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https://www.readbyqxmd.com/read/29452590/factors-associated-with-persistent-posttraumatic-stress-disorder-among-u-s-military-service-members-and-veterans
#1
Richard F Armenta, Toni Rush, Cynthia A LeardMann, Jeffrey Millegan, Adam Cooper, Charles W Hoge
BACKGROUND: Posttraumatic stress disorder (PTSD) can have long-term and far-reaching impacts on health and social and occupational functioning. This study examined factors associated with persistent PTSD among U.S. service members and veterans. METHODS: Using baseline and follow-up (2001-2013) questionnaire data collected approximately every 3 years from the Millennium Cohort Study, multivariable logistic regression was conducted to determine factors associated with persistent PTSD...
February 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29447217/does-napping-enhance-the-effects-of-cognitive-bias-modification-appraisal-training-an-experimental-study
#2
Marcella L Woud, Jan C Cwik, Simon E Blackwell, Birgit Kleim, Emily A Holmes, Dirk Adolph, Hui Zhang, Jürgen Margraf
Posttraumatic Stress Disorder (PTSD) is characterised by dysfunctional appraisals of the trauma and its consequences including one's own symptoms. Experimental studies have shown that Cognitive Bias Modification-Appraisal (CBM-App) training can reduce dysfunctional interpretations and analog trauma symptoms. One important question is how to enhance the effects of CBM-App. Following work suggesting that sleep has beneficial effects on consolidation processes and can thus improve learning, the present study investigated whether a brief period of sleep (i...
2018: PloS One
https://www.readbyqxmd.com/read/29447051/targeting-crosstalk-between-nuclear-factor-erythroid-derived-2-like-2-and-nuclear-factor-kappa-beta-pathway-by-nrf2-activator-dimethyl-fumarate-in-epileptogenesis
#3
Neha Singh, Sheekha Vijayanti, Lekha Saha
Epilepsy is a complex, chronic neurological disorder characterized by increased and abnormal synchronization of neuronal electrical activity, which is manifested as seizures. It is associated with many comorbid conditions such as depression, anxiety, sleep disorder, psychiatric disorder etc. which consequently causes higher mortality rate. The understanding of its cellular and molecular mechanism is partial, because of which it remains an ongoing health problem, despite the increasing availability of newer antiepileptic drugs...
February 15, 2018: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29445526/intermittent-hypoxia-cardiovascular-disease-and-obstructive-sleep-apnoea
#4
REVIEW
Chris D Turnbull
Obstructive sleep apnoea (OSA) is a common disorder and is associated with cardiovascular disease. Continuous positive airway pressure (CPAP), whilst reducing blood pressure, has not been shown to reduce cardiovascular events when used as a treatment solely for this purpose in patients with previous cardiovascular disease. Developing a better understanding of the mechanisms underlying cardiovascular disease in OSA is important to develop new treatments. Potential causative mechanisms for cardiovascular disease in OSA include arousal induced sympathetic activation, large intrathoracic pressure swings leading to shear stress on the heart and great vessels, and intermittent hypoxia (IH)...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29444712/physical-activity-as-treatment-for-alcohol-use-disorders-fitforchange-study-protocol-for-a-randomized-controlled-trial
#5
Mats Hallgren, Victoria Andersson, Örjan Ekblom, Sven Andréasson
BACKGROUND: Help-seeking for alcohol use disorders (AUDs) is low and traditional treatments are often perceived as stigmatizing. Physical activity has positive effects on mental and physical health which could benefit this population. We propose to compare the effects of aerobic training, yoga, and usual care for AUDs in physically inactive Swedish adults. METHODS: This is a three-group, parallel, single-blind, randomized controlled trial (RCT). In total, 210 adults (aged 18-75 years) diagnosed with an AUD will be invited to participate in a 12-week intervention...
February 14, 2018: Trials
https://www.readbyqxmd.com/read/29441653/cognitive-control-under-stressful-conditions-in-transitional-age-youth-with-bipolar-disorder-diagnostic-and-sleep-related-differences-in-fronto-limbic-activation-patterns
#6
Adriane M Soehner, Tina R Goldstein, Sarah M Gratzmiller, Mary L Phillips, Peter L Franzen
OBJECTIVES: Adults with bipolar disorder (BD) display aberrant activation in fronto-limbic neural circuitry during cognitive control. However, fronto-limbic response to cognitive control, and factors destabilizing this circuitry, remain under-studied during the transition from adolescence to young adulthood in BD. Sleep patterns are disturbed in BD, undergo change in adolescence, and support brain function. Among transitional age youth, BD diagnosis and sleep (duration and variability) were tested as predictors of fronto-limbic response to a stressful cognitive control task...
