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Twin separate placenta

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https://www.readbyqxmd.com/read/27906038/craniopagus-parasiticus-a-parasitic-head-protruding-from-temporal-area-of-cranium-a-case-report
#1
Wassihun Nega, Meku Damte, Yonas Girma, Getachew Desta, Mengistu Hailemariam
BACKGROUND: Craniopagus parasiticus is rare with an incidence of approximately four to six cases in 10,000,000 births. In our case, the head of the parasitic twin protruded from the temporal area of the normal twin's cranium. The parasitic twin had two deformed lower limbs, of which one was rudimentary, and long bones of the bilateral lower limbs and some pelvic bone. Dissection of the mass of the parasitic twin's body revealed the intestine but no chest organs or abdominal organs. There was a rudimentary labium but no vaginal opening...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27864846/monochorial-diamniotic-dizygotic-twins-in-a-german-shepherd-dog-a-case-report
#2
C Urhausen, K Wolf, A Beineke, C Dierks, M Schmicke, A Einspanier, A R Günzel-Apel
A 6.5-year-old clinically healthy German Shepherd Dog with regular oestrous cycles of 6 months was presented for pregnancy diagnosis on day 38 after ovulation (p.ov.). Ultrasonography revealed three individual placental sites in progressed resorption and two vital adequately developed foetuses sharing a joint placenta. On days 41 and 48 p.ov., sonographic signs indicated normal development of both foetuses, but on day 52 p.ov., both foetuses were found to be dead. A caesarean section was performed the same day...
November 18, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27135956/distribution-of-third-stage-length-and-risk-factors-for-its-prolongation
#3
Shiri Shinar, Michael Shenhav, Sharon Maslovitz, Ariel Many
Introduction The aim of our study was to demonstrate the distribution of an uncomplicated third stage and to determine the optimal time for manual intervention. Risk factors for a prolonged third stage were studied. Materials and Methods Computerized data of all vaginal deliveries at our L&D unit from 2010 to 2014 were obtained. Cases of complete and spontaneous placental separation were extracted for further analysis. Cases necessitating manual removal of the placenta due to immediate postpartum hemorrhage (PPH) were also excluded...
August 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27127717/histological-appearance-of-placental-solomonization-in-the-treatment-of-twin-twin-transfusion-syndrome
#4
Stephen P Emery, Lananh Nguyen, W Tony Parks
Background Placental laser equatorialization or "solomonization" during treatment for twin-twin transfusion syndrome (TTTS) is associated with improved pregnancy outcomes. Concern exists, however, about the extent of placental injury caused by the technique, and of its ability to create "dichorionization," or complete separation of the fetal vascular circuits. Case Study A "solomonized" placenta was histologically examined for depth of cell damage. Solomonization produces complete devascularization of the chorionic plate, but has minimal effect on the underlying villi...
April 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27034830/decreased-brain-and-placental-perfusion-in-omphalopagus-conjoined-twins-on-fetal-mri
#5
Sureyya Burcu Gorkem, Mehmet Serdar Kutuk, Selim Doganay, Tamer Gunes, Karamehmet Yildiz, Mustafa Kucukaydin
The aim of this study is to evaluate perfusional changes in brain and placenta of omphalopagus conjoined twins and to compare them with singleton fetuses by using diffusion weighted imaging and apparent diffusion coefficient. Fetal MRIs of 28-week-old omphalopagus conjoined twins with a shared liver with two separate gallbladders and portal and hepatic venous systems and three singleton fetuses with unilateral borderline ventriculomegaly at the same gestational week as control group were enrolled retrospectively...
2016: Radiology Research and Practice
https://www.readbyqxmd.com/read/26944881/the-prenatal-environment-in-twin-studies-a-review-on-chorionicity
#6
REVIEW
Kristine Marceau, Minni T B McMaster, Taylor F Smith, Joost G Daams, Catharina E M van Beijsterveldt, Dorret I Boomsma, Valerie S Knopik
A literature search was conducted to identify articles examining the association of chorionicity (e.g., whether twins share a single chorion and thus placenta or have separate chorions/placentas) and genetics, psychiatry/behavior, and neurological manifestations in humans twins and higher-order multiples. The main aim was to assess how frequently chorionicity has been examined in relation to heritability estimates, and to assess which phenotypes may be most sensitive to, or affected by, bias in heritability estimates because of chorionicity...
