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https://www.readbyqxmd.com/read/29468748/the-effect-of-dietary-soy-intake-on-weight-loss-glycaemic-control-lipid-profiles-and-biomarkers-of-inflammation-and-oxidative-stress-in-women-with-polycystic-ovary-syndrome-a-randomised-clinical-trial
#1
M Karamali, M Kashanian, S Alaeinasab, Z Asemi
BACKGROUND: The present study aimed to evaluate the effects of dietary soy intake on weight loss and metabolic status of patients with polycystic ovary syndrome (PCOS). METHODS: A randomised clinical trial was conducted among 60 women with PCOS. Participants were randomly assigned into two groups to receive either a test diet (n = 30) or a control diet (n = 30) for 8 weeks. Participants in the test group consumed a diet containing 0.8 g protein kg-1 body weight (35% animal proteins, 35% soy protein and 30% vegetable proteins) and participants in the control group consumed a similar diet containing 70% animal proteins and 30% vegetable proteins...
February 22, 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29463354/adrenal-stress-and-physical-performance-during-military-survival-training
#2
Tunde K Szivak, Elaine C Lee, Catherine Saenz, Shawn D Flanagan, Brian C Focht, Jeff S Volek, Carl M Maresh, William J Kraemer
INTRODUCTION: The purpose of this research was to evaluate neuroendocrine and physical performance responses in sailors and Marines undergoing U.S. Navy Survival, Evasion, Resistance, and Escape (SERE) training. METHODS: Participants were 20 men (Age: 25.3 ± 3.6 yr; Height: 178.1 ± 6.1 cm; Weight: 83.7 ± 12.6 kg). Men were further split into high fit (N = 10) and low fit (N = 10) subgroups based on physical fitness test scores. Blood samples were obtained at baseline (T1), stress (T2), and recovery (T3) timepoints, and were analyzed for plasma epinephrine, plasma norepinephrine, plasma dopamine, serum cortisol, serum testosterone, and plasma neuropeptide Y...
February 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29432745/potential-testicular-toxicity-of-gentamicin-in-adult-rats
#3
Hamdy A A Aly, Memy H Hassan
Gentamycin is an aminoglycoside antibiotic commonly used against Gram-negative bacteria. This study was designed to investigate the testicular toxicity of gentamicin in adult rats. Gentamicin was given to rats at 0, 60, 80 or 100 mg/kg/day for 10 consecutive days. The absolute weight of testes reduced significantly in relation to the dose, while gentamicin at a dose of 60 mg/kg did not show any significant change in the relative testes weight. Sperm count and motility and daily sperm production decreased in a dose-related manner...
February 9, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29429513/protective-roles-of-rutin-against-restraint-stress-on-spermatogenesis-in-testes-of-adult-mice
#4
Asif Mehfooz, Quanwei Wei, Kaizhi Zheng, Mohamed Babo Fadlalla, Gracijela Maltasic, Fangxiong Shi
In order to investigate the effects of Rutin against restraint stress, 50 adult male mice were divided into five groups: control, restraint stress (RS), and RS with 2 doses of Rutin treatments. Mice were restrained in a conical tube for 4 h daily and Rutin was injected intraperitoneally for 15 consecutive days. Restraint stress significantly decreases body weights, testis and epididymis weights, thymus weights, visceral fats, serum concentrations of testosterone, sperm counts, sperm motility and sperm viability, while it increases serum epinephrine levels, adrenal gland weights and abnormal sperms...
February 2018: Tissue & Cell
https://www.readbyqxmd.com/read/29425375/impact-of-hypothermic-stress-during-special-operations-training-of-chilean-military-forces
#5
Claudio Nieto Jimenez, Jorge Cajigal Vargas, Vjera Sofia Triantafilo Vladilo, Jose Naranjo Orellana
Introduction: The Chilean Army considers processes that can optimize physical capacities for responding to the impact of situations and given stressors. The study of the effect of hypothermia as a stressor agent (HSA) and its relationship with cardiovascular, hematological, anthropometric, endocrine, and immunological parameters has not been fully addressed experimentally in military populations. Objective: To identify the endocrine, hematological, cardiovascular, and immunological changes caused by HSA and to associate these variables with body composition and physical fitness in the military special operation courses of the Chilean Army...
