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https://www.readbyqxmd.com/read/28212445/long-term-effects-of-fetal-undernutrition-on-rat-heart-role-of-hypertension-and-oxidative-stress
#1
Pilar Rodríguez-Rodríguez, Angel L López de Pablo, Concha F García-Prieto, Beatriz Somoza, Begoña Quintana-Villamandos, José J Gómez de Diego, Perla Y Gutierrez-Arzapalo, David Ramiro-Cortijo, M Carmen González, Silvia M Arribas
BACKGROUND AND AIMS: Fetal undernutrition is a risk factor for heart disease in both genders, despite the protection of women against hypertension development. Using a rat model of maternal undernutrition (MUN) we aimed to assess possible sex differences in the development of cardiac alterations and the implication of hypertension and cardiac oxidative stress. METHODS: Male and female offspring from rats fed ad libitum (control) or with 50% of the normal daily intake during the second half of gestation (MUN) were used...
2017: PloS One
https://www.readbyqxmd.com/read/28193304/physiological-response-and-semen-quality-of-rabbit-bucks-supplemented-with-moringa-leaves-ethanolic-extract-during-summer-season
#2
N I El-Desoky, N M Hashem, A Elkomy, Z R Abo-Elezz
Exposure of rabbit bucks to summer heat stress reduces their homeostasis and semen quality leading to a temporal subfertility. The potentiality of ethanolic extract of Moringa oleifera leaves (M. oleifera ethanolic extract (MLEE)) to reduce negative impacts of heat stress on physiological and semen quality traits was investigated. A total of 28 adult V-line rabbit bucks were randomly distributed among four experimental groups of seven rabbits each. The first group received water (placebo) and served as a control (M0)...
February 14, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28185934/corticosteroids-deeply-depress-the-in-vitro-steroidogenic-capacity-of-eurasian-perch-ovary-at-the-end-of-the-reproductive-cycle
#3
S N M Mandiki, S Milla, S Nkogo Robles, P Kestemont
Corticosteroids play positive or negative role in the reproductive mechanisms of many fish species but the physiological contexts relating to such biphasic actions are not well defined. In the present study we investigated to what extent corticosteroids (cortisol-Co, 11-deoxycorticosterone-DOC) hormones may interfere with the steroidogenic capacity of Eurasian perch follicles, and we tested whether the negative interference of corticosteroids may be mitigated by potential stimulating endocrine factors, namely insulin-like growth factor-1 (IGF), human chorionic gonadotropin (HCG) or thyroid hormones (Triidothyronine-T3, thyroxine-T4)...
February 6, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28185602/impaired-hypothalamic-pituitary-testicular-axis-activity-spermatogenesis-and-sperm-function-promote-infertility-in-males-with-lead-poisoning
#4
Jason Gandhi, Rafael J Hernandez, Andrew Chen, Noel L Smith, Yefim R Sheynkin, Gargi Joshi, Sardar Ali Khan
Lead poisoning is a stealthy threat to human physiological systems as chronic exposure can remain asymptomatic for long periods of time before symptoms manifest. We presently review the biophysical mechanisms of lead poisoning that contribute to male infertility. Environmental and occupational exposure of lead may adversely affect the hypothalamic-pituitary-testicular axis, impairing the induction of spermatogenesis. Dysfunction at the reproductive axis, namely testosterone suppression, is most susceptible and irreversible during pubertal development...
February 10, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28178580/dual-hormone-stress-reactivity-predicts-downstream-war-zone-stress-evoked-ptsd
#5
Robert A Josephs, Adam R Cobb, Cynthia L Lancaster, Han-Joo Lee, Michael J Telch
BACKGROUND: The crucial role of the hypothalamic-pituitary-adrenal axis (HPA) in stress-related homeostasis suggests dysregulated HPA involvement in the pathogenesis of post-traumatic stress disorder (PTSD), yet most studies examining linkages between HPA axis measures and PTSD have yielded null findings. One untested explanation for this inconsistency is a failure to account for simultaneous adrenal and gonadal influence. Here we tested the singular and interactive effects of cortisol (CR) and testosterone (TR) reactivity as moderators of war-zone stress evoked PTSD emergence in the war-zone...