May 2016: Behavior Genetics
https://www.readbyqxmd.com/read/26830322/the-promoter-methylomes-of-monochorionic-twin-placentas-reveal-intrauterine-growth-restriction-specific-variations-in-the-methylation-patterns
#7
Zhiming He, Hanlin Lu, Huijuan Luo, Fei Gao, Tong Wang, Yu Gao, Qun Fang, Junwen Wang
Intrauterine growth restriction (IUGR) affects the foetus and has a number of pathological consequences throughout life. Recent work has indicated that variations in DNA methylation might cause placental dysfunction, which may be associated with adverse pregnancy complications. Here, we investigated the promoter methylomes of placental shares from seven monochorionic (MC) twins with selective intrauterine growth restriction (sIUGR) using the healthy twin as an ideal control. Our work demonstrated that the IUGR placental shares harboured a distinct DNA hypomethylation pattern and that the methylation variations preferentially occurred in CpG island shores or non-CpG island promoters...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26748158/metabolic-scaling-and-twin-placentas
#8
C M Salafia, N Kiryankova, H Inany, P Charlagorla, M Park, N Khawar, S VanHorn, B Dygulska, P Narula, S Lederman
OBJECTIVE: Do monochorionic (MC) and/or dichorionic (DC) twins show allometric scaling between placental and birth weight (PW, BW)? METHODS: We extracted BW, PW, gestational age (GA) and cord insertion type from 52 MC to 310 DC twins to calculate β. DC twins were analyzed as summed and as individuals if placentas were separate. RESULTS: Mean β for MC (0.78 ± 0.02), DC summed (0.78 ± 0.02), and DC with separate placentas (0.77 ± 0...
January 2016: Placenta
https://www.readbyqxmd.com/read/26689996/hypothesis-acardiac-twin-pregnancies-pathophysiology-based-hypotheses-suggest-risk-prediction-by-pump-acardiac-umbilical-venous-diameter-ratios
#9
Martin J C van Gemert, Lourens R Pistorius, Kurt Benirschke, Gouke J Bonsel, Frank P H A Vandenbussche, K Marieke Paarlberg, Jeroen P H M van den Wijngaard, Peter G J Nikkels
BACKGROUND: A total of 75% of monozygotic twins share 1 monochorionic placenta where placental anastomoses cause several serious complications, for example, acardiac twinning. Acardiac twins lack cardiac function but grow by perfusion of arterial blood from the pump twin. This rare pregnancy has 50% natural pump twin mortality but accurate risk prediction is currently impossible. Recent guidelines suggest prophylactic surgery before 18 weeks, suggesting 50% unnecessary interventions. We hypothesize that (1) adverse pump twin outcome relates to easy-to-measure pump/acardiac umbilical venous diameter (UVD) ratios, representing acardiac perfusion by the pump's excess cardiac output...
February 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/26678052/sharing-a-placenta-is-associated-with-a-greater-similarity-in-dna-methylation-in-monochorionic-versus-dichorionic-twin-pars-in-blood-at-age-14
#10
COMPARATIVE STUDY
Masato Bui, Beben Benyamin, Sonia Shah, Anjali K Henders, Nicholas G Martin, Grant W Montgomery, Allan F McRae
Monozygotic (MZ) twins provide a natural system for investigating developmental plasticity and the potential epigenetic origins of disease. A major difference in the intrauterine environment between MZ pairs is whether they share a common placenta or have separate placentas. Using DNA methylation measured at >400,000 points in the genome on the Illumina HumanMethylation450 array, we demonstrate that the co-twins of MZ pairs (average age of 14) that shared a common placenta (n = 18 pairs) have more similar DNA methylation levels in blood throughout the genome relative to those with separate placentas (n = 16 pairs)...