February 13, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29439005/randomised-controlled-trial-using-a-theory-based-m-health-intervention-to-improve-physical-activity-and-sleep-health-in-adults-the-synergy-study-protocol
#7
Beatrice Murawski, Ronald C Plotnikoff, Anna T Rayward, Corneel Vandelanotte, Wendy J Brown, Mitch J Duncan
INTRODUCTION: There is a need to reduce physical inactivity and poor sleep health in the adult population to decrease chronic disease rates and the associated burden. Given the high prevalence of these risk behaviours, effective interventions with potential for wide reach are warranted. METHODS AND ANALYSIS: The aim of this two-arm RCT will be to test the effect of a three month personalised mobile app intervention on two main outcomes: minutes of moderate-to-vigorous-intensity physical activity and overall sleep quality...
February 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29438400/nocturnal-insomnia-symptoms-and-stress-induced-cognitive-intrusions-in-risk-for-depression-a-2-year-prospective-study
#8
David A Kalmbach, Vivek Pillai, Christopher L Drake
Nearly half of US adults endorse insomnia symptoms. Sleep problems increase risk for depression during stress, but the mechanisms are unclear. During high stress, individuals having difficulty falling or staying asleep may be vulnerable to cognitive intrusions after stressful events, given that the inability to sleep creates a period of unstructured and socially isolated time in bed. We investigated the unique and combined effects of insomnia symptoms and stress-induced cognitive intrusions on risk for incident depression...
2018: PloS One
https://www.readbyqxmd.com/read/29436878/development-of-a-university-campus-healthy-sleep-promotion-program
#9
Brian E McCabe, Adam S Troy, Hersila H Patel, Valerie Halstead, Mayra Arana
This article provides a preliminary evaluation of a campus sleep health program for undergraduate university students. In this study, 5 focus groups with 38 undergraduates assessed perceptions about sleep in relationship to college experiences. Additionally, 35 undergraduate students participated in campus sleep improvement workshops, and completed a brief self-report survey before and after the workshop. Results showed five themes emerged from focus groups: (a) Sleep and its impact on academics, (b) Understanding of the importance of sleep, (c) Procrastination and its impact on sleep, (d) Stress, and (e) Sleep and extracurricular/social activities...
February 13, 2018: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/29433520/intermittent-hypoxia-promotes-melanoma-lung-metastasis-via-oxidative-stress-and-inflammation-responses-in-a-mouse-model-of-obstructive-sleep-apnea
#10
Lian Li, Fangyuan Ren, Chao Qi, Leiqian Xu, Yinshan Fang, Maoli Liang, Jing Feng, Baoyuan Chen, Wen Ning, Jie Cao
BACKGROUND: Recently, increased tumor incidence and cancer-related mortality have been reported among patients with obstructive sleep apnea (OSA). Intermittent hypoxia (IH), the hallmark feature of OSA, contributes to the metastasis of tumors. However, the molecular mechanisms by which tumor metastasis is accelerated by OSA-like IH remain to be elucidated. METHODS: C57BL/6 J male mice were subjected to intravenous injection of B16F10 melanoma cells before receiving IH treatment...
February 12, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29431918/examining-the-psychological-and-emotional-mechanisms-of-mindfulness-that-reduce-stress-to-enhance-healthy-behaviours
#11
Sara J Sagui-Henson, Sara M Levens, Cara L Blevins
Engagement in modifiable health behaviours plays a critical role in the development of chronic illnesses. Research suggests that mindfulness facilitates health-enhancing behaviour, yet the influence of mindfulness on different health behaviours and the mechanisms underlying this association are unclear. This study investigated a mediation model that explores psychological and emotional coping processes (reappraisal, suppression, and psychological flexibility) as mechanisms connecting mindfulness to reduced stress perceptions and reactions, which then predict physical activity, fruit and vegetable consumption, and sleep quality...
February 12, 2018: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/29431371/palpitations-evaluation-in-the-primary-care-setting
#12
Randell K Wexler, Adam Pleister, Subha V Raman
Palpitations are a common problem in the ambulatory primary care setting, and cardiac causes are the most concerning etiology. Psychiatric illness, adverse effects of prescription and over-the-counter medications, and substance use should also be considered. Distinguishing cardiac from noncardiac causes is important because of the risk of sudden death in those with an underlying cardiac etiology. A thorough history and physical examination, followed by targeted diagnostic testing, can distinguish cardiac conditions from other causes of palpitations...
December 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29430839/effects-of-l-carnosine-supplementation-on-sleep-disorders-and-disease-severity-in-autistic-children-a-randomized-controlled-clinical-trial
#13
Zahra Mehrazad-Saber, Sorayya Kheirouri, Seyyed-Gholamreza Noorazar
Sleep disorders are frequently reported in autistic patients. Evidences suggest that increased oxidative stress and reduced antioxidants may play a major role in the pathogenesis of these disorders. Carnosine acts as an antioxidant, antitoxic and neuroprotective agent. The aim of this trial study was to examine the effects of carnosine supplementation on the sleep disorders and severity of autism core symptoms in autistic patients. In this double-blind, randomized clinical trial, 43 autistic patients (31 boys and 12 girls; aged 4 to 16 years) were divided into two groups of carnosine and control that received 500 mg of carnosine and 500 mg of placebo per day for two months, respectively...