January 19, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28177387/evaluation-of-the-influence-of-prenatal-transportation-stress-on-gnrh-stimulated-luteinizing-hormone-and-testosterone-secretion-in-sexually-mature-brahman-bulls
#6
B P Littlejohn, M C Roberts, M N Bedenbaugh, A W Lewis, D A Neuendorff, D G Riley, J A Carroll, R C Vann, M Amstalden, R D Randel, T H Welsh
This study examined the relationship of prenatal transportation stress (PNS) with exogenous GnRH-induced LH and testosterone secretion in sexually mature Brahman bulls. Brahman cows (n = 96; 48 were stressed by transportation at 5 stages of gestation and 48 were controls) produced a calf crop of 85 calves. All bulls (n = 46) from this calf crop were electroejaculated every 2 wk beginning at a scrotal circumference of 24 cm until sexual maturity (SM; i.e., 500 million sperm/ejaculate). The initial 11 control and 12 PNS bulls to reach SM were selected for the experiment...
January 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28167148/the-association-between-male-biased-sex-ratio-and-indicators-of-stress-in-red-spotted-newts
#7
Andrea S Aspbury, Kristine L Grayson, Selamawit Fantaye, Ian Nichols, Miranda Myers-Burton, Xavier Ortiz-Mangual, Caitlin R Gabor
In populations with a male-biased operational sex ratio, coercive mating by males can have fitness consequences for females. One component of reduced fitness for females in populations with a male-biased OSR may be greater activation of the stress response, resulting in higher corticosterone release rates (CORT; a glucocorticoid stress hormone in amphibians). We test the hypothesis that a male-biased sex ratio affects female activity and release rates of CORT and testosterone (T) in male and female red-spotted newts (Notophthalmus viridescens)...
February 3, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28166954/impacts-of-dose-and-time-of-boldenone-and-stanazolol-exposure-in-inflammatory-markers-oxidative-and-nitrosative-stress-and-histopathological-changes-in-the-rat-testes
#8
Andressa Bueno, Fabiano B Carvalho, Jessié M Gutierres, Cibele L Lhamas, Indiara Brusco, Sara M Oliveira, Marta G Amaral, Guilherme Dorneles, Juliana Sorraila, Marta M Duarte, Cinthia M de Andrade
The present study was conducted to analyze the adverse effects of the anabolic steroids boldenone (BOL) and stanazolol (ST) in the reproductive function of male rats. These molecules were administered using three different protocols. In Protocol I, BOL and ST were administered in a higher dose than what is recommended but for a short period. In Protocol II, a moderate dose of these compounds was applied for an intermediate period, whereas in Protocol III a reduced dose was administered but for an extended period...
March 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28166946/preventive-effects-of-supplemental-dietary-zinc-on-heat-induced-damage-in-the-epididymis-of-boars
#9
Zhaojian Li, Yansen Li, Xin Zhou, Yun Cao, Chunmei Li
Hyperthermia in boars reduces growth performance and sperm production. Zinc is an essential trace element in animal nutrition. Here we investigate the effects of dietary zinc on epididymal structure and function in Bama miniature pigs treated with heat exposure and investigate approaches to improve the reproductive performance in summer. Male Bama miniature pigs (n=18; aged 6 months; bodyweight=10.79±0.06kg) were randomly allocated to 3 groups: control group (Control), heat treatment group (HT), and the diet-supplemented and heat treatment group (H+Zn)...
February 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28163205/localization-pattern-of-visfatin-nampt-in-d-galactose-induced-aged-rat-testis
#10
Malsawmhriatzuala Jeremy, Guruswami Gurusubramanian, Vikas Kumar Roy
Aging is a complex irreversible process which leads to decline in body physiology including reproductive activity. Neurological and brain functions defects have been studied in the d-gal induced aging rodent model. However, there is dearth of literature on reproductive aging induced by d-gal treatment. Visfatin is an adipokine which regulates testicular steroidogenesis and its level increases under stress conditions to cope and extend longevity. To the best of our knowledge the expression and localization pattern of visfatin and histological evaluation of d-gal induced aged testis have not been investigated...