December 2015: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/26459409/chronic-placental-inflammation-in-twin-pregnancies
#11
Heejin Bang, Go Eun Bae, Ha Young Park, Yeon Mee Kim, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh, Jung-Sun Kim
BACKGROUND: Chronic placental inflammation, such as villitis of unknown etiology (VUE) and chronic chorioamnionitis (CCA), is considered a placental manifestation of maternal anti-fetal rejection. The aim of this study is to investigate its frequency in twin pregnancies compared to singleton pregnancies. METHODS: Three hundred twin placentas and 1,270 singleton placentas were consecutively collected at a tertiary medical center in Seoul, Republic of Korea from 2009 to 2012...
October 2015: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/26117350/consequences-and-economics-of-metritis-in-iranian-holstein-dairy-farms
#12
A Mahnani, A Sadeghi-Sefidmazgi, V E Cabrera
The objectives of this study were (1) to describe the risk factors, incidence, and productive and reproductive consequences of metritis in dairy cows, and (2) to estimate the financial losses associated with metritis using data gathered from 4 Holstein dairy farms in Isfahan, Iran. Calving records from March 2008 to December 2013, comprising 43,488 calvings, were included in the data set. The effects of metritis on productive and reproductive performance were analyzed using a mixed linear model for primiparous and multiparous cows separately and in an overall data set (all cows combined), whereas risk factors on metritis incidence were examined using a multivariable logistical regression model for the overall data set...
September 2015: Journal of Dairy Science
https://www.readbyqxmd.com/read/25851727/why-accurate-knowledge-of-zygosity-is-important-to-twins
#13
COMPARATIVE STUDY
Tessa L Cutler, Kate Murphy, John L Hopper, Louise A Keogh, Yun Dai, Jeffrey M Craig
All same-sex dizygotic (DZ) twins and approximately one-third of monozygotic (MZ) twin pairs have separate placentas, making it impossible to use the number of placentas to determine zygosity. Zygosity determination is further complicated because incorrect assumptions are often made, such as that only DZ pairs have two placentas and that all MZ pairs are phenotypically identical. These assumptions, by twins, their families and health professionals, along with the lack of universal zygosity testing for same-sex twins, has led to confusion within the twin community, yet little research has been conducted with twins about their understanding and assumptions about zygosity...
June 2015: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/24811124/assessment-of-fetal-cell-chimerism-in-transgenic-pig-lines-generated-by-sleeping-beauty-transposition
#14
Wiebke Garrels, Stephanie Holler, Ulrike Taylor, Doris Herrmann, Heiner Niemann, Zoltan Ivics, Wilfried A Kues
Human cells migrate between mother and fetus during pregnancy and persist in the respective host for long-term after birth. Fetal microchimerism occurs also in twins sharing a common placenta or chorion. Whether microchimerism occurs in multiparous mammals such as the domestic pig, where fetuses have separate placentas and chorions, is not well understood. Here, we assessed cell chimerism in litters of wild-type sows inseminated with semen of transposon transgenic boars. Segregation of three independent monomeric transposons ensured an excess of transgenic over non-transgenic offspring in every litter...
2014: PloS One
https://www.readbyqxmd.com/read/24581204/-twin-pregnancy-with-a-complete-hydatiform-mole-and-a-viable-co-twin
#15
Ana Beatriz Godinho, Diana Martins, Cláudia Araújo, Maria Antonieta Melo, Luís Mendes Graça
A complete hydatiform mole coexisting with a live, viable twin is a rare event. The diagnosis is challenging, and is normally achieved only at second trimester. It may be associated with thyrotoxicosis, vaginal bleeding, preeclampsia, fetal death or persistent throphoblastic disease. The authors describe the case of a pregnant woman presenting with first trimester bleeding. Ultrasound revealed a twin pregnancy with a viable twin and another placenta apparently detached. At 16 gestational weeks ultrasound revealed a live fetus with a normal placenta and a separate vacuolated and vascularized mass...
