which are associated to the resonances of circumferential waves, have been determined by using the modal isolation plan representation. At normalized frequencies below 140, an appreciable influence from the polymer coating thickness on the A0(+) and S0 modes has been noticed...
August 19, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28869639/analysis-of-the-influence-of-the-transducer-and-its-coupling-layer-on-round-window-stimulation
#9
Houguang Liu, Dan Xu, Jianhua Yang, Shanguo Yang, Gang Cheng, Xinsheng Huang
PURPOSE: In this work, a finite element study is proposed to evaluate the effects of the transducer and its coupling layer on the performance of round window (RW) stimulation. METHODS: Based on a set of micro-computer tomography images of a healthy adult's right ear and reverse engineering technique, a coupled finite-element model of the human ear and the transducer was constructed and verified. Then, the effect of the cross-section of the transducer, the elastic modulus of the coupling layer, the mass of the transducer, and the preload of the transducer were studied...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/28853221/male-urinary-paracetamol-and-semen-quality
#10
M M Smarr, K Kannan, Z Chen, S Kim, G M Buck Louis
The endocrine-disrupting properties of paracetamol have been previously demonstrated in rodent studies of abnormal sperm morphology and diminished testosterone production, in addition to epidemiologic studies of diminished couple fecundity. In this study, we examined the relationship between paracetamol and its metabolite p-aminophenol quantified in a single spot urine and semen quality among 501 male partners of couples planning for pregnancy. Men provided a urine specimen and two fresh semen samples collected approximately one month apart and underwent 24-h analysis for 35 semen quality parameters...
August 29, 2017: Andrology
https://www.readbyqxmd.com/read/28837317/designing-pd-n-heterocyclic-carbene-complexes-for-high-reactivity-and-selectivity-for-cross-coupling-applications
#11
Robert D J Froese, Christopher Lombardi, Matthew Pompeo, Richard P Rucker, Michael G Organ
Over the past decade, the use of Pd-NHC complexes in cross-coupling applications has blossomed, and reactions that were either not previously possible or possible only under very forcing conditions (e.g., > 100 °C, strong base) are now feasible under mild conditions (e.g., room temperature, weak base). Access to tools such as computational chemistry has facilitated a much greater mechanistic understanding of catalytic cycles, which has enabled the design of new NHC ligands and accelerated advances in cross-coupling...
August 24, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28836548/epidemiological-survey-and-risk-factor-analysis-of-recurrent-spontaneous-miscarriages-in-infertile-women-at-large-infertility-centers
#12
Hai-Yan Wang, Jie Qiao, Xiao-Xi Sun, Shu-Yu Wang, Xiao-Yan Liang, Yun Sun, Feng-Hua Liu
BACKGROUND: A higher frequency of spontaneous miscarriage has been observed in infertile couples, and there is a higher prevalence of infertility among patients with a history of recurrent spontaneous miscarriages (RSMs; ≥2 miscarriages). This study aimed to determine the proportion of infertile patients with RSM and examine risk factors associated in patients with RSM being treated with assisted reproductive technologies. METHODS: This cross-sectional observational study was conducted at six reproductive medicine centers in three cities of China...
September 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28831009/band-gap-formation-and-anderson-localization-in-disordered-photonic-materials-with-structural-correlations
#13
Luis S Froufe-Pérez, Michael Engel, Juan José Sáenz, Frank Scheffold
Disordered dielectric materials with structural correlations show unconventional optical behavior: They can be transparent to long-wavelength radiation, while at the same time have isotropic band gaps in another frequency range. This phenomenon raises fundamental questions concerning photon transport through disordered media. While optical transparency in these materials is robust against recurrent multiple scattering, little is known about other transport regimes like diffusive multiple scattering or Anderson localization...