February 3, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28159593/short-term-oral-exposure-to-low-doses-of-nano-sized-tio2-and-potential-modulatory-effects-on-intestinal-cells
#11
Maria Grazia Ammendolia, Francesca Iosi, Francesca Maranghi, Roberta Tassinari, Francesco Cubadda, Federica Aureli, Andrea Raggi, Fabiana Superti, Alberto Mantovani, Barbara De Berardis
The present study investigated potential modulatory effects of low doses of nano-sized titanium dioxide (TiO2) on intestinal cells in vivo and in vitro. After short-term exposure to TiO2 nanoparticles in rats, histopathological analysis of intestinal tissues indicated a gender-specific effect with increased length of intestinal villi in male rats only. Moreover the intestinal tissue showed nanoparticle deposition as revealed by ICP-MS determination of titanium. Increased serum testosterone levels were also detected...
January 31, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28133775/review-on-arsenic-induced-toxicity-in-male-reproductive-system-and-its-amelioration
#12
REVIEW
M Zubair, M Ahmad, Z I Qureshi
Arsenic is an environmental toxicant which causes mutagenic, teratogenic and carcinogenic defects. It is used as herbicide, fungicide and rodenticide and results in contamination of air, soil and water. Arsenic is also produced through burning of coal industries. The sludge of factories contaminates the fodder and drinking source of water of human and livestock. Arsenic binds thiol groups in tissue proteins and impairs the function of the proteins. This metal affects the mitochondrial enzymes and interrupts the production of energy...
January 30, 2017: Andrologia
https://www.readbyqxmd.com/read/28126675/rutin-attenuates-h2o2-induced-oxidation-damage-and-apoptosis-in-leydig-cells-by-activating-pi3k-akt-signal-pathways
#13
Jianhua Sun, Heng Wang, Bei Liu, Wenhao Shi, Juanzi Shi, Zhou Zhang, Junping Xing
Oxidative stress is a primary factor in the pathology of male infertility. The strong antioxidative capacity of rutin has been proven by numerous studies, but a protective role in the context of male reproduction remains to be elucidated. To explore the biological role of rutin in protecting male reproductive function and the potential underlying mechanism, H2O2-induced Leydig cells were used as a cell model of oxidation damage. Our findings showed that rutin at concentrations of 10, 20, and 40μmol/L remarkably increased cell survival rate of H2O2-induced Leydig cells to 70...
January 23, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28121800/effects-of-hit-on-physiological-and-hormonal-adaptions-in-well-trained-cyclists
#14
Øystein Sylta, Espen Tønnessen, Øyvind Sandbakk, Daniel Hammarström, Jørgen Danielsen, Knut Skovereng, Bent R Rønnestad, Stephen Seiler
PURPOSE: Investigate development of specific performance adaptions and hormonal responses every 4 week during a 12-week HIT period in groups with different interval-training prescriptions. METHODS: Sixty-three well-trained cyclists performing a 12-week intervention consisting of 2-3 HIT sessionsweek in addition to ad libitum low intensity training. Groups were matched for total training load, but increasing HIT (INC) group (n=23) performed interval-sessions as 4x16 min in week 1-4, 4x8 min in week 5-8 and 4x4 min in week 9-12...
January 23, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28119158/sources-of-variance-within-and-among-young-men-in-concentrations-of-17%C3%AE-estradiol-and-testosterone-in-axillary-perspiration
#15
Brittney Elliott, Cameron Muir, Denys deCatanzaro
The most potent estrogen, 17β-estradiol (E2), and its precursor, testosterone (T), play critical roles in mammalian reproductive processes. Evidence indicates that these steroids are present in bioactive form in the excretions of many male mammals. It has been demonstrated that small lipophilic steroids such as E2 can be absorbed by proximate females from male excretions, arriving in the uterus, brain, and other organs where there are estrogen receptors. We took repeated samples of axillary perspiration from men aged 20-30years during vigorous exercise...