February 7, 2018: Military Medicine
https://www.readbyqxmd.com/read/29413584/decision-making-financial-risk-aversion-and-behavioral-biases-the-role-of-testosterone-and-stress
#6
John R Nofsinger, Fernando M Patterson, Corey A Shank
We examine the relation between testosterone, cortisol, and financial decisions in a sample of naïve investors. We find that testosterone level is positively related to excess risk-taking, whereas cortisol level is negatively related to excess risk-taking (correlation coefficient [r]: 0.75 and -0.21, respectively). Additionally, we find support for the dual-hormone hypothesis in a financial context. Specifically, the testosterone-to-cortisol ratio is significantly related to loss aversion. Individuals with a higher ratio are 3...
January 27, 2018: Economics and Human Biology
https://www.readbyqxmd.com/read/29408903/vitamin-d-deficiency-causes-inward-hypertrophic-remodeling-and-alters-vascular-reactivity-of-rat-cerebral-arterioles
#7
Éva Pál, Leila Hadjadj, Zoltán Fontányi, Anna Monori-Kiss, Zsuzsanna Mezei, Norbert Lippai, Attila Magyar, Andrea Heinzlmann, Gellért Karvaly, Emil Monos, György Nádasy, Zoltán Benyó, Szabolcs Várbíró
BACKGROUND AND PURPOSE: Vitamin D deficiency (VDD) is a global health problem, which can lead to several pathophysiological consequences including cardiovascular diseases. Its impact on the cerebrovascular system is not well understood. The goal of the present work was to examine the effects of VDD on the morphological, biomechanical and functional properties of cerebral arterioles. METHODS: Four-week-old male Wistar rats (n = 11 per group) were either fed with vitamin D deficient diet or received conventional rat chow with per os vitamin D supplementation...
2018: PloS One
https://www.readbyqxmd.com/read/29407898/social-dominance-affects-the-development-of-sexual-behaviour-but-not-semen-output-in-yearling-bucks
#8
Fernando Sánchez-Dávila, Hugo Bernal Barragán, Alejandro Sergio Del Bosque-González, Rodolfo Ungerfeld
Goats are polygynous seasonal mammals that establish dominant-subordinate relationships, especially in bucks. The aims of this study were to: 1) compare the reproductive development of dominant and subordinate young bucks allocated in dyads, and 2) determine if their previous dominant position affect their response to grouping. Twenty-four young bucks were allocated in dyads when they were 4 mo old, and the dominance position (DP) [dominant (DB) or subordinate buck (SB)] was determined with a test of competition for food...
January 17, 2018: Theriogenology
https://www.readbyqxmd.com/read/29396325/the-response-of-c19-and-some-c21-steroids-during-synacthen-and-insulin-tolerance-test
#9
Kateřina Šimůnková, Michaela Dušková, Lucie Kolatorova, Mikuláš Kosák, Martin Hill, Hana Jandíková, Hana Pospíšilová, Monika Šrámková, Drahomíra Springer, Luboslav Stárka
Testing of the adrenal function with ACTH 1-24 (Synacthen test) or insulin (insulin tolerance test-ITT) is commonly used. The question of ongoing debate is the dose of Synacthen. Moreover, it may be important from the physiological point of view besides measurement of cortisol levels and 17α-hydroxy-progesterone to know also the response of other steroids to these test. The plasma levels of 24 free steroids and their polar conjugates were followed after stimulation of 1 μg, 10 μg and 250 μg of ACTH 1-24 and after insulin administration in thirteen healthy subjects...
January 30, 2018: Steroids
https://www.readbyqxmd.com/read/29389585/effects-of-lemongrass-oil-and-citral-on-hepatic-drug-metabolizing-enzymes-oxidative-stress-and-acetaminophen-toxicity-in-rats
#10
Chien-Chun Li, Hsiang-Fu Yu, Chun-Hua Chang, Yun-Ta Liu, Hsien-Tsung Yao
The essential oil from a lemongrass variety of Cymbopogon flexuosus [lemongrass oil (LO)] is used in various food and aroma industry products and exhibits biological activities, such as anticancer and antimicrobial activities. To investigate the effects of 200 LO (200 mg/kg) and 400 LO (400 mg/kg) and its major component, citral (240 mg/kg), on drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in the liver, male Sprague-Dawley rats were fed a pelleted diet and administered LO or citral by gavage for 2 weeks...