August 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28821753/dynamic-reconfiguration-of-cortical-functional-connectivity-across-brain-states
#14
Iain Stitt, Karl J Hollensteiner, Edgar Galindo-Leon, Florian Pieper, Eva Fiedler, Thomas Stieglitz, Gerhard Engler, Guido Nolte, Andreas K Engel
Throughout each day, the brain displays transient changes in state, as evidenced by shifts in behavior and vigilance. While the electrophysiological correlates of brain states have been studied for some time, it remains unclear how large-scale cortico-cortical functional connectivity systematically reconfigures across states. Here, we investigate state-dependent shifts in cortical functional connectivity by recording local field potentials (LFPs) during spontaneous behavioral transitions in the ferret using chronically implanted micro-electrocorticographic (µECoG) arrays positioned over occipital, parietal, and temporal cortical regions...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28798683/enhanced-gamma-activity-and-cross-frequency-interaction-of-resting-state-electroencephalographic-oscillations-in-patients-with-alzheimer-s-disease
#15
Jing Wang, Yuxing Fang, Xiao Wang, Huichao Yang, Xin Yu, Huali Wang
Cognitive impairment, functional decline and behavioral symptoms that characterize Alzheimer's disease (AD) are associated with perturbations of the neuronal network. The typical electroencephalographic (EEG) features in AD patients are increased delta or theta rhythm and decreased alpha or beta rhythm activities. However, considering the role of cross-frequency couplings in cognition, the alternation of cross-frequency couplings in AD patients is still obscure. This study aims to explore the interaction dynamics between different EEG oscillations in AD patients...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28790178/heteromeric-channels-formed-by-trpc1-trpc4-and-trpc5-define-hippocampal-synaptic-transmission-and-working-memory
#16
Jenny Bröker-Lai, Astrid Kollewe, Barbara Schindeldecker, Jörg Pohle, Vivan Nguyen Chi, Ilka Mathar, Raul Guzman, Yvonne Schwarz, Alan Lai, Petra Weißgerber, Herbert Schwegler, Alexander Dietrich, Martin Both, Rolf Sprengel, Andreas Draguhn, Georg Köhr, Bernd Fakler, Veit Flockerzi, Dieter Bruns, Marc Freichel
Canonical transient receptor potential (TRPC) channels influence various neuronal functions. Using quantitative high-resolution mass spectrometry, we demonstrate that TRPC1, TRPC4, and TRPC5 assemble into heteromultimers with each other, but not with other TRP family members in the mouse brain and hippocampus. In hippocampal neurons from Trpc1/Trpc4/Trpc5-triple-knockout (Trpc1/4/5(-/-)) mice, lacking any TRPC1-, TRPC4-, or TRPC5-containing channels, action potential-triggered excitatory postsynaptic currents (EPSCs) were significantly reduced, whereas frequency, amplitude, and kinetics of quantal miniature EPSC signaling remained unchanged...
September 15, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28757194/time-resolved-phase-amplitude-coupling-in-neural-oscillations
#17
Soheila Samiee, Sylvain Baillet
Cross-frequency coupling between neural oscillations is a phenomenon observed across spatial scales in a wide range of preparations, including human non-invasive electrophysiology. Although the functional role and mechanisms involved are not entirely understood, the concept of interdependent neural oscillations drives an active field of research to comprehend the ubiquitous polyrhythmic activity of the brain, beyond empirical observations. Phase-amplitude coupling, a particular form of cross-frequency coupling between bursts of high-frequency oscillations and the phase of lower frequency rhythms, has recently received considerable attention...
July 27, 2017: NeuroImage
https://www.readbyqxmd.com/read/28737378/quantitative-mid-infrared-cavity-ringdown-detection-of-methyl-iodide-for-monitoring-applications
#18
Ibrahim Sadiek, Qiang Shi, Douglas W R Wallace, Gernot Friedrichs
Methyl iodide is a toxic halocarbon with diverse industrial and agricultural applications, and it is an important ocean-derived trace gas that contributes to the iodine burden of the atmosphere. Quantitative analysis of CH3I is mostly based on gas chromatography coupled with mass spectrometry or electron capture detection (GC-MS/ECD) as of yet, which often limits the ability to conduct in situ high-frequency monitoring studies. This work presents an alternative detection scheme based on mid-infrared continuous wave cavity ringdown spectroscopy (mid-IR cw-CRDS)...
August 4, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28735144/entorhinal-tau-pathology-disrupts-hippocampal-prefrontal-oscillatory-coupling-during-associative-learning
#19
Stephanie E Tanninen, Bardia Nouriziabari, Mark D Morrissey, Rami Bakir, Robert D Dayton, Ronald L Klein, Kaori Takehara-Nishiuchi
A neural signature of asymptomatic preclinical Alzheimer's disease (AD) is disrupted connectivity between brain regions; however, its underlying mechanisms remain unknown. Here, we tested whether a preclinical pathologic feature, tau aggregation in the entorhinal cortex (EC) is sufficient to disrupt the coordination of local field potentials (LFPs) between its efferent regions. P301L-mutant human tau or green fluorescent protein (GFP) was virally overexpressed in the EC of adult rats. LFPs were recorded from the dorsal hippocampus and prelimbic medial prefrontal cortex while the rats underwent trace eyeblink conditioning where they learned to associate 2 stimuli separated by a short time interval...
July 6, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28713841/design-and-implementation-of-an-optimal-laser-pulse-front-tilting-scheme-for-ultrafast-electron-diffraction-in-reflection-geometry-with-high-temporal-resolution
#20
Francesco Pennacchio, Giovanni M Vanacore, Giulia F Mancini, Malte Oppermann, Rajeswari Jayaraman, Pietro Musumeci, Peter Baum, Fabrizio Carbone
Ultrafast electron diffraction is a powerful technique to investigate out-of-equilibrium atomic dynamics in solids with high temporal resolution. When diffraction is performed in reflection geometry, the main limitation is the mismatch in group velocity between the overlapping pump light and the electron probe pulses, which affects the overall temporal resolution of the experiment. A solution already available in the literature involved pulse front tilt of the pump beam at the sample, providing a sub-picosecond time resolution...
July 2017: Structural Dynamics (Melville, N.Y.)
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