February 11, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29427892/how-health-behaviors-link-romantic-relationship-dysfunction-and-physical-health-across-20-years-for-middle-aged-and-older-adults
#14
Patricia N E Roberson, Rebecca L Shorter, Sarah Woods, Jacob Priest
RATIONALE: There has been substantial research linking marital quality to physical health outcomes; however, the mechanisms linking marital quality and physical health have been studied less extensively, especially with longitudinal data. Of the hypothesized mechanisms, only psychological distress (anxiety/depression) and physiological mechanisms (inflammation) have been tested and confirmed. Health behaviors such as diet, exercise, smoking, drinking, and sleeping have not previously been examined as mechanisms linking marital quality and physical health...
February 3, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29427672/the-short-term-impact-of-economic-uncertainty-on-motor-vehicle-collisions
#15
Sotiris Vandoros, Mauricio Avendano, Ichiro Kawachi
Stress and anxiety lead to attention loss and sleep deprivation and may reduce driving performance, increasing the risk of motor vehicle collision. We used evidence from a natural experiment to examine whether daily changes in economic uncertainty, potentially leading to attention or sleep loss, are associated with collisions in Great Britain. Daily data from the economic policy uncertainty index, derived from analysis of daily UK newspapers, were linked to the daily number of motor vehicle collisions in Great Britain over the period 2005-2015, obtained from the Department for Transport...
February 7, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29426653/postoperative-symptom-distress-of-laparoscopic-cholecystectomy-ambulatory-surgery-patients
#16
Jan Odom-Forren, Deborah B Reed, Carrell Rush
PURPOSE: The purposes of this study were to (1) identify symptoms that cause postoperative distress in ambulatory surgery patients; (2) identify symptom management techniques that effectively reduce distress of laparoscopic cholecystectomy (LC) postoperative symptoms at home after ambulatory surgery; and (3) identify facilitators and barriers to self-management of postoperative symptoms. DESIGN: A qualitative descriptive study. METHODS: Two focus groups of ambulatory surgery patients who had experienced a laparoscopic cholecystectomy procedure and their caregivers were queried to elicit understanding of postoperative symptoms and symptom management techniques...
February 6, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29425355/an-initial-report-of-sleep-disorders-in-women-in-the-u-s-military
#17
Dale C Capener, Matthew S Brock, Shana L Hansen, Panagiotis Matsangas, Vincent Mysliwiec
Introduction: Sleep disorders are increasingly recognized in active duty service members (ADSM). While there are multiple studies in male ADSM, there are limited data regarding sleep disorders in women in the military. The purpose of this study was to characterize sleep disorders in female ADSM referred for clinical evaluation to provide a better understanding of this unique population. Materials and Methods: We conducted a retrospective review of female ADSM who underwent a sleep medicine evaluation and an attended polysomnogram (PSG)...
February 7, 2018: Military Medicine
https://www.readbyqxmd.com/read/29425327/sleep-disturbances-in-chronic-pain-neurobiology-assessment-and-treatment-in-physical-therapist-practice
#18
Jo Nijs, Olivier Mairesse, Daniel Neu, Laurence Leysen, Lieven Danneels, Barbara Cagnie, Mira Meeus, Maarten Moens, Kelly Ickmans, Dorien Goubert
Among people with chronic pain, insomnia is highly prevalent, closely related to the mechanism of central sensitization, characterized by low-grade neuroinflammation, and commonly associated with stress or anxiety; in addition, it often does not respond effectively to drug treatments. This review article applies the current understanding of insomnia to clinical practice, including assessment and conservative treatment of insomnia in people with chronic pain. Cognitive-behavioral therapy for insomnia can be efficacious for improvements in sleep initiation, sleep maintenance, perceived sleep quality, and pain interference with daily functioning in people with chronic pain...
February 7, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29420965/environmental-noise-and-the-cardiovascular-system
#19
REVIEW
Thomas Münzel, Frank P Schmidt, Sebastian Steven, Johannes Herzog, Andreas Daiber, Mette Sørensen
Noise has been found associated with annoyance, stress, sleep disturbance, and impaired cognitive performance. Furthermore, epidemiological studies have found that environmental noise is associated with an increased incidence of arterial hypertension, myocardial infarction, heart failure, and stroke. Observational and translational studies indicate that especially nighttime noise increases levels of stress hormones and vascular oxidative stress, which may lead to endothelial dysfunction and arterial hypertension...
February 13, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29420135/impaired-sleep-mediates-the-negative-effects-of-training-load-on-subjective-well-being-in-female-youth-athletes
#20
Andrew Watson, Stacey Brickson
BACKGROUND: Although increased training load (TL) and impaired sleep are associated with decreases in subjective well-being in adult athletes, these relationships among female youth athletes are unclear. It is unknown whether the effects of sleep and TL on well-being are independent or whether alterations in sleep mediate the effects of TL on subjective well-being. HYPOTHESIS: Sleep and TL exert independent effects on subjective well-being among youth athletes, although alterations in sleep mediate a significant portion of the effect of TL on well-being in female youth athletes...
February 1, 2018: Sports Health
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