January 2018: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/29387570/protective-effect-of-crocin-against-d-galactose-induced-aging-in-mice
#11
Elaheh Mohammadi, Soghra Mehri, Hasan Badie Bostan, Hossein Hosseinzadeh
Objective: Aging is a multifactorial phenomenon, which attribute to different diseases and abnormalities in living systems. Oxidative stress, which is an important factor in aging, exacerbates this process via different mechanisms. Crocin (CR), one of the active components of saffron showed strong antioxidant effects. In the present study, anti-aging property of crocin was investigated in mice. Materials and Methods: The model of aging was induced using administration of d-galactose (500 mg/kg, s...
January 2018: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/29386028/pulmonary-exposure-to-carbonaceous-nanomaterials-and-sperm-quality
#12
Astrid Skovmand, Anna Jacobsen Lauvås, Preben Christensen, Ulla Vogel, Karin Sørig Hougaard, Sandra Goericke-Pesch
BACKGROUND: Semen quality parameters are potentially affected by nanomaterials in several ways: Inhaled nanosized particles are potent inducers of pulmonary inflammation, leading to the release of inflammatory mediators. Small amounts of particles may translocate from the lungs into the lung capillaries, enter the systemic circulation and ultimately reach the testes. Both the inflammatory response and the particles may induce oxidative stress which can directly affect spermatogenesis...
January 31, 2018: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/29384140/immediate-and-late-effects-of-chronic-stress-in-the-testes-of-prepubertal-and-adult-rats
#13
Carina T Ribeiro, Diogo B De Souza, Waldemar S Costa, Francisco J B Sampaio, Marco A Pereira-Sampaio
The objective of this study was to investigate the effects of chronic stress on the testes of prepubertal and adult rats and to evaluate whether any alterations could be reversed when stress induction is ended. Seventy-six male rats were assigned to eight groups depending on the type of treatment (control or stressed), the age at which stress was initiated (prepubertal or adult), and the time of evaluation (immediate or late). Stress stimuli were applied for 6 weeks. Stressed prepubertal and adult rats evaluated immediately after the last stress stimulus were included in SP-I and SA-I groups, respectively...
January 30, 2018: Asian Journal of Andrology
https://www.readbyqxmd.com/read/29381667/constipation-and-diarrhea-during-the-menopause-transition-and-early-postmenopause-observations-from-the-seattle-midlife-women-s-health-study
#14
Nini G L Callan, Ellen S Mitchell, Margaret M Heitkemper, Nancy F Woods
OBJECTIVE: To assess the relationship of constipation and diarrhea severity during the menopause transition (MT) with age, MT stage, reproductive biomarkers, stress-related biomarkers, and stress-related perceptions. METHODS: From 1990 to 1992, women aged 35 to 55 years were recruited from the greater Seattle area; 291 of them consented to ongoing (1990-2013) annual data collection by daily menstrual calendar, health diary, and annual health questionnaire. A subset (n = 131) provided a first morning voided urine specimen (1997-2013)...
January 29, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29378207/sex-biased-transcriptomic-response-of-the-reproductive-axis-to-stress
#15
Rebecca Calisi, Suzanne H Austin, Andrew S Lang, Matthew D MacManes
Stress is a well-known cause of reproductive dysfunction in many species, including birds, rodents, and humans, though males and females may respond differently. A powerful way to investigate how stress affects reproduction is by examining its effects on a biological system essential for regulating reproduction, the hypothalamic-pituitary-gonadal (HPG) axis. Often this is done by observing how a stressor affects the amount of glucocorticoids, such as cortisol or corticosterone, circulating in the blood and their relationship with a handful of known HPG-producing reproductive hormones, like testosterone and estradiol...