January 2014: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/24557178/15-a-twin-with-a-mole-a-case-report-of-an-extremely-rare-condition-of-molar-pregnancy-with-a-coexisting-fetus-progressing-to-a-viable-infant
#16
Mahtab Farzin, Janice Brewer
INTRODUCTION: Molar pregnancy with a coexisting twin fetus is an extreme rarity. The incidence of such an occurrence ranges from 1 in 10,000 to 100,000 pregnancies and this may increase with the greater use of assisted reproductive techniques. The management of these pregnancies is difficult due to complications such as fetal death, vaginal bleeding, pre-eclampsia and an increase risk for persistent trophoblastic disease. Delivery of a viable term normal infant from this combination is even rarer...
February 2014: Pathology
https://www.readbyqxmd.com/read/24457670/15-a-twin-with-a-mole-a-case-report-of-an-extremely-rare-condition-of-molar-pregnancy-with-a-coexisting-fetus-progressing-to-a-viable-infant
#17
Mahtab Farzin, Janice Brewer
INTRODUCTION: Molar pregnancy with a coexisting twin fetus is an extreme rarity. The incidence of such an occurrence ranges from 1 in 10,000 to 100,000 pregnancies and this may increase with the greater use of assisted reproductive techniques. The management of these pregnancies is difficult due to complications such as fetal death, vaginal bleeding, pre-eclampsia and an increase risk for persistent trophoblastic disease. Delivery of a viable term normal infant from this combination is even rarer...
February 2014: Pathology
https://www.readbyqxmd.com/read/24051494/endoscopic-laser-dichorionization-of-the-placenta-in-the-treatment-of-severe-twin-twin-transfusion-syndrome
#18
MULTICENTER STUDY
Cleisson F A Peralta, Francisca S Molina, Luisa F Gómez, João R Bennini, Orlando Gomes Neto, Ricardo Barini
OBJECTIVES: To describe the results of a technique of laser ablation of placental vessels in the treatment of severe twin-twin transfusion syndrome (TTTS), which is characterized by separation of the fetoplacental vascular territories and dichorionization of the placenta. PATIENTS AND METHODS: Descriptive analysis of TTTS cases treated with the endoscopic laser dichorionization of the placenta (ELDP) procedure. The variables evaluated were the occurrence of reversal of the donor-recipient phenotype, persistence of TTTS or twin anemia-polycythemia sequence (TAPS); gestational age at delivery; discharge from the hospital of at least 1 or 2 live neonates, and incidence of neurological alterations among survivors...
2013: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/23362780/-massive-bleeding-during-and-after-cesarean-section-in-a-patient-receiving-frozen-thawed-embryo-transfer
#19
Akiko Kawakami, Tadahiko Ishiyama, Satoko Kondo, Keiko Omori, Hironobu Iwashita, Takashi Matsukawa
A 30-year-old pregnant woman (151 cm, 49 kg) with twin gestation who had got pregnant with frozen-thawed embryo transfer was scheduled to undergo cesarean section at 37 weeks of gestation. Combined spinal and epidural anesthesia was performed separately at the T12-L1 (epidural) and at the L3-4 interspace (spinal). The sensory anesthesia was extended to T2 and the operation was started. The cesarean delivery was uneventful and healthy 2,370 g and 2,334 g neonates were delivered. Five minutes after the delivery, placenta was removed manually from the uterus...
December 2012: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/23304585/twin-gestation-in-a-septate-bicornuate-uterus
#20
Henry Osazuwa, David Ejenobo
Bicornuate and septate uteri are among the commonest Mullerian anomalies. They are sporadic and fairly distinguished, but hybrid deformities can occur. This combination creates aetiological and clinical difficulties. The alternative theory of concurrent fusion and septal resorption of the Mullerian duct is seen as the basis of the altered foetal embryology, while the favourable outlook of a bicornuate uterus may be offset by the suboptimal implantation across the avascular septum. Obstetric care is based on empirical interventions deduced from case series, with varied and inconsistent outcomes...
2012: Case Reports in Obstetrics and Gynecology
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