January 21, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28112379/protective-effects-of-physiological-testosterone-on-advanced-glycation-end-product%C3%A2-induced-injury-in-human-endothelial-cells
#16
Yaping Xie, Dan Yu, Jiahua Wu, Lin Li
The effect of testosterone, a sex steroid, on endothelial cells is controversial as it is uncertain if it has a protective effect on them. Whether physiological testosterone can inhibit the deleterious effects of advanced glycation end products (AGEs) on endothelial cells remains to be elucidated. The present study focused on elucidating the effect of testosterone on the injury of endothelial cells induced by AGEs. Human umbilical vein endothelial cells (HUVECs) were cultured in vitro and treated with AGEs in the presence or absence of various concentrations of testosterone...
January 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28111254/neonatal-blockade-of-gaba-a-receptors-alters-behavioral-and-physiological-phenotypes-in-adult-mice
#17
Ali-Akbar Salari, Mohammad Amani
Gamma-aminobutyric acid (GABA) plays an inhibitory role in the mature brain, and has a complex and bidirectional effect in different parts of the immature brain which affects proliferation, migration and differentiation of neurons during development. There is also increasing evidence suggesting that activation or blockade of the GABA-A receptors during early life can induce brain and behavioral abnormalities in adulthood. We investigated whether neonatal blockade of the GABA-A receptors by bicuculline can alter anxiety- and depression-like behaviors, body weight, food intake, corticosterone and testosterone levels in adult mice (postnatal days 80-95)...
January 19, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28102007/effects-of-diet-restriction-and-diet-complexity-on-life-history-strategies-in-side-blotched-lizards-uta-stansburiana
#18
Heather M Skinner, Andrew M Durso, Lorin A Neuman-Lee, Susan L Durham, Sarah D Mueller, Susannah S French
Organisms must balance energy invested into self-maintenance, reproduction, and somatic growth over their lifetime. In this study, the effects of diet restriction and diet complexity on side-blotched lizards (Uta stansburiana) were analyzed. Thirty male lizards, housed in the laboratory, were fed either an ad libitum or a restricted diet for 18 days (phase 1). Individuals from both treatments were then assigned to a diet of the same quantity of food that was either simple (only crickets) or complex (crickets, cockroaches, waxworms, and mealworms) for 35 days (phase 2)...
November 2016: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
https://www.readbyqxmd.com/read/28101122/start-early-does-social-instability-during-the-pre-and-early-postnatal-development-prepare-male-wild-cavies-for-social-challenge-later-in-life
#19
Katja Siegeler, Lars Lewejohann, Klaus Failing, Norbert Sachser, Sylvia Kaiser
BACKGROUND: The social environment the mother experiences during pregnancy and lactation can powerfully influence the offspring's behavioural profile. Our previous studies in wild cavies show that two different social environments during pregnancy and lactation bring about different behavioural strategies of male offspring later in life: An unstable social environment leads to a behavioural camouflage strategy, hypothesised to be beneficial at times of socially challenging situations...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/28077765/acute-embryonic-anoxia-exposure-favours-the-development-of-a-dominant-and-aggressive-phenotype-in-adult-zebrafish
#20
Catherine M Ivy, Cayleih E Robertson, Nicholas J Bernier
Eutrophication and climate change are increasing the incidence of severe hypoxia in fish nursery habitats, yet the programming effects of hypoxia on stress responsiveness in later life are poorly understood. In this study, to investigate whether early hypoxia alters the developmental trajectory of the stress response, zebrafish embryos were exposed to 4 h of anoxia at 36 h post-fertilization and reared to adults when the responses to secondary stressors were assessed. While embryonic anoxia did not affect basal cortisol levels or the cortisol response to hypoxia in later life, it had a marked effect on the responses to a social stressor...
January 11, 2017: Proceedings. Biological Sciences
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