January 26, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29356695/using-polyphenol-derivatives-to-prevent-muscle-wasting
#16
Marc Francaux, Louise Deldicque
PURPOSE OF REVIEW: To highlight recent evidence for the ability of polyphenols and their derivatives to reduce muscle wasting in different pathological states. RECENT FINDINGS: From January 2016 to August 2017, four articles dealt with the effects of polyphenols on muscle wasting, which were all carried out in mice. The four studies found that polyphenols reduced muscle mass loss associated with cancer cachexia, acute inflammation or sciatic nerve section. One study even showed that muscle mass was totally preserved when rutin was added to the diet of mice undergoing cancer cachexia...
January 19, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29356458/corticosterone-transdermal-application-in-toads-rhinella-icterica-effects-on-cellular-and-humoral-immunity-and-steroid-plasma-levels
#17
Vania Regina Assis, Stefanny Christie Monteiro Titon, Nicolle Gilda Teixeira Queiroz-Hazarbassanov, Cristina de Oliveira Massoco, Fernando Ribeiro Gomes
Previous studies in a variety of vertebrates show stressed animals to exhibit acute increases in glucocorticoid levels, with consequences for immune modulation. Chronically elevated glucocorticoid levels are mostly associated with immunosuppression. However, there is still a paucity of knowledge regarding the amphibian physiological reaction to short- and long-term stress conditions, including glucocorticoid effects on the immune response. In order to better clarify the relationship between glucocorticoids and immune response, newly captured Brazilian toads (Rhinella icterica) (1 week in captivity) were subjected to a daily transdermal application (TA), of corticosterone or vehicle, for 30 consecutive days...
April 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356435/correlates-of-melanization-in-multiple-high-and-low-elevation-populations-of-the-lizard-sceloporus-occidentalis-behavior-hormones-and-parasites
#18
Ryan J Seddon, Diana K Hews
Hormones mediate the expression of suites of correlated traits and hence may act either to facilitate or constrain adaptive evolution. Selection on one trait within a hormone-mediated suite of traits may lead to a change in the strength of the hormone signal, causing changes in correlated traits. Growing evidence suggests that melanization, which is in part regulated by hormonal signals, is tightly linked to other traits, such as aggression and stress physiology. Here, we examine six populations of Sceloporus occidentalis lizards differing in degree of melanization (three dark higher-elevation populations and three less-melanized lower-elevation populations) to investigate potential correlations between behavior, hormones, and parasites...
October 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356402/captivity-effects-on-immune-response-and-steroid-plasma-levels-of-a-brazilian-toad-rhinella-schneideri
#19
Stefanny Christie Monteiro Titon, Vania Regina Assis, Braz Titon Junior, Bruna de Oliveira Cassettari, Pedro Augusto Carlos Magno Fernandes, Fernando Ribeiro Gomes
Stressors can increase plasma glucocorticoid (GC) levels and decrease plasma androgen levels in different species of vertebrates. GCs can have immune-enhancing or immunosuppressive effects, which are dependent upon stress duration and intensity. The worldwide decline in amphibian populations is strongly linked to an array of different stressors. The impacts of stress on GCs, androgens, and the immune response are important to clarify and should lead to the better development of conservation strategies. The present study in adult male toads of Rhinella schneideri investigated the effects of captivity (7, 30, and 60 days) on plasma corticosterone (CORT) and plasma testosterone (T), as well as innate immune responses, specifically humoral and cell mediated responses, as indicated by bacterial killing ability (BKA) and phagocytosis by peritoneal cells, respectively...
February 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29350491/reproductive-toxic-impact-of-subchronic-treatment-with-combined-butylparaben-and-triclosan-in-weanling-male-rats
#20
Madeha A Riad, Marwa M Abd-Rabo, Samy A Abd El Aziz, Adel M El Behairy, Mohamed M Badawy
The effect of treatment with combined butylparaben and triclosan on male gonadal toxicity in weanling rats was investigated. All treated groups experienced atrophy in the ventral prostate and seminal vesicle, likewise significant depletion in the number and motility of sperm. Given individually or combined butylparaben and triclosan, significantly decreased testosterone, luteinizing hormone, and follicle-stimulating hormone levels. Individual treatment with tested compounds caused significant elevation in the E2 level, whereas combined treatment did not alter the E2 level...
January 19, 2018: Journal of Biochemical and Molecular Toxicology
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